产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
产品类型 :
抗体
产品名称 :
Monoclonal Anti-Actin, α-Smooth Muscle
目录 :
A2547
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
1A4
反应物种 :
common marmoset, 人类, 小鼠, 大鼠, , , , pigs , fruit fly , 家羊, domestic rabbit, 国内马
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 其他, 免疫细胞化学基因敲除验证
更多信息或购买 :
文章摘录数: 1609
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 1d
Lechertier T, Reynolds L, Kim H, Pedrosa A, Gómez Escudero J, Muñoz Félix J, et al. Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth. Nat Commun. 2020;11:2810 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 6f
Somerville T, Biffi G, Da ler Plenker J, Hur S, He X, Vance K, et al. Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation. elife. 2020;9: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 7
  • 免疫印迹; 小鼠; 1:250; 图 7g, h
Gremlich S, Roth Kleiner M, Equey L, Fytianos K, Schittny J, Cremona T. Tenascin-C inactivation impacts lung structure and function beyond lung development. Sci Rep. 2020;10:5118 pubmed 出版商
  • 免疫组化-石蜡切片; domestic rabbit; 1:500; 图 4a
Meier Bürgisser G, Evrova O, Calcagni M, Scalera C, Giovanoli P, Buschmann J. Impact of PDGF-BB on cellular distribution and extracellular matrix in the healing rabbit Achilles tendon three weeks post-operation. FEBS Open Bio. 2020;10:327-337 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 s8c, s9c
Mantani P, Dunér P, Ljungcrantz I, Nilsson J, Bjorkbacka H, Fredrikson G. ILC2 transfers to apolipoprotein E deficient mice reduce the lipid content of atherosclerotic lesions. BMC Immunol. 2019;20:47 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 4h, s3j, s6f
Yung T, Poon F, Liang M, Coquenlorge S, McGaugh E, Hui C, et al. Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals. Nat Commun. 2019;10:4647 pubmed 出版商
  • 免疫印迹; 人类; 图 5c
Ren J, Smid M, Iaria J, Salvatori D, van Dam H, Zhu H, et al. Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression. Breast Cancer Res. 2019;21:109 pubmed 出版商
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Cibi D, Mia M, Guna Shekeran S, Yun L, Sandireddy R, Gupta P, et al. Neural crest-specific deletion of Rbfox2 in mice leads to craniofacial abnormalities including cleft palate. elife. 2019;8: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4f
Wen H, Gao S, Wang Y, Ray M, Magnuson M, Wright C, et al. Myeloid cell-derived HB-EGF Drives Tissue Recovery After Pancreatitis. Cell Mol Gastroenterol Hepatol. 2019;: pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 4c26
An S, Raju I, Surenkhuu B, Kwon J, Gulati S, Karaman M, et al. Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies. Ocul Surf. 2019;: pubmed 出版商
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Farbehi N, Patrick R, Dorison A, Xaymardan M, Janbandhu V, Wystub Lis K, et al. Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3b
Wu W, Zhang W, Choi M, Zhao J, Gao P, Xue M, et al. Vascular smooth muscle-MAPK14 is required for neointimal hyperplasia by suppressing VSMC differentiation and inducing proliferation and inflammation. Redox Biol. 2019;22:101137 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:400; 图 s5c
Sahara M, Santoro F, Sohlmér J, Zhou C, Witman N, Leung C, et al. Population and Single-Cell Analysis of Human Cardiogenesis Reveals Unique LGR5 Ventricular Progenitors in Embryonic Outflow Tract. Dev Cell. 2019;48:475-490.e7 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1i
Wimmer R, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, et al. Human blood vessel organoids as a model of diabetic vasculopathy. Nature. 2019;565:505-510 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 2g
Mahmoud M, Evans I, Mehta V, Pellet Many C, Paliashvili K, Zachary I. Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation. Am J Physiol Cell Physiol. 2019;316:C424-C433 pubmed 出版商
  • 免疫组化; 小鼠; 图 s4e
Quitterer U, Fu X, Pohl A, Bayoumy K, Langer A, AbdAlla S. Beta-Arrestin1 Prevents Preeclampsia by Downregulation of Mechanosensitive AT1-B2 Receptor Heteromers. Cell. 2019;176:318-333.e19 pubmed 出版商
  • 免疫组化; 人类; 1:200; 图 1c
Weltner J, Balboa D, Katayama S, Bespalov M, Krjutskov K, Jouhilahti E, et al. Human pluripotent reprogramming with CRISPR activators. Nat Commun. 2018;9:2643 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 s4b
García Nores G, Ly C, Cuzzone D, Kataru R, Hespe G, Torrisi J, et al. CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema. Nat Commun. 2018;9:1970 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:2500
Rickelt S, Hynes R. Antibodies and methods for immunohistochemistry of extracellular matrix proteins. Matrix Biol. 2018;71-72:10-27 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 8a
Ho L, Skiba N, Ullmer C, Rao P. Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2018;59:1969-1984 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:200; 图 11c
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 2c
  • 免疫细胞化学; 小鼠; 1:200; 图 5f
Fu X, Khalil H, Kanisicak O, Boyer J, Vagnozzi R, Maliken B, et al. Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart. J Clin Invest. 2018;128:2127-2143 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:600; 图 8a
Nofi C, Bogatyryov Y, Dedkov E. Preservation of Functional Microvascular Bed Is Vital for Long-Term Survival of Cardiac Myocytes Within Large Transmural Post-Myocardial Infarction Scar. J Histochem Cytochem. 2017;:22155417741640 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 2d
Van T, Polykratis A, Straub B, Kondylis V, Papadopoulou N, Pasparakis M. Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. J Clin Invest. 2017;127:2662-2677 pubmed 出版商
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Xia H, Gilbertsen A, Herrera J, Racila E, Smith K, Peterson M, et al. Calcium-binding protein S100A4 confers mesenchymal progenitor cell fibrogenicity in idiopathic pulmonary fibrosis. J Clin Invest. 2017;127:2586-2597 pubmed 出版商
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Tian H, Ketova T, Hardy D, Xu X, Gao X, Zijlstra A, et al. Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading. Arterioscler Thromb Vasc Biol. 2017;37:1115-1126 pubmed 出版商
  • 免疫印迹; 人类; 图 4c
Li P, Wang Y, Mao X, Jiang Y, Liu J, Li J, et al. CRB3 downregulation confers breast cancer stem cell traits through TAZ/?-catenin. Oncogenesis. 2017;6:e322 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 s2d
Qi W, Keenan H, Li Q, Ishikado A, Kannt A, Sadowski T, et al. Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction. Nat Med. 2017;23:753-762 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3b
  • 免疫印迹; 小鼠; 1:1000; 图 3c
Gerarduzzi C, Kumar R, Trivedi P, Ajay A, Iyer A, Boswell S, et al. Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation. JCI Insight. 2017;2: pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Menicacci B, Laurenzana A, Chillà A, Margheri F, Peppicelli S, Tanganelli E, et al. Chronic Resveratrol Treatment Inhibits MRC5 Fibroblast SASP-Related Protumoral Effects on Melanoma Cells. J Gerontol A Biol Sci Med Sci. 2017;72:1187-1195 pubmed 出版商
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Barry C, Ji E, Sharma H, Beukes L, Vilimas P, Degraaf Y, et al. Morphological and neurochemical differences in peptidergic nerve fibers of the mouse vagina. J Comp Neurol. 2017;525:2394-2410 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5e
Arioka Y, Ito H, Hirata A, Semi K, Yamada Y, Seishima M. Behavior of leucine-rich repeat-containing G-protein coupled receptor 5-expressing cells in the reprogramming process. Stem Cell Res. 2017;20:1-9 pubmed 出版商
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Schatton D, Pla Martín D, Marx M, Hansen H, Mourier A, Nemazanyy I, et al. CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. 2017;216:675-693 pubmed 出版商
  • 免疫组化; 小鼠; 图 2e
Lovric S, Gonçalves S, Gee H, Oskouian B, Srinivas H, Choi W, et al. Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency. J Clin Invest. 2017;127:912-928 pubmed 出版商
  • 免疫组化; 大鼠; 1:100; 图 3a
  • 免疫印迹; 大鼠; 1:2000; 图 2a
Shu D, Wojciechowski M, Lovicu F. Bone Morphogenetic Protein-7 Suppresses TGF?2-Induced Epithelial-Mesenchymal Transition in the Lens: Implications for Cataract Prevention. Invest Ophthalmol Vis Sci. 2017;58:781-796 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2f
Xu J, Zhu S, Heng B, Dissanayaka W, Zhang C. TGF-?1-induced differentiation of SHED into functional smooth muscle cells. Stem Cell Res Ther. 2017;8:10 pubmed 出版商
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Gopal S, Veracini L, Grall D, Butori C, Schaub S, Audebert S, et al. Fibronectin-guided migration of carcinoma collectives. Nat Commun. 2017;8:14105 pubmed 出版商
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Benito Jardón M, Klapproth S, Gimeno LLuch I, Petzold T, Bharadwaj M, Müller D, et al. The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes. elife. 2017;6: pubmed 出版商
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de Jong R, Paulin N, Lemnitzer P, Viola J, Winter C, Ferraro B, et al. Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report. Arterioscler Thromb Vasc Biol. 2017;37:312-315 pubmed 出版商
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Hosoya M, Fujioka M, Sone T, Okamoto S, Akamatsu W, Ukai H, et al. Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss. Cell Rep. 2017;18:68-81 pubmed 出版商
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Yang J, Savvatis K, Kang J, Fan P, Zhong H, Schwartz K, et al. Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment. Nat Commun. 2016;7:13710 pubmed 出版商
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Hofmann K, Fiedler S, Vierkotten S, Weber J, Klee S, Jia J, et al. Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis. Biochim Biophys Acta Mol Basis Dis. 2017;1863:560-568 pubmed 出版商
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Tian S, Li C, Ran R, Chen S. Surfactant protein A deficiency exacerbates renal interstitial fibrosis following obstructive injury in mice. Biochim Biophys Acta Mol Basis Dis. 2017;1863:509-517 pubmed 出版商
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Goreczny G, Ouderkirk Pecone J, Olson E, Krendel M, Turner C. Hic-5 remodeling of the stromal matrix promotes breast tumor progression. Oncogene. 2017;36:2693-2703 pubmed 出版商
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Herring A, Messana A, Bara A, Hazelbaker D, Eggan K, Barrett L. Generation of a TLE1 homozygous knockout human embryonic stem cell line using CRISPR-Cas9. Stem Cell Res. 2016;17:430-432 pubmed 出版商
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Keshri G, Gupta A, Yadav A, Sharma S, Singh S. Photobiomodulation with Pulsed and Continuous Wave Near-Infrared Laser (810 nm, Al-Ga-As) Augments Dermal Wound Healing in Immunosuppressed Rats. PLoS ONE. 2016;11:e0166705 pubmed 出版商
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Grootaert M, Schrijvers D, Hermans M, Van Hoof V, De Meyer G, Martinet W. Caspase-3 Deletion Promotes Necrosis in Atherosclerotic Plaques of ApoE Knockout Mice. Oxid Med Cell Longev. 2016;2016:3087469 pubmed
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Sizemore G, Balakrishnan S, Hammer A, Thies K, Trimboli A, Wallace J, et al. Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1. Oncogene. 2017;36:2297-2308 pubmed 出版商
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Han J, Bae J, Choi C, Choi S, Kang H, Jo E, et al. Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice. Autophagy. 2016;12:2326-2343 pubmed
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Chiche A, Moumen M, Romagnoli M, Petit V, Lasla H, Jézéquel P, et al. p53 deficiency induces cancer stem cell pool expansion in a mouse model of triple-negative breast tumors. Oncogene. 2017;36:2355-2365 pubmed 出版商
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Nguyen H, Kirkton R, Bursac N. Engineering prokaryotic channels for control of mammalian tissue excitability. Nat Commun. 2016;7:13132 pubmed 出版商
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Che D, Zhou T, Lan Y, Xie J, Gong H, Li C, et al. High glucose-induced epithelial-mesenchymal transition contributes to the upregulation of fibrogenic factors in retinal pigment epithelial cells. Int J Mol Med. 2016;38:1815-1822 pubmed 出版商
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Ta M, Schwensen K, Foster S, Korgaonkar M, Ozimek Kulik J, Phillips J, et al. Effects of TORC1 Inhibition during the Early and Established Phases of Polycystic Kidney Disease. PLoS ONE. 2016;11:e0164193 pubmed 出版商
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Gupta S, Zeglinski M, Rattan S, Landry N, Ghavami S, Wigle J, et al. Inhibition of autophagy inhibits the conversion of cardiac fibroblasts to cardiac myofibroblasts. Oncotarget. 2016;7:78516-78531 pubmed 出版商
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Liu Y, Wang T, Zhang R, Fu W, Wang X, Wang F, et al. Calorie restriction protects against experimental abdominal aortic aneurysms in mice. J Exp Med. 2016;213:2473-2488 pubmed
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Chen P, Qin L, Li G, Tellides G, Simons M. Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGF?)-dependent smooth muscle cell phenotype modulation. Sci Rep. 2016;6:33407 pubmed 出版商
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Jurek A, Genander M, Kundu P, Catchpole T, He X, Strååt K, et al. Eph receptor interclass cooperation is required for the regulation of cell proliferation. Exp Cell Res. 2016;348:10-22 pubmed 出版商
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Görtz G, Moshkelgosha S, Jesenek C, Edelmann B, Horstmann M, Banga J, et al. Pathogenic Phenotype of Adipogenesis and Hyaluronan in Orbital Fibroblasts From Female Graves' Orbitopathy Mouse Model. Endocrinology. 2016;157:3771-3778 pubmed
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Riascos Bernal D, Chinnasamy P, Cao L, Dunaway C, Valenta T, Basler K, et al. β-Catenin C-terminal signals suppress p53 and are essential for artery formation. Nat Commun. 2016;7:12389 pubmed 出版商
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Medrano J, Rombaut C, Simon C, Pellicer A, Goossens E. Human spermatogonial stem cells display limited proliferation in vitro under mouse spermatogonial stem cell culture conditions. Fertil Steril. 2016;106:1539-1549.e8 pubmed 出版商
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Kaukonen R, Mai A, Georgiadou M, Saari M, De Franceschi N, Betz T, et al. Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. Nat Commun. 2016;7:12237 pubmed 出版商
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Ta M, Schwensen K, Liuwantara D, Huso D, Watnick T, Rangan G. Constitutive renal Rel/nuclear factor-?B expression in Lewis polycystic kidney disease rats. World J Nephrol. 2016;5:339-57 pubmed 出版商
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Dauleh S, Santeramo I, Fielding C, Ward K, Herrmann A, Murray P, et al. Characterisation of Cultured Mesothelial Cells Derived from the Murine Adult Omentum. PLoS ONE. 2016;11:e0158997 pubmed 出版商
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Yu Q, Song W, Wang D, Zeng Y. Identification of blood vascular endothelial stem cells by the expression of protein C receptor. Cell Res. 2016;26:1079-1098 pubmed 出版商
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Kim J, Hong S, Park C, Park J, Choi S, Woo S, et al. Intramyocardial Adipose-Derived Stem Cell Transplantation Increases Pericardial Fat with Recovery of Myocardial Function after Acute Myocardial Infarction. PLoS ONE. 2016;11:e0158067 pubmed 出版商
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Barrionuevo F, Hurtado A, Kim G, Real F, Bakkali M, Kopp J, et al. Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration. elife. 2016;5: pubmed 出版商
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Muñoz Félix J, Pérez Roque L, Núñez Gómez E, Oujo B, Arevalo M, Ruiz Remolina L, et al. Overexpression of the short endoglin isoform reduces renal fibrosis and inflammation after unilateral ureteral obstruction. Biochim Biophys Acta. 2016;1862:1801-14 pubmed 出版商
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Lin W, Lim S, Yen T, Alison M. The Influence of Bone Marrow-Secreted IL-10 in a Mouse Model of Cerulein-Induced Pancreatic Fibrosis. Biomed Res Int. 2016;2016:4601532 pubmed 出版商
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Zaglia T, Di Bona A, Chioato T, Basso C, Ausoni S, Mongillo M. Optimized protocol for immunostaining of experimental GFP-expressing and human hearts. Histochem Cell Biol. 2016;146:407-19 pubmed 出版商
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Kobayashi K, Araya J, Minagawa S, Hara H, Saito N, Kadota T, et al. Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis. J Immunol. 2016;197:504-16 pubmed 出版商
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Farrugia A, Calvo F. Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts. Small Gtpases. 2017;8:49-57 pubmed 出版商
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Puchert M, Adams V, Linke A, Engele J. Evidence for the involvement of the CXCL12 system in the adaptation of skeletal muscles to physical exercise. Cell Signal. 2016;28:1205-15 pubmed 出版商
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Katanov C, Lerrer S, Liubomirski Y, Leider Trejo L, Meshel T, Bar J, et al. Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF-? and the NF-?B pathway. Stem Cell Res Ther. 2015;6:87 pubmed 出版商
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Yongping M, Zhang X, Xuewei L, Fan W, Chen J, Zhang H, et al. Astragaloside prevents BDL-induced liver fibrosis through inhibition of notch signaling activation. J Ethnopharmacol. 2015;169:200-9 pubmed 出版商
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Dayer C, Stamenkovic I. Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-β (TGF-β) Activation and Fibroblast Differentiation. J Biol Chem. 2015;290:13763-78 pubmed 出版商
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Otsuki S, Sawada H, Yodoya N, Shinohara T, Kato T, Ohashi H, et al. Potential contribution of phenotypically modulated smooth muscle cells and related inflammation in the development of experimental obstructive pulmonary vasculopathy in rats. PLoS ONE. 2015;10:e0118655 pubmed 出版商
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Fritz A, Adil M, Mao S, Schaffer D. cAMP and EPAC Signaling Functionally Replace OCT4 During Induced Pluripotent Stem Cell Reprogramming. Mol Ther. 2015;23:952-963 pubmed 出版商
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Gallos G, Yocum G, Siviski M, Yim P, Fu X, Poe M, et al. Selective targeting of the α5-subunit of GABAA receptors relaxes airway smooth muscle and inhibits cellular calcium handling. Am J Physiol Lung Cell Mol Physiol. 2015;308:L931-42 pubmed 出版商
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Afzal M, Strande J. Generation of induced pluripotent stem cells from muscular dystrophy patients: efficient integration-free reprogramming of urine derived cells. J Vis Exp. 2015;:52032 pubmed 出版商
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Yang L, Hu J, Hao H, Yin Z, Liu G, Zou X. Sodium tanshinone IIA sulfonate attenuates the transforming growth factor-β1-induced differentiation of atrial fibroblasts into myofibroblasts in vitro. Int J Mol Med. 2015;35:1026-32 pubmed 出版商
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Shapero K, Wylie Sears J, Levine R, Mayer J, Bischoff J. Reciprocal interactions between mitral valve endothelial and interstitial cells reduce endothelial-to-mesenchymal transition and myofibroblastic activation. J Mol Cell Cardiol. 2015;80:175-85 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1A
  • 免疫印迹; 人类; 图 2A
Bárcena C, Stefanovic M, Tutusaus A, Martinez Nieto G, Martinez L, García Ruiz C, et al. Angiogenin secretion from hepatoma cells activates hepatic stellate cells to amplify a self-sustained cycle promoting liver cancer. Sci Rep. 2015;5:7916 pubmed 出版商
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Malhotra R, Burke M, Martyn T, Shakartzi H, Thayer T, O Rourke C, et al. Inhibition of bone morphogenetic protein signal transduction prevents the medial vascular calcification associated with matrix Gla protein deficiency. PLoS ONE. 2015;10:e0117098 pubmed 出版商
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Coutelle O, Schiffmann L, Liwschitz M, Brunold M, Goede V, Hallek M, et al. Dual targeting of Angiopoetin-2 and VEGF potentiates effective vascular normalisation without inducing empty basement membrane sleeves in xenograft tumours. Br J Cancer. 2015;112:495-503 pubmed 出版商
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Kalwa H, Storch U, Demleitner J, Fiedler S, Mayer T, Kannler M, et al. Phospholipase C epsilon (PLCε) induced TRPC6 activation: a common but redundant mechanism in primary podocytes. J Cell Physiol. 2015;230:1389-99 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:4000; 表 2
Ta M, Rao P, Korgaonkar M, Foster S, Peduto A, Harris D, et al. Pyrrolidine dithiocarbamate reduces the progression of total kidney volume and cyst enlargement in experimental polycystic kidney disease. Physiol Rep. 2014;2: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:30000
Vogels R, Vlenterie M, Versleijen Jonkers Y, Ruijter E, Bekers E, Verdijk M, et al. Solitary fibrous tumor - clinicopathologic, immunohistochemical and molecular analysis of 28 cases. Diagn Pathol. 2014;9:224 pubmed 出版商
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O Hara L, McInnes K, Simitsidellis I, Morgan S, Atanassova N, Slowikowska Hilczer J, et al. Autocrine androgen action is essential for Leydig cell maturation and function, and protects against late-onset Leydig cell apoptosis in both mice and men. FASEB J. 2015;29:894-910 pubmed 出版商
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Barnes M, McMullen M, Roychowdhury S, Madhun N, Niese K, Olman M, et al. Macrophage migration inhibitory factor is required for recruitment of scar-associated macrophages during liver fibrosis. J Leukoc Biol. 2015;97:161-9 pubmed 出版商
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Macías D, Fernández Agüera M, Bonilla Henao V, López Barneo J. Deletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia. EMBO Mol Med. 2014;6:1577-92 pubmed 出版商
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Taniguchi T, Asano Y, Akamata K, Noda S, Takahashi T, Ichimura Y, et al. Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated Fli-1-haploinsufficient mice. Arthritis Rheumatol. 2015;67:517-26 pubmed 出版商
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Moreira R, Velz T, Alves N, Gesche V, Malischewski A, Schmitz Rode T, et al. Tissue-engineered heart valve with a tubular leaflet design for minimally invasive transcatheter implantation. Tissue Eng Part C Methods. 2015;21:530-40 pubmed 出版商
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Venalis P, Kumánovics G, Schulze Koops H, Distler A, Dees C, Zerr P, et al. Cardiomyopathy in murine models of systemic sclerosis. Arthritis Rheumatol. 2015;67:508-16 pubmed 出版商
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Lim A, Shin K, Zhao C, Kawano S, Beachy P. Spatially restricted Hedgehog signalling regulates HGF-induced branching of the adult prostate. Nat Cell Biol. 2014;16:1135-45 pubmed 出版商
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Delgado Olguín P, Dang L, He D, Thomas S, Chi L, Sukonnik T, et al. Ezh2-mediated repression of a transcriptional pathway upstream of Mmp9 maintains integrity of the developing vasculature. Development. 2014;141:4610-7 pubmed 出版商
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Kunasegaran K, Ho V, Chang T, De Silva D, Bakker M, Christoffels V, et al. Transcriptional repressor Tbx3 is required for the hormone-sensing cell lineage in mammary epithelium. PLoS ONE. 2014;9:e110191 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 5
  • 免疫印迹; 小鼠; 1:1000; 图 5
Oujo B, Muñoz Félix J, Arévalo M, Núñez Gómez E, Pérez Roque L, Pericacho M, et al. L-Endoglin overexpression increases renal fibrosis after unilateral ureteral obstruction. PLoS ONE. 2014;9:e110365 pubmed 出版商
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Kim W, Barron D, San Martin R, Chan K, Tran L, Yang F, et al. RUNX1 is essential for mesenchymal stem cell proliferation and myofibroblast differentiation. Proc Natl Acad Sci U S A. 2014;111:16389-94 pubmed 出版商
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Cai X, Dai Z, Reeves R, Caballero Benítez A, Duran K, Delrow J, et al. Autonomous stimulation of cancer cell plasticity by the human NKG2D lymphocyte receptor coexpressed with its ligands on cancer cells. PLoS ONE. 2014;9:e108942 pubmed 出版商
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  • 免疫印迹; 小鼠; 图 2
  • 免疫组化-石蜡切片; 人类; 图 2
Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, et al. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex. J Exp Med. 2014;211:2249-63 pubmed 出版商
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Morioka T, Sakabe M, Ioka T, Iguchi T, Mizuta K, Hattammaru M, et al. An important role of endothelial hairy-related transcription factors in mouse vascular development. Genesis. 2014;52:897-906 pubmed 出版商
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Pickup M, Hover L, Polikowsky E, Chytil A, Gorska A, Novitskiy S, et al. BMPR2 loss in fibroblasts promotes mammary carcinoma metastasis via increased inflammation. Mol Oncol. 2015;9:179-91 pubmed 出版商
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Li J, Liu J, Li P, Mao X, Li W, Yang J, et al. Loss of LKB1 disrupts breast epithelial cell polarity and promotes breast cancer metastasis and invasion. J Exp Clin Cancer Res. 2014;33:70 pubmed 出版商
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Miller L, Lincoln J. Isolation of murine valve endothelial cells. J Vis Exp. 2014;: pubmed 出版商
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Vannucchi M, Traini C, Guasti D, Del Popolo G, Faussone Pellegrini M. Telocytes subtypes in human urinary bladder. J Cell Mol Med. 2014;18:2000-8 pubmed 出版商
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Traini C, Faussone Pellegrini M, Evangelista S, Mazzaferro K, Cipriani G, Santicioli P, et al. Inner and outer portions of colonic circular muscle: ultrastructural and immunohistochemical changes in rat chronically treated with otilonium bromide. PLoS ONE. 2014;9:e103237 pubmed 出版商
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Aga M, Bradley J, Wanchu R, Yang Y, Acott T, Keller K. Differential effects of caveolin-1 and -2 knockdown on aqueous outflow and altered extracellular matrix turnover in caveolin-silenced trabecular meshwork cells. Invest Ophthalmol Vis Sci. 2014;55:5497-509 pubmed 出版商
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Calabro S, Maczurek A, Morgan A, Tu T, Wen V, Yee C, et al. Hepatocyte produced matrix metalloproteinases are regulated by CD147 in liver fibrogenesis. PLoS ONE. 2014;9:e90571 pubmed 出版商
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Romero A, Caceres M, Arancibia R, Silva D, Couve E, Martinez C, et al. Cigarette smoke condensate inhibits collagen gel contraction and prostaglandin E2 production in human gingival fibroblasts. J Periodontal Res. 2015;50:371-9 pubmed 出版商
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  • 免疫组化-冰冻切片; pigs
Le Provost G, Pullar C. ?2-adrenoceptor activation modulates skin wound healing processes to reduce scarring. J Invest Dermatol. 2015;135:279-88 pubmed 出版商
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Carlessi L, Fusar Poli E, Bechi G, Mantegazza M, Pascucci B, Narciso L, et al. Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency. Cell Death Dis. 2014;5:e1342 pubmed 出版商
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Owens P, Pickup M, Novitskiy S, Giltnane J, Gorska A, Hopkins C, et al. Inhibition of BMP signaling suppresses metastasis in mammary cancer. Oncogene. 2015;34:2437-49 pubmed 出版商
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Jabari S, da Silveira A, de Oliveira E, Quint K, Wirries A, Neuhuber W, et al. Mucosal layers and related nerve fibres in non-chagasic and chagasic human colon--a quantitative immunohistochemical study. Cell Tissue Res. 2014;358:75-83 pubmed 出版商
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Wagenaar G, Sengers R, Laghmani E, Chen X, Lindeboom M, Roks A, et al. Angiotensin II type 2 receptor ligand PD123319 attenuates hyperoxia-induced lung and heart injury at a low dose in newborn rats. Am J Physiol Lung Cell Mol Physiol. 2014;307:L261-72 pubmed 出版商
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Karow M, Schichor C, Beckervordersandforth R, Berninger B. Lineage-reprogramming of pericyte-derived cells of the adult human brain into induced neurons. J Vis Exp. 2014;: pubmed 出版商
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Gotha L, Lim S, Osherov A, Wolff R, Qiang B, Erlich I, et al. Heparan sulfate side chains have a critical role in the inhibitory effects of perlecan on vascular smooth muscle cell response to arterial injury. Am J Physiol Heart Circ Physiol. 2014;307:H337-45 pubmed 出版商
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Jiang Y, Kou Z, Wu T, An W, Zhou R, Wang H, et al. Xist deficiency and disorders of X-inactivation in rabbit embryonic stem cells can be rescued by transcription-factor-mediated conversion. Stem Cells Dev. 2014;23:2283-96 pubmed 出版商
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Wang J, Eguchi K, Matsumoto S, Fujiu K, Komuro I, Nagai R, et al. The ?-3 polyunsaturated fatty acid, eicosapentaenoic acid, attenuates abdominal aortic aneurysm development via suppression of tissue remodeling. PLoS ONE. 2014;9:e96286 pubmed 出版商
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Zhang J, Hatakeyama J, Eto K, Abe S. Reconstruction of a seminiferous tubule-like structure in a 3 dimensional culture system of re-aggregated mouse neonatal testicular cells within a collagen matrix. Gen Comp Endocrinol. 2014;205:121-32 pubmed 出版商
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Li Y, Pan J, Wei C, Chen J, Liu Y, Liu J, et al. LIM homeodomain transcription factor Isl1 directs normal pyloric development by targeting Gata3. BMC Biol. 2014;12:25 pubmed 出版商
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Moreira R, Gesche V, Hurtado Aguilar L, Schmitz Rode T, Frese J, Jockenhoevel S, et al. TexMi: development of tissue-engineered textile-reinforced mitral valve prosthesis. Tissue Eng Part C Methods. 2014;20:741-8 pubmed 出版商
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Swärd K, Albinsson S, Rippe C. Arterial dysfunction but maintained systemic blood pressure in cavin-1-deficient mice. PLoS ONE. 2014;9:e92428 pubmed 出版商
  • 免疫细胞化学; 人类; 1:250
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Balk Møller E, Kim J, Hopkinson B, Timmermans Wielenga V, Petersen O, Villadsen R. A marker of endocrine receptor-positive cells, CEACAM6, is shared by two major classes of breast cancer: luminal and HER2-enriched. Am J Pathol. 2014;184:1198-208 pubmed 出版商
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Kaenel P, Hahnewald S, Wotzkow C, Strange R, Andres A. Overexpression of EphB4 in the mammary epithelium shifts the differentiation pathway of progenitor cells and promotes branching activity and vascularization. Dev Growth Differ. 2014;56:255-75 pubmed 出版商
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Mäkelä J, Toppari J, Rivero Muller A, Ventelä S. Reconstruction of mouse testicular cellular microenvironments in long-term seminiferous tubule culture. PLoS ONE. 2014;9:e90088 pubmed 出版商
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Namba F, Go H, Murphy J, La P, Yang G, Sengupta S, et al. Expression level and subcellular localization of heme oxygenase-1 modulates its cytoprotective properties in response to lung injury: a mouse model. PLoS ONE. 2014;9:e90936 pubmed 出版商
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Grewal N, Gittenberger de Groot A, Poelmann R, Klautz R, Lindeman J, Goumans M, et al. Ascending aorta dilation in association with bicuspid aortic valve: a maturation defect of the aortic wall. J Thorac Cardiovasc Surg. 2014;148:1583-90 pubmed 出版商
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Son A, Sheleg M, Cooper M, Sun Y, Kleiman N, Zhou R. Formation of persistent hyperplastic primary vitreous in ephrin-A5-/- mice. Invest Ophthalmol Vis Sci. 2014;55:1594-606 pubmed 出版商
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Cuartero S, Fresán U, Reina O, Planet E, Espinàs M. Ibf1 and Ibf2 are novel CP190-interacting proteins required for insulator function. EMBO J. 2014;33:637-47 pubmed 出版商
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Sastre C, Fernández Laso V, Madrigal Matute J, Munoz Garcia B, Moreno J, Pastor Vargas C, et al. Genetic deletion or TWEAK blocking antibody administration reduce atherosclerosis and enhance plaque stability in mice. J Cell Mol Med. 2014;18:721-34 pubmed 出版商
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Yoshida T, Yamashita M, Horimai C, Hayashi M. Deletion of Krüppel-like factor 4 in endothelial and hematopoietic cells enhances neointimal formation following vascular injury. J Am Heart Assoc. 2014;3:e000622 pubmed 出版商
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Redmond E, Liu W, Hamm K, Hatch E, Cahill P, Morrow D. Perivascular delivery of Notch 1 siRNA inhibits injury-induced arterial remodeling. PLoS ONE. 2014;9:e84122 pubmed 出版商
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Chang T, Kunasegaran K, Tarulli G, De Silva D, Voorhoeve P, Pietersen A. New insights into lineage restriction of mammary gland epithelium using parity-identified mammary epithelial cells. Breast Cancer Res. 2014;16:R1 pubmed 出版商
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Toko H, Hariharan N, Konstandin M, Ormachea L, McGregor M, Gude N, et al. Differential regulation of cellular senescence and differentiation by prolyl isomerase Pin1 in cardiac progenitor cells. J Biol Chem. 2014;289:5348-56 pubmed 出版商
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Holzer L, Cor A, Holzer G. Expression of gap junction proteins connexins 26, 30, and 43 in Dupuytren's disease. Acta Orthop. 2014;85:97-101 pubmed 出版商
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  • 免疫组化; 小鼠; 1:400
Nakayama A, Nakayama M, Turner C, Höing S, Lepore J, Adams R. Ephrin-B2 controls PDGFR? internalization and signaling. Genes Dev. 2013;27:2576-89 pubmed 出版商
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Pérot G, Mendiboure J, Brouste V, Velasco V, Terrier P, Bonvalot S, et al. Smooth muscle differentiation identifies two classes of poorly differentiated pleomorphic sarcomas with distinct outcome. Mod Pathol. 2014;27:840-50 pubmed 出版商
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Kerr G, Young J, Horvay K, Abud H, Loveland K. Regulated Wnt/beta-catenin signaling sustains adult spermatogenesis in mice. Biol Reprod. 2014;90:3 pubmed 出版商
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Lafkas D, Rodilla V, Huyghe M, Mourao L, Kiaris H, Fre S. Notch3 marks clonogenic mammary luminal progenitor cells in vivo. J Cell Biol. 2013;203:47-56 pubmed 出版商
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Cagnet S, Faraldo M, Kreft M, Sonnenberg A, Raymond K, Glukhova M. Signaling events mediated by ?3?1 integrin are essential for mammary tumorigenesis. Oncogene. 2014;33:4286-95 pubmed 出版商
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Kossack N, Terwort N, Wistuba J, Ehmcke J, Schlatt S, Scholer H, et al. A combined approach facilitates the reliable detection of human spermatogonia in vitro. Hum Reprod. 2013;28:3012-25 pubmed 出版商
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Burger N, Haak M, de Bakker B, Al Shaibani Z, de Groot C, Christoffels V, et al. Systematic analysis of the development of the ductus venosus in wild type mouse and human embryos. Early Hum Dev. 2013;89:1067-73 pubmed 出版商
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Yang J, Zeini M, Lin C, Lin C, Xiong Y, Shang C, et al. Epicardial calcineurin-NFAT signals through Smad2 to direct coronary smooth muscle cell and arterial wall development. Cardiovasc Res. 2014;101:120-9 pubmed 出版商
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Orecchioni S, Gregato G, Martin Padura I, Reggiani F, Braidotti P, Mancuso P, et al. Complementary populations of human adipose CD34+ progenitor cells promote growth, angiogenesis, and metastasis of breast cancer. Cancer Res. 2013;73:5880-91 pubmed 出版商
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Stewart C, Wang Y, Bonilla Claudio M, Martin J, Gonzalez G, Taketo M, et al. CTNNB1 in mesenchyme regulates epithelial cell differentiation during Müllerian duct and postnatal uterine development. Mol Endocrinol. 2013;27:1442-54 pubmed 出版商
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Martino Echarri E, Fernández Rodríguez R, Rodríguez Baena F, Barrientos Duran A, Torres Collado A, Plaza Calonge M, et al. Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on nidogen-1 and nidogen-2. Int J Cancer. 2013;133:2315-24 pubmed 出版商
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Tripathi P, Wang Y, Coussens M, Manda K, Casey A, Lin C, et al. Activation of NFAT signaling establishes a tumorigenic microenvironment through cell autonomous and non-cell autonomous mechanisms. Oncogene. 2014;33:1840-9 pubmed 出版商
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Ciceri P, Elli F, Brenna I, Volpi E, Brancaccio D, Cozzolino M. The calcimimetic calindol prevents high phosphate-induced vascular calcification by upregulating matrix GLA protein. Nephron Exp Nephrol. 2012;122:75-82 pubmed 出版商
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Jones G, Bown M, Gretarsdottir S, Romaine S, Helgadottir A, Yu G, et al. A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm. Hum Mol Genet. 2013;22:2941-7 pubmed 出版商
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Yu D, Ware C, Waterland R, Zhang J, Chen M, Gadkari M, et al. Developmentally programmed 3' CpG island methylation confers tissue- and cell-type-specific transcriptional activation. Mol Cell Biol. 2013;33:1845-58 pubmed 出版商
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Brereton M, Wareing M, Jones R, Greenwood S. Characterisation of K+ channels in human fetoplacental vascular smooth muscle cells. PLoS ONE. 2013;8:e57451 pubmed 出版商
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Ciceri P, Elli F, Brenna I, Volpi E, Romagnoli S, Tosi D, et al. Lanthanum prevents high phosphate-induced vascular calcification by preserving vascular smooth muscle lineage markers. Calcif Tissue Int. 2013;92:521-30 pubmed 出版商
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Ho W, Davis A, Chadha P, Greenwood I. Effective contractile response to voltage-gated Na+ channels revealed by a channel activator. Am J Physiol Cell Physiol. 2013;304:C739-47 pubmed 出版商
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  • 免疫印迹; 小鼠; 图 5a
Tomasek J, Haaksma C, Schwartz R, Howard E. Whole animal knockout of smooth muscle alpha-actin does not alter excisional wound healing or the fibroblast-to-myofibroblast transition. Wound Repair Regen. 2013;21:166-76 pubmed 出版商
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Steenhard B, Vanacore R, Friedman D, Zelenchuk A, Stroganova L, Isom K, et al. Upregulated expression of integrin ?1 in mesangial cells and integrin ?3 and vimentin in podocytes of Col4a3-null (Alport) mice. PLoS ONE. 2012;7:e50745 pubmed 出版商
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Hoss M, Saric T, Denecke B, Peinkofer G, Bovi M, Groll J, et al. Expansion and differentiation of germline-derived pluripotent stem cells on biomaterials. Tissue Eng Part A. 2013;19:1067-80 pubmed 出版商
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Bouacida A, Rosset P, Trichet V, Guilloton F, Espagnolle N, Cordonier T, et al. Pericyte-like progenitors show high immaturity and engraftment potential as compared with mesenchymal stem cells. PLoS ONE. 2012;7:e48648 pubmed 出版商
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产品信息
Product No. :
A2547
产品名称 :
Monoclonal Anti-Actin, α-Smooth Muscle
宿主 :
小鼠
共轭标签 :
未共轭
抗体类型 :
单克隆
Clone Number (if monoclonal) :
1A4
应用/描述 :
Suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections) using smooth muscle cells; western blot using smooth muscle cells; indirect immunofluorescence: 1:400 using blood vessels in sections of human appendix; immunohistochemistr
物种活性 :
human, frog, sheep, chicken, goat, bovine, rat, guinea pig, mouse, canine, rabbit, snake
抗体亚型 :
IgG2a
储存 :
存放在-20°C
更多信息或购买 :
公司信息
西格玛奥德里奇
上海市徐汇区淮海中路1010号嘉华中心41楼
techservCN@sial.com
http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
公司总部: 美国
Sigma-Aldrich是一家在生命科学领域领先的且拥有高科技产品的公司,致力于为生命科学、制药化工等领域提供高质量的服务和产品。