产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
产品类型 :
抗体
产品名称 :
Monoclonal Anti-Actin, α-Smooth Muscle
目录 :
A2547
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
1A4
反应物种 :
common marmoset, African green monkey, 人类, 小鼠, 大鼠, , , , pigs , fruit fly , 家羊, domestic rabbit, 国内马, 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 其他, 免疫细胞化学基因敲除验证
更多信息或购买 :
文章摘录数: 1642
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:500; 图 4d
Khasawneh R, Kist R, Queen R, Hussain R, Coxhead J, Schneider J, et al. Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype. BMC Dev Biol. 2021;21:14 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3b
  • 免疫组化; 小鼠; 图 1a
  • 免疫印迹; 小鼠; 图 2a
Sun W, Byon C, Kim D, Choi H, Park J, Joo S, et al. Renoprotective Effects of Maslinic Acid on Experimental Renal Fibrosis in Unilateral Ureteral Obstruction Model via Targeting MyD88. Front Pharmacol. 2021;12:708575 pubmed 出版商
  • 免疫印迹; 人类; 图 4b
  • 免疫印迹; 小鼠; 图 2a
Fang L, Wang W, Chen J, Zuo A, Gao H, Yan T, et al. Osthole Attenuates Bleomycin-Induced Pulmonary Fibrosis by Modulating NADPH Oxidase 4-Derived Oxidative Stress in Mice. Oxid Med Cell Longev. 2021;2021:3309944 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 5b
  • 免疫细胞化学; 小鼠; 1:200; 图 1a
  • 免疫印迹; 小鼠; 图 2c, 2j
Xi Y, Li Y, Xu P, Li S, Liu Z, Tung H, et al. The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1. Sci Adv. 2021;7:eabg9241 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 图 4
  • 免疫印迹; 大鼠; 1:1000; 图 5d
Albino A, Zambom F, Foresto Neto O, Oliveira K, Ávila V, Arias S, et al. Renal Inflammation and Innate Immune Activation Underlie the Transition From Gentamicin-Induced Acute Kidney Injury to Renal Fibrosis. Front Physiol. 2021;12:606392 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:1000; 图 1a
  • 免疫细胞化学; 人类; 1:1000; 图 7b
Zehender A, Li Y, Lin N, Stefanica A, Nüchel J, Chen C, et al. TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy. Nat Commun. 2021;12:4404 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 s2b
Zhang D, Huang J, Sun X, Chen H, Huang S, Yang J, et al. Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway. Nat Commun. 2021;12:4391 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 1h
Goyette M, Elkholi I, Apcher C, Kuasne H, Rothlin C, Muller W, et al. Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels. Proc Natl Acad Sci U S A. 2021;118: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:1000; 图 1a
Shani O, Raz Y, Monteran L, Scharff Y, Levi Galibov O, Megides O, et al. Evolution of fibroblasts in the lung metastatic microenvironment is driven by stage-specific transcriptional plasticity. elife. 2021;10: pubmed 出版商
  • 免疫组化; 小鼠; 图 2a
Zhang B, Lapenta K, Wang Q, Nam J, Chung D, Robert M, et al. Trefoil factor 2 secreted from damaged hepatocytes activates hepatic stellate cells to induce fibrogenesis. J Biol Chem. 2021;297:100887 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:4000; 图 5c
  • 免疫组化; 小鼠; 1:1000; 图 s3e
  • 免疫印迹; 人类; 图 5b
Jungwirth U, van Weverwijk A, Evans R, Jenkins L, Vicente D, Alexander J, et al. Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis. Nat Commun. 2021;12:3516 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Ostriker A, Xie Y, Chakraborty R, Sizer A, Bai Y, Ding M, et al. TET2 Protects Against Vascular Smooth Muscle Cell Apoptosis and Intimal Thickening in Transplant Vasculopathy. Circulation. 2021;144:455-470 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:25,000; 图 6b
Barthet V, Brucoli M, Ladds M, Nössing C, Kiourtis C, Baudot A, et al. Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver. Sci Adv. 2021;7: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 图 1d
van Batenburg A, Kazemier K, Van Oosterhout M, van der Vis J, Grutters J, Goldschmeding R, et al. Telomere shortening and DNA damage in culprit cells of different types of progressive fibrosing interstitial lung disease. ERJ Open Res. 2021;7: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 3.1 ug/ml; 图 4b
Williams H, Wadey K, Frankow A, Blythe H, Forbes T, Johnson J, et al. Aneurysm severity is suppressed by deletion of CCN4. J Cell Commun Signal. 2021;15:421-432 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:1000; 图 6c
Palau V, Nugraha B, Benito D, Pascual J, Emmert M, Hoerstrup S, et al. Both Specific Endothelial and Proximal Tubular Adam17 Deletion Protect against Diabetic Nephropathy. Int J Mol Sci. 2021;22: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:1000; 图 6i
  • 免疫细胞化学; 小鼠; 1:1000; 图 2g
Kemp S, Carpenter E, Steele N, Donahue K, Nwosu Z, Pacheco A, et al. Apolipoprotein E Promotes Immune Suppression in Pancreatic Cancer through NF-κB-Mediated Production of CXCL1. Cancer Res. 2021;81:4305-4318 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 6b
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 2a
Flamini S, Sergeev P, Viana de Barros Z, Mello T, Biagioli M, Paglialunga M, et al. Glucocorticoid-induced leucine zipper regulates liver fibrosis by suppressing CCL2-mediated leukocyte recruitment. Cell Death Dis. 2021;12:421 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 1c
Yamamura Y, Furuichi K, Murakawa Y, Hirabayashi S, Yoshihara M, Sako K, et al. Identification of candidate PAX2-regulated genes implicated in human kidney development. Sci Rep. 2021;11:9123 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 1h
O Hare M, Amarnani D, Whitmore H, An M, Marino C, Ramos L, et al. Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators. Am J Pathol. 2021;191:1193-1208 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 5a
  • 免疫印迹; 小鼠; 图 5b
Borges P, Waclawiak I, Georgii J, Fraga Junior V, Barros J, Lemos F, et al. Adenosine Diphosphate Improves Wound Healing in Diabetic Mice Through P2Y12 Receptor Activation. Front Immunol. 2021;12:651740 pubmed 出版商
  • 免疫组化; 人类
Georgopoulou D, Callari M, Rueda O, Shea A, Martin A, Giovannetti A, et al. Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response. Nat Commun. 2021;12:1998 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Fell S, Wang Z, Blanchard A, Nanthakumar C, Griffin M. Transglutaminase 2: a novel therapeutic target for idiopathic pulmonary fibrosis using selective small molecule inhibitors. Amino Acids. 2021;53:205-217 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 1c
Ledein L, Leger B, Dees C, Beyer C, Distler A, Vettori S, et al. Translational engagement of lysophosphatidic acid receptor 1 in skin fibrosis: from dermal fibroblasts of patients with scleroderma to tight skin 1 mouse. Br J Pharmacol. 2020;177:4296-4309 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 1d
Lechertier T, Reynolds L, Kim H, Pedrosa A, Gómez Escudero J, Muñoz Félix J, et al. Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth. Nat Commun. 2020;11:2810 pubmed 出版商
  • 免疫细胞化学; African green monkey; 1:1000; 图 6a
  • 免疫细胞化学; 猕猴; 1:1000; 图 6a
Stauske M, Rodriguez Polo I, Haas W, Knorr D, Borchert T, Streckfuss Bömeke K, et al. Non-Human Primate iPSC Generation, Cultivation, and Cardiac Differentiation under Chemically Defined Conditions. Cells. 2020;9: pubmed 出版商
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Somerville T, Biffi G, Da ler Plenker J, Hur S, He X, Vance K, et al. Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation. elife. 2020;9: pubmed 出版商
  • 免疫组化; 小鼠; 5.0-7.5 ug/ml; 图 2c
Di Gregoli K, Somerville M, Bianco R, Thomas A, Frankow A, Newby A, et al. Galectin-3 Identifies a Subset of Macrophages With a Potential Beneficial Role in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2020;40:1491-1509 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 7
  • 免疫印迹; 小鼠; 1:250; 图 7g, h
Gremlich S, Roth Kleiner M, Equey L, Fytianos K, Schittny J, Cremona T. Tenascin-C inactivation impacts lung structure and function beyond lung development. Sci Rep. 2020;10:5118 pubmed 出版商
  • 免疫组化-石蜡切片; domestic rabbit; 1:500; 图 4a
Meier Bürgisser G, Evrova O, Calcagni M, Scalera C, Giovanoli P, Buschmann J. Impact of PDGF-BB on cellular distribution and extracellular matrix in the healing rabbit Achilles tendon three weeks post-operation. FEBS Open Bio. 2020;10:327-337 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 s8c, s9c
Mantani P, Dunér P, Ljungcrantz I, Nilsson J, Bjorkbacka H, Fredrikson G. ILC2 transfers to apolipoprotein E deficient mice reduce the lipid content of atherosclerotic lesions. BMC Immunol. 2019;20:47 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 4h, s3j, s6f
Yung T, Poon F, Liang M, Coquenlorge S, McGaugh E, Hui C, et al. Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals. Nat Commun. 2019;10:4647 pubmed 出版商
  • 免疫印迹; 人类; 图 5c
Ren J, Smid M, Iaria J, Salvatori D, van Dam H, Zhu H, et al. Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression. Breast Cancer Res. 2019;21:109 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100
Cibi D, Mia M, Guna Shekeran S, Yun L, Sandireddy R, Gupta P, et al. Neural crest-specific deletion of Rbfox2 in mice leads to craniofacial abnormalities including cleft palate. elife. 2019;8: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4f
Wen H, Gao S, Wang Y, Ray M, Magnuson M, Wright C, et al. Myeloid cell-derived HB-EGF Drives Tissue Recovery After Pancreatitis. Cell Mol Gastroenterol Hepatol. 2019;: pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 4c26
An S, Raju I, Surenkhuu B, Kwon J, Gulati S, Karaman M, et al. Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies. Ocul Surf. 2019;: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 6f
Farbehi N, Patrick R, Dorison A, Xaymardan M, Janbandhu V, Wystub Lis K, et al. Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3b
Wu W, Zhang W, Choi M, Zhao J, Gao P, Xue M, et al. Vascular smooth muscle-MAPK14 is required for neointimal hyperplasia by suppressing VSMC differentiation and inducing proliferation and inflammation. Redox Biol. 2019;22:101137 pubmed 出版商
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Sahara M, Santoro F, Sohlmér J, Zhou C, Witman N, Leung C, et al. Population and Single-Cell Analysis of Human Cardiogenesis Reveals Unique LGR5 Ventricular Progenitors in Embryonic Outflow Tract. Dev Cell. 2019;48:475-490.e7 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1i
Wimmer R, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, et al. Human blood vessel organoids as a model of diabetic vasculopathy. Nature. 2019;565:505-510 pubmed 出版商
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Mahmoud M, Evans I, Mehta V, Pellet Many C, Paliashvili K, Zachary I. Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation. Am J Physiol Cell Physiol. 2019;316:C424-C433 pubmed 出版商
  • 免疫组化; 小鼠; 图 s4e
Quitterer U, Fu X, Pohl A, Bayoumy K, Langer A, AbdAlla S. Beta-Arrestin1 Prevents Preeclampsia by Downregulation of Mechanosensitive AT1-B2 Receptor Heteromers. Cell. 2019;176:318-333.e19 pubmed 出版商
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Weltner J, Balboa D, Katayama S, Bespalov M, Krjutskov K, Jouhilahti E, et al. Human pluripotent reprogramming with CRISPR activators. Nat Commun. 2018;9:2643 pubmed 出版商
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García Nores G, Ly C, Cuzzone D, Kataru R, Hespe G, Torrisi J, et al. CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema. Nat Commun. 2018;9:1970 pubmed 出版商
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Rickelt S, Hynes R. Antibodies and methods for immunohistochemistry of extracellular matrix proteins. Matrix Biol. 2018;71-72:10-27 pubmed 出版商
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Ho L, Skiba N, Ullmer C, Rao P. Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2018;59:1969-1984 pubmed 出版商
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  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 2c
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Fu X, Khalil H, Kanisicak O, Boyer J, Vagnozzi R, Maliken B, et al. Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart. J Clin Invest. 2018;128:2127-2143 pubmed 出版商
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Nofi C, Bogatyryov Y, Dedkov E. Preservation of Functional Microvascular Bed Is Vital for Long-Term Survival of Cardiac Myocytes Within Large Transmural Post-Myocardial Infarction Scar. J Histochem Cytochem. 2017;:22155417741640 pubmed 出版商
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Van T, Polykratis A, Straub B, Kondylis V, Papadopoulou N, Pasparakis M. Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. J Clin Invest. 2017;127:2662-2677 pubmed 出版商
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Xia H, Gilbertsen A, Herrera J, Racila E, Smith K, Peterson M, et al. Calcium-binding protein S100A4 confers mesenchymal progenitor cell fibrogenicity in idiopathic pulmonary fibrosis. J Clin Invest. 2017;127:2586-2597 pubmed 出版商
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Tian H, Ketova T, Hardy D, Xu X, Gao X, Zijlstra A, et al. Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading. Arterioscler Thromb Vasc Biol. 2017;37:1115-1126 pubmed 出版商
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Li P, Wang Y, Mao X, Jiang Y, Liu J, Li J, et al. CRB3 downregulation confers breast cancer stem cell traits through TAZ/?-catenin. Oncogenesis. 2017;6:e322 pubmed 出版商
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Qi W, Keenan H, Li Q, Ishikado A, Kannt A, Sadowski T, et al. Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction. Nat Med. 2017;23:753-762 pubmed 出版商
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Gerarduzzi C, Kumar R, Trivedi P, Ajay A, Iyer A, Boswell S, et al. Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation. JCI Insight. 2017;2: pubmed 出版商
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Menicacci B, Laurenzana A, Chillà A, Margheri F, Peppicelli S, Tanganelli E, et al. Chronic Resveratrol Treatment Inhibits MRC5 Fibroblast SASP-Related Protumoral Effects on Melanoma Cells. J Gerontol A Biol Sci Med Sci. 2017;72:1187-1195 pubmed 出版商
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Barry C, Ji E, Sharma H, Beukes L, Vilimas P, Degraaf Y, et al. Morphological and neurochemical differences in peptidergic nerve fibers of the mouse vagina. J Comp Neurol. 2017;525:2394-2410 pubmed 出版商
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Arioka Y, Ito H, Hirata A, Semi K, Yamada Y, Seishima M. Behavior of leucine-rich repeat-containing G-protein coupled receptor 5-expressing cells in the reprogramming process. Stem Cell Res. 2017;20:1-9 pubmed 出版商
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Schatton D, Pla Martín D, Marx M, Hansen H, Mourier A, Nemazanyy I, et al. CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. 2017;216:675-693 pubmed 出版商
  • 免疫组化; 小鼠; 图 2e
Lovric S, Gonçalves S, Gee H, Oskouian B, Srinivas H, Choi W, et al. Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency. J Clin Invest. 2017;127:912-928 pubmed 出版商
  • 免疫组化; 大鼠; 1:100; 图 3a
  • 免疫印迹; 大鼠; 1:2000; 图 2a
Shu D, Wojciechowski M, Lovicu F. Bone Morphogenetic Protein-7 Suppresses TGF?2-Induced Epithelial-Mesenchymal Transition in the Lens: Implications for Cataract Prevention. Invest Ophthalmol Vis Sci. 2017;58:781-796 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2f
Xu J, Zhu S, Heng B, Dissanayaka W, Zhang C. TGF-?1-induced differentiation of SHED into functional smooth muscle cells. Stem Cell Res Ther. 2017;8:10 pubmed 出版商
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Gopal S, Veracini L, Grall D, Butori C, Schaub S, Audebert S, et al. Fibronectin-guided migration of carcinoma collectives. Nat Commun. 2017;8:14105 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 7a
Benito Jardón M, Klapproth S, Gimeno LLuch I, Petzold T, Bharadwaj M, Müller D, et al. The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes. elife. 2017;6: pubmed 出版商
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de Jong R, Paulin N, Lemnitzer P, Viola J, Winter C, Ferraro B, et al. Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report. Arterioscler Thromb Vasc Biol. 2017;37:312-315 pubmed 出版商
  • 免疫细胞化学; 人类; 1:150; 图 s1j
Hosoya M, Fujioka M, Sone T, Okamoto S, Akamatsu W, Ukai H, et al. Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss. Cell Rep. 2017;18:68-81 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 1d
Yang J, Savvatis K, Kang J, Fan P, Zhong H, Schwartz K, et al. Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment. Nat Commun. 2016;7:13710 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:2000; 图 2a
Hofmann K, Fiedler S, Vierkotten S, Weber J, Klee S, Jia J, et al. Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis. Biochim Biophys Acta Mol Basis Dis. 2017;1863:560-568 pubmed 出版商
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Tian S, Li C, Ran R, Chen S. Surfactant protein A deficiency exacerbates renal interstitial fibrosis following obstructive injury in mice. Biochim Biophys Acta Mol Basis Dis. 2017;1863:509-517 pubmed 出版商
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Goreczny G, Ouderkirk Pecone J, Olson E, Krendel M, Turner C. Hic-5 remodeling of the stromal matrix promotes breast tumor progression. Oncogene. 2017;36:2693-2703 pubmed 出版商
  • 免疫细胞化学; 人类; 1:2000; 图 1
Herring A, Messana A, Bara A, Hazelbaker D, Eggan K, Barrett L. Generation of a TLE1 homozygous knockout human embryonic stem cell line using CRISPR-Cas9. Stem Cell Res. 2016;17:430-432 pubmed 出版商
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Grewal N, Franken R, Mulder B, Goumans M, Lindeman J, Jongbloed M, et al. Histopathology of aortic complications in bicuspid aortic valve versus Marfan syndrome: relevance for therapy?. Heart Vessels. 2016;31:795-806 pubmed 出版商
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  • 免疫组化-石蜡切片; 人类; 1:100; 图 8a
Singh N, Kotla S, Dyukova E, Traylor J, Orr A, Chernoff J, et al. Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice. Nat Commun. 2015;6:7450 pubmed 出版商
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Lokody I, Francis J, Gardiner J, Erler J, Swain A. Pten Regulates Epithelial Cytodifferentiation during Prostate Development. PLoS ONE. 2015;10:e0129470 pubmed 出版商
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Ruozi G, Bortolotti F, Falcione A, Dal Ferro M, Ukovich L, Macedo A, et al. AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia. Nat Commun. 2015;6:7388 pubmed 出版商
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Frenay A, Yazdani S, Boersema M, van der Graaf A, Waanders F, van den Born J, et al. Incomplete Restoration of Angiotensin II-Induced Renal Extracellular Matrix Deposition and Inflammation Despite Complete Functional Recovery in Rats. PLoS ONE. 2015;10:e0129732 pubmed 出版商
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Yan M, Chu L, Qin B, Wang Z, Liu X, Jin C, et al. Regulation of NDR1 activity by PLK1 ensures proper spindle orientation in mitosis. Sci Rep. 2015;5:10449 pubmed 出版商
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Wei K, Díaz Trelles R, Liu Q, Diez Cuñado M, Scimia M, Cai W, et al. Developmental origin of age-related coronary artery disease. Cardiovasc Res. 2015;107:287-94 pubmed 出版商
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Pimenta M, Francisco R, Silva R, Porto C, Lazari M. Relaxin affects cell organization and early and late stages of spermatogenesis in a coculture of rat testicular cells. Andrology. 2015;3:772-86 pubmed 出版商
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Louveau A, Smirnov I, Keyes T, Eccles J, Rouhani S, Peske J, et al. Structural and functional features of central nervous system lymphatic vessels. Nature. 2015;523:337-41 pubmed 出版商
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Cushing L, Costinean S, Xu W, Jiang Z, Madden L, Kuang P, et al. Disruption of miR-29 Leads to Aberrant Differentiation of Smooth Muscle Cells Selectively Associated with Distal Lung Vasculature. PLoS Genet. 2015;11:e1005238 pubmed 出版商
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Matsunaga A, Harita Y, Shibagaki Y, Shimizu N, Shibuya K, Ono H, et al. Identification of 4-Trimethylaminobutyraldehyde Dehydrogenase (TMABA-DH) as a Candidate Serum Autoantibody Target for Kawasaki Disease. PLoS ONE. 2015;10:e0128189 pubmed 出版商
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Chevigny M, Guérin Montpetit K, Vargas A, Lefebvre Lavoie J, Lavoie J. Contribution of SRF, Elk-1, and myocardin to airway smooth muscle remodeling in heaves, an asthma-like disease of horses. Am J Physiol Lung Cell Mol Physiol. 2015;309:L37-45 pubmed 出版商
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Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, et al. An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode. J Exp Med. 2015;212:905-25 pubmed 出版商
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Bernichtein S, Pigat N, Capiod T, Boutillon F, Verkarre V, Camparo P, et al. High milk consumption does not affect prostate tumor progression in two mouse models of benign and neoplastic lesions. PLoS ONE. 2015;10:e0125423 pubmed 出版商
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  • 免疫印迹; 人类
Katanov C, Lerrer S, Liubomirski Y, Leider Trejo L, Meshel T, Bar J, et al. Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF-? and the NF-?B pathway. Stem Cell Res Ther. 2015;6:87 pubmed 出版商
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Yongping M, Zhang X, Xuewei L, Fan W, Chen J, Zhang H, et al. Astragaloside prevents BDL-induced liver fibrosis through inhibition of notch signaling activation. J Ethnopharmacol. 2015;169:200-9 pubmed 出版商
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Lee H, Jeong H, Park S, Yoo W, Choi S, Choi K, et al. Fusion protein of retinol-binding protein and albumin domain III reduces liver fibrosis. EMBO Mol Med. 2015;7:819-30 pubmed 出版商
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Li Y, Drabsch Y, Pujuguet P, Ren J, van Laar T, Zhang L, et al. Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models. Breast Cancer Res. 2015;17:28 pubmed 出版商
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Dayer C, Stamenkovic I. Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-β (TGF-β) Activation and Fibroblast Differentiation. J Biol Chem. 2015;290:13763-78 pubmed 出版商
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Maquigussa E, Arnoni C, Pereira L, Boim M. Calcitriol ameliorates renal damage in a pre-established proteinuria model. Mol Med Rep. 2015;12:1009-15 pubmed 出版商
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  • 流式细胞仪; 小鼠; 图 2d
  • 免疫印迹; 小鼠; 图 1c, 5c
Jia D, Duan F, Peng P, Sun L, Ruan Y, Gu J. Pyrroloquinoline-quinone suppresses liver fibrogenesis in mice. PLoS ONE. 2015;10:e0121939 pubmed 出版商
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Videla Richardson G, Garcia C, Roisman A, Slavutsky I, Fernandez Espinosa D, Romorini L, et al. Specific Preferences in Lineage Choice and Phenotypic Plasticity of Glioma Stem Cells Under BMP4 and Noggin Influence. Brain Pathol. 2016;26:43-61 pubmed 出版商
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Yamada A, Aki T, Unuma K, Funakoshi T, Uemura K. Paraquat induces epithelial-mesenchymal transition-like cellular response resulting in fibrogenesis and the prevention of apoptosis in human pulmonary epithelial cells. PLoS ONE. 2015;10:e0120192 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s1
  • 免疫印迹; 人类; 图 s1
Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, et al. Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFα-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. PLoS ONE. 2015;10:e0119415 pubmed 出版商
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Debowski K, Warthemann R, Lentes J, Salinas Riester G, Dressel R, Langenstroth D, et al. Non-viral generation of marmoset monkey iPS cells by a six-factor-in-one-vector approach. PLoS ONE. 2015;10:e0118424 pubmed 出版商
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Kitamura M, Nishino T, Obata Y, Oka S, Abe S, Muta K, et al. The kampo medicine Daikenchuto inhibits peritoneal fibrosis in mice. Biol Pharm Bull. 2015;38:193-200 pubmed 出版商
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Liu M, Flanagan T, Lu C, French A, Argyle D, Corcoran B. Culture and characterisation of canine mitral valve interstitial and endothelial cells. Vet J. 2015;204:32-9 pubmed 出版商
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Kijani S, Yrlid U, Heyden M, Levin M, Borén J, Fogelstrand P. Filter-Dense Multicolor Microscopy. PLoS ONE. 2015;10:e0119499 pubmed 出版商
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Otsuki S, Sawada H, Yodoya N, Shinohara T, Kato T, Ohashi H, et al. Potential contribution of phenotypically modulated smooth muscle cells and related inflammation in the development of experimental obstructive pulmonary vasculopathy in rats. PLoS ONE. 2015;10:e0118655 pubmed 出版商
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Fritz A, Adil M, Mao S, Schaffer D. cAMP and EPAC Signaling Functionally Replace OCT4 During Induced Pluripotent Stem Cell Reprogramming. Mol Ther. 2015;23:952-963 pubmed 出版商
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Gallos G, Yocum G, Siviski M, Yim P, Fu X, Poe M, et al. Selective targeting of the α5-subunit of GABAA receptors relaxes airway smooth muscle and inhibits cellular calcium handling. Am J Physiol Lung Cell Mol Physiol. 2015;308:L931-42 pubmed 出版商
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Afzal M, Strande J. Generation of induced pluripotent stem cells from muscular dystrophy patients: efficient integration-free reprogramming of urine derived cells. J Vis Exp. 2015;:52032 pubmed 出版商
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Yang L, Hu J, Hao H, Yin Z, Liu G, Zou X. Sodium tanshinone IIA sulfonate attenuates the transforming growth factor-β1-induced differentiation of atrial fibroblasts into myofibroblasts in vitro. Int J Mol Med. 2015;35:1026-32 pubmed 出版商
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Shapero K, Wylie Sears J, Levine R, Mayer J, Bischoff J. Reciprocal interactions between mitral valve endothelial and interstitial cells reduce endothelial-to-mesenchymal transition and myofibroblastic activation. J Mol Cell Cardiol. 2015;80:175-85 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1A
  • 免疫印迹; 人类; 图 2A
Bárcena C, Stefanovic M, Tutusaus A, Martinez Nieto G, Martinez L, García Ruiz C, et al. Angiogenin secretion from hepatoma cells activates hepatic stellate cells to amplify a self-sustained cycle promoting liver cancer. Sci Rep. 2015;5:7916 pubmed 出版商
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Malhotra R, Burke M, Martyn T, Shakartzi H, Thayer T, O Rourke C, et al. Inhibition of bone morphogenetic protein signal transduction prevents the medial vascular calcification associated with matrix Gla protein deficiency. PLoS ONE. 2015;10:e0117098 pubmed 出版商
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Coutelle O, Schiffmann L, Liwschitz M, Brunold M, Goede V, Hallek M, et al. Dual targeting of Angiopoetin-2 and VEGF potentiates effective vascular normalisation without inducing empty basement membrane sleeves in xenograft tumours. Br J Cancer. 2015;112:495-503 pubmed 出版商
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Kalwa H, Storch U, Demleitner J, Fiedler S, Mayer T, Kannler M, et al. Phospholipase C epsilon (PLCε) induced TRPC6 activation: a common but redundant mechanism in primary podocytes. J Cell Physiol. 2015;230:1389-99 pubmed 出版商
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Ta M, Rao P, Korgaonkar M, Foster S, Peduto A, Harris D, et al. Pyrrolidine dithiocarbamate reduces the progression of total kidney volume and cyst enlargement in experimental polycystic kidney disease. Physiol Rep. 2014;2: pubmed 出版商
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Vogels R, Vlenterie M, Versleijen Jonkers Y, Ruijter E, Bekers E, Verdijk M, et al. Solitary fibrous tumor - clinicopathologic, immunohistochemical and molecular analysis of 28 cases. Diagn Pathol. 2014;9:224 pubmed 出版商
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O Hara L, McInnes K, Simitsidellis I, Morgan S, Atanassova N, Slowikowska Hilczer J, et al. Autocrine androgen action is essential for Leydig cell maturation and function, and protects against late-onset Leydig cell apoptosis in both mice and men. FASEB J. 2015;29:894-910 pubmed 出版商
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Barnes M, McMullen M, Roychowdhury S, Madhun N, Niese K, Olman M, et al. Macrophage migration inhibitory factor is required for recruitment of scar-associated macrophages during liver fibrosis. J Leukoc Biol. 2015;97:161-9 pubmed 出版商
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Macías D, Fernández Agüera M, Bonilla Henao V, López Barneo J. Deletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia. EMBO Mol Med. 2014;6:1577-92 pubmed 出版商
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Taniguchi T, Asano Y, Akamata K, Noda S, Takahashi T, Ichimura Y, et al. Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated Fli-1-haploinsufficient mice. Arthritis Rheumatol. 2015;67:517-26 pubmed 出版商
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Moreira R, Velz T, Alves N, Gesche V, Malischewski A, Schmitz Rode T, et al. Tissue-engineered heart valve with a tubular leaflet design for minimally invasive transcatheter implantation. Tissue Eng Part C Methods. 2015;21:530-40 pubmed 出版商
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Venalis P, Kumánovics G, Schulze Koops H, Distler A, Dees C, Zerr P, et al. Cardiomyopathy in murine models of systemic sclerosis. Arthritis Rheumatol. 2015;67:508-16 pubmed 出版商
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Lim A, Shin K, Zhao C, Kawano S, Beachy P. Spatially restricted Hedgehog signalling regulates HGF-induced branching of the adult prostate. Nat Cell Biol. 2014;16:1135-45 pubmed 出版商
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Delgado Olguín P, Dang L, He D, Thomas S, Chi L, Sukonnik T, et al. Ezh2-mediated repression of a transcriptional pathway upstream of Mmp9 maintains integrity of the developing vasculature. Development. 2014;141:4610-7 pubmed 出版商
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Kunasegaran K, Ho V, Chang T, De Silva D, Bakker M, Christoffels V, et al. Transcriptional repressor Tbx3 is required for the hormone-sensing cell lineage in mammary epithelium. PLoS ONE. 2014;9:e110191 pubmed 出版商
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Oujo B, Muñoz Félix J, Arévalo M, Núñez Gómez E, Pérez Roque L, Pericacho M, et al. L-Endoglin overexpression increases renal fibrosis after unilateral ureteral obstruction. PLoS ONE. 2014;9:e110365 pubmed 出版商
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Kim W, Barron D, San Martin R, Chan K, Tran L, Yang F, et al. RUNX1 is essential for mesenchymal stem cell proliferation and myofibroblast differentiation. Proc Natl Acad Sci U S A. 2014;111:16389-94 pubmed 出版商
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Cai X, Dai Z, Reeves R, Caballero Benítez A, Duran K, Delrow J, et al. Autonomous stimulation of cancer cell plasticity by the human NKG2D lymphocyte receptor coexpressed with its ligands on cancer cells. PLoS ONE. 2014;9:e108942 pubmed 出版商
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  • 免疫印迹; 小鼠; 图 2
Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, et al. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex. J Exp Med. 2014;211:2249-63 pubmed 出版商
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Morioka T, Sakabe M, Ioka T, Iguchi T, Mizuta K, Hattammaru M, et al. An important role of endothelial hairy-related transcription factors in mouse vascular development. Genesis. 2014;52:897-906 pubmed 出版商
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Pickup M, Hover L, Polikowsky E, Chytil A, Gorska A, Novitskiy S, et al. BMPR2 loss in fibroblasts promotes mammary carcinoma metastasis via increased inflammation. Mol Oncol. 2015;9:179-91 pubmed 出版商
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Li J, Liu J, Li P, Mao X, Li W, Yang J, et al. Loss of LKB1 disrupts breast epithelial cell polarity and promotes breast cancer metastasis and invasion. J Exp Clin Cancer Res. 2014;33:70 pubmed 出版商
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Miller L, Lincoln J. Isolation of murine valve endothelial cells. J Vis Exp. 2014;: pubmed 出版商
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Vannucchi M, Traini C, Guasti D, Del Popolo G, Faussone Pellegrini M. Telocytes subtypes in human urinary bladder. J Cell Mol Med. 2014;18:2000-8 pubmed 出版商
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Traini C, Faussone Pellegrini M, Evangelista S, Mazzaferro K, Cipriani G, Santicioli P, et al. Inner and outer portions of colonic circular muscle: ultrastructural and immunohistochemical changes in rat chronically treated with otilonium bromide. PLoS ONE. 2014;9:e103237 pubmed 出版商
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Aga M, Bradley J, Wanchu R, Yang Y, Acott T, Keller K. Differential effects of caveolin-1 and -2 knockdown on aqueous outflow and altered extracellular matrix turnover in caveolin-silenced trabecular meshwork cells. Invest Ophthalmol Vis Sci. 2014;55:5497-509 pubmed 出版商
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Calabro S, Maczurek A, Morgan A, Tu T, Wen V, Yee C, et al. Hepatocyte produced matrix metalloproteinases are regulated by CD147 in liver fibrogenesis. PLoS ONE. 2014;9:e90571 pubmed 出版商
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Romero A, Caceres M, Arancibia R, Silva D, Couve E, Martinez C, et al. Cigarette smoke condensate inhibits collagen gel contraction and prostaglandin E2 production in human gingival fibroblasts. J Periodontal Res. 2015;50:371-9 pubmed 出版商
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Le Provost G, Pullar C. ?2-adrenoceptor activation modulates skin wound healing processes to reduce scarring. J Invest Dermatol. 2015;135:279-88 pubmed 出版商
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Carlessi L, Fusar Poli E, Bechi G, Mantegazza M, Pascucci B, Narciso L, et al. Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency. Cell Death Dis. 2014;5:e1342 pubmed 出版商
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Owens P, Pickup M, Novitskiy S, Giltnane J, Gorska A, Hopkins C, et al. Inhibition of BMP signaling suppresses metastasis in mammary cancer. Oncogene. 2015;34:2437-49 pubmed 出版商
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Jabari S, da Silveira A, de Oliveira E, Quint K, Wirries A, Neuhuber W, et al. Mucosal layers and related nerve fibres in non-chagasic and chagasic human colon--a quantitative immunohistochemical study. Cell Tissue Res. 2014;358:75-83 pubmed 出版商
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Wagenaar G, Sengers R, Laghmani E, Chen X, Lindeboom M, Roks A, et al. Angiotensin II type 2 receptor ligand PD123319 attenuates hyperoxia-induced lung and heart injury at a low dose in newborn rats. Am J Physiol Lung Cell Mol Physiol. 2014;307:L261-72 pubmed 出版商
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Karow M, Schichor C, Beckervordersandforth R, Berninger B. Lineage-reprogramming of pericyte-derived cells of the adult human brain into induced neurons. J Vis Exp. 2014;: pubmed 出版商
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Gotha L, Lim S, Osherov A, Wolff R, Qiang B, Erlich I, et al. Heparan sulfate side chains have a critical role in the inhibitory effects of perlecan on vascular smooth muscle cell response to arterial injury. Am J Physiol Heart Circ Physiol. 2014;307:H337-45 pubmed 出版商
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Jiang Y, Kou Z, Wu T, An W, Zhou R, Wang H, et al. Xist deficiency and disorders of X-inactivation in rabbit embryonic stem cells can be rescued by transcription-factor-mediated conversion. Stem Cells Dev. 2014;23:2283-96 pubmed 出版商
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Wang J, Eguchi K, Matsumoto S, Fujiu K, Komuro I, Nagai R, et al. The ?-3 polyunsaturated fatty acid, eicosapentaenoic acid, attenuates abdominal aortic aneurysm development via suppression of tissue remodeling. PLoS ONE. 2014;9:e96286 pubmed 出版商
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Zhang J, Hatakeyama J, Eto K, Abe S. Reconstruction of a seminiferous tubule-like structure in a 3 dimensional culture system of re-aggregated mouse neonatal testicular cells within a collagen matrix. Gen Comp Endocrinol. 2014;205:121-32 pubmed 出版商
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Li Y, Pan J, Wei C, Chen J, Liu Y, Liu J, et al. LIM homeodomain transcription factor Isl1 directs normal pyloric development by targeting Gata3. BMC Biol. 2014;12:25 pubmed 出版商
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Moreira R, Gesche V, Hurtado Aguilar L, Schmitz Rode T, Frese J, Jockenhoevel S, et al. TexMi: development of tissue-engineered textile-reinforced mitral valve prosthesis. Tissue Eng Part C Methods. 2014;20:741-8 pubmed 出版商
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Swärd K, Albinsson S, Rippe C. Arterial dysfunction but maintained systemic blood pressure in cavin-1-deficient mice. PLoS ONE. 2014;9:e92428 pubmed 出版商
  • 免疫细胞化学; 人类; 1:250
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Balk Møller E, Kim J, Hopkinson B, Timmermans Wielenga V, Petersen O, Villadsen R. A marker of endocrine receptor-positive cells, CEACAM6, is shared by two major classes of breast cancer: luminal and HER2-enriched. Am J Pathol. 2014;184:1198-208 pubmed 出版商
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Kaenel P, Hahnewald S, Wotzkow C, Strange R, Andres A. Overexpression of EphB4 in the mammary epithelium shifts the differentiation pathway of progenitor cells and promotes branching activity and vascularization. Dev Growth Differ. 2014;56:255-75 pubmed 出版商
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Mäkelä J, Toppari J, Rivero Muller A, Ventelä S. Reconstruction of mouse testicular cellular microenvironments in long-term seminiferous tubule culture. PLoS ONE. 2014;9:e90088 pubmed 出版商
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产品信息
Product No. :
A2547
产品名称 :
Monoclonal Anti-Actin, α-Smooth Muscle
宿主 :
小鼠
共轭标签 :
未共轭
抗体类型 :
单克隆
Clone Number (if monoclonal) :
1A4
应用/描述 :
Suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections) using smooth muscle cells; western blot using smooth muscle cells; indirect immunofluorescence: 1:400 using blood vessels in sections of human appendix; immunohistochemistr
物种活性 :
human, frog, sheep, chicken, goat, bovine, rat, guinea pig, mouse, canine, rabbit, snake
抗体亚型 :
IgG2a
储存 :
存放在-20°C
更多信息或购买 :
公司信息
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http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
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