产品简要
公司名称 :
MBL International
产品类型 :
抗体
产品名称 :
LC3
目录 :
M152-3
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4E+12
反应物种 :
人类, 小鼠, 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, mass cytometry
更多信息或购买 :
文章摘录数: 43
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:200; 图 7i
Subramanian M, Hyeon S, Das T, Suh Y, Kim Y, Lee J, et al. UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation. Nat Commun. 2021;12:3291 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 s1c
Matsui H, Ito J, Matsui N, Uechi T, Onodera O, Kakita A. Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease. Nat Commun. 2021;12:3101 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 1c
Ogasawara Y, Cheng J, Tatematsu T, Uchida M, Murase O, Yoshikawa S, et al. Long-term autophagy is sustained by activation of CCTβ3 on lipid droplets. Nat Commun. 2020;11:4480 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:300; 图 ev4l
Bera S, Camblor Perujo S, Calleja Barca E, Negrete Hurtado A, Racho J, de Bruyckere E, et al. AP-2 reduces amyloidogenesis by promoting BACE1 trafficking and degradation in neurons. EMBO Rep. 2020;21:e47954 pubmed 出版商
  • 免疫细胞化学; 猕猴; 1:100; 图 7a
Du T, Zhu G, Chen Y, Shi L, Liu D, Liu Y, et al. Anterior thalamic nucleus stimulation protects hippocampal neurons by activating autophagy in epileptic monkeys. Aging (Albany NY). 2020;12:6324-6339 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 4c
Boukhalfa A, Nascimbeni A, Ramel D, Dupont N, Hirsch E, Gayral S, et al. PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress. Nat Commun. 2020;11:294 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 1c
Ye X, Zhu M, Che X, Wang H, Liang X, Wu C, et al. Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formation. J Neuroinflammation. 2020;17:18 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5c
Zhang Y, Thery F, Wu N, Luhmann E, Dussurget O, Foecke M, et al. The in vivo ISGylome links ISG15 to metabolic pathways and autophagy upon Listeria monocytogenes infection. Nat Commun. 2019;10:5383 pubmed 出版商
  • 免疫细胞化学; 人类; 图 7a
Dang A, Teles R, Weiss D, Parvatiyar K, Sarno E, Ochoa M, et al. IL-26 contributes to host defense against intracellular bacteria. J Clin Invest. 2019;129:1926-1939 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4e
Merrill N, Schipper J, Karnes J, Kauffman A, Martin K, Mackeigan J. PI3K-C2? knockdown decreases autophagy and maturation of endocytic vesicles. PLoS ONE. 2017;12:e0184909 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 1b
  • 免疫印迹; 小鼠; 图 1m
Zhao Y, Chen Y, Miao G, Zhao H, Qu W, Li D, et al. The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation. Mol Cell. 2017;67:974-989.e6 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1f
Wei J, Xu H, Meng W. Noncentrosomal microtubules regulate autophagosome transport through CAMSAP2-EB1 cross-talk. FEBS Lett. 2017;591:2379-2393 pubmed 出版商
  • mass cytometry; 人类; 图 1j
  • 流式细胞仪; 人类; 图 2f
See P, Dutertre C, Chen J, Günther P, McGovern N, Irac S, et al. Mapping the human DC lineage through the integration of high-dimensional techniques. Science. 2017;356: pubmed 出版商
  • 流式细胞仪; 人类; 图 st12
Villani A, Satija R, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, et al. Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. Science. 2017;356: pubmed 出版商
  • 流式细胞仪; 人类; 图 s6b
Ribeiro C, Sarrami Forooshani R, Setiawan L, Zijlstra Willems E, van Hamme J, Tigchelaar W, et al. Receptor usage dictates HIV-1 restriction by human TRIM5? in dendritic cell subsets. Nature. 2016;540:448-452 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 1
Andersson A, Andersson B, Lorell C, Raffetseder J, Larsson M, Blomgran R. Autophagy induction targeting mTORC1 enhances Mycobacterium tuberculosis replication in HIV co-infected human macrophages. Sci Rep. 2016;6:28171 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 6b
Follo C, Barbone D, Richards W, Bueno R, Broaddus V. Autophagy initiation correlates with the autophagic flux in 3D models of mesothelioma and with patient outcome. Autophagy. 2016;12:1180-94 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
Tamura Y, Matsunaga Y, Kitaoka Y, Hatta H. Effects of Heat Stress Treatment on Age-dependent Unfolded Protein Response in Different Types of Skeletal Muscle. J Gerontol A Biol Sci Med Sci. 2017;72:299-308 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 4
Zhuang H, Tian W, Li W, Zhang X, Wang J, Yang Y, et al. Autophagic Cell Death and Apoptosis Jointly Mediate Cisatracurium Besylate-Induced Cell Injury. Int J Mol Sci. 2016;17:515 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:300; 图 2g
  • 免疫印迹; 小鼠; 1:2000; 图 2c
Son S, Cha M, Choi H, Kang S, Choi H, Lee M, et al. Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease. Autophagy. 2016;12:784-800 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 4
Peng Y, Kim M, Hullinger R, O Riordan K, Burger C, Pehar M, et al. Improved proteostasis in the secretory pathway rescues Alzheimer's disease in the mouse. Brain. 2016;139:937-52 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 e3
Ketel K, Krauss M, Nicot A, Puchkov D, Wieffer M, Müller R, et al. A phosphoinositide conversion mechanism for exit from endosomes. Nature. 2016;529:408-12 pubmed 出版商
  • 免疫细胞化学; 人类; 1:10; 图 2e
Kharaziha P, Chioureas D, Baltatzis G, Fonseca P, Rodriguez P, Gogvadze V, et al. Sorafenib-induced defective autophagy promotes cell death by necroptosis. Oncotarget. 2015;6:37066-82 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2b
Colecchia D, Rossi M, Sasdelli F, Sanzone S, Strambi A, Chiariello M. MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation. Autophagy. 2015;11:1790-802 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 1
Moreau K, Ghislat G, Hochfeld W, Renna M, Zavodszky E, Runwal G, et al. Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy. Nat Commun. 2015;6:8045 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s6b
Hirst J, Edgar J, Esteves T, Darios F, Madeo M, Chang J, et al. Loss of AP-5 results in accumulation of aberrant endolysosomes: defining a new type of lysosomal storage disease. Hum Mol Genet. 2015;24:4984-96 pubmed 出版商
  • 免疫印迹; 人类; 图 1a, 1b
  • 免疫印迹; 小鼠; 图 1f, 1g
Luo T, Fu J, Xu A, Su B, Ren Y, Li N, et al. PSMD10/gankyrin induces autophagy to promote tumor progression through cytoplasmic interaction with ATG7 and nuclear transactivation of ATG7 expression. Autophagy. 2016;12:1355-71 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
  • 免疫印迹; 人类; 图 1
Brandstaetter H, Kishi Itakura C, Tumbarello D, Manstein D, Buss F. Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion. Autophagy. 2014;10:2310-23 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200
Bejarano E, Yuste A, Patel B, Stout R, Spray D, Cuervo A. Connexins modulate autophagosome biogenesis. Nat Cell Biol. 2014;16:401-14 pubmed 出版商
  • 免疫细胞化学; 人类
Li W, Zhang X, Zhuang H, Chen H, Chen Y, Tian W, et al. MicroRNA-137 is a novel hypoxia-responsive microRNA that inhibits mitophagy via regulation of two mitophagy receptors FUNDC1 and NIX. J Biol Chem. 2014;289:10691-701 pubmed 出版商
  • 免疫印迹; 小鼠
Liu S, Hartleben B, Kretz O, Wiech T, Igarashi P, Mizushima N, et al. Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury. Autophagy. 2012;8:826-37 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000
Morris C, Stanton M, Manthey K, Oh K, Wagner K. A knockout of the Tsg101 gene leads to decreased expression of ErbB receptor tyrosine kinases and induction of autophagy prior to cell death. PLoS ONE. 2012;7:e34308 pubmed 出版商
Deitersen J, Berning L, Stuhldreier F, Ceccacci S, Schlütermann D, Friedrich A, et al. High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol. Cell Death Dis. 2021;12:560 pubmed 出版商
Arias Fuenzalida J, Jarazo J, Walter J, Gomez Giro G, Forster J, Krueger R, et al. Automated high-throughput high-content autophagy and mitophagy analysis platform. Sci Rep. 2019;9:9455 pubmed 出版商
Tian X, Zheng P, Zhou C, Wang X, Ma H, Ma W, et al. DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B. Autophagy. 2019;:1-14 pubmed 出版商
Colecchia D, Dapporto F, Tronnolone S, Salvini L, Chiariello M. MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process. J Biol Chem. 2018;293:15962-15976 pubmed 出版商
Yan M, Ye L, Yin S, Lu X, Liu X, Lu S, et al. Glycycoumarin protects mice against acetaminophen-induced liver injury predominantly via activating sustained autophagy. Br J Pharmacol. 2018;175:3747-3757 pubmed 出版商
Kanda R, Hiraike H, Wada Hiraike O, Ichinose T, Nagasaka K, Sasajima Y, et al. Expression of the glucagon-like peptide-1 receptor and its role in regulating autophagy in endometrial cancer. BMC Cancer. 2018;18:657 pubmed 出版商
Lassak A, Dean M, Wyczechowska D, Wilk A, Marrero L, Trillo Tinoco J, et al. Molecular and Structural Traits of Insulin Receptor Substrate 1/LC3 Nuclear Structures and Their Role in Autophagy Control and Tumor Cell Survival. Mol Cell Biol. 2018;38: pubmed 出版商
Newton T, Allison R, Edgar J, Lumb J, Rodger C, Manna P, et al. Mechanistic basis of an epistatic interaction reducing age at onset in hereditary spastic paraplegia. Brain. 2018;141:1286-1299 pubmed 出版商
Colecchia D, Stasi M, Leonardi M, Manganelli F, Nolano M, Veneziani B, et al. Alterations of autophagy in the peripheral neuropathy Charcot-Marie-Tooth type 2B. Autophagy. 2017;: pubmed 出版商
Chang M, Srinivasan K, Friedman B, Suto E, Modrusan Z, Lee W, et al. Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation. J Exp Med. 2017;214:2611-2628 pubmed 出版商
Aizawa S, Fujiwara Y, Contu V, Hase K, Takahashi M, Kikuchi H, et al. Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes. Autophagy. 2016;12:565-78 pubmed 出版商
公司信息
MBL International
15A Constitution Way Woburn, MA 01801
tech@mblintl.com
http://www.mblintl.com
800-200-5459 781-939-6964
公司总部: 美国