Hu T, Zhou Y, Lu J, Xia P, Chen Y, Cao X, et al. A novel rhamnoside derivative PL402 up-regulates matrix metalloproteinase 3/9 to promote Aβ degradation and alleviates Alzheimer's-like pathology. Aging (Albany NY). 2020;12:481-501 pubmed 出版商

Oleinik N, Kim J, Roth B, Selvam S, Gooz M, Johnson R, et al. Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress. Sci Adv. 2019;5:eaax1978 pubmed 出版商

ElMaghraby M, Andersen P, P hringer F, Hohmann U, Meixner K, Lendl T, et al. A Heterochromatin-Specific RNA Export Pathway Facilitates piRNA Production. Cell. 2019;178:964-979.e20 pubmed 出版商

Li Q, Youn J, Siu K, Murugesan P, Zhang Y, Cai H. Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction. Redox Biol. 2019;24:101185 pubmed 出版商

Kubli S, Bassi C, Roux C, Wakeham A, Göbl C, Zhou W, et al. AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer. Proc Natl Acad Sci U S A. 2019;116:3604-3613 pubmed 出版商

So C, Ramachandran S, Martin A. E3 Ubiquitin Ligases RNF20 and RNF40 Are Required for Double-Stranded Break (DSB) Repair: Evidence for Monoubiquitination of Histone H2B Lysine 120 as a Novel Axis of DSB Signaling and Repair. Mol Cell Biol. 2019;39: pubmed 出版商

Faliti C, Gualtierotti R, Rottoli E, Gerosa M, Perruzza L, Romagnani A, et al. P2X7 receptor restrains pathogenic Tfh cell generation in systemic lupus erythematosus. J Exp Med. 2019;216:317-336 pubmed 出版商

Gómez Fernández P, Urtasun A, Paton A, Paton J, Borrego F, Dersh D, et al. Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response. Front Immunol. 2018;9:2934 pubmed 出版商

Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, et al. LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. Nature. 2018;562:605-609 pubmed 出版商

Mollaoglu G, Jones A, Wait S, Mukhopadhyay A, Jeong S, Arya R, et al. The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment. Immunity. 2018;49:764-779.e9 pubmed 出版商

Hsu J, Xia W, Hsu Y, Chan L, Yu W, Cha J, et al. STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion. Nat Commun. 2018;9:1908 pubmed 出版商

Steinbuck M, Arakcheeva K, Winandy S. Novel TCR-Mediated Mechanisms of Notch Activation and Signaling. J Immunol. 2018;200:997-1007 pubmed 出版商

Yu R, Longo J, van Leeuwen J, Mullen P, Ba Alawi W, Haibe Kains B, et al. Statin-Induced Cancer Cell Death Can Be Mechanistically Uncoupled from Prenylation of RAS Family Proteins. Cancer Res. 2018;78:1347-1357 pubmed 出版商

Kage F, Winterhoff M, Dimchev V, Mueller J, Thalheim T, Freise A, et al. FMNL formins boost lamellipodial force generation. Nat Commun. 2017;8:14832 pubmed 出版商

Guo M, Tomoshige K, Meister M, Muley T, Fukazawa T, Tsuchiya T, et al. Gene signature driving invasive mucinous adenocarcinoma of the lung. EMBO Mol Med. 2017;9:462-481 pubmed 出版商

Tarr J, Visser T, Moon J, Hendesi H, Barbe M, Bradley J, et al. The pivotal role of CCN2 in mammalian palatogenesis. J Cell Commun Signal. 2017;11:25-37 pubmed 出版商

Dourlen P, Fernandez Gomez F, Dupont C, Grenier Boley B, Bellenguez C, Obriot H, et al. Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology. Mol Psychiatry. 2017;22:874-883 pubmed 出版商

Park S, Yoon S, Kim H, Kim K. 90K Glycoprotein Promotes Degradation of Mutant ?-Catenin Lacking the ISGylation or Phosphorylation Sites in the N-terminus. Neoplasia. 2016;18:618-625 pubmed 出版商

Zhang S, Wang P, Ren L, Hu C, Bi J. Protective effect of melatonin on soluble A?1-42-induced memory impairment, astrogliosis, and synaptic dysfunction via the Musashi1/Notch1/Hes1 signaling pathway in the rat hippocampus. Alzheimers Res Ther. 2016;8:40 pubmed 出版商

Lee H, Noh H, Mun J, Gu C, Sever S, Park S. Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis. Nat Commun. 2016;7:12799 pubmed 出版商

Mair B, Konopka T, Kerzendorfer C, Sleiman K, Salic S, Serra V, et al. Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity. PLoS Genet. 2016;12:e1006279 pubmed 出版商

Lee M, Tsai K, Hsu J, Shin S, Wu J, Yeh J. Liraglutide prevents and reverses monocrotaline-induced pulmonary arterial hypertension by suppressing ET-1 and enhancing eNOS/sGC/PKG pathways. Sci Rep. 2016;6:31788 pubmed 出版商

Park Y, Nam H, Do M, Lee J. The p90 ribosomal S6 kinase 2 specifically affects mitotic progression by regulating the basal level, distribution and stability of mitotic spindles. Exp Mol Med. 2016;48:e250 pubmed 出版商

Fong C, Mazo G, Das T, Goodman J, Kim M, O Rourke B, et al. 53BP1 and USP28 mediate p53-dependent cell cycle arrest in response to centrosome loss and prolonged mitosis. elife. 2016;5: pubmed 出版商

Talar B, Gajos Michniewicz A, Talar M, Chouaib S, Czyz M. Pentoxifylline Inhibits WNT Signalling in ?-Cateninhigh Patient-Derived Melanoma Cell Populations. PLoS ONE. 2016;11:e0158275 pubmed 出版商

Liu R, Moss B. Opposing Roles of Double-Stranded RNA Effector Pathways and Viral Defense Proteins Revealed with CRISPR-Cas9 Knockout Cell Lines and Vaccinia Virus Mutants. J Virol. 2016;90:7864-79 pubmed 出版商

Gui L, Liu B, Lv G. Hypoxia induces autophagy in cardiomyocytes via a hypoxia-inducible factor 1-dependent mechanism. Exp Ther Med. 2016;11:2233-2239 pubmed

Poirier S, Hamouda H, Villeneuve L, Demers A, Mayer G. Trafficking Dynamics of PCSK9-Induced LDLR Degradation: Focus on Human PCSK9 Mutations and C-Terminal Domain. PLoS ONE. 2016;11:e0157230 pubmed 出版商

Bento C, Ashkenazi A, Jimenez Sanchez M, Rubinsztein D. The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway. Nat Commun. 2016;7:11803 pubmed 出版商

Hintermair C, Voß K, Forné I, Heidemann M, Flatley A, Kremmer E, et al. Specific threonine-4 phosphorylation and function of RNA polymerase II CTD during M phase progression. Sci Rep. 2016;6:27401 pubmed 出版商

Hain K, Colin D, Rastogi S, Allan L, Clarke P. Prolonged mitotic arrest induces a caspase-dependent DNA damage response at telomeres that determines cell survival. Sci Rep. 2016;6:26766 pubmed 出版商

Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka I. A dual molecular analogue tuner for dissecting protein function in mammalian cells. Nat Commun. 2016;7:11742 pubmed 出版商

Marin V, Stornaiuolo A, Piovan C, Corna S, Bossi S, Pema M, et al. RD-MolPack technology for the constitutive production of self-inactivating lentiviral vectors pseudotyped with the nontoxic RD114-TR envelope. Mol Ther Methods Clin Dev. 2016;3:16033 pubmed 出版商

Syam N, Chatel S, Ozhathil L, Sottas V, Rougier J, Baruteau A, et al. Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block. J Am Heart Assoc. 2016;5: pubmed 出版商

Ashino T, Yamamoto M, Numazawa S. Nrf2/Keap1 system regulates vascular smooth muscle cell apoptosis for vascular homeostasis: role in neointimal formation after vascular injury. Sci Rep. 2016;6:26291 pubmed 出版商

Chan E, Shetty M, Sajikumar S, Chen C, Soong T, Wong B. ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing Aβ impairment of insulin signaling in an Alzheimer's disease mouse model. Sci Rep. 2016;6:26119 pubmed 出版商

Pethő Z, Tanner M, Tajhya R, Huq R, Laragione T, Panyi G, et al. Different expression of ? subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes. Arthritis Res Ther. 2016;18:103 pubmed 出版商

Seo J, Singh N, Ottesen E, Sivanesan S, Shishimorova M, Singh R. Oxidative Stress Triggers Body-Wide Skipping of Multiple Exons of the Spinal Muscular Atrophy Gene. PLoS ONE. 2016;11:e0154390 pubmed 出版商

Onyango D, Howard S, Neherin K, Yanez D, Stark J. Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination. Nucleic Acids Res. 2016;44:5702-16 pubmed 出版商

Albarrán L, Lopez J, Amor N, Martin Cano F, Berna Erro A, Smani T, et al. Dynamic interaction of SARAF with STIM1 and Orai1 to modulate store-operated calcium entry. Sci Rep. 2016;6:24452 pubmed 出版商

Toral Ojeda I, Aldanondo G, Lasa Elgarresta J, Lasa Fernández H, Fernandez Torron R, Lopez de Munain A, et al. Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle. Expert Rev Mol Med. 2016;18:e7 pubmed 出版商

Richmond B, Brucker R, Han W, Du R, Zhang Y, Cheng D, et al. Airway bacteria drive a progressive COPD-like phenotype in mice with polymeric immunoglobulin receptor deficiency. Nat Commun. 2016;7:11240 pubmed 出版商

Wilmington S, Matouschek A. An Inducible System for Rapid Degradation of Specific Cellular Proteins Using Proteasome Adaptors. PLoS ONE. 2016;11:e0152679 pubmed 出版商

Yu J, Berga S, Johnston MacAnanny E, Sidell N, Bagchi I, Bagchi M, et al. Endometrial Stromal Decidualization Responds Reversibly to Hormone Stimulation and Withdrawal. Endocrinology. 2016;157:2432-46 pubmed 出版商

Ziegler C, Eisenhauer P, Bruce E, Weir M, King B, Klaus J, et al. The Lymphocytic Choriomeningitis Virus Matrix Protein PPXY Late Domain Drives the Production of Defective Interfering Particles. PLoS Pathog. 2016;12:e1005501 pubmed 出版商

Park S, Yun Y, Lim J, Kim M, Kim S, Kim J, et al. Stabilin-2 modulates the efficiency of myoblast fusion during myogenic differentiation and muscle regeneration. Nat Commun. 2016;7:10871 pubmed 出版商

He H, Deng K, Siddiq M, Pyie A, Mellado W, Hannila S, et al. Cyclic AMP and Polyamines Overcome Inhibition by Myelin-Associated Glycoprotein through eIF5A-Mediated Increases in p35 Expression and Activation of Cdk5. J Neurosci. 2016;36:3079-91 pubmed 出版商

Gurdziel K, Vogt K, Walton K, Schneider G, Gumucio D. Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016;245:614-26 pubmed 出版商

Tepper S, Jeschke J, Böttcher K, Schmidt A, Davari K, Müller P, et al. PARP activation promotes nuclear AID accumulation in lymphoma cells. Oncotarget. 2016;7:13197-208 pubmed 出版商

Mackenzie K, Carroll P, Lettice L, TarnauskaitÄ— Å, Reddy K, Dix F, et al. Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response. EMBO J. 2016;35:831-44 pubmed 出版商

Gawron D, Ndah E, Gevaert K, Van Damme P. Positional proteomics reveals differences in N-terminal proteoform stability. Mol Syst Biol. 2016;12:858 pubmed 出版商

Morales Hernández A, González Rico F, Román A, Rico Leo E, Alvarez Barrientos A, Sánchez L, et al. Alu retrotransposons promote differentiation of human carcinoma cells through the aryl hydrocarbon receptor. Nucleic Acids Res. 2016;44:4665-83 pubmed 出版商

Delmas E, Jah N, Pirou C, Bouleau S, Le Floch N, Vayssière J, et al. FGF1 C-terminal domain and phosphorylation regulate intracrine FGF1 signaling for its neurotrophic and anti-apoptotic activities. Cell Death Dis. 2016;7:e2079 pubmed 出版商

Wu X, Fleming A, Ricketts T, Pavel M, Virgin H, Menzies F, et al. Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis. Nat Commun. 2016;7:10533 pubmed 出版商

Kwon D, Eom G, Ko J, Shin S, Joung H, Choe N, et al. MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification. Nat Commun. 2016;7:10492 pubmed 出版商

Ottesen E, Howell M, Singh N, Seo J, Whitley E, Singh R. Severe impairment of male reproductive organ development in a low SMN expressing mouse model of spinal muscular atrophy. Sci Rep. 2016;6:20193 pubmed 出版商

Dorris E, Blackshields G, Sommerville G, Alhashemi M, Dias A, McEneaney V, et al. Pluripotency markers are differentially induced by MEK inhibition in thyroid and melanoma BRAFV600E cell lines. Cancer Biol Ther. 2016;17:526-42 pubmed 出版商

Button R, Vincent J, Strang C, Luo S. Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget. 2016;7:5157-75 pubmed 出版商

Crawley S, Weck M, Grega Larson N, Shifrin D, Tyska M. ANKS4B Is Essential for Intermicrovillar Adhesion Complex Formation. Dev Cell. 2016;36:190-200 pubmed 出版商

Kuhn P, Colombo A, Schusser B, Dreymueller D, Wetzel S, Schepers U, et al. Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function. elife. 2016;5: pubmed 出版商

Thomassen M, Gunnarsson T, Christensen P, Pavlovic D, Shattock M, Bangsbo J. Intensive training and reduced volume increases muscle FXYD1 expression and phosphorylation at rest and during exercise in athletes. Am J Physiol Regul Integr Comp Physiol. 2016;310:R659-69 pubmed 出版商

Du Y, Yamaguchi H, Wei Y, Hsu J, Wang H, Hsu Y, et al. Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors. Nat Med. 2016;22:194-201 pubmed 出版商

Berge T, Leikfoss I, Brorson I, Bos S, Page C, Gustavsen M, et al. The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells. Genes Immun. 2016;17:118-27 pubmed 出版商

Mysore R, Zhou Y, Sädevirta S, Savolainen Peltonen H, Nidhina Haridas P, Soronen J, et al. MicroRNA-192* impairs adipocyte triglyceride storage. Biochim Biophys Acta. 2016;1861:342-51 pubmed 出版商

Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy. 2016;12:410-23 pubmed 出版商

Nishio M, Sugimachi K, Goto H, Wang J, Morikawa T, Miyachi Y, et al. Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice. Proc Natl Acad Sci U S A. 2016;113:E71-80 pubmed 出版商

Lagarrigue S, Lopez Mejia I, Denechaud P, Escoté X, Castillo Armengol J, Jimenez V, et al. CDK4 is an essential insulin effector in adipocytes. J Clin Invest. 2016;126:335-48 pubmed 出版商

Müller Schiffmann A, Herring A, Abdel Hafiz L, Chepkova A, Schäble S, Wedel D, et al. Amyloid-β dimers in the absence of plaque pathology impair learning and synaptic plasticity. Brain. 2016;139:509-25 pubmed 出版商

Dewaele M, Tabaglio T, Willekens K, Bezzi M, Teo S, Low D, et al. Antisense oligonucleotide-mediated MDM4 exon 6 skipping impairs tumor growth. J Clin Invest. 2016;126:68-84 pubmed 出版商

Harley M, Murina O, Leitch A, Higgs M, Bicknell L, Yigit G, et al. TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism. Nat Genet. 2016;48:36-43 pubmed 出版商

Yu Z, Huang Y, Shieh S. Requirement for human Mps1/TTK in oxidative DNA damage repair and cell survival through MDM2 phosphorylation. Nucleic Acids Res. 2016;44:1133-50 pubmed 出版商

Mohr M, Thomassen M, Girard O, Racinais S, Nybo L. Muscle variables of importance for physiological performance in competitive football. Eur J Appl Physiol. 2016;116:251-62 pubmed 出版商

Perotti V, Baldassari P, Molla A, Vegetti C, Bersani I, Maurichi A, et al. NFATc2 is an intrinsic regulator of melanoma dedifferentiation. Oncogene. 2016;35:2862-72 pubmed 出版商

Jacobs R, Lundby A, Fenk S, Gehrig S, Siebenmann C, Flück D, et al. Twenty-eight days of exposure to 3454 m increases mitochondrial volume density in human skeletal muscle. J Physiol. 2016;594:1151-66 pubmed 出版商

Thi Kim Ly B, Chi H. Effects of green tea epigallocatechin-3-gallate on transcription factors regulating expression of FLT3. J BUON. 2020;25:549-553 pubmed

Nakashima K, Ishida A. Regulation of Autophagy in Chick Skeletal Muscle: Effect of mTOR Inhibition. J Poult Sci. 2020;57:77-83 pubmed 出版商

Mendez Dorantes C, Tsai L, Jahanshir E, Lopezcolorado F, Stark J. BLM has Contrary Effects on Repeat-Mediated Deletions, based on the Distance of DNA DSBs to a Repeat and Repeat Divergence. Cell Rep. 2020;30:1342-1357.e4 pubmed 出版商

Mao L, Wang J. Upregulation of AMPA receptor GluA1 phosphorylation by blocking adenosine A1 receptors in the male rat forebrain. Brain Behav. 2020;10:e01543 pubmed 出版商

Brunner J, Vulliard L, Hofmann M, Kieler M, Lercher A, Vogel A, et al. Environmental arginine controls multinuclear giant cell metabolism and formation. Nat Commun. 2020;11:431 pubmed 出版商

Minderjahn J, Schmidt A, Fuchs A, Schill R, Raithel J, Babina M, et al. Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1. Nat Commun. 2020;11:402 pubmed 出版商

Tapia R, Kralicek S, Hecht G. Enteropathogenic Escherichia coli (EPEC) Recruitment of PAR Polarity Protein Atypical PKCζ to Pedestals and Cell-Cell Contacts Precedes Disruption of Tight Junctions in Intestinal Epithelial Cells. Int J Mol Sci. 2020;21: pubmed 出版商

Rosenbaum S, Knecht M, Mollaee M, Zhong Z, Erkes D, McCue P, et al. FOXD3 Regulates VISTA Expression in Melanoma. Cell Rep. 2020;30:510-524.e6 pubmed 出版商

Ciotti S, Iuliano L, Cefalù S, Comelli M, Mavelli I, Di Giorgio E, et al. GSK3β is a key regulator of the ROS-dependent necrotic death induced by the quinone DMNQ. Cell Death Dis. 2020;11:2 pubmed 出版商

Minami S, Yokota N, Kawahara H. BAG6 contributes to glucose uptake by supporting the cell surface translocation of the glucose transporter GLUT4. Biol Open. 2020;9: pubmed 出版商

Srinivasan V, Bruelle C, Scifo E, Pham D, Soliymani R, Lalowski M, et al. Dynamic Interaction of USP14 with the Chaperone HSC70 Mediates Crosstalk between the Proteasome, ER Signaling, and Autophagy. iScience. 2020;23:100790 pubmed 出版商

Hwang K, Kyaw Y, Kang H, Seong M, Cheong J. Mitochondrial dysfunction stimulates HBV gene expression through lipogenic transcription factor activation. Virus Res. 2020;277:197842 pubmed 出版商

Leiphrakpam P, Lazenby A, Chowdhury S, Smith L, Mathiesen M, Brattain M, et al. Prognostic and therapeutic implications of NHERF1 expression and regulation in colorectal cancer. J Surg Oncol. 2020;121:547-560 pubmed 出版商

Petrus P, Lecoutre S, Dollet L, Wiel C, Sulen A, Gao H, et al. Glutamine Links Obesity to Inflammation in Human White Adipose Tissue. Cell Metab. 2020;31:375-390.e11 pubmed 出版商

Tanaka H, Kaneko N, Sakagami H, Matsuya T, Hiramoto M, Yamanaka Y, et al. Naquotinib exerts antitumor activity in activated B-cell-like diffuse large B-cell lymphoma. Leuk Res. 2020;88:106286 pubmed 出版商

Sasani A, Hornig S, Grzybowski R, Cordts K, Hanff E, Tsikas D, et al. Muscle phenotype of AGAT- and GAMT-deficient mice after simvastatin exposure. Amino Acids. 2020;52:73-85 pubmed 出版商

Roberts S, Evans T, Yang Y, Fu Y, Button R, Sipthorpe R, et al. Bim contributes to the progression of Huntington's disease-associated phenotypes. Hum Mol Genet. 2020;29:216-227 pubmed 出版商

Sinitski D, Grüner K, Brandhofer M, Kontos C, Winkler P, Reinstädler A, et al. Cross-kingdom mimicry of the receptor signaling and leukocyte recruitment activity of a human cytokine by its plant orthologs. J Biol Chem. 2020;295:850-867 pubmed 出版商

Bella P, Farini A, Banfi S, Parolini D, Tonna N, Meregalli M, et al. Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy. EMBO Mol Med. 2020;12:e11019 pubmed 出版商

Samaranayake G, Troccoli C, Zhang L, Huynh M, Jayaraj C, Ji D, et al. The Existence of MTH1-independent 8-oxodGTPase Activity in Cancer Cells as a Compensatory Mechanism against On-target Effects of MTH1 Inhibitors. Mol Cancer Ther. 2020;19:432-446 pubmed 出版商

Young C, Gosselin M, Rumney R, Oksiejuk A, Chira N, Bożycki L, et al. Total Absence of Dystrophin Expression Exacerbates Ectopic Myofiber Calcification and Fibrosis and Alters Macrophage Infiltration Patterns. Am J Pathol. 2020;190:190-205 pubmed 出版商

Butler M, Armour E, Minnick J, Rossi M, Schock S, Berger S, et al. Effects of stress-induced increases of corticosterone on circulating triglyceride levels, biliverdin concentration, and heme oxygenase expression. Comp Biochem Physiol A Mol Integr Physiol. 2020;240:110608 pubmed 出版商

Sharma N, Haibara A, Katsurada K, Liu X, Patel K. Central angiotensin II-Protein inhibitor of neuronal nitric oxide synthase (PIN) axis contribute to neurogenic hypertension. Nitric Oxide. 2020;94:54-62 pubmed 出版商

Wu L, Awaji M, Saxena S, Varney M, Sharma B, Singh R. IL-17-CXC Chemokine Receptor 2 Axis Facilitates Breast Cancer Progression by Up-Regulating Neutrophil Recruitment. Am J Pathol. 2020;190:222-233 pubmed 出版商

Kittaka M, Yoshimoto T, Schlosser C, Rottapel R, Kajiya M, Kurihara H, et al. Alveolar Bone Protection by Targeting the SH3BP2-SYK Axis in Osteoclasts. J Bone Miner Res. 2020;35:382-395 pubmed 出版商

Wang L, Xu X, Jiang C, Ma G, Huang Y, Zhang H, et al. mTORC1-PGC1 axis regulates mitochondrial remodeling during reprogramming. FEBS J. 2020;287:108-121 pubmed 出版商

Nguyen P, Dagley L, Preaudet A, Lam N, Giam M, Fung K, et al. Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer. Cell Death Differ. 2020;27:742-757 pubmed 出版商

Ros G, Pegoraro S, De Angelis P, Sgarra R, Zucchelli S, Gustincich S, et al. HMGA2 Antisense Long Non-coding RNAs as New Players in the Regulation of HMGA2 Expression and Pancreatic Cancer Promotion. Front Oncol. 2019;9:1526 pubmed 出版商

Emperador S, Garrido Pérez N, Amezcua Gil J, Gaudó P, Andrés Sanz J, Yubero D, et al. Molecular Characterization of New FBXL4 Mutations in Patients With mtDNA Depletion Syndrome. Front Genet. 2019;10:1300 pubmed 出版商

Vassilieva E, Taylor D, Compans R. Combination of STING Pathway Agonist With Saponin Is an Effective Adjuvant in Immunosenescent Mice. Front Immunol. 2019;10:3006 pubmed 出版商

Ardid Ruiz A, Ibars M, Mena P, Del Rio D, Muguerza B, Arola L, et al. Resveratrol Treatment Enhances the Cellular Response to Leptin by Increasing OBRb Content in Palmitate-Induced Steatotic HepG2 Cells. Int J Mol Sci. 2019;20: pubmed 出版商

Morresi C, Cianfruglia L, Sartini D, Cecati M, Fumarola S, Emanuelli M, et al. Effect of High Glucose-Induced Oxidative Stress on Paraoxonase 2 Expression and Activity in Caco-2 Cells. Cells. 2019;8: pubmed 出版商

Huang Q, Hou J, Yang P, Yan J, Yu X, Zhuo Y, et al. Antiviral activity of mitoxantrone dihydrochloride against human herpes simplex virus mediated by suppression of the viral immediate early genes. BMC Microbiol. 2019;19:274 pubmed 出版商

Bianchi M, Crinelli R, Giacomini E, Carloni E, Radici L, Scarpa E, et al. A negative feedback mechanism links UBC gene expression to ubiquitin levels by affecting RNA splicing rather than transcription. Sci Rep. 2019;9:18556 pubmed 出版商

Pontecorvi P, Banki M, Zampieri C, Zalfa C, Azmoon P, Kounnas M, et al. Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines. J Neuroinflammation. 2019;16:257 pubmed 出版商

Han S, Wei R, Zhang X, Jiang N, Fan M, Huang J, et al. CPT1A/2-Mediated FAO Enhancement-A Metabolic Target in Radioresistant Breast Cancer. Front Oncol. 2019;9:1201 pubmed 出版商

De Toma I, Ortega M, Aloy P, Sabidó E, Dierssen M. DYRK1A Overexpression Alters Cognition and Neural-Related Proteomic Pathways in the Hippocampus That Are Rescued by Green Tea Extract and/or Environmental Enrichment. Front Mol Neurosci. 2019;12:272 pubmed 出版商

Ryu J, Kwon D, Choe N, Shin S, Jeong G, Lim Y, et al. Characterization of Circular RNAs in Vascular Smooth Muscle Cells with Vascular Calcification. Mol Ther Nucleic Acids. 2019;19:31-41 pubmed 出版商

De Snoo M, Friesen E, Zhang Y, Earnshaw R, Dorval G, Kapadia M, et al. Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death. Cell Death Dis. 2019;10:907 pubmed 出版商

Baquero J, Varriano S, Ordonez M, Kuczaj P, Murphy M, Aruggoda G, et al. Nuclear Tau, p53 and Pin1 Regulate PARN-Mediated Deadenylation and Gene Expression. Front Mol Neurosci. 2019;12:242 pubmed 出版商

D Eletto M, Risuglia A, Oliverio S, Mehdawy B, Nardacci R, Bordi M, et al. Modulation of autophagy by RTN-1C: role in autophagosome biogenesis. Cell Death Dis. 2019;10:868 pubmed 出版商

Toubiana S, Gagliardi M, Papa M, Manco R, Tzukerman M, Matarazzo M, et al. Persistent epigenetic memory impedes rescue of the telomeric phenotype in human ICF iPSCs following DNMT3B correction. elife. 2019;8: pubmed 出版商

van den Dries K, Nahidiazar L, Slotman J, Meddens M, Pandzic E, Joosten B, et al. Modular actin nano-architecture enables podosome protrusion and mechanosensing. Nat Commun. 2019;10:5171 pubmed 出版商

Chin C, Goh J, Srinivasan H, Liu K, Gowher A, Shanmugam R, et al. A human expression system based on HEK293 for the stable production of recombinant erythropoietin. Sci Rep. 2019;9:16768 pubmed 出版商

Unuma K, Yoshikawa A, Aki T, Uemura K. Increased circulating peroxiredoxin-4 in sepsis model rats involves secretion from hepatocytes and is mitigated by GYY4137. J Toxicol Pathol. 2019;32:305-310 pubmed 出版商

Szoka Ł, Isidorov V, Nazaruk J, Stocki M, Siergiejczyk L. Cytotoxicity of Triterpene Seco-Acids from Betula pubescens Buds. Molecules. 2019;24: pubmed 出版商

Ziegler C, Dang L, Eisenhauer P, Kelly J, King B, Klaus J, et al. NEDD4 family ubiquitin ligases associate with LCMV Z's PPXY domain and are required for virus budding, but not via direct ubiquitination of Z. PLoS Pathog. 2019;15:e1008100 pubmed 出版商

Randzavola L, Strege K, Juzans M, Asano Y, Stinchcombe J, Gawden Bone C, et al. Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity. J Clin Invest. 2019;129:5600-5614 pubmed 出版商

Zhang M, Ibáñez D, Fan W, Liu H, Zhong X, Wang X, et al. Generation of a PARK2 homozygous knockout induced pluripotent stem cell line (GIBHi002-A-1) with two common isoforms abolished. Stem Cell Res. 2019;41:101602 pubmed 出版商

Overå K, Garcia Garcia J, Bhujabal Z, Jain A, Øvervatn A, Larsen K, et al. TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1. J Cell Sci. 2019;132: pubmed 出版商

Moutal A, Shan Z, Miranda V, François Moutal L, Madura C, Khanna M, et al. Evaluation of edonerpic maleate as a CRMP2 inhibitor for pain relief. Channels (Austin). 2019;13:498-504 pubmed 出版商

Shiizaki K, Kido K, Mizuta Y. Insight into the relationship between aryl-hydrocarbon receptor and β-catenin in human colon cancer cells. PLoS ONE. 2019;14:e0224613 pubmed 出版商

Javaheri A, Bajpai G, Picataggi A, Mani S, Foroughi L, Evie H, et al. TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy. JCI Insight. 2019;4: pubmed 出版商

Jin R, Zhong W, Liu S, Li G. CD147 as a key mediator of the spleen inflammatory response in mice after focal cerebral ischemia. J Neuroinflammation. 2019;16:198 pubmed 出版商

Patel D, Ahmad F, Kambach D, Sun Q, Halim A, Kramp T, et al. LXRβ controls glioblastoma cell growth, lipid balance, and immune modulation independently of ABCA1. Sci Rep. 2019;9:15458 pubmed 出版商

Lo Dico A, Salvatore D, Martelli C, Ronchi D, Diceglie C, Lucignani G, et al. Intracellular Redox-Balance Involvement in Temozolomide Resistance-Related Molecular Mechanisms in Glioblastoma. Cells. 2019;8: pubmed 出版商

Sanchez Collado J, Lopez J, Jardin I, Camello P, Falcon D, Regodón S, et al. Adenylyl Cyclase Type 8 Overexpression Impairs Phosphorylation-Dependent Orai1 Inactivation and Promotes Migration in MDA-MB-231 Breast Cancer Cells. Cancers (Basel). 2019;11: pubmed 出版商

Zhai R, Dong X, Feng L, Li S, Hu Z. The Effect of Heat Stress on Autophagy and Apoptosis of Rumen, Abomasum, Duodenum, Liver and Kidney Cells in Calves. Animals (Basel). 2019;9: pubmed 出版商

Liu N, Wang Y, Sun Y, Ecsedy J, Sun J, Li X, et al. Inhibition of Aurora A enhances radiosensitivity in selected lung cancer cell lines. Respir Res. 2019;20:230 pubmed 出版商

Liu R, Olano L, Mirzakhanyan Y, Gershon P, Moss B. Vaccinia Virus Ankyrin-Repeat/F-Box Protein Targets Interferon-Induced IFITs for Proteasomal Degradation. Cell Rep. 2019;29:816-828.e6 pubmed 出版商

Sciarretta F, Fulci C, Palumbo C, Rotili D, Tentori L, Graziani G, et al. Effects of Glutathione Transferase-Targeting Nitrobenzoxadiazole Compounds in Relation to PD-L1 Status in Human Melanoma Cells. Chemotherapy. 2019;64:138-145 pubmed 出版商

Cabrita M, Renart L, Lau R, Pratt M. Intrinsically Disordered SRC-3/AIB1 Protein Undergoes Homeostatic Nuclear Extrusion by Nuclear Budding While Ectopic Expression Induces Nucleophagy. Cells. 2019;8: pubmed 出版商

Lin S, Huang C, Sun J, Bollt O, Wang X, Martine E, et al. The mitochondrial deoxyguanosine kinase is required for cancer cell stemness in lung adenocarcinoma. EMBO Mol Med. 2019;11:e10849 pubmed 出版商

Nishino H, Saito T, Wei R, Takano T, Tsutsumi K, Taniguchi M, et al. The LMTK1-TBC1D9B-Rab11A Cascade Regulates Dendritic Spine Formation via Endosome Trafficking. J Neurosci. 2019;39:9491-9502 pubmed 出版商

Nonaka K, Bando M, Sakamoto E, Inagaki Y, Naruishi K, Yumoto H, et al. 6-Shogaol Inhibits Advanced Glycation End-Products-Induced IL-6 and ICAM-1 Expression by Regulating Oxidative Responses in Human Gingival Fibroblasts. Molecules. 2019;24: pubmed 出版商

Ronchetti S, Pino M, Cordeiro G, Bollani S, Ricci A, Duvilanski B, et al. Soluble guanylyl cyclase α1 subunit is a key mediator of proliferation, survival, and migration in ECC-1 and HeLa cell lines. Sci Rep. 2019;9:14797 pubmed 出版商

Ji Cho M, Yoon S, Kim W, Park J, Lee J, Park J, et al. Oxidative stress-mediated TXNIP loss causes RPE dysfunction. Exp Mol Med. 2019;51:1-13 pubmed 出版商

Yamamoto S, Ishii T, Mikami R, Numata T, Shimizu S. Short TRPM2 prevents the targeting of full-length TRPM2 to the surface transmembrane by hijacking to ER associated degradation. Biochem Biophys Res Commun. 2019;520:520-525 pubmed 出版商

Party H, Dujarrier C, Hébert M, Lenoir S, Martinez de Lizarrondo S, Delepee R, et al. Plasminogen Activator Inhibitor-1 (PAI-1) deficiency predisposes to depression and resistance to treatments. Acta Neuropathol Commun. 2019;7:153 pubmed 出版商

Kim K, Kim J, Qiao J, Clark R, Powers C, Correa H, et al. Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma. Oncotarget. 2019;10:5645-5659 pubmed 出版商

Lauro C, Chece G, Monaco L, Antonangeli F, Peruzzi G, Rinaldo S, et al. Fractalkine Modulates Microglia Metabolism in Brain Ischemia. Front Cell Neurosci. 2019;13:414 pubmed 出版商

Gul N, Karlsson J, Tängemo C, Linsefors S, Tuyizere S, Perkins R, et al. The MTH1 inhibitor TH588 is a microtubule-modulating agent that eliminates cancer cells by activating the mitotic surveillance pathway. Sci Rep. 2019;9:14667 pubmed 出版商

Zhang X, Brachner A, Kukolj E, Slade D, Wang Y. SIRT2 deacetylates GRASP55 to facilitate post-mitotic Golgi assembly. J Cell Sci. 2019;132: pubmed 出版商

Bitetto G, Ronchi D, Bonato S, Pittaro A, Compagnoni G, Bordoni A, et al. Loss of the nucleoporin Aladin in central nervous system and fibroblasts of Allgrove Syndrome. Hum Mol Genet. 2019;28:3921-3927 pubmed 出版商

Oh S, Lee J, Kim H, Lee J, Han S, Bae J, et al. Ultrasonic Neuromodulation via Astrocytic TRPA1. Curr Biol. 2019;29:3386-3401.e8 pubmed 出版商

Lu H, Lu Y, Xie Y, Qiu S, Li X, Fan Z. Rational combination with PDK1 inhibition overcomes cetuximab resistance in head and neck squamous cell carcinoma. JCI Insight. 2019;4: pubmed 出版商

Wojnarowicz P, Lima e Silva R, Ohnaka M, Lee S, Chin Y, Kulukian A, et al. A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization. Cell Rep. 2019;29:62-75.e7 pubmed 出版商

Maiole F, Giachero S, Fossati S, Rocchi A, Zullo L. mTOR as a Marker of Exercise and Fatigue in Octopus vulgaris Arm. Front Physiol. 2019;10:1161 pubmed 出版商

Chhunchha B, Kubo E, Singh D. Sulforaphane-Induced Klf9/Prdx6 Axis Acts as a Molecular Switch to Control Redox Signaling and Determines Fate of Cells. Cells. 2019;8: pubmed 出版商

Grandon B, Rincheval Arnold A, Jah N, Corsi J, Araujo L, Glatigny S, et al. HLA-B27 alters BMP/TGFβ signalling in Drosophila, revealing putative pathogenic mechanism for spondyloarthritis. Ann Rheum Dis. 2019;78:1653-1662 pubmed 出版商

Pickar Oliver A, Black J, Lewis M, Mutchnick K, Klann T, Gilcrest K, et al. Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells. Nat Biotechnol. 2019;37:1493-1501 pubmed 出版商

Bakirtzi K, Man Law I, Fang K, Iliopoulos D, Pothoulakis C. MiR-21 in Substance P-induced exosomes promotes cell proliferation and migration in human colonic epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2019;317:G802-G810 pubmed 出版商

Bougen Zhukov N, Nouri Y, Godwin T, Taylor M, Hakkaart C, Single A, et al. Allosteric AKT Inhibitors Target Synthetic Lethal Vulnerabilities in E-Cadherin-Deficient Cells. Cancers (Basel). 2019;11: pubmed 出版商

Quiroga D, Miquet J, Gonzalez L, Sotelo A, Muñoz M, Geraldes P, et al. Mice lacking angiotensin type 2 receptor exhibit a sex-specific attenuation of insulin sensitivity. Mol Cell Endocrinol. 2019;498:110587 pubmed 出版商

Lee S, Quan K, Byun H, Park I, Kang K, Piao X, et al. Accelerated degradation of cFLIPL and sensitization of the TRAIL DISC-mediated apoptotic cascade by pinoresinol, a lignan isolated from Rubia philippinensis. Sci Rep. 2019;9:13505 pubmed 出版商

Bastón J, Cid F, Caviedes Vidal E, Chediack J. Daily expression of sodium-dependent glucose cotransporter-1 protein in jejunum during rat ontogeny. Anim Nutr. 2019;5:290-296 pubmed 出版商

Duarte S, Viedma Poyatos Á, Navarro Carrasco E, Martinez A, Pajares M, Perez Sala D. Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division. Nat Commun. 2019;10:4200 pubmed 出版商

Wu Q, Aroankins T, Cheng L, Fenton R. SUMOylation Landscape of Renal Cortical Collecting Duct Cells. J Proteome Res. 2019;18:3640-3648 pubmed 出版商

Funakoshi T, Furukawa M, Aki T, Uemura K. Repeated exposure of cocaine alters mitochondrial dynamics in mouse neuroblastoma Neuro2a. Neurotoxicology. 2019;75:70-77 pubmed 出版商

Bensellam M, Chan J, Lee K, Joglekar M, Hardikar A, Loudovaris T, et al. Phlda3 regulates beta cell survival during stress. Sci Rep. 2019;9:12827 pubmed 出版商

Gutiérrez Pérez I, Rowley M, Lyu X, Valadez Graham V, Vallejo D, Ballesta Illan E, et al. Ecdysone-Induced 3D Chromatin Reorganization Involves Active Enhancers Bound by Pipsqueak and Polycomb. Cell Rep. 2019;28:2715-2727.e5 pubmed 出版商

Magni M, Biancon G, Rizzitano S, Cavanè A, Paolizzi C, Dugo M, et al. Tyrosine kinase inhibition to improve anthracycline-based chemotherapy efficacy in T-cell lymphoma. Br J Cancer. 2019;121:567-577 pubmed 出版商

Shah J, Emery R, Lee B, Venkatasubramanian S, Simmons J, Brown M, et al. TOLLIP deficiency is associated with increased resistance to Legionella pneumophila pneumonia. Mucosal Immunol. 2019;12:1382-1390 pubmed 出版商

Neubauer J, Wang Z, Rougier J, Abriel H, Rieubland C, Bartholdi D, et al. Functional characterization of a novel SCN5A variant associated with long QT syndrome and sudden cardiac death. Int J Legal Med. 2019;133:1733-1742 pubmed 出版商

Jung S, Chung Y, Lee Y, Lee Y, Cho J, Shin E, et al. Buffering of cytosolic calcium plays a neuroprotective role by preserving the autophagy-lysosome pathway during MPP+-induced neuronal death. Cell Death Discov. 2019;5:130 pubmed 出版商

Khor B, Conway K, Omar A, Biton M, Haber A, Rogel N, et al. Distinct Tissue-Specific Roles for the Disease-Associated Autophagy Genes ATG16L2 and ATG16L1. J Immunol. 2019;203:1820-1829 pubmed 出版商

Hao Q, Gudapati V, Monsel A, Park J, Hu S, Kato H, et al. Mesenchymal Stem Cell-Derived Extracellular Vesicles Decrease Lung Injury in Mice. J Immunol. 2019;203:1961-1972 pubmed 出版商

Codrich M, Comelli M, Malfatti M, Mio C, Ayyildiz D, Zhang C, et al. Inhibition of APE1-endonuclease activity affects cell metabolism in colon cancer cells via a p53-dependent pathway. DNA Repair (Amst). 2019;82:102675 pubmed 出版商

Parvin S, Ramírez Labrada A, Aumann S, Lu X, Weich N, Santiago G, et al. LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL. Cancer Cell. 2019;36:237-249.e6 pubmed 出版商

Chen Y, Leng M, Gao Y, Zhan D, Choi J, Song L, et al. A Cross-Linking-Aided Immunoprecipitation/Mass Spectrometry Workflow Reveals Extensive Intracellular Trafficking in Time-Resolved, Signal-Dependent Epidermal Growth Factor Receptor Proteome. J Proteome Res. 2019;18:3715-3730 pubmed 出版商

Yang Y, Willis T, Button R, Strang C, Fu Y, Wen X, et al. Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response. Nat Commun. 2019;10:3759 pubmed 出版商

Singh V, Davidson A, Hume P, Koronakis V. Pathogenic Escherichia coli Hijacks GTPase-Activated p21-Activated Kinase for Actin Pedestal Formation. MBio. 2019;10: pubmed 出版商

Zappa F, Wilson C, Di Tullio G, Santoro M, Pucci P, Monti M, et al. The TRAPP complex mediates secretion arrest induced by stress granule assembly. EMBO J. 2019;38:e101704 pubmed 出版商

Zeng X, Carlin C. Adenovirus early region 3 RIDα protein limits NFκB signaling through stress-activated EGF receptors. PLoS Pathog. 2019;15:e1008017 pubmed 出版商

Talty A, Deegan S, Ljujic M, Mnich K, Naicker S, Quandt D, et al. Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β. Cell Death Dis. 2019;10:622 pubmed 出版商

Bowling J, Skolfield M, Riley W, Nolin A, Wolf L, Nelson D. Temporal integration of mitochondrial stress signals by the PINK1:Parkin pathway. BMC Mol Cell Biol. 2019;20:33 pubmed 出版商

Alessio N, Aprile D, Squillaro T, Di Bernardo G, Finicelli M, Melone M, et al. The senescence-associated secretory phenotype (SASP) from mesenchymal stromal cells impairs growth of immortalized prostate cells but has no effect on metastatic prostatic cancer cells. Aging (Albany NY). 2019;11:5817-5828 pubmed 出版商

Smolinska N, Kiezun M, Dobrzyn K, Rytelewska E, Kisielewska K, Gudelska M, et al. Expression of Chemerin and Its Receptors in the Porcine Hypothalamus and Plasma Chemerin Levels during the Oestrous Cycle and Early Pregnancy. Int J Mol Sci. 2019;20: pubmed 出版商

Spampinato S, Merlo S, Fagone E, Fruciano M, Barbagallo C, Kanda T, et al. Astrocytes Modify Migration of PBMCs Induced by β-Amyloid in a Blood-Brain Barrier in vitro Model. Front Cell Neurosci. 2019;13:337 pubmed 出版商

Schott M, Weller S, Schulze R, Krueger E, Drizyte Miller K, Casey C, et al. Lipid droplet size directs lipolysis and lipophagy catabolism in hepatocytes. J Cell Biol. 2019;218:3320-3335 pubmed 出版商

Nocita E, Del Giovane A, Tiberi M, Boccuni L, Fiorelli D, Sposato C, et al. EGFR/ErbB Inhibition Promotes OPC Maturation up to Axon Engagement by Co-Regulating PIP2 and MBP. Cells. 2019;8: pubmed 出版商

Su J, Zhu D, Huo Z, Gingold J, Ang Y, Tu J, et al. Genomic Integrity Safeguards Self-Renewal in Embryonic Stem Cells. Cell Rep. 2019;28:1400-1409.e4 pubmed 出版商

Heybrock S, Kanerva K, Meng Y, Ing C, Liang A, Xiong Z, et al. Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export. Nat Commun. 2019;10:3521 pubmed 出版商

Bittermann E, Abdelhamed Z, Liegel R, Menke C, Timms A, Beier D, et al. Differential requirements of tubulin genes in mammalian forebrain development. PLoS Genet. 2019;15:e1008243 pubmed 出版商

Kelso A, Lopezcolorado F, Bhargava R, Stark J. Distinct roles of RAD52 and POLQ in chromosomal break repair and replication stress response. PLoS Genet. 2019;15:e1008319 pubmed 出版商

Siew J, Chen H, Chen H, Chen H, Chen C, Soong B, et al. Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington's disease. Nat Commun. 2019;10:3473 pubmed 出版商

Dammert M, Brägelmann J, Olsen R, Böhm S, Monhasery N, Whitney C, et al. MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer. Nat Commun. 2019;10:3485 pubmed 出版商

Kral Pointner J, Schrottmaier W, Salzmann M, Mussbacher M, Schmidt G, Moser B, et al. Platelet PI3K Modulates Innate Leukocyte Extravasation during Acid-Induced Acute Lung Inflammation. Thromb Haemost. 2019;119:1642-1654 pubmed 出版商

Ke Y, Chan G, Stefanoska K, Au C, Bi M, Müller J, et al. CNS cell type-specific gene profiling of P301S tau transgenic mice identifies genes dysregulated by progressive tau accumulation. J Biol Chem. 2019;294:14149-14162 pubmed 出版商

Zhen A, Piao M, Kang K, Fernando P, Kang H, Koh Y, et al. Esculetin Prevents the Induction of Matrix Metalloproteinase-1 by Hydrogen Peroxide in Skin Keratinocytes. J Cancer Prev. 2019;24:123-128 pubmed 出版商

Lourenco C, Kalkat M, Houlahan K, De Melo J, Longo J, Done S, et al. Modelling the MYC-driven normal-to-tumour switch in breast cancer. Dis Model Mech. 2019;12: pubmed 出版商

Reichholf B, Herzog V, Fasching N, Manzenreither R, Sowemimo I, Ameres S. Time-Resolved Small RNA Sequencing Unravels the Molecular Principles of MicroRNA Homeostasis. Mol Cell. 2019;75:756-768.e7 pubmed 出版商

Poynter S, Herrington Krause S, Dewitte Orr S. Two DExD/H-box helicases, DDX3 and DHX9, identified in rainbow trout are able to bind dsRNA. Fish Shellfish Immunol. 2019;93:1056-1066 pubmed 出版商

Richardsen E, Andersen S, Al Saad S, Rakaee M, Nordby Y, Pedersen M, et al. Low Expression of miR-424-3p is Highly Correlated with Clinical Failure in Prostate Cancer. Sci Rep. 2019;9:10662 pubmed 出版商

Stacchiotti S, Zuco V, Tortoreto M, Cominetti D, Frezza A, Percio S, et al. Comparative Assessment of Antitumor Effects and Autophagy Induction as a Resistance Mechanism by Cytotoxics and EZH2 Inhibition in INI1-Negative Epithelioid Sarcoma Patient-Derived Xenograft. Cancers (Basel). 2019;11: pubmed 出版商

Gao L, Zhang Z, Lu J, Pei G. Mitochondria Are Dynamically Transferring Between Human Neural Cells and Alexander Disease-Associated GFAP Mutations Impair the Astrocytic Transfer. Front Cell Neurosci. 2019;13:316 pubmed 出版商

Casey M, Prakash A, Holian E, McGuire A, Kalinina O, Shalaby A, et al. Quantifying Argonaute 2 (Ago2) expression to stratify breast cancer. BMC Cancer. 2019;19:712 pubmed 出版商

Berardinelli F, Tanori M, Muoio D, Buccarelli M, Di Masi A, Leone S, et al. G-quadruplex ligand RHPS4 radiosensitizes glioblastoma xenograft in vivo through a differential targeting of bulky differentiated- and stem-cancer cells. J Exp Clin Cancer Res. 2019;38:311 pubmed 出版商

Zanin R, Pegoraro S, Ros G, Ciani Y, Piazza S, Bossi F, et al. HMGA1 promotes breast cancer angiogenesis supporting the stability, nuclear localization and transcriptional activity of FOXM1. J Exp Clin Cancer Res. 2019;38:313 pubmed 出版商

Bouillon J, Taylor S, Vargo C, Lange M, Zwicker L, Sukut S, et al. Beta-sarcoglycan-deficient muscular dystrophy presenting as chronic bronchopneumonia in a young cat. JFMS Open Rep. 2019;5:2055116919856457 pubmed 出版商

Dedoni S, Marras L, Olianas M, Ingianni A, Onali P. Downregulation of TrkB Expression and Signaling by Valproic Acid and Other Histone Deacetylase Inhibitors. J Pharmacol Exp Ther. 2019;370:490-503 pubmed 出版商

Gana C, Hanssen K, Yu D, Flemming C, Wheatley M, Conseil G, et al. MRP1 modulators synergize with buthionine sulfoximine to exploit collateral sensitivity and selectively kill MRP1-expressing cancer cells. Biochem Pharmacol. 2019;168:237-248 pubmed 出版商

Nash B, Tarn K, Irollo E, Luchetta J, Festa L, Halcrow P, et al. Morphine-Induced Modulation of Endolysosomal Iron Mediates Upregulation of Ferritin Heavy Chain in Cortical Neurons. Eneuro. 2019;6: pubmed 出版商

Torrisi S, Geraci F, Tropea M, Grasso M, Caruso G, Fidilio A, et al. Fluoxetine and Vortioxetine Reverse Depressive-Like Phenotype and Memory Deficits Induced by Aβ1-42 Oligomers in Mice: A Key Role of Transforming Growth Factor-β1. Front Pharmacol. 2019;10:693 pubmed 出版商

Rody W, Chamberlain C, Emory Carter A, McHugh K, Wallet S, Spicer V, et al. The proteome of extracellular vesicles released by clastic cells differs based on their substrate. PLoS ONE. 2019;14:e0219602 pubmed 出版商

Ponnusamy R, Khatri R, Correia P, Wood C, Mancini E, Farrell P, et al. Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity. PLoS Pathog. 2019;15:e1007458 pubmed 出版商

Jin H, Ko Y, Park S, Chang K, Kim H. 13-Ethylberberine Induces Apoptosis through the Mitochondria-Related Apoptotic Pathway in Radiotherapy-Resistant Breast Cancer Cells. Molecules. 2019;24: pubmed 出版商

Macías Pérez J, Aldaba Muruato L, Martínez Hernández S, Muñoz Ortega M, Pulido Ortega J, Ventura Juárez J. Curcumin Provides Hepatoprotection against Amoebic Liver Abscess Induced by Entamoeba histolytica in Hamster: Involvement of Nrf2/HO-1 and NF-κB/IL-1β Signaling Pathways. J Immunol Res. 2019;2019:7431652 pubmed 出版商

Bacigalupo M, Piazza V, Cicconi N, Carabias P, Bartke A, Fang Y, et al. Growth hormone upregulates the pro-tumorigenic galectin 1 in mouse liver. Endocr Connect. 2019;8:1108-1117 pubmed 出版商

Shen T, Hsu Y, Huang Y, Chen H, Hsieh C, Chen C. Licochalcone A Suppresses the Proliferation of Osteosarcoma Cells through Autophagy and ATM-Chk2 Activation. Molecules. 2019;24: pubmed 出版商

Dong X, Zhai R, Liu Z, Lin X, Wang Z, Hu Z. The Effect of Intravenous Infusions of Glutamine on Duodenal Cell Autophagy and Apoptosis in Early-Weaned Calves. Animals (Basel). 2019;9: pubmed 出版商

Gonçalves A, Margolis S, Quirino G, Mascarenhas D, Rauch I, Nichols R, et al. Gasdermin-D and Caspase-7 are the key Caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of Legionella pneumophila. PLoS Pathog. 2019;15:e1007886 pubmed 出版商

Locri F, Dal Monte M, Aronsson M, Cammalleri M, De Rosa M, Pavone V, et al. UPARANT is an effective antiangiogenic agent in a mouse model of rubeosis iridis. J Mol Med (Berl). 2019;97:1273-1283 pubmed 出版商

Marinkovic M, Fuoco C, Sacco F, Cerquone Perpetuini A, Giuliani G, Micarelli E, et al. Fibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH regulation of adipogenesis. Life Sci Alliance. 2019;2: pubmed 出版商

Bartels M, Weckbecker D, Kuhn P, Ryazanov S, Leonov A, Griesinger C, et al. Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression. Sci Rep. 2019;9:9100 pubmed 出版商

Hou J, Ju J, Zhang Z, Zhao C, Li Z, Zheng J, et al. Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasis. Cell Death Dis. 2019;10:493 pubmed 出版商

Josephy Hernández S, Pirvulescu I, Maira M, Aboulkassim T, Wong T, McKinney R, et al. Pharmacological interrogation of TrkA-mediated mechanisms in hippocampal-dependent memory consolidation. PLoS ONE. 2019;14:e0218036 pubmed 出版商

Kannan S, Aitken M, Herbrich S, Golfman L, Hall M, Mak D, et al. Anti-Leukemia Effects of Notch-Mediated Inhibition of Oncogenic PLK1 in B-Cell Acute Lymphoblastic Leukemia. Mol Cancer Ther. 2019;: pubmed 出版商

López Ureña D, Orozco Aguilar J, Chaves Madrigal Y, Ramírez Mata A, Villalobos Jimenez A, Ost S, et al. Toxin B Variants from Clostridium difficile Strains VPI 10463 and NAP1/027 Share Similar Substrate Profile and Cellular Intoxication Kinetics but Use Different Host Cell Entry Factors. Toxins (Basel). 2019;11: pubmed 出版商

Kummer S, Avinoam O, Kräusslich H. IFITM3 Clusters on Virus Containing Endosomes and Lysosomes Early in the Influenza A Infection of Human Airway Epithelial Cells. Viruses. 2019;11: pubmed 出版商

Ferrari M, Malardé V, Grassart A, Salavessa L, Nigro G, Descorps Declère S, et al. Shigella promotes major alteration of gut epithelial physiology and tissue invasion by shutting off host intracellular transport. Proc Natl Acad Sci U S A. 2019;: pubmed 出版商

Rankin C, Lokhandwala Z, Huang R, Pekow J, Pothoulakis C, Padua D. Linear and circular CDKN2B-AS1 expression is associated with Inflammatory Bowel Disease and participates in intestinal barrier formation. Life Sci. 2019;:116571 pubmed 出版商

Cousin M, Conboy E, Wang J, Lenz D, Schwab T, Williams M, et al. RINT1 Bi-allelic Variations Cause Infantile-Onset Recurrent Acute Liver Failure and Skeletal Abnormalities. Am J Hum Genet. 2019;: pubmed 出版商

Acosta G, Race N, Herr S, Fernandez J, Tang J, Rogers E, et al. Acrolein-mediated alpha-synuclein pathology involvement in the early post-injury pathogenesis of mild blast-induced Parkinsonian neurodegeneration. Mol Cell Neurosci. 2019;: pubmed 出版商

Huang K, Wu Y, Primeau T, Wang Y, Gao Y, McMichael J, et al. Regulated Phosphosignaling Associated with Breast Cancer Subtypes and Druggability. Mol Cell Proteomics. 2019;: pubmed 出版商

Qin L, Lin J, Xie X. CircRNA-9119 suppresses poly I:C induced inflammation in Leydig and Sertoli cells via TLR3 and RIG-I signal pathways. Mol Med. 2019;25:28 pubmed 出版商

Ng R, Manring H, Papoutsidakis N, Albertelli T, Tsai N, See C, et al. Patient mutations linked to arrhythmogenic cardiomyopathy enhance calpain-mediated desmoplakin degradation. JCI Insight. 2019;5: pubmed 出版商

Ito D, Zitouni S, Jana S, Duarte P, Surkont J, Carvalho Santos Z, et al. Pericentrin-mediated SAS-6 recruitment promotes centriole assembly. elife. 2019;8: pubmed 出版商

Kumanishi S, Yamanegi K, Nishiura H, Fujihara Y, Kobayashi K, Nakasho K, et al. Epigenetic modulators hydralazine and sodium valproate act synergistically in VEGI-mediated anti-angiogenesis and VEGF interference in human osteosarcoma and vascular endothelial cells. Int J Oncol. 2019;55:167-178 pubmed 出版商

Noah T, Knoop K, McDonald K, Gustafsson J, Waggoner L, Vanoni S, et al. IL-13-induced Intestinal secretory epithelial cell antigen passages are required for IgE-mediated food-induced anaphylaxis. J Allergy Clin Immunol. 2019;: pubmed 出版商

Yaron J, Chen H, Ambadapadi S, Zhang L, Tafoya A, Munk B, et al. Serp-2, a virus-derived apoptosis and inflammasome inhibitor, attenuates liver ischemia-reperfusion injury in mice. J Inflamm (Lond). 2019;16:12 pubmed 出版商

Chen Y, Li J, Jin L, Lei K, Liu H, Yang Y. Fibulin-5 contributes to colorectal cancer cell apoptosis via the ROS/MAPK and Akt signal pathways by downregulating transient receptor potential cation channel subfamily V member 1. J Cell Biochem. 2019;120:17838-17846 pubmed 出版商

Liu R, Mendez Rios J, Peng C, Xiao W, Weisberg A, Wyatt L, et al. SPI-1 is a missing host-range factor required for replication of the attenuated modified vaccinia Ankara (MVA) vaccine vector in human cells. PLoS Pathog. 2019;15:e1007710 pubmed 出版商

Ivankovic D, Drew J, Lesept F, White I, López Doménech G, Tooze S, et al. Axonal autophagosome maturation defect through failure of ATG9A sorting underpins pathology in AP-4 deficiency syndrome. Autophagy. 2019;:1-17 pubmed 出版商

Moshfegh C, Elkhatib S, Collins C, Kohl A, Case A. Autonomic and Redox Imbalance Correlates With T-Lymphocyte Inflammation in a Model of Chronic Social Defeat Stress. Front Behav Neurosci. 2019;13:103 pubmed 出版商

Chimienti G, Picca A, Fracasso F, Marzetti E, Calvani R, Leeuwenburgh C, et al. Differences in Liver TFAM Binding to mtDNA and mtDNA Damage between Aged and Extremely Aged Rats. Int J Mol Sci. 2019;20: pubmed 出版商

Verta R, Grange C, Gurrieri M, Borga S, Nardini P, Argenziano M, et al. Effect of Bilastine on Diabetic Nephropathy in DBA2/J Mice. Int J Mol Sci. 2019;20: pubmed 出版商

Tepper S, Mortusewicz O, Członka E, Bello A, Schmidt A, Jeschke J, et al. Restriction of AID activity and somatic hypermutation by PARP-1. Nucleic Acids Res. 2019;47:7418-7429 pubmed 出版商

Fazi B, Proserpio C, Galardi S, Annesi F, Cola M, Mangiola A, et al. The Expression of the Chemokine CXCL14 Correlates with Several Aggressive Aspects of Glioblastoma and Promotes Key Properties of Glioblastoma Cells. Int J Mol Sci. 2019;20: pubmed 出版商

Malvin N, Kern J, Liu T, Brody S, Stappenbeck T. Autophagy proteins are required for club cell structure and function in airways. Am J Physiol Lung Cell Mol Physiol. 2019;317:L259-L270 pubmed 出版商

Gómez Fernández P, Urtasun A, Astobiza I, Mena J, Alloza I, Vandenbroeck K. Pharmacological Targeting of the ER-Resident Chaperones GRP94 or Cyclophilin B Induces Secretion of IL-22 Binding Protein Isoform-1 (IL-22BPi1). Int J Mol Sci. 2019;20: pubmed 出版商

Perrier Groult E, Pérès E, Pasdeloup M, Gazzolo L, Duc Dodon M, Mallein Gerin F. Evaluation of the biocompatibility and stability of allogeneic tissue-engineered cartilage in humanized mice. PLoS ONE. 2019;14:e0217183 pubmed 出版商

Tencerova M, Frost M, Figeac F, Nielsen T, Ali D, Lauterlein J, et al. Obesity-Associated Hypermetabolism and Accelerated Senescence of Bone Marrow Stromal Stem Cells Suggest a Potential Mechanism for Bone Fragility. Cell Rep. 2019;27:2050-2062.e6 pubmed 出版商

Ilicheva N, Pochukalina G, Podgornaya O. Actin depolymerization disrupts karyosphere capsule integrity but not residual transcription in late oocytes of the grass frog Rana temporaria. J Cell Biochem. 2019;120:15057-15068 pubmed 出版商

Kishimoto Y, Zhu W, Hosoda W, Sen J, Mattson M. Chronic Mild Gut Inflammation Accelerates Brain Neuropathology and Motor Dysfunction in α-Synuclein Mutant Mice. Neuromolecular Med. 2019;: pubmed 出版商

Pavlova E, Shatunov A, Wartosch L, Moskvina A, Nikolaeva L, Bright N, et al. The lysosomal disease caused by mutant VPS33A. Hum Mol Genet. 2019;: pubmed 出版商

Caggiano C, Pieraccioli M, Panzeri V, Sette C, Bielli P. c-MYC empowers transcription and productive splicing of the oncogenic splicing factor Sam68 in cancer. Nucleic Acids Res. 2019;47:6160-6171 pubmed 出版商

Zhang Z, Amorosa L, Petrova A, Coyle S, Macor M, Nair M, et al. TLR4 counteracts BVRA signaling in human leukocytes via differential regulation of AMPK, mTORC1 and mTORC2. Sci Rep. 2019;9:7020 pubmed 出版商

Hoch L, Henriques S, Bruge C, Marsolier J, Benabides M, Bourg N, et al. Identification of thiostrepton as a pharmacological approach to rescue misfolded alpha-sarcoglycan mutant proteins from degradation. Sci Rep. 2019;9:6915 pubmed 出版商

Nagasu A, Mukai T, Iseki M, Kawahara K, Tsuji S, Nagasu H, et al. Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Faslpr Mice. Cells. 2019;8: pubmed 出版商

Walter D, Yates T, Ruiz Torres M, Kim Kiselak C, Gudiel A, Deshpande C, et al. RB constrains lineage fidelity and multiple stages of tumour progression and metastasis. Nature. 2019;569:423-427 pubmed 出版商

Ying J, Sato Y, Im E, Berg M, Bordi M, Darji S, et al. Lysosomal dysfunction in Down syndrome is APP-dependent and mediated by APP-βCTF (C99). J Neurosci. 2019;: pubmed 出版商

Maurel M, Obacz J, Avril T, Ding Y, Papadodima O, Treton X, et al. Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation. EMBO Mol Med. 2019;11: pubmed 出版商

Longo J, Mullen P, Yu R, van Leeuwen J, Masoomian M, Woon D, et al. An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer. Mol Metab. 2019;25:119-130 pubmed 出版商

Christiansen D, Macinnis M, Zacharewicz E, Xu H, Frankish B, Murphy R. A fast, reliable and sample-sparing method to identify fibre types of single muscle fibres. Sci Rep. 2019;9:6473 pubmed 出版商

Krishnamurthy A, Ytterberg A, Sun M, Sakuraba K, Steen J, Joshua V, et al. Citrullination Controls Dendritic Cell Transdifferentiation into Osteoclasts. J Immunol. 2019;202:3143-3150 pubmed 出版商

Krazinski B, Kiewisz J, Sliwinska Jewsiewicka A, Kowalczyk A, Grzegrzolka J, Godlewski J, et al. Altered Expression of DDR1 in Clear Cell Renal Cell Carcinoma Correlates With miR-199a/b-5p and Patients' Outcome. Cancer Genomics Proteomics. 2019;16:179-193 pubmed 出版商

Maier E, Attenberger F, Tiwari A, Lettau K, Rebholz S, Fehrenbacher B, et al. Dual Targeting of Y-Box Binding Protein-1 and Akt Inhibits Proliferation and Enhances the Chemosensitivity of Colorectal Cancer Cells. Cancers (Basel). 2019;11: pubmed 出版商

Chaurasia S, Kushwaha G, Kulkarni P, Mallick R, Latheef N, Mishra J, et al. Platelet HIF-2α promotes thrombogenicity through PAI-1 synthesis and extracellular vesicle release. Haematologica. 2019;: pubmed 出版商

Zhou M, Sareddy G, Li M, Liu J, Luo Y, Venkata P, et al. Estrogen receptor beta enhances chemotherapy response of GBM cells by down regulating DNA damage response pathways. Sci Rep. 2019;9:6124 pubmed 出版商

Orlando A, Chimienti G, Pesce V, Fracasso F, Lezza A, Russo F. An In Vitro Study on Mitochondrial Compensatory Response Induced by Gliadin Peptides in Caco-2 Cells. Int J Mol Sci. 2019;20: pubmed 出版商

Neubert P, Weichselbaum A, Reitinger C, Schatz V, Schröder A, Ferdinand J, et al. HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting. Autophagy. 2019;15:1899-1916 pubmed 出版商

Klebanovych A, Sladkova V, Sulimenko T, Vosecká V, Capek M, Dráberová E, et al. Regulation of Microtubule Nucleation in Mouse Bone Marrow-Derived Mast Cells by Protein Tyrosine Phosphatase SHP-1. Cells. 2019;8: pubmed 出版商

Williamson C, Donaldson J. Arf6, JIP3, and dynein shape and mediate macropinocytosis. Mol Biol Cell. 2019;30:1477-1489 pubmed 出版商

Klusóczki Á, Veréb Z, Vámos A, Fischer Posovszky P, Wabitsch M, Bacso Z, et al. Differentiating SGBS adipocytes respond to PPARγ stimulation, irisin and BMP7 by functional browning and beige characteristics. Sci Rep. 2019;9:5823 pubmed 出版商

Chen M, Du Y, Sun L, Hsu J, Wang Y, Gao Y, et al. H2O2 induces nuclear transport of the receptor tyrosine kinase c-MET in breast cancer cells via a membrane-bound retrograde trafficking mechanism. J Biol Chem. 2019;294:8516-8528 pubmed 出版商

Han Y, Chen M, Wang H, Hsu J, Li C, Chu Y, et al. Synergism of PARP inhibitor fluzoparib (HS10160) and MET inhibitor HS10241 in breast and ovarian cancer cells. Am J Cancer Res. 2019;9:608-618 pubmed

Lee S, Mayr C. Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation. Mol Cell. 2019;: pubmed 出版商

Sekhar K, Wang J, Freeman M, Kirschner A. Radiosensitization by enzalutamide for human prostate cancer is mediated through the DNA damage repair pathway. PLoS ONE. 2019;14:e0214670 pubmed 出版商

Fearnley G, Young K, Edgar J, Antrobus R, Hay I, Liang W, et al. The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell-cell adhesion. elife. 2019;8: pubmed 出版商

Iliev D, Lagos L, Thim H, Jørgensen S, Krasnov A, Jørgensen J. CpGs Induce Differentiation of Atlantic Salmon Mononuclear Phagocytes Into Cells With Dendritic Morphology and a Proinflammatory Transcriptional Profile but an Exhausted Allostimulatory Activity. Front Immunol. 2019;10:378 pubmed 出版商

Hayek I, Fischer F, Schulze Luehrmann J, Dettmer K, Sobotta K, Schatz V, et al. Limitation of TCA Cycle Intermediates Represents an Oxygen-Independent Nutritional Antibacterial Effector Mechanism of Macrophages. Cell Rep. 2019;26:3502-3510.e6 pubmed 出版商

Cox T, Gunther E, Brody A, Chiasseu M, Stoner A, Smith L, et al. Anti-PrPC antibody rescues cognition and synapses in transgenic alzheimer mice. Ann Clin Transl Neurol. 2019;6:554-574 pubmed 出版商

Hartsough E, Weiss M, Heilman S, Purwin T, Kugel C, Rosenbaum S, et al. CADM1 is a TWIST1-regulated suppressor of invasion and survival. Cell Death Dis. 2019;10:281 pubmed 出版商

Lieb S, Blaha Ostermann S, Kamper E, Rippka J, Schwarz C, Ehrenhöfer Wölfer K, et al. Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells. elife. 2019;8: pubmed 出版商

Bertolio R, Napoletano F, Mano M, Maurer Stroh S, Fantuz M, Zannini A, et al. Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism. Nat Commun. 2019;10:1326 pubmed 出版商

Liu Z, Mar K, Hanners N, Perelman S, Kanchwala M, Xing C, et al. A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB. Nature. 2019;: pubmed 出版商

Pierrot N, Ris L, Stancu I, Doshina A, Ribeiro F, Tyteca D, et al. Sex-regulated gene dosage effect of PPARα on synaptic plasticity. Life Sci Alliance. 2019;2: pubmed 出版商

Schwenzer H, Jühling F, Chu A, Pallett L, Baumert T, Maini M, et al. Oxidative Stress Triggers Selective tRNA Retrograde Transport in Human Cells during the Integrated Stress Response. Cell Rep. 2019;26:3416-3428.e5 pubmed 出版商

Akande O, Damle P, Pop M, Sherman N, Szomju B, Litovchick L, et al. DBC1 Regulates p53 Stability via Inhibition of CBP-Dependent p53 Polyubiquitination. Cell Rep. 2019;26:3323-3335.e4 pubmed 出版商

Zhang J, He J, Johnson J, Napolitano G, Ramadass M, Rahman F, et al. Cross-regulation of defective endolysosome trafficking and enhanced autophagy through TFEB in UNC13D deficiency. Autophagy. 2019;:1-19 pubmed 出版商

Rymut S, Lu B, Perez A, Corey D, Lamb K, Cotton C, et al. Acetyl-CoA carboxylase inhibition regulates microtubule dynamics and intracellular transport in cystic fibrosis epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2019;316:L1081-L1093 pubmed 出版商

Furuta M, Kikuchi H, Shoji T, Takashima Y, Kikuchi E, Kikuchi J, et al. DLL3 regulates the migration and invasion of small cell lung cancer by modulating Snail. Cancer Sci. 2019;110:1599-1608 pubmed 出版商

Moeglin E, Desplancq D, Conic S, Oulad Abdelghani M, Stoessel A, Chiper M, et al. Uniform Widespread Nuclear Phosphorylation of Histone H2AX Is an Indicator of Lethal DNA Replication Stress. Cancers (Basel). 2019;11: pubmed 出版商

Koshibu M, Mori Y, Saito T, Kushima H, Hiromura M, Terasaki M, et al. Antiatherogenic effects of liraglutide in hyperglycemic apolipoprotein E-null mice via AMP-activated protein kinase-independent mechanisms. Am J Physiol Endocrinol Metab. 2019;316:E895-E907 pubmed 出版商

Dehghan Harati M, Rodemann H, Toulany M. Nanog Signaling Mediates Radioresistance in ALDH-Positive Breast Cancer Cells. Int J Mol Sci. 2019;20: pubmed 出版商

Rivell A, Petralia R, Wang Y, Clawson E, Moehl K, Mattson M, et al. Sonic hedgehog expression in the postnatal brain. Biol Open. 2019;: pubmed 出版商

Ghersi J, Mahony C, Bertrand J. bif1, a new BMP signaling inhibitor, regulates embryonic hematopoiesis in the zebrafish. Development. 2019;: pubmed 出版商

Sohn S, Chay K. The ATP-dependent RNA helicase, DDX42 interacts with paxillin and regulates apoptosis and polarization of Ba/F3 cells. Anim Cells Syst (Seoul). 2019;23:1-9 pubmed 出版商

Rokavec M, Bouznad N, Hermeking H. Paracrine Induction of Epithelial-Mesenchymal Transition Between Colorectal Cancer Cells and its Suppression by a p53/miR-192/215/NID1 Axis. Cell Mol Gastroenterol Hepatol. 2019;7:783-802 pubmed 出版商

Mashimo M, Bu X, Aoyama K, Kato J, Ishiwata Endo H, Stevens L, et al. PARP1 inhibition alleviates injury in ARH3-deficient mice and human cells. JCI Insight. 2019;4: pubmed 出版商

Vallardi G, Allan L, Crozier L, Saurin A. Division of labour between PP2A-B56 isoforms at the centromere and kinetochore. elife. 2019;8: pubmed 出版商

Magistroni V, Mauri M, D Aliberti D, Mezzatesta C, Crespiatico I, Nava M, et al. De novo UBE2A mutations are recurrently acquired during chronic myeloid leukemia progression and interfere with myeloid differentiation pathways. Haematologica. 2019;: pubmed 出版商

Moshfegh C, Collins C, Gunda V, Vasanthakumar A, Cao J, Singh P, et al. Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4+ and CD8+ T-lymphocytes. Redox Biol. 2019;:101141 pubmed 出版商

Balkawade R, Chen C, Crowley M, Crossman D, Clapp W, Verlander J, et al. Podocyte-specific expression of Cre recombinase promotes glomerular basement membrane thickening. Am J Physiol Renal Physiol. 2019;316:F1026-F1040 pubmed 出版商

Owonikoko T, Zhang G, Lallani S, Chen Z, Martinson D, Khuri F, et al. Evaluation of preclinical efficacy of everolimus and pasireotide in thyroid cancer cell lines and xenograft models. PLoS ONE. 2019;14:e0206309 pubmed 出版商

Rivera Serrano E, Gonzalez Lopez O, Das A, Lemon S. Cellular entry and uncoating of naked and quasi-enveloped human hepatoviruses. elife. 2019;8: pubmed 出版商

Wu S, Zhang Y, De Luca F. The effect of a high-calorie diet on bone growth is mediated by the insulin receptor. Bone. 2019;122:166-175 pubmed 出版商

Brown B, Zhang Y, Westover D, Yan Y, Qiao H, Huang V, et al. On-target Resistance to the Mutant-Selective EGFR Inhibitor Osimertinib Can Develop in an Allele-Specific Manner Dependent on the Original EGFR-Activating Mutation. Clin Cancer Res. 2019;25:3341-3351 pubmed 出版商

Teissier T, Quersin V, Gnemmi V, Daroux M, Howsam M, Delguste F, et al. Knockout of receptor for advanced glycation end-products attenuates age-related renal lesions. Aging Cell. 2019;18:e12850 pubmed 出版商

Gonzales Aloy E, Connerty P, Salik B, Liu B, Woo A, Haber M, et al. miR-101 suppresses the development of MLL-rearranged acute myeloid leukemia. Haematologica. 2019;104:e296-e299 pubmed 出版商

Oliveira M, Lira R, Freire T, Luna C, Martins M, Almeida A, et al. Bone marrow mononuclear cell transplantation rescues the glomerular filtration barrier and epithelial cellular junctions in a renovascular hypertension model. Exp Physiol. 2019;104:740-754 pubmed 出版商

Preau S, Ambler M, Sigurtà A, Kleyman A, Dyson A, Hill N, et al. Protein recycling and limb muscle recovery after critical illness in slow- and fast-twitch limb muscle. Am J Physiol Regul Integr Comp Physiol. 2019;316:R584-R593 pubmed 出版商

Lian X, Bao C, Li X, Zhang X, Chen H, Jung Y, et al. Marek's Disease Virus Disables the ATR-Chk1 Pathway by Activating STAT3. J Virol. 2019;93: pubmed 出版商

Kiezun M, Dobrzyn K, Rytelewska E, Kisielewska K, Gudelska M, Szeszko K, et al. The effect of estrone and estradiol on the expression of the orexin/hypocretin system in the porcine uterus during early pregnancy. Domest Anim Endocrinol. 2019;68:11-24 pubmed 出版商

Tan C, Chin T, Tan C, Rovito H, Quek L, Oblong J, et al. Nicotinamide Metabolism Modulates the Proliferation/Differentiation Balance and Senescence of Human Primary Keratinocytes. J Invest Dermatol. 2019;: pubmed 出版商

Zhang J, He J, Johnson J, Rahman F, Gavathiotis E, Cuervo A, et al. Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells. Front Endocrinol (Lausanne). 2019;10:21 pubmed 出版商

Ma X, Mani K, Liu H, Kovacs A, Murphy J, Foroughi L, et al. Transcription Factor EB Activation Rescues Advanced αB-Crystallin Mutation-Induced Cardiomyopathy by Normalizing Desmin Localization. J Am Heart Assoc. 2019;8:e010866 pubmed 出版商

Moreno Moreno O, Torras Llort M, Azorín F. The E3-ligases SCFPpa and APC/CCdh1 co-operate to regulate CENP-ACID expression across the cell cycle. Nucleic Acids Res. 2019;47:3395-3406 pubmed 出版商

Sen R, Barman P, Kaja A, Ferdoush J, Lahudkar S, Roy A, et al. Distinct Functions of the Cap-Binding Complex in Stimulation of Nuclear mRNA Export. Mol Cell Biol. 2019;39: pubmed 出版商

Han M, Napier C, Frölich S, Teber E, Wong T, Noble J, et al. Synthetic lethality of cytolytic HSV-1 in cancer cells with ATRX and PML deficiency. J Cell Sci. 2019;132: pubmed 出版商

Sciarretta F, Fulci C, Palumbo C, Aquilano K, Pastore A, Iorio E, et al. Glutathione transferase P silencing promotes neuronal differentiation of retinal R28 cells. J Cell Physiol. 2019;: pubmed 出版商

James D, Kozol R, Kajiwara Y, Wahl A, Storrs E, Buxbaum J, et al. Intestinal dysmotility in a zebrafish (Danio rerio) shank3a;shank3b mutant model of autism. Mol Autism. 2019;10:3 pubmed 出版商

Horazna M, Janeckova L, Svec J, Babosova O, Hrckulak D, Vojtechova M, et al. Msx1 loss suppresses formation of the ectopic crypts developed in the Apc-deficient small intestinal epithelium. Sci Rep. 2019;9:1629 pubmed 出版商

Spychala A, Ruther U. FTO affects hippocampal function by regulation of BDNF processing. PLoS ONE. 2019;14:e0211937 pubmed 出版商

Pascut D, Sukowati C, Antoniali G, Mangiapane G, Burra S, Mascaretti L, et al. Serum AP-endonuclease 1 (sAPE1) as novel biomarker for hepatocellular carcinoma. Oncotarget. 2019;10:383-394 pubmed 出版商

El Bezawy R, Tinelli S, Tortoreto M, Doldi V, Zuco V, Folini M, et al. miR-205 enhances radiation sensitivity of prostate cancer cells by impairing DNA damage repair through PKCε and ZEB1 inhibition. J Exp Clin Cancer Res. 2019;38:51 pubmed 出版商

Solberg N, Melheim M, Strand M, Olsen P, Krauss S. MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition. Cancers (Basel). 2019;11: pubmed 出版商

Ottesen E, Luo D, Seo J, Singh N, Singh R. Human Survival Motor Neuron genes generate a vast repertoire of circular RNAs. Nucleic Acids Res. 2019;47:2884-2905 pubmed 出版商

Sołtysik K, Ohsaki Y, Tatematsu T, Cheng J, Fujimoto T. Nuclear lipid droplets derive from a lipoprotein precursor and regulate phosphatidylcholine synthesis. Nat Commun. 2019;10:473 pubmed 出版商

Stewart M, Lau P, Banks G, Bains R, Castroflorio E, Oliver P, et al. Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities. Dis Model Mech. 2019;12: pubmed 出版商

Smieszek A, Kornicka K, Sz apka Kosarzewska J, Androvic P, Valihrach L, Langerova L, et al. Metformin Increases Proliferative Activity and Viability of Multipotent Stromal Stem Cells Isolated from Adipose Tissue Derived from Horses with Equine Metabolic Syndrome. Cells. 2019;8: pubmed 出版商

Yoshiba T, Saga Y, Urabe M, Uchibori R, Matsubara S, Fujiwara H, et al. CRISPR/Cas9-mediated cervical cancer treatment targeting human papillomavirus E6. Oncol Lett. 2019;17:2197-2206 pubmed 出版商

Rocchi A, Moretti D, Lignani G, Colombo E, Scholz Starke J, Baldelli P, et al. Neurite-Enriched MicroRNA-218 Stimulates Translation of the GluA2 Subunit and Increases Excitatory Synaptic Strength. Mol Neurobiol. 2019;: pubmed 出版商

Paduch K, Debus A, Rai B, Schleicher U, Bogdan C. Resolution of Cutaneous Leishmaniasis and Persistence of Leishmania major in the Absence of Arginase 1. J Immunol. 2019;202:1453-1464 pubmed 出版商

Foidl B, Humpel C. Chronic treatment with five vascular risk factors causes cerebral amyloid angiopathy but no Alzheimer pathology in C57BL6 mice. Brain Behav Immun. 2019;78:52-64 pubmed 出版商

Kant S, Freytag B, Herzog A, Reich A, Merkel R, Hoffmann B, et al. Desmoglein 2 mutation provokes skeletal muscle actin expression and accumulation at intercalated discs in murine hearts. J Cell Sci. 2019;132: pubmed 出版商

Jiménez M, Urtasun R, Elizalde M, Azkona M, Latasa M, Uriarte I, et al. Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins. Nucleic Acids Res. 2019;47:3450-3466 pubmed 出版商

Zhao H, Zhuang Y, Li R, Liu Y, Mei Z, He Z, et al. Effects of different doses of X-ray irradiation on cell apoptosis, cell cycle, DNA damage repair and glycolysis in HeLa cells. Oncol Lett. 2019;17:42-54 pubmed 出版商

Hoffmann S, Orlando M, Andrzejak E, Bruns C, Trimbuch T, Rosenmund C, et al. Light-Activated ROS Production Induces Synaptic Autophagy. J Neurosci. 2019;39:2163-2183 pubmed 出版商

Borini Etichetti C, Di Benedetto C, Rossi C, Baglioni M, Bicciato S, Del Sal G, et al. Isoprenylcysteine carboxy methyltransferase (ICMT) is associated with tumor aggressiveness and its expression is controlled by the p53 tumor suppressor. J Biol Chem. 2019;294:5060-5073 pubmed 出版商

Wang X, Zhang M, Liu H. LncRNA17A regulates autophagy and apoptosis of SH-SY5Y cell line as an in vitro model for Alzheimer's disease. Biosci Biotechnol Biochem. 2019;83:609-621 pubmed 出版商

Darling A, Breydo L, Rivas E, Gebru N, Zheng D, Baker J, et al. Repeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteins. Int J Biol Macromol. 2019;127:136-145 pubmed 出版商

Anthony Jalin A, Jin R, Wang M, Li G. EPPS treatment attenuates traumatic brain injury in mice by reducing Aβ burden and ameliorating neuronal autophagic flux. Exp Neurol. 2019;314:20-33 pubmed 出版商

De Santi M, Baldelli G, Diotallevi A, Galluzzi L, Schiavano G, Brandi G. Metformin prevents cell tumorigenesis through autophagy-related cell death. Sci Rep. 2019;9:66 pubmed 出版商

Geisler F, Coch R, Richardson C, Goldberg M, Denecke B, Bossinger O, et al. The intestinal intermediate filament network responds to and protects against microbial insults and toxins. Development. 2019;: pubmed 出版商

Chen S, Zhang J, Chen J, Wang Y, Zhou S, Huang L, et al. RER1 enhances carcinogenesis and stemness of pancreatic cancer under hypoxic environment. J Exp Clin Cancer Res. 2019;38:15 pubmed 出版商

Hokonohara K, Nishida N, Miyoshi N, Takahashi H, Haraguchi N, Hata T, et al. Involvement of MAF1 homolog, negative regulator of RNA polymerase III in colorectal cancer progression. Int J Oncol. 2019;54:1001-1009 pubmed 出版商

Lee S, Salazar S, Cox T, Strittmatter S. Pyk2 Signaling through Graf1 and RhoA GTPase Is Required for Amyloid-β Oligomer-Triggered Synapse Loss. J Neurosci. 2019;39:1910-1929 pubmed 出版商

Yew W, Djukic N, Jayaseelan J, Walker F, Roos K, Chataway T, et al. Early treatment with minocycline following stroke in rats improves functional recovery and differentially modifies responses of peri-infarct microglia and astrocytes. J Neuroinflammation. 2019;16:6 pubmed 出版商

Aki T, Unuma K, Noritake K, Hirayama N, Funakoshi T, Uemura K. Formation of high molecular weight p62 by CORM-3. PLoS ONE. 2019;14:e0210474 pubmed 出版商

Bonnemaison M, Marks Nelson E, Boesen E. Sodium 4-phenylbutyrate treatment protects against renal injury in NZBWF1 mice. Clin Sci (Lond). 2019;: pubmed 出版商

Nichols J, Paschke P, Peak Chew S, Williams T, Tweedy L, Skehel M, et al. The Atypical MAP Kinase ErkB Transmits Distinct Chemotactic Signals through a Core Signaling Module. Dev Cell. 2019;48:491-505.e9 pubmed 出版商

Valdivieso A, Clauzure M, Massip Copiz M, Cancio C, Asensio C, Mori C, et al. Impairment of CFTR activity in cultured epithelial cells upregulates the expression and activity of LDH resulting in lactic acid hypersecretion. Cell Mol Life Sci. 2019;76:1579-1593 pubmed 出版商

Dong Q, Teng S, Wang Y, Qin F, Li Y, Ai L, et al. Sitagliptin protects the cognition function of the Alzheimer's disease mice through activating glucagon-like peptide-1 and BDNF-TrkB signalings. Neurosci Lett. 2019;696:184-190 pubmed 出版商

Liddiard K, Ruis B, Kan Y, Cleal K, Ashelford K, Hendrickson E, et al. DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase. Nucleic Acids Res. 2019;47:2402-2424 pubmed 出版商

Mocavini I, Pippa S, Licursi V, Paci P, Trisciuoglio D, Mannironi C, et al. JARID1B expression and its function in DNA damage repair are tightly regulated by miRNAs in breast cancer. Cancer Sci. 2019;110:1232-1243 pubmed 出版商

Moon S, Huang C, Houlihan S, Regunath K, Freed Pastor W, Morris J, et al. p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression. Cell. 2019;176:564-580.e19 pubmed 出版商

Khan I, Spencer Smith R, O Bryan J. Targeting the α4-α5 dimerization interface of K-RAS inhibits tumor formation in vivo. Oncogene. 2019;38:2984-2993 pubmed 出版商

Todaro F, Campolo F, Barrios F, Pellegrini M, Di Cesare S, Tessarollo L, et al. Regulation of Kit Expression in Early Mouse Embryos and ES Cells. Stem Cells. 2019;37:332-344 pubmed 出版商

Hald Ø, Olsen L, Gallo Oller G, Elfman L, Løkke C, Kogner P, et al. Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastoma. Oncogene. 2019;38:2800-2813 pubmed 出版商

Duval M, Hinge V, Snyder N, Kanyo R, Bratvold J, Pokrishevsky E, et al. Tryptophan 32 mediates SOD1 toxicity in a in vivo motor neuron model of ALS and is a promising target for small molecule therapeutics. Neurobiol Dis. 2019;124:297-310 pubmed 出版商

Salazar S, Cox T, Lee S, Brody A, Chyung A, Haas L, et al. Alzheimer's Disease Risk Factor Pyk2 Mediates Amyloid-β-Induced Synaptic Dysfunction and Loss. J Neurosci. 2019;39:758-772 pubmed 出版商

Park H, He A, Tan M, Johnson J, Dean J, Pietka T, et al. Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission. J Clin Invest. 2019;129:694-711 pubmed 出版商

Menotti M, Ambrogio C, Cheong T, Pighi C, Mota I, Cassel S, et al. Wiskott-Aldrich syndrome protein (WASP) is a tumor suppressor in T cell lymphoma. Nat Med. 2019;25:130-140 pubmed 出版商

Mirza N, Sowa A, Lautz K, Kufer T. NLRP10 Affects the Stability of Abin-1 To Control Inflammatory Responses. J Immunol. 2019;202:218-227 pubmed 出版商

Krazinski B, Kowalczyk A, Sliwinska Jewsiewicka A, Grzegrzolka J, Godlewski J, Kwiatkowski P, et al. IKBKB expression in clear cell renal cell carcinoma is associated with tumor grade and patient outcomes. Oncol Rep. 2019;41:1189-1197 pubmed 出版商

Heyn P, Logan C, Fluteau A, Challis R, Auchynnikava T, Martin C, et al. Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions. Nat Genet. 2019;51:96-105 pubmed 出版商

Puchalska P, Martin S, Huang X, Lengfeld J, Dániel B, Graham M, et al. Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis. Cell Metab. 2019;29:383-398.e7 pubmed 出版商

Miyazawa M, Bogdan A, Tsuji Y. Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2. Cell Chem Biol. 2019;26:85-97.e4 pubmed 出版商

Vigolo E, Markó L, Hinze C, Muller D, Schmidt Ullrich R, Schmidt Ott K. Canonical BMP signaling in tubular cells mediates recovery after acute kidney injury. Kidney Int. 2019;95:108-122 pubmed 出版商

Wilson R, Drake J, Cui D, Ritger M, Guan Y, Call J, et al. Voluntary running protects against neuromuscular dysfunction following hindlimb ischemia-reperfusion in mice. J Appl Physiol (1985). 2019;126:193-201 pubmed 出版商

Sun X, Zheng G, Li C, Liu C. Long non‑coding RNA Fer‑1‑like family member 4 suppresses hepatocellular carcinoma cell proliferation by regulating PTEN in vitro and in vivo. Mol Med Rep. 2019;19:685-692 pubmed 出版商

Osmanagic Myers S, Kiss A, Manakanatas C, Hamza O, Sedlmayer F, Szabo P, et al. Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse. J Clin Invest. 2019;129:531-545 pubmed 出版商

Dyck S, Kataria H, Akbari Kelachayeh K, Silver J, Karimi Abdolrezaee S. LAR and PTPσ receptors are negative regulators of oligodendrogenesis and oligodendrocyte integrity in spinal cord injury. Glia. 2019;67:125-145 pubmed 出版商

Fu Z, Hu J, Zhou L, Chen Y, Deng M, Liu X, et al. (Pro)renin receptor contributes to pregnancy-induced sodium-water retention in rats via activation of intrarenal RAAS and α-ENaC. Am J Physiol Renal Physiol. 2019;316:F530-F538 pubmed 出版商

Avola R, Graziano A, Pannuzzo G, Bonina F, Cardile V. Hydroxytyrosol from olive fruits prevents blue-light-induced damage in human keratinocytes and fibroblasts. J Cell Physiol. 2019;234:9065-9076 pubmed 出版商

Tsai J, Tsai S, Wu C. The chemopreventive isothiocyanate sulforaphane reduces anoikis resistance and anchorage-independent growth in non-small cell human lung cancer cells. Toxicol Appl Pharmacol. 2019;362:116-124 pubmed 出版商

Negussie S, Lymperopoulos A, Clark M. Role of βarrestin1 in AT1 R-mediated mitogen-activated protein kinase activation in Wistar and SHR brainstem astrocytes. J Neurochem. 2019;148:46-62 pubmed 出版商

Raimondi M, Cesselli D, Di Loreto C, La Marra F, Schneider C, Demarchi F. USP1 (ubiquitin specific peptidase 1) targets ULK1 and regulates its cellular compartmentalization and autophagy. Autophagy. 2019;15:613-630 pubmed 出版商

Sevillano J, Sánchez Alonso M, Zapatería B, Calderon M, Alcala M, Limones M, et al. Pleiotrophin deletion alters glucose homeostasis, energy metabolism and brown fat thermogenic function in mice. Diabetologia. 2019;62:123-135 pubmed 出版商

Shan J, Dudenhausen E, Kilberg M. Induction of early growth response gene 1 (EGR1) by endoplasmic reticulum stress is mediated by the extracellular regulated kinase (ERK) arm of the MAPK pathways. Biochim Biophys Acta Mol Cell Res. 2019;1866:371-381 pubmed 出版商

Sajek M, Janecki D, Smialek M, Ginter Matuszewska B, Spik A, Oczkowski S, et al. PUM1 and PUM2 exhibit different modes of regulation for SIAH1 that involve cooperativity with NANOS paralogues. Cell Mol Life Sci. 2019;76:147-161 pubmed 出版商

Son S, Park S, Lee H, Siddiqi F, Lee J, Menzies F, et al. Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A. Cell Metab. 2019;29:192-201.e7 pubmed 出版商

Wojtowicz A, Sitarz Głownia A, Szczesna M, Szychowski K. The Action of Di-(2-Ethylhexyl) Phthalate (DEHP) in Mouse Cerebral Cells Involves an Impairment in Aryl Hydrocarbon Receptor (AhR) Signaling. Neurotox Res. 2019;35:183-195 pubmed 出版商

Qiao Y, Bagheri H, Tang F, Badduke C, Martell S, Lewis S, et al. Exome sequencing identified a de novo mutation of PURA gene in a patient with familial Xp22.31 microduplication. Eur J Med Genet. 2019;62:103-108 pubmed 出版商

Lobato Márquez D, Krokowski S, Sirianni A, Larrouy Maumus G, Mostowy S. A requirement for septins and the autophagy receptor p62 in the proliferation of intracellular Shigella. Cytoskeleton (Hoboken). 2019;76:163-172 pubmed 出版商

Prieto G, Tong L, Smith E, Cotman C. TNFα and IL-1β but not IL-18 Suppresses Hippocampal Long-Term Potentiation Directly at the Synapse. Neurochem Res. 2019;44:49-60 pubmed 出版商

Mazucanti C, Kawamoto E, Mattson M, Scavone C, Camandola S. Activity-dependent neuronal Klotho enhances astrocytic aerobic glycolysis. J Cereb Blood Flow Metab. 2019;39:1544-1556 pubmed 出版商

Jiang Y, Ji J. Expression of Nuclear Lamin Proteins in Endothelial Cells is Sensitive to Cell Passage and Fluid Shear Stress. Cell Mol Bioeng. 2018;11:53-64 pubmed 出版商

Hentilä J, Nissinen T, Korkmaz A, Lensu S, Silvennoinen M, Pasternack A, et al. Activin Receptor Ligand Blocking and Cancer Have Distinct Effects on Protein and Redox Homeostasis in Skeletal Muscle and Liver. Front Physiol. 2018;9:1917 pubmed 出版商

Al Azzaz J, Rieu A, Aires V, Delmas D, Chluba J, Winckler P, et al. Resveratrol-Induced Xenophagy Promotes Intracellular Bacteria Clearance in Intestinal Epithelial Cells and Macrophages. Front Immunol. 2018;9:3149 pubmed 出版商

Ngo G, Hyatt S, Grimstead J, Jones R, HENDRICKSON E, Pepper C, et al. PARP inhibition prevents escape from a telomere-driven crisis and inhibits cell immortalisation. Oncotarget. 2018;9:37549-37563 pubmed 出版商

Nishijima H, Miki Y, Ueno S, Tomiyama M. Zonisamide Enhances Motor Effects of Levodopa, Not of Apomorphine, in a Rat Model of Parkinson's Disease. Parkinsons Dis. 2018;2018:8626783 pubmed 出版商

Broestl L, Worden K, Moreno A, Davis E, Wang D, Garay B, et al. Ovarian Cycle Stages Modulate Alzheimer-Related Cognitive and Brain Network Alterations in Female Mice. Eneuro. 2018;5: pubmed 出版商

Silva R, Castilho B, Sattlegger E. A Rapid Extraction Method for mammalian cell cultures, suitable for quantitative immunoblotting analysis of proteins, including phosphorylated GCN2 and eIF2α. MethodsX. 2018;5:75-82 pubmed 出版商

May O, Merle N, Grunenwald A, Gnemmi V, Leon J, Payet C, et al. Heme Drives Susceptibility of Glomerular Endothelium to Complement Overactivation Due to Inefficient Upregulation of Heme Oxygenase-1. Front Immunol. 2018;9:3008 pubmed 出版商

Gliemann L, Rytter N, Piil P, Nilton J, Lind T, Nyberg M, et al. The Endothelial Mechanotransduction Protein Platelet Endothelial Cell Adhesion Molecule-1 Is Influenced by Aging and Exercise Training in Human Skeletal Muscle. Front Physiol. 2018;9:1807 pubmed 出版商

Bonamy C, Sechet E, Amiot A, Alam A, Mourez M, Fraisse L, et al. Expression of the human antimicrobial peptide β-defensin-1 is repressed by the EGFR-ERK-MYC axis in colonic epithelial cells. Sci Rep. 2018;8:18043 pubmed 出版商

Bardai F, Ordonez D, Bailey R, Hamm M, Lewis J, Feany M. Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics. PLoS Biol. 2018;16:e2006265 pubmed 出版商

Roether J, Bertels S, Oelschlaeger C, Bastmeyer M, Willenbacher N. Microstructure, local viscoelasticity and cell culture suitability of 3D hybrid HA/collagen scaffolds. PLoS ONE. 2018;13:e0207397 pubmed 出版商

Yu J, Moutal A, Dorame A, Bellampalli S, Chefdeville A, Kanazawa I, et al. Phosphorylated CRMP2 Regulates Spinal Nociceptive Neurotransmission. Mol Neurobiol. 2018;: pubmed 出版商

Izumi T, Imai J, Yamamoto J, Kawana Y, Endo A, Sugawara H, et al. Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation. Nat Commun. 2018;9:5300 pubmed 出版商

Bonnin E, Cabochette P, Filosa A, Jühlen R, Komatsuzaki S, Hezwani M, et al. Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence. PLoS Genet. 2018;14:e1007845 pubmed 出版商

Wang X, Pei G. Visualization of Alzheimer's Disease Related α-/β-/γ-Secretase Ternary Complex by Bimolecular Fluorescence Complementation Based Fluorescence Resonance Energy Transfer. Front Mol Neurosci. 2018;11:431 pubmed 出版商

Kwiatkowski S, Seliga A, Vertommen D, Terreri M, Ishikawa T, Grabowska I, et al. SETD3 protein is the actin-specific histidine N-methyltransferase. elife. 2018;7: pubmed 出版商

Jensen S, Potts G, Ready D, Patterson M. Specific MHC-I Peptides Are Induced Using PROTACs. Front Immunol. 2018;9:2697 pubmed 出版商

OhAinle M, Helms L, Vermeire J, Roesch F, Humes D, Basom R, et al. A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV. elife. 2018;7: pubmed 出版商

Chen Y, Jiang P, Chen H, Chen C, Wang Y, Chen Y, et al. Glucose intake hampers PKA-regulated HSP90 chaperone activity. elife. 2018;7: pubmed 出版商

Novo D, Heath N, Mitchell L, Caligiuri G, MacFarlane A, Reijmer D, et al. Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels. Nat Commun. 2018;9:5069 pubmed 出版商

Fog C, Zago P, Malini E, Solanko L, Peruzzo P, Bornaes C, et al. The heat shock protein amplifier arimoclomol improves refolding, maturation and lysosomal activity of glucocerebrosidase. EBioMedicine. 2018;38:142-153 pubmed 出版商

Albarrán L, Lopez J, Jardin I, Sanchez Collado J, Berna Erro A, Smani T, et al. EFHB is a Novel Cytosolic Ca2+ Sensor That Modulates STIM1-SARAF Interaction. Cell Physiol Biochem. 2018;51:1164-1178 pubmed 出版商

Palladino M, Fasano G, Patel D, Dugan C, London M. Effects of lipopolysaccharide-induced inflammation on hypoxia and inflammatory gene expression pathways of the rat testis. Basic Clin Androl. 2018;28:14 pubmed 出版商

Kubala M, Punj V, Placencio Hickok V, Fang H, Fernandez G, Sposto R, et al. Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer. Cell Rep. 2018;25:2177-2191.e7 pubmed 出版商

Wege A, Chittka D, Buchholz S, Klinkhammer Schalke M, Diermeier Daucher S, Zeman F, et al. HER4 expression in estrogen receptor-positive breast cancer is associated with decreased sensitivity to tamoxifen treatment and reduced overall survival of postmenopausal women. Breast Cancer Res. 2018;20:139 pubmed 出版商

Lucas S, Chen G, Aras S, Wang J. Serine catabolism is essential to maintain mitochondrial respiration in mammalian cells. Life Sci Alliance. 2018;1:e201800036 pubmed 出版商

Delcroix V, Mauduit O, Tessier N, Montillaud A, Lesluyes T, Ducret T, et al. The Role of the Anti-Aging Protein Klotho in IGF-1 Signaling and Reticular Calcium Leak: Impact on the Chemosensitivity of Dedifferentiated Liposarcomas. Cancers (Basel). 2018;10: pubmed 出版商

Ardid Ruiz A, Ibars M, Mena P, Del Rio D, Muguerza B, Bladé C, et al. Potential Involvement of Peripheral Leptin/STAT3 Signaling in the Effects of Resveratrol and Its Metabolites on Reducing Body Fat Accumulation. Nutrients. 2018;10: pubmed 出版商

Dunberry Poissant S, Gilbert K, Bouchard C, Baril F, Cardinal A, L Ecuyer S, et al. Fluid sparing and norepinephrine use in a rat model of resuscitated haemorrhagic shock: end-organ impact. Intensive Care Med Exp. 2018;6:47 pubmed 出版商

Kalkat M, Resetca D, Lourenco C, Chan P, Wei Y, Shiah Y, et al. MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis. Mol Cell. 2018;72:836-848.e7 pubmed 出版商

Chhunchha B, Singh P, Singh D, Kubo E. Ginkgolic Acid Rescues Lens Epithelial Cells from Injury Caused by Redox Regulated-Aberrant Sumoylation Signaling by Reviving Prdx6 and Sp1 Expression and Activities. Int J Mol Sci. 2018;19: pubmed 出版商

Li L, Li L, Li W, Chen T, Bin Zou -, Zhao L, et al. TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation. Nat Commun. 2018;9:4683 pubmed 出版商

Li X, Oh S, Song H, Shin S, Zhang B, Freeman W, et al. A potential common role of the Jumonji C domain-containing 1A histone demethylase and chromatin remodeler ATRX in promoting colon cancer. Oncol Lett. 2018;16:6652-6662 pubmed 出版商

Hulse M, Caruso L, Madzo J, Tan Y, Johnson S, Tempera I. Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1. PLoS Pathog. 2018;14:e1007394 pubmed 出版商

Murai S, Yamaguchi Y, Shirasaki Y, Yamagishi M, Shindo R, Hildebrand J, et al. A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs. Nat Commun. 2018;9:4457 pubmed 出版商

Obaid M, Udden S, Deb P, Shihabeddin N, Zaki M, Mandal S. LncRNA HOTAIR regulates lipopolysaccharide-induced cytokine expression and inflammatory response in macrophages. Sci Rep. 2018;8:15670 pubmed 出版商

Protasoni M, Kroon A, Taanman J. Mitochondria as oncotarget: a comparison between the tetracycline analogs doxycycline and COL-3. Oncotarget. 2018;9:33818-33831 pubmed 出版商

Nakamura S, Sato Y, Kobayashi T, Oike T, Kaneko Y, Miyamoto K, et al. Insulin-like growth factor-I is required to maintain muscle volume in adult mice. J Bone Miner Metab. 2018;: pubmed 出版商

Ceyzériat K, Ben Haim L, Denizot A, Pommier D, Matos M, Guillemaud O, et al. Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer's disease. Acta Neuropathol Commun. 2018;6:104 pubmed 出版商

Iida R, Ueki M, Yasuda T. Knockout of Mpv17-Like Protein (M-LPH) Gene in Human Hepatoma Cells Results in Impairment of mtDNA Integrity through Reduction of TFAM, OGG1, and LIG3 at the Protein Levels. Oxid Med Cell Longev. 2018;2018:6956414 pubmed 出版商

Chen Y, Su Y, Kung J. B Cell Development sans B Cell Receptor Responsiveness Due to Unfolded Protein Response-Triggered Mef2c Protein Degradation. J Immunol. 2018;201:2885-2898 pubmed 出版商

Ni S, Ren F, Xu M, Tan C, Weng W, Huang Z, et al. CTHRC1 overexpression predicts poor survival and enhances epithelial-mesenchymal transition in colorectal cancer. Cancer Med. 2018;7:5643-5654 pubmed 出版商

Strigli A, Raab C, Hessler S, Huth T, Schuldt A, Alzheimer C, et al. Doxorubicin induces caspase-mediated proteolysis of KV7.1. Commun Biol. 2018;1:155 pubmed 出版商

Karuppagounder S, Alin L, Chen Y, Brand D, Bourassa M, Dietrich K, et al. N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with prostaglandin E2 to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in mice. Ann Neurol. 2018;84:854-872 pubmed 出版商

Liu J, Xu D, Li J, Gao N, Liao C, Jing R, et al. The role of focal adhesion kinase in transforming growth factor-β2 induced migration of human lens epithelial cells. Int J Mol Med. 2018;42:3591-3601 pubmed 出版商

Sechet E, Telford E, Bonamy C, Sansonetti P, Sperandio B. Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3. Proc Natl Acad Sci U S A. 2018;115:E9869-E9878 pubmed 出版商

Chatterjee S, Cassel R, Schneider Anthony A, Merienne K, Cosquer B, Tzeplaeff L, et al. Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator. EMBO Mol Med. 2018;10: pubmed 出版商

Ilicheva N, Podgornaya O, Bogolyubov D, Pochukalina G. The karyosphere capsule in Rana temporaria oocytes contains structural and DNA-binding proteins. Nucleus. 2018;9:516-529 pubmed 出版商

Ko Y, Jin H, Lee J, Park S, Chang K, Kang K, et al. Radioresistant breast cancer cells exhibit increased resistance to chemotherapy and enhanced invasive properties due to cancer stem cells. Oncol Rep. 2018;40:3752-3762 pubmed 出版商

Iervolino A, De La Motte L, Petrillo F, Prosperi F, Alvino F, Schiano G, et al. Integrin Beta 1 Is Crucial for Urinary Concentrating Ability and Renal Medulla Architecture in Adult Mice. Front Physiol. 2018;9:1273 pubmed 出版商

Davies A, Itzhak D, Edgar J, Archuleta T, Hirst J, Jackson L, et al. AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A. Nat Commun. 2018;9:3958 pubmed 出版商

Bacman S, Kauppila J, Pereira C, Nissanka N, Miranda M, Pinto M, et al. MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation. Nat Med. 2018;24:1696-1700 pubmed 出版商

Qiu S, Wu Y, Lv X, Li X, Zhuo M, Koga K. Reduced synaptic function of Kainate receptors in the insular cortex of Fmr1 Knock-out mice. Mol Brain. 2018;11:54 pubmed 出版商

Moreno Marín N, Merino J, Alvarez Barrientos A, Patel D, Takahashi S, González Sancho J, et al. Aryl Hydrocarbon Receptor Promotes Liver Polyploidization and Inhibits PI3K, ERK, and Wnt/?-Catenin Signaling. iScience. 2018;4:44-63 pubmed 出版商

Cohen C, Corpet A, Roubille S, Maroui M, Poccardi N, Rousseau A, et al. Promyelocytic leukemia (PML) nuclear bodies (NBs) induce latent/quiescent HSV-1 genomes chromatinization through a PML NB/Histone H3.3/H3.3 Chaperone Axis. PLoS Pathog. 2018;14:e1007313 pubmed 出版商

Wagner A, Devarakonda S, Skidmore Z, Krysiak K, Ramu A, Trani L, et al. Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer. Nat Commun. 2018;9:3787 pubmed 出版商

Jardin I, Diez Bello R, Lopez J, Redondo P, Salido G, Smani T, et al. TRPC6 Channels Are Required for Proliferation, Migration and Invasion of Breast Cancer Cell Lines by Modulation of Orai1 and Orai3 Surface Exposure. Cancers (Basel). 2018;10: pubmed 出版商

Kim S, Min I, Park Y, Lee S, Kim S. Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK-mediated DR5 regulation in colorectal cancer. Int J Oncol. 2018;53:2789-2799 pubmed 出版商

Dhayat S, Traeger M, Rehkaemper J, Stroese A, Steinestel K, Wardelmann E, et al. Clinical Impact of Epithelial-to-Mesenchymal Transition Regulating MicroRNAs in Pancreatic Ductal Adenocarcinoma. Cancers (Basel). 2018;10: pubmed 出版商

Chhunchha B, Kubo E, Singh P, Singh D. Sumoylation-deficient Prdx6 repairs aberrant Sumoylation-mediated Sp1 dysregulation-dependent Prdx6 repression and cell injury in aging and oxidative stress. Aging (Albany NY). 2018;10:2284-2315 pubmed 出版商

Mylka V, Deckers J, Ratman D, De Cauwer L, Thommis J, De Rycke R, et al. The autophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages. Autophagy. 2018;14:2049-2064 pubmed 出版商

Vianello E, Zampieri S, Marcuzzo T, Tordini F, Bottin C, Dardis A, et al. Histone acetylation as a new mechanism for bilirubin-induced encephalopathy in the Gunn rat. Sci Rep. 2018;8:13690 pubmed 出版商

Janecki D, Sajek M, Smialek M, Kotecki M, Ginter Matuszewska B, Kuczynska B, et al. SPIN1 is a proto-oncogene and SPIN3 is a tumor suppressor in human seminoma. Oncotarget. 2018;9:32466-32477 pubmed 出版商

Dalal K, Morin H, Ban F, Shepherd A, Fernandez M, Tam K, et al. Small molecule-induced degradation of the full length and V7 truncated variant forms of human androgen receptor. Eur J Med Chem. 2018;157:1164-1173 pubmed 出版商

Ignatius M, Hayes M, Moore F, Tang Q, Garcia S, Blackburn P, et al. tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish. elife. 2018;7: pubmed 出版商

Pascual Serrano A, Bladé C, Suarez M, Arola Arnal A. Grape Seed Proanthocyanidins Improve White Adipose Tissue Expansion during Diet-Induced Obesity Development in Rats. Int J Mol Sci. 2018;19: pubmed 出版商

Arnoux I, Willam M, Griesche N, Krummeich J, Watari H, Offermann N, et al. Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease. elife. 2018;7: pubmed 出版商

Anfuso B, El Khobar K, Ie S, Avellini C, Radillo O, Raseni A, et al. Activation of hepatic stem cells compartment during hepatocarcinogenesis in a HBsAg HBV-transgenic mouse model. Sci Rep. 2018;8:13168 pubmed 出版商

Sanders S, Ma Z, Hughes J, Riscoe B, Gibson G, Watson A, et al. CRISPR/Cas9-mediated gene knockin in the hydroid Hydractinia symbiolongicarpus. BMC Genomics. 2018;19:649 pubmed 出版商

Chiku T, Hayashishita M, Saito T, Oka M, Shinno K, Ohtake Y, et al. S6K/p70S6K1 protects against tau-mediated neurodegeneration by decreasing the level of tau phosphorylated at Ser262 in a Drosophila model of tauopathy. Neurobiol Aging. 2018;71:255-264 pubmed 出版商

Ho S, Lin W. RNF144A sustains EGFR signaling to promote EGF-dependent cell proliferation. J Biol Chem. 2018;293:16307-16323 pubmed 出版商

Dingar D, Tu W, Resetca D, Lourenco C, Tamachi A, De Melo J, et al. MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability. Nat Commun. 2018;9:3502 pubmed 出版商

Lee S, Singh I, Tisdale S, Abdel Wahab O, Leslie C, Mayr C. Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia. Nature. 2018;561:127-131 pubmed 出版商

Akiyama H, Miller C, Ettinger C, Belkina A, Snyder Cappione J, Gummuluru S. HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction. Nat Commun. 2018;9:3450 pubmed 出版商

Fomin V, Richard P, Hoque M, Li C, Gu Z, Fissore O Leary M, et al. The C9ORF72 Gene, Implicated in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia, Encodes a Protein That Functions in Control of Endothelin and Glutamate Signaling. Mol Cell Biol. 2018;38: pubmed 出版商

Qi B, Han M. Microbial Siderophore Enterobactin Promotes Mitochondrial Iron Uptake and Development of the Host via Interaction with ATP Synthase. Cell. 2018;175:571-582.e11 pubmed 出版商

Hsu C, Huang Y, Hsieh C, Wu C, Shen T. JNK Inactivation Induces Polyploidy and Drug-Resistance in Coronarin D-Treated Osteosarcoma Cells. Molecules. 2018;23: pubmed 出版商

Lertsuwan J, Lertsuwan K, Sawasdichai A, Tasnawijitwong N, Lee K, Kitchen P, et al. CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism. Cancers (Basel). 2018;10: pubmed 出版商

Mehta M, Weinberg S, Steinert E, Chhiba K, Martinez C, Gao P, et al. Hexokinase 2 is dispensable for T cell-dependent immunity. Cancer Metab. 2018;6:10 pubmed 出版商

Endo Y, Shen Y, Youssef L, Mohan N, Wu W. T-DM1-resistant cells gain high invasive activity via EGFR and integrin cooperated pathways. MAbs. 2018;10:1003-1017 pubmed 出版商

Wang N, Zou C, Zhao S, Wang Y, Han C, Zheng Z. Fenofibrate Exerts Protective Effects in Diabetic Retinopathy via Inhibition of the ANGPTL3 Pathway. Invest Ophthalmol Vis Sci. 2018;59:4210-4217 pubmed 出版商

Planchon D, Rios Morris E, Genest M, Comunale F, Vacher S, Bieche I, et al. MT1-MMP targeting to endolysosomes is mediated by upregulation of flotillins. J Cell Sci. 2018;131: pubmed 出版商

Fu Z, Cao X, Yang Y, Song Z, Zhang J, Wang Z. Upregulation of FoxM1 by MnSOD Overexpression Contributes to Cancer Stem-Like Cell Characteristics in the Lung Cancer H460 Cell Line. Technol Cancer Res Treat. 2018;17:1533033818789635 pubmed 出版商

Hutter Schmid B, Humpel C. Primary mouse brain pericytes isolated from transgenic Alzheimer mice spontaneously differentiate into a CD11b+ microglial-like cell type in vitro. Exp Gerontol. 2018;112:30-37 pubmed 出版商

Ghosh S, Shang P, Terasaki H, Stepicheva N, Hose S, Yazdankhah M, et al. A Role for βA3/A1-Crystallin in Type 2 EMT of RPE Cells Occurring in Dry Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2018;59:AMD104-AMD113 pubmed 出版商

Dupret B, Volkel P, Follet P, Le Bourhis X, Angrand P. Combining genotypic and phenotypic analyses on single mutant zebrafish larvae. MethodsX. 2018;5:244-256 pubmed 出版商

Aiba Y, Harada K, Ito M, Suematsu T, Aishima S, Hitomi Y, et al. Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis. Sci Rep. 2018;8:11808 pubmed 出版商

Holterman C, Boisvert N, Thibodeau J, Kamto E, Novakovic M, Abdelrahman K, et al. Podocyte NADPH Oxidase 5 Promotes Renal Inflammation Regulated by the Toll-like Receptor Pathway. Antioxid Redox Signal. 2018;: pubmed 出版商

Aweida D, Rudesky I, Volodin A, Shimko E, Cohen S. GSK3-β promotes calpain-1-mediated desmin filament depolymerization and myofibril loss in atrophy. J Cell Biol. 2018;217:3698-3714 pubmed 出版商

Martin C, Sarlós K, Logan C, Thakur R, Parry D, Bizard A, et al. Mutations in TOP3A Cause a Bloom Syndrome-like Disorder. Am J Hum Genet. 2018;103:221-231 pubmed 出版商

Pavel M, Renna M, Park S, Menzies F, Ricketts T, Füllgrabe J, et al. Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis. Nat Commun. 2018;9:2961 pubmed 出版商

Garcia Gimeno M, Rodilla Ramirez P, Viana R, Salas Puig X, Brewer M, Gentry M, et al. A novel EPM2A mutation yields a slow progression form of Lafora disease. Epilepsy Res. 2018;145:169-177 pubmed 出版商

Storck S, Hartz A, Bernard J, Wolf A, Kachlmeier A, Mahringer A, et al. The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM. Brain Behav Immun. 2018;73:21-33 pubmed 出版商

Bobustuc G, Kassam A, Rovin R, Jeudy S, Smith J, Isley B, et al. MGMT inhibition in ER positive breast cancer leads to CDC2, TOP2A, AURKB, CDC20, KIF20A, Cyclin A2, Cyclin B2, Cyclin D1, ERα and Survivin inhibition and enhances response to temozolomide. Oncotarget. 2018;9:29727-29742 pubmed 出版商

Moor M, Haenzi B, Legrand F, Koesters R, Hynes N, Bonny O. Renal Memo1 Differentially Regulates the Expression of Vitamin D-Dependent Distal Renal Tubular Calcium Transporters. Front Physiol. 2018;9:874 pubmed 出版商

El Buri A, Adams D, Smith D, Tate R, Mullin M, Pyne S, et al. The sphingosine 1-phosphate receptor 2 is shed in exosomes from breast cancer cells and is N-terminally processed to a short constitutively active form that promotes extracellular signal regulated kinase activation and DNA synthesis in fibroblasts. Oncotarget. 2018;9:29453-29467 pubmed 出版商

Kikuchi H, Sakakibara Konishi J, Furuta M, Kikuchi E, Kikuchi J, Oizumi S, et al. Numb has distinct function in lung adenocarcinoma and squamous cell carcinoma. Oncotarget. 2018;9:29379-29391 pubmed 出版商

Zamaraev A, Kopeina G, Buchbinder J, Zhivotovsky B, Lavrik I. Caspase-2 is a negative regulator of necroptosis. Int J Biochem Cell Biol. 2018;102:101-108 pubmed 出版商

Wood C, Carvell T, Gunnell A, Ojeniyi O, Osborne C, West M. Enhancer Control of MicroRNA miR-155 Expression in Epstein-Barr Virus-Infected B Cells. J Virol. 2018;92: pubmed 出版商

Borin M, Saraceno C, Catania M, Lorenzetto E, Pontelli V, Paterlini A, et al. Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer's disease. Acta Neuropathol Commun. 2018;6:61 pubmed 出版商

Conlon E, Fagegaltier D, Agius P, Davis Porada J, Gregory J, Hubbard I, et al. Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism. elife. 2018;7: pubmed 出版商

Childress M, Himmelberg S, Chen H, Deng W, Davies M, Lovly C. ALK Fusion Partners Impact Response to ALK Inhibition: Differential Effects on Sensitivity, Cellular Phenotypes, and Biochemical Properties. Mol Cancer Res. 2018;16:1724-1736 pubmed 出版商

Rao A, LaBonne C. Histone deacetylase activity has an essential role in establishing and maintaining the vertebrate neural crest. Development. 2018;145: pubmed 出版商

Bianchi B, Smith P, Abriel H. The ion channel TRPM4 in murine experimental autoimmune encephalomyelitis and in a model of glutamate-induced neuronal degeneration. Mol Brain. 2018;11:41 pubmed 出版商

Gupta P, Uner O, Nayak S, Grant G, Kalb R. SAP97 regulates behavior and expression of schizophrenia risk enriched gene sets in mouse hippocampus. PLoS ONE. 2018;13:e0200477 pubmed 出版商

Allan L, Skowyra A, Rogers K, Zeller D, Clarke P. Atypical APC/C-dependent degradation of Mcl-1 provides an apoptotic timer during mitotic arrest. EMBO J. 2018;37: pubmed 出版商

Hoffmann C, Mao X, Brown Clay J, Moreau F, Al Absi A, Wurzer H, et al. Hypoxia promotes breast cancer cell invasion through HIF-1?-mediated up-regulation of the invadopodial actin bundling protein CSRP2. Sci Rep. 2018;8:10191 pubmed 出版商

Zimmermann M, Murina O, Reijns M, Agathanggelou A, Challis R, Tarnauskaitė Ž, et al. CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions. Nature. 2018;559:285-289 pubmed 出版商

Zabala A, Vázquez Villoldo N, Rissiek B, Gejo J, Martin A, Palomino A, et al. P2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitis. EMBO Mol Med. 2018;10: pubmed 出版商

Jung I, Kim Y, Yu H, Lee M, Kim S, Lee J. CRISPR/Cas9-Mediated Knockout of DGK Improves Antitumor Activities of Human T Cells. Cancer Res. 2018;78:4692-4703 pubmed 出版商

Bhargava R, Sandhu M, Muk S, Lee G, Vaidehi N, Stark J. C-NHEJ without indels is robust and requires synergistic function of distinct XLF domains. Nat Commun. 2018;9:2484 pubmed 出版商

Seong J, Kim N, Kim J, Lee W, Seo J, Yum M, et al. Side branching and luminal lineage commitment by ID2 in developing mammary glands. Development. 2018;145: pubmed 出版商

Colin D, Cottet Dumoulin D, Faivre A, Germain S, Triponez F, Serre Beinier V. Experimental Model of Human Malignant Mesothelioma in Athymic Mice. Int J Mol Sci. 2018;19: pubmed 出版商

Cruz V, Arner E, Wynne K, Scherer P, Brekken R. Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction. Mol Metab. 2018;16:139-149 pubmed 出版商

Eikesdal H, Becker L, Teng Y, Kizu A, Carstens J, Kanasaki K, et al. BMP7 Signaling in TGFBR2-Deficient Stromal Cells Provokes Epithelial Carcinogenesis. Mol Cancer Res. 2018;16:1568-1578 pubmed 出版商

Kimura A, Kitajima M, Nishida K, Serada S, Fujimoto M, Naka T, et al. NQO1 inhibits the TLR-dependent production of selective cytokines by promoting IκB-ζ degradation. J Exp Med. 2018;215:2197-2209 pubmed 出版商

Colineau L, Lambertz U, Fornes O, Wasserman W, Reiner N. c-Myc is a novel Leishmania virulence factor by proxy that targets the host miRNA system and is essential for survival in human macrophages. J Biol Chem. 2018;293:12805-12819 pubmed 出版商

Nacarelli T, Azar A, Altinok O, Orynbayeva Z, Sell C. Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts. GeroScience. 2018;: pubmed 出版商

Stewart S, Ashkenazi A, Williamson A, Rubinsztein D, Moreau K. Transbilayer phospholipid movement facilitates the translocation of annexin across membranes. J Cell Sci. 2018;131: pubmed 出版商

Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, de Tullio P, et al. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2018;558:605-609 pubmed 出版商

d Avignon D, Puchalska P, Ercal B, Chang Y, Martin S, Graham M, et al. Hepatic ketogenic insufficiency reprograms hepatic glycogen metabolism and the lipidome. JCI Insight. 2018;3: pubmed 出版商

Garcia E, Emerman M. Recurrent Loss of APOBEC3H Activity during Primate Evolution. J Virol. 2018;92: pubmed 出版商

Pallavicini G, Sgrò F, Garello F, Falcone M, Bitonto V, Berto G, et al. Inactivation of Citron Kinase Inhibits Medulloblastoma Progression by Inducing Apoptosis and Cell Senescence. Cancer Res. 2018;78:4599-4612 pubmed 出版商

Anusornvongchai T, Nangaku M, Jao T, Wu C, Ishimoto Y, Maekawa H, et al. Palmitate deranges erythropoietin production via transcription factor ATF4 activation of unfolded protein response. Kidney Int. 2018;94:536-550 pubmed 出版商

Dovey C, Diep J, Clarke B, Hale A, McNamara D, Guo H, et al. MLKL Requires the Inositol Phosphate Code to Execute Necroptosis. Mol Cell. 2018;70:936-948.e7 pubmed 出版商

Carr D, Lau R, Hnatykiw A, Ward G, Daneshmand M, Cabrita M, et al. cIAP2 Is an Independent Signaling and Survival Factor during Mammary Lactational Involution and Tumorigenesis. J Mammary Gland Biol Neoplasia. 2018;23:109-123 pubmed 出版商

Razidlo G, Burton K, McNiven M. Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42. J Biol Chem. 2018;293:11143-11153 pubmed 出版商

Gu H, Zhou B. Focal adhesion kinase promotes progression and predicts poor clinical outcomes in patients with osteosarcoma. Oncol Lett. 2018;15:6225-6232 pubmed 出版商

Mori Y, Kushima H, Koshibu M, Saito T, Hiromura M, Kohashi K, et al. Glucose-Dependent Insulinotropic Polypeptide Suppresses Peripheral Arterial Remodeling in Male Mice. Endocrinology. 2018;159:2717-2732 pubmed 出版商

Bai C, Zhang J, Shi T, Bai Y, Wu B, Du Z, et al. Association between 5-lipoxygenase expression, and malignant behaviors and poor prognosis in esophageal squamous cell carcinoma. Oncol Lett. 2018;15:9353-9360 pubmed 出版商

Nichols M, Pavlov E, Robertson G. Tamoxifen-induced knockdown of the mitochondrial calcium uniporter in Thy1-expressing neurons protects mice from hypoxic/ischemic brain injury. Cell Death Dis. 2018;9:606 pubmed 出版商

Bigas J, Sevilla L, Carceller E, Boix J, Perez P. Epidermal glucocorticoid and mineralocorticoid receptors act cooperatively to regulate epidermal development and counteract skin inflammation. Cell Death Dis. 2018;9:588 pubmed 出版商

Cerquone Perpetuini A, Re Cecconi A, Chiappa M, Martinelli G, Fuoco C, Desiderio G, et al. Group I Paks support muscle regeneration and counteract cancer-associated muscle atrophy. J Cachexia Sarcopenia Muscle. 2018;9:727-746 pubmed 出版商

Dorraji S, Hovd A, Kanapathippillai P, Bakland G, Eilertsen G, Figenschau S, et al. Mesenchymal stem cells and T cells in the formation of Tertiary Lymphoid Structures in Lupus Nephritis. Sci Rep. 2018;8:7861 pubmed 出版商

Albrecht L, Ploper D, Tejeda Muñoz N, De Robertis E. Arginine methylation is required for canonical Wnt signaling and endolysosomal trafficking. Proc Natl Acad Sci U S A. 2018;115:E5317-E5325 pubmed 出版商

Mitchell K, Barreyro L, Todorova T, Taylor S, Antony Debré I, Narayanagari S, et al. IL1RAP potentiates multiple oncogenic signaling pathways in AML. J Exp Med. 2018;215:1709-1727 pubmed 出版商

Bauer D, Tellier M, Martínez Alonso M, Nojima T, Proudfoot N, Murphy S, et al. Influenza Virus Mounts a Two-Pronged Attack on Host RNA Polymerase II Transcription. Cell Rep. 2018;23:2119-2129.e3 pubmed 出版商

Hoffmann N, Weise S, Marinaro F, Vogel T, De Pietri Tonelli D. DGCR8 Promotes Neural Progenitor Expansion and Represses Neurogenesis in the Mouse Embryonic Neocortex. Front Neurosci. 2018;12:281 pubmed 出版商

Ugras S, Daniels M, Fazelinia H, Gould N, Yocum A, Luk K, et al. Induction of the Immunoproteasome Subunit Lmp7 Links Proteostasis and Immunity in α-Synuclein Aggregation Disorders. EBioMedicine. 2018;31:307-319 pubmed 出版商

Merlo S, Spampinato S, Beneventano M, Sortino M. The contribution of microglia to early synaptic compensatory responses that precede β-amyloid-induced neuronal death. Sci Rep. 2018;8:7297 pubmed 出版商

Sedlmayer F, Hell D, Müller M, Ausländer D, Fussenegger M. Designer cells programming quorum-sensing interference with microbes. Nat Commun. 2018;9:1822 pubmed 出版商

Cheng Y, Shieh S. Deubiquitinating enzyme USP3 controls CHK1 chromatin association and activation. Proc Natl Acad Sci U S A. 2018;115:5546-5551 pubmed 出版商

Grossi V, Forte G, Sanese P, Peserico A, Tezil T, Lepore Signorile M, et al. The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer. Nucleic Acids Res. 2018;46:5587-5600 pubmed 出版商

Ribeiro de Almeida C, Dhir S, Dhir A, Moghaddam A, Sattentau Q, Meinhart A, et al. RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination. Mol Cell. 2018;70:650-662.e8 pubmed 出版商

Garcia Martin E, Sánchez Gómez F, Amo G, García Menaya J, Cordobés C, Ayuso P, et al. Asthma and allergic rhinitis associate with the rs2229542 variant that induces a p.Lys90Glu mutation and compromises AKR1B1 protein levels. Hum Mutat. 2018;39:1081-1091 pubmed 出版商

Foidl B, Humpel C. Differential Hyperphosphorylation of Tau-S199, -T231 and -S396 in Organotypic Brain Slices of Alzheimer Mice. A Model to Study Early Tau Hyperphosphorylation Using Okadaic Acid. Front Aging Neurosci. 2018;10:113 pubmed 出版商

Wang F, Liu Z, Park S, Gwag T, Lu W, Ma M, et al. Myeloid ?-Catenin Deficiency Exacerbates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice. Arterioscler Thromb Vasc Biol. 2018;38:1468-1478 pubmed 出版商

Elaimy A, Guru S, Chang C, Ou J, Amante J, Zhu L, et al. VEGF-neuropilin-2 signaling promotes stem-like traits in breast cancer cells by TAZ-mediated repression of the Rac GAP β2-chimaerin. Sci Signal. 2018;11: pubmed 出版商

Hegge B, Sjøttem E, Mikkola I. Generation of a PAX6 knockout glioblastoma cell line with changes in cell cycle distribution and sensitivity to oxidative stress. BMC Cancer. 2018;18:496 pubmed 出版商

Nicole O, Bell D, Leste Lasserre T, Doat H, Guillemot F, Pacary E. A novel role for CAMKIIβ in the regulation of cortical neuron migration: implications for neurodevelopmental disorders. Mol Psychiatry. 2018;23:2209-2226 pubmed 出版商

Uprety B, Kaja A, Bhaumik S. TOR Facilitates the Targeting of the 19S Proteasome Subcomplex To Enhance Transcription Complex Assembly at the Promoters of the Ribosomal Protein Genes. Mol Cell Biol. 2018;38: pubmed 出版商

Campbell J, Heikkila J. Effect of hemin, baicalein and heme oxygenase-1 (HO-1) enzyme activity inhibitors on Cd-induced accumulation of HO-1, HSPs and aggresome-like structures in Xenopus kidney epithelial cells. Comp Biochem Physiol C Toxicol Pharmacol. 2018;210:1-17 pubmed 出版商

Middleton R, Rogers R, de Couto G, Tseliou E, Luther K, Holewinski R, et al. Newt cells secrete extracellular vesicles with therapeutic bioactivity in mammalian cardiomyocytes. J Extracell Vesicles. 2018;7:1456888 pubmed 出版商

O Neill S, Mathis M, Kovacic L, Zhang S, Reinhardt J, Scholz D, et al. Quantitative interaction analysis permits molecular insights into functional NOX4 NADPH oxidase heterodimer assembly. J Biol Chem. 2018;293:8750-8760 pubmed 出版商

Kim Y, Kwon M, Pak M, Park S, Baek J, Choi B. Beneficial Effects of Gagam-Palmultang on Scopolamine-Induced Memory Deficits in Mice. Evid Based Complement Alternat Med. 2018;2018:3479083 pubmed 出版商

Skowyra A, Allan L, Saurin A, Clarke P. USP9X Limits Mitotic Checkpoint Complex Turnover to Strengthen the Spindle Assembly Checkpoint and Guard against Chromosomal Instability. Cell Rep. 2018;23:852-865 pubmed 出版商

Tomoshige K, Guo M, Tsuchiya T, Fukazawa T, Fink Baldauf I, Stuart W, et al. An EGFR ligand promotes EGFR-mutant but not KRAS-mutant lung cancer in vivo. Oncogene. 2018;37:3894-3908 pubmed 出版商

Christensen K, Bahous R, Hou W, Deng L, Malysheva O, Arning E, et al. Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects. J Nutr. 2018;148:501-509 pubmed 出版商

Perrin L, Loizides Mangold U, Chanon S, Gobet C, Hulo N, Isenegger L, et al. Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle. elife. 2018;7: pubmed 出版商

Serwas N, Huemer J, Dieckmann R, Mejstrikova E, Garncarz W, Litzman J, et al. CEBPE-Mutant Specific Granule Deficiency Correlates With Aberrant Granule Organization and Substantial Proteome Alterations in Neutrophils. Front Immunol. 2018;9:588 pubmed 出版商

Wiegering A, Dildrop R, Kalfhues L, Spychala A, Kuschel S, Lier J, et al. Cell type-specific regulation of ciliary transition zone assembly in vertebrates. EMBO J. 2018;37: pubmed 出版商

Ledowski T, Nißler S, Wenk M, Pogatzki Zahn E, Segelcke D. Effects of muscle relaxants on ischaemia damage in skeletal muscle. Sci Rep. 2018;8:5794 pubmed 出版商

Parrilla Carrero J, Buchta W, Goswamee P, Culver O, McKendrick G, Harlan B, et al. Restoration of Kv7 Channel-Mediated Inhibition Reduces Cued-Reinstatement of Cocaine Seeking. J Neurosci. 2018;38:4212-4229 pubmed 出版商

Mendez Dorantes C, Bhargava R, Stark J. Repeat-mediated deletions can be induced by a chromosomal break far from a repeat, but multiple pathways suppress such rearrangements. Genes Dev. 2018;32:524-536 pubmed 出版商

Stern A, Ghura S, Gannon P, Akay Espinoza C, Phan J, Yee A, et al. BACE1 Mediates HIV-Associated and Excitotoxic Neuronal Damage Through an APP-Dependent Mechanism. J Neurosci. 2018;38:4288-4300 pubmed 出版商

Leirós L, Dáu J, Pinheiro D, Stumbo Machado A, Thole A, Cortez E, et al. Hematopoietic changes in the offspring induced by maternal overweight: Effect on placenta and fetal liver populations. Placenta. 2018;64:7-16 pubmed 出版商

Hickson S, Margineantu D, Hockenbery D, Simon J, Geballe A. Inhibition of vaccinia virus replication by nitazoxanide. Virology. 2018;518:398-405 pubmed 出版商

Malzer E, Dominicus C, Chambers J, Dickens J, Mookerjee S, Marciniak S. The integrated stress response regulates BMP signalling through effects on translation. BMC Biol. 2018;16:34 pubmed 出版商

Zhou S, Hong Q, Li Y, Li Q, Wang M. Autophagy contributes to regulate the ROS levels and PCD progress in TMV-infected tomatoes. Plant Sci. 2018;269:12-19 pubmed 出版商

Leiphrakpam P, Brattain M, Black J, Wang J. TGFβ and IGF1R signaling activates protein kinase A through differential regulation of ezrin phosphorylation in colon cancer cells. J Biol Chem. 2018;293:8242-8254 pubmed 出版商

Methot S, Litzler L, Subramani P, Eranki A, Fifield H, Patenaude A, et al. A licensing step links AID to transcription elongation for mutagenesis in B cells. Nat Commun. 2018;9:1248 pubmed 出版商

de Toeuf B, Soin R, Nazih A, Dragojevic M, Jurenas D, Delacourt N, et al. ARE-mediated decay controls gene expression and cellular metabolism upon oxygen variations. Sci Rep. 2018;8:5211 pubmed 出版商

Gotru S, Gil Pulido J, Beyersdorf N, Diefenbach A, Becker I, Vögtle T, et al. Cutting Edge: Imbalanced Cation Homeostasis in MAGT1-Deficient B Cells Dysregulates B Cell Development and Signaling in Mice. J Immunol. 2018;200:2529-2534 pubmed 出版商

Ozhathil L, Delalande C, Bianchi B, Nemeth G, Kappel S, Thomet U, et al. Identification of potent and selective small molecule inhibitors of the cation channel TRPM4. Br J Pharmacol. 2018;175:2504-2519 pubmed 出版商

Fan R, Schrott L, Arnold T, Snelling S, Rao M, Graham D, et al. Chronic oxycodone induces axonal degeneration in rat brain. BMC Neurosci. 2018;19:15 pubmed 出版商

Bianchi B, Ozhathil L, Medeiros Domingo A, Gollob M, Abriel H. Four TRPM4 Cation Channel Mutations Found in Cardiac Conduction Diseases Lead to Altered Protein Stability. Front Physiol. 2018;9:177 pubmed 出版商

Kiselev Y, Andersen S, Johannessen C, Fjukstad B, Standahl Olsen K, Stenvold H, et al. Transcription factor PAX6 as a novel prognostic factor and putative tumour suppressor in non-small cell lung cancer. Sci Rep. 2018;8:5059 pubmed 出版商

Shilnikova K, Piao M, Kang K, Ryu Y, Park J, Hyun Y, et al. Shikonin induces mitochondria-mediated apoptosis and attenuates epithelial-mesenchymal transition in cisplatin-resistant human ovarian cancer cells. Oncol Lett. 2018;15:5417-5424 pubmed 出版商

Dyck S, Kataria H, Alizadeh A, Santhosh K, Lang B, Silver J, et al. Perturbing chondroitin sulfate proteoglycan signaling through LAR and PTPσ receptors promotes a beneficial inflammatory response following spinal cord injury. J Neuroinflammation. 2018;15:90 pubmed 出版商

Hamilton M, Bols N, Duncker B. The characterization of ?H2AX and p53 as biomarkers of genotoxic stress in a rainbow trout (Oncorhynchus mykiss) brain cell line. Chemosphere. 2018;201:850-858 pubmed 出版商

Sertic S, Mollica A, Campus I, Roma S, Tumini E, Aguilera A, et al. Coordinated Activity of Y Family TLS Polymerases and EXO1 Protects Non-S Phase Cells from UV-Induced Cytotoxic Lesions. Mol Cell. 2018;70:34-47.e4 pubmed 出版商

Shavva V, Bogomolova A, Efremov A, Trofimov A, Nikitin A, Babina A, et al. Insulin downregulates C3 gene expression in human HepG2 cells through activation of PPAR?. Eur J Cell Biol. 2018;97:204-215 pubmed 出版商

Ranieri C, Di Tommaso S, Loconte D, Grossi V, Sanese P, Bagnulo R, et al. In vitro efficacy of ARQ 092, an allosteric AKT inhibitor, on primary fibroblast cells derived from patients with PIK3CA-related overgrowth spectrum (PROS). Neurogenetics. 2018;19:77-91 pubmed 出版商

Katz C, Low Calle A, Choe J, Laptenko O, Tong D, Joseph Chowdhury J, et al. Wild-type and cancer-related p53 proteins are preferentially degraded by MDM2 as dimers rather than tetramers. Genes Dev. 2018;32:430-447 pubmed 出版商

Meier S, Gilad A, Brandon J, Qian C, Gao E, Abisambra J, et al. Non-invasive detection of adeno-associated viral gene transfer using a genetically encoded CEST-MRI reporter gene in the murine heart. Sci Rep. 2018;8:4638 pubmed 出版商

Baktash Y, Madhav A, Coller K, Randall G. Single Particle Imaging of Polarized Hepatoma Organoids upon Hepatitis C Virus Infection Reveals an Ordered and Sequential Entry Process. Cell Host Microbe. 2018;23:382-394.e5 pubmed 出版商

Giralt A, Denechaud P, Lopez Mejia I, Delacuisine B, Blanchet E, Bonner C, et al. E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes. Mol Metab. 2018;11:104-112 pubmed 出版商

Li C, Irrazabal T, So C, Berru M, Du L, Lam E, et al. The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining. Nat Commun. 2018;9:1006 pubmed 出版商

Lacal P, Atzori M, Ruffini F, Tentori L, Graziani G. Poly(ADP-ribose) polymerase inhibitor olaparib hampers placental growth factor-driven activation of myelomonocytic cells. Oncol Rep. 2018;39:2261-2269 pubmed 出版商

Goto H, Nishio M, To Y, Oishi T, Miyachi Y, Maehama T, et al. Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEAD-dependent repression of SOX9. Development. 2018;145: pubmed 出版商

Corrochano S, Blanco G, Williams D, Wettstein J, Simon M, Kumar S, et al. A genetic modifier suggests that endurance exercise exacerbates Huntington's disease. Hum Mol Genet. 2018;27:1723-1731 pubmed 出版商

Kim S, Matsumoto T, Kagawa H, Nakamura M, Hirohata R, Ueno A, et al. Microhomology-assisted scarless genome editing in human iPSCs. Nat Commun. 2018;9:939 pubmed 出版商

Chen Roetling J, Ma S, Cao Y, Shah A, Regan R. Hemopexin increases the neurotoxicity of hemoglobin when haptoglobin is absent. J Neurochem. 2018;145:464-473 pubmed 出版商

Qi C, Wang X, Shen Z, Chen S, Yu H, Williams N, et al. Anti-mitotic chemotherapeutics promote apoptosis through TL1A-activated death receptor 3 in cancer cells. Cell Res. 2018;28:544-555 pubmed 出版商

Teh J, Cheng P, Purwin T, Nikbakht N, Patel P, Chervoneva I, et al. In Vivo E2F Reporting Reveals Efficacious Schedules of MEK1/2-CDK4/6 Targeting and mTOR-S6 Resistance Mechanisms. Cancer Discov. 2018;8:568-581 pubmed 出版商

Cassinotti L, Guil M, Schöller M, Navarro M, Bianciotti L, Vatta M. Chronic Blockade of Brain Endothelin Receptor Type-A (ETA) Reduces Blood Pressure and Prevents Catecholaminergic Overactivity in the Right Olfactory Bulb of DOCA-Salt Hypertensive Rats. Int J Mol Sci. 2018;19: pubmed 出版商

Blank V, Bellizzi Y, Zotta E, Cornier P, Delpiccolo C, Boggián D, et al. A novel penicillin derivative induces antitumor effect in melanoma cells. Anticancer Drugs. 2018;29:416-428 pubmed 出版商

Lesuis S, Weggen S, Baches S, Lucassen P, Krugers H. Targeting glucocorticoid receptors prevents the effects of early life stress on amyloid pathology and cognitive performance in APP/PS1 mice. Transl Psychiatry. 2018;8:53 pubmed 出版商

Singh A, Sharma S, Pagarware K, Siraji R, Ansari I, Mandal A, et al. Enteropathogenic E. coli effectors EspF and Map independently disrupt tight junctions through distinct mechanisms involving transcriptional and post-transcriptional regulation. Sci Rep. 2018;8:3719 pubmed 出版商

Ma Z. Downregulation of SETD8 by miR-382 is involved in glioma progression. Pathol Res Pract. 2018;214:356-360 pubmed 出版商

Nishizawa Y, Konno M, Asai A, Koseki J, Kawamoto K, Miyoshi N, et al. Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer. Oncotarget. 2018;9:7476-7486 pubmed 出版商

Kang X, Cui C, Wang C, Wu G, Chen H, Lu Z, et al. CAMKs support development of acute myeloid leukemia. J Hematol Oncol. 2018;11:30 pubmed 出版商

Alberti C, Manzenreither R, Sowemimo I, Burkard T, Wang J, Mahofsky K, et al. Cell-type specific sequencing of microRNAs from complex animal tissues. Nat Methods. 2018;15:283-289 pubmed 出版商

Emperador S, Vidal M, Hernandez Ainsa C, Ruiz Ruiz C, Woods D, Morales Becerra A, et al. The Decrease in Mitochondrial DNA Mutation Load Parallels Visual Recovery in a Leber Hereditary Optic Neuropathy Patient. Front Neurosci. 2018;12:61 pubmed 出版商

Nguyen L, Anderson A. mTOR-dependent alterations of Kv1.1 subunit expression in the neuronal subset-specific Pten knockout mouse model of cortical dysplasia with epilepsy. Sci Rep. 2018;8:3568 pubmed 出版商

Göder A, Emmerich C, Nikolova T, Kiweler N, Schreiber M, Kühl T, et al. HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130. Nat Commun. 2018;9:764 pubmed 出版商

Thiyagarajan D, Pedersen H, Seredkina N, Horvei K, Arranz L, Sonneveld R, et al. IL-1β Promotes a New Function of DNase I as a Transcription Factor for the Fas Receptor Gene. Front Cell Dev Biol. 2018;6:7 pubmed 出版商

Smestad J, Hamidi O, Wang L, Holte M, Khazal F, Erber L, et al. Characterization and metabolic synthetic lethal testing in a new model of SDH-loss familial pheochromocytoma and paraganglioma. Oncotarget. 2018;9:6109-6127 pubmed 出版商

Müller C, Charniga C, Temple S, Finnemann S. Quantified F-Actin Morphology Is Predictive of Phagocytic Capacity of Stem Cell-Derived Retinal Pigment Epithelium. Stem Cell Reports. 2018;10:1075-1087 pubmed 出版商

Noguchi A, Adachi S, Yokota N, Hatta T, Natsume T, Kawahara H. ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest. Biol Open. 2018;7: pubmed 出版商

Masuike Y, Tanaka K, Makino T, Yamasaki M, Miyazaki Y, Takahashi T, et al. Esophageal squamous cell carcinoma with low mitochondrial copy number has mesenchymal and stem-like characteristics, and contributes to poor prognosis. PLoS ONE. 2018;13:e0193159 pubmed 出版商

Qu S, Xue H, Dong X, Lin D, Wu R, Nabavi N, et al. Aneustat (OMN54) has aerobic glycolysis-inhibitory activity and also immunomodulatory activity as indicated by a first-generation PDX prostate cancer model. Int J Cancer. 2018;143:419-429 pubmed 出版商

Scharf I, Bierbaumer L, Huber H, Wittmann P, Haider C, Pirker C, et al. Dynamics of CRISPR/Cas9-mediated genomic editing of the AXL locus in hepatocellular carcinoma cells. Oncol Lett. 2018;15:2441-2450 pubmed 出版商

Marshall M, Issa Y, Jakubauskas B, Stoskute M, Elackattu V, Marshall J, et al. Long-Term Improvement of Neurological Signs and Metabolic Dysfunction in a Mouse Model of Krabbe's Disease after Global Gene Therapy. Mol Ther. 2018;26:874-889 pubmed 出版商

Moyano A, Steplowski J, Wang H, Son K, Rapolti D, Marshall J, et al. microRNA-219 Reduces Viral Load and Pathologic Changes in Theiler's Virus-Induced Demyelinating Disease. Mol Ther. 2018;26:730-743 pubmed 出版商

Wilson R, Drake J, Cui D, Lewellen B, Fisher C, Zhang M, et al. Mitochondrial protein S-nitrosation protects against ischemia reperfusion-induced denervation at neuromuscular junction in skeletal muscle. Free Radic Biol Med. 2018;117:180-190 pubmed 出版商

Fielding A, Concannon M, Darling S, Rusilowicz Jones E, Sacco J, Prior I, et al. The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity. Oncogene. 2018;37:2326-2342 pubmed 出版商

Nishida K, Tamura A, Yui N. ER stress-mediated autophagic cell death induction through methylated β-cyclodextrins-threaded acid-labile polyrotaxanes. J Control Release. 2018;275:20-31 pubmed 出版商

Sztal T, McKaige E, Williams C, Ruparelia A, Bryson Richardson R. Genetic compensation triggered by actin mutation prevents the muscle damage caused by loss of actin protein. PLoS Genet. 2018;14:e1007212 pubmed 出版商

Skovgaard C, Christiansen D, Christensen P, Almquist N, Thomassen M, Bangsbo J. Effect of speed endurance training and reduced training volume on running economy and single muscle fiber adaptations in trained runners. Physiol Rep. 2018;6: pubmed 出版商

Lee J, Yang D, Park S, Han H, Park J, Kim B, et al. Trichostatin A resistance is facilitated by HIF-1α acetylation in HeLa human cervical cancer cells under normoxic conditions. Oncotarget. 2018;9:2035-2049 pubmed 出版商

Ferrucci F, Ciaccio R, Monticelli S, Pigini P, Di Giacomo S, Purgato S, et al. MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma. Biochim Biophys Acta Gene Regul Mech. 2018;1861:235-245 pubmed 出版商

Manzanares M, Campbell D, Maldonado G, Sirica A. Overexpression of periostin and distinct mesothelin forms predict malignant progression in a rat cholangiocarcinoma model. Hepatol Commun. 2018;2:155-172 pubmed 出版商

Liu J, Mustafa S, Barratt D, Hutchinson M. Corticosterone Preexposure Increases NF-κB Translocation and Sensitizes IL-1β Responses in BV2 Microglia-Like Cells. Front Immunol. 2018;9:3 pubmed 出版商

Yan X, Liu J, Wang X, Li W, Chen J, Sun H. Pretreatment with AQP4 and NKCC1 Inhibitors Concurrently Attenuated Spinal Cord Edema and Tissue Damage after Spinal Cord Injury in Rats. Front Physiol. 2018;9:6 pubmed 出版商

Kruppa A, Kishi Itakura C, Masters T, Rorbach J, Grice G, Kendrick Jones J, et al. Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria. Dev Cell. 2018;44:484-499.e6 pubmed 出版商

Liuzzi J, Narayanan V, Doan H, Yoo C. Effect of zinc intake on hepatic autophagy during acute alcohol intoxication. Biometals. 2018;31:217-232 pubmed 出版商

Kim Y, Ahn S, Pak M, Lee H, Jung D, Shin Y, et al. Potential benefits of mesenchymal stem cells and electroacupuncture on the trophic factors associated with neurogenesis in mice with ischemic stroke. Sci Rep. 2018;8:2044 pubmed 出版商

Elbitar S, Susan Resiga D, Ghaleb Y, El Khoury P, Peloso G, Stitziel N, et al. New Sequencing technologies help revealing unexpected mutations in Autosomal Dominant Hypercholesterolemia. Sci Rep. 2018;8:1943 pubmed 出版商

Brocard M, Khasnis S, Wood C, Shannon Lowe C, West M. Pumilio directs deadenylation-associated translational repression of the cyclin-dependent kinase 1 activator RGC-32. Nucleic Acids Res. 2018;46:3707-3725 pubmed 出版商

Qu S, Ci X, Xue H, Dong X, Hao J, Lin D, et al. Treatment with docetaxel in combination with Aneustat leads to potent inhibition of metastasis in a patient-derived xenograft model of advanced prostate cancer. Br J Cancer. 2018;118:802-812 pubmed 出版商

Struchtrup A, Wiegering A, Stork B, Ruther U, Gerhardt C. The ciliary protein RPGRIP1L governs autophagy independently of its proteasome-regulating function at the ciliary base in mouse embryonic fibroblasts. Autophagy. 2018;14:567-583 pubmed 出版商

Oh J, Perry J, Pua H, Irgens Möller N, Ishido S, Hsieh C, et al. MARCH1 protects the lipid raft and tetraspanin web from MHCII proteotoxicity in dendritic cells. J Cell Biol. 2018;217:1395-1410 pubmed 出版商

Munakata Y, Yamada T, Imai J, Takahashi K, Tsukita S, Shirai Y, et al. Olfactory receptors are expressed in pancreatic β-cells and promote glucose-stimulated insulin secretion. Sci Rep. 2018;8:1499 pubmed 出版商

Sui Y, Liu Z, Park S, Thatcher S, Zhu B, Fernandez J, et al. IKKβ is a β-catenin kinase that regulates mesenchymal stem cell differentiation. JCI Insight. 2018;3: pubmed 出版商

Hříbková H, Grabiec M, Klemová D, Slaninova I, Sun Y. Calcium signaling mediates five types of cell morphological changes to form neural rosettes. J Cell Sci. 2018;131: pubmed 出版商

Zezina E, Snodgrass R, Schreiber Y, Zukunft S, Schürmann C, Heringdorf D, et al. Mitochondrial fragmentation in human macrophages attenuates palmitate-induced inflammatory responses. Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863:433-446 pubmed 出版商

Farnoodian M, Sorenson C, Sheibani N. PEDF expression affects the oxidative and inflammatory state of choroidal endothelial cells. Am J Physiol Cell Physiol. 2018;314:C456-C472 pubmed 出版商

Patel P, Tsiperson V, Gottesman S, Somma J, Blain S. Dual Inhibition of CDK4 and CDK2 via Targeting p27 Tyrosine Phosphorylation Induces a Potent and Durable Response in Breast Cancer Cells. Mol Cancer Res. 2018;16:361-377 pubmed 出版商

Bekkering S, Arts R, Novakovic B, Kourtzelis I, van der Heijden C, Li Y, et al. Metabolic Induction of Trained Immunity through the Mevalonate Pathway. Cell. 2018;172:135-146.e9 pubmed 出版商

Li H, Zou T, Meng S, Peng Y, Yang J. p21 protects cardiomyocytes against ischemia-reperfusion injury by inhibiting oxidative stress. Mol Med Rep. 2018;17:4665-4671 pubmed 出版商

Rajagopal R, Zhang S, Wei X, Doggett T, Adak S, Enright J, et al. Retinal de novo lipogenesis coordinates neurotrophic signaling to maintain vision. JCI Insight. 2018;3: pubmed 出版商

Jonckheere V, Fijałkowska D, Van Damme P. Omics Assisted N-terminal Proteoform and Protein Expression Profiling On Methionine Aminopeptidase 1 (MetAP1) Deletion. Mol Cell Proteomics. 2018;17:694-708 pubmed 出版商

Yang A, Herter Sprie G, Zhang H, Lin E, Biancur D, Wang X, et al. Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms. Cancer Discov. 2018;8:276-287 pubmed 出版商

Pini A, Grange C, Veglia E, Argenziano M, Cavalli R, Guasti D, et al. Histamine H4 receptor antagonism prevents the progression of diabetic nephropathy in male DBA2/J mice. Pharmacol Res. 2018;128:18-28 pubmed 出版商

Han S, Ren Y, He W, Liu H, Zhi Z, Zhu X, et al. ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma. Nat Commun. 2018;9:28 pubmed 出版商

Ohashi T, Eguchi H, Kawamoto K, Konno M, Asai A, Colvin H, et al. Mitochondrial pyruvate carrier modulates the epithelial-mesenchymal transition in cholangiocarcinoma. Oncol Rep. 2018;39:1276-1282 pubmed 出版商

Cui J, Yu S, Li Y, Li P, Liu F. Direct binding of Toll-like receptor 4 to ionotropic glutamate receptor N-methyl-D-aspartate subunit 1 induced by lipopolysaccharide in microglial cells N9 and EOC 20. Int J Mol Med. 2018;41:1323-1330 pubmed 出版商

Winter S, Martin E, Boutboul D, Lenoir C, Boudjemaa S, Petit A, et al. Loss of RASGRP1 in humans impairs T-cell expansion leading to Epstein-Barr virus susceptibility. EMBO Mol Med. 2018;10:188-199 pubmed 出版商

Child S, Hickson S, Bayer A, Malouli D, Fruh K, Geballe A. Antagonism of the Protein Kinase R Pathway in Human Cells by Rhesus Cytomegalovirus. J Virol. 2018;92: pubmed 出版商

Prattichizzo F, De Nigris V, Mancuso E, Spiga R, Giuliani A, Matacchione G, et al. Short-term sustained hyperglycaemia fosters an archetypal senescence-associated secretory phenotype in endothelial cells and macrophages. Redox Biol. 2018;15:170-181 pubmed 出版商

Garza Morales R, Yaddanapudi K, Perez Hernandez R, Riedinger E, McMasters K, Shirwan H, et al. Temozolomide renders murine cancer cells susceptible to oncolytic adenovirus replication and oncolysis. Cancer Biol Ther. 2018;19:188-197 pubmed 出版商

Rajbhandari P, Thomas B, Feng A, Hong C, Wang J, Vergnes L, et al. IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure. Cell. 2018;172:218-233.e17 pubmed 出版商

DeGregorio Rocasolano N, Martí Sistac O, Ponce J, Castelló Ruiz M, Millan M, Guirao V, et al. Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent neuronal damage. Redox Biol. 2018;15:143-158 pubmed 出版商

Pinto M, Nissanka N, Moraes C. Lack of Parkin Anticipates the Phenotype and Affects Mitochondrial Morphology and mtDNA Levels in a Mouse Model of Parkinson's Disease. J Neurosci. 2018;38:1042-1053 pubmed 出版商

Mnasri N, Mamarbachi M, Allen B, Mayer G. 5-Azacytidine engages an IRE1?-EGFR-ERK1/2 signaling pathway that stabilizes the LDL receptor mRNA. Biochim Biophys Acta Gene Regul Mech. 2018;1861:29-40 pubmed 出版商

Ziegler C, Eisenhauer P, Kelly J, Dang L, Beganovic V, Bruce E, et al. A Proteomics Survey of Junín Virus Interactions with Human Proteins Reveals Host Factors Required for Arenavirus Replication. J Virol. 2018;92: pubmed 出版商

Jean Louis T, Rockwell P, Figueiredo Pereira M. Prostaglandin J2 promotes O-GlcNAcylation raising APP processing by α- and β-secretases: relevance to Alzheimer's disease. Neurobiol Aging. 2018;62:130-145 pubmed 出版商

Wang S, Brunne B, Zhao S, Chai X, Li J, Lau J, et al. Trajectory Analysis Unveils Reelin's Role in the Directed Migration of Granule Cells in the Dentate Gyrus. J Neurosci. 2018;38:137-148 pubmed 出版商

Petrus P, Bialešová L, Checa A, Kerr A, Naz S, Backdahl J, et al. Adipocyte Expression of SLC19A1 Links DNA Hypermethylation to Adipose Tissue Inflammation and Insulin Resistance. J Clin Endocrinol Metab. 2018;103:710-721 pubmed 出版商

Ameen G, Mora S. Cbl downregulation increases RBP4 expression in adipocytes of female mice. J Endocrinol. 2018;236:29-41 pubmed 出版商

Liu C, Sun X, Wang Z, Le Q, Liu P, Jiang C, et al. Retrieval-Induced Upregulation of Tet3 in Pyramidal Neurons of the Dorsal Hippocampus Mediates Cocaine-Associated Memory Reconsolidation. Int J Neuropsychopharmacol. 2018;21:255-266 pubmed 出版商

Masso A, Sanchez A, Bosch A, Gimenez Llort L, Chillon M. Secreted αKlotho isoform protects against age-dependent memory deficits. Mol Psychiatry. 2018;23:1937-1947 pubmed 出版商

Fujita S, Mukai T, Mito T, Kodama S, Nagasu A, Kittaka M, et al. Pharmacological inhibition of tankyrase induces bone loss in mice by increasing osteoclastogenesis. Bone. 2018;106:156-166 pubmed 出版商

Marturano Kruik A, Villasante A, Yaeger K, Ambati S, Chramiec A, Raimondi M, et al. Biomechanical regulation of drug sensitivity in an engineered model of human tumor. Biomaterials. 2018;150:150-161 pubmed 出版商

Faulkner S, Jobling P, Rowe C, Rodrigues Oliveira S, Roselli S, Thorne R, et al. Neurotrophin Receptors TrkA, p75NTR, and Sortilin Are Increased and Targetable in Thyroid Cancer. Am J Pathol. 2018;188:229-241 pubmed 出版商

Zhang S, Eitan E, Wu T, Mattson M. Intercellular transfer of pathogenic α-synuclein by extracellular vesicles is induced by the lipid peroxidation product 4-hydroxynonenal. Neurobiol Aging. 2018;61:52-65 pubmed 出版商

Young C, Chira N, Róg J, Al Khalidi R, Benard M, Galas L, et al. Sustained activation of P2X7 induces MMP-2-evoked cleavage and functional purinoceptor inhibition. J Mol Cell Biol. 2018;10:229-242 pubmed 出版商

Youn H, Lee H, Sohn H, Park U, Kim E, Youn B, et al. RaRF confers RA resistance by sequestering RAR to the nucleolus and regulating MCL1 in leukemia cells. Oncogene. 2018;37:352-362 pubmed 出版商

Skovgaard C, Almquist N, Kvorning T, Christensen P, Bangsbo J. Effect of tapering after a period of high-volume sprint interval training on running performance and muscular adaptations in moderately trained runners. J Appl Physiol (1985). 2018;124:259-267 pubmed 出版商

Sanz Blasco S, Bordone M, Damianich A, Gomez G, Bernardi M, Isaja L, et al. The Kinase Fyn As a Novel Intermediate in L-DOPA-Induced Dyskinesia in Parkinson's Disease. Mol Neurobiol. 2018;55:5125-5136 pubmed 出版商

Boonstra K, Bloemberg D, Quadrilatero J. Caspase-2 is required for skeletal muscle differentiation and myogenesis. Biochim Biophys Acta Mol Cell Res. 2018;1865:95-104 pubmed 出版商

Lee S, Kim J, Lee J, Lee J, Han J. Non-invasive monitoring of the therapeutic response in sorafenib-treated hepatocellular carcinoma based on photoacoustic imaging. Eur Radiol. 2018;28:372-381 pubmed 出版商

Moutal A, Villa L, Yeon S, Householder K, Park K, Sirianni R, et al. CRMP2 Phosphorylation Drives Glioblastoma Cell Proliferation. Mol Neurobiol. 2018;55:4403-4416 pubmed 出版商

Skovgaard C, Almquist N, Bangsbo J. The effect of repeated periods of speed endurance training on performance, running economy, and muscle adaptations. Scand J Med Sci Sports. 2018;28:381-390 pubmed 出版商

Bussières Marmen S, Vinette V, Gungabeesoon J, Aubry I, Pérez Quintero L, Tremblay M. Loss of T-cell protein tyrosine phosphatase in the intestinal epithelium promotes local inflammation by increasing colonic stem cell proliferation. Cell Mol Immunol. 2018;15:367-376 pubmed 出版商

Jun Y, Lee Y, Lee J, Kaang B, Jang D. Distinct regulations of ARF1 by two Aplysia Sec7 isoforms. Anim Cells Syst (Seoul). 2017;21:10-16 pubmed 出版商

Horie N, Hikita A, Nishizawa S, Uto S, Takato T, Hoshi K. Impairment of the transition from proliferative stage to prehypertrophic stage in chondrogenic differentiation of human induced pluripotent stem cells harboring the causative mutation of achondroplasia in fibroblast growth factor receptor 3. Regen Ther. 2017;6:15-20 pubmed 出版商

von Manstein V, Groner B. Tumor cell resistance against targeted therapeutics: the density of cultured glioma tumor cells enhances Stat3 activity and offers protection against the tyrosine kinase inhibitor canertinib. Medchemcomm. 2017;8:96-102 pubmed 出版商

Ghosh A, Desai A, Ravi V, Narayanappa G, Tyagi B. Chikungunya Virus Interacts with Heat Shock Cognate 70 Protein to Facilitate Its Entry into Mosquito Cell Line. Intervirology. 2017;60:247-262 pubmed 出版商

Colin D, Inkster J, Germain S, Seimbille Y. Preclinical validations of [18F]FPyPEGCBT-c(RGDfK): a 18F-labelled RGD peptide prepared by ligation of 2-cyanobenzothiazole and 1,2-aminothiol to image angiogenesis. EJNMMI Radiopharm Chem. 2017;1:16 pubmed 出版商

Schulze R, Rasineni K, Weller S, Schott M, Schroeder B, Casey C, et al. Ethanol exposure inhibits hepatocyte lipophagy by inactivating the small guanosine triphosphatase Rab7. Hepatol Commun. 2017;1:140-152 pubmed 出版商

Veistinen L, Mustonen T, Hasan M, Takatalo M, Kobayashi Y, Kesper D, et al. Regulation of Calvarial Osteogenesis by Concomitant De-repression of GLI3 and Activation of IHH Targets. Front Physiol. 2017;8:1036 pubmed 出版商

Heinz L, Muhs S, Schiewek J, Grüb S, Nalaskowski M, Lin Y, et al. Strong fascin expression promotes metastasis independent of its F-actin bundling activity. Oncotarget. 2017;8:110077-110091 pubmed 出版商

Zahoor M, Westhrin M, Aass K, Moen S, Misund K, Psonka Antonczyk K, et al. Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss. Blood Adv. 2017;1:2656-2666 pubmed 出版商

Kaller M, Götz U, Hermeking H. Loss of p53-inducible long non-coding RNA LINC01021 increases chemosensitivity. Oncotarget. 2017;8:102783-102800 pubmed 出版商

Dittmann K, Mayer C, Czemmel S, Huber S, Rodemann H. New roles for nuclear EGFR in regulating the stability and translation of mRNAs associated with VEGF signaling. PLoS ONE. 2017;12:e0189087 pubmed 出版商

Nishi K, Iwaihara Y, Tsunoda T, Doi K, Sakata T, Shirasawa S, et al. ROS-induced cleavage of NHLRC2 by caspase-8 leads to apoptotic cell death in the HCT116 human colon cancer cell line. Cell Death Dis. 2017;8:3218 pubmed 出版商

Zhang L, JABLONSKI A, Mojsilovic Petrovic J, Ding H, Seeholzer S, Newton I, et al. SAP97 Binding Partner CRIPT Promotes Dendrite Growth In Vitro and In Vivo. Eneuro. 2017;4: pubmed 出版商

Onyango D, Lee G, Stark J. PRPF8 is important for BRCA1-mediated homologous recombination. Oncotarget. 2017;8:93319-93337 pubmed 出版商

Saison Ridinger M, DelGiorno K, Zhang T, Kraus A, French R, Jaquish D, et al. Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy. PLoS ONE. 2017;12:e0189051 pubmed 出版商

Yamamoto J, Imai J, Izumi T, Takahashi H, Kawana Y, Takahashi K, et al. Neuronal signals regulate obesity induced β-cell proliferation by FoxM1 dependent mechanism. Nat Commun. 2017;8:1930 pubmed 出版商

Park S, Yoon S, Sun E, Zhou R, Bae J, Seo Y, et al. Glycoprotein 90K Promotes E-Cadherin Degradation in a Cell Density-Dependent Manner via Dissociation of E-Cadherin-p120-Catenin Complex. Int J Mol Sci. 2017;18: pubmed 出版商

Parrini M, Ghezzi D, Deidda G, Medrihan L, Castroflorio E, Alberti M, et al. Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome. Sci Rep. 2017;7:16825 pubmed 出版商

Hartupee J, Szalai G, Wang W, Ma X, Diwan A, Mann D. Impaired Protein Quality Control During Left Ventricular Remodeling in Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor. Circ Heart Fail. 2017;10: pubmed 出版商

Sidoryk Wegrzynowicz M, Gerber Y, Ries M, Sastre M, Tolkovsky A, Spillantini M. Astrocytes in mouse models of tauopathies acquire early deficits and lose neurosupportive functions. Acta Neuropathol Commun. 2017;5:89 pubmed 出版商

Aldaba Muruato L, Muñoz Ortega M, Macías Pérez J, Pulido Ortega J, Martínez Hernández S, Ventura Juárez J. Adrenergic regulation during acute hepatic infection with Entamoeba histolytica in the hamster: involvement of oxidative stress, Nrf2 and NF-KappaB. Parasite. 2017;24:46 pubmed 出版商

Smith L, Farzan R, Ali S, Buluwela L, Saurin A, Meek D. The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation. Sci Rep. 2017;7:16115 pubmed 出版商

Furukawa H, Makino T, Yamasaki M, Tanaka K, Miyazaki Y, Takahashi T, et al. PRIMA-1 induces p53-madiated apoptosis by upregulating Noxa in esophageal squamous cell carcinoma with TP53 missense mutation. Cancer Sci. 2017;: pubmed 出版商

Allavena G, Cuomo F, Baumgartner G, Bele T, Sellgren A, Oo K, et al. Suppressed translation as a mechanism of initiation of CASP8 (caspase 8)-dependent apoptosis in autophagy-deficient NSCLC cells under nutrient limitation. Autophagy. 2017;:1-35 pubmed 出版商

Mueck K, Rebholz S, Harati M, Rodemann H, Toulany M. Akt1 Stimulates Homologous Recombination Repair of DNA Double-Strand Breaks in a Rad51-Dependent Manner. Int J Mol Sci. 2017;18: pubmed 出版商

Shimada H, Satohisa S, Kohno T, Konno T, Takano K, Takahashi S, et al. Downregulation of lipolysis-stimulated lipoprotein receptor promotes cell invasion via claudin-1-mediated matrix metalloproteinases in human endometrial cancer. Oncol Lett. 2017;14:6776-6782 pubmed 出版商

Boix J, Bigas J, Sevilla L, Iacobone M, Citton M, Torresan F, et al. Primary aldosteronism patients show skin alterations and abnormal activation of glucocorticoid receptor in keratinocytes. Sci Rep. 2017;7:15806 pubmed 出版商

Bradshaw N, Ukkola Vuoti L, Pankakoski M, Zheutlin A, Ortega Alonso A, Torniainen Holm M, et al. The NDE1 genomic locus can affect treatment of psychiatric illness through gene expression changes related to microRNA-484. Open Biol. 2017;7: pubmed 出版商

Blixt M, Konjusha D, Ring H, Hallböök F. The zinc finger gene Nolz1 regulates the formation of retinal progenitor cells and suppresses the Lim3/Lhx3 phenotype of retinal bipolar cells in chicken retina. Dev Dyn. 2017;: pubmed 出版商

Ju Lee H, Bartsch D, Xiao C, Guerrero S, Ahuja G, Schindler C, et al. A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells. Nat Commun. 2017;8:1456 pubmed 出版商

Olivera Santa Catalina M, Caballero Bermejo M, Argent R, Alonso J, Centeno F, Lorenzo M. JNK signaling pathway regulates sorbitol-induced Tau proteolysis and apoptosis in SH-SY5Y cells by targeting caspase-3. Arch Biochem Biophys. 2017;636:42-49 pubmed 出版商

Espadinha A, Prouzet Mauleon V, Claverol S, Lagarde V, Bonneu M, Mahon F, et al. A tyrosine kinase-STAT5-miR21-PDCD4 regulatory axis in chronic and acute myeloid leukemia cells. Oncotarget. 2017;8:76174-76188 pubmed 出版商

Massip Copiz M, Clauzure M, Valdivieso A, Santa Coloma T. Epiregulin (EREG) is upregulated through an IL-1? autocrine loop in Caco-2 epithelial cells with reduced CFTR function. J Cell Biochem. 2017;: pubmed 出版商

Al Akhrass H, Naves T, Vincent F, Magnaudeix A, Durand K, Bertin F, et al. Sortilin limits EGFR signaling by promoting its internalization in lung cancer. Nat Commun. 2017;8:1182 pubmed 出版商

Lee S, Kim J, Lee J, Zen Y, Han J. Imaging Monitoring of Kupffer Cell Function and Hepatic Oxygen Saturation in Preneoplastic Changes During Cholangiocarcinogenesis. Sci Rep. 2017;7:14203 pubmed 出版商

Arts F, Keogh L, Smyth P, O Toole S, Ta R, Gleeson N, et al. miR-223 potentially targets SWI/SNF complex protein SMARCD1 in atypical proliferative serous tumor and high-grade ovarian serous carcinoma. Hum Pathol. 2017;70:98-104 pubmed 出版商

Ghasemi F, Black M, Vizeacoumar F, Pinto N, Ruicci K, Le C, et al. Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer. Oncotarget. 2017;8:71512-71519 pubmed 出版商

Zhang L, Rajbhandari P, Priest C, Sandhu J, Wu X, TEMEL R, et al. Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP. elife. 2017;6: pubmed 出版商

Bian Q, Lu J, Zhang L, Chi Y, Li Y, Guo H. Highly pathogenic avian influenza A virus H5N1 non-structural protein 1 is associated with apoptotic activation of the intrinsic mitochondrial pathway. Exp Ther Med. 2017;14:4041-4046 pubmed 出版商

Rodriguez Rodriguez P, Sandebring Matton A, Merino Serrais P, Parrado Fernandez C, Rabano A, Winblad B, et al. Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons. Brain. 2017;: pubmed 出版商

KENNEDY D, Mnich K, Oommen D, Chakravarthy R, Almeida Souza L, Krols M, et al. HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis. Cell Death Dis. 2017;8:e3026 pubmed 出版商

Pirou C, Montazer Torbati F, Jah N, Delmas E, Lasbleiz C, Mignotte B, et al. FGF1 protects neuroblastoma SH-SY5Y cells from p53-dependent apoptosis through an intracrine pathway regulated by FGF1 phosphorylation. Cell Death Dis. 2017;8:e3023 pubmed 出版商

Kim H, Lee W. Low-intensity aerobic exercise training: inhibition of skeletal muscle atrophy in high-fat-diet-induced ovariectomized rats. J Exerc Nutrition Biochem. 2017;21:19-25 pubmed 出版商

Chen G, Zhou G, Aras S, He Z, Lucas S, Podgorski I, et al. Loss of ABHD5 promotes the aggressiveness of prostate cancer cells. Sci Rep. 2017;7:13021 pubmed 出版商

Yamashita K, Miyata H, Makino T, Masuike Y, Furukawa H, Tanaka K, et al. High Expression of the Mitophagy-Related Protein Pink1 is Associated with a Poor Response to Chemotherapy and a Poor Prognosis for Patients Treated with Neoadjuvant Chemotherapy for Esophageal Squamous Cell Carcinoma. Ann Surg Oncol. 2017;24:4025-4032 pubmed 出版商

Marks E, Bonnemaison M, Brusnahan S, Zhang W, Fan W, Garrison J, et al. Renal iron accumulation occurs in lupus nephritis and iron chelation delays the onset of albuminuria. Sci Rep. 2017;7:12821 pubmed 出版商

Parisis N, Krasinska L, Harker B, Urbach S, Rossignol M, Camasses A, et al. Initiation of DNA replication requires actin dynamics and formin activity. EMBO J. 2017;36:3212-3231 pubmed 出版商

De Domenico E, Todaro F, Rossi G, Dolci S, Geremia R, Rossi P, et al. Overactive type 2 cannabinoid receptor induces meiosis in fetal gonads and impairs ovarian reserve. Cell Death Dis. 2017;8:e3085 pubmed 出版商

Yang C, Li J, Yu L, Zhang Z, Xu F, Jiang L, et al. Regulation of RIP3 by the transcription factor Sp1 and the epigenetic regulator UHRF1 modulates cancer cell necroptosis. Cell Death Dis. 2017;8:e3084 pubmed 出版商

Huang W, Jin A, Zhang J, Wang C, Tsang L, Cai Z, et al. Upregulation of CFTR in patients with endometriosis and its involvement in NF?B-uPAR dependent cell migration. Oncotarget. 2017;8:66951-66959 pubmed 出版商

Manandhar D, Song L, Kabadi A, Kwon J, Edsall L, Ehrlich M, et al. Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies. Nucleic Acids Res. 2017;45:11684-11699 pubmed 出版商

Keogh N, Chan K, Li G, Lahue R. MutS? abundance and Msh3 ATP hydrolysis activity are important drivers of CTG•CAG repeat expansions. Nucleic Acids Res. 2017;45:10068-10078 pubmed 出版商

Whitfield M, Guiton R, Rispal J, Acar N, Kocer A, Drevet J, et al. Dyslipidemia alters sperm maturation and capacitation in LXR-null mice. Reproduction. 2017;154:827-842 pubmed 出版商

Kushima H, Mori Y, Koshibu M, Hiromura M, Kohashi K, Terasaki M, et al. The role of endothelial nitric oxide in the anti-restenotic effects of liraglutide in a mouse model of restenosis. Cardiovasc Diabetol. 2017;16:122 pubmed 出版商

Qaisiya M, Mardešić P, Pastore B, Tiribelli C, Bellarosa C. The activation of autophagy protects neurons and astrocytes against bilirubin-induced cytotoxicity. Neurosci Lett. 2017;661:96-103 pubmed 出版商

Malone C, Emerson C, Ingraham R, Barbosa W, Guerra S, Yoon H, et al. mTOR and HDAC Inhibitors Converge on the TXNIP/Thioredoxin Pathway to Cause Catastrophic Oxidative Stress and Regression of RAS-Driven Tumors. Cancer Discov. 2017;7:1450-1463 pubmed 出版商

Sargiacomo C, El Kehdy H, Dallmeier K, De Kock J, Hernandez Kelly C, Rogiers V, et al. Upregulation of sodium taurocholate cotransporter polypeptide during hepatogenic differentiation of umbilical cord matrix mesenchymal stem cells facilitates hepatitis B entry. Stem Cell Res Ther. 2017;8:204 pubmed 出版商

Xiao W, Zhao S, Shen F, Liang J, Chen J. Overexpression of CD147 is associated with poor prognosis, tumor cell migration and ERK signaling pathway activation in hepatocellular carcinoma. Exp Ther Med. 2017;14:2637-2642 pubmed 出版商

Bou Samra E, Buhagiar Labarchède G, Machon C, Guitton J, Onclercq Delic R, Green M, et al. A role for Tau protein in maintaining ribosomal DNA stability and cytidine deaminase-deficient cell survival. Nat Commun. 2017;8:693 pubmed 出版商

Herzog V, Reichholf B, Neumann T, Rescheneder P, Bhat P, Burkard T, et al. Thiol-linked alkylation of RNA to assess expression dynamics. Nat Methods. 2017;14:1198-1204 pubmed 出版商

Deng X, Hou C, Wang H, Liang T, Zhu L. Hypermethylation of WIF1 and its inhibitory role in the tumor growth of endometrial adenocarcinoma. Mol Med Rep. 2017;16:7497-7503 pubmed 出版商

Shen Y, Kapfhamer D, Minnella A, Kim J, Won S, Chen Y, et al. Bioenergetic state regulates innate inflammatory responses through the transcriptional co-repressor CtBP. Nat Commun. 2017;8:624 pubmed 出版商

Slemmons K, Crose L, Riedel S, Sushnitha M, Belyea B, Linardic C. A Novel Notch-YAP Circuit Drives Stemness and Tumorigenesis in Embryonal Rhabdomyosarcoma. Mol Cancer Res. 2017;15:1777-1791 pubmed 出版商

Mor D, Tsika E, Mazzulli J, Gould N, Kim H, Daniels M, et al. Dopamine induces soluble α-synuclein oligomers and nigrostriatal degeneration. Nat Neurosci. 2017;20:1560-1568 pubmed 出版商

Miura Y, Kanaho Y. ACAP3, the GTPase-activating protein specific to the small GTPase Arf6, regulates neuronal migration in the developing cerebral cortex. Biochem Biophys Res Commun. 2017;493:1089-1094 pubmed 出版商

Sun J, Ren D. IER3IP1 deficiency leads to increased ?-cell death and decreased ?-cell proliferation. Oncotarget. 2017;8:56768-56779 pubmed 出版商

Karlic H, Haider F, Thaler R, Spitzer S, Klaushofer K, Varga F. Statin and Bisphosphonate Induce Starvation in Fast-Growing Cancer Cell Lines. Int J Mol Sci. 2017;18: pubmed 出版商

Böttcher R, Veelders M, Rombaut P, Faix J, Theodosiou M, Stradal T, et al. Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading. J Cell Biol. 2017;216:3785-3798 pubmed 出版商

Kunde S, Rademacher N, Zieger H, Shoichet S. Protein kinase C regulates AMPA receptor auxiliary protein Shisa9/CKAMP44 through interactions with neuronal scaffold PICK1. FEBS Open Bio. 2017;7:1234-1245 pubmed 出版商

Tang Y, Wang Z, Yang J, Zheng W, Chen D, Wu G, et al. Polycystin-1 inhibits eIF2α phosphorylation and cell apoptosis through a PKR-eIF2α pathway. Sci Rep. 2017;7:11493 pubmed 出版商

Bedau T, Schumacher N, Peters F, Prox J, Arnold P, Koudelka T, et al. Cancer-associated mutations in the canonical cleavage site do not influence CD99 shedding by the metalloprotease meprin β but alter cell migration in vitro. Oncotarget. 2017;8:54873-54888 pubmed 出版商

Kim K, Ruwan Kumara M, Kang K, Piao M, Oh M, Ryu Y, et al. Exposure of keratinocytes to non‑thermal dielectric barrier discharge plasma increases the level of 8‑oxoguanine via inhibition of its repair enzyme. Mol Med Rep. 2017;16:6870-6875 pubmed 出版商

Haspula D, Clark M. MAPK activation patterns of AT1R and CB1R in SHR versus Wistar astrocytes: Evidence of CB1R hypofunction and crosstalk between AT1R and CB1R. Cell Signal. 2017;40:81-90 pubmed 出版商

Dupret B, Volkel P, Vennin C, Toillon R, Le Bourhis X, Angrand P. The histone lysine methyltransferase Ezh2 is required for maintenance of the intestine integrity and for caudal fin regeneration in zebrafish. Biochim Biophys Acta Gene Regul Mech. 2017;1860:1079-1093 pubmed 出版商

Chang C, Kuo C, Ito T, Su Y, Jiang S, Chiu M, et al. CK1? ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation. Proc Natl Acad Sci U S A. 2017;114:E8035-E8044 pubmed 出版商

Kourtidis A, Necela B, Lin W, Lu R, Feathers R, Asmann Y, et al. Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling. J Cell Biol. 2017;216:3073-3085 pubmed 出版商

Wu A, Tymoszuk P, Haschka D, Heeke S, Dichtl S, Petzer V, et al. Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages via Modulation of NF-κB Signaling. Infect Immun. 2017;85: pubmed 出版商

Escoll P, Song O, Viana F, Steiner B, Lagache T, Olivo Marin J, et al. Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages. Cell Host Microbe. 2017;22:302-316.e7 pubmed 出版商

Öztürk E, Despot Slade E, Pichler M, Zenobi Wong M. RhoA activation and nuclearization marks loss of chondrocyte phenotype in crosstalk with Wnt pathway. Exp Cell Res. 2017;360:113-124 pubmed 出版商

Szoka L, Karna E, Hlebowicz Sarat K, Karaszewski J, Boryczka S, Palka J. Acetylenic derivative of betulin induces apoptosis in endometrial adenocarcinoma cell line. Biomed Pharmacother. 2017;95:429-436 pubmed 出版商

Hernández I, Torres Peraza J, Santos Galindo M, Ramos Morón E, Fernandez Fernandez M, Pérez Álvarez M, et al. The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington's disease. Acta Neuropathol. 2017;134:839-850 pubmed 出版商

Liu H, Javaheri A, Godar R, Murphy J, Ma X, Rohatgi N, et al. Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway. Autophagy. 2017;:1-17 pubmed 出版商

Bellio M, Pinto M, Florea V, Barrios P, Taylor C, Brown A, et al. Hypoxic Stress Decreases c-Myc Protein Stability in Cardiac Progenitor Cells Inducing Quiescence and Compromising Their Proliferative and Vasculogenic Potential. Sci Rep. 2017;7:9702 pubmed 出版商

Lessel D, Wu D, Trujillo C, Ramezani T, Lessel I, Alwasiyah M, et al. Dysfunction of the MDM2/p53 axis is linked to premature aging. J Clin Invest. 2017;127:3598-3608 pubmed 出版商

Rong X, Wang B, Palladino E, de Aguiar Vallim T, Ford D, Tontonoz P. ER phospholipid composition modulates lipogenesis during feeding and in obesity. J Clin Invest. 2017;127:3640-3651 pubmed 出版商

Fini M, Gaydos J, McNally A, Karoor V, Burnham E. Alcohol abuse is associated with enhanced pulmonary and systemic xanthine oxidoreductase activity. Am J Physiol Lung Cell Mol Physiol. 2017;313:L1047-L1057 pubmed 出版商

Nelson R, Ya Ping J, Gadbery J, Abedeen D, Sampson N, Lin R, et al. Phospholipase D2 loss results in increased blood pressure via inhibition of the endothelial nitric oxide synthase pathway. Sci Rep. 2017;7:9112 pubmed 出版商

Öztürk E, Hobiger S, Despot Slade E, Pichler M, Zenobi Wong M. Hypoxia regulates RhoA and Wnt/β-catenin signaling in a context-dependent way to control re-differentiation of chondrocytes. Sci Rep. 2017;7:9032 pubmed 出版商

Park J, Byrd A, Lee C, Morgan E. Nitric oxide stimulates cellular degradation of human CYP51A1, the highly conserved lanosterol 14α-demethylase. Biochem J. 2017;474:3241-3252 pubmed 出版商

Warnecke A, Abele S, Musunuri S, Bergquist J, Harris R. Scavenger Receptor A Mediates the Clearance and Immunological Screening of MDA-Modified Antigen by M2-Type Macrophages. Neuromolecular Med. 2017;19:463-479 pubmed 出版商

Liu H, Su D, Zhang J, Ge S, Li Y, Wang F, et al. Improvement of Pharmacokinetic Profile of TRAIL via Trimer-Tag Enhances its Antitumor Activity in vivo. Sci Rep. 2017;7:8953 pubmed 出版商

Benoit T, Valera M, Fontaine C, Buscato M, Lenfant F, Raymond Letron I, et al. Estetrol, a Fetal Selective Estrogen Receptor Modulator, Acts on the Vagina of Mice through Nuclear Estrogen Receptor ? Activation. Am J Pathol. 2017;187:2499-2507 pubmed 出版商

Yu Y, Wang L, Delguste F, Durand A, Guilbaud A, Rousselin C, et al. Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway. Free Radic Biol Med. 2017;112:397-410 pubmed 出版商

Rothschild P, Salah S, Berdugo M, Gélizé E, Delaunay K, Naud M, et al. ROCK-1 mediates diabetes-induced retinal pigment epithelial and endothelial cell blebbing: Contribution to diabetic retinopathy. Sci Rep. 2017;7:8834 pubmed 出版商

Krishnankutty A, Kimura T, Saito T, Aoyagi K, Asada A, Takahashi S, et al. In vivo regulation of glycogen synthase kinase 3β activity in neurons and brains. Sci Rep. 2017;7:8602 pubmed 出版商

Toblli J, Cao G, Giani J, Dominici F, Angerosa M. Markers of oxidative/nitrosative stress and inflammation in lung tissue of rats exposed to different intravenous iron compounds. Drug Des Devel Ther. 2017;11:2251-2263 pubmed 出版商

Wang H, Tang C, Jiang Z, Zhou X, Chen J, Na M, et al. Glutamine promotes Hsp70 and inhibits ?-Synuclein accumulation in pheochromocytoma PC12 cells. Exp Ther Med. 2017;14:1253-1259 pubmed 出版商

Konstantoulas C, Hagen B, Indik S. Moderate sensitivity of mouse mammary tumour virus to inhibition by human APOBEC3G. J Gen Virol. 2017;98:2362-2367 pubmed 出版商

Camerino G, Musumeci O, Conte E, Musaraj K, Fonzino A, Barca E, et al. Risk of Myopathy in Patients in Therapy with Statins: Identification of Biological Markers in a Pilot Study. Front Pharmacol. 2017;8:500 pubmed 出版商

Watanabe R, Fujita N, Sato Y, Kobayashi T, Morita M, Oike T, et al. Enpp1 is an anti-aging factor that regulates Klotho under phosphate overload conditions. Sci Rep. 2017;7:7786 pubmed 出版商

Nio Y, Tanaka M, Hirozane Y, Muraki Y, Okawara M, Hazama M, et al. Phosphodiesterase 4 inhibitor and phosphodiesterase 5 inhibitor combination therapy has antifibrotic and anti-inflammatory effects in mdx mice with Duchenne muscular dystrophy. FASEB J. 2017;31:5307-5320 pubmed 出版商

Poirson J, Biquand E, Straub M, Cassonnet P, Nominé Y, Jones L, et al. Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system. FEBS J. 2017;284:3171-3201 pubmed 出版商

Govaere O, Petz M, Wouters J, Vandewynckel Y, Scott E, Topal B, et al. The PDGFRα-laminin B1-keratin 19 cascade drives tumor progression at the invasive front of human hepatocellular carcinoma. Oncogene. 2017;36:6605-6616 pubmed 出版商

Zaman T, Arimochi H, Maruyama S, Ishifune C, Tsukumo S, Kitamura A, et al. Notch Balances Th17 and Induced Regulatory T Cell Functions in Dendritic Cells by Regulating Aldh1a2 Expression. J Immunol. 2017;199:1989-1997 pubmed 出版商

Stewart S, Menzies S, Popa S, Savinykh N, Petrunkina Harrison A, Lehner P, et al. A genome-wide CRISPR screen reconciles the role of N-linked glycosylation in galectin-3 transport to the cell surface. J Cell Sci. 2017;130:3234-3247 pubmed 出版商

Maekawa S, Sato K, Fujita K, Daigaku R, Tawarayama H, Murayama N, et al. The neuroprotective effect of hesperidin in NMDA-induced retinal injury acts by suppressing oxidative stress and excessive calpain activation. Sci Rep. 2017;7:6885 pubmed 出版商

Yin Y, Li R, Xu K, Ding S, Li J, Baek G, et al. Androgen Receptor Variants Mediate DNA Repair after Prostate Cancer Irradiation. Cancer Res. 2017;77:4745-4754 pubmed 出版商

Porro F, Bortolussi G, Barzel A, De Caneva A, Iaconcig A, Vodret S, et al. Promoterless gene targeting without nucleases rescues lethality of a Crigler-Najjar syndrome mouse model. EMBO Mol Med. 2017;9:1346-1355 pubmed 出版商

Falero Perez J, Park S, Sorenson C, Sheibani N. PEDF expression affects retinal endothelial cell proangiogenic properties through alterations in cell adhesive mechanisms. Am J Physiol Cell Physiol. 2017;313:C405-C420 pubmed 出版商

Mackenzie K, Carroll P, Martin C, Murina O, Fluteau A, Simpson D, et al. cGAS surveillance of micronuclei links genome instability to innate immunity. Nature. 2017;548:461-465 pubmed 出版商

Murray J, Valli E, Yu D, Truong A, Gifford A, Eden G, et al. Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo. Eur J Cancer. 2017;83:132-141 pubmed 出版商

Gagner J, Sarfraz Y, Ortenzi V, Alotaibi F, Chiriboga L, Tayyib A, et al. Multifaceted C-X-C Chemokine Receptor 4 (CXCR4) Inhibition Interferes with Anti-Vascular Endothelial Growth Factor Therapy-Induced Glioma Dissemination. Am J Pathol. 2017;187:2080-2094 pubmed 出版商

Qu J, Qu X, Zhou D. miR‑4262 inhibits colon cancer cell proliferation via targeting of GALNT4. Mol Med Rep. 2017;16:3731-3736 pubmed 出版商

Sutherland L, Thibault P, Durand M, Lapointe E, Knee J, Beauvais A, et al. Splicing arrays reveal novel RBM10 targets, including SMN2 pre-mRNA. BMC Mol Biol. 2017;18:19 pubmed 出版商

Huang C, Xiao X, Yang Y, Mishra A, Liang Y, Zeng X, et al. MicroRNA-101 attenuates pulmonary fibrosis by inhibiting fibroblast proliferation and activation. J Biol Chem. 2017;292:16420-16439 pubmed 出版商

Ishak C, Coschi C, Roes M, Dick F. Disruption of CDK-resistant chromatin association by pRB causes DNA damage, mitotic errors, and reduces Condensin II recruitment. Cell Cycle. 2017;16:1430-1439 pubmed 出版商

Clayton B, Huang A, Kunjamma R, Solanki A, Popko B. The integrated stress response in hypoxia-induced diffuse white matter injury. J Neurosci. 2017;: pubmed 出版商

Ahn M, Hwang J, Ham S, Hur J, Jo Y, Lee S, et al. Subcritical water-hydrolyzed fish collagen ameliorates survival of endotoxemic mice by inhibiting HMGB1 release in a HO-1-dependent manner. Biomed Pharmacother. 2017;93:923-930 pubmed 出版商

Lock F, Babaian A, Zhang Y, Gagnier L, Kuah S, Weberling A, et al. A novel isoform of IL-33 revealed by screening for transposable element promoted genes in human colorectal cancer. PLoS ONE. 2017;12:e0180659 pubmed 出版商

Ilkovičová L, TroÅ¡t N, Szentpéteriová E, Solár P, Komel R, Debeljak N. Overexpression of the erythropoietin receptor in RAMA 37 breast cancer cells alters cell growth and sensitivity to tamoxifen. Int J Oncol. 2017;51:737-746 pubmed 出版商

Favuzzi E, Marques Smith A, Deogracias R, Winterflood C, Sánchez Aguilera A, Mantoan L, et al. Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican. Neuron. 2017;95:639-655.e10 pubmed 出版商

Tschulakow A, Dittmann K, Huber S, Klumpp D, Stegen B, Schraermeyer U, et al. The radioprotector ortho-phospho-L-tyrosine (pTyr) attenuates the side effects of fractionated irradiation in retinoblastoma mouse models but also decreases the local tumour control. Radiother Oncol. 2017;124:462-467 pubmed 出版商

Paulsen E, Kilvaer T, Rakaee M, Richardsen E, Hald S, Andersen S, et al. CTLA-4 expression in the non-small cell lung cancer patient tumor microenvironment: diverging prognostic impact in primary tumors and lymph node metastases. Cancer Immunol Immunother. 2017;66:1449-1461 pubmed 出版商

Bera A, Das F, Ghosh Choudhury N, Mariappan M, Kasinath B, Ghosh Choudhury G. Reciprocal regulation of miR-214 and PTEN by high glucose regulates renal glomerular mesangial and proximal tubular epithelial cell hypertrophy and matrix expansion. Am J Physiol Cell Physiol. 2017;313:C430-C447 pubmed 出版商

Saito S, Maeda R, Adachi N. Dual loss of human POLQ and LIG4 abolishes random integration. Nat Commun. 2017;8:16112 pubmed 出版商

Cook P, Thomas R, Kannan R, de Leon E, Drilon A, Rosenblum M, et al. Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target. Nat Commun. 2017;8:15987 pubmed 出版商

Li X, Wang Q, Hu T, Wang Y, Zhao J, Lu J, et al. A tricyclic antidepressant, amoxapine, reduces amyloid-β generation through multiple serotonin receptor 6-mediated targets. Sci Rep. 2017;7:4983 pubmed 出版商

Senturk J, Bohlman S, Manfredi J. Mdm2 selectively suppresses DNA damage arising from inhibition of topoisomerase II independent of p53. Oncogene. 2017;36:6085-6096 pubmed 出版商

Ramat A, Hannaford M, Januschke J. Maintenance of Miranda Localization in Drosophila Neuroblasts Involves Interaction with the Cognate mRNA. Curr Biol. 2017;27:2101-2111.e5 pubmed 出版商

Uetani N, Hardy S, Gravel S, Kiessling S, Pietrobon A, Wong N, et al. PRL2 links magnesium flux and sex-dependent circadian metabolic rhythms. JCI Insight. 2017;2: pubmed 出版商

Button R, Roberts S, Willis T, Hanemann C, Luo S. Accumulation of autophagosomes confers cytotoxicity. J Biol Chem. 2017;292:13599-13614 pubmed 出版商

Agnihotri P, Robertson N, Umetsu S, Arakcheeva K, Winandy S. Lack of Ikaros cripples expression of Foxo1 and its targets in naive T cells. Immunology. 2017;152:494-506 pubmed 出版商

Nishi K, Luo H, Nakabayashi K, Doi K, Ishikura S, Iwaihara Y, et al. An Alpha-kinase 2 Gene Variant Disrupts Filamentous Actin Localization in the Surface Cells of Colorectal Cancer Spheroids. Anticancer Res. 2017;37:3855-3862 pubmed

Alloatti A, Rookhuizen D, Joannas L, Carpier J, Iborra S, Magalhaes J, et al. Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity. J Exp Med. 2017;214:2231-2241 pubmed 出版商

Biferi M, Cohen Tannoudji M, Cappelletto A, Giroux B, Roda M, Astord S, et al. A New AAV10-U7-Mediated Gene Therapy Prolongs Survival and Restores Function in an ALS Mouse Model. Mol Ther. 2017;25:2038-2052 pubmed 出版商

Beaujean O, Locri F, Aronsson M, Kvanta A, André H. A novel in vivo model of puncture-induced iris neovascularization. PLoS ONE. 2017;12:e0180235 pubmed 出版商

Ngo H, Kim D, Cha Y, Na H, Surh Y. Nrf2 Mutagenic Activation Drives Hepatocarcinogenesis. Cancer Res. 2017;77:4797-4808 pubmed 出版商

Latorre P, Varona L, Burgos C, Carrodeguas J, López Buesa P. O-GlcNAcylation mediates the control of cytosolic phosphoenolpyruvate carboxykinase activity via Pgc1?. PLoS ONE. 2017;12:e0179988 pubmed 出版商

Park J, Lee M, Moon S, Kim J, Ha K, Park E, et al. Scutellaria baicalensis Georgi induces caspase-dependent apoptosis via mitogen activated protein kinase activation and the generation of reactive oxygen species signaling pathways in MCF-7 breast cancer cells. Mol Med Rep. 2017;16:2302-2308 pubmed 出版商

Ning Y, Xu M, Cao X, Chen X, Luo X. Inactivation of AKT, ERK and NF-?B by genistein derivative, 7-difluoromethoxyl-5,4'-di-n-octylygenistein, reduces ovarian carcinoma oncogenicity. Oncol Rep. 2017;38:949-958 pubmed 出版商

Park Y, Seo J, Park J, Lee H, Kim K. Hsp70 acetylation prevents caspase-dependent/independent apoptosis and autophagic cell death in cancer cells. Int J Oncol. 2017;51:573-578 pubmed 出版商

Monteagudo S, Cornelis F, Aznar López C, Yibmantasiri P, Guns L, Carmeliet P, et al. DOT1L safeguards cartilage homeostasis and protects against osteoarthritis. Nat Commun. 2017;8:15889 pubmed 出版商

Rymut S, Corey D, Valerio D, Erokwu B, Flask C, Kelley T, et al. Improved Growth Patterns in Cystic Fibrosis Mice after Loss of Histone Deacetylase 6. Sci Rep. 2017;7:3676 pubmed 出版商

Saito S, Kurosawa A, Adachi N. Mechanistic basis for increased human gene targeting by promoterless vectors-roles of homology arms and Rad54 paralogs. FEBS J. 2017;284:2748-2763 pubmed 出版商

Gliemann L, Rytter N, Lindskrog M, Slingsby M, Akerstrom T, Sylow L, et al. Endothelial mechanotransduction proteins and vascular function are altered by dietary sucrose supplementation in healthy young male subjects. J Physiol. 2017;595:5557-5571 pubmed 出版商

Tapia R, Kralicek S, Hecht G. EPEC effector EspF promotes Crumbs3 endocytosis and disrupts epithelial cell polarity. Cell Microbiol. 2017;19: pubmed 出版商

Heden T, Ryan T, Ferrara P, Hickner R, Brophy P, Neufer P, et al. Greater Oxidative Capacity in Primary Myotubes from Endurance-trained Women. Med Sci Sports Exerc. 2017;49:2151-2157 pubmed 出版商

Alloza I, Goikuria H, Idro J, Triviño J, Fernández Velasco J, Elizagaray E, et al. RNAseq based transcriptomics study of SMCs from carotid atherosclerotic plaque: BMP2 and IDs proteins are crucial regulators of plaque stability. Sci Rep. 2017;7:3470 pubmed 出版商

Cirelli E, De Domenico E, Botti F, Massoud R, Geremia R, Grimaldi P. Effect Of Microgravity On Aromatase Expression In Sertoli Cells. Sci Rep. 2017;7:3469 pubmed 出版商

Boudewyn L, Sikora J, Kuchar L, Ledvinova J, Grishchuk Y, Wang S, et al. N-butyldeoxynojirimycin delays motor deficits, cerebellar microgliosis, and Purkinje cell loss in a mouse model of mucolipidosis type IV. Neurobiol Dis. 2017;105:257-270 pubmed 出版商

Thomas R, Oleinik N, Panneer Selvam S, Vaena S, Dany M, Nganga R, et al. HPV/E7 induces chemotherapy-mediated tumor suppression by ceramide-dependent mitophagy. EMBO Mol Med. 2017;9:1030-1051 pubmed 出版商

Morimura N, Yasuda H, Yamaguchi K, Katayama K, Hatayama M, Tomioka N, et al. Autism-like behaviours and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice. Nat Commun. 2017;8:15800 pubmed 出版商

Weaver B, Weaver Y, Mitani S, Han M. Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development. Dev Cell. 2017;41:665-673.e6 pubmed 出版商

Llobet L, Bayona Bafaluy M, Pacheu Grau D, Torres Perez E, Arbones Mainar J, Navarro M, et al. Pharmacologic concentrations of linezolid modify oxidative phosphorylation function and adipocyte secretome. Redox Biol. 2017;13:244-254 pubmed 出版商

Wyatt L, Xiao W, Americo J, Earl P, Moss B. Novel Nonreplicating Vaccinia Virus Vector Enhances Expression of Heterologous Genes and Suppresses Synthesis of Endogenous Viral Proteins. MBio. 2017;8: pubmed 出版商

Erlandsson M, Töyrä Silfverswärd S, Nadali M, Turkkila M, Svensson M, Jonsson I, et al. IGF-1R signalling contributes to IL-6 production and T cell dependent inflammation in rheumatoid arthritis. Biochim Biophys Acta Mol Basis Dis. 2017;1863:2158-2170 pubmed 出版商

Bassat E, Mutlak Y, Genzelinakh A, Shadrin I, Baruch Umansky K, Yifa O, et al. The extracellular matrix protein agrin promotes heart regeneration in mice. Nature. 2017;547:179-184 pubmed 出版商

Weiner J, Rohde K, Krause K, Zieger K, Kloting N, Kralisch S, et al. Brown adipose tissue (BAT) specific vaspin expression is increased after obesogenic diets and cold exposure and linked to acute changes in DNA-methylation. Mol Metab. 2017;6:482-493 pubmed 出版商

Marks D, Thomas R, Chin Y, Shah R, Khoo C, Benezra R. Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit. Cell Rep. 2017;19:1832-1845 pubmed 出版商

Le Q, Yan B, Yu X, Li Y, Song H, Zhu H, et al. Drug-seeking motivation level in male rats determines offspring susceptibility or resistance to cocaine-seeking behaviour. Nat Commun. 2017;8:15527 pubmed 出版商

Sannino S, Padula M, Managò F, Schaer M, Schneider M, Armando M, et al. Adolescence is the starting point of sex-dichotomous COMT genetic effects. Transl Psychiatry. 2017;7:e1141 pubmed 出版商

King B, Hershkowitz D, Eisenhauer P, Weir M, Ziegler C, Russo J, et al. A Map of the Arenavirus Nucleoprotein-Host Protein Interactome Reveals that Junín Virus Selectively Impairs the Antiviral Activity of Double-Stranded RNA-Activated Protein Kinase (PKR). J Virol. 2017;91: pubmed 出版商

Petkova D, Verlhac P, Rozieres A, Baguet J, Clavière M, Kretz Remy C, et al. Distinct Contributions of Autophagy Receptors in Measles Virus Replication. Viruses. 2017;9: pubmed 出版商

Fernández B, Ferrer I, Gil F, Hilfiker S. Biomonitorization of iron accumulation in the substantia nigra from Lewy body disease patients. Toxicol Rep. 2017;4:188-193 pubmed 出版商

Lutfi E, Riera Heredia N, Córdoba M, Porte C, Gutierrez J, Capilla E, et al. Tributyltin and triphenyltin exposure promotes in vitro adipogenic differentiation but alters the adipocyte phenotype in rainbow trout. Aquat Toxicol. 2017;188:148-158 pubmed 出版商

Szoka L, Karna E, Hlebowicz Sarat K, Karaszewski J, Palka J. Exogenous proline stimulates type I collagen and HIF-1? expression and the process is attenuated by glutamine in human skin fibroblasts. Mol Cell Biochem. 2017;435:197-206 pubmed 出版商

Wongnoppavich A, Dukaew N, Choonate S, Chairatvit K. Upregulation of maspin expression in human cervical carcinoma cells by transforming growth factor β1 through the convergence of Smad and non-Smad signaling pathways. Oncol Lett. 2017;13:3646-3652 pubmed 出版商

Lai Q, Giralt A, Le May C, Zhang L, Cariou B, Denechaud P, et al. E2F1 inhibits circulating cholesterol clearance by regulating Pcsk9 expression in the liver. JCI Insight. 2017;2: pubmed 出版商

Schott M, Rasineni K, Weller S, Schulze R, Sletten A, Casey C, et al. ?-Adrenergic induction of lipolysis in hepatocytes is inhibited by ethanol exposure. J Biol Chem. 2017;292:11815-11828 pubmed 出版商

Tavares S, Vieira A, Taubenberger A, Araújo M, Martins N, Bras Pereira C, et al. Actin stress fiber organization promotes cell stiffening and proliferation of pre-invasive breast cancer cells. Nat Commun. 2017;8:15237 pubmed 出版商

Leitherer S, Clos J, Liebler Tenorio E, Schleicher U, Bogdan C, Soulat D. Characterization of the Protein Tyrosine Phosphatase LmPRL-1 Secreted by Leishmania major via the Exosome Pathway. Infect Immun. 2017;85: pubmed 出版商

Anso E, Weinberg S, Diebold L, Thompson B, Malinge S, Schumacker P, et al. The mitochondrial respiratory chain is essential for haematopoietic stem cell function. Nat Cell Biol. 2017;19:614-625 pubmed 出版商

Donati G, Rognoni E, Hiratsuka T, Liakath Ali K, Hoste E, Kar G, et al. Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties. Nat Cell Biol. 2017;19:603-613 pubmed 出版商

Parent C, Nguyen H, Wen X, Diorio J, Meaney M, Zhang T. Maternal care modulates the febrile response to lipopolysaccharide through differences in glucocorticoid receptor sensitivity in the rat. Brain Behav Immun. 2017;65:239-250 pubmed 出版商

Sakai G, Inoue I, Suzuki T, Sumita T, Inukai K, Katayama S, et al. Effects of the Activation of Three Major Hepatic Akt Substrates on Glucose Metabolism in Male Mice. Endocrinology. 2017;158:2659-2671 pubmed 出版商

Hyun S, Weisberg A, Moss B. Deletion of the Vaccinia Virus I2 Protein Interrupts Virion Morphogenesis, Leading to Retention of the Scaffold Protein and Mislocalization of Membrane-Associated Entry Proteins. J Virol. 2017;91: pubmed 出版商

Spampinato S, Merlo S, Sano Y, Kanda T, Sortino M. Astrocytes contribute to Aβ-induced blood-brain barrier damage through activation of endothelial MMP9. J Neurochem. 2017;142:464-477 pubmed 出版商

Amar F, Sherman M, Rush T, LARSON M, Boyle G, Chang L, et al. The amyloid-β oligomer Aβ*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation. Sci Signal. 2017;10: pubmed 出版商

Lin H, Simon P, Ysla R, Zeichner S, Brewer G, Rabson A. RNA stability regulates human T cell leukemia virus type 1 gene expression in chronically-infected CD4 T cells. Virology. 2017;508:7-17 pubmed 出版商

Cybulsky A, Guillemette J, Papillon J, Abouelazm N. Regulation of Ste20-like kinase, SLK, activity: Dimerization and activation segment phosphorylation. PLoS ONE. 2017;12:e0177226 pubmed 出版商

Isaksen T, Kros L, Vedovato N, Holm T, Vitenzon A, Gadsby D, et al. Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump. PLoS Genet. 2017;13:e1006763 pubmed 出版商

Gao H, Volat F, Sandhow L, Galitzky J, Nguyen T, Estève D, et al. CD36 Is a Marker of Human Adipocyte Progenitors with Pronounced Adipogenic and Triglyceride Accumulation Potential. Stem Cells. 2017;35:1799-1814 pubmed 出版商

Zhang J, Johnson J, He J, Napolitano G, Ramadass M, Rocca C, et al. Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A. J Biol Chem. 2017;292:10328-10346 pubmed 出版商

Ness N, Andersen S, Khanehkenari M, Nordbakken C, Valkov A, Paulsen E, et al. The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort. Oncotarget. 2017;8:26789-26801 pubmed 出版商

Bahl K, Senn J, Yuzhakov O, Bulychev A, Brito L, Hassett K, et al. Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses. Mol Ther. 2017;25:1316-1327 pubmed 出版商

Biegel J, Henderson E, Cox E, Bonenfant G, Netzband R, Kahn S, et al. Cellular DEAD-box RNA helicase DDX6 modulates interaction of miR-122 with the 5' untranslated region of hepatitis C virus RNA. Virology. 2017;507:231-241 pubmed 出版商

Alizadeh A, Dyck S, Kataria H, Shahriary G, Nguyen D, Santhosh K, et al. Neuregulin-1 positively modulates glial response and improves neurological recovery following traumatic spinal cord injury. Glia. 2017;65:1152-1175 pubmed 出版商

Yang H, Xie Y, Yang D, Ren D. Oxidative stress-induced apoptosis in granulosa cells involves JNK, p53 and Puma. Oncotarget. 2017;8:25310-25322 pubmed 出版商

Ashkenazi A, Bento C, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, et al. Polyglutamine tracts regulate beclin 1-dependent autophagy. Nature. 2017;545:108-111 pubmed 出版商

Bastos R, Howard Z, Hiroyasu A, Goodman A. Host and Bacterial Factors Control Susceptibility of Drosophila melanogaster to Coxiella burnetii Infection. Infect Immun. 2017;85: pubmed 出版商

Bradshaw N, Yerabham A, Marreiros R, Zhang T, Nagel Steger L, Korth C. An unpredicted aggregation-critical region of the actin-polymerizing protein TRIOBP-1/Tara, determined by elucidation of its domain structure. J Biol Chem. 2017;292:9583-9598 pubmed 出版商

Kole D, Grella A, Dolivo D, Shumaker L, Hermans W, Dominko T. High molecular weight FGF2 isoforms demonstrate canonical receptor-mediated activity and support human embryonic stem cell self-renewal. Stem Cell Res. 2017;21:106-116 pubmed 出版商

Tang H, Han M. Fatty Acids Regulate Germline Sex Determination through ACS-4-Dependent Myristoylation. Cell. 2017;169:457-469.e13 pubmed 出版商

Kaufman D, Papillon J, Larose L, Iwawaki T, Cybulsky A. Deletion of inositol-requiring enzyme-1? in podocytes disrupts glomerular capillary integrity and autophagy. Mol Biol Cell. 2017;28:1636-1651 pubmed 出版商

Ibarra M, Borini Etichetti C, Di Benedetto C, Rosano G, Margarit E, Del Sal G, et al. Dynamic regulation of Pin1 expression and function during zebrafish development. PLoS ONE. 2017;12:e0175939 pubmed 出版商

Zhang H, Luo J, Alcorn J, Chen K, Fan S, Pilewski J, et al. AIM2 Inflammasome Is Critical for Influenza-Induced Lung Injury and Mortality. J Immunol. 2017;198:4383-4393 pubmed 出版商

Briens A, Bardou I, Lebas H, Miles L, Parmer R, Vivien D, et al. Astrocytes regulate the balance between plasminogen activation and plasmin clearance via cell-surface actin. Cell Discov. 2017;3:17001 pubmed 出版商

Ichihara E, Westover D, Meador C, Yan Y, Bauer J, Lu P, et al. SFK/FAK Signaling Attenuates Osimertinib Efficacy in Both Drug-Sensitive and Drug-Resistant Models of EGFR-Mutant Lung Cancer. Cancer Res. 2017;77:2990-3000 pubmed 出版商

Bailey K, Agarwal E, Chowdhury S, Luo J, Brattain M, Black J, et al. TGF?/Smad3 regulates proliferation and apoptosis through IRS-1 inhibition in colon cancer cells. PLoS ONE. 2017;12:e0176096 pubmed 出版商

Sen R, Kaja A, Ferdoush J, Lahudkar S, Barman P, Bhaumik S. An mRNA Capping Enzyme Targets FACT to the Active Gene To Enhance the Engagement of RNA Polymerase II into Transcriptional Elongation. Mol Cell Biol. 2017;37: pubmed 出版商

Ritter Makinson S, Paquet M, Bogenpohl J, Rodin R, Chris Yun C, Weinman E, et al. Group II metabotropic glutamate receptor interactions with NHERF scaffold proteins: Implications for receptor localization in brain. Neuroscience. 2017;353:58-75 pubmed 出版商

Luna C, Mendoza N, Casao A, Pérez Pé R, Cebrián Pérez J, Muino Blanco T. c-Jun N-terminal kinase and p38 mitogen-activated protein kinase pathways link capacitation with apoptosis and seminal plasma proteins protect sperm by interfering with both routes†. Biol Reprod. 2017;96:800-815 pubmed 出版商

Chen Y, Terajima M, Banerjee P, Guo H, Liu X, Yu J, et al. FKBP65-dependent peptidyl-prolyl isomerase activity potentiates the lysyl hydroxylase 2-driven collagen cross-link switch. Sci Rep. 2017;7:46021 pubmed 出版商

Osier N, Pham L, Pugh B, Puccio A, Ren D, Conley Y, et al. Brain injury results in lower levels of melatonin receptors subtypes MT1 and MT2. Neurosci Lett. 2017;650:18-24 pubmed 出版商

Arce C, Vicente D, Segura V, Flacco N, Montó F, Almenar L, et al. Activation of ?1A -adrenoceptors desensitizes the rat aorta response to phenylephrine through a neuronal NOS pathway, a mechanism lost with ageing. Br J Pharmacol. 2017;174:2015-2030 pubmed 出版商

Giusto M, Barberi L, Di Sario F, Rizzuto E, Nicoletti C, Ascenzi F, et al. Skeletal muscle myopenia in mice model of bile duct ligation and carbon tetrachloride-induced liver cirrhosis. Physiol Rep. 2017;5: pubmed 出版商

Brooks A, Humphreys D, Singh V, Davidson A, Arden S, Buss F, et al. MYO6 is targeted by Salmonella virulence effectors to trigger PI3-kinase signaling and pathogen invasion into host cells. Proc Natl Acad Sci U S A. 2017;114:3915-3920 pubmed 出版商

Otsubo K, Goto H, Nishio M, Kawamura K, Yanagi S, Nishie W, et al. MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation. Oncogene. 2017;36:4201-4211 pubmed 出版商

Zucchelli E, Pema M, Stornaiuolo A, Piovan C, Scavullo C, Giuliani E, et al. Codon Optimization Leads to Functional Impairment of RD114-TR Envelope Glycoprotein. Mol Ther Methods Clin Dev. 2017;4:102-114 pubmed 出版商

Vodret S, Bortolussi G, Jašprová J, Vitek L, Muro A. Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 -/- mouse model. J Neuroinflammation. 2017;14:64 pubmed 出版商

Sakai T, Miyazaki T, Shin D, Kim Y, Qi C, Fariss R, et al. DNase-active TREX1 frame-shift mutants induce serologic autoimmunity in mice. J Autoimmun. 2017;81:13-23 pubmed 出版商

Dijk W, Mattijssen F, de la Rosa Rodriguez M, Loza Valdes A, Loft A, Mandrup S, et al. Hypoxia-Inducible Lipid Droplet-Associated Is Not a Direct Physiological Regulator of Lipolysis in Adipose Tissue. Endocrinology. 2017;158:1231-1251 pubmed 出版商

Marcassa E, Raimondi M, Anwar T, Eskelinen E, Myers M, Triolo G, et al. Calpain mobilizes Atg9/Bif-1 vesicles from Golgi stacks upon autophagy induction by thapsigargin. Biol Open. 2017;6:551-562 pubmed 出版商

Jin Z, Liang F, Yang J, Mei W. hnRNP I regulates neonatal immune adaptation and prevents colitis and colorectal cancer. PLoS Genet. 2017;13:e1006672 pubmed 出版商

Kralova J, Kolar M, Kahle M, Truksa J, Lettlova S, Balusikova K, et al. Glycol porphyrin derivatives and temoporfin elicit resistance to photodynamic therapy by different mechanisms. Sci Rep. 2017;7:44497 pubmed 出版商

Garofalo S, Grimaldi A, Chece G, Porzia A, Morrone S, Mainiero F, et al. The Glycoside Oleandrin Reduces Glioma Growth with Direct and Indirect Effects on Tumor Cells. J Neurosci. 2017;37:3926-3939 pubmed 出版商

Jing X, Sui W, Wang S, Xu X, Yuan R, Chen X, et al. HDAC7 Ubiquitination by the E3 Ligase CBX4 Is Involved in Contextual Fear Conditioning Memory Formation. J Neurosci. 2017;37:3848-3863 pubmed 出版商

Fajardo V, Gamu D, Mitchell A, Bloemberg D, Bombardier E, Chambers P, et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS ONE. 2017;12:e0173708 pubmed 出版商

Arnold P, Boll I, Rothaug M, Schumacher N, Schmidt F, Wichert R, et al. Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling. Sci Rep. 2017;7:44053 pubmed 出版商

Boswell S, Snavely A, Landry H, Churchman L, Gray J, Springer M. Total RNA-seq to identify pharmacological effects on specific stages of mRNA synthesis. Nat Chem Biol. 2017;13:501-507 pubmed 出版商

Lu J, Li X, Wang Q, Pei G. Dopamine D2 receptor and β-arrestin 2 mediate Amyloid-β elevation induced by anti-parkinson's disease drugs, levodopa and piribedil, in neuronal cells. PLoS ONE. 2017;12:e0173240 pubmed 出版商

Ozaki R, Kuroda K, Ikemoto Y, Ochiai A, Matsumoto A, Kumakiri J, et al. Reprogramming of the retinoic acid pathway in decidualizing human endometrial stromal cells. PLoS ONE. 2017;12:e0173035 pubmed 出版商

Ho T, Warr M, Adelman E, Lansinger O, Flach J, Verovskaya E, et al. Autophagy maintains the metabolism and function of young and old stem cells. Nature. 2017;543:205-210 pubmed 出版商

Ben Yaacov A, Gillor M, Haham T, Parsai A, Qneibi M, Stern Bach Y. Molecular Mechanism of AMPA Receptor Modulation by TARP/Stargazin. Neuron. 2017;93:1126-1137.e4 pubmed 出版商

Chen W, Ren Y, Ren J, Erxleben C, Johnson M, Gentile S, et al. (+)-Strebloside-Induced Cytotoxicity in Ovarian Cancer Cells Is Mediated through Cardiac Glycoside Signaling Networks. J Nat Prod. 2017;80:659-669 pubmed 出版商

Marinaro F, Marzi M, Hoffmann N, Amin H, Pelizzoli R, Niola F, et al. MicroRNA-independent functions of DGCR8 are essential for neocortical development and TBR1 expression. EMBO Rep. 2017;18:603-618 pubmed 出版商

El Shazly A, Roncarati P, Lejeune M, Lefebvre P, Delvenne P. Tyrosine kinase inhibition is an important factor for gene expression of CRTH2 in human eosinophils and lymphocytes: A novel mechanism for explaining eosinophils recruitment by the neuro-immune axis in allergic rhinitis. Int Immunopharmacol. 2017;45:180-186 pubmed 出版商

Schulze U, Vollenbröker B, Kühnl A, Granado D, Bayraktar S, Rescher U, et al. Cellular vacuolization caused by overexpression of the PIKfyve-binding deficient Vac14L156R is rescued by starvation and inhibition of vacuolar-ATPase. Biochim Biophys Acta Mol Cell Res. 2017;1864:749-759 pubmed 出版商

Ismail M, Mateos L, Maioli S, Merino Serrais P, Ali Z, Lodeiro M, et al. 27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation. J Exp Med. 2017;214:699-717 pubmed 出版商

Kim K, Park S, Kim J, Lee S, Kim D, Koo T, et al. Genome surgery using Cas9 ribonucleoproteins for the treatment of age-related macular degeneration. Genome Res. 2017;27:419-426 pubmed 出版商

Compagno M, Wang Q, Pighi C, Cheong T, Meng F, Poggio T, et al. Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells. Nature. 2017;542:489-493 pubmed 出版商

Gupta R, Lan M, Mojsilovic Petrovic J, Choi W, Safren N, Barmada S, et al. The Proline/Arginine Dipeptide from Hexanucleotide Repeat Expanded C9ORF72 Inhibits the Proteasome. Eneuro. 2017;4: pubmed 出版商

Wang J, Rajbhandari P, Damianov A, Han A, Sallam T, Waki H, et al. RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs. J Clin Invest. 2017;127:987-1004 pubmed 出版商

Diao Z, Asico L, Villar V, Zheng X, Cuevas S, Armando I, et al. Increased renal oxidative stress in salt-sensitive human GRK4γ486V transgenic mice. Free Radic Biol Med. 2017;106:80-90 pubmed 出版商

Lee H, Lee D, Mariappan M, Feliers D, Ghosh Choudhury G, Abboud H, et al. Hydrogen sulfide inhibits high glucose-induced NADPH oxidase 4 expression and matrix increase by recruiting inducible nitric oxide synthase in kidney proximal tubular epithelial cells. J Biol Chem. 2017;292:5665-5675 pubmed 出版商

Lang S, Harre U, Purohit P, Dietel K, Kienhöfer D, Hahn J, et al. Neurodegeneration Enhances the Development of Arthritis. J Immunol. 2017;198:2394-2402 pubmed 出版商

Fielding C, Weekes M, Nobre L, Růcková E, Wilkie G, Paulo J, et al. Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation. elife. 2017;6: pubmed 出版商

Lertsuwan K, Choe L, Marwa I, Lee K, Sikes R. Identification of Fibulin-1 as a Human Bone Marrow Stromal (HS-5) Cell-Derived Factor That Induces Human Prostate Cancer Cell Death. Prostate. 2017;77:729-742 pubmed 出版商

Lundby C, Montero D, Gehrig S, Andersson Hall U, Kaiser P, Boushel R, et al. Physiological, biochemical, anthropometric, and biomechanical influences on exercise economy in humans. Scand J Med Sci Sports. 2017;27:1627-1637 pubmed 出版商

Taniguchi K, Moroishi T, de Jong P, Krawczyk M, Grebbin B, Luo H, et al. YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis. Proc Natl Acad Sci U S A. 2017;114:1643-1648 pubmed 出版商

Kissing S, Rudnik S, Damme M, Lüllmann Rauch R, Ichihara A, Kornak U, et al. Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes. Autophagy. 2017;13:670-685 pubmed 出版商

Verma K, Datta S. The Monomeric GTPase Rab35 Regulates Phagocytic Cup Formation and Phagosomal Maturation in Entamoeba histolytica. J Biol Chem. 2017;292:4960-4975 pubmed 出版商

Furusawa K, Asada A, Urrutia P, Gonzalez Billault C, Fukuda M, Hisanaga S. Cdk5 Regulation of the GRAB-Mediated Rab8-Rab11 Cascade in Axon Outgrowth. J Neurosci. 2017;37:790-806 pubmed 出版商

Macmillan L, Lamarre S, daSilva R, Jacobs R, Brosnan M, Brosnan J. Riboflavin Deficiency in Rats Decreases de novo Formate Production but Does Not Affect Plasma Formate Concentration. J Nutr. 2017;147:346-352 pubmed 出版商

Dráberová E, Sulimenko V, Vinopal S, Sulimenko T, Sladkova V, D Agostino L, et al. Differential expression of human ?-tubulin isotypes during neuronal development and oxidative stress points to a ?-tubulin-2 prosurvival function. FASEB J. 2017;31:1828-1846 pubmed 出版商

Pleasant Jenkins D, Reese C, Chinnakkannu P, Kasiganesan H, Tourkina E, Hoffman S, et al. Reversal of maladaptive fibrosis and compromised ventricular function in the pressure overloaded heart by a caveolin-1 surrogate peptide. Lab Invest. 2017;97:370-382 pubmed 出版商

Cesarini V, Martini M, Vitiani L, Gravina G, Di Agostino S, Graziani G, et al. Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome. Oncotarget. 2017;8:13223-13239 pubmed 出版商

Waxse B, Sengupta P, Hesketh G, Lippincott Schwartz J, Buss F. Myosin VI facilitates connexin 43 gap junction accretion. J Cell Sci. 2017;130:827-840 pubmed 出版商

Sherman M, Yu R, Tseng T, Sousa C, Liu S, Truitt M, et al. Stromal cues regulate the pancreatic cancer epigenome and metabolome. Proc Natl Acad Sci U S A. 2017;114:1129-1134 pubmed 出版商

Zhang S, Eitan E, Mattson M. Early involvement of lysosome dysfunction in the degeneration of cerebral cortical neurons caused by the lipid peroxidation product 4-hydroxynonenal. J Neurochem. 2017;140:941-954 pubmed 出版商

Phua S, Chiba S, Suzuki M, Su E, Roberson E, Pusapati G, et al. Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision. Cell. 2017;168:264-279.e15 pubmed 出版商

Shang P, Valapala M, Grebe R, Hose S, Ghosh S, Bhutto I, et al. The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling. Aging Cell. 2017;16:349-359 pubmed 出版商

Cianciola N, Chung S, Manor D, Carlin C. Adenovirus Modulates Toll-Like Receptor 4 Signaling by Reprogramming ORP1L-VAP Protein Contacts for Cholesterol Transport from Endosomes to the Endoplasmic Reticulum. J Virol. 2017;91: pubmed 出版商

Huang S, Mao J, Ding K, Zhou Y, Zeng X, Yang W, et al. Polysaccharides from Ganoderma lucidum Promote Cognitive Function and Neural Progenitor Proliferation in Mouse Model of Alzheimer's Disease. Stem Cell Reports. 2017;8:84-94 pubmed 出版商