公司名称 :
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
产品类型 :
产品名称 :
Monoclonal Anti-β-Actin antibody produced in mouse
目录 :
克隆性 :
宿主 :
共轭标签 :
克隆名称 :
反应物种 :
African green monkey, 仓鼠, zebra finch, Burton's mouthbrooder, Garra rufa, 人类, 小鼠, 大鼠, , , , pigs , 斑马鱼, fruit fly , 家羊, domestic rabbit
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, 其他, 免疫印迹基因敲除验证, 免疫组化基因敲除验证, 免疫细胞化学基因敲除验证
更多信息或购买 :
文章摘录数: 6505
  • 免疫印迹; African green monkey; 1:10,000; 图 4c
  • 免疫印迹; 大鼠; 图 4c
Watanabe D, Nakagawa S, Morofuji Y, Tóth A, Vastag M, Aruga J, et al. Characterization of a Primate Blood-Brain Barrier Co-Culture Model Prepared from Primary Brain Endothelial Cells, Pericytes and Astrocytes. Pharmaceutics. 2021;13: pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 1e
Ma S, Mangala L, Hu W, Bayaktar E, Yokoi A, Hu W, et al. CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance. Cell Rep. 2021;36:109549 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 4a
Ito S, Nomura T, Ueda T, Inui S, Morioka Y, Honjo H, et al. Gene expression profiles during tissue remodeling following bladder outlet obstruction. Sci Rep. 2021;11:13171 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Wang J, Zhang Y, Xiao Y, Yuan X, Li P, Wang X, et al. Boosting immune surveillance by low-dose PI3K inhibitor facilitates early intervention of breast cancer. Am J Cancer Res. 2021;11:2005-2024 pubmed
  • 免疫印迹; 人类; 图 3a
Koeniger A, Brichkina A, Nee I, Dempwolff L, Hupfer A, Galperin I, et al. Activation of Cilia-Independent Hedgehog/GLI1 Signaling as a Novel Concept for Neuroblastoma Therapy. Cancers (Basel). 2021;13: pubmed 出版商
  • 免疫印迹; 人类; 图 s9c
Fang W, Sofia Acevedo D, Smart C, Zinda B, Alissa N, Warren K, et al. Expression of CCL2/CCR2 signaling proteins in breast carcinoma cells is associated with invasive progression. Sci Rep. 2021;11:8708 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1h
Sharma V, Sood R, Lou D, Hung T, Levesque M, Han Y, et al. 4E-BP2-dependent translation in parvalbumin neurons controls epileptic seizure threshold. Proc Natl Acad Sci U S A. 2021;118: pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1d
Baquero J, Benitez Buelga C, Rajagopal V, Zhenjun Z, Torres Ruiz R, Muller S, et al. Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects. Sci Rep. 2021;11:3490 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 1a
Iwata S, Morikawa M, Takei Y, Hirokawa N. An activity-dependent local transport regulation via degradation and synthesis of KIF17 underlying cognitive flexibility. Sci Adv. 2020;6: pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 s5a
Torretta S, Scagliola A, Ricci L, Mainini F, Di Marco S, Cuccovillo I, et al. D-mannose suppresses macrophage IL-1β production. Nat Commun. 2020;11:6343 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 4b
Pavlova N, King B, Josselsohn R, Violante S, Macera V, Vardhana S, et al. Translation in amino-acid-poor environments is limited by tRNAGln charging. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 s3-1a
Riou R, Ladli M, Gerbal Chaloin S, Bossard P, Gougelet A, Godard C, et al. ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 9a
Boucher J, Balandre A, Debant M, Vix J, Harnois T, Bourmeyster N, et al. Cx43 Present at the Leading Edge Membrane Governs Promigratory Effects of Osteoblast-Conditioned Medium on Human Prostate Cancer Cells in the Context of Bone Metastasis. Cancers (Basel). 2020;12: pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Huang Y, Liang C, Ritz D, Coelho R, Septiadi D, Estermann M, et al. Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 1:4000; 图 3c
Blazquez C, Ruiz Calvo A, Bajo Grañeras R, Baufreton J, Resel E, Varilh M, et al. Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1d
Huang H, Liu R, Huang Y, Feng Y, Fu Y, Chen L, et al. Acetylation-mediated degradation of HSD17B4 regulates the progression of prostate cancer. Aging (Albany NY). 2020;12:14699-14717 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s6k
Yamamoto K, Venida A, Yano J, Biancur D, Kakiuchi M, Gupta S, et al. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020;581:100-105 pubmed 出版商
  • 免疫印迹; 斑马鱼; 图 s1e
Golenberg N, Squirrell J, Bennin D, Rindy J, Pistono P, Eliceiri K, et al. Citrullination regulates wound responses and tissue regeneration in zebrafish. J Cell Biol. 2020;219: pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 4d
Zhang R, Liakath Ali K, Sudhof T. Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4b
De Luna N, Turon Sans J, Cortés Vicente E, Carrasco Rozas A, Illán Gala I, Dols Icardo O, et al. Downregulation of miR-335-5P in Amyotrophic Lateral Sclerosis Can Contribute to Neuronal Mitochondrial Dysfunction and Apoptosis. Sci Rep. 2020;10:4308 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 1:1000; 图 5a
Bajpai R, Sharma A, Achreja A, Edgar C, Wei C, Siddiqa A, et al. Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma. Nat Commun. 2020;11:1228 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000; 图 1-1, 1-2,
Shibahara T, Ago T, Nakamura K, Tachibana M, Yoshikawa Y, Komori M, et al. Pericyte-Mediated Tissue Repair through PDGFRβ Promotes Peri-Infarct Astrogliosis, Oligodendrogenesis, and Functional Recovery after Acute Ischemic Stroke. Eneuro. 2020;7: pubmed 出版商
  • 免疫印迹; 小鼠; 图 4d
Yang F, Huang X, Zang R, Chen J, Fidalgo M, Sanchez Priego C, et al. DUX-miR-344-ZMYM2-Mediated Activation of MERVL LTRs Induces a Totipotent 2C-like State. Cell Stem Cell. 2020;26:234-250.e7 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 2d
Majewski L, Maciąg F, Boguszewski P, Kuznicki J. Transgenic Mice Overexpressing Human STIM2 and ORAI1 in Neurons Exhibit Changes in Behavior and Calcium Homeostasis but Show No Signs of Neurodegeneration. Int J Mol Sci. 2020;21: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7h
Chen F, Liu X, Chen Y, Liu J, Lu H, Wang W, et al. Sphere-induced reprogramming of RPE cells into dual-potential RPE stem-like cells. EBioMedicine. 2020;52:102618 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 5a
Hsu H, Liu C, Lin J, Hsu T, Hsu J, Li A, et al. Involvement of collagen XVII in pluripotency gene expression and metabolic reprogramming of lung cancer stem cells. J Biomed Sci. 2020;27:5 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 4f
Hiepen C, Jatzlau J, Hildebrandt S, Kampfrath B, Goktas M, Murgai A, et al. BMPR2 acts as a gatekeeper to protect endothelial cells from increased TGFβ responses and altered cell mechanics. PLoS Biol. 2019;17:e3000557 pubmed 出版商
  • 免疫印迹; African green monkey; 1:10,000; 图 3a
Lehmann M, Lukonin I, Noe F, Schmoranzer J, Clementi C, Loerke D, et al. Nanoscale coupling of endocytic pit growth and stability. Sci Adv. 2019;5:eaax5775 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 5c
Zhang Y, Thery F, Wu N, Luhmann E, Dussurget O, Foecke M, et al. The in vivo ISGylome links ISG15 to metabolic pathways and autophagy upon Listeria monocytogenes infection. Nat Commun. 2019;10:5383 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b
Padmanaban V, Krol I, Suhail Y, Szczerba B, Aceto N, Bader J, et al. E-cadherin is required for metastasis in multiple models of breast cancer. Nature. 2019;573:439-444 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s1h
Sanghvi V, Leibold J, Mina M, Mohan P, Berishaj M, Li Z, et al. The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase. Cell. 2019;178:807-819.e21 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Yang M, Chen P, Liu J, Zhu S, Kroemer G, Klionsky D, et al. Clockophagy is a novel selective autophagy process favoring ferroptosis. Sci Adv. 2019;5:eaaw2238 pubmed 出版商
  • 免疫印迹; 人类; 图 s7
Ortega F, Roefs M, De Miguel Pérez D, Kooijmans S, de Jong O, Sluijter J, et al. Interfering with endolysosomal trafficking enhances release of bioactive exosomes. Nanomedicine. 2019;:102014 pubmed 出版商
  • 免疫细胞化学; 人类; 1:10,000; 图 2s1b
Bayer S, Grither W, Brenot A, Hwang P, Barcus C, Ernst M, et al. DDR2 controls breast tumor stiffness and metastasis by regulating integrin mediated mechanotransduction in CAFs. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1a
Mikuličić S, Finke J, Boukhallouk F, Wüstenhagen E, Sons D, Homsi Y, et al. ADAM17-dependent signaling is required for oncogenic human papillomavirus entry platform assembly. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Kong X, Chen J, Xie W, Brown S, Cai Y, Wu K, et al. Defining UHRF1 Domains that Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties. Cancer Cell. 2019;35:633-648.e7 pubmed 出版商
  • 免疫印迹; 人类; 图 1d
Zhang X, Wang L, Ireland S, Ahat E, Li J, Bekier Ii M, et al. GORASP2/GRASP55 collaborates with the PtdIns3K UVRAG complex to facilitate autophagosome-lysosome fusion. Autophagy. 2019;:1-14 pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 3b
Wobser M, Weber A, Glunz A, Tauch S, Seitz K, Butelmann T, et al. Elucidating the mechanism of action of domatinostat (4SC-202) in cutaneous T cell lymphoma cells. J Hematol Oncol. 2019;12:30 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 2b
Diamond E, Durham B, Ulaner G, Drill E, Buthorn J, Ki M, et al. Efficacy of MEK inhibition in patients with histiocytic neoplasms. Nature. 2019;567:521-524 pubmed 出版商
  • 免疫印迹; 大鼠; 图 s1
Hlavac N, VandeVord P. Astrocyte Mechano-Activation by High-Rate Overpressure Involves Alterations in Structural and Junctional Proteins. Front Neurol. 2019;10:99 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 8a
Carballo Carbajal I, Laguna A, Romero Gimenez J, Cuadros T, Bove J, Martinez Vicente M, et al. Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis. Nat Commun. 2019;10:973 pubmed 出版商
  • 免疫印迹; 小鼠; 1:30,000; 图 4a
Zhu H, Bhatt B, Sivaprakasam S, Cai Y, Liu S, Kodeboyina S, et al. Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR. Nat Commun. 2019;10:1084 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Horos R, Büscher M, Kleinendorst R, Alleaume A, Tarafder A, Schwarzl T, et al. The Small Non-coding Vault RNA1-1 Acts as a Riboregulator of Autophagy. Cell. 2019;176:1054-1067.e12 pubmed 出版商
  • 免疫印迹; 仓鼠; 1:5000; 图 8a
Vrijens P, Noppen S, Boogaerts T, Vanstreels E, Ronca R, Chiodelli P, et al. Influenza virus entry via the GM3 ganglioside-mediated platelet-derived growth factor receptor β signalling pathway. J Gen Virol. 2019;100:583-601 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4d
Frank T, Tuppi M, Hugle M, Dötsch V, van Wijk S, Fulda S. Cell cycle arrest in mitosis promotes interferon-induced necroptosis. Cell Death Differ. 2019;: pubmed 出版商
  • 免疫印迹; 小鼠; 图 s7a
Gronke K, Hernandez P, Zimmermann J, Klose C, Kofoed Branzk M, Guendel F, et al. Interleukin-22 protects intestinal stem cells against genotoxic stress. Nature. 2019;566:249-253 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1d
Beug S, Cheung H, Sanda T, St Jean M, Beauregard C, Mamady H, et al. The transcription factor SP3 drives TNF-α expression in response to Smac mimetics. Sci Signal. 2019;12: pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 4a
Oliveira H, Roma Rodrigues C, Santos A, Veigas B, Brás N, Faria A, et al. GLUT1 and GLUT3 involvement in anthocyanin gastric transport- Nanobased targeted approach. Sci Rep. 2019;9:789 pubmed 出版商
  • 免疫印迹; 人类; 图 2e
Sayas C, Medina M, Cuadros R, Ollá I, Garcia E, Perez M, et al. Role of tau N-terminal motif in the secretion of human tau by End Binding proteins. PLoS ONE. 2019;14:e0210864 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 5a
Poulopoulos A, Murphy A, Ozkan A, Davis P, Hatch J, Kirchner R, et al. Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. Nature. 2019;565:356-360 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Martins R, Malbert Colas L, Lista M, Daskalogianni C, Apcher S, Pla M, et al. Nuclear processing of nascent transcripts determines synthesis of full-length proteins and antigenic peptides. Nucleic Acids Res. 2019;47:3086-3100 pubmed 出版商
  • 免疫印迹; 人类; 图 4c
Urtishak K, Wang L, Culjkovic Kraljacic B, Davenport J, Porazzi P, Vincent T, et al. Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia. Oncogene. 2019;38:2241-2262 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3a
Rai S, Arasteh M, Jefferson M, Pearson T, Wang Y, Zhang W, et al. The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis. Autophagy. 2019;15:599-612 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Xu P, Chen A, Ganaie S, Cheng F, Shen W, Wang X, et al. The 11-Kilodalton Nonstructural Protein of Human Parvovirus B19 Facilitates Viral DNA Replication by Interacting with Grb2 through Its Proline-Rich Motifs. J Virol. 2019;93: pubmed 出版商
  • 免疫印迹; 人类; 1:20,000; 图 s10d
Ruscetti M, Leibold J, Bott M, Fennell M, Kulick A, Salgado N, et al. NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination. Science. 2018;362:1416-1422 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4m
Wang M, Tang C, Xing R, Liu X, Han X, Liu Y, et al. WDR81 regulates adult hippocampal neurogenesis through endosomal SARA-TGFβ signaling. Mol Psychiatry. 2018;: pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1c
Sarracino A, Gharu L, Kula A, Pasternak A, Avettand Fenoel V, Rouzioux C, et al. Posttranscriptional Regulation of HIV-1 Gene Expression during Replication and Reactivation from Latency by Nuclear Matrix Protein MATR3. MBio. 2018;9: pubmed 出版商
  • 免疫印迹; 人类; 1:6000; 图 4b
Persi E, Duran Frigola M, Damaghi M, Roush W, Aloy P, Cleveland J, et al. Systems analysis of intracellular pH vulnerabilities for cancer therapy. Nat Commun. 2018;9:2997 pubmed 出版商
  • 免疫印迹; 人类; 图 s4c
Liu H, Lorenzini P, Zhang F, Xu S, Wong M, Zheng J, et al. Alternative splicing analysis in human monocytes and macrophages reveals MBNL1 as major regulator. Nucleic Acids Res. 2018;46:6069-6086 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5f
Fujimoto M, Takii R, Katiyar A, Srivastava P, Nakai A. Poly(ADP-Ribose) Polymerase 1 Promotes the Human Heat Shock Response by Facilitating Heat Shock Transcription Factor 1 Binding to DNA. Mol Cell Biol. 2018;38: pubmed 出版商
  • 免疫印迹; 人类; 图 8a
Soncin F, Khater M, To C, Pizzo D, Farah O, Wakeland A, et al. Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development. Development. 2018;145: pubmed 出版商
  • 免疫印迹; 小鼠; 图 s1c
Teater M, Domínguez P, Redmond D, Chen Z, Ennishi D, Scott D, et al. AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis. Nat Commun. 2018;9:222 pubmed 出版商
  • 免疫印迹; 小鼠; 1:20,000; 图 1a
Sala M, Chen C, Zhang Q, Do Umehara H, Wu W, Misharin A, et al. JNK2 up-regulates hypoxia-inducible factors and contributes to hypoxia-induced erythropoiesis and pulmonary hypertension. J Biol Chem. 2018;293:271-284 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s6a
Kumar S, Nakashizuka H, Jones A, Lambert A, Zhao X, Shen M, et al. Proteolytic Degradation and Inflammation Play Critical Roles in Polypoidal Choroidal Vasculopathy. Am J Pathol. 2017;187:2841-2857 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 3c
Simond A, Rao T, Zuo D, Zhao J, Muller W. ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor. Oncogene. 2017;36:6059-6066 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2f
Read M, Fong J, Modasia B, Fletcher A, Imruetaicharoenchoke W, Thompson R, et al. Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer. Oncogene. 2017;36:5296-5308 pubmed 出版商
  • 免疫印迹; 大鼠; 图 1d
Rippe C, Zhu B, Krawczyk K, Bavel E, Albinsson S, Sjölund J, et al. Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway. Sci Rep. 2017;7:1334 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 5a
Cho H, Kim J, Jang H, Lee T, Jung M, Kim T, et al. Alpha-lipoic acid ameliorates the epithelial mesenchymal transition induced by unilateral ureteral obstruction in mice. Sci Rep. 2017;7:46065 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1C
Busnelli M, Manzini S, Hilvo M, Parolini C, Ganzetti G, Dellera F, et al. Liver-specific deletion of the Plpp3 gene alters plasma lipid composition and worsens atherosclerosis in apoE-/- mice. Sci Rep. 2017;7:44503 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 6a
Pi H, Li M, Tian L, Yang Z, Yu Z, Zhou Z. Enhancing lysosomal biogenesis and autophagic flux by activating the transcription factor EB protects against cadmium-induced neurotoxicity. Sci Rep. 2017;7:43466 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Sun A, Wei J, Childress C, Shaw J, Peng K, Shao G, et al. The E3 ubiquitin ligase NEDD4 is an LC3-interactive protein and regulates autophagy. Autophagy. 2017;13:522-537 pubmed 出版商
  • 免疫细胞化学基因敲除验证; 小鼠; 图 1b
  • 免疫印迹基因敲除验证; 小鼠; 图 1i
Patrinostro X, O Rourke A, Chamberlain C, Moriarity B, Perrin B, Ervasti J. Relative importance of ?cyto- and ?cyto-actin in primary mouse embryonic fibroblasts. Mol Biol Cell. 2017;28:771-782 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Natarajan S, Muthukrishnan E, Khalimonchuk O, Mott J, Becker D. Evidence for Pipecolate Oxidase in Mediating Protection Against Hydrogen Peroxide Stress. J Cell Biochem. 2017;118:1678-1688 pubmed 出版商
  • 免疫印迹; 小鼠; 图 8
Wizeman J, Nicholas A, Ishigami A, Mohan R. Citrullination of glial intermediate filaments is an early response in retinal injury. Mol Vis. 2016;22:1137-1155 pubmed
  • 免疫印迹; 小鼠; 图 2
  • 免疫印迹; 人类; 图 2
Cizmecioglu O, Ni J, Xie S, Zhao J, Roberts T. Rac1-mediated membrane raft localization of PI3K/p110? is required for its activation by GPCRs or PTEN loss. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 大鼠; 图 5
  • 免疫印迹; 人类; 图 1
Hesler R, Huang J, Starr M, Treboschi V, Bernanke A, Nixon A, et al. TGF-?-induced stromal CYR61 promotes resistance to gemcitabine in pancreatic ductal adenocarcinoma through downregulation of the nucleoside transporters hENT1 and hCNT3. Carcinogenesis. 2016;37:1041-1051 pubmed 出版商
  • 免疫印迹; 人类; 图 3
García Carpizo V, Sarmentero J, Han B, Grana O, Ruiz Llorente S, Pisano D, et al. NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation. Sci Rep. 2016;6:32952 pubmed 出版商
  • 免疫印迹; 大鼠; 图 2
Kim J, Kim C, Sohn E, Kim J. Cytoplasmic translocation of high-mobility group box-1 protein is induced by diabetes and high glucose in retinal pericytes. Mol Med Rep. 2016;14:3655-61 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 4
Lee M, Tsai K, Hsu J, Shin S, Wu J, Yeh J. Liraglutide prevents and reverses monocrotaline-induced pulmonary arterial hypertension by suppressing ET-1 and enhancing eNOS/sGC/PKG pathways. Sci Rep. 2016;6:31788 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3a
Krawczyk K, Ekman M, Rippe C, Grossi M, Nilsson B, Albinsson S, et al. Assessing the contribution of thrombospondin-4 induction and ATF6? activation to endoplasmic reticulum expansion and phenotypic modulation in bladder outlet obstruction. Sci Rep. 2016;6:32449 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Yamada H, Takeda T, Michiue H, Abe T, Takei K. Actin bundling by dynamin 2 and cortactin is implicated in cell migration by stabilizing filopodia in human non-small cell lung carcinoma cells. Int J Oncol. 2016;49:877-86 pubmed 出版商
  • 免疫印迹; 人类; 图 s3
Wilkie A, Lawler J, Coen D. A Role for Nuclear F-Actin Induction in Human Cytomegalovirus Nuclear Egress. MBio. 2016;7: pubmed 出版商
  • 免疫印迹; 人类; 图 3
Sakai Y, Miyake A, Doi N, Sasada H, Miyazaki Y, Adachi A, et al. Expression Profiles of Vpx/Vpr Proteins Are Co-related with the Primate Lentiviral Lineage. Front Microbiol. 2016;7:1211 pubmed 出版商
  • 免疫印迹; 人类; 图 s6
Gusscott S, Jenkins C, Lam S, Giambra V, Pollak M, Weng A. IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias. PLoS ONE. 2016;11:e0161158 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 4c
  • 免疫印迹; 小鼠; 1:5000; 图 1a
Sun L, Fan G, Shan P, Qiu X, Dong S, Liao L, et al. Regulation of energy homeostasis by the ubiquitin-independent REG? proteasome. Nat Commun. 2016;7:12497 pubmed 出版商
  • 免疫印迹; 小鼠; 图 8
Meliopoulos V, Van De Velde L, Van De Velde N, Karlsson E, Neale G, Vogel P, et al. An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens. PLoS Pathog. 2016;12:e1005804 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Wong M, Chen S. Human Choline Kinase-? Promotes Hepatitis C Virus RNA Replication through Modulation of Membranous Viral Replication Complex Formation. J Virol. 2016;90:9075-95 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3A
  • 免疫印迹; 人类; 图 4A
Zhang M, Qi Y, Li H, Cui J, Dai L, Frank J, et al. AIM2 inflammasome mediates Arsenic-induced secretion of IL-1 ? and IL-18. Oncoimmunology. 2016;5:e1160182 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Cabral W, Ishikawa M, Garten M, Makareeva E, Sargent B, Weis M, et al. Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta. PLoS Genet. 2016;12:e1006156 pubmed 出版商
  • 免疫印迹; fruit fly ; 图 s1
Penney J, Tsurudome K, Liao E, Kauwe G, Gray L, Yanagiya A, et al. LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction. Nat Commun. 2016;7:12188 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Li S, Qu Z, Haas M, Ngo L, Heo Y, Kang H, et al. The HSA21 gene EURL/C21ORF91 controls neurogenesis within the cerebral cortex and is implicated in the pathogenesis of Down Syndrome. Sci Rep. 2016;6:29514 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Kawano S, Grassian A, Tsuda M, Knutson S, Warholic N, Kuznetsov G, et al. Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma. PLoS ONE. 2016;11:e0158888 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000; 图 s7
Wang M, Sips P, Khin E, Rotival M, Sun X, Ahmed R, et al. Wars2 is a determinant of angiogenesis. Nat Commun. 2016;7:12061 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 3
Bayne R, Donnachie D, Kinnell H, Childs A, Anderson R. BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2. Mol Hum Reprod. 2016;22:622-33 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Davis M, Delaney J, Patel C, Storgard R, Stupack D. Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings. Drug Des Devel Ther. 2016;10:1837-46 pubmed 出版商
  • 免疫印迹; 小鼠; 1:15,000; 图 s3
Herring A, Münster Y, Akkaya T, Moghaddam S, Deinsberger K, Meyer J, et al. Kallikrein-8 inhibition attenuates Alzheimer's disease pathology in mice. Alzheimers Dement. 2016;12:1273-1287 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Helmke C, Raab M, Rodel F, Matthess Y, Oellerich T, Mandal R, et al. Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8. Cell Res. 2016;26:914-34 pubmed 出版商
  • 免疫印迹; 大鼠; 1:10,000; 图 6
Kovacevic S, Nestorov J, Matić G, Elaković I. Fructose and stress induce opposite effects on lipid metabolism in the visceral adipose tissue of adult female rats through glucocorticoid action. Eur J Nutr. 2017;56:2115-2128 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 3
Kathania M, Khare P, Zeng M, Cantarel B, Zhang H, Ueno H, et al. Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-?t ubiquitination. Nat Immunol. 2016;17:997-1004 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 表 2
Muñoz Félix J, Pérez Roque L, Núñez Gómez E, Oujo B, Arevalo M, Ruiz Remolina L, et al. Overexpression of the short endoglin isoform reduces renal fibrosis and inflammation after unilateral ureteral obstruction. Biochim Biophys Acta. 2016;1862:1801-14 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 6
Mohammed H, Pickard M, Mourtada Maarabouni M. The protein phosphatase 4 - PEA15 axis regulates the survival of breast cancer cells. Cell Signal. 2016;28:1389-400 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1
Toneff M, Sreekumar A, Tinnirello A, Hollander P, Habib S, Li S, et al. The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states. BMC Biol. 2016;14:47 pubmed 出版商
  • 免疫印迹; 小鼠; 1:15,000; 图 7
Herring A, Münster Y, Metzdorf J, Bolczek B, Krüssel S, Krieter D, et al. Late running is not too late against Alzheimer's pathology. Neurobiol Dis. 2016;94:44-54 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Kanemori Y, Koga Y, Sudo M, Kang W, Kashiwabara S, Ikawa M, et al. Biogenesis of sperm acrosome is regulated by pre-mRNA alternative splicing of Acrbp in the mouse. Proc Natl Acad Sci U S A. 2016;113:E3696-705 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7
Muroyama A, Seldin L, Lechler T. Divergent regulation of functionally distinct γ-tubulin complexes during differentiation. J Cell Biol. 2016;213:679-92 pubmed 出版商
  • 免疫印迹; 小鼠
Kim H, Lee J, Park K, Kim W, Roh G. A mitochondrial division inhibitor, Mdivi-1, inhibits mitochondrial fragmentation and attenuates kainic acid-induced hippocampal cell death. BMC Neurosci. 2016;17:33 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Kobayashi K, Araya J, Minagawa S, Hara H, Saito N, Kadota T, et al. Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis. J Immunol. 2016;197:504-16 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Andersen A, Flinck M, Oernbo E, Pedersen N, Viuff B, Pedersen S. Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment. Mol Cancer. 2016;15:45 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Wang X, Mazurkiewicz M, Hillert E, Olofsson M, Pierrou S, Hillertz P, et al. The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells. Sci Rep. 2016;6:26979 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Ando K, Tomimura K, Sazdovitch V, Suain V, Yilmaz Z, Authelet M, et al. Level of PICALM, a key component of clathrin-mediated endocytosis, is correlated with levels of phosphotau and autophagy-related proteins and is associated with tau inclusions in AD, PSP and Pick disease. Neurobiol Dis. 2016;94:32-43 pubmed 出版商
  • 免疫印迹; 大鼠; 1:10,000; 图 1
Garcia Fuster M, Garcia Sevilla J. Effects of anti-depressant treatments on FADD and p-FADD protein in rat brain cortex: enhanced anti-apoptotic p-FADD/FADD ratio after chronic desipramine and fluoxetine administration. Psychopharmacology (Berl). 2016;233:2955-71 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Krachulec J, Sedlmeier G, Thiele W, Sleeman J. Footprintless disruption of prosurvival genes in aneuploid cancer cells using CRISPR/Cas9 technology. Biochem Cell Biol. 2016;94:289-96 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Tzani I, Ivanov I, Andreev D, Dmitriev R, Dean K, Baranov P, et al. Systematic analysis of the PTEN 5' leader identifies a major AUU initiated proteoform. Open Biol. 2016;6: pubmed 出版商
  • 免疫印迹; 大鼠; 图 1
Guo Q, Li X, Han H, Li C, Liu S, Gao W, et al. Histone Lysine Methylation in TGF-?1 Mediated p21 Gene Expression in Rat Mesangial Cells. Biomed Res Int. 2016;2016:6927234 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
van Ree J, Nam H, Jeganathan K, Kanakkanthara A, van Deursen J. Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes. Nat Cell Biol. 2016;18:814-21 pubmed 出版商
  • 免疫印迹; 小鼠; 图 9b
Lee S, Kim H, Kim K, Lee H, Lee S, Lee D. Arhgap17, a RhoGTPase activating protein, regulates mucosal and epithelial barrier function in the mouse colon. Sci Rep. 2016;6:26923 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Schütz I, López Hernández T, Gao Q, Puchkov D, Jabs S, Nordmeyer D, et al. Lysosomal Dysfunction Caused by Cellular Accumulation of Silica Nanoparticles. J Biol Chem. 2016;291:14170-84 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 1
Hudish L, Galati D, Ravanelli A, Pearson C, Huang P, Appel B. miR-219 regulates neural progenitors by dampening apical Par protein-dependent Hedgehog signaling. Development. 2016;143:2292-304 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 2
Tatsuno T, Nakamura Y, Ma S, Tomosugi N, Ishigaki Y. Nonsense-mediated mRNA decay factor Upf2 exists in both the nucleoplasm and the cytoplasm. Mol Med Rep. 2016;14:655-60 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000; 图 2
Rodríguez Jiménez F, Alastrue A, Stojkovic M, Erceg S, Moreno Manzano V. Connexin 50 modulates Sox2 expression in spinal-cord-derived ependymal stem/progenitor cells. Cell Tissue Res. 2016;365:295-307 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 4
Wang J, Hu K, Guo J, Cheng F, Lv J, Jiang W, et al. Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK. Nat Commun. 2016;7:11363 pubmed 出版商
  • 免疫印迹; 人类; 图 3c
Ranjan A, Srivastava S. Penfluridol suppresses pancreatic tumor growth by autophagy-mediated apoptosis. Sci Rep. 2016;6:26165 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Lin S, Wang B, Lin C, Chien P, Wu Y, Ko J, et al. Chidamide alleviates TGF-?-induced epithelial-mesenchymal transition in lung cancer cell lines. Mol Biol Rep. 2016;43:687-95 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Ferrán B, Martí Pàmies I, Alonso J, Rodríguez Calvo R, Aguiló S, Vidal F, et al. The nuclear receptor NOR-1 regulates the small muscle protein, X-linked (SMPX) and myotube differentiation. Sci Rep. 2016;6:25944 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Tsai L, Chang Y, Lee M, Chang Y, Hwang P, Huang Y, et al. Biphasic and Stage-Associated Expression of CPEB4 in Hepatocellular Carcinoma. PLoS ONE. 2016;11:e0155025 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Kant R, Yen C, Lu C, Lin Y, Li J, Chen Y. Identification of 1,2,3,4,6-Penta-O-galloyl-?-d-glucopyranoside as a Glycine N-Methyltransferase Enhancer by High-Throughput Screening of Natural Products Inhibits Hepatocellular Carcinoma. Int J Mol Sci. 2016;17: pubmed 出版商
  • 免疫印迹; 小鼠; 图 9
Vorvis C, Hatziapostolou M, Mahurkar Joshi S, Koutsioumpa M, Williams J, Donahue T, et al. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. Am J Physiol Gastrointest Liver Physiol. 2016;310:G1124-37 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 3
O Santos A, Parrini M, Camonis J. RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases. PLoS ONE. 2016;11:e0154840 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Taniguchi T, Iizumi Y, Watanabe M, Masuda M, Morita M, Aono Y, et al. Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer. Cell Death Dis. 2016;7:e2211 pubmed 出版商
  • 免疫印迹; 小鼠; 1:50,000; 图 1
Walter C, Clemens L, Müller A, Fallier Becker P, Proikas Cezanne T, Riess O, et al. Activation of AMPK-induced autophagy ameliorates Huntington disease pathology in vitro. Neuropharmacology. 2016;108:24-38 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 2
Shearn C, Orlicky D, McCullough R, Jiang H, Maclean K, Mercer K, et al. Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage. PLoS ONE. 2016;11:e0154152 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Zhu H, Bai W, Liu J, Zheng Z, Guan H, Zhou Q, et al. Up-regulation of FGFBP1 signaling contributes to miR-146a-induced angiogenesis in human umbilical vein endothelial cells. Sci Rep. 2016;6:25272 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Beard J, Tenga A, Hills J, Hoyer J, Cherian M, Wang Y, et al. The orphan nuclear receptor NR4A2 is part of a p53-microRNA-34 network. Sci Rep. 2016;6:25108 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Choudhury S, Fitzpatrick Z, Harris A, Maitland S, Ferreira J, Zhang Y, et al. In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy. Mol Ther. 2016;24:1247-57 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
De Boeck M, Cui C, Mulder A, Jost C, Ikeno S, Ten Dijke P. Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model. Sci Rep. 2016;6:24968 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 3
Rios A, Fu N, Jamieson P, Pal B, Whitehead L, Nicholas K, et al. Essential role for a novel population of binucleated mammary epithelial cells in lactation. Nat Commun. 2016;7:11400 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Rebolleda N, Losada Fernandez I, Perez Chacon G, Castejon R, Rosado S, Morado M, et al. Synergistic Activity of Deguelin and Fludarabine in Cells from Chronic Lymphocytic Leukemia Patients and in the New Zealand Black Murine Model. PLoS ONE. 2016;11:e0154159 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 3
van Loon E, Little R, Prehar S, Bindels R, Cartwright E, Hoenderop J. Calcium Extrusion Pump PMCA4: A New Player in Renal Calcium Handling?. PLoS ONE. 2016;11:e0153483 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Tasdemir N, Banito A, Roe J, Alonso Curbelo D, Camiolo M, Tschaharganeh D, et al. BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance. Cancer Discov. 2016;6:612-29 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000; 图 s5
Li Z, Hodgkinson T, Gothard E, Boroumand S, Lamb R, Cummins I, et al. Epidermal Notch1 recruits RORγ(+) group 3 innate lymphoid cells to orchestrate normal skin repair. Nat Commun. 2016;7:11394 pubmed 出版商
  • 免疫印迹; fruit fly ; 1:5000
Kwenda L, Collins C, Dattoli A, Dunleavy E. Nucleolar activity and CENP-C regulate CENP-A and CAL1 availability for centromere assembly in meiosis. Development. 2016;143:1400-12 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Cao Y, Liang H, Zhang F, Luan Z, Zhao S, Wang X, et al. Prohibitin overexpression predicts poor prognosis and promotes cell proliferation and invasion through ERK pathway activation in gallbladder cancer. J Exp Clin Cancer Res. 2016;35:68 pubmed 出版商
  • 免疫印迹; 大鼠; 图 1
Lauterborn J, Kramar E, Rice J, Babayan A, Cox C, Karsten C, et al. Cofilin Activation Is Temporally Associated with the Cessation of Growth in the Developing Hippocampus. Cereb Cortex. 2017;27:2640-2651 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Zattas D, Berk J, Kreft S, Hochstrasser M. A Conserved C-terminal Element in the Yeast Doa10 and Human MARCH6 Ubiquitin Ligases Required for Selective Substrate Degradation. J Biol Chem. 2016;291:12105-18 pubmed 出版商
  • 免疫组化; 小鼠; 图 1
Hobbs R, Batazzi A, Han M, Coulombe P. Loss of Keratin 17 induces tissue-specific cytokine polarization and cellular differentiation in HPV16-driven cervical tumorigenesis in vivo. Oncogene. 2016;35:5653-5662 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 6
Bueno C, Tabares Seisdedos R, Moraleda J, Martinez S. Rett Syndrome Mutant Neural Cells Lacks MeCP2 Immunoreactive Bands. PLoS ONE. 2016;11:e0153262 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 2
Caviness J, Lue L, Hentz J, Schmitz C, Adler C, Shill H, et al. Cortical phosphorylated α-Synuclein levels correlate with brain wave spectra in Parkinson's disease. Mov Disord. 2016;31:1012-9 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 2
Martínez M, Ubeda A, Moreno J, Trillo M. Power Frequency Magnetic Fields Affect the p38 MAPK-Mediated Regulation of NB69 Cell Proliferation Implication of Free Radicals. Int J Mol Sci. 2016;17:510 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Xing M, Wang X, Chi Y, Zhou D. Gene therapy for colorectal cancer using adenovirus-mediated full-length antibody, cetuximab. Oncotarget. 2016;7:28262-72 pubmed 出版商
  • 免疫印迹; 人类; 1:40,000; 图 2
Brown P, Gascoyne D, Lyne L, Spearman H, Felce S, McFadden N, et al. N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells. Haematologica. 2016;101:861-71 pubmed 出版商
  • 免疫印迹; 人类
O Neill K, Huang K, Zhang J, Chen Y, Luo X. Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane. Genes Dev. 2016;30:973-88 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Hall A, Lu W, Godfrey J, Antonov A, Paicu C, Moxon S, et al. The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration. Cell Death Dis. 2016;7:e2184 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 8
Canton J, Schlam D, Breuer C, Gutschow M, Glogauer M, Grinstein S. Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages. Nat Commun. 2016;7:11284 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Yosef R, Pilpel N, Tokarsky Amiel R, Biran A, Ovadya Y, Cohen S, et al. Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL. Nat Commun. 2016;7:11190 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Foot N, Gembus K, MacKenzie K, Kumar S. Ndfip2 is a potential regulator of the iron transporter DMT1 in the liver. Sci Rep. 2016;6:24045 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Aizawa S, Fujiwara Y, Contu V, Hase K, Takahashi M, Kikuchi H, et al. Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes. Autophagy. 2016;12:565-78 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Lee Y, Lee S, Lee C, Kim S, Song Y, Yoon M, et al. Association between betatrophin/ANGPTL8 and non-alcoholic fatty liver disease: animal and human studies. Sci Rep. 2016;6:24013 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1
Rhee M, Lee S, Kim J, Ham D, Park H, Yang H, et al. Preadipocyte factor 1 induces pancreatic ductal cell differentiation into insulin-producing cells. Sci Rep. 2016;6:23960 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1
Hernández Bule M, Martinez Botas J, Trillo M, Paíno C, Ubeda A. Antiadipogenic effects of subthermal electric stimulation at 448 kHz on differentiating human mesenchymal stem cells. Mol Med Rep. 2016;13:3895-903 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1
Ma B, Cheng H, Gao R, Mu C, Chen L, Wu S, et al. Zyxin-Siah2-Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways. Nat Commun. 2016;7:11123 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Riggle K, Riehle K, Kenerson H, Turnham R, Homma M, Kazami M, et al. Enhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinoma. Pediatr Res. 2016;80:110-8 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Starokadomskyy P, Gemelli T, Rios J, Xing C, Wang R, Li H, et al. DNA polymerase-? regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol. 2016;17:495-504 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 7
Woodfield S, Guo R, Liu Y, Major A, Hollingsworth E, Indiviglio S, et al. Neuroblastoma patient outcomes, tumor differentiation, and ERK activation are correlated with expression levels of the ubiquitin ligase UBE4B. Genes Cancer. 2016;7:13-26 pubmed
  • 免疫印迹; 人类; 1:5000; 图 3
Ziegler C, Eisenhauer P, Bruce E, Weir M, King B, Klaus J, et al. The Lymphocytic Choriomeningitis Virus Matrix Protein PPXY Late Domain Drives the Production of Defective Interfering Particles. PLoS Pathog. 2016;12:e1005501 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000; 图 9
  • 免疫印迹; 大鼠; 1:3000; 图 2
Viringipurampeer I, Metcalfe A, Bashar A, Sivak O, Yanai A, Mohammadi Z, et al. NLRP3 inflammasome activation drives bystander cone photoreceptor cell death in a P23H rhodopsin model of retinal degeneration. Hum Mol Genet. 2016;25:1501-16 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 2
Chan Y, Gack M. A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity. Nat Immunol. 2016;17:523-30 pubmed 出版商
  • 免疫组化; 人类; 图 1
  • 免疫印迹; 人类; 1:1000; 图 1
Galán M, Varona S, Orriols M, Rodríguez J, Aguiló S, Dilmé J, et al. Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors. Dis Model Mech. 2016;9:541-52 pubmed 出版商
  • 免疫印迹; 人类; 图 5
German P, Bai S, Liu X, Sun M, Zhou L, Kalra S, et al. Phosphorylation-dependent cleavage regulates von Hippel Lindau proteostasis and function. Oncogene. 2016;35:4973-80 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Nishida Fukuda H, Araki R, Shudou M, Okazaki H, Tomono Y, Nakayama H, et al. Ectodomain Shedding of Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE-1) Is Induced by Vascular Endothelial Growth Factor A (VEGF-A). J Biol Chem. 2016;291:10490-500 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 4
  • 免疫印迹; 犬; 1:5000; 图 1
Bartuzi P, Billadeau D, Favier R, Rong S, Dekker D, Fedoseienko A, et al. CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL. Nat Commun. 2016;7:10961 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Acharya M, Sokolovska A, Tam J, Conway K, Stefani C, Raso F, et al. αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells. Nat Commun. 2016;7:10917 pubmed 出版商
  • 免疫印迹; 人类; 1:12,000; 图 1
Pavlides S, Lecanda J, Daubriac J, Pandya U, Gama P, Blank S, et al. TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth. Cell Cycle. 2016;15:931-47 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Mitxelena J, Apraiz A, Vallejo Rodríguez J, Malumbres M, Zubiaga A. E2F7 regulates transcription and maturation of multiple microRNAs to restrain cell proliferation. Nucleic Acids Res. 2016;: pubmed
  • 免疫印迹; 斑马鱼; 1:1000; 图 3
Hirth S, Bühler A, Bührdel J, Rudeck S, Dahme T, Rottbauer W, et al. Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart. PLoS ONE. 2016;11:e0150323 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 3
Shukla P, Chaudhry K, Mir H, Gangwar R, Yadav N, Manda B, et al. Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation. BMC Cancer. 2016;16:189 pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 7
Gdynia G, Sauer S, Kopitz J, Fuchs D, Duglova K, Ruppert T, et al. The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration. Nat Commun. 2016;7:10764 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 1
Nagase M, Kurihara H, Aiba A, Young M, Sakai T. Deletion of Rac1GTPase in the Myeloid Lineage Protects against Inflammation-Mediated Kidney Injury in Mice. PLoS ONE. 2016;11:e0150886 pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 1
Tao Y, Hu K, Tan F, Zhang S, Zhou M, Luo J, et al. SH3-domain binding protein 1 in the tumor microenvironment promotes hepatocellular carcinoma metastasis through WAVE2 pathway. Oncotarget. 2016;7:18356-70 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Chen R, Du Y, Han P, Wang H, Liang F, Feng G, et al. ISG15 predicts poor prognosis and promotes cancer stem cell phenotype in nasopharyngeal carcinoma. Oncotarget. 2016;7:16910-22 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Köhler C, Koalick D, Fabricius A, Parplys A, Borgmann K, Pospiech H, et al. Cdc45 is limiting for replication initiation in humans. Cell Cycle. 2016;15:974-85 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Fong S, Lin H, Wu M, Chen C, Huang Y. CPEB3 Deficiency Elevates TRPV1 Expression in Dorsal Root Ganglia Neurons to Potentiate Thermosensation. PLoS ONE. 2016;11:e0148491 pubmed 出版商
  • 免疫印迹; 人类; 图 s4
Bistulfi G, Affronti H, Foster B, Karasik E, Gillard B, Morrison C, et al. The essential role of methylthioadenosine phosphorylase in prostate cancer. Oncotarget. 2016;7:14380-93 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 2
Swetzig W, Wang J, Das G. Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer. Oncotarget. 2016;7:16049-69 pubmed 出版商
  • 免疫印迹; 大鼠; 1:10,000; 图 1
Wilson N, Titus D, Oliva A, Furones C, Atkins C. Traumatic Brain Injury Upregulates Phosphodiesterase Expression in the Hippocampus. Front Syst Neurosci. 2016;10:5 pubmed 出版商
  • 免疫印迹; 鸡; 图 1
Williams A, Maman Y, Alinikula J, Schatz D. Bcl6 Is Required for Somatic Hypermutation and Gene Conversion in Chicken DT40 Cells. PLoS ONE. 2016;11:e0149146 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Burgy O, Wettstein G, Bellaye P, Decologne N, Racoeur C, Goirand F, et al. Deglycosylated bleomycin has the antitumor activity of bleomycin without pulmonary toxicity. Sci Transl Med. 2016;8:326ra20 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000; 图 2
Rubattu S, Di Castro S, Schulz H, Geurts A, Cotugno M, Bianchi F, et al. Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease. J Am Heart Assoc. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 图 1
Hatori Y, Yan Y, Schmidt K, Furukawa E, Hasan N, Yang N, et al. Neuronal differentiation is associated with a redox-regulated increase of copper flow to the secretory pathway. Nat Commun. 2016;7:10640 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Wang J, Goetsch L, Tucker L, Zhang Q, Gonzalez A, Vaidya K, et al. Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification. BMC Cancer. 2016;16:105 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Nyhan M, O Donovan T, Boersma A, Wiemer E, McKenna S. MiR-193b promotes autophagy and non-apoptotic cell death in oesophageal cancer cells. BMC Cancer. 2016;16:101 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 2
Lehmann W, Mossmann D, Kleemann J, Mock K, Meisinger C, Brummer T, et al. ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types. Nat Commun. 2016;7:10498 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Lei Y, Kansy B, Li J, Cong L, Liu Y, Trivedi S, et al. EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1-TUFM protein complex. Oncogene. 2016;35:4698-707 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
  • 免疫印迹; 人类; 图 4
Kim D, Helfman D. Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling. Oncogene. 2016;35:4495-508 pubmed 出版商
  • 免疫印迹; 小鼠; 1:20,000; 图 7
Currie S, Gwyer Findlay E, McFarlane A, Fitch P, Böttcher B, Colegrave N, et al. Cathelicidins Have Direct Antiviral Activity against Respiratory Syncytial Virus In Vitro and Protective Function In Vivo in Mice and Humans. J Immunol. 2016;196:2699-710 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000; 图 6
Merdzo I, Rutkai I, Tokés T, Sure V, Katakam P, Busija D. The mitochondrial function of the cerebral vasculature in insulin-resistant Zucker obese rats. Am J Physiol Heart Circ Physiol. 2016;310:H830-8 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 3
Estruch S, Graham S, Deriziotis P, Fisher S. The language-related transcription factor FOXP2 is post-translationally modified with small ubiquitin-like modifiers. Sci Rep. 2016;6:20911 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 2
Wadosky K, Berthiaume J, Tang W, Zungu M, Portman M, Gerdes A, et al. MuRF1 mono-ubiquitinates TRα to inhibit T3-induced cardiac hypertrophy in vivo. J Mol Endocrinol. 2016;56:273-90 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Su R, Strug M, Jeong J, Miele L, Fazleabas A. Aberrant activation of canonical Notch1 signaling in the mouse uterus decreases progesterone receptor by hypermethylation and leads to infertility. Proc Natl Acad Sci U S A. 2016;113:2300-5 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6c
Liu Y, Takahashi Y, Desai N, Zhang J, Serfass J, Shi Y, et al. Bif-1 deficiency impairs lipid homeostasis and causes obesity accompanied by insulin resistance. Sci Rep. 2016;6:20453 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
Nawaz M, Giarda E, Bedogni F, La Montanara P, Ricciardi S, Ciceri D, et al. CDKL5 and Shootin1 Interact and Concur in Regulating Neuronal Polarization. PLoS ONE. 2016;11:e0148634 pubmed 出版商
  • 免疫印迹; 人类; 图 4
De Toni E, Ziesch A, Rizzani A, Török H, Hocke S, Lü S, et al. Inactivation of BRCA2 in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptor-mediated apoptosis. Oncotarget. 2016;7:9477-90 pubmed 出版商
  • 免疫印迹; 人类; 1:50,000; 图 2
Regina C, Compagnone M, Peschiaroli A, Lena A, Annicchiarico Petruzzelli M, Piro M, et al. Setdb1, a novel interactor of ΔNp63, is involved in breast tumorigenesis. Oncotarget. 2016;7:28836-48 pubmed 出版商
  • 免疫印迹; 斑马鱼; 1:1000; 图 5
Bühler A, Kustermann M, Bummer T, Rottbauer W, Sandri M, Just S. Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish. Int J Mol Sci. 2016;17: pubmed 出版商
  • 免疫印迹; 人类; 图 2
Fujiwara S, Ohashi K, Mashiko T, Kondo H, Mizuno K. Interplay between Solo and keratin filaments is crucial for mechanical force-induced stress fiber reinforcement. Mol Biol Cell. 2016;27:954-66 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1
Madonna R, Giovannelli G, Confalone P, Renna F, Geng Y, De Caterina R. High glucose-induced hyperosmolarity contributes to COX-2 expression and angiogenesis: implications for diabetic retinopathy. Cardiovasc Diabetol. 2016;15:18 pubmed 出版商
  • 免疫印迹; 人类; 图 s5b
Lin L, Jiang P, Park J, Wang J, Lu Z, Lam M, et al. The contribution of Alu exons to the human proteome. Genome Biol. 2016;17:15 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 3
Kishi N, MacDonald J, Ye J, Molyneaux B, Azim E, Macklis J. Reduction of aberrant NF-κB signalling ameliorates Rett syndrome phenotypes in Mecp2-null mice. Nat Commun. 2016;7:10520 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Díaz Barreiro A, Bernal Quirós M, Georg I, Marañón C, Alarcón Riquelme M, Castillejo López C. The SLE variant Ala71Thr of BLK severely decreases protein abundance and binding to BANK1 through impairment of the SH3 domain function. Genes Immun. 2016;17:128-38 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 3
Long C, Guo W, Zhou H, Wang J, Wang H, Sun X. Triptolide decreases expression of latency-associated nuclear antigen 1 and reduces viral titers in Kaposi's sarcoma-associated and herpesvirus-related primary effusion lymphoma cells. Int J Oncol. 2016;48:1519-30 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 5a
Bothur E, Raifer H, Haftmann C, Stittrich A, Brüstle A, Brenner D, et al. Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1. Nat Commun. 2015;6:8576 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Bindesbøll C, Tan S, Bott D, Cho T, Tamblyn L, MacPherson L, et al. TCDD-inducible poly-ADP-ribose polymerase (TIPARP/PARP7) mono-ADP-ribosylates and co-activates liver X receptors. Biochem J. 2016;473:899-910 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Zhang G, Chan B, Samarina N, Abere B, Weidner Glunde M, Buch A, et al. Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS. Proc Natl Acad Sci U S A. 2016;113:E1034-43 pubmed 出版商
  • 免疫印迹; 小鼠
Luo C, Liao W, Dadi S, Toure A, Li M. Graded Foxo1 activity in Treg cells differentiates tumour immunity from spontaneous autoimmunity. Nature. 2016;529:532-6 pubmed 出版商
  • 免疫印迹; domestic rabbit; 1:5000; 图 1
Santhanam A, Torricelli A, Wu J, Marino G, Wilson S. Differential expression of epithelial basement membrane components nidogens and perlecan in corneal stromal cells in vitro. Mol Vis. 2015;21:1318-27 pubmed
  • 免疫印迹; 小鼠; 图 3
Korwitz A, Merkwirth C, Richter Dennerlein R, Tröder S, Sprenger H, Quirós P, et al. Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria. J Cell Biol. 2016;212:157-66 pubmed 出版商
  • 免疫印迹; 犬; 1:4000; 图 1
  • 免疫印迹; 人类; 1:4000; 图 2
Tien S, Lee H, Yang Y, Lin M, Chen Y, Chang Z. The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42. Nat Commun. 2016;7:10420 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Schirmer M, Trentin L, Queudeville M, Seyfried F, Demir S, Tausch E, et al. Intrinsic and chemo-sensitizing activity of SMAC-mimetics on high-risk childhood acute lymphoblastic leukemia. Cell Death Dis. 2016;7:e2052 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Dieckmann N, Hackmann Y, Aricò M, Griffiths G. Munc18-2 is required for Syntaxin 11 Localization on the Plasma Membrane in Cytotoxic T-Lymphocytes. Traffic. 2015;16:1330-41 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
  • 免疫印迹; 人类; 图 1
Wang S, Ni H, Dorko K, Kumer S, Schmitt T, Nawabi A, et al. Increased hepatic receptor interacting protein kinase 3 expression due to impaired proteasomal functions contributes to alcohol-induced steatosis and liver injury. Oncotarget. 2016;7:17681-98 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000
Ketel K, Krauss M, Nicot A, Puchkov D, Wieffer M, Müller R, et al. A phosphoinositide conversion mechanism for exit from endosomes. Nature. 2016;529:408-12 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1
Zhang C, Liu J, Zhao Y, Yue X, Zhu Y, Wang X, et al. Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis. elife. 2016;5:e10727 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3e
Liu H, Shi H, Huang F, Peterson K, Wu H, Lan Y, et al. Astragaloside IV inhibits microglia activation via glucocorticoid receptor mediated signaling pathway. Sci Rep. 2016;6:19137 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Li N, Dhar S, Chen T, Kan P, Wei Y, Kim J, et al. JARID1D Is a Suppressor and Prognostic Marker of Prostate Cancer Invasion and Metastasis. Cancer Res. 2016;76:831-43 pubmed 出版商
  • 免疫印迹; 人类; 图 6c
Hérate C, Ramdani G, Grant N, Marion S, Gasman S, Niedergang F, et al. Phospholipid Scramblase 1 Modulates FcR-Mediated Phagocytosis in Differentiated Macrophages. PLoS ONE. 2016;11:e0145617 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 3
Vacca V, Marinelli S, Pieroni L, Urbani A, Luvisetto S, Pavone F. 17beta-estradiol counteracts neuropathic pain: a behavioural, immunohistochemical, and proteomic investigation on sex-related differences in mice. Sci Rep. 2016;6:18980 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2b
Chen Y, Statt S, Wu R, Chang H, Liao J, Wang C, et al. High mobility group box 1-induced epithelial mesenchymal transition in human airway epithelial cells. Sci Rep. 2016;6:18815 pubmed 出版商
  • 免疫印迹; 人类; 1:20,000; 图 6
Piggin C, Roden D, Gallego Ortega D, Lee H, Oakes S, Ormandy C. ELF5 isoform expression is tissue-specific and significantly altered in cancer. Breast Cancer Res. 2016;18:4 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Liberante F, Pouryahya T, McMullin M, Zhang S, Mills K. Identification and validation of the dopamine agonist bromocriptine as a novel therapy for high-risk myelodysplastic syndromes and secondary acute myeloid leukemia. Oncotarget. 2016;7:6609-19 pubmed 出版商
  • 免疫印迹; 人类; 1:8000; 图 4
Lee S, Frattini V, Bansal M, Castano A, Sherman D, Hutchinson K, et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016;529:172-7 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Rassoolzadeh H, Coucoravas C, Farnebo M. The proximity ligation assay reveals that at DNA double-strand breaks WRAP53β associates with γH2AX and controls interactions between RNF8 and MDC1. Nucleus. 2015;6:417-24 pubmed 出版商
  • 免疫印迹; 人类; 1:20,000; 图 1
Zayas M, Long G, Madan V, Bartenschlager R. Coordination of Hepatitis C Virus Assembly by Distinct Regulatory Regions in Nonstructural Protein 5A. PLoS Pathog. 2016;12:e1005376 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Han M, Lee D, Woo S, Seo B, Min K, Kim S, et al. Galangin sensitizes TRAIL-induced apoptosis through down-regulation of anti-apoptotic proteins in renal carcinoma Caki cells. Sci Rep. 2016;6:18642 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Clark D, Mei Y, Sun S, Zhang H, Yang A, Mao L. Glycoproteomic Approach Identifies KRAS as a Positive Regulator of CREG1 in Non-small Cell Lung Cancer Cells. Theranostics. 2016;6:65-77 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000; 图 2
Wang Q, Wang D, Yan G, Sun L, Tang C. TRPC6 is required for hypoxia-induced basal intracellular calcium concentration elevation, and for the proliferation and migration of rat distal pulmonary venous smooth muscle cells. Mol Med Rep. 2016;13:1577-85 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Gallego Ortega D, Ledger A, Roden D, Law A, Magenau A, Kikhtyak Z, et al. ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells. PLoS Biol. 2015;13:e1002330 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 2
Xu Y, Wu D, Zheng W, Yu F, Yang F, Yao Y, et al. Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. Oncotarget. 2016;7:6146-58 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Noh H, Hah Y, Ha J, Kang M, Zada S, Rha S, et al. Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity. Oncotarget. 2016;7:4632-46 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Li R, Liao G, Nirujogi R, Pinto S, Shaw P, Huang T, et al. Phosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic Signaling. PLoS Pathog. 2015;11:e1005346 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Choudhury S, Harris A, Cabral D, Keeler A, Sapp E, Ferreira J, et al. Widespread Central Nervous System Gene Transfer and Silencing After Systemic Delivery of Novel AAV-AS Vector. Mol Ther. 2016;24:726-35 pubmed 出版商
  • 免疫印迹; 人类; 1:8000; 图 5
Bartosch C, Monteiro Reis S, Almeida Rios D, Vieira R, Castro A, Moutinho M, et al. Assessing sirtuin expression in endometrial carcinoma and non-neoplastic endometrium. Oncotarget. 2016;7:1144-54 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 1
Khoutorsky A, Bonin R, Sorge R, Gkogkas C, Pawlowski S, Jafarnejad S, et al. Translational control of nociception via 4E-binding protein 1. elife. 2015;4: pubmed 出版商
  • 免疫印迹; 小鼠; 图 s1c, d
Kamitani T, Sakaguchi H, Tamura A, Miyashita T, Yamazaki Y, Tokumasu R, et al. Deletion of Tricellulin Causes Progressive Hearing Loss Associated with Degeneration of Cochlear Hair Cells. Sci Rep. 2015;5:18402 pubmed 出版商
  • 免疫沉淀; 大鼠; 1:1000; 图 1
  • 免疫细胞化学; 大鼠; 图 3
  • 免疫印迹; 大鼠; 1:1000; 图 1
Gong X, Tan M, Gao Y, Chen K, Guo G. CRMP‑5 interacts with actin to regulate neurite outgrowth. Mol Med Rep. 2016;13:1179-85 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 5
Wille C, Nawandar D, Henning A, Ma S, Oetting K, Lee D, et al. 5-hydroxymethylation of the EBV genome regulates the latent to lytic switch. Proc Natl Acad Sci U S A. 2015;112:E7257-65 pubmed 出版商
  • 免疫印迹; 牛; 图 3
Arévalo Turrubiarte M, Perruchot M, Finot L, Mayeur F, Dessauge F. Phenotypic and functional characterization of two bovine mammary epithelial cell lines in 2D and 3D models. Am J Physiol Cell Physiol. 2016;310:C348-56 pubmed 出版商
  • 免疫印迹; 人类; 图 5A
Yu F, Shen X, Fan L, Yu Z. Analysis of histone modifications at human ribosomal DNA in liver cancer cell. Sci Rep. 2015;5:18100 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 1b
Ageta Ishihara N, Yamazaki M, Konno K, Nakayama H, Abe M, Hashimoto K, et al. A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance. Nat Commun. 2015;6:10090 pubmed 出版商
  • 免疫印迹; 人类; 图 s10a
Bowser J, Blackburn M, Shipley G, Molina J, Dunner K, Broaddus R. Loss of CD73-mediated actin polymerization promotes endometrial tumor progression. J Clin Invest. 2016;126:220-38 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 5a
Aimi F, Georgiopoulou S, Kalus I, Lehner F, Hegglin A, Limani P, et al. Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult. Sci Rep. 2015;5:17705 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 2
Seidensaal K, Nollert A, Feige A, Muller M, Fleming T, Gunkel N, et al. Impaired aldehyde dehydrogenase 1 subfamily member 2A-dependent retinoic acid signaling is related with a mesenchymal-like phenotype and an unfavorable prognosis of head and neck squamous cell carcinoma. Mol Cancer. 2015;14:204 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 s6a
Jimenez Mateos E, Arribas Blázquez M, Sanz Rodriguez A, Concannon C, Olivos Ore L, Reschke C, et al. microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus. Sci Rep. 2015;5:17486 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Lommel M, Trairatphisan P, Gäbler K, Laurini C, Muller A, Kaoma T, et al. L-plastin Ser5 phosphorylation in breast cancer cells and in vitro is mediated by RSK downstream of the ERK/MAPK pathway. FASEB J. 2016;30:1218-33 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Biziota E, Briasoulis E, Mavroeidis L, Marselos M, Harris A, Pappas P. Cellular and molecular effects of metronomic vinorelbine and 4-O-deacetylvinorelbine on human umbilical vein endothelial cells. Anticancer Drugs. 2016;27:216-24 pubmed 出版商
  • 免疫印迹; 人类; 图 9
Mehraein Ghomi F, Church D, Schreiber C, Weichmann A, Basu H, Wilding G. Inhibitor of p52 NF-κB subunit and androgen receptor (AR) interaction reduces growth of human prostate cancer cells by abrogating nuclear translocation of p52 and phosphorylated AR(ser81). Genes Cancer. 2015;6:428-44 pubmed
  • 免疫印迹; 人类; 图 s5
Pankow S, Bamberger C, Calzolari D, Martínez Bartolomé S, Lavallée Adam M, Balch W, et al. ∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis. Nature. 2015;528:510-6 pubmed 出版商
  • 免疫印迹; 人类; 图 1
de Jong O, van Balkom B, Gremmels H, Verhaar M. Exosomes from hypoxic endothelial cells have increased collagen crosslinking activity through up-regulation of lysyl oxidase-like 2. J Cell Mol Med. 2016;20:342-50 pubmed 出版商
  • 免疫印迹; 大鼠; 1:10,000; 图 3
Fang M, Yuan Y, Rangarajan P, Lu J, Wu Y, Wang H, et al. Scutellarin regulates microglia-mediated TNC1 astrocytic reaction and astrogliosis in cerebral ischemia in the adult rats. BMC Neurosci. 2015;16:84 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3E
Ni Y, Nagashimada M, Zhuge F, Zhan L, Nagata N, Tsutsui A, et al. Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. Sci Rep. 2015;5:17192 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
  • 免疫印迹; 人类; 图 1
Yasuda K, Takahashi M, Mori N. Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression. PLoS ONE. 2015;10:e0142943 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 1
Ferri F, Parcelier A, Petit V, Gallouet A, Lewandowski D, Dalloz M, et al. TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation. Nat Commun. 2015;6:8900 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 4
Lyu L, Whitcomb E, Jiang S, Chang M, Gu Y, Duncan M, et al. Unfolded-protein response-associated stabilization of p27(Cdkn1b) interferes with lens fiber cell denucleation, leading to cataract. FASEB J. 2016;30:1087-95 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Isernhagen A, Schilling D, Monecke S, Shah P, Elsner L, Walter L, et al. The MICA-129Met/Val dimorphism affects plasma membrane expression and shedding of the NKG2D ligand MICA. Immunogenetics. 2016;68:109-23 pubmed 出版商
  • 免疫印迹; 人类; 图 4
van Jaarsveld M, van Kuijk P, Boersma A, Helleman J, Van Ijcken W, Mathijssen R, et al. miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway. Mol Cancer. 2015;14:196 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1
Nanba K, Chen A, Turcu A, Rainey W. H295R expression of melanocortin 2 receptor accessory protein results in ACTH responsiveness. J Mol Endocrinol. 2016;56:69-76 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Lamana A, López Santalla M, Castillo González R, Ortiz A, Martín J, García Vicuña R, et al. The Minor Allele of rs7574865 in the STAT4 Gene Is Associated with Increased mRNA and Protein Expression. PLoS ONE. 2015;10:e0142683 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 4d
Fridriksdottir A, Kim J, Villadsen R, Klitgaard M, Hopkinson B, Petersen O, et al. Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture. Nat Commun. 2015;6:8786 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Ninkina N, Connor Robson N, Ustyugov A, Tarasova T, Shelkovnikova T, Buchman V. A novel resource for studying function and dysfunction of α-synuclein: mouse lines for modulation of endogenous Snca gene expression. Sci Rep. 2015;5:16615 pubmed 出版商
  • 免疫印迹; 人类; 图 1B
  • 免疫印迹; 小鼠; 图 1B
He X, Wang L, Yan J, Yuan C, Witze E, Hua X. Menin localization in cell membrane compartment. Cancer Biol Ther. 2016;17:114-22 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Funauchi Y, Tanikawa C, Yi Lo P, Mori J, Daigo Y, Takano A, et al. Regulation of iron homeostasis by the p53-ISCU pathway. Sci Rep. 2015;5:16497 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Scherer M, Otto V, Stump J, Klingl S, Müller R, Reuter N, et al. Characterization of Recombinant Human Cytomegaloviruses Encoding IE1 Mutants L174P and 1-382 Reveals that Viral Targeting of PML Bodies Perturbs both Intrinsic and Innate Immune Responses. J Virol. 2016;90:1190-205 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Seidel C, Schnekenburger M, Mazumder A, Teiten M, Kirsch G, Dicato M, et al. 4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer. Biochem Pharmacol. 2016;99:31-52 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 4
Buczek M, Miles A, Green W, Johnson C, Boocock D, Pockley A, et al. Cytoplasmic PML promotes TGF-β-associated epithelial-mesenchymal transition and invasion in prostate cancer. Oncogene. 2016;35:3465-75 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
Hatanaka Y, Watase K, Wada K, Nagai Y. Abnormalities in synaptic dynamics during development in a mouse model of spinocerebellar ataxia type 1. Sci Rep. 2015;5:16102 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Xiao D, Ren P, Su H, Yue M, Xiu R, Hu Y, et al. Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2. Oncotarget. 2015;6:40655-66 pubmed 出版商
  • 免疫印迹; 大鼠; 图 5a
  • 免疫印迹; 小鼠; 图 2b
  • 免疫印迹; 人类; 图 3b
Yu D, Makkar G, Dong T, Strickland D, Sarkar R, Monahan T. MARCKS Signaling Differentially Regulates Vascular Smooth Muscle and Endothelial Cell Proliferation through a KIS-, p27kip1- Dependent Mechanism. PLoS ONE. 2015;10:e0141397 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 2
Zhao E, Maj T, Kryczek I, Li W, Wu K, Zhao L, et al. Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction. Nat Immunol. 2016;17:95-103 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Hunter J, Butterworth J, Zhao B, Sellier H, Campbell K, Thomas H, et al. The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma. Oncogene. 2016;35:3476-84 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Shimura D, Kusakari Y, Sasano T, Nakashima Y, Nakai G, Jiao Q, et al. Heterozygous deletion of sarcolipin maintains normal cardiac function. Am J Physiol Heart Circ Physiol. 2016;310:H92-103 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 ev3
Fernández Santiago R, Carballo Carbajal I, Castellano G, Torrent R, Richaud Y, Sánchez Danés A, et al. Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients. EMBO Mol Med. 2015;7:1529-46 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Hadzic E, Catillon M, Halavatyi A, Medves S, Van Troys M, Moes M, et al. Delineating the Tes Interaction Site in Zyxin and Studying Cellular Effects of Its Disruption. PLoS ONE. 2015;10:e0140511 pubmed 出版商
  • 免疫印迹; 人类; 图 1
  • 免疫印迹; 小鼠; 图 1
Eiseler T, Wille C, Koehler C, Illing A, Seufferlein T. Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion. J Biol Chem. 2016;291:462-77 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Knoll M, Macher Goeppinger S, Kopitz J, Duensing S, Pahernik S, Hohenfellner M, et al. The ribosomal protein S6 in renal cell carcinoma: functional relevance and potential as biomarker. Oncotarget. 2016;7:418-32 pubmed 出版商
  • 免疫印迹; 大鼠; 1:20,000; 图 1
Chidlow G, Wood J, Knoops B, Casson R. Expression and distribution of peroxiredoxins in the retina and optic nerve. Brain Struct Funct. 2016;221:3903-3925 pubmed
  • 免疫印迹; 人类; 1:20,000; 图 st3
Brown P, Wong K, Felce S, Lyne L, Spearman H, Soilleux E, et al. FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas. Leukemia. 2016;30:605-16 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1
Slemmons K, Crose L, Rudzinski E, Bentley R, Linardic C. Role of the YAP Oncoprotein in Priming Ras-Driven Rhabdomyosarcoma. PLoS ONE. 2015;10:e0140781 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Tonsing Carter E, Bailey B, Saadatzadeh M, Ding J, Wang H, Sinn A, et al. Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model. Mol Cancer Ther. 2015;14:2850-63 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1
Lauková J, Kozubík A, Hofmanová J, Nekvindová J, Sova P, Moyer M, et al. Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells. PLoS ONE. 2015;10:e0141020 pubmed 出版商
  • 免疫印迹; pigs ; 图 6
Du J, Ge X, Liu Y, Jiang P, Wang Z, Zhang R, et al. Targeting Swine Leukocyte Antigen Class I Molecules for Proteasomal Degradation by the nsp1α Replicase Protein of the Chinese Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Strain JXwn06. J Virol. 2016;90:682-93 pubmed 出版商
  • 免疫印迹; 小鼠; 1:15,000; 图 3
  • 免疫印迹; 人类; 1:15,000; 图 s4
Slaats G, Isabella C, Kroes H, Dempsey J, Gremmels H, Monroe G, et al. MKS1 regulates ciliary INPP5E levels in Joubert syndrome. J Med Genet. 2016;53:62-72 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Graindorge D, Martineau S, Machon C, Arnoux P, Guitton J, Francesconi S, et al. Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication. PLoS ONE. 2015;10:e0140645 pubmed 出版商
  • 免疫印迹; 人类; 图 8e
Hochrainer K, Pejanovic N, Olaseun V, Zhang S, Iadecola C, Anrather J. The ubiquitin ligase HERC3 attenuates NF-κB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradation. Nucleic Acids Res. 2015;43:9889-904 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Liu Z, Hu J, Liang J, Zhou A, Li M, Yan S, et al. Far upstream element-binding protein 1 is a prognostic biomarker and promotes nasopharyngeal carcinoma progression. Cell Death Dis. 2015;6:e1920 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 6
Montes M, Coiras M, Becerra S, Moreno Castro C, Mateos E, Majuelos J, et al. Functional Consequences for Apoptosis by Transcription Elongation Regulator 1 (TCERG1)-Mediated Bcl-x and Fas/CD95 Alternative Splicing. PLoS ONE. 2015;10:e0139812 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 5
Bae E, Yang N, Lee C, Kim S, Lee H, Lee S. Haploinsufficiency of cathepsin D leads to lysosomal dysfunction and promotes cell-to-cell transmission of α-synuclein aggregates. Cell Death Dis. 2015;6:e1901 pubmed 出版商
  • 免疫印迹; 人类; 图 1d
Phinney D, Di Giuseppe M, Njah J, Sala E, Shiva S, St Croix C, et al. Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs. Nat Commun. 2015;6:8472 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1
Meng Z, Moroishi T, Mottier Pavie V, Plouffe S, Hansen C, Hong A, et al. MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Nat Commun. 2015;6:8357 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Fink S, Myeroff L, Kariv R, Platzer P, Xin B, Mikkola D, et al. Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival. Oncotarget. 2015;6:30500-15 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Asai H, Ikezu S, Tsunoda S, Medalla M, Luebke J, Haydar T, et al. Depletion of microglia and inhibition of exosome synthesis halt tau propagation. Nat Neurosci. 2015;18:1584-93 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Felli N, Errico M, Pedini F, Petrini M, Puglisi R, Bellenghi M, et al. AP2α controls the dynamic balance between miR-126&126* and miR-221&222 during melanoma progression. Oncogene. 2016;35:3016-26 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Patruno A, Pesce M, Grilli A, Speranza L, Franceschelli S, De Lutiis M, et al. mTOR Activation by PI3K/Akt and ERK Signaling in Short ELF-EMF Exposed Human Keratinocytes. PLoS ONE. 2015;10:e0139644 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 4
Nawandar D, Wang A, Makielski K, Lee D, Ma S, Barlow E, et al. Differentiation-Dependent KLF4 Expression Promotes Lytic Epstein-Barr Virus Infection in Epithelial Cells. PLoS Pathog. 2015;11:e1005195 pubmed 出版商
  • 免疫印迹; 人类; 图 3c
Schmidt J, Klingler F, Proschak E, Steinhilber D, Schubert Zsilavecz M, Merk D. NSAIDs Ibuprofen, Indometacin, and Diclofenac do not interact with Farnesoid X Receptor. Sci Rep. 2015;5:14782 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 4
Hu D, Gur M, Zhou Z, Gamper A, Hung M, Fujita N, et al. Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis. Nat Commun. 2015;6:8419 pubmed 出版商
  • 免疫印迹; 人类; 图 1d
Kharaziha P, Chioureas D, Baltatzis G, Fonseca P, Rodriguez P, Gogvadze V, et al. Sorafenib-induced defective autophagy promotes cell death by necroptosis. Oncotarget. 2015;6:37066-82 pubmed 出版商
  • 免疫印迹; 人类; 图 s5
Moody P, Sayers E, Magnusson J, Alexander C, Borri P, Watson P, et al. Receptor Crosslinking: A General Method to Trigger Internalization and Lysosomal Targeting of Therapeutic Receptor:Ligand Complexes. Mol Ther. 2015;23:1888-98 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Zulliger R, Conley S, Mwoyosvi M, Stuck M, Azadi S, Naash M. SNAREs Interact with Retinal Degeneration Slow and Rod Outer Segment Membrane Protein-1 during Conventional and Unconventional Outer Segment Targeting. PLoS ONE. 2015;10:e0138508 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Xiong R, Zhou W, Siegel D, Kitson R, Freed C, Moody C, et al. A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T α-Synuclein Toxicity. Mol Pharmacol. 2015;88:1045-54 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 3
Cecchetti S, Bortolomai I, Ferri R, Mercurio L, Canevari S, Podo F, et al. Inhibition of Phosphatidylcholine-Specific Phospholipase C Interferes with Proliferation and Survival of Tumor Initiating Cells in Squamous Cell Carcinoma. PLoS ONE. 2015;10:e0136120 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Polettini J, Behnia F, Taylor B, Saade G, Taylor R, Menon R. Telomere Fragment Induced Amnion Cell Senescence: A Contributor to Parturition?. PLoS ONE. 2015;10:e0137188 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Wu L, Guo L, Liang Y, Liu X, Jiang L, Wang L. Curcumin suppresses stem-like traits of lung cancer cells via inhibiting the JAK2/STAT3 signaling pathway. Oncol Rep. 2015;34:3311-7 pubmed 出版商
  • 免疫印迹; 人类; 图 2
  • 免疫印迹; 小鼠; 图 5
Haim Y, Bluher M, Slutsky N, Goldstein N, Kloting N, Harman Boehm I, et al. Elevated autophagy gene expression in adipose tissue of obese humans: A potential non-cell-cycle-dependent function of E2F1. Autophagy. 2015;11:2074-2088 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Grootaert M, da Costa Martins P, Bitsch N, Pintelon I, De Meyer G, Martinet W, et al. Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. Autophagy. 2015;11:2014-2032 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 2
Granato M, Santarelli R, Filardi M, Gonnella R, Farina A, Torrisi M, et al. The activation of KSHV lytic cycle blocks autophagy in PEL cells. Autophagy. 2015;11:1978-1986 pubmed 出版商
  • 免疫印迹; 大鼠; 图 s2
Yao H, Ferdaus M, Zahid H, Ohara H, Nakahara T, Nabika T. Focal Ischemic Injury with Complex Middle Cerebral Artery in Stroke-Prone Spontaneously Hypertensive Rats with Loss-Of-Function in NADPH Oxidases. PLoS ONE. 2015;10:e0138551 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Yokdang N, Hatakeyama J, Wald J, Simion C, Tellez J, Chang D, et al. LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells. Oncogene. 2016;35:2932-47 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 3
Brina D, Miluzio A, Ricciardi S, Clarke K, Davidsen P, Viero G, et al. eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription. Nat Commun. 2015;6:8261 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Iriondo O, Rábano M, Domenici G, Carlevaris O, López Ruiz J, Zabalza I, et al. Distinct breast cancer stem/progenitor cell populations require either HIF1α or loss of PHD3 to expand under hypoxic conditions. Oncotarget. 2015;6:31721-39 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Ashford A, Dunkley T, Cockerill M, Rowlinson R, Baak L, Gallo R, et al. Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome. Cell Mol Life Sci. 2016;73:883-900 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1
King C, Li X, Barbachano Guerrero A, Bhaduri McIntosh S. STAT3 Regulates Lytic Activation of Kaposi's Sarcoma-Associated Herpesvirus. J Virol. 2015;89:11347-55 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Reuther C, Heinzle V, Spampatti M, Vlotides G, de Toni E, Spöttl G, et al. Cabozantinib and Tivantinib, but Not INC280, Induce Antiproliferative and Antimigratory Effects in Human Neuroendocrine Tumor Cells in vitro: Evidence for 'Off-Target' Effects Not Mediated by c-Met Inhibition. Neuroendocrinology. 2016;103:383-401 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 6l
  • 免疫印迹; 人类; 1:10,000; 图 1n
Sharma B, Kolhe R, Black S, Keller J, Mivechi N, Satyanarayana A. Inhibitor of differentiation 1 transcription factor promotes metabolic reprogramming in hepatocellular carcinoma cells. FASEB J. 2016;30:262-75 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b
Yao X, Tang Z, Fu X, Yin J, Liang Y, Li C, et al. The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination. EMBO J. 2015;34:2885-902 pubmed 出版商
  • 免疫印迹; 人类; 1:400
Chun Y, Oh H, Park M, Kim T, Chung S. Increasing Membrane Cholesterol Level Increases the Amyloidogenic Peptide by Enhancing the Expression of Phospholipase C. J Neurodegener Dis. 2013;2013:407903 pubmed 出版商
  • 免疫印迹; 人类
Chojnowski A, Ong P, Wong E, Lim J, Mutalif R, Navasankari R, et al. Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria. elife. 2015;4: pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
Barão S, Gärtner A, Leyva Díaz E, Demyanenko G, Munck S, Vanhoutvin T, et al. Antagonistic Effects of BACE1 and APH1B-γ-Secretase Control Axonal Guidance by Regulating Growth Cone Collapse. Cell Rep. 2015;12:1367-76 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Gramolelli S, Weidner Glunde M, Abere B, Viejo Borbolla A, Bala K, Rückert J, et al. Inhibiting the Recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells. PLoS Pathog. 2015;11:e1005105 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000
Lee Y, Liu C, Liao M, Sukhova G, Shirakawa J, Abdennour M, et al. Deficiency of FcϵR1 Increases Body Weight Gain but Improves Glucose Tolerance in Diet-Induced Obese Mice. Endocrinology. 2015;156:4047-58 pubmed 出版商
  • 免疫印迹; 人类; 1:50,000
Fritz H, Gustafsson A, Ljungberg B, Ceder Y, Axelson H, Dahlbäck B. The Axl-Regulating Tumor Suppressor miR-34a Is Increased in ccRCC but Does Not Correlate with Axl mRNA or Axl Protein Levels. PLoS ONE. 2015;10:e0135991 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1g
Galicia Vázquez G, Chu J, Pelletier J. eIF4AII is dispensable for miRNA-mediated gene silencing. RNA. 2015;21:1826-33 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Fan L, Peng G, Sahgal N, Fazli L, Gleave M, Zhang Y, et al. Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival. Oncogene. 2016;35:2441-52 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 3b
Lim T, Lee I, Kim J, Kang W. Synergistic Effect of Simvastatin Plus Radiation in Gastric Cancer and Colorectal Cancer: Implications of BIRC5 and Connective Tissue Growth Factor. Int J Radiat Oncol Biol Phys. 2015;93:316-25 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6
Uchiyama T, Kawabata H, Miura Y, Yoshioka S, Iwasa M, Yao H, et al. The role of growth differentiation factor 15 in the pathogenesis of primary myelofibrosis. Cancer Med. 2015;4:1558-72 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Steingruber M, Socher E, Hutterer C, Webel R, Bergbrede T, Lenac T, et al. The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain. Viruses. 2015;7:4582-601 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000
Meraviglia V, Azzimato V, Colussi C, Florio M, Binda A, Panariti A, et al. Acetylation mediates Cx43 reduction caused by electrical stimulation. J Mol Cell Cardiol. 2015;87:54-64 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Radoshevich L, Impens F, Ribet D, Quereda J, Nam Tham T, Nahori M, et al. ISG15 counteracts Listeria monocytogenes infection. elife. 2015;4: pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Zhen Y, Li W. Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33A(D251E) mutation. Autophagy. 2015;11:1608-22 pubmed 出版商
  • 免疫印迹; 人类; 图 9
Genin M, Clement F, Fattaccioli A, Raes M, Michiels C. M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide. BMC Cancer. 2015;15:577 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Ju X, Yan Y, Liu Q, Li N, Sheng M, Zhang L, et al. Neuraminidase of Influenza A Virus Binds Lysosome-Associated Membrane Proteins Directly and Induces Lysosome Rupture. J Virol. 2015;89:10347-58 pubmed 出版商
  • 免疫印迹; 小鼠
Lutzenberger M, Burwinkel M, Riemer C, Bode V, Baier M. Ablation of CCAAT/Enhancer-Binding Protein Delta (C/EBPD): Increased Plaque Burden in a Murine Alzheimer's Disease Model. PLoS ONE. 2015;10:e0134228 pubmed 出版商
  • 免疫印迹; 人类
Verrier E, Colpitts C, Bach C, Heydmann L, Weiss A, Renaud M, et al. A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses. Hepatology. 2016;63:35-48 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 2
Chen C, Tian F, Lu L, Wang Y, Xiao Z, Yu C, et al. Characterization of Cep85 - a new antagonist of Nek2A that is involved in the regulation of centrosome disjunction. J Cell Sci. 2015;128:3290-303 pubmed 出版商
  • 免疫印迹; 人类; 图 2d
Roncero A, López Nieva P, Cobos Fernández M, Villa Morales M, González Sánchez L, López Lorenzo J, et al. Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development. Leukemia. 2016;30:94-103 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Prasad S, Sajja R, Park J, Naik P, Kaisar M, Cucullo L. Impact of cigarette smoke extract and hyperglycemic conditions on blood-brain barrier endothelial cells. Fluids Barriers CNS. 2015;12:18 pubmed 出版商
  • 免疫印迹; 人类
He D, Chen H, Muramatsu H, Lasek A. Ethanol activates midkine and anaplastic lymphoma kinase signaling in neuroblastoma cells and in the brain. J Neurochem. 2015;135:508-21 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4,5
Gingras S, Earls L, Howell S, Smeyne R, Zakharenko S, Pelletier S. SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus. J Neurosci. 2015;35:10510-22 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Kreit M, Vertommen D, Gillet L, Michiels T. The Interferon-Inducible Mouse Apolipoprotein L9 and Prohibitins Cooperate to Restrict Theiler's Virus Replication. PLoS ONE. 2015;10:e0133190 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Yang Y, Liu Z, Wang F, Temviriyanukul P, Ma X, Tu Y, et al. FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress. Nucleic Acids Res. 2015;43:8325-39 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s8
Chiou S, Winters I, Wang J, Naranjo S, Dudgeon C, Tamburini F, et al. Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing. Genes Dev. 2015;29:1576-85 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 1
  • 免疫印迹; 人类; 1:5000; 图 9
Malik I, Stange I, Martius G, Cameron S, Rave Fränk M, Hess C, et al. Role of PECAM-1 in radiation-induced liver inflammation. J Cell Mol Med. 2015;19:2441-52 pubmed 出版商
  • 免疫印迹; 人类; 1:20,000; 图 3
Zhang F, Patel D, Colavita K, Rodionova I, Buckley B, Scott D, et al. Arginylation regulates purine nucleotide biosynthesis by enhancing the activity of phosphoribosyl pyrophosphate synthase. Nat Commun. 2015;6:7517 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s1g
Hobbs R, DePianto D, Jacob J, Han M, Chung B, Batazzi A, et al. Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes. Nat Genet. 2015;47:933-8 pubmed 出版商
  • 免疫印迹; 小鼠; 1:4000; 图 1
Wu H, Barik A, Lu Y, Shen C, Bowman A, Li L, et al. Slit2 as a β-catenin/Ctnnb1-dependent retrograde signal for presynaptic differentiation. elife. 2015;4: pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000
Maggiorani D, Dissard R, Belloy M, Saulnier Blache J, Casemayou A, Ducassé L, et al. Shear Stress-Induced Alteration of Epithelial Organization in Human Renal Tubular Cells. PLoS ONE. 2015;10:e0131416 pubmed 出版商
  • 免疫印迹; 小鼠; 1:7500; 图 2b
Yang F, Silber S, Leu N, Oates R, Marszalek J, Skaletsky H, et al. TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse. EMBO Mol Med. 2015;7:1198-210 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Sadaie M, Dillon C, Narita M, Young A, Cairney C, Godwin L, et al. Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition. Mol Biol Cell. 2015;26:2971-85 pubmed 出版商
  • 免疫印迹; 小鼠
Thatcher S, Zhang X, Woody S, Wang Y, Alsiraj Y, Charnigo R, et al. Exogenous 17-β estradiol administration blunts progression of established angiotensin II-induced abdominal aortic aneurysms in female ovariectomized mice. Biol Sex Differ. 2015;6:12 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Sive J, Basilico S, Hannah R, Kinston S, Calero Nieto F, Göttgens B. Genome-scale definition of the transcriptional programme associated with compromised PU.1 activity in acute myeloid leukaemia. Leukemia. 2016;30:14-23 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Huygens C, Liénart S, Dedobbeleer O, Stockis J, Gauthy E, Coulie P, et al. Lysosomal-associated Transmembrane Protein 4B (LAPTM4B) Decreases Transforming Growth Factor β1 (TGF-β1) Production in Human Regulatory T Cells. J Biol Chem. 2015;290:20105-16 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Zhang J, Gao Q, Zhou Y, Dier U, Hempel N, Hochwald S. Focal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis. Oncogene. 2016;35:1926-42 pubmed 出版商
  • 免疫印迹; 人类
Goichon A, Bertrand J, Chan P, Lecleire S, Coquard A, Cailleux A, et al. Enteral delivery of proteins enhances the expression of proteins involved in the cytoskeleton and protein biosynthesis in human duodenal mucosa. Am J Clin Nutr. 2015;102:359-67 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
Zhang J, Li L, Baldwin A, Friedman A, Paz Priel I. Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells. PLoS ONE. 2015;10:e0130441 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Pishas K, Adwal A, Neuhaus S, Clayer M, Farshid G, Staudacher A, et al. XI-006 induces potent p53-independent apoptosis in Ewing sarcoma. Sci Rep. 2015;5:11465 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Loveless T, Topacio B, Vashisht A, Galaang S, Ulrich K, Young B, et al. DNA Damage Regulates Translation through β-TRCP Targeting of CReP. PLoS Genet. 2015;11:e1005292 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Lu H, Xue Y, Xue Y, Yu G, Arias C, Lin J, et al. Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism. elife. 2015;4:e06535 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000
Liu G, Wang Z, Wang Z, Yang D, Liu Z, Wang L. Mitochondrial permeability transition and its regulatory components are implicated in apoptosis of primary cultures of rat proximal tubular cells exposed to lead. Arch Toxicol. 2016;90:1193-209 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1
Whalley H, Porter A, Diamantopoulou Z, White G, Castañeda Saucedo E, Malliri A. Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation. Nat Commun. 2015;6:7437 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Specks J, Lecona E, Lopez Contreras A, Fernandez Capetillo O. A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development. Mol Cell Biol. 2015;35:2910-7 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Preca B, Bajdak K, Mock K, Sundararajan V, Pfannstiel J, Maurer J, et al. A self-enforcing CD44s/ZEB1 feedback loop maintains EMT and stemness properties in cancer cells. Int J Cancer. 2015;137:2566-77 pubmed 出版商
  • 免疫印迹; 小鼠
Stermann A, Huebener N, Seidel D, Fest S, Eschenburg G, Stauder M, et al. Targeting of MYCN by means of DNA vaccination is effective against neuroblastoma in mice. Cancer Immunol Immunother. 2015;64:1215-27 pubmed 出版商
  • 免疫印迹; 小鼠
Schell C, Kretz O, Bregenzer A, Rogg M, Helmstädter M, Lisewski U, et al. Podocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress Response. PLoS ONE. 2015;10:e0129424 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Su Y, Chang Y, Lin W, Liang C, Lee J. An aberrant nuclear localization of E-cadherin is a potent inhibitor of Wnt/β-catenin-elicited promotion of the cancer stem cell phenotype. Oncogenesis. 2015;4:e157 pubmed 出版商
  • 免疫印迹; 大鼠; 1:10,000; 图 1
Bijata M, Wlodarczyk J, Figiel I. Dystroglycan controls dendritic morphogenesis of hippocampal neurons in vitro. Front Cell Neurosci. 2015;9:199 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Shen Y, Zeng L, Novosyadlyy R, Forest A, Zhu A, Korytko A, et al. A bi-functional antibody-receptor domain fusion protein simultaneously targeting IGF-IR and VEGF for degradation. MAbs. 2015;7:931-45 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Cerella C, Muller F, Gaigneaux A, Radogna F, Viry E, Chateauvieux S, et al. Early downregulation of Mcl-1 regulates apoptosis triggered by cardiac glycoside UNBS1450. Cell Death Dis. 2015;6:e1782 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Wagenknecht N, Reuter N, Scherer M, Reichel A, Müller R, Stamminger T. Contribution of the Major ND10 Proteins PML, hDaxx and Sp100 to the Regulation of Human Cytomegalovirus Latency and Lytic Replication in the Monocytic Cell Line THP-1. Viruses. 2015;7:2884-907 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 4
Dille S, Kleinschnitz E, Kontchou C, Nölke T, Häcker G. In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transport. Infect Immun. 2015;83:3268-80 pubmed 出版商
  • 免疫印迹; 人类; 图 2
von Einem B, Wahler A, Schips T, Serrano Pozo A, Proepper C, Boeckers T, et al. The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1). PLoS ONE. 2015;10:e0129047 pubmed 出版商
  • 免疫印迹; 人类
Holtzhausen A, Zhao F, Evans K, Tsutsui M, Orabona C, Tyler D, et al. Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy. Cancer Immunol Res. 2015;3:1082-95 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Subathra M, Korrapati M, Howell L, Arthur J, Shayman J, Schnellmann R, et al. Kidney glycosphingolipids are elevated early in diabetic nephropathy and mediate hypertrophy of mesangial cells. Am J Physiol Renal Physiol. 2015;309:F204-15 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 4
Castiglioni A, Corna G, Rigamonti E, Basso V, Vezzoli M, Monno A, et al. FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration. PLoS ONE. 2015;10:e0128094 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Tréhoux S, Lahdaoui F, Delpu Y, Renaud F, Leteurtre E, Torrisani J, et al. Micro-RNAs miR-29a and miR-330-5p function as tumor suppressors by targeting the MUC1 mucin in pancreatic cancer cells. Biochim Biophys Acta. 2015;1853:2392-403 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
Vinue A, Andrés Blasco I, Herrero Cervera A, Piqueras L, Andres V, Burks D, et al. Ink4/Arf locus restores glucose tolerance and insulin sensitivity by reducing hepatic steatosis and inflammation in mice with impaired IRS2-dependent signalling. Biochim Biophys Acta. 2015;1852:1729-42 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1b
Hayashi T, Wills S, Bussey K, Takimoto T. Identification of Influenza A Virus PB2 Residues Involved in Enhanced Polymerase Activity and Virus Growth in Mammalian Cells at Low Temperatures. J Virol. 2015;89:8042-9 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Yen C, Chiang W, Liu S, Lin C, Liao K, Lin C, et al. Impacts of autophagy-inducing ingredient of areca nut on tumor cells. PLoS ONE. 2015;10:e0128011 pubmed 出版商
  • 免疫印迹; 小鼠
Mulholland C, Smets M, Schmidtmann E, Leidescher S, Markaki Y, Hofweber M, et al. A modular open platform for systematic functional studies under physiological conditions. Nucleic Acids Res. 2015;43:e112 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Reigada D, Nieto Díaz M, Navarro Ruiz R, Caballero López M, Del Águila A, Muñoz Galdeano T, et al. Acute administration of ucf-101 ameliorates the locomotor impairments induced by a traumatic spinal cord injury. Neuroscience. 2015;300:404-17 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Suárez Causado A, Caballero Díaz D, Bertrán E, Roncero C, Addante A, García Álvaro M, et al. HGF/c-Met signaling promotes liver progenitor cell migration and invasion by an epithelial-mesenchymal transition-independent, phosphatidyl inositol-3 kinase-dependent pathway in an in vitro model. Biochim Biophys Acta. 2015;1853:2453-63 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Peng B, Wang J, Hu Y, Zhao H, Hou W, Zhao H, et al. Modulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damage. Nucleic Acids Res. 2015;43:5936-47 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000
Fischer S, Paul A, Wagner A, Mathias S, Geiss M, Schandock F, et al. miR-2861 as novel HDAC5 inhibitor in CHO cells enhances productivity while maintaining product quality. Biotechnol Bioeng. 2015;112:2142-53 pubmed 出版商
  • 免疫印迹; 人类
Moon J, Eo S, Lee J, Park S. Quercetin-induced autophagy flux enhances TRAIL-mediated tumor cell death. Oncol Rep. 2015;34:375-81 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Yufune S, Satoh Y, Takamatsu I, Ohta H, Kobayashi Y, Takaenoki Y, et al. Transient Blockade of ERK Phosphorylation in the Critical Period Causes Autistic Phenotypes as an Adult in Mice. Sci Rep. 2015;5:10252 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000; 图 1
  • 免疫印迹; 人类; 1:3000; 图 1
Robinson H, Deykin A, Bronovitsky E, Ovchinnikov R, Ustyugov A, Shelkovnikova T, et al. Early lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif. Amyotroph Lateral Scler Frontotemporal Degener. 2015;16:402-9 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000
Wang D, Kinoshita Y, Kinoshita C, Uo T, Sopher B, Cudaback E, et al. Loss of endophilin-B1 exacerbates Alzheimer's disease pathology. Brain. 2015;138:2005-19 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Wang Z, Ma B, Ji X, Deng Y, Zhang T, Zhang X, et al. MicroRNA-378-5p suppresses cell proliferation and induces apoptosis in colorectal cancer cells by targeting BRAF. Cancer Cell Int. 2015;15:40 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫印迹; 人类
Noss E, Watts G, Zocco D, Keller T, Whitman M, Blobel C, et al. Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism. Arthritis Res Ther. 2015;17:126 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Wang C, Nie Z, Zhou Z, Zhang H, Liu R, Wu J, et al. The interplay between TEAD4 and KLF5 promotes breast cancer partially through inhibiting the transcription of p27Kip1. Oncotarget. 2015;6:17685-97 pubmed
  • 免疫印迹; 人类; 1:1000
Adhikary G, Grun D, Balasubramanian S, Kerr C, Huang J, Eckert R. Survival of skin cancer stem cells requires the Ezh2 polycomb group protein. Carcinogenesis. 2015;36:800-10 pubmed 出版商
  • 免疫印迹; 人类
Bergeron D, Pal G, Beaulieu Y, Chabot B, Bachand F. Regulated Intron Retention and Nuclear Pre-mRNA Decay Contribute to PABPN1 Autoregulation. Mol Cell Biol. 2015;35:2503-17 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Tanas M, Ma S, Jadaan F, Ng C, Weigelt B, Reis Filho J, et al. Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein. Oncogene. 2016;35:929-38 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 s12
Pang B, de Jong J, Qiao X, Wessels L, Neefjes J. Chemical profiling of the genome with anti-cancer drugs defines target specificities. Nat Chem Biol. 2015;11:472-80 pubmed 出版商
  • 免疫印迹; 大鼠
Fujikawa Y, Tominaga K, Tanaka F, Tanigawa T, Watanabe T, Fujiwara Y, et al. Enteric glial cells are associated with stress-induced colonic hyper-contraction in maternally separated rats. Neurogastroenterol Motil. 2015;27:1010-23 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000
Son Y, Heo K, Bae M, Lee C, Cho W, Kim S, et al. Injury to the blood-testis barrier after low-dose-rate chronic radiation exposure in mice. Radiat Prot Dosimetry. 2015;167:316-20 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Barrett K, Fang H, Cukovic D, Dombkowski A, Kocarek T, Runge Morris M. Upregulation of UGT2B4 Expression by 3'-Phosphoadenosine-5'-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid Conjugation. Drug Metab Dispos. 2015;43:1061-70 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Shi Y, Tan S, Ng S, Zhou J, Yang N, Koo G, et al. Critical role of CAV1/caveolin-1 in cell stress responses in human breast cancer cells via modulation of lysosomal function and autophagy. Autophagy. 2015;11:769-84 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Milenkovic A, Brandl C, Milenkovic V, Jendryke T, Sirianant L, Wanitchakool P, et al. Bestrophin 1 is indispensable for volume regulation in human retinal pigment epithelium cells. Proc Natl Acad Sci U S A. 2015;112:E2630-9 pubmed 出版商
  • 免疫印迹; 人类
Fisher M, Keillor J, Xu W, Eckert R, Kerr C. Transglutaminase Is Required for Epidermal Squamous Cell Carcinoma Stem Cell Survival. Mol Cancer Res. 2015;13:1083-94 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Isogai T, van der Kammen R, Innocenti M. SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton. Sci Rep. 2015;5:9802 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000
Cardoso F, Herz J, Fernandes A, Rocha J, Sepodes B, Brito M, et al. Systemic inflammation in early neonatal mice induces transient and lasting neurodegenerative effects. J Neuroinflammation. 2015;12:82 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Hsu P, Liu X, Zhang J, Wang H, Ye J, Shi Y. Cardiolipin remodeling by TAZ/tafazzin is selectively required for the initiation of mitophagy. Autophagy. 2015;11:643-52 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3
Bhushan S, Tchatalbachev S, Lu Y, Fröhlich S, Fijak M, Vijayan V, et al. Differential activation of inflammatory pathways in testicular macrophages provides a rationale for their subdued inflammatory capacity. J Immunol. 2015;194:5455-64 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b
Watanabe M, Takahashi H, Saeki Y, Ozaki T, Itoh S, Suzuki M, et al. The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARγ. elife. 2015;4:e05615 pubmed 出版商
  • 免疫印迹; 人类
Ezzati P, Komher K, Severini G, Coombs K. Comparative proteomic analyses demonstrate enhanced interferon and STAT-1 activation in reovirus T3D-infected HeLa cells. Front Cell Infect Microbiol. 2015;5:30 pubmed 出版商
  • 免疫印迹; 人类
Willy J, Young S, Stevens J, Masuoka H, Wek R. CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis. Mol Biol Cell. 2015;26:2190-204 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:2500
Huang S, Sung C, Chen W, Chen C, Feng C, Yang S, et al. Involvement of phosphatase and tensin homolog deleted from chromosome 10 in rodent model of neuropathic pain. J Neuroinflammation. 2015;12:59 pubmed 出版商
  • 免疫印迹; 人类
Zhao H, Agazie Y. Inhibition of SHP2 in basal-like and triple-negative breast cells induces basal-to-luminal transition, hormone dependency, and sensitivity to anti-hormone treatment. BMC Cancer. 2015;15:109 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Mues M, Cheshenko N, Wilson D, Gunther Cummins L, Herold B. Dynasore disrupts trafficking of herpes simplex virus proteins. J Virol. 2015;89:6673-84 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 3
Meidhof S, Brabletz S, Lehmann W, Preca B, Mock K, Ruh M, et al. ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat. EMBO Mol Med. 2015;7:831-47 pubmed 出版商
  • 免疫印迹; 人类
Corbel C, Zhang B, Le Parc A, Baratte B, Colas P, Couturier C, et al. Tamoxifen inhibits CDK5 kinase activity by interacting with p35/p25 and modulates the pattern of tau phosphorylation. Chem Biol. 2015;22:472-482 pubmed 出版商
  • 其他; 人类; 图 2
Jørgensen M, Bæk R, Varming K. Potentials and capabilities of the Extracellular Vesicle (EV) Array. J Extracell Vesicles. 2015;4:26048 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 1d
Lund K, Dembinski J, Solberg N, Urbanucci A, Mills I, Krauss S. Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment. PLoS ONE. 2015;10:e0123684 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Wang X, D Arcy P, Caulfield T, Paulus A, Chitta K, Mohanty C, et al. Synthesis and evaluation of derivatives of the proteasome deubiquitinase inhibitor b-AP15. Chem Biol Drug Des. 2015;86:1036-48 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 6
Ecker J, Oehme I, Mazitschek R, Korshunov A, Kool M, Hielscher T, et al. Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma. Acta Neuropathol Commun. 2015;3:22 pubmed 出版商
  • 免疫印迹; 人类
Saha K, Eckert R. Methylosome Protein 50 and PKC?/p38? Protein Signaling Control Keratinocyte Proliferation via Opposing Effects on p21Cip1 Gene Expression. J Biol Chem. 2015;290:13521-30 pubmed 出版商
  • 免疫印迹; 小鼠
Kim T, Lawson M. GnRH Regulates Gonadotropin Gene Expression Through NADPH/Dual Oxidase-Derived Reactive Oxygen Species. Endocrinology. 2015;156:2185-99 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Li Y, Drabsch Y, Pujuguet P, Ren J, van Laar T, Zhang L, et al. Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models. Breast Cancer Res. 2015;17:28 pubmed 出版商
  • 免疫印迹; 小鼠
Majumder A, Syed K, Joseph S, Scambler P, Dutta D. Histone Chaperone HIRA in Regulation of Transcription Factor RUNX1. J Biol Chem. 2015;290:13053-63 pubmed 出版商
  • 免疫组化; 大鼠
Fausther M, Goree J, Lavoie Ã, Graham A, Sévigny J, Dranoff J. Establishment and characterization of rat portal myofibroblast cell lines. PLoS ONE. 2015;10:e0121161 pubmed 出版商
  • 免疫印迹; 人类; 图 7e
Bol G, Vesuna F, Xie M, Zeng J, Aziz K, Gandhi N, et al. Targeting DDX3 with a small molecule inhibitor for lung cancer therapy. EMBO Mol Med. 2015;7:648-69 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Ngo J, Matsuyama M, Kim C, Poventud Fuentes I, Bates A, Siedlak S, et al. Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases. Cell Death Dis. 2015;6:e1706 pubmed 出版商
  • 免疫印迹; 人类; 1:300-500
Sajja R, Green K, Cucullo L. Altered Nrf2 signaling mediates hypoglycemia-induced blood-brain barrier endothelial dysfunction in vitro. PLoS ONE. 2015;10:e0122358 pubmed 出版商
  • 免疫印迹; 小鼠
Yan J, Zapata J, PAUZA C, Salvato M. Modulation of SIV and HIV DNA vaccine immunity by Fas-FasL signaling. Viruses. 2015;7:1429-53 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Kirschner K, Samarajiwa S, Cairns J, Menon S, Perez Mancera P, Tomimatsu K, et al. Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53. PLoS Genet. 2015;11:e1005053 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Kuo R, Lin Y, Wang R, Hsu C, Chiu Y, Huang H, et al. Proteomics analysis of EV71-infected cells reveals the involvement of host protein NEDD4L in EV71 replication. J Proteome Res. 2015;14:1818-30 pubmed 出版商
  • 免疫印迹; 人类; 图 3
CURTIS J, Luo Y, Zenner H, Cuchet Lourenço D, Wu C, Lo K, et al. Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration. Nat Genet. 2015;47:523-527 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1,2,3,4,5,6,7
Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, et al. Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy. EMBO J. 2015;34:1214-30 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Hodgson A, Wier E, Fu K, Sun X, Yu H, Zheng W, et al. Metalloprotease NleC suppresses host NF-κB/inflammatory responses by cleaving p65 and interfering with the p65/RPS3 interaction. PLoS Pathog. 2015;11:e1004705 pubmed 出版商
  • 免疫印迹; 人类
Howlin J, Cirenajwis H, Lettiero B, Staaf J, Lauss M, Saal L, et al. Loss of CITED1, an MITF regulator, drives a phenotype switch in vitro and can predict clinical outcome in primary melanoma tumours. Peerj. 2015;3:e788 pubmed 出版商
  • 免疫印迹; 人类
Münzberg C, Höhn K, Krndija D, Maaß U, Bartsch D, Slater E, et al. IGF-1 drives chromogranin A secretion via activation of Arf1 in human neuroendocrine tumour cells. J Cell Mol Med. 2015;19:948-59 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2C
Pone E, Lam T, Lou Z, Wang R, Chen Y, Liu D, et al. B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses. J Immunol. 2015;194:3065-78 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000
Rogler A, Kendziorra E, Giedl J, Stoehr C, Taubert H, Goebell P, et al. Functional analyses and prognostic significance of SFRP1 expression in bladder cancer. J Cancer Res Clin Oncol. 2015;141:1779-90 pubmed 出版商
  • 免疫印迹; 人类; 1:4000; 图 2
Medina D, Di Paola S, Peluso I, Armani A, De Stefani D, Venditti R, et al. Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB. Nat Cell Biol. 2015;17:288-99 pubmed
  • 免疫印迹; 人类; 图 2
Cruse G, Beaven M, Music S, Bradding P, Gilfillan A, Metcalfe D. The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling. Mol Biol Cell. 2015;26:1711-27 pubmed 出版商
  • 免疫印迹; 人类; 1:3000
Koganti S, Clark C, Zhi J, Li X, Chen E, Chakrabortty S, et al. Cellular STAT3 functions via PCBP2 to restrain Epstein-Barr Virus lytic activation in B lymphocytes. J Virol. 2015;89:5002-11 pubmed 出版商
  • 免疫印迹; 人类; 1:40,000; 图 1
Susanto J, Colvin E, Pinese M, Chang D, Pajic M, Mawson A, et al. The epigenetic agents suberoylanilide hydroxamic acid and 5‑AZA‑2' deoxycytidine decrease cell proliferation, induce cell death and delay the growth of MiaPaCa2 pancreatic cancer cells in vivo. Int J Oncol. 2015;46:2223-30 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Nakagawa Y, Sedukhina A, Okamoto N, Nagasawa S, Suzuki N, Ohta T, et al. NF-κB signaling mediates acquired resistance after PARP inhibition. Oncotarget. 2015;6:3825-39 pubmed
  • 免疫印迹; 人类; 1:10,000; 图 1
Bitler B, Aird K, Garipov A, Li H, Amatangelo M, Kossenkov A, et al. Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers. Nat Med. 2015;21:231-8 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Nagasawa S, Sedukhina A, Nakagawa Y, Maeda I, Kubota M, Ohnuma S, et al. LSD1 overexpression is associated with poor prognosis in basal-like breast cancer, and sensitivity to PARP inhibition. PLoS ONE. 2015;10:e0118002 pubmed 出版商
  • 免疫印迹; 人类
Nakajima T, Kitagawa K, Ohhata T, Sakai S, Uchida C, Shibata K, et al. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2. J Biol Chem. 2015;290:10368-81 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Gotink K, Rovithi M, de Haas R, Honeywell R, Dekker H, Poel D, et al. Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib. Cell Oncol (Dordr). 2015;38:119-29 pubmed 出版商
  • 免疫印迹; 小鼠; 1:20,000; 图 6
Porquet D, Andrés Benito P, Griñán Ferré C, Camins A, Ferrer I, Canudas A, et al. Amyloid and tau pathology of familial Alzheimer's disease APP/PS1 mouse model in a senescence phenotype background (SAMP8). Age (Dordr). 2015;37:9747 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Suganya R, Chakraborty A, Miriyala S, Hazra T, Izumi T. Suppression of oxidative phosphorylation in mouse embryonic fibroblast cells deficient in apurinic/apyrimidinic endonuclease. DNA Repair (Amst). 2015;27:40-8 pubmed 出版商
  • 免疫印迹; 小鼠
Kathania M, Zeng M, Yadav V, Moghaddam S, Yang B, Venuprasad K. Ndfip1 regulates itch ligase activity and airway inflammation via UbcH7. J Immunol. 2015;194:2160-7 pubmed 出版商
  • 免疫印迹; 人类
Niu Z, Liu H, Zhou M, Wang H, Liu Y, Li X, et al. Knockdown of c-Myc inhibits cell proliferation by negatively regulating the Cdk/Rb/E2F pathway in nasopharyngeal carcinoma cells. Acta Biochim Biophys Sin (Shanghai). 2015;47:183-91 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Hole S, Pedersen A, Hansen S, Lundqvist J, Yde C, Lykkesfeldt A. New cell culture model for aromatase inhibitor-resistant breast cancer shows sensitivity to fulvestrant treatment and cross-resistance between letrozole and exemestane. Int J Oncol. 2015;46:1481-90 pubmed 出版商
  • 免疫印迹; 小鼠
Cai K, Wang Y, Smith E, Smedberg J, Yang D, Yang W, et al. Global deletion of Trp53 reverts ovarian tumor phenotype of the germ cell-deficient white spotting variant (Wv) mice. Neoplasia. 2015;17:89-100 pubmed 出版商
  • 免疫印迹; 人类; 1:4000; 图 7
Warnier M, Roudbaraki M, Derouiche S, Delcourt P, Bokhobza A, Prevarskaya N, et al. CACNA2D2 promotes tumorigenesis by stimulating cell proliferation and angiogenesis. Oncogene. 2015;34:5383-94 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Han M, Woo S, Min K, Kim S, Park J, Kim D, et al. 6-Shogaol enhances renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated cytochrome c release and down-regulation of c-FLIP(L) expression. Chem Biol Interact. 2015;228:69-78 pubmed 出版商
  • 免疫印迹; 大鼠; 图 5
Sadegh M, Ekman M, Krawczyk K, Svensson D, Göransson O, Dahan D, et al. Detrusor induction of miR-132/212 following bladder outlet obstruction: association with MeCP2 repression and cell viability. PLoS ONE. 2015;10:e0116784 pubmed 出版商
  • 免疫印迹; 人类; 1:50,000
Olsen R, Mary Sinclair M, Yin Z, Freeman K. Antagonizing Bcl-2 family members sensitizes neuroblastoma and Ewing's sarcoma to an inhibitor of glutamine metabolism. PLoS ONE. 2015;10:e0116998 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 3b
  • 免疫印迹; 小鼠; 1:5000; 图 2c
Wang L, Liu R, Ye P, Wong C, Chen G, Zhou P, et al. Intracellular CD24 disrupts the ARF-NPM interaction and enables mutational and viral oncogene-mediated p53 inactivation. Nat Commun. 2015;6:5909 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
  • 免疫印迹; 大鼠; 图 6
Yuan Y, Rangarajan P, Kan E, Wu Y, Wu C, Ling E. Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia. J Neuroinflammation. 2015;12:11 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3d
Keembiyehetty C, Love D, Harwood K, Gavrilova O, Comly M, Hanover J. Conditional knock-out reveals a requirement for O-linked N-Acetylglucosaminase (O-GlcNAcase) in metabolic homeostasis. J Biol Chem. 2015;290:7097-113 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
Tanaka T, Kajiwara T, Torigoe T, Okamoto Y, Sato N, Tamura Y. Cancer-associated oxidoreductase ERO1-α drives the production of tumor-promoting myeloid-derived suppressor cells via oxidative protein folding. J Immunol. 2015;194:2004-10 pubmed 出版商
  • 免疫细胞化学; 人类; 1:40,000; 图 3
  • 免疫印迹; 人类; 1:40,000; 图 3
Stolz A, Ertych N, Bastians H. A phenotypic screen identifies microtubule plus end assembly regulators that can function in mitotic spindle orientation. Cell Cycle. 2015;14:827-37 pubmed 出版商
  • 酶联免疫吸附测定; 大鼠
  • 免疫印迹; 大鼠; 1:1000
Maurya S, Mishra J, Abbas S, Bandyopadhyay S. Cypermethrin Stimulates GSK3β-Dependent Aβ and p-tau Proteins and Cognitive Loss in Young Rats: Reduced HB-EGF Signaling and Downstream Neuroinflammation as Critical Regulators. Mol Neurobiol. 2016;53:968-82 pubmed 出版商
  • 免疫印迹; 小鼠; 1:6000; 图 3
Chang K, Nayak R, Roy S, Perumbeti A, Wellendorf A, Bezold K, et al. Vasculopathy-associated hyperangiotensinemia mobilizes haematopoietic stem cells/progenitors through endothelial ATâ‚‚R and cytoskeletal dysregulation. Nat Commun. 2015;6:5914 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 6
  • 免疫印迹; 人类; 1:5000; 图 s5
Besschetnova T, Ichimura T, Katebi N, St Croix B, Bonventre J, Olsen B. Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis. Matrix Biol. 2015;42:56-73 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Valianou M, Cox A, Pichette B, Hartley S, Paladhi U, Astrinidis A. Pharmacological inhibition of Polo-like kinase 1 (PLK1) by BI-2536 decreases the viability and survival of hamartin and tuberin deficient cells via induction of apoptosis and attenuation of autophagy. Cell Cycle. 2015;14:399-407 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7
Shrestha S, Yang K, Guy C, Vogel P, Neale G, Chi H. Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. Nat Immunol. 2015;16:178-87 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 4
Harr J, Luperchio T, Wong X, Cohen E, Wheelan S, Reddy K. Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins. J Cell Biol. 2015;208:33-52 pubmed 出版商
  • 免疫印迹; zebra finch; 1:20,000
Mendoza E, Tokarev K, Düring D, Retamosa E, Weiss M, Arpenik N, et al. Differential coexpression of FoxP1, FoxP2, and FoxP4 in the Zebra Finch (Taeniopygia guttata) song system. J Comp Neurol. 2015;523:1318-40 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1d
Krysiak K, Tibbitts J, Shao J, Liu T, Ndonwi M, Walter M. Reduced levels of Hspa9 attenuate Stat5 activation in mouse B cells. Exp Hematol. 2015;43:319-30.e10 pubmed 出版商
  • 免疫印迹; 人类
Hatano R, Ohnuma K, Otsuka H, Komiya E, Taki I, Iwata S, et al. CD26-mediated induction of EGR2 and IL-10 as potential regulatory mechanism for CD26 costimulatory pathway. J Immunol. 2015;194:960-72 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
  • 免疫印迹; 小鼠
Ni H, Bhakta A, Wang S, Li Z, Manley S, Huang H, et al. Role of hypoxia inducing factor-1β in alcohol-induced autophagy, steatosis and liver injury in mice. PLoS ONE. 2014;9:e115849 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s3
Yang Y, Otte A, Hass R. Human mesenchymal stroma/stem cells exchange membrane proteins and alter functionality during interaction with different tumor cell lines. Stem Cells Dev. 2015;24:1205-22 pubmed 出版商
  • 免疫印迹; 大鼠; 1:10,000
Tsai M, Chu C, Wei T, Chiu M, Chang C, Wei I, et al. CD200 in growing rat lungs: developmental expression and control by dexamethasone. Cell Tissue Res. 2015;359:729-42 pubmed 出版商
  • 免疫印迹; 人类
Shao C, Ahmad N, Hodges K, Kuang S, Ratliff T, Liu X. Inhibition of polo-like kinase 1 (Plk1) enhances the antineoplastic activity of metformin in prostate cancer. J Biol Chem. 2015;290:2024-33 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 6
Qiao X, Roth I, Féraille E, Hasler U. Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion. Cell Cycle. 2014;13:3059-75 pubmed 出版商
  • 免疫沉淀; 人类; 图 3
Jirawatnotai S, Sharma S, Michowski W, Suktitipat B, Geng Y, Quackenbush J, et al. The cyclin D1-CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis. Cell Cycle. 2014;13:2889-900 pubmed 出版商
  • 免疫印迹; 人类
Selmi A, de Saint Jean M, Jallas A, Garin E, Hogarty M, Bénard J, et al. TWIST1 is a direct transcriptional target of MYCN and MYC in neuroblastoma. Cancer Lett. 2015;357:412-8 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Diesenberg K, Beerbaum M, Fink U, Schmieder P, Krauss M. SEPT9 negatively regulates ubiquitin-dependent downregulation of EGFR. J Cell Sci. 2015;128:397-407 pubmed 出版商
  • 免疫印迹; 大鼠
Yang D, Sun Y, Bhaumik S, Li Y, Baumann J, Lin X, et al. Blocking lymphocyte trafficking with FTY720 prevents inflammation-sensitized hypoxic-ischemic brain injury in newborns. J Neurosci. 2014;34:16467-81 pubmed 出版商
  • 免疫印迹; Garra rufa
Oksala N, Ekmekçi F, Ozsoy E, Kirankaya S, Kokkola T, Emecen G, et al. Natural thermal adaptation increases heat shock protein levels and decreases oxidative stress. Redox Biol. 2014;3:25-8 pubmed 出版商
  • 免疫印迹; 人类
Kuo P, Huang C, Lee C, Chang H, Hsieh S, Chung Y, et al. BCAS2 promotes prostate cancer cells proliferation by enhancing AR mRNA transcription and protein stability. Br J Cancer. 2015;112:391-402 pubmed 出版商
  • 免疫印迹; 人类; 1:70,000; 图 2d
Ã…gren M, Schnabel R, Christensen L, Mirastschijski U. Tumor necrosis factor-α-accelerated degradation of type I collagen in human skin is associated with elevated matrix metalloproteinase (MMP)-1 and MMP-3 ex vivo. Eur J Cell Biol. 2015;94:12-21 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000
Yokoi F, Dang M, Liu J, Gandre J, Kwon K, Yuen R, et al. Decreased dopamine receptor 1 activity and impaired motor-skill transfer in Dyt1 ΔGAG heterozygous knock-in mice. Behav Brain Res. 2015;279:202-10 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Zhao S, Ge X, Wang X, Liu A, Guo X, Zhou L, et al. The DEAD-box RNA helicase 5 positively regulates the replication of porcine reproductive and respiratory syndrome virus by interacting with viral Nsp9 in vitro. Virus Res. 2015;195:217-24 pubmed 出版商
  • 免疫印迹; 人类
Kim H, Jung G. Reactive oxygen species increase HEPN1 expression via activation of the XBP1 transcription factor. FEBS Lett. 2014;588:4413-21 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 2
Ma B, Chen Y, Chen L, Cheng H, Mu C, Li J, et al. Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase. Nat Cell Biol. 2015;17:95-103 pubmed 出版商
  • 免疫印迹; 小鼠
Zanotti K, Maul R, Castiblanco D, Yang W, Choi Y, Fox J, et al. ATAD5 deficiency decreases B cell division and Igh recombination. J Immunol. 2015;194:35-42 pubmed 出版商
  • 免疫印迹; 大鼠
Krawczyk P, Twarog E, Kurowska E, Klopotowska D, Matuszyk J. Establishment of a cellular model to study TrkC-dependent neuritogenesis. In Vitro Cell Dev Biol Anim. 2015;51:241-8 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Choi C, Kim J, Wee S, Lee J, Nam D, Kim C, et al. Expression of nuclear factor erythroid 2 protein in malignant cutaneous tumors. Arch Plast Surg. 2014;41:654-60 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Chruscicka B, Burnat G, Branski P, Chorobik P, Lenda T, Marciniak M, et al. Tetracycline-based system for controlled inducible expression of group III metabotropic glutamate receptors. J Biomol Screen. 2015;20:350-8 pubmed 出版商
  • 免疫印迹; 人类; 1:30,000
Shimamoto A, Kagawa H, Zensho K, Sera Y, Kazuki Y, Osaki M, et al. Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture. PLoS ONE. 2014;9:e112900 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000
Martínez Vega R, Garrido F, Partearroyo T, Cediel R, Zeisel S, Martínez Álvarez C, et al. Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism. FASEB J. 2015;29:418-32 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Dejos C, Voisin P, Bernard M, Régnacq M, Bergès T. Canthin-6-one displays antiproliferative activity and causes accumulation of cancer cells in the G2/M phase. J Nat Prod. 2014;77:2481-7 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Pérez Alvarez M, Mateos L, Alonso A, Wandosell F. Estradiol and Progesterone Administration After pMCAO Stimulates the Neurological Recovery and Reduces the Detrimental Effect of Ischemia Mainly in Hippocampus. Mol Neurobiol. 2015;52:1690-1703 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Qin J, Rajaratnam R, Feng L, Salami J, Barber Rotenberg J, Domsic J, et al. Development of organometallic S6K1 inhibitors. J Med Chem. 2015;58:305-14 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Phillips Krawczak C, Singla A, Starokadomskyy P, Deng Z, Osborne D, Li H, et al. COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A. Mol Biol Cell. 2015;26:91-103 pubmed 出版商
  • 免疫印迹; 人类
Srinivasan S, Romagnoli M, Bohm A, Sonenshein G. N-glycosylation regulates ADAM8 processing and activation. J Biol Chem. 2014;289:33676-88 pubmed 出版商
  • 免疫印迹; 人类
Lambert J, Whitson R, Iczkowski K, La Rosa F, Smith M, Wilson R, et al. Reduced expression of GDF-15 is associated with atrophic inflammatory lesions of the prostate. Prostate. 2015;75:255-65 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Bowton E, Saunders C, Reddy I, Campbell N, Hamilton P, Henry L, et al. SLC6A3 coding variant Ala559Val found in two autism probands alters dopamine transporter function and trafficking. Transl Psychiatry. 2014;4:e464 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Goren I, Pfeilschifter J, Frank S. Uptake of neutrophil-derived Ym1 protein distinguishes wound macrophages in the absence of interleukin-4 signaling in murine wound healing. Am J Pathol. 2014;184:3249-61 pubmed 出版商
  • 免疫印迹; 人类
Yang N, Tan S, Ng S, Shi Y, Zhou J, Tan K, et al. Artesunate induces cell death in human cancer cells via enhancing lysosomal function and lysosomal degradation of ferritin. J Biol Chem. 2014;289:33425-41 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000
Laporta J, Keil K, Vezina C, Hernandez L. Peripheral serotonin regulates maternal calcium trafficking in mammary epithelial cells during lactation in mice. PLoS ONE. 2014;9:e110190 pubmed 出版商
  • 免疫细胞化学; 大鼠
Ashok A, Rai N, Tripathi S, Bandyopadhyay S. Exposure to As-, Cd-, and Pb-mixture induces Aβ, amyloidogenic APP processing and cognitive impairments via oxidative stress-dependent neuroinflammation in young rats. Toxicol Sci. 2015;143:64-80 pubmed 出版商
  • 免疫印迹; 人类; 图 4
  • 免疫印迹; 小鼠; 图 5
Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, et al. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex. J Exp Med. 2014;211:2249-63 pubmed 出版商
  • 免疫印迹; 人类; 1:4000
Saloura V, Cho H, Kiyotani K, Alachkar H, Zuo Z, Nakakido M, et al. WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck. Mol Cancer Res. 2015;13:293-304 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1
Schmidt J, Dalby A, Cech T. Identification of human TERT elements necessary for telomerase recruitment to telomeres. elife. 2014;3: pubmed 出版商
  • 免疫印迹; 小鼠
Morioka T, Sakabe M, Ioka T, Iguchi T, Mizuta K, Hattammaru M, et al. An important role of endothelial hairy-related transcription factors in mouse vascular development. Genesis. 2014;52:897-906 pubmed 出版商
  • 免疫印迹; 人类; 1:20,000
Lupino E, Ramondetti C, Buccinnà B, Piccinini M. Exposure of neuroblastoma cell lines to imatinib results in the upregulation of the CDK inhibitor p27(KIP1) as a consequence of c-Abl inhibition. Biochem Pharmacol. 2014;92:235-50 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Ahn J, Ruiz P, Barber G. Intrinsic self-DNA triggers inflammatory disease dependent on STING. J Immunol. 2014;193:4634-42 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Iannetti A, Ledoux A, Tudhope S, Sellier H, Zhao B, Mowla S, et al. Regulation of p53 and Rb links the alternative NF-κB pathway to EZH2 expression and cell senescence. PLoS Genet. 2014;10:e1004642 pubmed 出版商
  • 免疫印迹; 人类
Ishii J, Sato H, Yazawa T, Shishido Hara Y, Hiramatsu C, Nakatani Y, et al. Class III/IV POU transcription factors expressed in small cell lung cancer cells are involved in proneural/neuroendocrine differentiation. Pathol Int. 2014;64:415-22 pubmed 出版商
  • 免疫印迹; 人类; 图 5
  • 免疫印迹; 小鼠; 图 3
Chang Y, Huang Y. Arsenite-activated JNK signaling enhances CPEB4-Vinexin interaction to facilitate stress granule assembly and cell survival. PLoS ONE. 2014;9:e107961 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500
  • 免疫印迹; 小鼠; 1:5000
Perreten Lambert H, Zenger M, Azarias G, Chatton J, Magistretti P, Lengacher S. Control of mitochondrial pH by uncoupling protein 4 in astrocytes promotes neuronal survival. J Biol Chem. 2014;289:31014-28 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b
Bertin S, Lozano Ruiz B, Bachiller V, García Martínez I, Herdman S, Zapater P, et al. Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice. Mucosal Immunol. 2015;8:505-15 pubmed 出版商
  • 免疫印迹; 大鼠; 1:2000
Jebelli J, Hooper C, Pocock J. Microglial p53 activation is detrimental to neuronal synapses during activation-induced inflammation: Implications for neurodegeneration. Neurosci Lett. 2014;583:92-7 pubmed 出版商
  • 免疫印迹; 人类
Kelsey L, Katoch P, Ray A, Mitra S, Chakraborty S, Lin M, et al. Vitamin D3 regulates the formation and degradation of gap junctions in androgen-responsive human prostate cancer cells. PLoS ONE. 2014;9:e106437 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫印迹; 小鼠
Yamasaki T, Suzuki A, Hasebe R, Horiuchi M. Comparison of the anti-prion mechanism of four different anti-prion compounds, anti-PrP monoclonal antibody 44B1, pentosan polysulfate, chlorpromazine, and U18666A, in prion-infected mouse neuroblastoma cells. PLoS ONE. 2014;9:e106516 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 2
Gruol D, Vo K, Bray J. Increased astrocyte expression of IL-6 or CCL2 in transgenic mice alters levels of hippocampal and cerebellar proteins. Front Cell Neurosci. 2014;8:234 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000
Wang H, Yuan Y, Zhang Z, Yan H, Feng Y, Li W. Dysbindin-1C is required for the survival of hilar mossy cells and the maturation of adult newborn neurons in dentate gyrus. J Biol Chem. 2014;289:29060-72 pubmed 出版商
  • 免疫印迹; 人类
Peng M, Emmadi R, Wang Z, Wiley E, Gann P, Khan S, et al. PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors. Oncotarget. 2014;5:6038-48 pubmed
  • 免疫印迹; 大鼠
Xiong R, Siegel D, Ross D. Quinone-induced protein handling changes: implications for major protein handling systems in quinone-mediated toxicity. Toxicol Appl Pharmacol. 2014;280:285-95 pubmed 出版商
  • 免疫印迹; 大鼠; 1:10,000
Yang L, Kan E, Lu J, Wu C, Ling E. Expression of 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) and its roles in activated microglia in vivo and in vitro. J Neuroinflammation. 2014;11:148 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Ito S, Ueda T, Ueno A, Nakagawa H, Taniguchi H, Hongo F, et al. Paired box 2 upregulates androgen receptor gene expression in androgen-independent prostate cancer. FEBS J. 2014;281:4506-18 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000; 图 4
Chau M, Deveau T, Song M, Gu X, Chen D, Wei L. iPSC Transplantation increases regeneration and functional recovery after ischemic stroke in neonatal rats. Stem Cells. 2014;32:3075-87 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 7
Wu A, Yang M, Dalvi P, Turinsky A, Wang W, Butcher D, et al. Role of STAT5 and epigenetics in lactation-associated upregulation of multidrug transporter ABCG2 in the mammary gland. Am J Physiol Endocrinol Metab. 2014;307:E596-610 pubmed 出版商
  • 免疫印迹; 人类
Bae J, Lee S, Park C, Lee Y, Chun T. Trafficking of LAG-3 to the surface on activated T cells via its cytoplasmic domain and protein kinase C signaling. J Immunol. 2014;193:3101-12 pubmed 出版商
  • 免疫印迹; 小鼠
Baek J, Kim J, Cheon Y, Park S, Ahn S, Yoon K, et al. Aconitum pseudo-laeve var. erectum inhibits receptor activator of nuclear factor kappa-B ligand-induced osteoclastogenesis via the c-Fos/nuclear factor of activated T-cells, cytoplasmic 1 signaling pathway and prevents lipopolysaccharide-induced bone. Molecules. 2014;19:11628-44 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Matsuda M, Suzuki R, Kataoka C, Watashi K, Aizaki H, Kato N, et al. Alternative endocytosis pathway for productive entry of hepatitis C virus. J Gen Virol. 2014;95:2658-67 pubmed 出版商
  • 免疫印迹; 小鼠
Viceconte N, McKenna T, Eriksson M. Low levels of the reverse transactivator fail to induce target transgene expression in vascular smooth muscle cells. PLoS ONE. 2014;9:e104098 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Vassilopoulos A, Tominaga Y, Kim H, Lahusen T, Li B, Yu H, et al. WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis. Oncogene. 2015;34:3023-35 pubmed 出版商
  • 免疫印迹; 小鼠
Bartuzi P, Wijshake T, Dekker D, Fedoseienko A, Kloosterhuis N, Youssef S, et al. A cell-type-specific role for murine Commd1 in liver inflammation. Biochim Biophys Acta. 2014;1842:2257-65 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000; 图 3
Rutkai I, Katakam P, Dutta S, Busija D. Sustained mitochondrial functioning in cerebral arteries after transient ischemic stress in the rat: a potential target for therapies. Am J Physiol Heart Circ Physiol. 2014;307:H958-66 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500,000
Dalmases M, Torres M, Márquez Kisinousky L, Almendros I, Planas A, Embid C, et al. Brain tissue hypoxia and oxidative stress induced by obstructive apneas is different in young and aged rats. Sleep. 2014;37:1249-56 pubmed 出版商
  • 免疫印迹; 小鼠; 1:30,000
Requejo Aguilar R, Lopez Fabuel I, Fernandez E, Martins L, Almeida A, Bolanos J. PINK1 deficiency sustains cell proliferation by reprogramming glucose metabolism through HIF1. Nat Commun. 2014;5:4514 pubmed 出版商
  • 免疫印迹; 大鼠; 1:20,000
Shibeeb O, Wood J, Casson R, Chidlow G. Effects of a conventional photocoagulator and a 3-ns pulse laser on preconditioning responses and retinal ganglion cell survival after optic nerve crush. Exp Eye Res. 2014;127:77-90 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Tan G, Chan E, Molnar A, Sarkar R, Alexieva D, Isa I, et al. 5' isomiR variation is of functional and evolutionary importance. Nucleic Acids Res. 2014;42:9424-35 pubmed 出版商
  • 免疫印迹; 大鼠
Banoujaafar H, Van Hoecke J, Mossiat C, Marie C. Brain BDNF levels elevation induced by physical training is reduced after unilateral common carotid artery occlusion in rats. J Cereb Blood Flow Metab. 2014;34:1681-7 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000
Boros J, Arnoult N, Stroobant V, Collet J, Decottignies A. Polycomb repressive complex 2 and H3K27me3 cooperate with H3K9 methylation to maintain heterochromatin protein 1? at chromatin. Mol Cell Biol. 2014;34:3662-74 pubmed 出版商
  • 免疫印迹; 人类
Ciavardelli D, Rossi C, Barcaroli D, Volpe S, Consalvo A, Zucchelli M, et al. Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment. Cell Death Dis. 2014;5:e1336 pubmed 出版商
  • 免疫印迹; 人类; 图 5-s1
Lo Sasso G, Ryu D, Mouchiroud L, Fernando S, Anderson C, Katsyuba E, et al. Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer. PLoS ONE. 2014;9:e102495 pubmed 出版商
  • 免疫印迹; 人类
Kłossowicz M, Marek Bukowiec K, Arbulo Echevarria M, Scirka B, Majkowski M, Sikorski A, et al. Identification of functional, short-lived isoform of linker for activation of T cells (LAT). Genes Immun. 2014;15:449-56 pubmed 出版商
  • 免疫印迹; 人类
Osterman M, Kathawa D, Liu D, Guo H, Zhang C, Li M, et al. Elevated DNA damage response in pancreatic cancer. Histochem Cell Biol. 2014;142:713-20 pubmed 出版商
  • 免疫印迹; 小鼠
Gonzalez Rodriguez A, Reibert B, Amann T, Constien R, Rondinone C, Valverde A. In vivo siRNA delivery of Keap1 modulates death and survival signaling pathways and attenuates concanavalin-A-induced acute liver injury in mice. Dis Model Mech. 2014;7:1093-100 pubmed 出版商
  • 免疫印迹; 小鼠; 1:30,000
Sadleir K, Eimer W, Kaufman R, Osten P, Vassar R. Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease. PLoS ONE. 2014;9:e101643 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2
Wei X, Li J, Xie H, Wang H, Wang J, Zhang X, et al. Chloride intracellular channel 1 participates in migration and invasion of hepatocellular carcinoma by targeting maspin. J Gastroenterol Hepatol. 2015;30:208-16 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Chondrogiannis G, Kastamoulas M, Kanavaros P, Vartholomatos G, Bai M, Baltogiannis D, et al. Cytokine effects on cell viability and death of prostate carcinoma cells. Biomed Res Int. 2014;2014:536049 pubmed 出版商
  • 免疫印迹; 人类
Samartzis E, Gutsche K, Dedes K, Fink D, Stucki M, Imesch P. Loss of ARID1A expression sensitizes cancer cells to PI3K- and AKT-inhibition. Oncotarget. 2014;5:5295-303 pubmed
  • 免疫印迹; 人类
von Roemeling C, Radisky D, Marlow L, Cooper S, Grebe S, ANASTASIADIS P, et al. Neuronal pentraxin 2 supports clear cell renal cell carcinoma by activating the AMPA-selective glutamate receptor-4. Cancer Res. 2014;74:4796-810 pubmed 出版商
  • 免疫印迹; 大鼠
Fernandes J, Vieira M, Carreto L, Santos M, Duarte C, Carvalho A, et al. In vitro ischemia triggers a transcriptional response to down-regulate synaptic proteins in hippocampal neurons. PLoS ONE. 2014;9:e99958 pubmed 出版商
  • 免疫印迹; 人类
Zhao Z, Wu L, Xiong R, Wang L, Zhang B, Wang C, et al. MicroRNA-922 promotes tau phosphorylation by downregulating ubiquitin carboxy-terminal hydrolase L1 (UCHL1) expression in the pathogenesis of Alzheimer's disease. Neuroscience. 2014;275:232-7 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Tanaka T, Iino M. Sec6 regulated cytoplasmic translocation and degradation of p27 via interactions with Jab1 and Siah1. Cell Signal. 2014;26:2071-85 pubmed 出版商
  • 免疫组化; 鸡; 1:10,000; 图 s7
Herrera A, Saade M, Menendez A, Marti E, Pons S. Sustained Wnt/?-catenin signalling causes neuroepithelial aberrations through the accumulation of aPKC at the apical pole. Nat Commun. 2014;5:4168 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Cheshenko N, Trepanier J, González P, Eugenin E, Jacobs W, Herold B. Herpes simplex virus type 2 glycoprotein H interacts with integrin ?v?3 to facilitate viral entry and calcium signaling in human genital tract epithelial cells. J Virol. 2014;88:10026-38 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Price D, Ackland M, Burks W, Knight M, Suphioglu C. Peanut allergens alter intestinal barrier permeability and tight junction localisation in Caco-2 cell cultures. Cell Physiol Biochem. 2014;33:1758-77 pubmed 出版商
  • 免疫印迹; 小鼠; 1:20,000
Kaneko Y, Ota A, Nakashima A, Nagasaki H, Kodani Y, Mori K, et al. Lipopolysaccharide treatment arrests the cell cycle of BV-2 microglial cells in G? phase and protects them from UV light-induced apoptosis. J Neural Transm (Vienna). 2015;122:187-99 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s3
Etnyre D, Stone A, Fong J, Jacobs R, Uppada S, Botting G, et al. Targeting c-Met in melanoma: mechanism of resistance and efficacy of novel combinatorial inhibitor therapy. Cancer Biol Ther. 2014;15:1129-41 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
van Doremalen N, Miazgowicz K, Milne Price S, Bushmaker T, Robertson S, Scott D, et al. Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4. J Virol. 2014;88:9220-32 pubmed 出版商
  • 免疫印迹; 小鼠; 1:15,000
Devi L, Ohno M. PERK mediates eIF2? phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease. Neurobiol Aging. 2014;35:2272-81 pubmed 出版商
  • 免疫印迹; African green monkey
Fausther M, Lavoie E, Goree J, Baldini G, Dranoff J. NT5E mutations that cause human disease are associated with intracellular mistrafficking of NT5E protein. PLoS ONE. 2014;9:e98568 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Kodama T, Tsukaguchi T, Yoshida M, Kondoh O, Sakamoto H. Selective ALK inhibitor alectinib with potent antitumor activity in models of crizotinib resistance. Cancer Lett. 2014;351:215-21 pubmed 出版商
  • 免疫印迹; 人类
Cho M, Kwon S, Kim C, Lee Y, Nam H, Lee S. Overexpression of KAI1 Protein in Diabetic Skin Tissues. Arch Plast Surg. 2014;41:248-52 pubmed 出版商
  • 免疫印迹; 人类
Kadota S, Nagata K. Silencing of IFN-stimulated gene transcription is regulated by histone H1 and its chaperone TAF-I. Nucleic Acids Res. 2014;42:7642-53 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000
Zeng L, Holly J, Perks C. Effects of physiological levels of the green tea extract epigallocatechin-3-gallate on breast cancer cells. Front Endocrinol (Lausanne). 2014;5:61 pubmed 出版商
  • 免疫印迹; 小鼠
Maas N, Singh N, Diehl J. Generation and characterization of an analog-sensitive PERK allele. Cancer Biol Ther. 2014;15:1106-11 pubmed 出版商
  • 免疫印迹; 人类
Israelow B, Narbus C, Sourisseau M, Evans M. HepG2 cells mount an effective antiviral interferon-lambda based innate immune response to hepatitis C virus infection. Hepatology. 2014;60:1170-9 pubmed 出版商
  • 免疫印迹; 人类
Li S, Zhou T, Li C, Dai Z, Che D, Yao Y, et al. High metastaticgastric and breast cancer cells consume oleic acid in an AMPK dependent manner. PLoS ONE. 2014;9:e97330 pubmed 出版商
  • 免疫印迹; 小鼠
Kitagawa K, Shibata K, Matsumoto A, Matsumoto M, Ohhata T, Nakayama K, et al. Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development. Mol Cell Biol. 2014;34:2732-44 pubmed
  • 免疫印迹; 人类
Li C, Egloff A, Sen M, Grandis J, Johnson D. Caspase-8 mutations in head and neck cancer confer resistance to death receptor-mediated apoptosis and enhance migration, invasion, and tumor growth. Mol Oncol. 2014;8:1220-30 pubmed 出版商
  • 免疫印迹; 小鼠
Sreedharan R, Chen S, Miller M, Haribhai D, Williams C, Van Why S. Mice with an absent stress response are protected against ischemic renal injury. Kidney Int. 2014;86:515-24 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Senkiv Y, Riabtseva A, Heffeter P, Boiko N, Kowol C, Jungwith U, et al. Enhanced anticancer activity and circumvention of resistance mechanisms by novel polymeric/ phospholipidic nanocarriers of doxorubicin. J Biomed Nanotechnol. 2014;10:1369-81 pubmed
  • 免疫印迹; 人类; 1:10,000
Brandl C, Zimmermann S, Milenkovic V, Rosendahl S, Grassmann F, Milenkovic A, et al. In-depth characterisation of Retinal Pigment Epithelium (RPE) cells derived from human induced pluripotent stem cells (hiPSC). Neuromolecular Med. 2014;16:551-64 pubmed 出版商
  • 免疫印迹; 人类
Jacob A, Singh R, Mohammad F, Bebee T, Chandler D. The splicing factor FUBP1 is required for the efficient splicing of oncogene MDM2 pre-mRNA. J Biol Chem. 2014;289:17350-64 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000
Gruol D, Vo K, Bray J, Roberts A. CCL2-ethanol interactions and hippocampal synaptic protein expression in a transgenic mouse model. Front Integr Neurosci. 2014;8:29 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Klaus C, Kaemmerer E, Reinartz A, Schneider U, Plum P, Jeon M, et al. TP53 status regulates ACSL5-induced expression of mitochondrial mortalin in enterocytes and colorectal adenocarcinomas. Cell Tissue Res. 2014;357:267-78 pubmed 出版商
  • 免疫印迹; 人类
Coomans de Brachène A, Bollaert E, Eijkelenboom A, de Rocca Serra A, van der Vos K, Burgering B, et al. The expression of the tumour suppressor HBP1 is down-regulated by growth factors via the PI3K/PKB/FOXO pathway. Biochem J. 2014;460:25-34 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Sahlberg S, Spiegelberg D, Glimelius B, Stenerlow B, Nestor M. Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells. PLoS ONE. 2014;9:e94621 pubmed 出版商
  • 免疫印迹; 人类
Shi W, Ogbomo S, Wagh N, Zhou Z, Jia Y, Brusnahan S, et al. The influence of linker length on the properties of cathepsin S cleavable (177)Lu-labeled HPMA copolymers for pancreatic cancer imaging. Biomaterials. 2014;35:5760-70 pubmed 出版商
  • 免疫印迹; 人类; 图 4
O Sullivan D, Henry M, Joyce H, Walsh N, Mc Auley E, Dowling P, et al. 7B7: a novel antibody directed against the Ku70/Ku80 heterodimer blocks invasion in pancreatic and lung cancer cells. Tumour Biol. 2014;35:6983-97 pubmed 出版商
  • 免疫印迹; 小鼠
  • 免疫印迹; 人类
Gonzalez Rodriguez A, Mayoral R, Agra N, Valdecantos M, Pardo V, Miquilena Colina M, et al. Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD. Cell Death Dis. 2014;5:e1179 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Juan W, Roca X, Ong S. Identification of cis-acting elements and splicing factors involved in the regulation of BIM Pre-mRNA splicing. PLoS ONE. 2014;9:e95210 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:200
Calabrese B, Saffin J, Halpain S. Activity-dependent dendritic spine shrinkage and growth involve downregulation of cofilin via distinct mechanisms. PLoS ONE. 2014;9:e94787 pubmed 出版商
  • 免疫印迹; 人类; 图 s7
Veronese A, Pepe F, Chiacchia J, Pagotto S, Lanuti P, Veschi S, et al. Allele-specific loss and transcription of the miR-15a/16-1 cluster in chronic lymphocytic leukemia. Leukemia. 2015;29:86-95 pubmed 出版商
  • 免疫印迹; 大鼠
Tobin G, Zhang J, Goodwin D, Stewart S, Xu L, Knapton A, et al. The role of eNOS phosphorylation in causing drug-induced vascular injury. Toxicol Pathol. 2014;42:709-24 pubmed 出版商
  • 免疫印迹; 大鼠
Han X, Cheng D, Song F, Zeng T, An L, Xie K. Decelerated transport and its mechanism of 2,5-hexanedione on middle-molecular-weight neurofilament in rat dorsal root ganglia cells. Neuroscience. 2014;269:192-8 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000
Rodier M, Prigent Tessier A, B jot Y, Jacquin A, Mossiat C, Marie C, et al. Exogenous t-PA administration increases hippocampal mature BDNF levels. plasmin- or NMDA-dependent mechanism?. PLoS ONE. 2014;9:e92416 pubmed 出版商
  • 免疫印迹; 人类; 1:2,000
Scharfmann R, Pechberty S, Hazhouz Y, von Bülow M, Bricout Neveu E, Grenier Godard M, et al. Development of a conditionally immortalized human pancreatic ? cell line. J Clin Invest. 2014;124:2087-98 pubmed 出版商
  • 免疫印迹; 人类; 1:20,000
Balk Møller E, Kim J, Hopkinson B, Timmermans Wielenga V, Petersen O, Villadsen R. A marker of endocrine receptor-positive cells, CEACAM6, is shared by two major classes of breast cancer: luminal and HER2-enriched. Am J Pathol. 2014;184:1198-208 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1,3
Morrison J, Pike L, Sams S, Sharma V, Zhou Q, Severson J, et al. Thioredoxin interacting protein (TXNIP) is a novel tumor suppressor in thyroid cancer. Mol Cancer. 2014;13:62 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫印迹; 小鼠
Boudoukha S, Rivera Vargas T, Dang I, Kropp J, Cuvellier S, Gautreau A, et al. MiRNA let-7g regulates skeletal myoblast motility via Pinch-2. FEBS Lett. 2014;588:1623-9 pubmed 出版商
  • 免疫印迹; 牛; 1:2000
Ahmed N, Iu J, Brown C, Taylor D, Kandel R. Serum- and growth-factor-free three-dimensional culture system supports cartilage tissue formation by promoting collagen synthesis via Sox9-Col2a1 interaction. Tissue Eng Part A. 2014;20:2224-33 pubmed 出版商
  • 免疫印迹; 小鼠
Jha P, Knopf A, Koefeler H, Mueller M, Lackner C, Hoefler G, et al. Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH). Biochim Biophys Acta. 2014;1842:959-70 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Ekman M, Uvelius B, Albinsson S, Swärd K. HIF-mediated metabolic switching in bladder outlet obstruction mitigates the relaxing effect of mitochondrial inhibition. Lab Invest. 2014;94:557-68 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Fernandez Estevez M, Casarejos M, Lopez Sendon J, Garcia Caldentey J, Ruiz C, Gomez A, et al. Trehalose reverses cell malfunction in fibroblasts from normal and Huntington's disease patients caused by proteosome inhibition. PLoS ONE. 2014;9:e90202 pubmed 出版商
  • 免疫印迹; 人类
Herve D, Philippi A, Belbouab R, Zerah M, Chabrier S, Collardeau Frachon S, et al. Loss of ?1?1 soluble guanylate cyclase, the major nitric oxide receptor, leads to moyamoya and achalasia. Am J Hum Genet. 2014;94:385-94 pubmed 出版商
  • 免疫印迹; 人类; 1:7500
López Farré A, Modrego J, Azcona L, Guerra R, Segura A, Rodriguez P, et al. Nitric oxide from mononuclear cells may be involved in platelet responsiveness to aspirin. Eur J Clin Invest. 2014;44:463-9 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Nakahata S, Ichikawa T, Maneesaay P, Saito Y, Nagai K, Tamura T, et al. Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers. Nat Commun. 2014;5:3393 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 st13
Hwang W, Jiang J, Yang S, Huang T, Lan H, Teng H, et al. MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells. Nat Cell Biol. 2014;16:268-80 pubmed 出版商
  • 免疫印迹; 小鼠
Qi Y, Zhang M, Li H, Frank J, Dai L, Liu H, et al. MicroRNA-29b regulates ethanol-induced neuronal apoptosis in the developing cerebellum through SP1/RAX/PKR cascade. J Biol Chem. 2014;289:10201-10 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Maida Y, Yasukawa M, Okamoto N, Ohka S, Kinoshita K, Totoki Y, et al. Involvement of telomerase reverse transcriptase in heterochromatin maintenance. Mol Cell Biol. 2014;34:1576-93 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000
Akiyama M, Izumi H, Wang K, Yamaguchi T, Kuma A, Kitamura N, et al. Hypersensitivity to aurora kinase inhibitors in cells resistant against platinum- containing anticancer agents. Anticancer Agents Med Chem. 2014;14:1042-50 pubmed
  • 免疫印迹; 人类; 1:10,000
Muenyi C, Trivedi A, Helm C, States J. Cisplatin plus sodium arsenite and hyperthermia induces pseudo-G1 associated apoptotic cell death in ovarian cancer cells. Toxicol Sci. 2014;139:74-82 pubmed 出版商
  • 免疫印迹; 人类; 1:40,000
Kilander M, Petersen J, Andressen K, Ganji R, Levy F, Schuster J, et al. Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6. FASEB J. 2014;28:2293-305 pubmed 出版商
  • 免疫印迹; 人类
Anastasía A, Deinhardt K, Wang S, Martin L, Nichol D, Irmady K, et al. Trkb signaling in pericytes is required for cardiac microvessel stabilization. PLoS ONE. 2014;9:e87406 pubmed 出版商
  • 免疫印迹; 人类
Matthess Y, Raab M, Knecht R, Becker S, Strebhardt K. Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis. Mol Oncol. 2014;8:596-608 pubmed 出版商
  • 免疫印迹; 人类
Dhar S, Alam H, Li N, Wagner K, Chung J, Ahn Y, et al. Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells. J Biol Chem. 2014;289:7483-96 pubmed 出版商
  • 免疫印迹; 人类
Tuttle T, Hugo E, Tong W, Ben Jonathan N. Placental lactogen is expressed but is not translated into protein in breast cancer. PLoS ONE. 2014;9:e87325 pubmed 出版商
  • 免疫印迹; 人类
Prensner J, Chen W, Iyer M, Cao Q, Ma T, Han S, et al. PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer. Cancer Res. 2014;74:1651-60 pubmed 出版商
  • 免疫印迹; 小鼠
Galicia Vázquez G, Di Marco S, Lian X, Ma J, Gallouzi I, Pelletier J. Regulation of eukaryotic initiation factor 4AII by MyoD during murine myogenic cell differentiation. PLoS ONE. 2014;9:e87237 pubmed 出版商
  • 免疫印迹; 人类; 1:50,000
Jordan N, Dutkowski C, Barrow D, Mottram H, Hutcheson I, Nicholson R, et al. Impact of dual mTORC1/2 mTOR kinase inhibitor AZD8055 on acquired endocrine resistance in breast cancer in vitro. Breast Cancer Res. 2014;16:R12 pubmed 出版商
  • 免疫印迹; Burton's mouthbrooder
Kempf A, Tews B, Arzt M, Weinmann O, Obermair F, Pernet V, et al. The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. PLoS Biol. 2014;12:e1001763 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫印迹; 人类
Massimino M, Consoli M, Mesuraca M, Stagno F, Tirrò E, Stella S, et al. IRF5 is a target of BCR-ABL kinase activity and reduces CML cell proliferation. Carcinogenesis. 2014;35:1132-43 pubmed 出版商
  • 免疫细胞化学; 人类
Salvi M, Raiborg C, Hanson P, Campsteijn C, Stenmark H, Pinna L. CK2 involvement in ESCRT-III complex phosphorylation. Arch Biochem Biophys. 2014;545:83-91 pubmed 出版商
  • 免疫印迹; 小鼠; 1:4000; 图 3, 5
Wadosky K, Rodriguez J, Hite R, Min J, Walton B, Willis M. Muscle RING finger-1 attenuates IGF-I-dependent cardiomyocyte hypertrophy by inhibiting JNK signaling. Am J Physiol Endocrinol Metab. 2014;306:E723-39 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s2, s4
Denissov S, Hofemeister H, Marks H, Kranz A, Ciotta G, Singh S, et al. Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant. Development. 2014;141:526-37 pubmed 出版商
  • 免疫印迹; 家羊
Syedain Z, Meier L, Lahti M, Johnson S, Tranquillo R. Implantation of completely biological engineered grafts following decellularization into the sheep femoral artery. Tissue Eng Part A. 2014;20:1726-34 pubmed 出版商
  • 免疫印迹; 人类; 1:300
Rouhigharabaei L, Finalet Ferreiro J, Tousseyn T, van der Krogt J, Put N, Haralambieva E, et al. Non-IG aberrations of FOXP1 in B-cell malignancies lead to an aberrant expression of N-truncated isoforms of FOXP1. PLoS ONE. 2014;9:e85851 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Moore R, Tao W, Meng Y, Smith E, Xu X. Cell adhesion and sorting in embryoid bodies derived from N- or E-cadherin deficient murine embryonic stem cells. Biol Open. 2014;3:121-8 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000
Heyne K, Förster J, Schüle R, Roemer K. Transcriptional repressor NIR interacts with the p53-inhibiting ubiquitin ligase MDM2. Nucleic Acids Res. 2014;42:3565-79 pubmed 出版商
  • 免疫印迹; 人类
Stahlschmidt W, Robertson M, Robinson P, McCluskey A, Haucke V. Clathrin terminal domain-ligand interactions regulate sorting of mannose 6-phosphate receptors mediated by AP-1 and GGA adaptors. J Biol Chem. 2014;289:4906-18 pubmed 出版商
  • 免疫印迹; 人类; 1:1,000
Doherty B, Lawlor D, Gillet J, Gottesman M, O Leary J, Stordal B. Collateral sensitivity to cisplatin in KB-8-5-11 drug-resistant cancer cells. Anticancer Res. 2014;34:503-7 pubmed
  • 免疫印迹; 小鼠; 1:5000
Ziegler A, Chidambaram S, Forbes B, Wood T, Levison S. Insulin-like growth factor-II (IGF-II) and IGF-II analogs with enhanced insulin receptor-a binding affinity promote neural stem cell expansion. J Biol Chem. 2014;289:4626-33 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Ahn J, Jang J, Choi J, Lee J, Oh S, Lee J, et al. GSK3?, but not GSK3?, inhibits the neuronal differentiation of neural progenitor cells as a downstream target of mammalian target of rapamycin complex1. Stem Cells Dev. 2014;23:1121-33 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Yamanaka T, Tosaki A, Kurosawa M, Akimoto K, Hirose T, Ohno S, et al. Loss of aPKC? in differentiated neurons disrupts the polarity complex but does not induce obvious neuronal loss or disorientation in mouse brains. PLoS ONE. 2013;8:e84036 pubmed 出版商
  • 免疫组化; 小鼠
Basu S, Rajakaruna S, De Arcangelis A, Zhang L, Georges Labouesse E, Menko A. ?6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation. J Biol Chem. 2014;289:3842-55 pubmed 出版商
  • 免疫印迹; 小鼠
Borghgraef P, Menuet C, Theunis C, Louis J, Devijver H, Maurin H, et al. Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice. PLoS ONE. 2013;8:e84442 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Adhikary G, Grun D, Kerr C, Balasubramanian S, Rorke E, Vemuri M, et al. Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation. PLoS ONE. 2013;8:e84324 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Sahlberg S, Gustafsson A, Pendekanti P, Glimelius B, Stenerlow B. The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines. Tumour Biol. 2014;35:3525-34 pubmed 出版商
  • 免疫印迹; 人类
Sharma Walia N, Chandran K, Patel K, Veettil M, Marginean A. The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis. J Virol. 2014;88:2131-56 pubmed 出版商
  • 免疫印迹; 小鼠
Xavier J, Morgado A, Sola S, Rodrigues C. Mitochondrial translocation of p53 modulates neuronal fate by preventing differentiation-induced mitochondrial stress. Antioxid Redox Signal. 2014;21:1009-24 pubmed 出版商
  • 免疫印迹; 人类
Feng Y, Wu H, Xu Y, Zhang Z, Liu T, Lin X, et al. Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-? signaling. J Biol Chem. 2014;289:2072-83 pubmed 出版商
  • 免疫印迹; 人类
Wu C, Ko J, Chen S, Lin Y, Han C, Yang T, et al. Clinical implications of aldo-keto reductase family 1 member C3 and its relationship with lipocalin 2 in cancer of the uterine cervix. Gynecol Oncol. 2014;132:474-82 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Holtzhausen A, Golzio C, How T, Lee Y, Schiemann W, Katsanis N, et al. Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development. FASEB J. 2014;28:1248-67 pubmed 出版商
  • 免疫印迹; 人类
Wagner M, Koslowski M, Paret C, Schmidt M, Tureci O, Sahin U. NCOA3 is a selective co-activator of estrogen receptor ?-mediated transactivation of PLAC1 in MCF-7 breast cancer cells. BMC Cancer. 2013;13:570 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Tanaka T, Iino M. Knockdown of Sec8 promotes cell-cycle arrest at G1/S phase by inducing p21 via control of FOXO proteins. FEBS J. 2014;281:1068-84 pubmed 出版商
  • 免疫印迹; 小鼠
Sandow J, Dorstyn L, O Reilly L, Tailler M, Kumar S, Strasser A, et al. ER stress does not cause upregulation and activation of caspase-2 to initiate apoptosis. Cell Death Differ. 2014;21:475-80 pubmed 出版商
  • 免疫印迹; 大鼠; 1:7000
Nakajima T, Yanagihara M, Nishii H. Temporal and regional patterns of Smad activation in the rat hippocampus following global ischemia. J Neurol Sci. 2014;337:25-37 pubmed 出版商
  • 免疫印迹; 人类
Lam T, Thomas L, White C, Li G, Pone E, Xu Z, et al. Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination. PLoS ONE. 2013;8:e80414 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Rubio N, Verrax J, Dewaele M, Verfaillie T, Johansen T, Piette J, et al. p38(MAPK)-regulated induction of p62 and NBR1 after photodynamic therapy promotes autophagic clearance of ubiquitin aggregates and reduces reactive oxygen species levels by supporting Nrf2-antioxidant signaling. Free Radic Biol Med. 2014;67:292-303 pubmed 出版商
  • 免疫印迹; 人类
Han J, Rho S, Lee J, Bae J, Park S, Lee S, et al. Human cytomegalovirus (HCMV) US2 protein interacts with human CD1d (hCD1d) and down-regulates invariant NKT (iNKT) cell activity. Mol Cells. 2013;36:455-64 pubmed 出版商
  • 免疫印迹; 人类
Singh A, Zapata M, Choi Y, Yoon S. GSI promotes vincristine-induced apoptosis by enhancing multi-polar spindle formation. Cell Cycle. 2014;13:157-66 pubmed 出版商
  • 免疫印迹; 人类
Wu H, Balsbaugh J, Chandler H, Georgilis A, Zullow H, Shabanowitz J, et al. Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7. J Biol Chem. 2013;288:36398-408 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 5
Formosa A, Markert E, Lena A, Italiano D, Finazzi Agrò E, Levine A, et al. MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells. Oncogene. 2014;33:5173-82 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 6, 7
Bana E, Sibille E, Valente S, Cerella C, Chaimbault P, Kirsch G, et al. A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death. Mol Carcinog. 2015;54:229-41 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Gastaldello S, Chen X, Callegari S, Masucci M. Caspase-1 promotes Epstein-Barr virus replication by targeting the large tegument protein deneddylase to the nucleus of productively infected cells. PLoS Pathog. 2013;9:e1003664 pubmed 出版商
  • 免疫印迹; 小鼠
Ni H, Du K, You M, Ding W. Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity. Am J Pathol. 2013;183:1815-1825 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000
Bray K, Gillette M, Young J, Loughran E, Hwang M, Sears J, et al. Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration. Breast Cancer Res. 2013;15:R91 pubmed
  • 免疫印迹; 小鼠
Soler A, Serra H, Pearce W, Angulo A, Guillermet Guibert J, Friedman L, et al. Inhibition of the p110? isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis. J Exp Med. 2013;210:1937-45 pubmed 出版商
  • 免疫印迹; 人类; 1:2000
Fatemi S, Folsom T, Rooney R, Thuras P. Expression of GABAA ?2-, ?1- and ?-receptors are altered significantly in the lateral cerebellum of subjects with schizophrenia, major depression and bipolar disorder. Transl Psychiatry. 2013;3:e303 pubmed 出版商
  • 免疫印迹; 大鼠
Yi X, Pashaj A, Xia M, Moreau R. Reversal of obesity-induced hypertriglyceridemia by (R)-?-lipoic acid in ZDF (fa/fa) rats. Biochem Biophys Res Commun. 2013;439:390-5 pubmed 出版商
  • 免疫印迹; 小鼠
Subramanian V, Moorleghen J, Balakrishnan A, Howatt D, Chishti A, Uchida H. Calpain-2 compensation promotes angiotensin II-induced ascending and abdominal aortic aneurysms in calpain-1 deficient mice. PLoS ONE. 2013;8:e72214 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000
O Brien M, Carbin S, Morrison J, Smith T. Decreased myometrial p160 ROCK-1 expression in obese women at term pregnancy. Reprod Biol Endocrinol. 2013;11:79 pubmed 出版商
  • 免疫印迹; 人类
Garcia Jove Navarro M, Basset C, Arcondeguy T, Touriol C, Perez G, Prats H, et al. Api5 contributes to E2F1 control of the G1/S cell cycle phase transition. PLoS ONE. 2013;8:e71443 pubmed 出版商
  • 免疫印迹; 小鼠
Gurung B, Feng Z, Hua X. Menin directly represses Gli1 expression independent of canonical Hedgehog signaling. Mol Cancer Res. 2013;11:1215-22 pubmed 出版商
  • 免疫印迹; 人类
Bucur O, Pennarun B, Stancu A, Nadler M, Muraru M, Bertomeu T, et al. Poor antibody validation is a challenge in biomedical research: a case study for detection of c-FLIP. Apoptosis. 2013;18:1154-62 pubmed 出版商
  • 免疫印迹; 人类; 1:20,000
Wong K, Gascoyne D, Brown P, Soilleux E, Snell C, Chen H, et al. Reciprocal expression of the endocytic protein HIP1R and its repressor FOXP1 predicts outcome in R-CHOP-treated diffuse large B-cell lymphoma patients. Leukemia. 2014;28:362-72 pubmed 出版商
  • 免疫印迹; 小鼠; 1:15,000
Devi L, Ohno M. Mechanisms that lessen benefits of ?-secretase reduction in a mouse model of Alzheimer's disease. Transl Psychiatry. 2013;3:e284 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1
Gurkar A, Chu K, Raj L, Bouley R, Lee S, Kim Y, et al. Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress. Nat Commun. 2013;4:2189 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000
Montiel V, León Gómez E, Bouzin C, Esfahani H, Romero Pérez M, Lobysheva I, et al. Genetic deletion of aquaporin-1 results in microcardia and low blood pressure in mouse with intact nitric oxide-dependent relaxation, but enhanced prostanoids-dependent relaxation. Pflugers Arch. 2014;466:237-51 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠
  • 免疫印迹; 小鼠; 1:1000
Roux C, Lesueur C, Aligny C, Brasse Lagnel C, Genty D, Marret S, et al. 3-MA inhibits autophagy and favors long-term integration of grafted Gad67-GFP GABAergic precursors in the developing neocortex by preventing apoptosis. Cell Transplant. 2014;23:1425-50 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 2
Hafko R, Villapol S, Nostramo R, Symes A, Sabban E, Inagami T, et al. Commercially available angiotensin II At? receptor antibodies are nonspecific. PLoS ONE. 2013;8:e69234 pubmed 出版商
  • 免疫印迹; 小鼠
Puglisi F, Vanni V, Ponterio G, Tassone A, Sciamanna G, Bonsi P, et al. Torsin A Localization in the Mouse Cerebellar Synaptic Circuitry. PLoS ONE. 2013;8:e68063 pubmed 出版商
  • 免疫印迹; 人类; 1:100,000
Hou P, Chuang C, Kao C, Chou S, Stone L, Ho H, et al. LHX2 regulates the neural differentiation of human embryonic stem cells via transcriptional modulation of PAX6 and CER1. Nucleic Acids Res. 2013;41:7753-70 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Luijten M, Basten S, Claessens T, Vernooij M, Scott C, Janssen R, et al. Birt-Hogg-Dube syndrome is a novel ciliopathy. Hum Mol Genet. 2013;22:4383-97 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Fatemi S, Folsom T, Rooney R, Thuras P. mRNA and protein expression for novel GABAA receptors ? and ?2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway. Transl Psychiatry. 2013;3:e271 pubmed 出版商
  • 免疫印迹; 人类
Rajendran P, Kidane A, Yu T, Dashwood W, Bisson W, LOHR C, et al. HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates. Epigenetics. 2013;8:612-23 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Shibata K, Nakahara S, Shimizu E, Yamashita T, Matsuki N, Koyama R. Repulsive guidance molecule a regulates hippocampal mossy fiber branching in vitro. Neuroreport. 2013;24:609-15 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Zhang X, Hernandez I, Rei D, Mair W, Laha J, Cornwell M, et al. Diaminothiazoles modify Tau phosphorylation and improve the tauopathy in mouse models. J Biol Chem. 2013;288:22042-56 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Gillette M, Bray K, Blumenthaler A, Vargo Gogola T. P190B RhoGAP overexpression in the developing mammary epithelium induces TGF?-dependent fibroblast activation. PLoS ONE. 2013;8:e65105 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Takasugi M, Hayakawa K, Arai D, Shiota K. Age- and sex-dependent DNA hypomethylation controlled by growth hormone in mouse liver. Mech Ageing Dev. 2013;134:331-7 pubmed 出版商
  • 免疫印迹; 人类
Huang B, Ray P, Iwasaki K, Tsuji Y. Transcriptional regulation of the human ferritin gene by coordinated regulation of Nrf2 and protein arginine methyltransferases PRMT1 and PRMT4. FASEB J. 2013;27:3763-74 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Mobasher M, Gonzalez Rodriguez A, Santamaria B, Ramos S, Martin M, Goya L, et al. Protein tyrosine phosphatase 1B modulates GSK3?/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity. Cell Death Dis. 2013;4:e626 pubmed 出版商
  • 免疫印迹; 人类
Sharma A, Diecke S, Zhang W, Lan F, He C, Mordwinkin N, et al. The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. J Biol Chem. 2013;288:18439-47 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000
Nguyen H, Hübener J, Weber J, Grueninger S, Riess O, Weiss A. Cerebellar soluble mutant ataxin-3 level decreases during disease progression in Spinocerebellar Ataxia Type 3 mice. PLoS ONE. 2013;8:e62043 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Park Y, Ko J, Jang Y, Kwon Y. Activation of AMP-activated protein kinase alleviates homocysteine-mediated neurotoxicity in SH-SY5Y cells. Neurochem Res. 2013;38:1561-71 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Moreno A, Soleto I, García Sanz P, Moreno Bueno G, Palmero I. ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth. Oncogene. 2014;33:1945-53 pubmed 出版商
  • 免疫印迹; 大鼠; 图 4
Rodriguez Martin T, Cuchillo Ibanez I, Noble W, Nyenya F, Anderton B, Hanger D. Tau phosphorylation affects its axonal transport and degradation. Neurobiol Aging. 2013;34:2146-57 pubmed 出版商
  • 免疫印迹; 小鼠
Mandemakers W, Abuhatzira L, Xu H, Caromile L, Hébert S, Snellinx A, et al. Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2 ?: identification of miR-153 target genes with functions related to IA-2? in pancreas and brain. Diabetologia. 2013;56:1547-56 pubmed 出版商
  • 免疫印迹; 人类; 1:20,000
Ipenberg I, Guttmann Raviv N, Khoury H, Kupershmit I, Ayoub N. Heat shock protein 90 (Hsp90) selectively regulates the stability of KDM4B/JMJD2B histone demethylase. J Biol Chem. 2013;288:14681-7 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Vanoirbeek E, Eelen G, Verlinden L, Carmeliet G, Mathieu C, Bouillon R, et al. PDLIM2 expression is driven by vitamin D and is involved in the pro-adhesion, and anti-migration and -invasion activity of vitamin D. Oncogene. 2014;33:1904-11 pubmed 出版商
  • 免疫印迹; 人类
Gurung B, Feng Z, Iwamoto D, Thiel A, Jin G, Fan C, et al. Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome. Cancer Res. 2013;73:2650-8 pubmed 出版商
  • 免疫印迹; 人类
Avena P, Anselmo W, Whitaker Menezes D, Wang C, Pestell R, Lamb R, et al. Compartment-specific activation of PPAR? governs breast cancer tumor growth, via metabolic reprogramming and symbiosis. Cell Cycle. 2013;12:1360-70 pubmed 出版商
  • 免疫印迹; 人类; 1:6000
Ward J, Rider V, Abdou N, Kimler B. Estradiol differentially regulates calreticulin: a potential link with abnormal T cell function in systemic lupus erythematosus?. Lupus. 2013;22:583-96 pubmed 出版商
  • 免疫印迹; 小鼠
Mitterberger M, Zwerschke W. Mechanisms of resveratrol-induced inhibition of clonal expansion and terminal adipogenic differentiation in 3T3-L1 preadipocytes. J Gerontol A Biol Sci Med Sci. 2013;68:1356-76 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Fu H, Sohail A, Valiathan R, Wasinski B, Kumarasiri M, Mahasenan K, et al. Shedding of discoidin domain receptor 1 by membrane-type matrix metalloproteinases. J Biol Chem. 2013;288:12114-29 pubmed 出版商
  • 免疫印迹; 人类
Dellago H, Preschitz Kammerhofer B, Terlecki Zaniewicz L, Schreiner C, Fortschegger K, Chang M, et al. High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan. Aging Cell. 2013;12:446-58 pubmed 出版商
  • 免疫印迹; 小鼠
Yamada H, Abe T, Satoh A, Okazaki N, Tago S, Kobayashi K, et al. Stabilization of actin bundles by a dynamin 1/cortactin ring complex is necessary for growth cone filopodia. J Neurosci. 2013;33:4514-26 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类; 图 6b
Werwein E, Dzuganova M, Usadel C, Klempnauer K. B-Myb switches from Cyclin/Cdk-dependent to Jnk- and p38 kinase-dependent phosphorylation and associates with SC35 bodies after UV stress. Cell Death Dis. 2013;4:e511 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Caldon C, Sergio C, Burgess A, Deans A, Sutherland R, Musgrove E. Cyclin E2 induces genomic instability by mechanisms distinct from cyclin E1. Cell Cycle. 2013;12:606-17 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000
Petrie C, Smithson L, Crotty A, Michalski B, Fahnestock M, Kawaja M. Overexpression of nerve growth factor by murine smooth muscle cells: role of the p75 neurotrophin receptor on sympathetic and sensory sprouting. J Comp Neurol. 2013;521:2621-43 pubmed 出版商
  • 免疫印迹; 人类
Balaburski G, Leu J, Beeharry N, Hayik S, Andrake M, Zhang G, et al. A modified HSP70 inhibitor shows broad activity as an anticancer agent. Mol Cancer Res. 2013;11:219-29 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Maute R, Schneider C, Sumazin P, Holmes A, Califano A, Basso K, et al. tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma. Proc Natl Acad Sci U S A. 2013;110:1404-9 pubmed 出版商
  • 免疫印迹; 人类
Ogiwara H, Kohno T. CBP and p300 histone acetyltransferases contribute to homologous recombination by transcriptionally activating the BRCA1 and RAD51 genes. PLoS ONE. 2012;7:e52810 pubmed 出版商
  • 免疫印迹; 小鼠
Nagakura A, Shitaka Y, Yarimizu J, Matsuoka N. Characterization of cognitive deficits in a transgenic mouse model of Alzheimer's disease and effects of donepezil and memantine. Eur J Pharmacol. 2013;703:53-61 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Sánchez Alvarez R, Martinez Outschoorn U, Lin Z, Lamb R, Hulit J, Howell A, et al. Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention. Cell Cycle. 2013;12:289-301 pubmed 出版商
  • 免疫印迹; 人类
Sánchez Alvarez R, Martinez Outschoorn U, Lamb R, Hulit J, Howell A, Gandara R, et al. Mitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin. Cell Cycle. 2013;12:172-82 pubmed 出版商
  • 免疫印迹; 人类
Landry W, Woolley J, Cotter T. Imatinib and Nilotinib inhibit Bcr-Abl-induced ROS through targeted degradation of the NADPH oxidase subunit p22phox. Leuk Res. 2013;37:183-9 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Ballarino M, Jobert L, Dembele D, de la Grange P, Auboeuf D, Tora L. TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs. Oncogene. 2013;32:4646-55 pubmed 出版商
  • 免疫印迹; 大鼠; 1:3000
Godinho B, Ogier J, Darcy R, O Driscoll C, Cryan J. Self-assembling modified ?-cyclodextrin nanoparticles as neuronal siRNA delivery vectors: focus on Huntington's disease. Mol Pharm. 2013;10:640-9 pubmed 出版商
  • 免疫印迹; 小鼠
Einheber S, MENG X, Rubin M, Lam I, Mohandas N, An X, et al. The 4.1B cytoskeletal protein regulates the domain organization and sheath thickness of myelinated axons. Glia. 2013;61:240-53 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Gallo M, Ho J, Coutinho F, Vanner R, Lee L, Head R, et al. A tumorigenic MLL-homeobox network in human glioblastoma stem cells. Cancer Res. 2013;73:417-27 pubmed 出版商
  • 免疫印迹; 大鼠; 1:10,000
Oliva A, Kang Y, Furones C, Alonso O, Bruno O, Dietrich W, et al. Phosphodiesterase isoform-specific expression induced by traumatic brain injury. J Neurochem. 2012;123:1019-29 pubmed 出版商
  • 免疫印迹; 斑马鱼
Wu S, Shin J, Sepich D, Solnica Krezel L. Chemokine GPCR signaling inhibits β-catenin during zebrafish axis formation. PLoS Biol. 2012;10:e1001403 pubmed 出版商
  • 免疫印迹; 人类
Salem A, Howell A, Sartini M, Sotgia F, Lisanti M. Downregulation of stromal BRCA1 drives breast cancer tumor growth via upregulation of HIF-1?, autophagy and ketone body production. Cell Cycle. 2012;11:4167-73 pubmed 出版商
  • 免疫印迹; 人类
Marchetti P, Lupi R, Bugliani M, Kirkpatrick C, Sebastiani G, Grieco F, et al. A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets. Diabetologia. 2012;55:3262-72 pubmed 出版商
  • 免疫印迹; 人类; 1:2000
Takahashi A, Torigoe T, Tamura Y, Kanaseki T, Tsukahara T, Sasaki Y, et al. Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes. Cell Stress Chaperones. 2012;17:757-63 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000
Deschacht M, Van Assche T, Hendrickx S, Bult H, Maes L, Cos P. Role of oxidative stress and apoptosis in the cellular response of murine macrophages upon Leishmania infection. Parasitology. 2012;139:1429-37 pubmed 出版商
  • 免疫沉淀; 小鼠
Chao H, Lai Y, Lu Y, Lin C, Mai W, Huang Y. NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3. Nucleic Acids Res. 2012;40:8484-98 pubmed
  • 免疫组化; 小鼠
Osterloh J, Yang J, Rooney T, Fox A, Adalbert R, Powell E, et al. dSarm/Sarm1 is required for activation of an injury-induced axon death pathway. Science. 2012;337:481-4 pubmed 出版商
  • 免疫印迹; 小鼠
Shimada I, LeComte M, Granger J, Quinlan N, Spees J. Self-renewal and differentiation of reactive astrocyte-derived neural stem/progenitor cells isolated from the cortical peri-infarct area after stroke. J Neurosci. 2012;32:7926-40 pubmed 出版商
  • 免疫印迹; 人类
Wu C, Tang S, Wang P, Lee H, Ko J. Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation. J Biol Chem. 2012;287:25292-302 pubmed 出版商
  • 免疫组化基因敲除验证; 小鼠; 图 1c
  • 免疫印迹基因敲除验证; 小鼠; 图 1f
  • 免疫组化; 人类; 图 1c
Tondeleir D, Lambrechts A, Muller M, Jonckheere V, Doll T, Vandamme D, et al. Cells lacking ?-actin are genetically reprogrammed and maintain conditional migratory capacity. Mol Cell Proteomics. 2012;11:255-71 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Zhou F, Zhang X, van Dam H, Ten Dijke P, Huang H, Zhang L. Ubiquitin-specific protease 4 mitigates Toll-like/interleukin-1 receptor signaling and regulates innate immune activation. J Biol Chem. 2012;287:11002-10 pubmed 出版商
  • 染色质免疫沉淀 ; 犬
Badeaux A, Yang Y, Cardenas K, Vemulapalli V, Chen K, Kusewitt D, et al. Loss of the methyl lysine effector protein PHF20 impacts the expression of genes regulated by the lysine acetyltransferase MOF. J Biol Chem. 2012;287:429-37 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000
Balsas P, Galán Malo P, Marzo I, Naval J. Bortezomib resistance in a myeloma cell line is associated to PSM?5 overexpression and polyploidy. Leuk Res. 2012;36:212-8 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • EMSA; 人类
Wang W, Wu S, Lee A, Chiang C. Binding site specificity and factor redundancy in activator protein-1-driven human papillomavirus chromatin-dependent transcription. J Biol Chem. 2011;286:40974-86 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 2
Bunnell T, Burbach B, Shimizu Y, Ervasti J. ?-Actin specifically controls cell growth, migration, and the G-actin pool. Mol Biol Cell. 2011;22:4047-58 pubmed 出版商
  • 免疫印迹; 人类
Wang Z, Zhang Y, Zhang S, Guo Q, Tan Y, Wang X, et al. DJ-1 can inhibit microtubule associated protein 1 B formed aggregates. Mol Neurodegener. 2011;6:38 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Ariumi Y, Kuroki M, Kushima Y, Osugi K, Hijikata M, Maki M, et al. Hepatitis C virus hijacks P-body and stress granule components around lipid droplets. J Virol. 2011;85:6882-92 pubmed 出版商
  • 免疫印迹; 小鼠; 1:4000
Mouton Liger F, Thomas S, Rattenbach R, Magnol L, Larigaldie V, Ledru A, et al. PCP4 (PEP19) overexpression induces premature neuronal differentiation associated with Ca(2+) /calmodulin-dependent kinase II-? activation in mouse models of Down syndrome. J Comp Neurol. 2011;519:2779-802 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000
Kawaja M, Smithson L, Elliott J, Trinh G, Crotty A, Michalski B, et al. Nerve growth factor promoter activity revealed in mice expressing enhanced green fluorescent protein. J Comp Neurol. 2011;519:2522-45 pubmed 出版商
  • 免疫印迹; 人类
Karius T, Schnekenburger M, Ghelfi J, Walter J, Dicato M, Diederich M. Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines. Biochem Pharmacol. 2011;81:1329-42 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Wan F, Weaver A, Gao X, Bern M, Hardwidge P, Lenardo M. IKK? phosphorylation regulates RPS3 nuclear translocation and NF-?B function during infection with Escherichia coli strain O157:H7. Nat Immunol. 2011;12:335-43 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s16
Kapoor A, Goldberg M, Cumberland L, Ratnakumar K, Segura M, Emanuel P, et al. The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature. 2010;468:1105-9 pubmed 出版商
  • 免疫印迹; 人类
Day T, Palle K, Barkley L, Kakusho N, Zou Y, Tateishi S, et al. Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication. J Cell Biol. 2010;191:953-66 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Modi H, Li L, Chu S, Rossi J, Yee J, Bhatia R. Inhibition of Grb2 expression demonstrates an important role in BCR-ABL-mediated MAPK activation and transformation of primary human hematopoietic cells. Leukemia. 2011;25:305-12 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000
Schwartz C, Cheng A, Mughal M, Mattson M, Yao P. Clathrin assembly proteins AP180 and CALM in the embryonic rat brain. J Comp Neurol. 2010;518:3803-18 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 4
Kurz A, Double K, Lastres Becker I, Tozzi A, Tantucci M, Bockhart V, et al. A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old mice. PLoS ONE. 2010;5:e11464 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 2
Magnus N, Garnier D, Rak J. Oncogenic epidermal growth factor receptor up-regulates multiple elements of the tissue factor signaling pathway in human glioma cells. Blood. 2010;116:815-8 pubmed 出版商
  • 免疫印迹; 人类
Wang W, Schwemmers S, Hexner E, Pahl H. AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2. Blood. 2010;116:254-66 pubmed 出版商
  • 免疫印迹; 人类
Koschny R, Holland H, Sykora J, Erdal H, Krupp W, Bauer M, et al. Bortezomib sensitizes primary human esthesioneuroblastoma cells to TRAIL-induced apoptosis. J Neurooncol. 2010;97:171-85 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500,000
Furmanski O, Gajavelli S, Lee J, Collado M, Jergova S, Sagen J. Combined extrinsic and intrinsic manipulations exert complementary neuronal enrichment in embryonic rat neural precursor cultures: an in vitro and in vivo analysis. J Comp Neurol. 2009;515:56-71 pubmed 出版商
  • 免疫印迹; 人类
Nichols G, Schaack J, Ornelles D. Widespread phosphorylation of histone H2AX by species C adenovirus infection requires viral DNA replication. J Virol. 2009;83:5987-98 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000
Zhang J, Kundu M, Ney P. Mitophagy in mammalian cells: the reticulocyte model. Methods Enzymol. 2009;452:227-45 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000
Tuomela S, Rautajoki K, Moulder R, Nyman T, Lahesmaa R. Identification of novel Stat6 regulated proteins in IL-4-treated mouse lymphocytes. Proteomics. 2009;9:1087-98 pubmed 出版商
  • 免疫印迹; 小鼠
Ito K, Inoue K, Bae S, Ito Y. Runx3 expression in gastrointestinal tract epithelium: resolving the controversy. Oncogene. 2009;28:1379-84 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000
Papadeas S, Halloran C, McCown T, Breese G, Blake B. Changes in apical dendritic structure correlate with sustained ERK1/2 phosphorylation in medial prefrontal cortex of a rat model of dopamine D1 receptor agonist sensitization. J Comp Neurol. 2008;511:271-85 pubmed 出版商
  • 免疫印迹; 人类
Sejersen H, Rattan S. Dicarbonyl-induced accelerated aging in vitro in human skin fibroblasts. Biogerontology. 2009;10:203-11 pubmed 出版商
  • 免疫印迹; 人类
Sui J, Zhang J, Tan T, Ching C, Chen W. Comparative proteomics analysis of vascular smooth muscle cells incubated with S- and R-enantiomers of atenolol using iTRAQ-coupled two-dimensional LC-MS/MS. Mol Cell Proteomics. 2008;7:1007-18 pubmed 出版商
  • 免疫印迹; 人类
Strauss G, Westhoff M, Fischer Posovszky P, Fulda S, Schanbacher M, Eckhoff S, et al. 4-hydroperoxy-cyclophosphamide mediates caspase-independent T-cell apoptosis involving oxidative stress-induced nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG. Cell Death Differ. 2008;15:332-43 pubmed
  • 免疫印迹; 小鼠
Daniele L, Adams R, Durante D, Pugh E, Philp N. Novel distribution of junctional adhesion molecule-C in the neural retina and retinal pigment epithelium. J Comp Neurol. 2007;505:166-76 pubmed
  • 免疫印迹; 人类
Koschny R, Ganten T, Sykora J, Haas T, Sprick M, Kolb A, et al. TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window. Hepatology. 2007;45:649-58 pubmed
  • 免疫印迹; 人类
Spada F, Haemmer A, Kuch D, Rothbauer U, Schermelleh L, Kremmer E, et al. DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells. J Cell Biol. 2007;176:565-71 pubmed
  • 免疫印迹; 人类
Tanno B, Vitali R, De Arcangelis D, Mancini C, Eleuteri P, Dominici C, et al. Bim-dependent apoptosis follows IGFBP-5 down-regulation in neuroblastoma cells. Biochem Biophys Res Commun. 2006;351:547-52 pubmed
  • 免疫印迹; 大鼠; 1:5,000
Han H, Karabiyikoglu M, Kelly S, Sobel R, Yenari M. Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke. J Cereb Blood Flow Metab. 2003;23:589-98 pubmed
  • 免疫印迹; 人类
Shinoura N, Sakurai S, Shibasaki F, Asai A, Kirino T, Hamada H. Co-transduction of Apaf-1 and caspase-9 highly enhances p53-mediated apoptosis in gliomas. Br J Cancer. 2002;86:587-95 pubmed
  • 免疫印迹; 人类
Shinoura N, Sakurai S, Asai A, Kirino T, Hamada H. Over-expression of APAF-1 and caspase-9 augments radiation-induced apoptosis in U-373MG glioma cells. Int J Cancer. 2001;93:252-61 pubmed
  • 免疫印迹; 人类
Shinoura N, Sakurai S, Asai A, Kirino T, Hamada H. Co-transduction of Apaf-1 and caspase-9 augments etoposide-induced apoptosis in U-373MG glioma cells. Jpn J Cancer Res. 2001;92:467-74 pubmed
Schmitt D, Curtis S, Lyons A, Zhang J, Chen M, He C, et al. Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter. Nat Commun. 2022;13:3856 pubmed 出版商
Tan H, Lu G, Dong H, Cho Y, Natalia A, Wang L, et al. A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery. Nat Commun. 2022;13:3720 pubmed 出版商
Yamashita N, Fushimi A, Morimoto Y, Bhattacharya A, Hagiwara M, Yamamoto M, et al. Targeting MUC1-C Suppresses Chronic Activation of Cytosolic Nucleotide Receptors and STING in Triple-Negative Breast Cancer. Cancers (Basel). 2022;14: pubmed 出版商
Yin K, Patten D, Gough S, de Barros Gonçalves S, Chan A, Olan I, et al. Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance. Genes Dev. 2022;36:533-549 pubmed 出版商
Yamakawa K, Koyanagi Aoi M, Uehara K, Masuda A, Yanagimoto H, Toyama H, et al. Increased expression of SPRR1A is associated with a poor prognosis in pancreatic ductal adenocarcinoma. PLoS ONE. 2022;17:e0266620 pubmed 出版商
Azarnia Tehran D, Kochlamazashvili G, Pampaloni N, Sposini S, Shergill J, Lehmann M, et al. Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity. Sci Adv. 2022;8:eabl5032 pubmed 出版商
Demirbag Sarikaya S, Akkoç Y, Turgut S, Erbil Bilir S, Kocaturk N, Dengjel J, et al. A novel ATG5 interaction with Ku70 potentiates DNA repair upon genotoxic stress. Sci Rep. 2022;12:8134 pubmed 出版商
Fan Y, Zhao L, Lai Y, Lu K, Huang J. CRISPR-Cas9-mediated loss of function of β-catenin attenuates intervertebral disc degeneration. Mol Ther Nucleic Acids. 2022;28:387-396 pubmed 出版商
Boudreault S, Durand M, Martineau C, Perreault J, Lemay G, Bisaillon M. Reovirus μ2 protein modulates host cell alternative splicing by reducing protein levels of U5 snRNP core components. Nucleic Acids Res. 2022;50:5263-5281 pubmed 出版商
Belaidi A, Masaldan S, Southon A, Kalinowski P, Acevedo K, Appukuttan A, et al. Apolipoprotein E potently inhibits ferroptosis by blocking ferritinophagy. Mol Psychiatry. 2022;: pubmed 出版商
Liu X, Wills C, Chen L, Zhang J, Zhao Y, Zhou M, et al. Small extracellular vesicles induce resistance to anti-GD2 immunotherapy unveiling tipifarnib as an adjunct to neuroblastoma immunotherapy. J Immunother Cancer. 2022;10: pubmed 出版商
Heilmann E, Costacurta F, Geley S, Mogadashi S, Volland A, Rupp B, et al. A VSV-based assay quantifies coronavirus Mpro/3CLpro/Nsp5 main protease activity and chemical inhibition. Commun Biol. 2022;5:391 pubmed 出版商
Zakharova V, Magnitov M, Del Maestro L, Ulianov S, Glentis A, Uyanik B, et al. SETDB1 fuels the lung cancer phenotype by modulating epigenome, 3D genome organization and chromatin mechanical properties. Nucleic Acids Res. 2022;: pubmed 出版商
Lemster A, Sievers E, Pasternack H, Lazar Karsten P, Klümper N, Sailer V, et al. Histone Demethylase KDM5C Drives Prostate Cancer Progression by Promoting EMT. Cancers (Basel). 2022;14: pubmed 出版商
Daoud M, Broxtermann P, Schorn F, Werthenbach J, Seeger J, Schiffmann L, et al. XIAP promotes melanoma growth by inducing tumour neutrophil infiltration. EMBO Rep. 2022;23:e53608 pubmed 出版商
Brown M, Laouteouet D, Delobel M, Villard O, Broca C, Bertrand G, et al. The nuclear receptor REV-ERBα is implicated in the alteration of β-cell autophagy and survival under diabetogenic conditions. Cell Death Dis. 2022;13:353 pubmed 出版商
Ke P, Chang C, Hsiao Y. Baicalein Activates Parkin-Dependent Mitophagy through NDP52 and OPTN. Cells. 2022;11: pubmed 出版商
Pladevall Morera D, Castejón Griñán M, Aguilera P, Gaardahl K, Ingham A, Brosnan Cashman J, et al. ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors. Cancers (Basel). 2022;14: pubmed 出版商
Zhang N, Huang J, Xu M, Wang Y. LncRNA T-UCR Uc.339/miR-339/SLC7A11 Axis Regulates the Metastasis of Ferroptosis-Induced Lung Adenocarcinoma. J Cancer. 2022;13:1945-1957 pubmed 出版商
Niu X, Cui H, Gu X, Wu T, Sun M, Zhou C, et al. Nuclear Receptor PXR Confers Irradiation Resistance by Promoting DNA Damage Response Through Stabilization of ATF3. Front Oncol. 2022;12:837980 pubmed 出版商
Collier A, Bendall A, Fabian C, Malcolm A, Tilgner K, Semprich C, et al. Genome-wide screening identifies Polycomb repressive complex 1.3 as an essential regulator of human naïve pluripotent cell reprogramming. Sci Adv. 2022;8:eabk0013 pubmed 出版商
Zhao Y, Huang F, Zou Z, Bi Y, Yang Y, Zhang C, et al. Avian influenza viruses suppress innate immunity by inducing trans-transcriptional readthrough via SSU72. Cell Mol Immunol. 2022;19:702-714 pubmed 出版商
Peters F, Ebner L, Atac D, Maggi J, Berger W, den Hollander A, et al. Regulation of ABCA1 by AMD-Associated Genetic Variants and Hypoxia in iPSC-RPE. Int J Mol Sci. 2022;23: pubmed 出版商
Nelson L, Castro K, Xu B, Li J, Dinh N, Thompson J, et al. Synthetic lethality of cyclin-dependent kinase inhibitor Dinaciclib with VHL-deficiency allows for selective targeting of clear cell renal cell carcinoma. Cell Cycle. 2022;21:1103-1119 pubmed 出版商
Ferrucci V, De Antonellis P, Quarantelli F, Asadzadeh F, Bibbò F, Siciliano R, et al. Loss of Detection of sgN Precedes Viral Abridged Replication in COVID-19-Affected Patients-A Target for SARS-CoV-2 Propagation. Int J Mol Sci. 2022;23: pubmed 出版商
Cui X, Nilsson K, Kajitani N, Schwartz S. Overexpression of m6A-factors METTL3, ALKBH5, and YTHDC1 alters HPV16 mRNA splicing. Virus Genes. 2022;58:98-112 pubmed 出版商
Ma R, Gong D, You H, Xu C, Lu Y, Bergers G, et al. LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland. Cell Rep. 2022;38:110375 pubmed 出版商
Song N, Lee A, Yasmeen R, Shen Q, Yang K, Kumar S, et al. Epiregulin as an Alternative Ligand for Leptin Receptor Alleviates Glucose Intolerance without Change in Obesity. Cells. 2022;11: pubmed 出版商
Maldotti M, Lauria A, Anselmi F, Molineris I, Tamburrini A, Meng G, et al. The acetyltransferase p300 is recruited in trans to multiple enhancer sites by lncSmad7. Nucleic Acids Res. 2022;50:2587-2602 pubmed 出版商
Hwang J, Kim K, Oh H, Yoo G, Jeong M, Lee H, et al. TAZ links exercise to mitochondrial biogenesis via mitochondrial transcription factor A. Nat Commun. 2022;13:653 pubmed 出版商
Shen Y, Zhang H, Yao S, Su F, Wang H, Yin J, et al. Methionine oxidation of CLK4 promotes the metabolic switch and redox homeostasis in esophageal carcinoma via inhibiting MITF selective autophagy. Clin Transl Med. 2022;12:e719 pubmed 出版商
Drube J, Haider R, Matthees E, Reichel M, Zeiner J, Fritzwanker S, et al. GPCR kinase knockout cells reveal the impact of individual GRKs on arrestin binding and GPCR regulation. Nat Commun. 2022;13:540 pubmed 出版商
Prescott J, Balmanno K, Mitchell J, Okkenhaug H, Cook S. IKKα plays a major role in canonical NF-κB signalling in colorectal cells. Biochem J. 2022;479:305-325 pubmed 出版商
Bhattacharya A, Fushimi A, Yamashita N, Hagiwara M, Morimoto Y, Rajabi H, et al. MUC1-C Dictates JUN and BAF-Mediated Chromatin Remodeling at Enhancer Signatures in Cancer Stem Cells. Mol Cancer Res. 2022;20:556-567 pubmed 出版商
Kumar B, Adebayo A, Prasad M, Capitano M, Wang R, Bhat Nakshatri P, et al. Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity. Sci Adv. 2022;8:eabh3375 pubmed 出版商
Ishikawa M, Osaki M, Uno N, Ohira T, Kugoh H, Okada F. MTA1, a metastasis‑associated protein, in endothelial cells is an essential molecule for angiogenesis. Mol Med Rep. 2022;25: pubmed 出版商
Togami K, Chung S, Madan V, Booth C, Kenyon C, Cabal Hierro L, et al. Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis. Cancer Discov. 2022;12:522-541 pubmed 出版商
Huang Y, Tsai T, Chang C, Chang K, Ko P, Lai L. Indoxyl Sulfate Elevated Lnc-SLC15A1-1 Upregulating CXCL10/CXCL8 Expression in High-Glucose Endothelial Cells by Sponging MicroRNAs. Toxins (Basel). 2021;13: pubmed 出版商
Chen W, Ding Y, Liu D, Lu Z, Wang Y, Yuan Y. Kaposi's sarcoma-associated herpesvirus vFLIP promotes MEndT to generate hybrid M/E state for tumorigenesis. PLoS Pathog. 2021;17:e1009600 pubmed 出版商
Vajhøj C, Schmid B, Alik A, Melki R, Fog K, Holst B, et al. Establishment of a human induced pluripotent stem cell neuronal model for identification of modulators of A53T α-synuclein levels and aggregation. PLoS ONE. 2021;16:e0261536 pubmed 出版商
Yan Y, Zhou B, Lee Y, You S, Freeman M, Yang W. BoxCar and shotgun proteomic analyses reveal molecular networks regulated by UBR5 in prostate cancer. Proteomics. 2021;:e2100172 pubmed 出版商
Li K, Sun X, Li B, Yokota H. Conversion of Osteoclasts into Bone-Protective, Tumor-Suppressing Cells. Cancers (Basel). 2021;13: pubmed 出版商
Pasten C, Lozano M, Rocco J, Carrion F, Alvarado C, Liberona J, et al. Aminoguanidine Prevents the Oxidative Stress, Inhibiting Elements of Inflammation, Endothelial Activation, Mesenchymal Markers, and Confers a Renoprotective Effect in Renal Ischemia and Reperfusion Injury. Antioxidants (Basel). 2021;10: pubmed 出版商
Shi Y, Ye Z, Lu G, Yang N, Zhang J, Wang L, et al. Cholesterol-enriched membrane micro-domaindeficiency induces doxorubicin resistancevia promoting autophagy in breast cancer. Mol Ther Oncolytics. 2021;23:311-329 pubmed 出版商
Lin Y, Lin C, Ho E, Ke Y, Petridi S, Elliott C, et al. Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson's disease. elife. 2021;10: pubmed 出版商
Kim J, Jang G, Sim S, Park I, Kim K, Park C. SMARCA4 Depletion Induces Cisplatin Resistance by Activating YAP1-Mediated Epithelial-to-Mesenchymal Transition in Triple-Negative Breast Cancer. Cancers (Basel). 2021;13: pubmed 出版商
Greco S, Ayer S, Guiro K, Sinha G, Donnelly R, El Far M, et al. Restoration of aged hematopoietic cells by their young counterparts through instructive microvesicles release. Aging (Albany NY). 2021;13:23981-24016 pubmed 出版商
Tsai Y, Chen S, Peng S, Tsai Y, Chang Z, Chang V, et al. Upregulating sirtuin 6 ameliorates glycolysis, EMT and distant metastasis of pancreatic adenocarcinoma with krüppel-like factor 10 deficiency. Exp Mol Med. 2021;53:1623-1635 pubmed 出版商
Kang H, Eom H, Kim H, Myung K, Kwon H, Choi J. Thrap3 promotes R-loop resolution via interaction with methylated DDX5. Exp Mol Med. 2021;53:1602-1611 pubmed 出版商
Fisher M, Balinth S, Hwangbo Y, Wu C, Ballon C, Wilkinson J, et al. BRD4 Regulates Transcription Factor ΔNp63α to Drive a Cancer Stem Cell Phenotype in Squamous Cell Carcinomas. Cancer Res. 2021;81:6246-6258 pubmed 出版商
Shang X, Shi Y, He D, Wang L, Luo Q, Deng C, et al. ARID1A deficiency weakens BRG1-RAD21 interaction that jeopardizes chromatin compactness and drives liver cancer cell metastasis. Cell Death Dis. 2021;12:990 pubmed 出版商
Zhao S, Zhou L, Dicker D, Lev A, Zhang S, Ross E, et al. Anti-cancer efficacy including Rb-deficient tumors and VHL-independent HIF1α proteasomal destabilization by dual targeting of CDK1 or CDK4/6 and HSP90. Sci Rep. 2021;11:20871 pubmed 出版商
Hollenbach M, Sonnenberg S, Sommerer I, Lorenz J, Hoffmeister A. Glyoxalase-I Is Upregulated in Acute Cerulein-Induced Pancreatitis: A New Mechanism in Pancreatic Inflammation?. Antioxidants (Basel). 2021;10: pubmed 出版商
Wang Z, Ren S, Li Q, Royster A, Lin L, Liu S, et al. Hantaviruses use the endogenous host factor P58IPK to combat the PKR antiviral response. PLoS Pathog. 2021;17:e1010007 pubmed 出版商
Peng S, Chen X, Chen S, Zhang J, Wang C, Liu W, et al. Phase separation of Nur77 mediates celastrol-induced mitophagy by promoting the liquidity of p62/SQSTM1 condensates. Nat Commun. 2021;12:5989 pubmed 出版商
Shetty A, Bhosale S, Tripathi S, Buchacher T, Biradar R, Rasool O, et al. Interactome Networks of FOSL1 and FOSL2 in Human Th17 Cells. ACS Omega. 2021;6:24834-24847 pubmed 出版商
Liu X, Verma A, Garcia G, Ramage H, Lucas A, Myers R, et al. Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition. Proc Natl Acad Sci U S A. 2021;118: pubmed 出版商
Soto Faguás C, Sanchez Molina P, Saura C. Loss of presenilin function enhances tau phosphorylation and aggregation in mice. Acta Neuropathol Commun. 2021;9:162 pubmed 出版商
Huang Y, Cheng A, Tang H, Huang G, Cai L, Lin T, et al. USP7 facilitates SMAD3 autoregulation to repress cancer progression in p53-deficient lung cancer. Cell Death Dis. 2021;12:880 pubmed 出版商
Hahn F, Häge S, Herrmann A, Wangen C, Kicuntod J, Jungnickl D, et al. Methodological Development of a Multi-Readout Assay for the Assessment of Antiviral Drugs against SARS-CoV-2. Pathogens. 2021;10: pubmed 出版商
Lin H, Hsieh M, Wang C, Yu P, Lee M, Chen J. Anti-Atherosclerotic Effect of Gossypetin on Abnormal Vascular Smooth Muscle Cell Proliferation and Migration. Antioxidants (Basel). 2021;10: pubmed 出版商
Komata Y, Tsubota S, Sakamoto K, Ikematsu S, Kadomatsu K. Screening of novel Midkine binding protein by BioID2-based proximity labeling. Nagoya J Med Sci. 2021;83:495-508 pubmed 出版商
Kim G, Mo H, Liu H, Wu Z, Chen S, Zheng J, et al. A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons. elife. 2021;10: pubmed 出版商
Gustavsson N, Savchenko E, Klementieva O, Roybon L. The intracellular milieu of Parkinson's disease patient brain cells modulates alpha-synuclein protein aggregation. Acta Neuropathol Commun. 2021;9:153 pubmed 出版商
Roupakia E, Chavdoula E, Karpathiou G, Vatsellas G, Chatzopoulos D, Mela A, et al. Canonical NF-κB Promotes Lung Epithelial Cell Tumour Growth by Downregulating the Metastasis Suppressor CD82 and Enhancing Epithelial-to-Mesenchymal Cell Transition. Cancers (Basel). 2021;13: pubmed 出版商
Quambusch L, Depta L, Landel I, Lubeck M, Kirschner T, Nabert J, et al. Cellular model system to dissect the isoform-selectivity of Akt inhibitors. Nat Commun. 2021;12:5297 pubmed 出版商
Gudikote J, Cascone T, Poteete A, Sitthideatphaiboon P, Wu Q, Morikawa N, et al. Inhibition of nonsense-mediated decay rescues p53β/γ isoform expression and activates the p53 pathway in MDM2-overexpressing and select p53-mutant cancers. J Biol Chem. 2021;297:101163 pubmed 出版商
Chen Y, Chen C, Chien C, Su Y, Luo S, Li S. Overexpression of UTX promotes tumor progression in Oral tongue squamous cell carcinoma patients receiving surgical resection: a case control study. BMC Cancer. 2021;21:979 pubmed 出版商
Li H, Li T, Wang H, He X, Li Y, Wen S, et al. Diabetes Promotes Retinal Vascular Endothelial Cell Injury by Inducing CCN1 Expression. Front Cardiovasc Med. 2021;8:689318 pubmed 出版商
Tobacyk J, Kc G, Macmillan Crow L. Overexpression of MnSOD Protects against Cold Storage-Induced Mitochondrial Injury but Not against OMA1-Dependent OPA1 Proteolytic Processing in Rat Renal Proximal Tubular Cells. Antioxidants (Basel). 2021;10: pubmed 出版商
Kenny H, Hart P, Kordylewicz K, Lal M, Shen M, Kara B, et al. The Natural Product β-Escin Targets Cancer and Stromal Cells of the Tumor Microenvironment to Inhibit Ovarian Cancer Metastasis. Cancers (Basel). 2021;13: pubmed 出版商
Moreci R, Lechler T. KIF18B is a cell type-specific regulator of spindle orientation in the epidermis. Mol Biol Cell. 2021;32:ar29 pubmed 出版商
Yasuda K, Matsubara T, Shirakawa T, Kawamoto T, Kokabu S. Protein phosphatase 1 regulatory subunit 18 suppresses the transcriptional activity of NFATc1 via regulation of c-fos. Bone Rep. 2021;15:101114 pubmed 出版商
Liu S, Sun X, Li K, Zha R, Feng Y, Sano T, et al. Generation of the tumor-suppressive secretome from tumor cells. Theranostics. 2021;11:8517-8534 pubmed 出版商
Samson J, Derlipanska M, Zaheed O, Dean K. Molecular and cellular characterization of two patient-derived ductal carcinoma in situ (DCIS) cell lines, ETCC-006 and ETCC-010. BMC Cancer. 2021;21:790 pubmed 出版商
Ferrucci V, Kong D, Asadzadeh F, Marrone L, Boccia A, Siciliano R, et al. Long-chain polyphosphates impair SARS-CoV-2 infection and replication. Sci Signal. 2021;14: pubmed 出版商
Saura Esteller J, Sánchez Vera I, Núñez Vázquez S, Cosialls A, Gama Pérez P, Bhosale G, et al. Activation of the Integrated Stress Response and ER Stress Protect from Fluorizoline-Induced Apoptosis in HEK293T and U2OS Cell Lines. Int J Mol Sci. 2021;22: pubmed 出版商
Xu S, Wu X, Wang P, Cao S, Peng B, Xu X. ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability. iScience. 2021;24:102534 pubmed 出版商
Zhou L, Nho K, Haddad M, Cherepacha N, Tubeleviciute Aydin A, Tsai A, et al. Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration. Sci Rep. 2021;11:12695 pubmed 出版商
Ji Q, Zong X, Mao Y, Qian S. A heat shock-responsive lncRNA Heat acts as a HSF1-directed transcriptional brake via m6A modification. Proc Natl Acad Sci U S A. 2021;118: pubmed 出版商
Anderson M, Zhang Q, Rodriguez L, Hecquet C, Donawho C, Ansell P, et al. ABBV-176, a PRLR antibody drug conjugate with a potent DNA-damaging PBD cytotoxin and enhanced activity with PARP inhibition. BMC Cancer. 2021;21:681 pubmed 出版商
Baik S, Selvaraji S, Fann D, Poh L, Jo D, Herr D, et al. Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging. Aging (Albany NY). 2021;13:14651-14674 pubmed 出版商
Klaessens S, Stroobant V, Hoffmann D, Gyrd Hansen M, Pilotte L, Vigneron N, et al. Tryptophanemia is controlled by a tryptophan-sensing mechanism ubiquitinating tryptophan 2,3-dioxygenase. Proc Natl Acad Sci U S A. 2021;118: pubmed 出版商
Potteti H, Venkareddy L, Noone P, Ankireddy A, Tamatam C, Mehta D, et al. Nrf2 Regulates Anti-Inflammatory A20 Deubiquitinase Induction by LPS in Macrophages in Contextual Manner. Antioxidants (Basel). 2021;10: pubmed 出版商
Urdiciain A, Erausquin E, Zelaya M, Zazpe I, Lanciego J, Melendez B, et al. Silencing of Histone Deacetylase 6 Decreases Cellular Malignancy and Contributes to Primary Cilium Restoration, Epithelial-to-Mesenchymal Transition Reversion, and Autophagy Inhibition in Glioblastoma Cell Lines. Biology (Basel). 2021;10: pubmed 出版商
Tsao C, Baumann J, Huang S, Kindler D, Schroeter A, Kachappilly N, et al. Pericyte hypoxia-inducible factor-1 (HIF-1) drives blood-brain barrier disruption and impacts acute ischemic stroke outcome. Angiogenesis. 2021;24:823-842 pubmed 出版商
Larson Casey J, Gu L, Davis D, Cai G, Ding Q, He C, et al. Post-translational regulation of PGC-1α modulates fibrotic repair. FASEB J. 2021;35:e21675 pubmed 出版商
Cai C, Gu S, Yu Y, Zhu Y, Zhang H, Yuan B, et al. PRMT5 Enables Robust STAT3 Activation via Arginine Symmetric Dimethylation of SMAD7. Adv Sci (Weinh). 2021;8:2003047 pubmed 出版商
Yang X, Nanayakkara J, Claypool D, Saghafinia S, Wong J, Xu M, et al. A miR-375/YAP axis regulates neuroendocrine differentiation and tumorigenesis in lung carcinoid cells. Sci Rep. 2021;11:10455 pubmed 出版商
Bi Y, Chen X, Wei B, Wang L, Gong L, Li H, et al. DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells. Theranostics. 2021;11:6355-6369 pubmed 出版商
Du F, Yu Q, Yan S, Zhang Z, Vangavaragu J, Chen D, et al. Gain of PITRM1 peptidase in cortical neurons affords protection of mitochondrial and synaptic function in an advanced age mouse model of Alzheimer's disease. Aging Cell. 2021;20:e13368 pubmed 出版商
Gonzalez Perez A, Stempel M, Wyler E, Urban C, Piras A, Hennig T, et al. The Zinc Finger Antiviral Protein ZAP Restricts Human Cytomegalovirus and Selectively Binds and Destabilizes Viral UL4/UL5 Transcripts. MBio. 2021;12: pubmed 出版商
Cartaya A, Lutz H, Maiocchi S, Nalesnik M, Bahnson E. Delivery of Cinnamic Aldehyde Antioxidant Response Activating nanoParticles (ARAPas) for Vascular Applications. Antioxidants (Basel). 2021;10: pubmed 出版商
Shan W, Zhou L, Liu L, Lin D, Yu Q. Polycomb group protein Bmi1 is required for the neuronal differentiation of mouse induced pluripotent stem cells. Exp Ther Med. 2021;21:619 pubmed 出版商
García Escudero V, Ruiz Gabarre D, Gargini R, Perez M, Garcia E, Cuadros R, et al. A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer's disease. Acta Neuropathol. 2021;142:159-177 pubmed 出版商
Pinto Bravo P, Rebordão M, Amaral A, Fernandes C, Galvão A, Silva E, et al. Microvascularization and Expression of Fibroblast Growth Factor and Vascular Endothelial Growth Factor and Their Receptors in the Mare Oviduct. Animals (Basel). 2021;11: pubmed 出版商
Sánchez Infantes D, Nus M, Navas Madroñal M, Fite J, Perez B, Barros Membrilla A, et al. Oxidative Stress and Inflammatory Markers in Abdominal Aortic Aneurysm. Antioxidants (Basel). 2021;10: pubmed 出版商
Wang W, Han R, He H, Li J, Chen S, Gu Y, et al. Administration of quercetin improves mitochondria quality control and protects the neurons in 6-OHDA-lesioned Parkinson's disease models. Aging (Albany NY). 2021;13:11738-11751 pubmed 出版商
Inoue D, Polaski J, Taylor J, Castel P, Chen S, Kobayashi S, et al. Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition. Nat Genet. 2021;53:707-718 pubmed 出版商
Varona S, Puertas L, Galán M, Orriols M, Cañes L, Aguiló S, et al. Rolipram Prevents the Formation of Abdominal Aortic Aneurysm (AAA) in Mice: PDE4B as a Target in AAA. Antioxidants (Basel). 2021;10: pubmed 出版商
Actis C, Muzio G, Autelli R. Autophagy Triggers Tamoxifen Resistance in Human Breast Cancer Cells by Preventing Drug-Induced Lysosomal Damage. Cancers (Basel). 2021;13: pubmed 出版商
Vo D, Engler A, Stoimenovski D, Hartig R, Kaehne T, Kalinski T, et al. Interactome Mapping of eIF3A in a Colon Cancer and an Immortalized Embryonic Cell Line Using Proximity-Dependent Biotin Identification. Cancers (Basel). 2021;13: pubmed 出版商
Li D, Tang L, Liu B, Xu S, Jin M, Bo W. RIPK2 is an unfavorable prognosis marker and a potential therapeutic target in human kidney renal clear cell carcinoma. Aging (Albany NY). 2021;13:10450-10467 pubmed 出版商
Bosa L, Batura V, Colavito D, Fiedler K, Gaio P, Guo C, et al. Novel CARMIL2 loss-of-function variants are associated with pediatric inflammatory bowel disease. Sci Rep. 2021;11:5945 pubmed 出版商
Arcones A, Vila Bedmar R, Mirasierra M, Cruces Sande M, Vallejo M, Jones B, et al. GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo. BMC Biol. 2021;19:40 pubmed 出版商
Ferreira N, Gonçalves N, Jan A, Jensen N, van der Laan A, Mohseni S, et al. Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain. Acta Neuropathol Commun. 2021;9:31 pubmed 出版商
Spits M, Heesterbeek I, Voortman L, Akkermans J, Wijdeven R, Cabukusta B, et al. Mobile late endosomes modulate peripheral endoplasmic reticulum network architecture. EMBO Rep. 2021;:e50815 pubmed 出版商
Kushwaha R, Sinha A, Makarava N, Molesworth K, Baskakov I. Non-cell autonomous astrocyte-mediated neuronal toxicity in prion diseases. Acta Neuropathol Commun. 2021;9:22 pubmed 出版商
Cheah P, Prabhakar S, Yellen D, Beauchamp R, Zhang X, Kasamatsu S, et al. Gene therapy for tuberous sclerosis complex type 2 in a mouse model by delivery of AAV9 encoding a condensed form of tuberin. Sci Adv. 2021;7: pubmed 出版商
Birkisdóttir M, Jaarsma D, Brandt R, Barnhoorn S, van Vliet N, Imholz S, et al. Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice. Aging Cell. 2021;20:e13302 pubmed 出版商
Truman J, Ruiz C, Trayssac M, Mao C, Hannun Y, Obeid L. Sphingosine kinase 1 downregulation is required for adaptation to serine deprivation. FASEB J. 2021;35:e21284 pubmed 出版商
Dong C, An L, Yu C, Huen M. A DYRK1B-dependent pathway suppresses rDNA transcription in response to DNA damage. Nucleic Acids Res. 2021;: pubmed 出版商
Rey F, Ottolenghi S, Giallongo T, Balsari A, Martinelli C, Rey R, et al. Mitochondrial Metabolism as Target of the Neuroprotective Role of Erythropoietin in Parkinson's Disease. Antioxidants (Basel). 2021;10: pubmed 出版商
Feng Y, Liu S, Zha R, Sun X, Li K, ROBLING A, et al. Mechanical Loading-Driven Tumor Suppression Is Mediated by Lrp5-Dependent and Independent Mechanisms. Cancers (Basel). 2021;13: pubmed 出版商
Shin H, Jeong E, Lee J, An H, Jang H, Ahn Y, et al. Lipocalin-2 Deficiency Reduces Oxidative Stress and Neuroinflammation and Results in Attenuation of Kainic Acid-Induced Hippocampal Cell Death. Antioxidants (Basel). 2021;10: pubmed 出版商
Webb L, Fra Bido S, Innocentin S, Matheson L, Attaf N, Bignon A, et al. Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ. Aging Cell. 2021;20:e13295 pubmed 出版商
Agrawal P, Blinka S, Pulakanti K, Reimer M, Stelloh C, Meyer A, et al. Genome editing demonstrates that the -5 kb Nanog enhancer regulates Nanog expression by modulating RNAPII initiation and/or recruitment. J Biol Chem. 2021;296:100189 pubmed 出版商
Pimenova A, Herbinet M, Gupta I, Machlovi S, Bowles K, Marcora E, et al. Alzheimer's-associated PU.1 expression levels regulate microglial inflammatory response. Neurobiol Dis. 2021;148:105217 pubmed 出版商
Vara D, Mailer R, Tarafdar A, Wolska N, Heestermans M, Konrath S, et al. NADPH Oxidases Are Required for Full Platelet Activation In Vitro and Thrombosis In Vivo but Dispensable for Plasma Coagulation and Hemostasis. Arterioscler Thromb Vasc Biol. 2021;41:683-697 pubmed 出版商
Abe S, Iwasaki M, Habata S, Mariya T, Tamate M, Matsuura M, et al. ERα increases endometrial cancer cell resistance to cisplatin via upregulation of BAG3. Oncol Lett. 2021;21:20 pubmed 出版商
Wang J, Lin Z, Li L, Zhang S, Li W, Liu W, et al. SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1. J Biol Chem. 2021;296:100032 pubmed 出版商
Radhakrishnan R, Kowluru R. Long Noncoding RNA MALAT1 and Regulation of the Antioxidant Defense System in Diabetic Retinopathy. Diabetes. 2021;70:227-239 pubmed 出版商
Wei F, Jing H, Wei M, Liu L, Wu J, Wang M, et al. Ring finger protein 2 promotes colorectal cancer progression by suppressing early growth response 1. Aging (Albany NY). 2020;12:26199-26220 pubmed 出版商
Yuan X, Piao L, Wang L, Han X, Tong L, Shao S, et al. Erythrocyte membrane protein band 4.1-like 3 inhibits osteosarcoma cell invasion through regulation of Snai1-induced epithelial-to-mesenchymal transition. Aging (Albany NY). 2020;13:1947-1961 pubmed 出版商
Wasson C, Ross R, Wells R, Corinaldesi C, Georgiou I, Riobo Del Galdo N, et al. Long non-coding RNA HOTAIR induces GLI2 expression through Notch signalling in systemic sclerosis dermal fibroblasts. Arthritis Res Ther. 2020;22:286 pubmed 出版商
Yu J, Ju J, Musacchio N, Mathias T, Vitolo M. Long Noncoding RNA DANCR Activates Wnt/β-Catenin Signaling through MiR-216a Inhibition in Non-Small Cell Lung Cancer. Biomolecules. 2020;10: pubmed 出版商
Vallese F, Catoni C, Cieri D, Barazzuol L, Ramírez O, Calore V, et al. An expanded palette of improved SPLICS reporters detects multiple organelle contacts in vitro and in vivo. Nat Commun. 2020;11:6069 pubmed 出版商
Zhou L, Huntington K, Zhang S, Carlsen L, So E, Parker C, et al. MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection. Oncotarget. 2020;11:4201-4223 pubmed 出版商
Nakajima K, Miranda A, Craig D, Shekhtman T, Kmoch S, Bleyer A, et al. Ntrk1 mutation co-segregating with bipolar disorder and inherited kidney disease in a multiplex family causes defects in neuronal growth and depression-like behavior in mice. Transl Psychiatry. 2020;10:407 pubmed 出版商
Gutiérrez Miranda B, Gallardo I, Melliou E, Cabero I, Alvarez Y, Magiatis P, et al. Oleacein Attenuates the Pathogenesis of Experimental Autoimmune Encephalomyelitis through Both Antioxidant and Anti-Inflammatory Effects. Antioxidants (Basel). 2020;9: pubmed 出版商
BORRAS T, Cowley D, Asokan P, Pandya K. Generation of a Matrix Gla (Mgp) floxed mouse, followed by conditional knockout, uncovers a new Mgp function in the eye. Sci Rep. 2020;10:18583 pubmed 出版商
Ruiz Rodado V, Lita A, Dowdy T, Celiku O, Saldana A, Wang H, et al. Metabolic plasticity of IDH1-mutant glioma cell lines is responsible for low sensitivity to glutaminase inhibition. Cancer Metab. 2020;8:23 pubmed 出版商
Schuster S, Heuten E, Velic A, Admard J, Synofzik M, Ossowski S, et al. CHIP mutations affect the heat shock response differently in human fibroblasts and iPSC-derived neurons. Dis Model Mech. 2020;13: pubmed 出版商
Simões I, Karkucinska Wieckowska A, Janikiewicz J, Szymanska S, Pronicki M, Dobrzyn P, et al. Western Diet Causes Obesity-Induced Nonalcoholic Fatty Liver Disease Development by Differentially Compromising the Autophagic Response. Antioxidants (Basel). 2020;9: pubmed 出版商
Mandl M, Ritthammer H, Ejaz A, Wagner S, Hatzmann F, Baumgarten S, et al. CRISPR/Cas9-mediated gene knockout in human adipose stem/progenitor cells. Adipocyte. 2020;9:626-635 pubmed 出版商
Ide S, Imai R, Ochi H, Maeshima K. Transcriptional suppression of ribosomal DNA with phase separation. Sci Adv. 2020;6: pubmed 出版商
Hollinshead K, Parker S, Eapen V, Encarnación Rosado J, Sohn A, Oncu T, et al. Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer. Cell Rep. 2020;33:108231 pubmed 出版商
Blankenbach K, Claas R, Aster N, Spohner A, Trautmann S, Ferreirós N, et al. Dissecting Gq/11-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1. Cells. 2020;9: pubmed 出版商
Muniraj N, Siddharth S, Shriver M, Nagalingam A, Parida S, Woo J, et al. Induction of STK11-dependent cytoprotective autophagy in breast cancer cells upon honokiol treatment. Cell Death Discov. 2020;6:81 pubmed 出版商
Talwar D, Messens J, Dick T. A role for annexin A2 in scaffolding the peroxiredoxin 2-STAT3 redox relay complex. Nat Commun. 2020;11:4512 pubmed 出版商
Kooij R, Liu S, Sapmaz A, Xin B, Janssen G, van Veelen P, et al. Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos. J Am Chem Soc. 2020;142:16825-16841 pubmed 出版商
He B, Moreau R. R-α-Lipoic Acid and 4-Phenylbutyric Acid Have Distinct Hypolipidemic Mechanisms in Hepatic Cells. Biomedicines. 2020;8: pubmed 出版商
Fan J, You L, Wang W, Huang W, Chu C, Chi Y, et al. Lamin A-mediated nuclear lamina integrity is required for proper ciliogenesis. EMBO Rep. 2020;21:e49680 pubmed 出版商
Cendrowski J, Kaczmarek M, Mazur M, Kuzmicz Kowalska K, Jastrzębski K, Brewińska Olchowik M, et al. Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells. elife. 2020;9: pubmed 出版商
Yi J, Kim T, Pak J, Chung J. Protective Effects of Glucose-Related Protein 78 and 94 on Cisplatin-Mediated Ototoxicity. Antioxidants (Basel). 2020;9: pubmed 出版商
Kaji S, Maki T, Ueda J, Ishimoto T, Inoue Y, Yasuda K, et al. BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy. Acta Neuropathol Commun. 2020;8:120 pubmed 出版商
Bayraktar G, Yuanxiang P, Confettura A, Gomes G, Raza S, Stork O, et al. Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus. Neuropsychopharmacology. 2020;45:2120-2130 pubmed 出版商
Guo Y, Gu D, Huang T, Cao L, Zhu X, Zhou Y, et al. Essential role of Salmonella Enteritidis DNA adenine methylase in modulating inflammasome activation. BMC Microbiol. 2020;20:226 pubmed 出版商
Trümper V, Wittig I, Heidler J, Richter F, Brüne B, von Knethen A. Redox Regulation of PPARγ in Polarized Macrophages. PPAR Res. 2020;2020:8253831 pubmed 出版商
Feldker N, Ferrazzi F, Schuhwerk H, Widholz S, Guenther K, Frisch I, et al. Genome-wide cooperation of EMT transcription factor ZEB1 with YAP and AP-1 in breast cancer. EMBO J. 2020;:e103209 pubmed 出版商
Qi Y, Liu J, Chao J, Greer P, Li S. PTEN dephosphorylates Abi1 to promote epithelial morphogenesis. J Cell Biol. 2020;219: pubmed 出版商
Park C, Song M, Park J, Youn H, Chung J, Jeong J, et al. Conjugation of arginylglycylaspartic acid to human serum albumin decreases the tumor-targeting effect of albumin by hindering its secreted protein acidic and rich in cysteine-mediated accumulation in tumors. Am J Transl Res. 2020;12:2488-2498 pubmed
Guarino Almeida E, Renaudin X, Venkitaraman A. A kinase-independent function for AURORA-A in replisome assembly during DNA replication initiation. Nucleic Acids Res. 2020;: pubmed 出版商
Park H, Gholam Zadeh M, Suh J, Choi H. Dauricine Protects from LPS-Induced Bone Loss via the ROS/PP2A/NF-κB Axis in Osteoclasts. Antioxidants (Basel). 2020;9: pubmed 出版商
Seo G, Han H, Vargas R, Yang B, Li X, Wang W. MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation. Cell Rep. 2020;32:107860 pubmed 出版商
Aravani D, Foote K, Figg N, Finigan A, Uryga A, Clarke M, et al. Cytokine regulation of apoptosis-induced apoptosis and apoptosis-induced cell proliferation in vascular smooth muscle cells. Apoptosis. 2020;25:648-662 pubmed 出版商
Kim Y, Won Y, Lim B, Min T, Kim Y, Lee I. Neuroprotective effects of magnesium L-threonate in a hypoxic zebrafish model. BMC Neurosci. 2020;21:29 pubmed 出版商
Geng X, Yanagida K, Akwii R, Choi D, Chen L, Ho Y, et al. S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling. JCI Insight. 2020;5: pubmed 出版商
Matson C, Choi S, Livak F, Zhao B, Mitra A, Love P, et al. CD5 dynamically calibrates basal NF-κB signaling in T cells during thymic development and peripheral activation. Proc Natl Acad Sci U S A. 2020;117:14342-14353 pubmed 出版商
Ando K, Ndjim M, Turbant S, Fontaine G, Pregoni G, Dauphinot L, et al. The lipid phosphatase Synaptojanin 1 undergoes a significant alteration in expression and solubility and is associated with brain lesions in Alzheimer's disease. Acta Neuropathol Commun. 2020;8:79 pubmed 出版商
Martello A, Lauriola A, Mellis D, Parish E, Dawson J, Imrie L, et al. Trichoplein binds PCM1 and controls endothelial cell function by regulating autophagy. EMBO Rep. 2020;21:e48192 pubmed 出版商
Albers E, Avram A, Sbroggiò M, Fernandez Capetillo O, López Contreras A. Supraphysiological protection from replication stress does not extend mammalian lifespan. Aging (Albany NY). 2020;12:5612-5624 pubmed 出版商
Palrasu M, Zaika E, El Rifai W, Garcia Buitrago M, Piazuelo M, Wilson K, et al. Bacterial CagA protein compromises tumor suppressor mechanisms in gastric epithelial cells. J Clin Invest. 2020;130:2422-2434 pubmed 出版商
Fan L, Xu S, Zhang F, Cui X, Fazli L, Gleave M, et al. Histone demethylase JMJD1A promotes expression of DNA repair factors and radio-resistance of prostate cancer cells. Cell Death Dis. 2020;11:214 pubmed 出版商
Liu Y, Lu Y, Li A, Celiku O, Han S, Qian M, et al. mTORC2/Rac1 Pathway Predisposes Cancer Aggressiveness in IDH1-Mutated Glioma. Cancers (Basel). 2020;12: pubmed 出版商
Costa A, Sousa S, Pinto Costa R, Mateus J, Lopes C, Costa A, et al. The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction. elife. 2020;9: pubmed 出版商
Tsai M, Huang C, Wei Y, Liu T, Lin M, Yi L, et al. Combined Chibby and β-Catenin Predicts Clinical Outcomes in Patients with Hepatocellular Carcinoma. Int J Mol Sci. 2020;21: pubmed 出版商
Dubois M, Meller A, Samandi S, Brunelle M, Frion J, Brunet M, et al. UBB pseudogene 4 encodes functional ubiquitin variants. Nat Commun. 2020;11:1306 pubmed 出版商
Nachtigal A, Milenkovic A, Brandl C, Schulz H, Duerr L, Lang G, et al. Mutation-Dependent Pathomechanisms Determine the Phenotype in the Bestrophinopathies. Int J Mol Sci. 2020;21: pubmed 出版商
van Gastel N, Stegen S, Eelen G, Schoors S, Carlier A, Daniëls V, et al. Lipid availability determines fate of skeletal progenitor cells via SOX9. Nature. 2020;579:111-117 pubmed 出版商
Kosuge Y, Kaneko E, Nango H, Miyagishi H, Ishige K, Ito Y. Bidens pilosa Extract Administered after Symptom Onset Attenuates Glial Activation, Improves Motor Performance, and Prolongs Survival in a Mouse Model of Amyotrophic Lateral Sclerosis. Oxid Med Cell Longev. 2020;2020:1020673 pubmed 出版商
Chojnowski A, Ong P, Foo M, Liebl D, Hor L, Stewart C, et al. Heterochromatin loss as a determinant of progerin-induced DNA damage in Hutchinson-Gilford Progeria. Aging Cell. 2020;19:e13108 pubmed 出版商
Odintsova E, Mohammed F, Trieber C, Rodriguez Zamora P, Al Jassar C, Huang T, et al. Binding of the periplakin linker requires vimentin acidic residues D176 and E187. Commun Biol. 2020;3:83 pubmed 出版商
Luciani A, Schumann A, Berquez M, Chen Z, Nieri D, Failli M, et al. Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nat Commun. 2020;11:970 pubmed 出版商
Marycz K, Sobierajska P, Roecken M, Kornicka Garbowska K, Kepska M, Idczak R, et al. Iron oxides nanoparticles (IOs) exposed to magnetic field promote expression of osteogenic markers in osteoblasts through integrin alpha-3 (INTa-3) activation, inhibits osteoclasts activity and exerts anti-inflammatory action. J Nanobiotechnology. 2020;18:33 pubmed 出版商
Zhang Y, Yang K, Yang J, Lao Y, Deng L, Deng G, et al. SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes. Cell Rep. 2020;30:1951-1963.e4 pubmed 出版商
Sethi N, Kikuchi O, Duronio G, Stachler M, McFarland J, Ferrer Luna R, et al. Early TP53 alterations engage environmental exposures to promote gastric premalignancy in an integrative mouse model. Nat Genet. 2020;52:219-230 pubmed 出版商
Shu J, Cui D, Ma Y, Xiong X, Sun Y, Zhao Y. SCFβ-TrCP-mediated degradation of TOP2β promotes cancer cell survival in response to chemotherapeutic drugs targeting topoisomerase II. Oncogenesis. 2020;9:8 pubmed 出版商
Bera R, Chiu M, Huang Y, Huang G, Lee Y, Shih L. DNMT3A mutants provide proliferating advantage with augmentation of self-renewal activity in the pathogenesis of AML in KMT2A-PTD-positive leukemic cells. Oncogenesis. 2020;9:7 pubmed 出版商
Laperle A, Sances S, Yucer N, Dardov V, García V, Ho R, et al. iPSC modeling of young-onset Parkinson's disease reveals a molecular signature of disease and novel therapeutic candidates. Nat Med. 2020;26:289-299 pubmed 出版商
McGinn O, Ward A, Fettig L, Riley D, Ivie J, Paul K, et al. Cytokeratin 5 alters β-catenin dynamics in breast cancer cells. Oncogene. 2020;39:2478-2492 pubmed 出版商
Li C, He X, Huang Z, Han L, Wu X, Li L, et al. Melatonin ameliorates the advanced maternal age-associated meiotic defects in oocytes through the SIRT2-dependent H4K16 deacetylation pathway. Aging (Albany NY). 2020;12:1610-1623 pubmed 出版商
Wu J, Tsai H, Hsiao Y, Wu J, Wu C, Tai M. Topical MTII Therapy Suppresses Melanoma Through PTEN Upregulation and Cyclooxygenase II Inhibition. Int J Mol Sci. 2020;21: pubmed 出版商
Wright W, Chenge J, Wang J, Girvan H, Yang L, Chai S, et al. Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5. J Med Chem. 2020;63:1415-1433 pubmed 出版商
Cotzomi Ortega I, Rosas Cruz A, Ramírez Ramírez D, Reyes Leyva J, Rodriguez Sosa M, Aguilar Alonso P, et al. Autophagy Inhibition Induces the Secretion of Macrophage Migration Inhibitory Factor (MIF) with Autocrine and Paracrine Effects on the Promotion of Malignancy in Breast Cancer. Biology (Basel). 2020;9: pubmed 出版商
Klee K, Storti F, Maggi J, Todorova V, Karademir D, Berger W, et al. The Expression of Decidual Protein Induced by Progesterone (DEPP) is Controlled by Three Distal Consensus Hypoxia Responsive Element (HRE) in Hypoxic Retinal Epithelial Cells. Genes (Basel). 2020;11: pubmed 出版商
Kang Y, Hsu W, Ou C, Tai H, Hsu H, Yeh K, et al. Metformin Mitigates Nickel-Elicited Angiopoietin-Like Protein 4 Expression via HIF-1α for Lung Tumorigenesis. Int J Mol Sci. 2020;21: pubmed 出版商
He L, Liu Y, Lai W, Tian H, Chen L, Xie L, et al. DNA sensors, crucial receptors to resist pathogens, are deregulated in colorectal cancer and associated with initiation and progression of the disease. J Cancer. 2020;11:893-905 pubmed 出版商
Poddar I, Callahan P, Hernandez C, Pillai A, Yang X, Bartlett M, et al. Chronic oral treatment with risperidone impairs recognition memory and alters brain-derived neurotrophic factor and related signaling molecules in rats. Pharmacol Biochem Behav. 2020;189:172853 pubmed 出版商
Goya M, Xue F, Sampedro Torres Quevedo C, Arnaouteli S, Riquelme Dominguez L, Romanowski A, et al. Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans. Cell Rep. 2020;30:367-380.e7 pubmed 出版商
Miyajima C, Kawarada Y, Inoue Y, Suzuki C, Mitamura K, Morishita D, et al. Transcriptional Coactivator TAZ Negatively Regulates Tumor Suppressor p53 Activity and Cellular Senescence. Cells. 2020;9: pubmed 出版商
Riis S, Murray J, O Connor R. IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β-Nrf2-BNIP3 Pathway. Cells. 2020;9: pubmed 出版商
Vogt D, Zaver S, Ranjan A, DiMaio T, Gounder A, Smith J, et al. STING is dispensable during KSHV infection of primary endothelial cells. Virology. 2020;540:150-159 pubmed 出版商
Prieto I, Alarcón C, Garcia Gomez R, Berdun R, Urgel T, Portero M, et al. Metabolic adaptations in spontaneously immortalized PGC-1α knock-out mouse embryonic fibroblasts increase their oncogenic potential. Redox Biol. 2020;29:101396 pubmed 出版商
Benny M, Hernández D, Sharma M, Yousefi K, Kulandavelu S, Batlahally S, et al. Neonatal hyperoxia exposure induces aortic biomechanical alterations and cardiac dysfunction in juvenile rats. Physiol Rep. 2020;8:e14334 pubmed 出版商
Chen W, Li Y, Hsu C, Niu C, Pen W, Cheng K, et al. Connective tissue growth factor in hepatocytes is elevated by carbon tetrachloride via STAT3 activation. Mol Med Rep. 2020;21:1390-1398 pubmed 出版商
Pirozzi C, Lama A, Annunziata C, Cavaliere G, De Caro C, Citraro R, et al. Butyrate prevents valproate-induced liver injury: In vitro and in vivo evidence. FASEB J. 2020;34:676-690 pubmed 出版商
Matsuhisa K, Saito A, Cai L, Kaneko M, Okamoto T, Sakaue F, et al. Production of BBF2H7-derived small peptide fragments via endoplasmic reticulum stress-dependent regulated intramembrane proteolysis. FASEB J. 2020;34:865-880 pubmed 出版商
Wu D, Dasgupta A, Chen K, Neuber Hess M, Patel J, Hurst T, et al. Identification of novel dynamin-related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia-reperfusion injury. FASEB J. 2020;34:1447-1464 pubmed 出版商
Tibaldi E, Brocca A, Sticca A, Gola E, Pizzi M, Bordin L, et al. Fam20C-mediated phosphorylation of osteopontin is critical for its secretion but dispensable for its action as a cytokine in the activation of hepatic stellate cells in liver fibrogenesis. FASEB J. 2020;34:1122-1135 pubmed 出版商
Kasahara T, Kubota Sakashita M, Nagatsuka Y, Hirabayashi Y, Hanasaka T, Tohyama K, et al. Cardiolipin is essential for early embryonic viability and mitochondrial integrity of neurons in mammals. FASEB J. 2020;34:1465-1480 pubmed 出版商
Affronti H, Rowsam A, Pellerite A, Rosario S, Long M, Jacobi J, et al. Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy. Nat Commun. 2020;11:52 pubmed 出版商
Zhao E, Shen Y, Amir M, Farris A, Czaja M. Stathmin 1 Induces Murine Hepatocyte Proliferation and Increased Liver Mass. Hepatol Commun. 2020;4:38-49 pubmed 出版商
Komarynets O, Chassot A, Bernabeu E, Czogalla J, Roth I, Liaudet N, et al. Aldosterone controls primary cilium length and cell size in renal collecting duct principal cells. FASEB J. 2020;34:2625-2640 pubmed 出版商
Piers T, Cosker K, Mallach A, Johnson G, Guerreiro R, Hardy J, et al. A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC-derived microglia. FASEB J. 2020;34:2436-2450 pubmed 出版商
Ferrari A, Longo R, Peri C, Coppi L, Caruso D, Mai A, et al. Inhibition of class I HDACs imprints adipogenesis toward oxidative and brown-like phenotype. Biochim Biophys Acta Mol Cell Biol Lipids. 2020;1865:158594 pubmed 出版商
Bibbo S, Lamolinara A, Capone E, Purgato S, Tsakaneli A, Panella V, et al. Repurposing a psychoactive drug for children with cancer: p27Kip1-dependent inhibition of metastatic neuroblastomas by Prozac. Oncogenesis. 2020;9:3 pubmed 出版商
Ollauri Ibáñez C, Núñez Gómez E, Egido Turrión C, Silva Sousa L, Diaz Rodriguez E, Rodriguez Barbero A, et al. Continuous endoglin (CD105) overexpression disrupts angiogenesis and facilitates tumor cell metastasis. Angiogenesis. 2020;23:231-247 pubmed 出版商
Zhang X, Liu P, Shang Y, Kerndl H, Kumstel S, Gong P, et al. Metformin and LW6 impairs pancreatic cancer cells and reduces nuclear localization of YAP1. J Cancer. 2020;11:479-487 pubmed 出版商
Suwanmanee G, Yosudjai J, Phimsen S, Wongkham S, Jirawatnotai S, Kaewkong W. Upregulation of AGR2vH facilitates cholangiocarcinoma cell survival under endoplasmic reticulum stress via the activation of the unfolded protein response pathway. Int J Mol Med. 2020;45:669-677 pubmed 出版商
Chen Y, Lu H, Lo C, Hsiao C, Li S. NOX4 overexpression is a poor prognostic factor in patients undergoing curative esophagectomy for esophageal squamous cell carcinoma. Surgery. 2020;167:620-627 pubmed 出版商
Kline K, Lian H, Zhong X, Luo X, Winston J, Cong Y, et al. Neonatal Injury Increases Gut Permeability by Epigenetically Suppressing E-Cadherin in Adulthood. J Immunol. 2020;204:980-989 pubmed 出版商
Hu T, Zhang N, Ruan Y, Tan Q, Wang J. Hydrogen sulfide modulates high glucose-induced NLRP3 inflammasome activation in 3T3-L1 adipocytes. Exp Ther Med. 2020;19:771-776 pubmed 出版商
Lin W, Bwayi M, Wu J, Li Y, Chai S, Huber A, et al. CITCO Directly Binds to and Activates Human Pregnane X Receptor. Mol Pharmacol. 2020;97:180-190 pubmed 出版商
Cabrera Cruz H, Oróstica L, Plaza Parrochia F, Torres Pinto I, Romero C, Vega M. The insulin-sensitizing mechanism of myo-inositol is associated with AMPK activation and GLUT-4 expression in human endometrial cells exposed to a PCOS environment. Am J Physiol Endocrinol Metab. 2020;318:E237-E248 pubmed 出版商
Hong J, Moon J, Park S. Human prion protein-mediated calcineurin activation induces neuron cell death via AMPK and autophagy pathway. Int J Biochem Cell Biol. 2020;119:105680 pubmed 出版商
Matsubara T, Yaginuma T, Addison W, Fujita Y, Watanabe K, Yoshioka I, et al. Plectin stabilizes microtubules during osteoclastic bone resorption by acting as a scaffold for Src and Pyk2. Bone. 2020;132:115209 pubmed 出版商
Seo B, Jeon K, Moon S, Lee K, Kim W, Jeong H, et al. Roseburia spp. Abundance Associates with Alcohol Consumption in Humans and Its Administration Ameliorates Alcoholic Fatty Liver in Mice. Cell Host Microbe. 2020;27:25-40.e6 pubmed 出版商
Fujii S, Tajiri Y, Hasegawa K, Matsumoto S, Yoshimoto R, Wada H, et al. The TRPV4-AKT axis promotes oral squamous cell carcinoma cell proliferation via CaMKII activation. Lab Invest. 2020;100:311-323 pubmed 出版商
Zhao L, Zhao J, Gao R, Tian Y, Zhang Y, Tang W, et al. Intrabody against prolyl hydroxylase 2 ameliorates acetaminophen-induced acute liver injury in mice via concomitant promotion of angiogenesis and redox homeostasis. Biomed Pharmacother. 2020;123:109783 pubmed 出版商
Kubra K, Uddin M, Akhter M, Barabutis N. Hsp90 inhibitors induce the unfolded protein response in bovine and mice lung cells. Cell Signal. 2020;67:109500 pubmed 出版商
Wang W, Wang J, Lin W, Kao C, Hung M, Teng Y, et al. Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis. Aging Cell. 2020;19:e13090 pubmed 出版商
Qu C, Yan C, Cao W, Li F, Qu Y, Guan K, et al. miR-128-3p contributes to mitochondrial dysfunction and induces apoptosis in glioma cells via targeting pyruvate dehydrogenase kinase 1. IUBMB Life. 2020;72:465-475 pubmed 出版商
Fan Q, He W, Gayen M, Benoit M, Luo X, Hu X, et al. Activated CX3CL1/Smad2 Signals Prevent Neuronal Loss and Alzheimer's Tau Pathology-Mediated Cognitive Dysfunction. J Neurosci. 2020;40:1133-1144 pubmed 出版商
Zhang J, Jazii F, Haghighi M, Alvares D, Liu L, Khosraviani N, et al. miR-130b is a potent stimulator of hepatic very-low-density lipoprotein assembly and secretion via marked induction of microsomal triglyceride transfer protein. Am J Physiol Endocrinol Metab. 2020;318:E262-E275 pubmed 出版商
Ross N, Lohmann F, Carbonneau S, Fazal A, Weihofen W, Gleim S, et al. CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma. Nat Chem Biol. 2020;16:50-59 pubmed 出版商
Kondrikov D, Elmansi A, Bragg R, Mobley T, Barrett T, Eisa N, et al. Kynurenine inhibits autophagy and promotes senescence in aged bone marrow mesenchymal stem cells through the aryl hydrocarbon receptor pathway. Exp Gerontol. 2020;130:110805 pubmed 出版商
Hoffmann D, Dvorakova T, Stroobant V, Bouzin C, Daumerie A, Solvay M, et al. Tryptophan 2,3-Dioxygenase Expression Identified in Human Hepatocellular Carcinoma Cells and in Intratumoral Pericytes of Most Cancers. Cancer Immunol Res. 2020;8:19-31 pubmed 出版商
Sah J, Hao N, Han X, Tran T, McCarthy S, Oh Y, et al. Ectonucleotide pyrophosphatase 2 (ENPP2) plays a crucial role in myogenic differentiation through the regulation by WNT/β-Catenin signaling. Int J Biochem Cell Biol. 2020;118:105661 pubmed 出版商
Mahajan S, Mellins E, Faccio R. Diacylglycerol Kinase ζ Regulates Macrophage Responses in Juvenile Arthritis and Cytokine Storm Syndrome Mouse Models. J Immunol. 2020;204:137-146 pubmed 出版商
Ylitalo E, Thysell E, Thellenberg Karlsson C, Lundholm M, Widmark A, Bergh A, et al. Marked response to cabazitaxel in prostate cancer xenografts expressing androgen receptor variant 7 and reversion of acquired resistance by anti-androgens. Prostate. 2020;80:214-224 pubmed 出版商
Oshima M, Pechberty S, Bellini L, Gopel S, Campana M, Rouch C, et al. Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity. Diabetologia. 2020;63:395-409 pubmed 出版商
Yang C, McDermot D, Pasricha S, Brown A, Bedoui S, Lenz L, et al. IFNγ receptor down-regulation facilitates Legionella survival in alveolar macrophages. J Leukoc Biol. 2020;107:273-284 pubmed 出版商
Cho H, Yadav A, Do Y, Heo M, Bishop Bailey D, Lee J, et al. Anti‑survival and pro‑apoptotic effects of meridianin C derivatives on MV4‑11 human acute myeloid leukemia cells. Int J Oncol. 2020;56:368-378 pubmed 出版商
Głombik K, Detka J, Goralska J, Kurek A, Solnica B, Budziszewska B. Brain Metabolic Alterations in Rats Showing Depression-Like and Obesity Phenotypes. Neurotox Res. 2020;37:406-424 pubmed 出版商
Long C, Lai Y, Li T, Nyunoya T, Zou C. Cigarette smoke extract modulates Pseudomonas aeruginosa bacterial load via USP25/HDAC11 axis in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2020;318:L252-L263 pubmed 出版商
Alsabban A, Morikawa M, Tanaka Y, Takei Y, Hirokawa N. Kinesin Kif3b mutation reduces NMDAR subunit NR2A trafficking and causes schizophrenia-like phenotypes in mice. EMBO J. 2020;39:e101090 pubmed 出版商
Gao N, Li J, Qin Y, Wang Y, Kang Q, Pei C. SNAI1 interacts with HDAC1 to control TGF‑β2‑induced epithelial‑mesenchymal transition in human lens epithelial cells. Int J Mol Med. 2020;45:265-273 pubmed 出版商
Zhang K, Lv D, Li R. Protein inhibitor of activated STAT1 (PIAS1) inhibits IRF8 activation of Epstein-Barr virus lytic gene expression. Virology. 2020;540:75-87 pubmed 出版商
He D, Lasek A. Anaplastic Lymphoma Kinase Regulates Internalization of the Dopamine D2 Receptor. Mol Pharmacol. 2020;97:123-131 pubmed 出版商
Cheng X, Huang Z, Long D, Jin W. BET inhibitor bromosporine enhances 5-FU effect in colorectal cancer cells. Biochem Biophys Res Commun. 2020;521:840-845 pubmed 出版商
Das N, Miyata H, Hara H, Chida J, Uchiyama K, Masujin K, et al. The N-Terminal Polybasic Region of Prion Protein Is Crucial in Prion Pathogenesis Independently of the Octapeptide Repeat Region. Mol Neurobiol. 2020;57:1203-1216 pubmed 出版商
Culbreth M, Rand M. Methylmercury modifies temporally expressed myogenic regulatory factors to inhibit myoblast differentiation. Toxicol In Vitro. 2020;63:104717 pubmed 出版商
Ramlan H, Damanhuri H. Effects of age on feeding response: Focus on the rostral C1 neuron and its glucoregulatory proteins. Exp Gerontol. 2020;129:110779 pubmed 出版商
Aizawa S, Yamamuro Y. Possible involvement of DNA methylation in hippocampal synaptophysin gene expression during postnatal development of mice. Neurochem Int. 2020;132:104587 pubmed 出版商
Yu Z, Wang H, Fang Y, Lu L, Li M, Yan B, et al. Molecular chaperone HspB2 inhibited pancreatic cancer cell proliferation via activating p53 downstream gene RPRM, BAI1, and TSAP6. J Cell Biochem. 2020;121:2318-2329 pubmed 出版商
Kariri Y, Joseph C, Kurozumi S, Toss M, Alsaleem M, Raafat S, et al. Prognostic significance of KN motif and ankyrin repeat domains 1 (KANK1) in invasive breast cancer. Breast Cancer Res Treat. 2020;179:349-357 pubmed 出版商
Almeida B, Barros B, Araújo A, Alcantara C, Suzuki E. Paracoccidioides species present distinct fungal adherence to epithelial lung cells and promote different IL-8 secretion levels. Med Microbiol Immunol. 2020;209:59-67 pubmed 出版商
Oksanen M, Hyötyläinen I, Trontti K, Rolova T, Wojciechowski S, Koskuvi M, et al. NF-E2-related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin-1 mutated Alzheimer's disease astrocytes. Glia. 2020;68:589-599 pubmed 出版商
Royea J, Martinot P, Hamel E. Memory and cerebrovascular deficits recovered following angiotensin IV intervention in a mouse model of Alzheimer's disease. Neurobiol Dis. 2020;134:104644 pubmed 出版商
Jang J, Kim D, Ham S, Vo M, Jeong S, Choi S, et al. Tristetraprolin posttranscriptionally downregulates PFKFB3 in cancer cells. Biochem Biophys Res Commun. 2020;521:389-394 pubmed 出版商
Bong A, Robitaille M, Milevskiy M, Roberts Thomson S, Monteith G. NCS-1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin. Mol Oncol. 2020;14:87-104 pubmed 出版商
Gao Y, Qian M, Wei Q, Duan X, Wang S, Hu H, et al. WZ66, a novel acetyl-CoA carboxylase inhibitor, alleviates nonalcoholic steatohepatitis (NASH) in mice. Acta Pharmacol Sin. 2020;41:336-347 pubmed 出版商
Nguyen D, Theodoropoulos G, Li Y, Wu C, Sha W, Feun L, et al. Targeting the Kynurenine Pathway for the Treatment of Cisplatin-Resistant Lung Cancer. Mol Cancer Res. 2020;18:105-117 pubmed 出版商
Maynard J, Ertunc O, Kulac I, Baena Del Valle J, De Marzo A, Sfanos K. IL8 Expression Is Associated with Prostate Cancer Aggressiveness and Androgen Receptor Loss in Primary and Metastatic Prostate Cancer. Mol Cancer Res. 2020;18:153-165 pubmed 出版商
Chernis N, Masschelin P, Cox A, Hartig S. Bisphenol AF promotes inflammation in human white adipocytes. Am J Physiol Cell Physiol. 2020;318:C63-C72 pubmed 出版商
Gigg J, McEwan F, Smausz R, Neill J, Harte M. Synaptic biomarker reduction and impaired cognition in the sub-chronic PCP mouse model for schizophrenia. J Psychopharmacol. 2020;34:115-124 pubmed 出版商
Tung C, Kuo L, Huang M, Wu Y, Tsai Y, Wu J, et al. MicroRNA-150-5p promotes cell motility by inhibiting c-Myb-mediated Slug suppression and is a prognostic biomarker for recurrent ovarian cancer. Oncogene. 2020;39:862-876 pubmed 出版商
Liu C, Hsu Y, Lee J, Chen M, Lin C, Huang S, et al. Targeting the pentose phosphate pathway increases reactive oxygen species and induces apoptosis in thyroid cancer cells. Mol Cell Endocrinol. 2020;499:110595 pubmed 出版商
Wardell S, Yllanes A, Chao C, Bae Y, Andreano K, Desautels T, et al. Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activity in antitumor efficacy. Breast Cancer Res Treat. 2020;179:67-77 pubmed 出版商
Li P, Shen Y, Cui P, Hu Y, Zhang Y, Miao F, et al. Neuronal NLRC5 regulates MHC class I expression in Neuro-2a cells and also during hippocampal development. J Neurochem. 2020;152:182-194 pubmed 出版商
Shin S, Jang H, Xu R, Won J, Yim H. Active PLK1-driven metastasis is amplified by TGF-β signaling that forms a positive feedback loop in non-small cell lung cancer. Oncogene. 2020;39:767-785 pubmed 出版商
Shaik F, Chelikani P. Differential effects of membrane sphingomyelin and cholesterol on agonist-induced bitter taste receptor T2R14 signaling. Mol Cell Biochem. 2020;463:57-66 pubmed 出版商
Ma J, He X, Cao Y, O Dwyer K, Szigety K, Wu Y, et al. Islet-specific Prmt5 excision leads to reduced insulin expression and glucose intolerance in mice. J Endocrinol. 2020;244:41-52 pubmed 出版商
Fraichard C, Bonnet F, Garnier A, Hebert Schuster M, Bouzerara A, Gerbaud P, et al. Placental production of progestins is fully effective in villous cytotrophoblasts and increases with the syncytiotrophoblast formation. Mol Cell Endocrinol. 2020;499:110586 pubmed 出版商
Wang S, Chen Z, Zhu S, Lu H, Peng D, Soutto M, et al. PRDX2 protects against oxidative stress induced by H. pylori and promotes resistance to cisplatin in gastric cancer. Redox Biol. 2020;28:101319 pubmed 出版商
Lin Y, Deel M, Linardic C. RASSF4 is required for skeletal muscle differentiation. Cell Biol Int. 2020;44:381-390 pubmed 出版商
Azad T, Nouri K, Janse van Rensburg H, Maritan S, Wu L, Hao Y, et al. A gain-of-functional screen identifies the Hippo pathway as a central mediator of receptor tyrosine kinases during tumorigenesis. Oncogene. 2020;39:334-355 pubmed 出版商
Liu X, Huang Q, Chen L, Zhang H, Schonbrunn E, Chen J. Tumor-derived CK1α mutations enhance MDMX inhibition of p53. Oncogene. 2020;39:176-186 pubmed 出版商
Lauterborn J, Cox C, Chan S, Vanderklish P, Lynch G, Gall C. Synaptic actin stabilization protein loss in Down syndrome and Alzheimer disease. Brain Pathol. 2020;30:319-331 pubmed 出版商
Caso J, Graell M, Navalón A, Macdowell K, Gutierrez S, Soto M, et al. Dysfunction of inflammatory pathways in adolescent female patients with anorexia nervosa. Prog Neuropsychopharmacol Biol Psychiatry. 2020;96:109727 pubmed 出版商
Ezquerro S, Becerril S, Tuero C, Méndez Giménez L, Mocha F, Moncada R, et al. Role of ghrelin isoforms in the mitigation of hepatic inflammation, mitochondrial dysfunction, and endoplasmic reticulum stress after bariatric surgery in rats. Int J Obes (Lond). 2020;44:475-487 pubmed 出版商
Wang L, Liu Y, Du T, Yang H, Lei L, Guo M, et al. ATF3 promotes erastin-induced ferroptosis by suppressing system Xc. Cell Death Differ. 2020;27:662-675 pubmed 出版商
Jiao C, Li L, Zhang P, Zhang L, Li K, Fang R, et al. REGγ ablation impedes dedifferentiation of anaplastic thyroid carcinoma and accentuates radio-therapeutic response by regulating the Smad7-TGF-β pathway. Cell Death Differ. 2020;27:497-508 pubmed 出版商
Stewart T, Azimi I, Marcial D, Peters A, Chalmers S, Yapa K, et al. Differential engagement of ORAI1 and TRPC1 in the induction of vimentin expression by different stimuli. Lab Invest. 2020;100:224-233 pubmed 出版商
Gao Y, Liu J, Mao X, He Z, Zhu T, Wang Z, et al. LncRNA FOXD1-AS1 acts as a potential oncogenic biomarker in glioma. CNS Neurosci Ther. 2020;26:66-75 pubmed 出版商
Wang Y, Zhu W, Chen L, Liang L. Early Growth Hormone Intervention Improves Glucose Metabolism in Adult Rats Born Small for Gestational Age. Exp Clin Endocrinol Diabetes. 2020;128:125-132 pubmed 出版商
Batool A, Hill T, Nguyen N, Langa E, Diviney M, Mooney C, et al. Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus. Front Neurosci. 2019;13:1404 pubmed 出版商
An H, Ma X, Liu M, Wang X, Wei X, Yuan W, et al. Stomatin plays a suppressor role in non-small cell lung cancer metastasis. Chin J Cancer Res. 2019;31:930-944 pubmed 出版商
Yu B, Yuan B, Kiyomi A, Kikuchi H, Hayashi H, Hu X, et al. Differentiation induction of human breast cancer cells by arsenite in combination with tetrandrine. Am J Transl Res. 2019;11:7310-7323 pubmed
Rodríguez Jiménez F, Clemente E, Moreno Manzano V, Erceg S. Organized Neurogenic-Niche-Like Pinwheel Structures Discovered in Spinal Cord Tissue-Derived Neurospheres. Front Cell Dev Biol. 2019;7:334 pubmed 出版商
Herrera J, Ordóñez Gutiérrez L, Fabrias G, Casas J, Morales A, Hernández G, et al. Ovarian Hormone-Dependent Effects of Dietary Lipids on APP/PS1 Mouse Brain. Front Aging Neurosci. 2019;11:346 pubmed 出版商
Jefferson M, Bone B, Buck J, Powell P. The Autophagy Protein ATG16L1 Is Required for Sindbis Virus-Induced eIF2α Phosphorylation and Stress Granule Formation. Viruses. 2019;12: pubmed 出版商
Dächert C, Gladilin E, Binder M. Gene Expression Profiling of Different Huh7 Variants Reveals Novel Hepatitis C Virus Host Factors. Viruses. 2019;12: pubmed 出版商
Wu Y, Kimura Y, Okamoto T, Matsuhisa K, Asada R, Saito A, et al. Inflammatory bowel disease-associated ubiquitin ligase RNF183 promotes lysosomal degradation of DR5 and TRAIL-induced caspase activation. Sci Rep. 2019;9:20301 pubmed 出版商
Park H, Helfman D. Up-regulated fibronectin in 3D culture facilitates spreading of triple negative breast cancer cells on 2D through integrin β-5 and Src. Sci Rep. 2019;9:19950 pubmed 出版商
Naipauer J, Rosario S, Gupta S, Premer C, Méndez Solís O, Schlesinger M, et al. PDGFRA defines the mesenchymal stem cell Kaposi's sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment. PLoS Pathog. 2019;15:e1008221 pubmed 出版商
Zhang L, Pradhan B, Guo L, Meng F, Zhong D. EGFR exon 19-deletion aberrantly regulate ERCC1 expression that may partly impaired DNA damage repair ability in non-small cell lung cancer. Thorac Cancer. 2019;: pubmed 出版商
Isfort I, Elges S, Cyra M, Berthold R, Renner M, Mechtersheimer G, et al. Prevalence of the Hippo Effectors YAP1/TAZ in Tumors of Soft Tissue and Bone. Sci Rep. 2019;9:19704 pubmed 出版商
Schiano G, Glaudemans B, Olinger E, Goelz N, Muller M, Loffing Cueni D, et al. The Urinary Excretion of Uromodulin is Regulated by the Potassium Channel ROMK. Sci Rep. 2019;9:19517 pubmed 出版商
Yau B, Blood Z, An Y, Su Z, Kebede M. Type 2 diabetes-associated single nucleotide polymorphism in Sorcs1 gene results in alternative processing of the Sorcs1 protein in INS1 β-cells. Sci Rep. 2019;9:19466 pubmed 出版商
Kim H, Lee I, Kim S, Lee J, Kim K, Park J, et al. RRAD expression in gastric and colorectal cancer with peritoneal carcinomatosis. Sci Rep. 2019;9:19439 pubmed 出版商
Bell E, Coelho P, Ratcliffe C, Rajadurai C, Peschard P, Vaillancourt R, et al. LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion. Cell Rep. 2019;29:4053-4068.e6 pubmed 出版商
Hoang H, Graber T, Jia J, Vaidya N, Gilchrist V, Xiang X, et al. Induction of an Alternative mRNA 5' Leader Enhances Translation of the Ciliopathy Gene Inpp5e and Resistance to Oncolytic Virus Infection. Cell Rep. 2019;29:4010-4023.e5 pubmed 出版商
Zhou L, Flores J, Noël A, Beauchet O, Sjöström P, LeBlanc A. Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice. Acta Neuropathol Commun. 2019;7:210 pubmed 出版商
Chumarina M, Russ K, Azevedo C, Heuer A, Pihl M, Collin A, et al. Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene. Acta Neuropathol Commun. 2019;7:208 pubmed 出版商
Noonan J, Jarzabek M, Lincoln F, Cavanagh B, Pariag A, Juric V, et al. Implementing Patient-Derived Xenografts to Assess the Effectiveness of Cyclin-Dependent Kinase Inhibitors in Glioblastoma. Cancers (Basel). 2019;11: pubmed 出版商
Fujiwara H, Tateishi K, Misumi K, Hayashi A, Igarashi K, Kato H, et al. Mutant IDH1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation. Sci Rep. 2019;9:18859 pubmed 出版商
Wambecke A, Laurent Issartel C, Leroy Dudal J, Giffard F, Cosson F, Lubin Germain N, et al. Evaluation of the potential of a new ribavirin analog impairing the dissemination of ovarian cancer cells. PLoS ONE. 2019;14:e0225860 pubmed 出版商
Tanaka Y, Konishi A, Obinata H, Tsuneoka M. Metformin activates KDM2A to reduce rRNA transcription and cell proliferation by dual regulation of AMPK activity and intracellular succinate level. Sci Rep. 2019;9:18694 pubmed 出版商
Chai Z, Yang Y, Gu Z, Cai X, Ye W, Kong L, et al. Recombinant Viral Capsid Protein L2 (rVL2) of HPV 16 Suppresses Cell Proliferation and Glucose Metabolism via ITGB7/C/EBPβ Signaling Pathway in Cervical Cancer Cell Lines. Onco Targets Ther. 2019;12:10415-10425 pubmed 出版商
Kim E, Noh H, Choi B, Park J, Kim J, Jang Y, et al. Interleukin-22 Induces the Infiltration of Visceral Fat Tissue by a Discrete Subset of Duffy Antigen Receptor for Chemokine-Positive M2-Like Macrophages in Response to a High Fat Diet. Cells. 2019;8: pubmed 出版商
Liu N, Jiang Y, Chung J, Li Y, Yu Z, Kim J, et al. Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice. Int J Mol Sci. 2019;20: pubmed 出版商
Shrum S, Rusch N, Macmillan Crow L. Specific BK Channel Activator NS11021 Protects Rat Renal Proximal Tubular Cells from Cold Storage-Induced Mitochondrial Injury In Vitro. Biomolecules. 2019;9: pubmed 出版商
Cannito S, Foglia B, Villano G, Turato C, Delgado T, Morello E, et al. SerpinB3 Differently Up-Regulates Hypoxia Inducible Factors -1α and -2α in Hepatocellular Carcinoma: Mechanisms Revealing Novel Potential Therapeutic Targets. Cancers (Basel). 2019;11: pubmed 出版商
Ibraheem K, Yhmed A, Qayyum T, Bryan N, Georgopoulos N. CD40 induces renal cell carcinoma-specific differential regulation of TRAF proteins, ASK1 activation and JNK/p38-mediated, ROS-dependent mitochondrial apoptosis. Cell Death Discov. 2019;5:148 pubmed 出版商
Volkman H, Cambier S, Gray E, Stetson D. Tight nuclear tethering of cGAS is essential for preventing autoreactivity. elife. 2019;8: pubmed 出版商
Moschinger M, Hilse K, Rupprecht A, Zeitz U, Erben R, Rülicke T, et al. Age-related sex differences in the expression of important disease-linked mitochondrial proteins in mice. Biol Sex Differ. 2019;10:56 pubmed 出版商
Satoh T, Mellett M, Meier Schiesser B, Fenini G, Otsuka A, Beer H, et al. IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes. J Clin Invest. 2019;: pubmed 出版商
Griñan Ferré C, Marsal García L, Bellver Sanchis A, Kondengaden S, Turga R, Vazquez S, et al. Pharmacological inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer's disease mouse model. Aging (Albany NY). 2019;11:11591-11608 pubmed 出版商
Kapoor I, Li Y, Sharma A, Zhu H, Bodo J, Xu W, et al. Resistance to BTK inhibition by ibrutinib can be overcome by preventing FOXO3a nuclear export and PI3K/AKT activation in B-cell lymphoid malignancies. Cell Death Dis. 2019;10:924 pubmed 出版商
Ewald L, Dittmann J, Vogler M, Fulda S. Side-by-side comparison of BH3-mimetics identifies MCL-1 as a key therapeutic target in AML. Cell Death Dis. 2019;10:917 pubmed 出版商
Schmit K, Chen J, Ayama Canden S, Fransolet M, Finet L, Demazy C, et al. Characterization of the role of TMEM45A in cancer cell sensitivity to cisplatin. Cell Death Dis. 2019;10:919 pubmed 出版商
Stein B, Calzolari D, Hellberg K, Hu Y, He L, Hung C, et al. Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks. Cell Rep. 2019;29:3331-3348.e7 pubmed 出版商
Xu Y, Liu H, Su L, Xu N, Xu D, Liu H, et al. PPARγ inhibits breast cancer progression by upregulating PTPRF expression. Eur Rev Med Pharmacol Sci. 2019;23:9965-9977 pubmed 出版商
Zhang X, Swalve H, Pijl R, Rosner F, Wensch Dorendorf M, Brenig B. Interdigital Hyperplasia in Holstein Cattle Is Associated With a Missense Mutation in the Signal Peptide Region of the Tyrosine-Protein Kinase Transmembrane Receptor Gene. Front Genet. 2019;10:1157 pubmed 出版商
Labadie T, Jegouic S, Roy P. Bluetongue Virus Nonstructural Protein 3 Orchestrates Virus Maturation and Drives Non-Lytic Egress via Two Polybasic Motifs. Viruses. 2019;11: pubmed 出版商
Ryu H, Kim H, Song J, Hwang S, Kim J, Kim J, et al. A Small Compound KJ-28d Enhances the Sensitivity of Non-Small Cell Lung Cancer to Radio- and Chemotherapy. Int J Mol Sci. 2019;20: pubmed 出版商
Skalska J, Oliveira F, Figueira T, Mello E, Gomes V, McNaughton Smith G, et al. Plant defensin PvD1 modulates the membrane composition of breast tumour-derived exosomes. Nanoscale. 2019;11:23366-23381 pubmed 出版商
Wang X, Yang L, Wang J, Zhang Y, Dong R, Wu X, et al. A mouse model of subacute liver failure with ascites induced by step-wise increased doses of (-)-epigallocatechin-3-gallate. Sci Rep. 2019;9:18102 pubmed 出版商
Chavdoula E, Habiel D, Roupakia E, Markopoulos G, Vasilaki E, Kokkalis A, et al. CHUK/IKK-α loss in lung epithelial cells enhances NSCLC growth associated with HIF up-regulation. Life Sci Alliance. 2019;2: pubmed 出版商
Barilani M, Peli V, Cherubini A, Dossena M, Dolo V, Lazzari L. NG2 as an Identity and Quality Marker of Mesenchymal Stem Cell Extracellular Vesicles. Cells. 2019;8: pubmed 出版商
Liang X, Xu C, Wang W, Li X. The DNMT1/miR-34a Axis Is Involved in the Stemness of Human Osteosarcoma Cells and Derived Stem-Like Cells. Stem Cells Int. 2019;2019:7028901 pubmed 出版商
Lajqi T, Lang G, Haas F, Williams D, Hudalla H, Bauer M, et al. Memory-Like Inflammatory Responses of Microglia to Rising Doses of LPS: Key Role of PI3Kγ. Front Immunol. 2019;10:2492 pubmed 出版商
Thomas C, Thompson A, Ahmed Z, Blanch R. Retinal Ganglion Cells Die by Necroptotic Mechanisms in a Site-Specific Manner in a Rat Blunt Ocular Injury Model. Cells. 2019;8: pubmed 出版商
Ilahibaks N, Lei Z, Mol E, Deshantri A, Jiang L, Schiffelers R, et al. Biofabrication of Cell-Derived Nanovesicles: A Potential Alternative to Extracellular Vesicles for Regenerative Medicine. Cells. 2019;8: pubmed 出版商
Kim A, Jung H, Kim Y, Kim S, Park J, Lee S, et al. The Knockdown of TREK-1 in Hippocampal Neurons Attenuate Lipopolysaccharide-Induced Depressive-Like Behavior in Mice. Int J Mol Sci. 2019;20: pubmed 出版商
Liu P, Chen H, Cheng J, Tsai W, Lee H, Wang S, et al. Association of ATG4B and Phosphorylated ATG4B Proteins with Tumorigenesis and Prognosis in Oral Squamous Cell Carcinoma. Cancers (Basel). 2019;11: pubmed 出版商
Durham B, Lopez Rodrigo E, Picarsic J, Abramson D, Rotemberg V, De Munck S, et al. Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms. Nat Med. 2019;25:1839-1842 pubmed 出版商
Şen N, Arsovic A, Meierhofer D, Brodesser S, Oberschmidt C, Canet Pons J, et al. In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism. Int J Mol Sci. 2019;20: pubmed 出版商
Wildner J, Friemel A, Jennewein L, Roth S, Ritter A, Schüttler C, et al. RITA Is Expressed in Trophoblastic Cells and Is Involved in Differentiation Processes of the Placenta. Cells. 2019;8: pubmed 出版商
Ciccone V, Zazzetta M, Morbidelli L. Comparison of the Effect of Two Hyaluronic Acid Preparations on Fibroblast and Endothelial Cell Functions Related to Angiogenesis. Cells. 2019;8: pubmed 出版商
Lin H, Lee T, Lin S, Yeh Y, Lu T, Hsu C. DDAH-2 alleviates contrast medium iopromide-induced acute kidney injury through nitric oxide synthase. Clin Sci (Lond). 2019;133:2361-2378 pubmed 出版商
Esposito E, Ahn B, Shi J, Nakamura Y, Park J, Mandeville E, et al. Brain-to-cervical lymph node signaling after stroke. Nat Commun. 2019;10:5306 pubmed 出版商
Yamaguchi H, Pantarat N, Suzuki T, Evdokiou A. Near-Infrared Photoimmunotherapy Using a Small Protein Mimetic for HER2-Overexpressing Breast Cancer. Int J Mol Sci. 2019;20: pubmed 出版商
Bracht J, Karachaliou N, Berenguer J, Pedraz Valdunciel C, Filipska M, Codony Servat C, et al. Osimertinib and pterostilbene in EGFR-mutation-positive non-small cell lung cancer (NSCLC). Int J Biol Sci. 2019;15:2607-2614 pubmed 出版商
Indramanee S, Sawanyawisuth K, Silsirivanit A, Dana P, Phoomak C, Kariya R, et al. Terminal fucose mediates progression of human cholangiocarcinoma through EGF/EGFR activation and the Akt/Erk signaling pathway. Sci Rep. 2019;9:17266 pubmed 出版商
Grebenová D, Holoubek A, Roselova P, Obr A, Brodska B, Kuzelova K. PAK1, PAK1Δ15, and PAK2: similarities, differences and mutual interactions. Sci Rep. 2019;9:17171 pubmed 出版商
Khabir M, Aliche A, Sureau C, Blanchet M, Labonte P. HDV alters the autophagy process to promote its genome replication. J Virol. 2019;: pubmed 出版商
Tong Z, Liu Y, Yu X, Martinez J, Xu J. The transcriptional co-activator NCOA6 promotes estrogen-induced GREB1 transcription by recruiting ERα and enhancing enhancer-promoter interactions. J Biol Chem. 2019;294:19667-19682 pubmed 出版商
Sakamoto S, Kagawa S, Kuwada K, Ito A, Kajioka H, Kakiuchi Y, et al. Intraperitoneal cancer-immune microenvironment promotes peritoneal dissemination of gastric cancer. Oncoimmunology. 2019;8:e1671760 pubmed 出版商
Gao P, Chai Y, Song J, Liu T, Chen P, Zhou L, et al. Reprogramming the unfolded protein response for replication by porcine reproductive and respiratory syndrome virus. PLoS Pathog. 2019;15:e1008169 pubmed 出版商
Ito M, Codony Servat C, Karachaliou N, Rosell R. Targeting PKCι-PAK1 in EGFR-mutation positive non-small cell lung cancer. Transl Lung Cancer Res. 2019;8:667-673 pubmed 出版商
Odle R, Walker S, Oxley D, Kidger A, Balmanno K, Gilley R, et al. An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis. Mol Cell. 2019;: pubmed 出版商
To T, Cuadros A, Shah H, Hung W, Li Y, Kim S, et al. A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering. Cell. 2019;179:1222-1238.e17 pubmed 出版商
Zhang S, Wang Q, Yang Q, Gu H, Yin Y, Li Y, et al. NG2 glia regulate brain innate immunity via TGF-β2/TGFBR2 axis. BMC Med. 2019;17:204 pubmed 出版商
Lo S, Byrum S, Tackett A, Parajuli N. Cold Storage Increases Albumin and Advanced Glycation-End Product-Albumin Levels in Kidney Transplants: A Possible Cause for Exacerbated Renal Damage. Transplant Direct. 2019;5:e454 pubmed 出版商
Yamaji T, Yamashita A, Wakui H, Azushima K, Uneda K, Fujikawa Y, et al. Angiotensin II type 1 receptor-associated protein deficiency attenuates sirtuin1 expression in an immortalised human renal proximal tubule cell line. Sci Rep. 2019;9:16550 pubmed 出版商
Ning J, Lin Z, Zhao X, Zhao B, Miao J. Inhibiting lysine 353 oxidation of GRP78 by a hypochlorous probe targeting endoplasmic reticulum promotes autophagy in cancer cells. Cell Death Dis. 2019;10:858 pubmed 出版商
Zhou J, Liu S, Wang Y, Dai W, Zou H, Wang S, et al. Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma. Mol Cancer. 2019;18:159 pubmed 出版商
Aivazidis S, Jain A, Rauniyar A, Anderson C, Marentette J, Orlicky D, et al. SNARE proteins rescue impaired autophagic flux in Down syndrome. PLoS ONE. 2019;14:e0223254 pubmed 出版商
Lin Y, Huang S, Wu J, Chu T, Huang S, Lee C, et al. Novel HDGF/HIF-1α/VEGF axis in oral cancer impacts disease prognosis. BMC Cancer. 2019;19:1083 pubmed 出版商
Ziegler C, Dang L, Eisenhauer P, Kelly J, King B, Klaus J, et al. NEDD4 family ubiquitin ligases associate with LCMV Z's PPXY domain and are required for virus budding, but not via direct ubiquitination of Z. PLoS Pathog. 2019;15:e1008100 pubmed 出版商
Gupta S, Ylä Anttila P, Sandalova T, Sun R, Achour A, Masucci M. 14-3-3 scaffold proteins mediate the inactivation of trim25 and inhibition of the type I interferon response by herpesvirus deconjugases. PLoS Pathog. 2019;15:e1008146 pubmed 出版商
Randzavola L, Strege K, Juzans M, Asano Y, Stinchcombe J, Gawden Bone C, et al. Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity. J Clin Invest. 2019;129:5600-5614 pubmed 出版商
Heo J, Noh B, Lee S, Lee H, Kim Y, Lim J, et al. Phosphorylation of TFCP2L1 by CDK1 is required for stem cell pluripotency and bladder carcinogenesis. EMBO Mol Med. 2019;:e10880 pubmed 出版商
Liu Y, Tang Z, Duan J, Chen L, Sun J, Zhou R, et al. ER-depletion lowering the 'hypothalamus-uterus-kidney' axis functions by perturbing the renal ERβ/Ptgds signalling pathway. Aging (Albany NY). 2019;11:9500-9529 pubmed 出版商
Kreiter J, Rupprecht A, Zimmermann L, Moschinger M, Rokitskaya T, Antonenko Y, et al. Molecular Mechanisms Responsible for Pharmacological Effects of Genipin on Mitochondrial Proteins. Biophys J. 2019;117:1845-1857 pubmed 出版商
Wen M, Xie X, Tu J, Lee D, Chen T. Generation of a genetically modified human embryonic stem cells expressing fluorescence tagged ATOX1. Stem Cell Res. 2019;41:101631 pubmed 出版商
Jiao D, Yang Z, Wang L, Hu B, Wang J, Xu A, et al. Endogenous leptin promotes autophagy in EBSS-induced PFCs. Anim Cells Syst (Seoul). 2019;23:318-325 pubmed 出版商
Young M, Bui V, Chen C, Wang H. FTY720 induces non-canonical phosphatidylserine externalization and cell death in acute myeloid leukemia. Cell Death Dis. 2019;10:847 pubmed 出版商
Abildgaard A, Stein A, Nielsen S, Schultz Knudsen K, Papaleo E, Shrikhande A, et al. Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome. elife. 2019;8: pubmed 出版商
Duman F, Akkoç Y, Demirci G, Bavili N, Kiraz A, Gozuacik D, et al. Bypassing pro-survival and resistance mechanisms of autophagy in EGFR-positive lung cancer cells by targeted delivery of 5FU using theranostic Ag2S quantum dots. J Mater Chem B. 2019;7:7363-7376 pubmed 出版商
Ayoub A, Hariss L, El Hachem N, El Achkar G, Ghayad S, Dagher O, et al. gem-Difluorobisarylic derivatives: design, synthesis and anti-inflammatory effect. BMC Chem. 2019;13:124 pubmed 出版商
Park C, Jo J, Song M, Park J, Kim Y, Youn H, et al. Secreted protein acidic and rich in cysteine mediates active targeting of human serum albumin in U87MG xenograft mouse models. Theranostics. 2019;9:7447-7457 pubmed 出版商
Santos M, Morais S, Pereira C, Sequeiros J, Alonso I. Parkin truncating variants result in a loss-of-function phenotype. Sci Rep. 2019;9:16150 pubmed 出版商
Dionísio P, Oliveira S, Gaspar M, Gama M, Castro Caldas M, Amaral J, et al. Ablation of RIP3 protects from dopaminergic neurodegeneration in experimental Parkinson's disease. Cell Death Dis. 2019;10:840 pubmed 出版商
Liu P, Tee A, Milazzo G, Hannan K, Maag J, Mondal S, et al. The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35. Nat Commun. 2019;10:5026 pubmed 出版商
Park H, Gholam Zadeh M, Suh J, Choi H. Lycorine Attenuates Autophagy in Osteoclasts via an Axis of mROS/TRPML1/TFEB to Reduce LPS-Induced Bone Loss. Oxid Med Cell Longev. 2019;2019:8982147 pubmed 出版商
Liang X, Xu C, Cao X, Wang W. Isovitexin Suppresses Cancer Stemness Property And Induces Apoptosis Of Osteosarcoma Cells By Disruption Of The DNMT1/miR-34a/Bcl-2 Axis. Cancer Manag Res. 2019;11:8923-8936 pubmed 出版商
Lombino F, Muhia M, Lopez Rojas J, Brill M, Thies E, Ruschkies L, et al. The Microtubule Severing Protein Katanin Regulates Proliferation of Neuronal Progenitors in Embryonic and Adult Neurogenesis. Sci Rep. 2019;9:15940 pubmed 出版商
Sharma P, Mahen R, Rossmann M, Stokes J, Hardwick B, Huggins D, et al. A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation. Sci Rep. 2019;9:15930 pubmed 出版商
Spiombi E, Angrisani A, Fonte S, De Feudis G, Fabretti F, Cucchi D, et al. KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2. Oncogenesis. 2019;8:64 pubmed 出版商
Roy A, Ghosh A, Kumar B, Chandran B. IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP. elife. 2019;8: pubmed 出版商
Zhou J, Chi X, Cheng M, Huang X, Liu X, Fan J, et al. Zika virus degrades the ω-3 fatty acid transporter Mfsd2a in brain microvascular endothelial cells and impairs lipid homeostasis. Sci Adv. 2019;5:eaax7142 pubmed 出版商
Lin S, Ma C, Kuo K, Su Y, Wang W, Chan T, et al. Transcription Factor Elf3 Modulates Vasopressin-Induced Aquaporin-2 Gene Expression in Kidney Collecting Duct Cells. Front Physiol. 2019;10:1308 pubmed 出版商
Cui Y, Chang R, Zhang T, Zhou X, Wang Q, Gao H, et al. Chinese Herbal Formula (CHF03) Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) Through Inhibiting Lipogenesis and Anti-Oxidation Mechanisms. Front Pharmacol. 2019;10:1190 pubmed 出版商
Katsu Jiménez Y, Gimenez Cassina A. Fibroblast growth Factor-21 promotes ketone body utilization in neurons through activation of AMP-dependent kinase. Mol Cell Neurosci. 2019;101:103415 pubmed 出版商
Song J, Kwak S, Kim H, Jun W, Lee J, Yoon H, et al. Dendropanax morbifera Branch Water Extract Increases the Immunostimulatory Activity of RAW264.7 Macrophages and Primary Mouse Splenocytes. J Med Food. 2019;22:1136-1145 pubmed 出版商
Starokadomskyy P, Wilton K, Krzewski K, Lopez A, Sifuentes Dominguez L, Overlee B, et al. NK cell defects in X-linked pigmentary reticulate disorder. JCI Insight. 2019;4: pubmed 出版商
Moore P, Qi J, Thamsen M, Ghosh R, Peng J, Gliedt M, et al. Parallel Signaling through IRE1α and PERK Regulates Pancreatic Neuroendocrine Tumor Growth and Survival. Cancer Res. 2019;79:6190-6203 pubmed 出版商
Hack C, Buck T, Bagnjuk K, Eubler K, Kunz L, Mayr D, et al. A Role for H2O2 and TRPM2 in the Induction of Cell Death: Studies in KGN Cells. Antioxidants (Basel). 2019;8: pubmed 出版商
Liu Z, Johnson S, Zhang Z, Corey D. Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes. Nucleic Acid Ther. 2019;29:323-334 pubmed 出版商
Chen J, Zhou Q, Feng J, Zheng W, Du J, Meng X, et al. Activation of AMPK promotes thyroid cancer cell migration through its interaction with PKM2 and β-catenin. Life Sci. 2019;239:116877 pubmed 出版商
Tran P, Wang T, Yin W, Tran T, Nguyen T, Lee B, et al. Aspirin-loaded nanoexosomes as cancer therapeutics. Int J Pharm. 2019;572:118786 pubmed 出版商
Kong X, Tu Y, Li B, Zhang L, Feng L, Wang L, et al. Roux-en-Y gastric bypass enhances insulin secretion in type 2 diabetes via FXR-mediated TRPA1 expression. Mol Metab. 2019;29:1-11 pubmed 出版商
Nebie O, Devos D, Vingtdeux V, Barro L, Devedjian J, Jonneaux A, et al. The neuroprotective activity of heat-treated human platelet lysate biomaterials manufactured from outdated pathogen-reduced (amotosalen/UVA) platelet concentrates. J Biomed Sci. 2019;26:89 pubmed 出版商
Sifuentes Dominguez L, Li H, Llano E, Liu Z, Singla A, Patel A, et al. SCGN deficiency results in colitis susceptibility. elife. 2019;8: pubmed 出版商
Reyes Ramos A, Ramos Cruz K, Rodríguez Merced N, Martínez Montemayor M, Franqui Ríos N, Ríos Grant J, et al. Mesenchymal Cells Support the Oncogenicity and Therapeutic Response of the Hedgehog Pathway in Triple-Negative Breast Cancer. Cancers (Basel). 2019;11: pubmed 出版商
Torregrossa F, Aguennouz M, La Torre D, Sfacteria A, Grasso G. Role of Erythropoietin in Cerebral Glioma: An Innovative Target in Neuro-Oncology. World Neurosurg. 2019;131:346-355 pubmed 出版商
Rhee M, Kim J, Lee M, Yoon K, Lee S. Preadipocyte factor 1 regulates adipose tissue browning via TNF-α-converting enzyme-mediated cleavage. Metabolism. 2019;101:153977 pubmed 出版商
Daniels E, Alders M, Lezzerini M, McDonald A, Peters M, Kuijpers T, et al. A uniparental isodisomy event introducing homozygous pathogenic variants drives a multisystem metabolic disorder. Cold Spring Harb Mol Case Stud. 2019;5: pubmed 出版商
Mirastschijski U, Lupse B, Maedler K, Sarma B, Radtke A, Belge G, et al. Matrix Metalloproteinase-3 is Key Effector of TNF-α-Induced Collagen Degradation in Skin. Int J Mol Sci. 2019;20: pubmed 出版商
Tang K, Liu X, Wang Z, Qu K, Fan R. Trehalose alleviates cadmium-induced brain damage by ameliorating oxidative stress, autophagy inhibition, and apoptosis. Metallomics. 2019;11:2043-2051 pubmed 出版商
Sinner H, Johnson J, Rychahou P, Watt D, Zaytseva Y, Liu C, et al. Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation. PLoS ONE. 2019;14:e0224253 pubmed 出版商
Glass E, Masjedi S, Dudzinski S, Wilson A, Duvall C, Yull F, et al. Optimizing Mannose "Click" Conjugation to Polymeric Nanoparticles for Targeted siRNA Delivery to Human and Murine Macrophages. ACS Omega. 2019;4:16756-16767 pubmed 出版商
Cocce K, Jasper J, Desautels T, Everett L, Wardell S, Westerling T, et al. The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer. Cell Rep. 2019;29:889-903.e10 pubmed 出版商
Yu J, Shen L, Liu Y, Ming H, Zhu X, Chu M, et al. The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling. Mol Cell Biochem. 2019;: pubmed 出版商
Di Maira G, Gentilini A, Pastore M, Caligiuri A, Piombanti B, Raggi C, et al. The protein kinase CK2 contributes to the malignant phenotype of cholangiocarcinoma cells. Oncogenesis. 2019;8:61 pubmed 出版商
Norton P, Barschke P, Scharff C, Mendoza E. Differential Song Deficits after Lentivirus-Mediated Knockdown of FoxP1, FoxP2, or FoxP4 in Area X of Juvenile Zebra Finches. J Neurosci. 2019;39:9782-9796 pubmed 出版商
Higuchi C, Yamamoto M, Shin S, Miyamoto K, Matsumoto K. Perturbation of maternal PIASy abundance disrupts zygotic genome activation and embryonic development via SUMOylation pathway. Biol Open. 2019;8: pubmed 出版商
Bera R, Chiu M, Huang Y, Lin T, Kuo M, Shih L. RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia. J Hematol Oncol. 2019;12:104 pubmed 出版商
Wang J, Xing Y, Wang Y, He Y, Wang L, Peng S, et al. A novel BMI-1 inhibitor QW24 for the treatment of stem-like colorectal cancer. J Exp Clin Cancer Res. 2019;38:422 pubmed 出版商
Lundsten S, Spiegelberg D, Stenerlow B, Nestor M. The HSP90 inhibitor onalespib potentiates 177Lu‑DOTATATE therapy in neuroendocrine tumor cells. Int J Oncol. 2019;55:1287-1295 pubmed 出版商
Chen F, Wang H, Dong Z, Wang Y, Zhang M, Li J, et al. Flaxseed oil ameliorated high-fat-diet-induced bone loss in rats by promoting osteoblastic function in rat primary osteoblasts. Nutr Metab (Lond). 2019;16:71 pubmed 出版商
Wagner M, Osborn D, Gehweiler I, Nagel M, Ulmer U, Bakhtiari S, et al. Bi-allelic variants in RNF170 are associated with hereditary spastic paraplegia. Nat Commun. 2019;10:4790 pubmed 出版商
An H, Tan J, Shelkovnikova T. Stress granules regulate stress-induced paraspeckle assembly. J Cell Biol. 2019;218:4127-4140 pubmed 出版商
Zhu K, Hu X, Chen H, Li F, Yin N, Liu A, et al. Downregulation of circRNA DMNT3B contributes to diabetic retinal vascular dysfunction through targeting miR-20b-5p and BAMBI. EBioMedicine. 2019;49:341-353 pubmed 出版商
Santos I, Ramos C, Mendès C, Sequeira C, Tomé C, Fernandes D, et al. Targeting Glutathione and Cystathionine β-Synthase in Ovarian Cancer Treatment by Selenium-Chrysin Polyurea Dendrimer Nanoformulation. Nutrients. 2019;11: pubmed 出版商
Dauber B, Saffran H, Smiley J. The herpes simplex virus host shutoff (vhs) RNase limits accumulation of double stranded RNA in infected cells: Evidence for accelerated decay of duplex RNA. PLoS Pathog. 2019;15:e1008111 pubmed 出版商
Saga K, Park J, Nimura K, Kawamura N, Ishibashi A, Nonomura N, et al. NANOG helps cancer cells escape NK cell attack by downregulating ICAM1 during tumorigenesis. J Exp Clin Cancer Res. 2019;38:416 pubmed 出版商
Mortensen A, Spiegelberg D, Brown C, Lane D, Nestor M. The Stapled Peptide PM2 Stabilizes p53 Levels and Radiosensitizes Wild-Type p53 Cancer Cells. Front Oncol. 2019;9:923 pubmed 出版商
Alijagic A, Benada O, Kofronova O, Cigna D, Pinsino A. Sea Urchin Extracellular Proteins Design a Complex Protein Corona on Titanium Dioxide Nanoparticle Surface Influencing Immune Cell Behavior. Front Immunol. 2019;10:2261 pubmed 出版商
Kim J, Kim W, Park C. Interleukin-6 mediates resistance to PI3K-pathway-targeted therapy in lymphoma. BMC Cancer. 2019;19:936 pubmed 出版商
Smith E, Somma D, Kerrigan D, McIntyre Z, Cole J, Liang K, et al. The regulation of sequence specific NF-κB DNA binding and transcription by IKKβ phosphorylation of NF-κB p50 at serine 80. Nucleic Acids Res. 2019;47:11151-11163 pubmed 出版商
Inoue D, Chew G, Liu B, Michel B, Pangallo J, D Avino A, et al. Spliceosomal disruption of the non-canonical BAF complex in cancer. Nature. 2019;574:432-436 pubmed 出版商
Chen L, Shi Y, Liu N, Wang Z, Yang R, Yan B, et al. DNA methylation modifier LSH inhibits p53 ubiquitination and transactivates p53 to promote lipid metabolism. Epigenetics Chromatin. 2019;12:59 pubmed 出版商
Sun F, Wang J, Wu X, Yang C, Zhang J. Selenium nanoparticles act as an intestinal p53 inhibitor mitigating chemotherapy-induced diarrhea in mice. Pharmacol Res. 2019;149:104475 pubmed 出版商
Santos L, Colman L, Contreras P, Chini C, Carlomagno A, Leyva A, et al. A novel form of Deleted in breast cancer 1 (DBC1) lacking the N-terminal domain does not bind SIRT1 and is dynamically regulated in vivo. Sci Rep. 2019;9:14381 pubmed 出版商
Mahamud M, Geng X, Ho Y, Cha B, Kim Y, Ma J, et al. GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126. Development. 2019;146: pubmed 出版商
Seo J, Chae Y, Kossenkov A, Lee Y, Tang H, Agarwal E, et al. MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer. Cancer Res. 2019;79:6215-6226 pubmed 出版商
Gremmels H, de Jong O, Toorop R, Michielsen L, Van Zuilen A, Vlassov A, et al. The Small RNA Repertoire of Small Extracellular Vesicles Isolated From Donor Kidney Preservation Fluid Provides a Source for Biomarker Discovery for Organ Quality and Posttransplantation Graft Function. Transplant Direct. 2019;5:e484 pubmed 出版商
Corso G, Heusermann W, Trojer D, Görgens A, Steib E, Voshol J, et al. Systematic characterization of extracellular vesicle sorting domains and quantification at the single molecule - single vesicle level by fluorescence correlation spectroscopy and single particle imaging. J Extracell Vesicles. 2019;8:1663043 pubmed 出版商
Lear T, McKelvey A, EVANKOVICH J, Rajbhandari S, Coon T, Dunn S, et al. KIAA0317 regulates pulmonary inflammation through SOCS2 degradation. JCI Insight. 2019;4: pubmed 出版商
Wojnarowicz P, Lima e Silva R, Ohnaka M, Lee S, Chin Y, Kulukian A, et al. A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization. Cell Rep. 2019;29:62-75.e7 pubmed 出版商
Rue L, Timmers M, Lenaerts A, Smolders S, Poppe L, de Boer A, et al. Reducing EphA4 before disease onset does not affect survival in a mouse model of Amyotrophic Lateral Sclerosis. Sci Rep. 2019;9:14112 pubmed 出版商
Mendès C, Lopes Coelho F, Ramos C, Martins F, Santos I, Rodrigues A, et al. Unraveling FATP1, regulated by ER-β, as a targeted breast cancer innovative therapy. Sci Rep. 2019;9:14107 pubmed 出版商
Sanchez David R, Combredet C, Najburg V, Millot G, Beauclair G, Schwikowski B, et al. LGP2 binds to PACT to regulate RIG-I- and MDA5-mediated antiviral responses. Sci Signal. 2019;12: pubmed 出版商
Zaimoku R, Miyashita T, Tajima H, Takamura H, Harashima A, Munesue S, et al. Monitoring of Heat Shock Response and Phenotypic Changes in Hepatocellular Carcinoma After Heat Treatment. Anticancer Res. 2019;39:5393-5401 pubmed 出版商
Fasolo F, Patrucco L, Volpe M, Bon C, Peano C, Mignone F, et al. The RNA-binding protein ILF3 binds to transposable element sequences in SINEUP lncRNAs. FASEB J. 2019;33:13572-13589 pubmed 出版商
Tripathi A, Thangaraj A, Chivero E, Periyasamy P, Callen S, Burkovetskaya M, et al. Antiretroviral-Mediated Microglial Activation Involves Dysregulated Autophagy and Lysosomal Dysfunction. Cells. 2019;8: pubmed 出版商
Kenéz A, Ruda L, Danicke S, Huber K. Insulin signaling and insulin response in subcutaneous and retroperitoneal adipose tissue in Holstein cows during the periparturient period. J Dairy Sci. 2019;102:11718-11729 pubmed 出版商
Zhou S, Ge X, Kong C, Liu T, Liu A, Gao P, et al. Characterizing the PRRSV nsp2 Deubiquitinase Reveals Dispensability of Cis-Activity for Replication and a Link of nsp2 to Inflammation Induction. Viruses. 2019;11: pubmed 出版商
Pesini A, Iglesias E, Bayona Bafaluy M, Garrido Pérez N, Meade P, Gaudó P, et al. Brain pyrimidine nucleotide synthesis and Alzheimer disease. Aging (Albany NY). 2019;11:8433-8462 pubmed 出版商
Rassu M, Biosa A, Galioto M, Fais M, Sini P, Greggio E, et al. Levetiracetam treatment ameliorates LRRK2 pathological mutant phenotype. J Cell Mol Med. 2019;23:8505-8510 pubmed 出版商
Mol E, Lei Z, Roefs M, Bakker M, Goumans M, Doevendans P, et al. Injectable Supramolecular Ureidopyrimidinone Hydrogels Provide Sustained Release of Extracellular Vesicle Therapeutics. Adv Healthc Mater. 2019;8:e1900847 pubmed 出版商
Credendino S, Bellone M, Lewin N, Amendola E, Sanges R, Basu S, et al. A ceRNA Circuitry Involving the Long Noncoding RNA Klhl14-AS, Pax8, and Bcl2 Drives Thyroid Carcinogenesis. Cancer Res. 2019;79:5746-5757 pubmed 出版商
Brown C, Del Corsso C, Zoidl C, Donaldson L, Spray D, Zoidl G. Tubulin-Dependent Transport of Connexin-36 Potentiates the Size and Strength of Electrical Synapses. Cells. 2019;8: pubmed 出版商
Jang J, Han D, Golkaram M, Audouard M, Liu G, Bridges D, et al. Control over single-cell distribution of G1 lengths by WNT governs pluripotency. PLoS Biol. 2019;17:e3000453 pubmed 出版商
Tawfik D, Groth C, Gundlach J, Peipp M, Kabelitz D, Becker T, et al. TRAIL-Receptor 4 Modulates γδ T Cell-Cytotoxicity Toward Cancer Cells. Front Immunol. 2019;10:2044 pubmed 出版商
Sackmann V, Sinha M, Sackmann C, Civitelli L, Bergström J, Ansell Schultz A, et al. Inhibition of nSMase2 Reduces the Transfer of Oligomeric α-Synuclein Irrespective of Hypoxia. Front Mol Neurosci. 2019;12:200 pubmed 出版商
Li Q, Zhao Q, Zhang J, Zhou L, Zhang W, Chua B, et al. The Protein Phosphatase 1 Complex Is a Direct Target of AKT that Links Insulin Signaling to Hepatic Glycogen Deposition. Cell Rep. 2019;28:3406-3422.e7 pubmed 出版商
Sánchez Martín V, Jiménez García L, Herranz S, Luque A, Acebo P, Amesty A, et al. α-Hispanolol Induces Apoptosis and Suppresses Migration and Invasion of Glioblastoma Cells Likely via Downregulation of MMP-2/9 Expression and p38MAPK Attenuation. Front Pharmacol. 2019;10:935 pubmed 出版商
Huang K, O Neill K, Li J, Zhou W, Han N, Pang X, et al. BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis. Cell Res. 2019;29:942-952 pubmed 出版商
Sakai K, Ito C, Wakabayashi M, Kanzaki S, Ito T, Takada S, et al. Usp26 mutation in mice leads to defective spermatogenesis depending on genetic background. Sci Rep. 2019;9:13757 pubmed 出版商
Li Y, Li R, Ouyang N, Dai K, Yuan P, Zheng L, et al. Investigating the impact of local inflammation on granulosa cells and follicular development in women with ovarian endometriosis. Fertil Steril. 2019;112:882-891.e1 pubmed 出版商
Armstrong C, Cassimeris L, da Silva Santos C, Micoogullari Y, Wagner B, Babasyan S, et al. The expression of equine keratins K42 and K124 is restricted to the hoof epidermal lamellae of Equus caballus. PLoS ONE. 2019;14:e0219234 pubmed 出版商
Su C, Yan R, Hsu W, Chu C, Chang H, Lai C, et al. Phosphorylation of adducin-1 by cyclin-dependent kinase 5 is important for epidermal growth factor-induced cell migration. Sci Rep. 2019;9:13703 pubmed 出版商
Granato M, Gilardini Montani M, Zompetta C, Santarelli R, Gonnella R, Romeo M, et al. Quercetin Interrupts the Positive Feedback Loop Between STAT3 and IL-6, Promotes Autophagy, and Reduces ROS, Preventing EBV-Driven B Cell Immortalization. Biomolecules. 2019;9: pubmed 出版商
Hwang S, Shin D, Hong J. Drug Repurposing as an Antitumor Agent: Disulfiram-Mediated Carbonic Anhydrase 12 and Anion Exchanger 2 Modulation to Inhibit Cancer Cell Migration. Molecules. 2019;24: pubmed 出版商
Su C, Zhao J, Hong X, Yang S, Jiang Y, Hou J. Microarray‑based analysis of COL11A1 and TWIST1 as important differentially‑expressed pathogenic genes between left and right‑sided colon cancer. Mol Med Rep. 2019;20:4202-4214 pubmed 出版商
Hah Y, Cho H, Jo S, Park Y, Heo E, Yoon T. Nicotinamide N‑methyltransferase induces the proliferation and invasion of squamous cell carcinoma cells. Oncol Rep. 2019;42:1805-1814 pubmed 出版商
Ishihara S, Onoda N, Noda S, Asano Y, Tauchi Y, Morisaki T, et al. Sorafenib inhibits vascular endothelial cell proliferation stimulated by anaplastic thyroid cancer cells regardless of BRAF mutation status. Int J Oncol. 2019;55:1069-1076 pubmed 出版商
Lipinski S, Pfeuffer S, Arnold P, Treitz C, Aden K, Ebsen H, et al. Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles. EMBO J. 2019;38:e101266 pubmed 出版商
Clough B, Finethy R, Khan R, Fisch D, Jordan S, Patel H, et al. C57BL/6 and 129 inbred mouse strains differ in Gbp2 and Gbp2b expression in response to inflammatory stimuli in vivo. Wellcome Open Res. 2019;4:124 pubmed 出版商
Sciacca M, Belgorosky D, Zambrano M, Gómez Escalante J, Roca F, Langle Y, et al. Inhibition of breast tumor growth by N(G)-nitro-l-arginine methyl ester (l-NAME) is accompanied by activation of fibroblasts. Nitric Oxide. 2019;93:34-43 pubmed 出版商
Furlong R, Lindsay A, Anderson K, Hawkins P, Sullivan A, O Neill C. The Parkinson's disease gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P3. J Cell Sci. 2019;132: pubmed 出版商
Vo D, Hartig R, Weinert S, Haybaeck J, Nass N. G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells. Biomolecules. 2019;9: pubmed 出版商
Cho E, Chen Z, Lee J, Lee S, Lee T. PSTP-3,5-Me Inhibits Osteoclast Differentiation and Bone Resorption. Molecules. 2019;24: pubmed 出版商
Kim S, Jo C, Kim G. Effects of empagliflozin on nondiabetic salt-sensitive hypertension in uninephrectomized rats. Hypertens Res. 2019;42:1905-1915 pubmed 出版商
Hester A, Salzmann B, Rahmeh M, Kolben T, Czogalla B, Ditsch N, et al. EP3 receptor antagonist L798,106 reduces proliferation and migration of SK-BR-3 breast cancer cells. Onco Targets Ther. 2019;12:6053-6068 pubmed 出版商
Bernkopf D, Brückner M, Hadjihannas M, Behrens J. An aggregon in conductin/axin2 regulates Wnt/β-catenin signaling and holds potential for cancer therapy. Nat Commun. 2019;10:4251 pubmed 出版商
Bracht J, Karachaliou N, Bivona T, Lanman R, Faull I, Nagy R, et al. BRAF Mutations Classes I, II, and III in NSCLC Patients Included in the SLLIP Trial: The Need for a New Pre-Clinical Treatment Rationale. Cancers (Basel). 2019;11: pubmed 出版商
Masamsetti V, Low R, Mak K, O Connor A, Riffkin C, Lamm N, et al. Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection. Nat Commun. 2019;10:4224 pubmed 出版商
Amer S, Alsayegh F, Mashaal Z, Mohamed S, Shawa N, Rajan K, et al. Role of TGF‑β in the motility of ShcD‑overexpressing 293 cells. Mol Med Rep. 2019;20:2667-2674 pubmed 出版商
Li J, He J, Wang Y, Shu Y, Zhou J. SMC1 promotes proliferation and inhibits apoptosis through the NF‑κB signaling pathway in colorectal cancer. Oncol Rep. 2019;: pubmed 出版商
Khazaei G, Shamsabadi F, Yamchi A, Golalipour M, Jhingan G, Shahbazi M. Proteomics evaluation of MDA-MB-231 breast cancer cells in response to RNAi-induced silencing of hPTTG. Life Sci. 2019;239:116873 pubmed 出版商
Hadadi Bechor S, Haim Y, Pecht T, Gat R, Tarnovscki T, Gericke M, et al. Autophagy differentially regulates macrophage lipid handling depending on the lipid substrate (oleic acid vs. acetylated-LDL) and inflammatory activation state. Biochim Biophys Acta Mol Cell Biol Lipids. 2019;1864:158527 pubmed 出版商
Tendilla Beltran H, Meneses Prado S, Vazquez Roque R, Tapia Rodríguez M, Vázquez Hernández A, Coatl Cuaya H, et al. Risperidone Ameliorates Prefrontal Cortex Neural Atrophy and Oxidative/Nitrosative Stress in Brain and Peripheral Blood of Rats with Neonatal Ventral Hippocampus Lesion. J Neurosci. 2019;39:8584-8599 pubmed 出版商
Takahashi Y, Liang X, Hattori T, Tang Z, He H, Chen H, et al. VPS37A directs ESCRT recruitment for phagophore closure. J Cell Biol. 2019;218:3336-3354 pubmed 出版商
Hata T, Rajabi H, Takahashi H, Yasumizu Y, Li W, Jin C, et al. MUC1-C Activates the NuRD Complex to Drive Dedifferentiation of Triple-Negative Breast Cancer Cells. Cancer Res. 2019;79:5711-5722 pubmed 出版商
Meyer S, Scuoppo C, Vlasevska S, Bal E, Holmes A, Holloman M, et al. Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma. Immunity. 2019;51:535-547.e9 pubmed 出版商
Huynh T, Chen P, Yang S, Lin F, Su T, Chen L, et al. New 1,4-Dienonesteroids from the Octocoral Dendronephthya sp. Mar Drugs. 2019;17: pubmed 出版商
Forouzanfar F, Ali S, Wallet C, De Rovere M, Ducloy C, El Mekdad H, et al. HIV-1 Vpr mediates the depletion of the cellular repressor CTIP2 to counteract viral gene silencing. Sci Rep. 2019;9:13154 pubmed 出版商
Jiang P, Huang M, Qi W, Wang F, Yang T, Gao T, et al. FUBP1 promotes neuroblastoma proliferation via enhancing glycolysis-a new possible marker of malignancy for neuroblastoma. J Exp Clin Cancer Res. 2019;38:400 pubmed 出版商
Barbero G, Castro M, Villanueva M, Quezada M, Fernández N, Demorrow S, et al. An Autocrine Wnt5a Loop Promotes NF-κB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma. Cells. 2019;8: pubmed 出版商
Mitani A, Kobayashi T, Hayashi Y, Matsushita N, Matsushita S, Nakao S, et al. Characterization of doxycycline-dependent inducible Simian Virus 40 large T antigen immortalized human conjunctival epithelial cell line. PLoS ONE. 2019;14:e0222454 pubmed 出版商
Doix B, Trempolec N, Riant O, Feron O. Low Photosensitizer Dose and Early Radiotherapy Enhance Antitumor Immune Response of Photodynamic Therapy-Based Dendritic Cell Vaccination. Front Oncol. 2019;9:811 pubmed 出版商
Jodoin R, Carrier J, Rivard N, Bisaillon M, Perreault J. G-quadruplex located in the 5'UTR of the BAG-1 mRNA affects both its cap-dependent and cap-independent translation through global secondary structure maintenance. Nucleic Acids Res. 2019;47:10247-10266 pubmed 出版商
Wu Y, Doepner M, Hojnacki T, Feng Z, Katona B, He X, et al. Disruption of the menin-MLL interaction triggers menin protein degradation via ubiquitin-proteasome pathway. Am J Cancer Res. 2019;9:1682-1694 pubmed
Wang Q, He Y, Kan W, Li F, Ji X, Wu X, et al. microRNA-32-5p targets KLF2 to promote gastric cancer by activating PI3K/AKT signaling pathway. Am J Transl Res. 2019;11:4895-4908 pubmed
Cai Y, Jia R, Xiong H, Ren Q, Zuo W, Lin T, et al. Integrative gene expression profiling reveals that dysregulated triple microRNAs confer paclitaxel resistance in non-small cell lung cancer via co-targeting MAPT. Cancer Manag Res. 2019;11:7391-7404 pubmed 出版商
Riehle K, Kenerson H, Riggle K, Turnham R, Sullivan K, Bauer R, et al. Neurotensin as a source of cyclic AMP and co-mitogen in fibrolamellar hepatocellular carcinoma. Oncotarget. 2019;10:5092-5102 pubmed 出版商
Hernández Bule M, Medel E, Colastra C, Roldan R, Ubeda A. Response of neuroblastoma cells to RF currents as a function of the signal frequency. BMC Cancer. 2019;19:889 pubmed 出版商
Kong X, Li B, Deng Y, Ma X. FXR Mediates Adenylyl Cyclase 8 Expression in Pancreatic β-Cells. J Diabetes Res. 2019;2019:8915818 pubmed 出版商
Liang X, Arullampalam P, Yang Z, Ming X. Hypoxia Enhances Endothelial Intercellular Adhesion Molecule 1 Protein Level Through Upregulation of Arginase Type II and Mitochondrial Oxidative Stress. Front Physiol. 2019;10:1003 pubmed 出版商
Meurer S, Wimmer A, Leur E, Weiskirchen R. Endoglin Trafficking/Exosomal Targeting in Liver Cells Depends on N-Glycosylation. Cells. 2019;8: pubmed 出版商
Meister M, Boedicker C, Linder B, Kogel D, Klingebiel T, Fulda S. Concomitant targeting of Hedgehog signaling and MCL-1 synergistically induces cell death in Hedgehog-driven cancer cells. Cancer Lett. 2019;465:1-11 pubmed 出版商
Nishikawa S, Itoh Y, Tokugawa M, Inoue Y, Nakashima K, Hori Y, et al. Kurarinone from Sophora Flavescens Roots Triggers ATF4 Activation and Cytostatic Effects Through PERK Phosphorylation. Molecules. 2019;24: pubmed 出版商
Beuzelin D, Pitard B, Kaeffer B. Oral Delivery of miRNA With Lipidic Aminoglycoside Derivatives in the Breastfed Rat. Front Physiol. 2019;10:1037 pubmed 出版商
Hixson K, Cogswell M, Brooks Kayal A, Russek S. Evidence for a non-canonical JAK/STAT signaling pathway in the synthesis of the brain's major ion channels and neurotransmitter receptors. BMC Genomics. 2019;20:677 pubmed 出版商
Wallroth A, Koch P, Marat A, Krause E, Haucke V. Protein kinase N controls a lysosomal lipid switch to facilitate nutrient signalling via mTORC1. Nat Cell Biol. 2019;21:1093-1101 pubmed 出版商
Dodson L, Baldan A, Nissbeck M, Gunja S, Bonnen P, Aubert G, et al. From incomplete penetrance with normal telomere length to severe disease and telomere shortening in a family with monoallelic and biallelic PARN pathogenic variants. Hum Mutat. 2019;40:2414-2429 pubmed 出版商
Hsiao C, Ji A, Chang C, Chien M, Lee L, Ho J. Mesenchymal stem cells restore the sperm motility from testicular torsion-detorsion injury by regulation of glucose metabolism in sperm. Stem Cell Res Ther. 2019;10:270 pubmed 出版商
Olinger E, Lake J, Sheehan S, Schiano G, Takata T, Tokonami N, et al. Hepsin-mediated Processing of Uromodulin is Crucial for Salt-sensitivity and Thick Ascending Limb Homeostasis. Sci Rep. 2019;9:12287 pubmed 出版商
Schipper K, Seinstra D, Paulien Drenth A, van der Burg E, Ramovs V, Sonnenberg A, et al. Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin. Nat Commun. 2019;10:3800 pubmed 出版商
Wang J, Wang X, He Y, Jia L, Yang C, Reiter R, et al. Antioxidant and Pro-Oxidant Activities of Melatonin in the Presence of Copper and Polyphenols In Vitro and In Vivo. Cells. 2019;8: pubmed 出版商
Mayor Ruiz C, Jaeger M, Bauer S, Brand M, Sin C, Hanzl A, et al. Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation. Mol Cell. 2019;75:849-858.e8 pubmed 出版商
Jahng J, Alsaadi R, Palanivel R, Song E, Hipolito V, Sung H, et al. Iron overload inhibits late stage autophagic flux leading to insulin resistance. EMBO Rep. 2019;20:e47911 pubmed 出版商
Deng X, Li S, Sun F. Necrostatin-1 Prevents Necroptosis in Brains after Ischemic Stroke via Inhibition of RIPK1-Mediated RIPK3/MLKL Signaling. Aging Dis. 2019;10:807-817 pubmed 出版商
Feng C, Chen N, Sung C, Kuo H, Yang S, Chen C, et al. Therapeutic Effect of Modulating TREM-1 via Anti-inflammation and Autophagy in Parkinson's Disease. Front Neurosci. 2019;13:769 pubmed 出版商
Zhang Z, Yu X, Zhou Z, Li B, Peng J, Wu X, et al. LMP1-positive extracellular vesicles promote radioresistance in nasopharyngeal carcinoma cells through P38 MAPK signaling. Cancer Med. 2019;8:6082-6094 pubmed 出版商
He C, Larson Casey J, Davis D, Hanumanthu V, Longhini A, Thannickal V, et al. NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosis. JCI Insight. 2019;4: pubmed 出版商
Shiozaki A, Yamazato Y, Kosuga T, Kudou M, Shoda K, Arita T, et al. Effect of low temperature on the regulation of cell volume after hypotonic shock in gastric cancer cells. Int J Oncol. 2019;55:905-914 pubmed 出版商
Hamada H, Yamamura M, Ohi H, Kobayashi Y, Niwa K, Oyama T, et al. Characterization of the human zinc finger nfx‑1‑type containing 1 encoding ZNFX1 gene and its response to 12‑O‑tetradecanoyl‑13‑acetate in HL‑60 cells. Int J Oncol. 2019;55:896-904 pubmed 出版商
O Neill L, McCormick J, Gao W, Veale D, McCarthy G, Murphy C, et al. Interleukin-6 does not upregulate pro-inflammatory cytokine expression in an ex vivo model of giant cell arteritis. Rheumatol Adv Pract. 2019;3:rkz011 pubmed 出版商
Dembitz V, Tomic B, Kodvanj I, Simon J, Bedalov A, Visnjic D. The ribonucleoside AICAr induces differentiation of myeloid leukemia by activating the ATR/Chk1 via pyrimidine depletion. J Biol Chem. 2019;294:15257-15270 pubmed 出版商
Schuhmann M, Stoll G, Papp L, Bohr A, Volkmann J, Fluri F. Electrical Stimulation of the Mesencephalic Locomotor Region Has No Impact on Blood-Brain Barrier Alterations after Cerebral Photothrombosis in Rats. Int J Mol Sci. 2019;20: pubmed 出版商
Shiau M, Chuang P, Yang C, Hsiao C, Chang S, Chang K, et al. Mechanism of Interleukin-4 Reducing Lipid Deposit by Regulating Hormone-Sensitive Lipase. Sci Rep. 2019;9:11974 pubmed 出版商
Vidoni C, Ferraresi A, Secomandi E, Vallino L, Gardin C, Zavan B, et al. Autophagy drives osteogenic differentiation of human gingival mesenchymal stem cells. Cell Commun Signal. 2019;17:98 pubmed 出版商
Salama M, Liu M, Clarke C, Espaillat M, Haley J, Jin T, et al. PKCα is required for Akt-mTORC1 activation in non-small cell lung carcinoma (NSCLC) with EGFR mutation. Oncogene. 2019;38:7311-7328 pubmed 出版商
Li M, Wang Y, Xia X, Mo P, Xu J, Yu C, et al. Steroid receptor coactivator 3 inhibits hepatitis B virus gene expression through activating Akt signaling to prevent HNF4α nuclear translocation. Cell Biosci. 2019;9:64 pubmed 出版商
Ma Q, Lu Y, Lin J, Gu Y. ENKUR acts as a tumor suppressor in lung adenocarcinoma cells through PI3K/Akt and MAPK/ERK signaling pathways. J Cancer. 2019;10:3975-3984 pubmed 出版商
Mert U, Adawy A, Scharff E, Teichmann P, Willms A, Haselmann V, et al. TRAIL Induces Nuclear Translocation and Chromatin Localization of TRAIL Death Receptors. Cancers (Basel). 2019;11: pubmed 出版商
Zhao L, Liu Z, Yang F, Zhang Y, Xue Y, Miao H, et al. Intrabody against prolyl hydroxylase 2 promotes angiogenesis by stabilizing hypoxia-inducible factor-1α. Sci Rep. 2019;9:11861 pubmed 出版商
Bagnjuk K, Kast V, Tiefenbacher A, Kaseder M, Yanase T, Burges A, et al. Inhibitor of apoptosis proteins are potential targets for treatment of granulosa cell tumors - implications from studies in KGN. J Ovarian Res. 2019;12:76 pubmed 出版商
Hsieh M, Choe J, Gadhvi J, Kim Y, Arguez M, Palmer M, et al. p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas. Cell Rep. 2019;28:1860-1878.e9 pubmed 出版商
Tang Z, Takahashi Y, He H, Hattori T, Chen C, Liang X, et al. TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion. Cell Rep. 2019;28:1744-1757.e5 pubmed 出版商
Elhassan Y, Kluckova K, Fletcher R, Schmidt M, Garten A, Doig C, et al. Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures. Cell Rep. 2019;28:1717-1728.e6 pubmed 出版商
Calsina B, Castro Vega L, Torres Pérez R, Inglada Pérez L, Currás Freixes M, Roldan Romero J, et al. Integrative multi-omics analysis identifies a prognostic miRNA signature and a targetable miR-21-3p/TSC2/mTOR axis in metastatic pheochromocytoma/paraganglioma. Theranostics. 2019;9:4946-4958 pubmed 出版商
Yamada M, Hayashi H, Suzuki K, Sato S, Inoue D, Iwatani Y, et al. Furin-mediated cleavage of LRP1 and increase in ICD of LRP1 after cerebral ischemia and after exposure of cultured neurons to NMDA. Sci Rep. 2019;9:11782 pubmed 出版商
Spatola B, Lo J, Wang B, Curran S. Nuclear and cytoplasmic WDR-23 isoforms mediate differential effects on GEN-1 and SKN-1 substrates. Sci Rep. 2019;9:11783 pubmed 出版商
Schroer A, Mohamed J, Willard M, Setola V, OESTREICH E, Siderovski D. A role for Regulator of G protein Signaling-12 (RGS12) in the balance between myoblast proliferation and differentiation. PLoS ONE. 2019;14:e0216167 pubmed 出版商
Cui D, Dai X, Shu J, Ma Y, Wei D, Xiong X, et al. The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth. Cell Death Differ. 2019;: pubmed 出版商
Mo D, Li X, Raabe C, Cui D, Vollmar J, Rozhdestvensky T, et al. A universal approach to investigate circRNA protein coding function. Sci Rep. 2019;9:11684 pubmed 出版商
Lietzén N, Hirvonen K, Honkimaa A, Buchacher T, Laiho J, Oikarinen S, et al. Coxsackievirus B Persistence Modifies the Proteome and the Secretome of Pancreatic Ductal Cells. iScience. 2019;19:340-357 pubmed 出版商
Lim S, Shin Y, Luo K, Quan Y, Cui S, Ko E, et al. Ginseng increases Klotho expression by FoxO3-mediated manganese superoxide dismutase in a mouse model of tacrolimus-induced renal injury. Aging (Albany NY). 2019;11:5548-5569 pubmed 出版商
Uxa S, Bernhart S, Mages C, Fischer M, Kohler R, Hoffmann S, et al. DREAM and RB cooperate to induce gene repression and cell-cycle arrest in response to p53 activation. Nucleic Acids Res. 2019;47:9087-9103 pubmed 出版商
Zhang H, Gao Q, Tan S, You J, Lyu C, Zhang Y, et al. SET8 prevents excessive DNA methylation by methylation-mediated degradation of UHRF1 and DNMT1. Nucleic Acids Res. 2019;: pubmed 出版商
Tan M, Sandanaraj E, Chong Y, Lim S, Koh L, Ng W, et al. A STAT3-based gene signature stratifies glioma patients for targeted therapy. Nat Commun. 2019;10:3601 pubmed 出版商
Xu Z, Tan J, Xu H, Hill C, Ostrovskaya O, Martemyanov K, et al. Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling. Nat Commun. 2019;10:3622 pubmed 出版商
Marques C, Gonçalves A, Pereira P, Almeida D, Martins B, Fontes Ribeiro C, et al. The dipeptidyl peptidase 4 inhibitor sitagliptin improves oxidative stress and ameliorates glomerular lesions in a rat model of type 1 diabetes. Life Sci. 2019;234:116738 pubmed 出版商
Li W, Guo F, Jiang X, Li Y, Li X, Yu Z. Compound ammonium glycyrrhizin protects hepatocytes from injury induced by lipopolysaccharide/florfenicol through oxidative stress and a MAPK pathway. Comp Biochem Physiol C Toxicol Pharmacol. 2019;225:108585 pubmed 出版商
Li J, Zhu X, Wang H, Lee C, Chen S, Qian Y, et al. Akt1-mediated CPR cooling protection targets regulators of metabolism, inflammation and contractile function in mouse cardiac arrest. PLoS ONE. 2019;14:e0220604 pubmed 出版商
Stein B, Herzig S, Martinez Bartolome S, Lavallée Adam M, Shaw R, Yates J. Comparison of CRISPR Genomic Tagging for Affinity Purification and Endogenous Immunoprecipitation Coupled with Quantitative Mass Spectrometry To Identify the Dynamic AMPKα2 Interactome. J Proteome Res. 2019;18:3703-3714 pubmed 出版商
Kinoshita H, Maki T, Yasuda K, Kishida N, Sasaoka N, Takagi Y, et al. KUS121, a valosin-containing protein modulator, attenuates ischemic stroke via preventing ATP depletion. Sci Rep. 2019;9:11519 pubmed 出版商
Rasheduzzaman M, Yin H, Park S. Cardiac glycoside sensitized hepatocellular carcinoma cells to TRAIL via ROS generation, p38MAPK, mitochondrial transition, and autophagy mediation. Mol Carcinog. 2019;58:2040-2051 pubmed 出版商
Tan H, Liang Z, Yao Y, Wu D, Mo H, Gu J, et al. Lasting DNA Damage and Aberrant DNA Repair Gene Expression Profile Are Associated with Post-Chronic Cadmium Exposure in Human Bronchial Epithelial Cells. Cells. 2019;8: pubmed 出版商
Yu H, Alruwaili N, Hu B, Kelly M, Zhang B, Sun D, et al. Potential role of cartilage oligomeric matrix protein in the modulation of pulmonary arterial smooth muscle superoxide by hypoxia. Am J Physiol Lung Cell Mol Physiol. 2019;317:L569-L577 pubmed 出版商
Chen L, Yang Z, Wang Y, Du L, Li Y, Zhang N, et al. Single xenotransplant of rat brown adipose tissue prolonged the ovarian lifespan of aging mice by improving follicle survival. Aging Cell. 2019;18:e13024 pubmed 出版商
Goan Y, Liu P, Chang H, Chen H, Chen W, Kuo S, et al. Kinome-Wide Screening with Small Interfering RNA Identified Polo-like Kinase 1 as a Key Regulator of Proliferation in Oral Cancer Cells. Cancers (Basel). 2019;11: pubmed 出版商
Ha Thi H, Kim H, Kim Y, Hong S. MicroRNA-130a modulates a radiosensitivity of rectal cancer by targeting SOX4. Neoplasia. 2019;21:882-892 pubmed 出版商
Lin X, Yang Y, Guo Y, Liu H, Jiang J, Zheng F, et al. PTTG1 is involved in TNF-α-related hepatocellular carcinoma via the induction of c-myc. Cancer Med. 2019;8:5702-5715 pubmed 出版商
Liu X, Zhou J, Mao Y, Ji Q, Qian S. Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates. Nat Chem Biol. 2019;15:865-871 pubmed 出版商
Tews D, Pula T, Funcke J, Jastroch M, Keuper M, Debatin K, et al. Elevated UCP1 levels are sufficient to improve glucose uptake in human white adipocytes. Redox Biol. 2019;26:101286 pubmed 出版商
Lee S, Chang H, Kim H, Choi J, Kim J, Kim J, et al. Effects of Stuffer DNA on the Suppression of Choroidal Neovascularization by a rAAV Expressing a mTOR-Inhibiting shRNA. Mol Ther Methods Clin Dev. 2019;14:171-179 pubmed 出版商
Rossetti A, Paladini M, Trepci A, Mallien A, Riva M, Gass P, et al. Differential Neuroinflammatory Response in Male and Female Mice: A Role for BDNF. Front Mol Neurosci. 2019;12:166 pubmed 出版商
Mao X, Zhou H, Jin W. Ferroptosis Induction in Pentylenetetrazole Kindling and Pilocarpine-Induced Epileptic Seizures in Mice. Front Neurosci. 2019;13:721 pubmed 出版商
Towers C, Fitzwalter B, Regan D, Goodspeed A, Morgan M, Liu C, et al. Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition. Dev Cell. 2019;50:690-703.e6 pubmed 出版商
Şen N, Canet Pons J, Halbach M, Arsovic A, Pilatus U, Chae W, et al. Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation. Neurobiol Dis. 2019;132:104559 pubmed 出版商
Zhang S, Hao S, Qiu Z, Wang Y, Zhao Y, Li Y, et al. Cadmium disrupts the DNA damage response by destabilizing RNF168. Food Chem Toxicol. 2019;133:110745 pubmed 出版商
Bae J, Choi S, Isono K, Lee J, Park S, Choi C, et al. Phc2 controls hematopoietic stem and progenitor cell mobilization from bone marrow by repressing Vcam1 expression. Nat Commun. 2019;10:3496 pubmed 出版商
Arias C, Saavedra N, Saavedra K, Alvear M, Cuevas A, Stuchi Maria Engler S, et al. Propolis Reduces the Expression of Autophagy-Related Proteins in Chondrocytes under Interleukin-1β Stimulus. Int J Mol Sci. 2019;20: pubmed 出版商
Taneera J, Dhaiban S, Mohammed A, Mukhopadhyay D, Aljaibeji H, Sulaiman N, et al. GNAS gene is an important regulator of insulin secretory capacity in pancreatic β-cells. Gene. 2019;715:144028 pubmed 出版商
Chen S, Hu X, Cui I, Wu S, Dou C, Liu Y, et al. An endogenous retroviral element exerts an antiviral innate immune function via the derived lncRNA lnc-ALVE1-AS1. Antiviral Res. 2019;170:104571 pubmed 出版商
Ishii J, Suzuki A, Kimura T, Tateyama M, Tanaka T, Yazawa T, et al. Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7. Commun Biol. 2019;2:270 pubmed 出版商
Zhou S, Ma X, Wang Z, Zhang W, Jiang H, Li S, et al. Research on the establishment of a TPM3 monoclonal stable transfected PANC-1 cell line and the experiment of the EMT occurrence in human pancreatic cancer. Onco Targets Ther. 2019;12:5577-5587 pubmed 出版商
Choi H, Kwon K, Han S, Kang S, Choi E, Kim A, et al. PPE39 of the Mycobacterium tuberculosis strain Beijing/K induces Th1-cell polarization through dendritic cell maturation. J Cell Sci. 2019;132: pubmed 出版商
Jeong K, Ryu I, Park J, Hwang H, Ha H, Park Y, et al. Staufen1 and UPF1 exert opposite actions on the replacement of the nuclear cap-binding complex by eIF4E at the 5' end of mRNAs. Nucleic Acids Res. 2019;47:9313-9328 pubmed 出版商
Wu J, Yang B, Zhang Y, Feng X, He B, Xie H, et al. miR-424-5p represses the metastasis and invasion of intrahepatic cholangiocarcinoma by targeting ARK5. Int J Biol Sci. 2019;15:1591-1599 pubmed 出版商
Li H, Li J, Zhang X, Li J, Xi C, Wang W, et al. 23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9. Acta Pharmacol Sin. 2019;: pubmed 出版商
Reed E, Ard S, La J, Park C, Culligan L, Fredberg J, et al. Anti-fibrotic effects of tannic acid through regulation of a sustained TGF-beta receptor signaling. Respir Res. 2019;20:168 pubmed 出版商
Guan J, Zhou W, Hafner M, Blake R, Chalouni C, Chen I, et al. Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility. Cell. 2019;178:949-963.e18 pubmed 出版商
Raggi C, Fiaccadori K, Pastore M, Correnti M, Piombanti B, Forti E, et al. Antitumor Activity of a Novel Fibroblast Growth Factor Receptor Inhibitor for Intrahepatic Cholangiocarcinoma. Am J Pathol. 2019;189:2090-2101 pubmed 出版商
Nishino K, Watanabe S, Shijie J, Murata Y, Oiwa K, Komine O, et al. Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1-Akt signaling pathway. Acta Neuropathol Commun. 2019;7:118 pubmed 出版商
Rayes R, Mouhanna J, Nicolau I, Bourdeau F, Giannias B, Rousseau S, et al. Primary tumors induce neutrophil extracellular traps with targetable metastasis promoting effects. JCI Insight. 2019;5: pubmed 出版商
Lee J, Kosowicz J, Hayward S, Desai P, Stone J, Lee J, et al. Pharmacologic Activation of Lytic Epstein-Barr Virus Gene Expression without Virion Production. J Virol. 2019;93: pubmed 出版商
Li D, Fu S, Wu Z, Yang W, Ru Y, SHU H, et al. DDX56 inhibits type I interferon by disrupting assembly of IRF3-IPO5 to inhibit IRF3 nucleus import. J Cell Sci. 2019;133: pubmed 出版商
Kobayashi M, Benakis C, Anderson C, Moore M, Poon C, Uekawa K, et al. AGO CLIP Reveals an Activated Network for Acute Regulation of Brain Glutamate Homeostasis in Ischemic Stroke. Cell Rep. 2019;28:979-991.e6 pubmed 出版商
Tsutsumi T, Nagaoka T, Yoshida T, Wang L, Kuriyama S, Suzuki Y, et al. Nintedanib ameliorates experimental pulmonary arterial hypertension via inhibition of endothelial mesenchymal transition and smooth muscle cell proliferation. PLoS ONE. 2019;14:e0214697 pubmed 出版商
Akhter M, Uddin M, Barabutis N. Unfolded protein response regulates P53 expression in the pulmonary endothelium. J Biochem Mol Toxicol. 2019;33:e22380 pubmed 出版商
Yang X, Wang X, Song Y, Zhou P, Li D, Zhang C, et al. Chimpanzee adenoviral vector prime-boost regimen elicits potent immune responses against Ebola virus in mice and rhesus macaques. Emerg Microbes Infect. 2019;8:1086-1097 pubmed 出版商
Qi Y, Montague P, Loney C, Campbell C, Shafie I, Anderson T, et al. In vitro evidence consistent with an interaction between wild-type and mutant SOD1 protein associated with canine degenerative myelopathy. Eur J Neurosci. 2019;50:3896-3905 pubmed 出版商
Baumann J, Huang S, Gassmann M, Tsao C, Ogunshola O. Furin inhibition prevents hypoxic and TGFβ-mediated blood-brain barrier disruption. Exp Cell Res. 2019;383:111503 pubmed 出版商
Liu C, Yang P, Wang T, Huang S, Kuo Y, Cheng S. PGC1α downregulation and glycolytic phenotype in thyroid cancer. J Cancer. 2019;10:3819-3829 pubmed 出版商
Carcolé M, Kummer S, Gonçalves L, Zamanillo D, Merlos M, Dickenson A, et al. Sigma-1 receptor modulates neuroinflammation associated with mechanical hypersensitivity and opioid tolerance in a mouse model of osteoarthritis pain. Br J Pharmacol. 2019;176:3939-3955 pubmed 出版商
Gerlach S, Sander M, Song S, Herranz H. The miRNA bantam regulates growth and tumorigenesis by repressing the cell cycle regulator tribbles. Life Sci Alliance. 2019;2: pubmed 出版商
Pessolano E, Belvedere R, Bizzarro V, Franco P, Marco I, Petrella F, et al. Annexin A1 Contained in Extracellular Vesicles Promotes the Activation of Keratinocytes by Mesoglycan Effects: An Autocrine Loop Through FPRs. Cells. 2019;8: pubmed 出版商
Menéndez Menéndez J, Hermida Prado F, Granda Díaz R, Gonzalez A, Garcia Pedrero J, Del Río Ibisate N, et al. Deciphering the Molecular Basis of Melatonin Protective Effects on Breast Cells Treated with Doxorubicin: TWIST1 a Transcription Factor Involved in EMT and Metastasis, a Novel Target of Melatonin. Cancers (Basel). 2019;11: pubmed 出版商
Wu X, Zhao G, He Y, Wang W, Yang C, Zhang J. Pharmacological mechanisms of the anticancer action of sodium selenite against peritoneal cancer in mice. Pharmacol Res. 2019;147:104360 pubmed 出版商
Wang Y, Wang Y, Wang N, You L, Long F, Shao C, et al. Poly(ADP‑ribose) polymerase 1/2 inhibitors decrease the ubiquitination of ALC1 mediated by CHFR in breast cancer. Oncol Rep. 2019;42:1467-1474 pubmed 出版商
Ae Yoon N, Park J, Yeon Jeong J, Rashidova N, Ryu J, Seob Roh G, et al. Anti-obesity Activity of Ethanol Extract from Bitter Melon in Mice Fed High-Fat Diet. Dev Reprod. 2019;23:129-138 pubmed 出版商
Zhovmer A, Tabdanov E, Miao H, Wen H, Chen J, Luo X, et al. The role of nonmuscle myosin 2A and 2B in the regulation of mesenchymal cell contact guidance. Mol Biol Cell. 2019;30:1961-1973 pubmed 出版商
Erdem M, Möckel D, Jumpertz S, John C, Fragoulis A, Rudolph I, et al. Macrophages protect against loss of adipose tissue during cancer cachexia. J Cachexia Sarcopenia Muscle. 2019;10:1128-1142 pubmed 出版商
Xie X, Lin J, Zhong Y, Fu M, Tang A. FGFR3S249C mutation promotes chemoresistance by activating Akt signaling in bladder cancer cells. Exp Ther Med. 2019;18:1226-1234 pubmed 出版商
Schult P, Nattermann M, Lauber C, Seitz S, Lohmann V. Evidence for Internal Initiation of RNA Synthesis by the Hepatitis C Virus RNA-Dependent RNA Polymerase NS5B In Cellulo. J Virol. 2019;93: pubmed 出版商
Wang X, Obeidat M, Li L, Pasarj P, Aburahess S, Holmes C, et al. TIMAP inhibits endothelial myosin light chain phosphatase by competing with MYPT1 for the catalytic protein phosphatase 1 subunit PP1cβ. J Biol Chem. 2019;294:13280-13291 pubmed 出版商
Senapati P, Kato H, Lee M, Leung A, Thai C, Sanchez A, et al. Hyperinsulinemia promotes aberrant histone acetylation in triple-negative breast cancer. Epigenetics Chromatin. 2019;12:44 pubmed 出版商
Li L, Ruan X, Wen C, Chen P, Liu W, Zhu L, et al. The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019;28:698-711.e5 pubmed 出版商
Fukumoto T, Fatkhutdinov N, Zundell J, Tcyganov E, Nacarelli T, Karakashev S, et al. HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer. Cancer Res. 2019;79:5482-5489 pubmed 出版商
Hart M, Walch Rückheim B, Krammes L, Kehl T, Rheinheimer S, Tänzer T, et al. miR-34a as hub of T cell regulation networks. J Immunother Cancer. 2019;7:187 pubmed 出版商
Chen H, Crosley P, Azad A, Gupta N, Gokul N, Xu Z, et al. RUNX3 Promotes the Tumorigenic Phenotype in KGN, a Human Granulosa Cell Tumor-Derived Cell Line. Int J Mol Sci. 2019;20: pubmed 出版商
Dedoni S, Marras L, Olianas M, Ingianni A, Onali P. Downregulation of TrkB Expression and Signaling by Valproic Acid and Other Histone Deacetylase Inhibitors. J Pharmacol Exp Ther. 2019;370:490-503 pubmed 出版商
Hata T, Rajabi H, Yamamoto M, Jin C, Ahmad R, Zhang Y, et al. Targeting MUC1-C Inhibits TWIST1 Signaling in Triple-Negative Breast Cancer. Mol Cancer Ther. 2019;18:1744-1754 pubmed 出版商
Sharma A, Oonthonpan L, Sheldon R, Rauckhorst A, Zhu Z, Tompkins S, et al. Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness. elife. 2019;8: pubmed 出版商
Mohammad G, Duraisamy A, Kowluru A, Kowluru R. Functional Regulation of an Oxidative Stress Mediator, Rac1, in Diabetic Retinopathy. Mol Neurobiol. 2019;56:8643-8655 pubmed 出版商
Martinez Hervas S, SÁnchez GarcÍa V, Herrero Cervera A, Vinue A, Real J, Ascaso J, et al. Type 1 diabetic mellitus patients with increased atherosclerosis risk display decreased CDKN2A/2B/2BAS gene expression in leukocytes. J Transl Med. 2019;17:222 pubmed 出版商
Lyu X, Chastain M, Chai W. Genome-wide mapping and profiling of γH2AX binding hotspots in response to different replication stress inducers. BMC Genomics. 2019;20:579 pubmed 出版商
García Ruiz I, Blanes Ruiz N, Rada P, Pardo V, Ruiz L, Blas García A, et al. Protein tyrosine phosphatase 1b deficiency protects against hepatic fibrosis by modulating nadph oxidases. Redox Biol. 2019;26:101263 pubmed 出版商
Pickel C, Günter J, Ruiz Serrano A, Spielmann P, Fabrizio J, Wolski W, et al. Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1. Redox Biol. 2019;26:101265 pubmed 出版商
Niklasson M, Bergström T, Jarvius M, Sundström A, Nyberg F, Haglund C, et al. Mesenchymal transition and increased therapy resistance of glioblastoma cells is related to astrocyte reactivity. J Pathol. 2019;249:295-307 pubmed 出版商
Bruntz R, Belshoff A, Zhang Y, Macedo J, Higashi R, Lane A, et al. Inhibition of Anaplerotic Glutaminolysis Underlies Selenite Toxicity in Human Lung Cancer. Proteomics. 2019;19:e1800486 pubmed 出版商
Wang M, Fer N, Galeas J, Collisson E, Kim S, Sharib J, et al. Blockade of leukemia inhibitory factor as a therapeutic approach to KRAS driven pancreatic cancer. Nat Commun. 2019;10:3055 pubmed 出版商
Zhou Z, Xu J, Bao X, Shi J, Liu B, Chen Y, et al. Nuclear Nrf2 Activity in Laryngeal Carcinoma is Regulated by SENP3 After Cisplatin-Induced Reactive Oxygen Species Stress. J Cancer. 2019;10:3427-3434 pubmed 出版商
Martín Segura A, Casadomé Perales Á, Fazzari P, Mas J, Artigas L, Valls R, et al. Aging Increases Hippocampal DUSP2 by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism. Front Neurol. 2019;10:675 pubmed 出版商
Gao G, Sheng Y, Yang H, Chua B, Xu L. DFCP1 associates with lipid droplets. Cell Biol Int. 2019;: pubmed 出版商
Ohsugi T, Yamaguchi K, Zhu C, Ikenoue T, Takane K, Shinozaki M, et al. Anti-apoptotic effect by the suppression of IRF1 as a downstream of Wnt/β-catenin signaling in colorectal cancer cells. Oncogene. 2019;38:6051-6064 pubmed 出版商
Borghese F, Sorgeloos F, Cesaro T, Michiels T. The leader protein of Theiler's virus prevents the activation of PKR by dsRNA. J Virol. 2019;: pubmed 出版商
Saraswati S, Marrow S, Watch L, Young P. Identification of a pro-angiogenic functional role for FSP1-positive fibroblast subtype in wound healing. Nat Commun. 2019;10:3027 pubmed 出版商
Xue D, Zhang Y, Wang Y, Wang J, An F, Sun X, et al. Quantitative proteomic analysis of sperm in unexplained recurrent pregnancy loss. Reprod Biol Endocrinol. 2019;17:52 pubmed 出版商
Zyner K, Mulhearn D, Adhikari S, Mart nez Cuesta S, Di Antonio M, Erard N, et al. Genetic interactions of G-quadruplexes in humans. elife. 2019;8: pubmed 出版商
Urano Y, Ho Vo D, Hirofumi A, Noguchi N. 24(S)-Hydroxycholesterol induces ER dysfunction-mediated unconventional cell death. Cell Death Discov. 2019;5:113 pubmed 出版商
Maitland M, Onea G, Chiasson C, Wang X, Ma J, Moor S, et al. The mammalian CTLH complex is an E3 ubiquitin ligase that targets its subunit muskelin for degradation. Sci Rep. 2019;9:9864 pubmed 出版商
Zhang X, Espinosa B, Saei A, D Arcy P, Zubarev R, Linder S. Oxidative Stress Induced by the Deubiquitinase Inhibitor b-AP15 Is Associated with Mitochondrial Impairment. Oxid Med Cell Longev. 2019;2019:1659468 pubmed 出版商
Boulias K, Toczydłowska Socha D, Hawley B, Liberman N, Takashima K, Zaccara S, et al. Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome. Mol Cell. 2019;: pubmed 出版商
Epp A, Ebert S, Sanchez Arias J, Wicki Stordeur L, Boyce A, Swayne L. A novel motif in the proximal C-terminus of Pannexin 1 regulates cell surface localization. Sci Rep. 2019;9:9721 pubmed 出版商
Wang X, Peng P, Pan Z, Fang Z, Lu W, Liu X. Psoralen inhibits malignant proliferation and induces apoptosis through triggering endoplasmic reticulum stress in human SMMC7721 hepatoma cells. Biol Res. 2019;52:34 pubmed 出版商
Auburger G, Gispert S, Torres Odio S, Jendrach M, Brehm N, Canet Pons J, et al. SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. Int J Mol Sci. 2019;20: pubmed 出版商
Benyelles M, Episkopou H, O Donohue M, Kermasson L, Frange P, Poulain F, et al. Impaired telomere integrity and rRNA biogenesis in PARN-deficient patients and knock-out models. EMBO Mol Med. 2019;11:e10201 pubmed 出版商
Jiang Y, Li C, Wu Q, An P, Huang L, Wang J, et al. Iron-dependent histone 3 lysine 9 demethylation controls B cell proliferation and humoral immune responses. Nat Commun. 2019;10:2935 pubmed 出版商
Szego E, Dominguez Meijide A, Gerhardt E, König A, Koss D, Li W, et al. Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies. Cell Rep. 2019;28:65-77.e6 pubmed 出版商
Tower Gilchrist C, Zlatic S, Yu D, Chang Q, Wu H, Lin X, et al. Adaptor protein-3 complex is required for Vangl2 trafficking and planar cell polarity of the inner ear. Mol Biol Cell. 2019;:mbcE16080592 pubmed 出版商
Jia Y, Reddy M, Das S, Oh H, Abdollahi M, Yuan H, et al. Dysregulation of histone H3 lysine 27 trimethylation in transforming growth factor-β1-induced gene expression in mesangial cells and diabetic kidney. J Biol Chem. 2019;294:12695-12707 pubmed 出版商
Liu W, Tang Q, Zhang Q, Hu C, Huang J, Sheng F, et al. Lycorine Induces Mitochondria-Dependent Apoptosis in Hepatoblastoma HepG2 Cells Through ROCK1 Activation. Front Pharmacol. 2019;10:651 pubmed 出版商
Tameire F, Verginadis I, Leli N, Polte C, Conn C, Ojha R, et al. ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression. Nat Cell Biol. 2019;21:889-899 pubmed 出版商
Kim H, Kim Y, Hong S. Astaxanthin suppresses the metastasis of colon cancer by inhibiting the MYC-mediated downregulation of microRNA-29a-3p and microRNA-200a. Sci Rep. 2019;9:9457 pubmed 出版商
Aripaka K, Gudey S, Zang G, Schmidt A, Åhrling S, Österman L, et al. TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer. EBioMedicine. 2019;: pubmed 出版商
Nanni M, Ranieri D, Persechino F, Torrisi M, Belleudi F. The Aberrant Expression of the Mesenchymal Variant of FGFR2 in the Epithelial Context Inhibits Autophagy. Cells. 2019;8: pubmed 出版商
Matsui T, Chiyo T, Kobara H, Fujihara S, Fujita K, Namima D, et al. Telmisartan Inhibits Cell Proliferation and Tumor Growth of Esophageal Squamous Cell Carcinoma by Inducing S-Phase Arrest In Vitro and In Vivo. Int J Mol Sci. 2019;20: pubmed 出版商
Wang X, Zhan E, Lu G, Mu Q, Zhang T, Yang N. Sphingosine-1-Phosphate Improves the Biological Features of Mouse Bone Marrow-Derived EPCs Partially through PI3K/AKT/eNOS/NO Pathway. Molecules. 2019;24: pubmed 出版商
Sant Ana C, Antunes P, Reis T, Vaz Tostes M, Meira E, Costa N. Bioaccessibility and bioavailability of iron in biofortified germinated cowpea. J Sci Food Agric. 2019;99:6287-6295 pubmed 出版商
Peng Y, Li L, Zhang X, Xie M, Yang C, Tu S, et al. Fluorofenidone affects hepatic stellate cell activation in hepatic fibrosis by targeting the TGF-β1/Smad and MAPK signaling pathways. Exp Ther Med. 2019;18:41-48 pubmed 出版商
Gomez Puerto M, van Zuijen I, Huang C, Szulcek R, Pan X, van Dinther M, et al. Autophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertension. J Pathol. 2019;249:356-367 pubmed 出版商
Sumi N, Ctortecka C, Hu Q, Bryant A, Fang B, Remsing Rix L, et al. Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets. Cell Chem Biol. 2019;26:1240-1252.e11 pubmed 出版商
Pyo J, Ahn S, Jin S, An S, Lee E, Choi J, et al. Keratinocyte-derived IL-36γ plays a role in hydroquinone-induced chemical leukoderma through inhibition of melanogenesis in human epidermal melanocytes. Arch Toxicol. 2019;93:2307-2320 pubmed 出版商
Huang J, Zhao L, Fan Y, Liao L, Ma P, Xiao G, et al. The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression. Nat Commun. 2019;10:2876 pubmed 出版商
Xie X, Lin J, Liu J, Huang M, Zhong Y, Liang B, et al. A novel lncRNA NR4A1AS up-regulates orphan nuclear receptor NR4A1 expression by blocking UPF1-mediated mRNA destabilization in colorectal cancer. Clin Sci (Lond). 2019;133:1457-1473 pubmed 出版商
Zhu L, Wei Q, Qi Y, Ruan X, Wu F, Li L, et al. PTB-AS, a Novel Natural Antisense Transcript, Promotes Glioma Progression by Improving PTBP1 mRNA Stability with SND1. Mol Ther. 2019;27:1621-1637 pubmed 出版商
Lee H, Jung J, Moon A, Kang H, Cho H. Antitumor and Anti-Invasive Effect of Apigenin on Human Breast Carcinoma through Suppression of IL-6 Expression. Int J Mol Sci. 2019;20: pubmed 出版商
Xiao R, Chen J, Liang Z, Luo D, Chen G, Lu Z, et al. Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription. Cell. 2019;178:107-121.e18 pubmed 出版商
Xia X, Liu Y, Hodgson A, Xu D, Guo W, Yu H, et al. EspF is crucial for Citrobacter rodentium-induced tight junction disruption and lethality in immunocompromised animals. PLoS Pathog. 2019;15:e1007898 pubmed 出版商
Majerník M, Jendželovský R, Babinčák M, Kosuth J, Sevc J, Tonelli Gombalová Z, et al. Novel Insights into the Effect of Hyperforin and Photodynamic Therapy with Hypericin on Chosen Angiogenic Factors in Colorectal Micro-Tumors Created on Chorioallantoic Membrane. Int J Mol Sci. 2019;20: pubmed 出版商
Georg I, Díaz Barreiro A, Morell M, Pey A, Alarcon Riquelme M. BANK1 interacts with TRAF6 and MyD88 in innate immune signaling in B cells. Cell Mol Immunol. 2019;: pubmed 出版商
Hua X, Huang M, Deng X, Xu J, Luo Y, Xie Q, et al. The inhibitory effect of compound ChlA-F on human bladder cancer cell invasion can be attributed to its blockage of SOX2 protein. Cell Death Differ. 2019;: pubmed 出版商
Li J, Ayoub A, Xiu Y, Yin X, Sanders J, Mesfin A, et al. TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis. Nat Commun. 2019;10:2795 pubmed 出版商
Buttarelli M, Babini G, Raspaglio G, Filippetti F, Battaglia A, Ciucci A, et al. A combined ANXA2-NDRG1-STAT1 gene signature predicts response to chemoradiotherapy in cervical cancer. J Exp Clin Cancer Res. 2019;38:279 pubmed 出版商
Koyama S, Horie T, Nishino T, Baba O, Sowa N, Miyasaka Y, et al. Identification of Differential Roles of MicroRNA-33a and -33b During Atherosclerosis Progression With Genetically Modified Mice. J Am Heart Assoc. 2019;8:e012609 pubmed 出版商
Yang S, Liu J, Wang C, Lin Y, Tsai S, Chen W, et al. Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2. FASEB J. 2019;:fj201800220RR pubmed 出版商
Tassone E, Bradaschia Correa V, Xiong X, Sastre Perona A, Josephson A, Khodadadi Jamayran A, et al. KLF4 as a rheostat of osteolysis and osteogenesis in prostate tumors in the bone. Oncogene. 2019;38:5766-5777 pubmed 出版商
Navas Madroñal M, Rodriguez C, Kassan M, Fite J, Escudero J, Cañes L, et al. Enhanced endoplasmic reticulum and mitochondrial stress in abdominal aortic aneurysm. Clin Sci (Lond). 2019;133:1421-1438 pubmed 出版商
Domingo Vidal M, Whitaker Menezes D, Martos Rus C, Tassone P, Snyder C, Tuluc M, et al. Cigarette Smoke Induces Metabolic Reprogramming of the Tumor Stroma in Head and Neck Squamous Cell Carcinoma. Mol Cancer Res. 2019;17:1893-1909 pubmed 出版商
Acharya S, Yao J, Li P, Zhang C, Lowery F, Zhang Q, et al. Sphingosine-kinase-1 signaling promotes metastasis of triple-negative breast cancer. Cancer Res. 2019;: pubmed 出版商
Aquino Galvez A, Gonzalez Avila G, Jiménez Sánchez L, Maldonado Martínez H, Cisneros J, Toscano Marquez F, et al. Dysregulated expression of hypoxia-inducible factors augments myofibroblasts differentiation in idiopathic pulmonary fibrosis. Respir Res. 2019;20:130 pubmed 出版商
Li Q, Li Q, Jia J, Sun Q, Zhou H, Jin W, et al. Baicalein Exerts Neuroprotective Effects in FeCl3-Induced Posttraumatic Epileptic Seizures via Suppressing Ferroptosis. Front Pharmacol. 2019;10:638 pubmed 出版商
Tenjin Y, Kudoh S, Kubota S, Yamada T, Matsuo A, Sato Y, et al. Ascl1-induced Wnt11 regulates neuroendocrine differentiation, cell proliferation, and E-cadherin expression in small-cell lung cancer and Wnt11 regulates small-cell lung cancer biology. Lab Invest. 2019;: pubmed 出版商
Sebti S, Kazi A, Xiang S, Yang H, Chen L, Kennedy P, et al. Dual farnesyl and geranylgeranyl transferase inhibitor thwarts mutant KRAS-driven patient-derived pancreatic tumors. Clin Cancer Res. 2019;: pubmed 出版商
Huaman J, Naidoo M, Zang X, Ogunwobi O. Fibronectin Regulation of Integrin B1 and SLUG in Circulating Tumor Cells. Cells. 2019;8: pubmed 出版商
Guo Z, Zhao K, Feng X, Yan D, Yao R, Chen Y, et al. mTORC2 Regulates Lipogenic Gene Expression through PPARγ to Control Lipid Synthesis in Bovine Mammary Epithelial Cells. Biomed Res Int. 2019;2019:5196028 pubmed 出版商
Pawelec K, Yoon C, Giger R, Sakamoto J. Engineering a platform for nerve regeneration with direct application to nerve repair technology. Biomaterials. 2019;216:119263 pubmed 出版商
Besnier M, Shantikumar S, Anwar M, Dixit P, Chamorro Jorganes A, Sweaad W, et al. miR-15a/-16 Inhibit Angiogenesis by Targeting the Tie2 Coding Sequence: Therapeutic Potential of a miR-15a/16 Decoy System in Limb Ischemia. Mol Ther Nucleic Acids. 2019;17:49-62 pubmed 出版商
Yeste Velasco M, Guo T, Mao X, Stankiewicz E, Scandura G, Li H, et al. The potential of brentuximab vedotin, alone or in combination with current clinical therapies, in the treatment of testicular germ cell tumors. Am J Cancer Res. 2019;9:855-871 pubmed
Yoon C, Till J, Cho S, Chang K, Lin J, Huang C, et al. KRAS activation in gastric adenocarcinoma stimulates epithelial-to-mesenchymal transition to cancer stem-like cells and promotes metastasis. Mol Cancer Res. 2019;: pubmed 出版商
Lee W, Jeong Y, Park J, Lee C, Yun N, Lee D, et al. Water-Soluble Extract from Actinidia arguta (Siebold & Zucc.) Planch. ex Miq. and Perilla frutescens (L.) Britton, ACTPER, Ameliorates a Dry Skin-Induced Itch in a Mice Model and Promotes Filaggrin Expression by Activating the AhR Signaling in Ha. Nutrients. 2019;11: pubmed 出版商
Lee J, Cortese M, Haselmann U, Tabata K, Romero Brey I, Funaya C, et al. Spatiotemporal Coupling of the Hepatitis C Virus Replication Cycle by Creating a Lipid Droplet- Proximal Membranous Replication Compartment. Cell Rep. 2019;27:3602-3617.e5 pubmed 出版商
Phung B, Ciesla M, Sanna A, Guzzi N, Beneventi G, Cao Thi Ngoc P, et al. The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma. Cell Rep. 2019;27:3573-3586.e7 pubmed 出版商
Grill S, Bisht K, Tesmer V, Shami A, Hammoud S, Nandakumar J. Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells. Cell Rep. 2019;27:3511-3521.e7 pubmed 出版商
Kong D, He M, Yang L, Zhou R, Yan Y, Liang Y, et al. MiR-17 and miR-19 cooperatively promote skeletal muscle cell differentiation. Cell Mol Life Sci. 2019;: pubmed 出版商
Cheng J, Tsai W, Liu P, Goan Y, Lin C, Tseng H, et al. The MAP3K7-mTOR Axis Promotes the Proliferation and Malignancy of Hepatocellular Carcinoma Cells. Front Oncol. 2019;9:474 pubmed 出版商
Marycz K, Houston J, Weiss C, Rocken M, Kornicka K. 5-Azacytidine and Resveratrol Enhance Chondrogenic Differentiation of Metabolic Syndrome-Derived Mesenchymal Stem Cells by Modulating Autophagy. Oxid Med Cell Longev. 2019;2019:1523140 pubmed 出版商
McCormick J, King K, Dokladny K, Mermier C. Effect of Acute Aerobic Exercise and Rapamycin Treatment on Autophagy in Peripheral Blood Mononuclear Cells of Adults With Prediabetes. Can J Diabetes. 2019;: pubmed 出版商
Wu C, Cui X, Huang L, Shang X, Wu B, Wang N, et al. IRTKS Promotes Insulin Signaling Transduction through Inhibiting SHIP2 Phosphatase Activity. Int J Mol Sci. 2019;20: pubmed 出版商
Hu Q, Myers M, Fang W, Yao M, Brummer G, Hawj J, et al. Role of ALDH1A1 and HTRA2 expression to CCL2/CCR2 mediated breast cancer cell growth and invasion. Biol Open. 2019;: pubmed 出版商
Cao X, Liu L, Yuan Q, Li X, Cui Y, Ren K, et al. Isovitexin reduces carcinogenicity and stemness in hepatic carcinoma stem-like cells by modulating MnSOD and FoxM1. J Exp Clin Cancer Res. 2019;38:264 pubmed 出版商
Yu Taeger L, Stricker Shaver J, Arnold K, Bambynek Dziuk P, Novati A, Singer E, et al. Intranasal Administration of Mesenchymal Stem Cells Ameliorates the Abnormal Dopamine Transmission System and Inflammatory Reaction in the R6/2 Mouse Model of Huntington Disease. Cells. 2019;8: pubmed 出版商
Tran P, Wang T, Yin W, Tran T, Barua H, Zhang Y, et al. Development of a nanoamorphous exosomal delivery system as an effective biological platform for improved encapsulation of hydrophobic drugs. Int J Pharm. 2019;: pubmed 出版商
Xie R, Yang Y, Zhang H, Liu H, Guo J, Qin H, et al. c-Myb and its Effector COX-2 as an Indicator Associated with Prognosis and Therapeutic Outcome in Colorectal Cancer. J Cancer. 2019;10:1601-1610 pubmed 出版商
Lin Y, Wu C, Wang X, Liu S, Zhao K, Kemper T, et al. Glucosamine promotes hepatitis B virus replication through its dual effects in suppressing autophagic degradation and inhibiting MTORC1 signaling. Autophagy. 2019;:1-14 pubmed 出版商
Alwhaibi A, Verma A, Artham S, Adil M, Somanath P. Nodal pathway activation due to Akt1 suppression is a molecular switch for prostate cancer cell epithelial-to-mesenchymal transition and metastasis. Biochem Pharmacol. 2019;168:1-13 pubmed 出版商
Lee Y, Lim S, Lee B, Kang I, Yeo E. Compound C Inhibits B16-F1 Tumor Growth in a Syngeneic Mouse Model Via the Blockage of Cell Cycle Progression and Angiogenesis. Cancers (Basel). 2019;11: pubmed 出版商
Pervolaraki K, Guo C, Albrecht D, Boulant S, Stanifer M. Type-Specific Crosstalk Modulates Interferon Signaling in Intestinal Epithelial Cells. J Interferon Cytokine Res. 2019;39:650-660 pubmed 出版商
Busceti C, Ferese R, Bucci D, Ryskalin L, Gambardella S, Madonna M, et al. Corticosterone Upregulates Gene and Protein Expression of Catecholamine Markers in Organotypic Brainstem Cultures. Int J Mol Sci. 2019;20: pubmed 出版商
Zhang X, Kumstel S, Jiang K, Meng S, Gong P, Vollmar B, et al. LW6 enhances chemosensitivity to gemcitabine and inhibits autophagic flux in pancreatic cancer. J Adv Res. 2019;20:9-21 pubmed 出版商
Gonçalves N, Mohseni S, El Soury M, Ulrichsen M, Richner M, Xiao J, et al. Peripheral Nerve Regeneration Is Independent From Schwann Cell p75NTR Expression. Front Cell Neurosci. 2019;13:235 pubmed 出版商
Doi M, Shimatani H, Atobe Y, Murai I, Hayashi H, Takahashi Y, et al. Non-coding cis-element of Period2 is essential for maintaining organismal circadian behaviour and body temperature rhythmicity. Nat Commun. 2019;10:2563 pubmed 出版商
Chiramel A, Meyerson N, McNally K, Broeckel R, Montoya V, Méndez Solís O, et al. TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation. Cell Rep. 2019;27:3269-3283.e6 pubmed 出版商
Cooke A, Schwarzl T, Huppertz I, Kramer G, Mantas P, Alleaume A, et al. The RNA-Binding Protein YBX3 Controls Amino Acid Levels by Regulating SLC mRNA Abundance. Cell Rep. 2019;27:3097-3106.e5 pubmed 出版商
Wang Y, Tatham M, Schmidt Heck W, Swann C, Singh Dolt K, Meseguer Ripolles J, et al. Multiomics Analyses of HNF4α Protein Domain Function during Human Pluripotent Stem Cell Differentiation. iScience. 2019;16:206-217 pubmed 出版商
Lee G, Kim J, Kwon S, Stein M, Hong J, Nagaya N, et al. Dihydrotestosterone Increases Cytotoxic Activity of Macrophages on Prostate Cancer Cells via TRAIL. Endocrinology. 2019;160:2049-2060 pubmed 出版商
Feng J, Dong C, Long Y, Mai L, Ren M, Li L, et al. Elevated Kallikrein-binding protein in diabetes impairs wound healing through inducing macrophage M1 polarization. Cell Commun Signal. 2019;17:60 pubmed 出版商
Bae Y, Kim A, Cho C, Kim D, Jung H, Kim S, et al. TTYH1 and TTYH2 Serve as LRRC8A-Independent Volume-Regulated Anion Channels in Cancer Cells. Cells. 2019;8: pubmed 出版商
Pellecchia S, Sepe R, Federico A, Cuomo M, Credendino S, Pisapia P, et al. The Metallophosphoesterase-Domain-Containing Protein 2 (MPPED2) Gene Acts as Tumor Suppressor in Breast Cancer. Cancers (Basel). 2019;11: pubmed 出版商
Byun M, Kim C, Lee H, Choi J, Lee S. Repurposing of ginseng extract as topoisomerase I inhibitor based on the comparative analysis of gene expression patterns. Phytochemistry. 2019;164:223-227 pubmed 出版商
Hung K, Liao W, Pao H, Wu S, Huang K, Chu S. Targeting F-Box Protein Fbxo3 Attenuates Lung Injury Induced by Ischemia-Reperfusion in Rats. Front Pharmacol. 2019;10:583 pubmed 出版商
MacKeil J, Brzezinska P, Burke Kleinman J, Theilmann A, Nicol C, Ormiston M, et al. Phosphodiesterase 3B (PDE3B) antagonizes the anti-angiogenic actions of PKA in human and murine endothelial cells. Cell Signal. 2019;62:109342 pubmed 出版商
Zheng Y, Yu Y, Xie K, Yuan Y, Chen Y, Wang C, et al. Electroacupuncture alleviates morphine‑induced hyperalgesia by regulating spinal CB1 receptors and ERK1/2 activity. Mol Med Rep. 2019;20:1113-1120 pubmed 出版商
Leng H, Zhang X, Wang Q, Luan X, Sun X, Guo F, et al. Regulation of stress-induced gastric ulcers via central oxytocin and a potential mechanism through the VTA-NAc dopamine pathway. Neurogastroenterol Motil. 2019;31:e13655 pubmed 出版商
Benyelles M, Episkopou H, O Donohue M, Kermasson L, Frange P, Poulain F, et al. Impaired telomere integrity and rRNA biogenesis in PARN-deficient patients and knock-out models. EMBO Mol Med. 2019;: pubmed 出版商
Zhang C, Fondufe Mittendorf Y, Wang C, Chen J, Cheng Q, Zhou D, et al. Latexin regulation by HMGB2 is required for hematopoietic stem cell maintenance. Haematologica. 2019;: pubmed 出版商
Coquenlorge S, Yin W, Yung T, Pan J, Zhang X, Mo R, et al. GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis. Cell Rep. 2019;27:3006-3018.e4 pubmed 出版商
Mikdache A, Fontenas L, Albadri S, Revenu C, Loisel Duwattez J, Lesport E, et al. Elmo1 function, linked to Rac1 activity, regulates peripheral neuronal numbers and myelination in zebrafish. Cell Mol Life Sci. 2019;: pubmed 出版商
Chang H, Liu P, Tsai W, Hu W, Hu Y, Yang H, et al. Xanthium strumarium Fruit Extract Inhibits ATG4B and Diminishes the Proliferation and Metastatic Characteristics of Colorectal Cancer Cells. Toxins (Basel). 2019;11: pubmed 出版商
Zeltz C, Alam J, Liu H, Erusappan P, Hoschuetzky H, Molven A, et al. α11β1 Integrin is Induced in a Subset of Cancer-Associated Fibroblasts in Desmoplastic Tumor Stroma and Mediates In Vitro Cell Migration. Cancers (Basel). 2019;11: pubmed 出版商
Rizzini L, Levine D, Perelis M, Bass J, Peek C, Pagano M. Cryptochromes-Mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism. Curr Biol. 2019;29:1954-1962.e4 pubmed 出版商
Hammerschmidt P, Ostkotte D, Nolte H, Gerl M, Jais A, Brunner H, et al. CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity. Cell. 2019;177:1536-1552.e23 pubmed 出版商
Miarka L, Hauser C, Helm O, Holdhof D, Beckinger S, Egberts J, et al. The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection. Cancers (Basel). 2019;11: pubmed 出版商
Chiyo T, Fujita K, Iwama H, Fujihara S, Tadokoro T, Ohura K, et al. Galectin-9 Induces Mitochondria-Mediated Apoptosis of Esophageal Cancer In Vitro and In Vivo in a Xenograft Mouse Model. Int J Mol Sci. 2019;20: pubmed 出版商
Feng C, Chen N, Wen Z, Yang W, Kuo H, Sung P, et al. In Vitro and In Vivo Neuroprotective Effects of Stellettin B Through Anti-Apoptosis and the Nrf2/HO-1 Pathway. Mar Drugs. 2019;17: pubmed 出版商
Cortese M, Kumar A, Matula P, Kaderali L, Scaturro P, Erfle H, et al. Reciprocal Effects of Fibroblast Growth Factor Receptor Signaling on Dengue Virus Replication and Virion Production. Cell Rep. 2019;27:2579-2592.e6 pubmed 出版商
Tang J, Shu C, Wang C, Wang S, Chang M, Lin L, et al. Sulfonyl chromen-4-ones (CHW09) shows an additive effect to inhibit cell growth of X-ray irradiated oral cancer cells, involving apoptosis and ROS generation. Int J Radiat Biol. 2019;95:1226-1235 pubmed 出版商
Baek J, Vignesh A, Son H, Lee D, Roh G, Kang S, et al. Glutamine Supplementation Ameliorates Chronic Stress-induced Reductions in Glutamate and Glutamine Transporters in the Mouse Prefrontal Cortex. Exp Neurobiol. 2019;28:270-278 pubmed 出版商
Mandl M, Wagner S, Hatzmann F, Mitterberger Vogt M, Zwierzina M, Mattesich M, et al. Sprouty1 is a weight-loss target gene in human adipose stem/progenitor cells that is mandatory for the initiation of adipogenesis. Cell Death Dis. 2019;10:411 pubmed 出版商
Bai F, Yu Z, Gao X, Gong J, Fan L, Liu F. Simvastatin induces breast cancer cell death through oxidative stress up-regulating miR-140-5p. Aging (Albany NY). 2019;11:3198-3219 pubmed 出版商
Wojtak K, Perales Puchalt A, Weiner D. Novel Synthetic DNA Immunogens Targeting Latent Expressed Antigens of Epstein-Barr Virus Elicit Potent Cellular Responses and Inhibit Tumor Growth. Vaccines (Basel). 2019;7: pubmed 出版商
Li J, Xiao Q, Bao Y, Wang W, Goh J, Wang P, et al. HER2-L755S mutation induces hyperactive MAPK and PI3K-mTOR signaling, leading to resistance to HER2 tyrosine kinase inhibitor treatment. Cell Cycle. 2019;18:1513-1522 pubmed 出版商
Bullock B, Kimball A, Poczobutt J, Neuwelt A, Li H, Johnson A, et al. Tumor-intrinsic response to IFNγ shapes the tumor microenvironment and anti-PD-1 response in NSCLC. Life Sci Alliance. 2019;2: pubmed 出版商
Shi F, Zhou M, Shang L, Du Q, Li Y, Xie L, et al. EBV(LMP1)-induced metabolic reprogramming inhibits necroptosis through the hypermethylation of the RIP3 promoter. Theranostics. 2019;9:2424-2438 pubmed 出版商
Carrino M, Quotti Tubi L, Fregnani A, Canovas Nunes S, Barilà G, Trentin L, et al. Prosurvival autophagy is regulated by protein kinase CK1 alpha in multiple myeloma. Cell Death Discov. 2019;5:98 pubmed 出版商
Rutkovsky A, Yeh E, Guest S, Findlay V, Muise Helmericks R, Armeson K, et al. Eukaryotic initiation factor 4E-binding protein as an oncogene in breast cancer. BMC Cancer. 2019;19:491 pubmed 出版商
Lizhnyak P, Muldoon P, Pilaka P, POVLISHOCK J, Ottens A. Traumatic Brain Injury Temporal Proteome Guides KCC2-targeted Therapy. J Neurotrauma. 2019;: pubmed 出版商
Demirev A, Song H, Cho M, Cho K, Peak J, Yoo H, et al. V232M substitution restricts a distinct O-glycosylation of PLD3 and its neuroprotective function. Neurobiol Dis. 2019;: pubmed 出版商
Al Juboori S, Vadakekolathu J, Idri S, Wagner S, Zafeiris D, Pearson J, et al. PYK2 promotes HER2-positive breast cancer invasion. J Exp Clin Cancer Res. 2019;38:210 pubmed 出版商
Pedini F, De Luca G, Felicetti F, Puglisi R, Boe A, Arasi M, et al. Joint action of miR-126 and MAPK/PI3K inhibitors against metastatic melanoma. Mol Oncol. 2019;13:1836-1854 pubmed 出版商
Gladilin E, Ohse S, Boerries M, Busch H, Xu C, Schneider M, et al. TGFβ-induced cytoskeletal remodeling mediates elevation of cell stiffness and invasiveness in NSCLC. Sci Rep. 2019;9:7667 pubmed 出版商
Lee L, Seager R, Nakamura Y, Wilkinson K, Henley J. Parkin-mediated ubiquitination contributes to the constitutive turnover of mitochondrial fission factor (Mff). PLoS ONE. 2019;14:e0213116 pubmed 出版商
Hu Y, Zhang M, Tian N, Li D, Wu F, Hu P, et al. The antibiotic clofoctol suppresses glioma stem cell proliferation by activating KLF13. J Clin Invest. 2019;130: pubmed 出版商
Lindsey R, Xing W, Pourteymoor S, Godwin C, Gow A, Mohan S. Novel Role for Claudin-11 in the Regulation of Osteoblasts via Modulation of ADAM10-Mediated Notch Signaling. J Bone Miner Res. 2019;34:1910-1922 pubmed 出版商
Jiang L, Zhu B, Zhao Y, Li X, Liu T, Piña Crespo J, et al. Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment. J Clin Invest. 2019;130: pubmed 出版商
Wang X, Dong Y, Zhang Y, Li T, Xie Z. Sevoflurane induces cognitive impairment in young mice via autophagy. PLoS ONE. 2019;14:e0216372 pubmed 出版商
Yang Z, Li H, Tang Y, Liu X, Liao Q, Fan C, et al. CYP1B1 deiciency ameliorates learning and memory deficits caused by high fat diet in mice. Am J Transl Res. 2019;11:2194-2206 pubmed
Fouquerel E, Barnes R, Uttam S, Watkins S, Bruchez M, Opresko P. Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis. Mol Cell. 2019;: pubmed 出版商
Campillo Marcos I, Lazo P. Olaparib and ionizing radiation trigger a cooperative DNA-damage repair response that is impaired by depletion of the VRK1 chromatin kinase. J Exp Clin Cancer Res. 2019;38:203 pubmed 出版商
Zurawek D, Gruca P, Antkiewicz Michaluk L, Dziedzicka Wasylewska M. Resilient Phenotype in Chronic Mild Stress Paradigm Is Associated with Altered Expression Levels of miR-18a-5p and Serotonin 5-HT1a Receptor in Dorsal Part of the Hippocampus. Mol Neurobiol. 2019;: pubmed 出版商
Sul O, Rajasekaran M, Park H, Suh J, Choi H. MicroRNA-29b Enhances Osteoclast Survival by Targeting BCL-2-Modifying Factor after Lipopolysaccharide Stimulation. Oxid Med Cell Longev. 2019;2019:6018180 pubmed 出版商
Kuroda T, Yasuda S, Tachi S, Matsuyama S, Kusakawa S, Tano K, et al. SALL3 expression balance underlies lineage biases in human induced pluripotent stem cell differentiation. Nat Commun. 2019;10:2175 pubmed 出版商
Cefis M, Prigent Tessier A, Quirié A, Pernet N, Marie C, Garnier P. The effect of exercise on memory and BDNF signaling is dependent on intensity. Brain Struct Funct. 2019;224:1975-1985 pubmed 出版商
Dougherty U, Mustafi R, Haider H, Khalil A, Souris J, Joseph L, et al. Losartan and Vitamin D Inhibit Colonic Tumor Development in a Conditional Apc-Deleted Mouse Model of Sporadic Colon Cancer. Cancer Prev Res (Phila). 2019;: pubmed 出版商
Yin W, Yang L, Kong D, Nie Y, Liang Y, Teng C. Guanine-rich RNA binding protein GRSF1 inhibits myoblast differentiation through repressing mitochondrial ROS production. Exp Cell Res. 2019;: pubmed 出版商
Lee H, Gallego Villar L, Grisch Chan H, Haeberle J, Thony B, Kruger W. Treatment of CBS deficiency in mice using a minicircle-based naked DNA vector. Hum Gene Ther. 2019;: pubmed 出版商
Speigel I, Ma C, Bichler E, Gooch J, Garcia P. Chronic Calcineurin Inhibition via Cyclosporine A Impairs Visuospatial Learning After Isoflurane Anesthesia. Anesth Analg. 2019;129:192-203 pubmed 出版商
Yin S, Qiu Y, Jin C, Wang R, Wu S, Liu H, et al. 7-Deoxynarciclasine shows promising antitumor efficacy by targeting Akt against hepatocellular carcinoma. Int J Cancer. 2019;145:3334-3346 pubmed 出版商
Kawauchi T, Nabeshima Y. Growth Arrest Triggers Extra-Cell Cycle Regulatory Function in Neurons: Possible Involvement of p27kip1 in Membrane Trafficking as Well as Cytoskeletal Regulation. Front Cell Dev Biol. 2019;7:64 pubmed 出版商
Moreno Jiménez E, Jurado Arjona J, Avila J, Llorens Martín M. The Social Component of Environmental Enrichment Is a Pro-neurogenic Stimulus in Adult c57BL6 Female Mice. Front Cell Dev Biol. 2019;7:62 pubmed 出版商
Duijkers F, McDonald A, Janssens G, Lezzerini M, Jongejan A, van Koningsbruggen S, et al. HNRNPR Variants that Impair Homeobox Gene Expression Drive Developmental Disorders in Humans. Am J Hum Genet. 2019;104:1040-1059 pubmed 出版商
Park C, Park J, Shim M, Rhyu M, Yoon B, Kim K, et al. Indazole-Cl inhibits hypoxia-induced cyclooxygenase-2 expression in vascular smooth muscle cells. J Mol Endocrinol. 2019;63:27-38 pubmed 出版商
Pfannkuch L, Hurwitz R, Traulsen J, Sigulla J, Poeschke M, Matzner L, et al. ADP heptose, a novel pathogen-associated molecular pattern identified in Helicobacter pylori. FASEB J. 2019;:fj201802555R pubmed 出版商
Sobrino P, Ojeda M, Nogales F, Murillo M, Carreras O. Binge drinking affects kidney function, osmotic balance, aldosterone levels, and arterial pressure in adolescent rats: the potential hypotensive effect of selenium mediated by improvements in oxidative balance. Hypertens Res. 2019;: pubmed 出版商
Edwards L, Watt J, Webster T, Schlezinger J. Assessment of total, ligand-induced peroxisome proliferator activated receptor γ ligand activity in serum. Environ Health. 2019;18:45 pubmed 出版商
Jo Y, Sung J, Jeong H, Hong S, Jeong Y, Kim E, et al. Effectiveness of a Fractionated Therapy Scheme in Tumor Treating Fields Therapy. Technol Cancer Res Treat. 2019;18:1533033819845008 pubmed 出版商
Chollat C, Lecointre M, Leuillier M, Remy Jouet I, do Rego J, Abily Donval L, et al. Beneficial Effects of Remifentanil Against Excitotoxic Brain Damage in Newborn Mice. Front Neurol. 2019;10:407 pubmed 出版商
Di Pardo A, Pepe G, Castaldo S, Marracino F, Capocci L, Amico E, et al. Stimulation of Sphingosine Kinase 1 (SPHK1) Is Beneficial in a Huntington's Disease Pre-clinical Model. Front Mol Neurosci. 2019;12:100 pubmed 出版商
Khristunova Y, Korotkova E, Kratochvíl B, Barek J, Dorozhko E, Vyskocil V, et al. Preparation and Investigation of Silver Nanoparticle⁻Antibody Bioconjugates for Electrochemical Immunoassay of Tick-Borne Encephalitis. Sensors (Basel). 2019;19: pubmed 出版商
Himmelreich N, Dimitrov B, Geiger V, Zielonka M, Hutter A, Beedgen L, et al. Novel variants and clinical symptoms in four new ALG3-CDG patients, review of the literature, and identification of AAGRP-ALG3 as a novel ALG3 variant with alanine and glycine-rich N-terminus. Hum Mutat. 2019;: pubmed 出版商
Wu C, Ko J, Pan H, Chiu L, Kang Y, Hsiao Y. Ni-induced TGF-β signaling promotes VEGF-a secretion via integrin β3 upregulation. J Cell Physiol. 2019;234:22093-22102 pubmed 出版商
Nguyen E, Pereira B, Lawrence M, Ma X, Rebello R, Chan H, et al. Proteomic profiling of human prostate cancer-associated fibroblasts (CAF) reveals LOXL2-dependent regulation of the tumor microenvironment. Mol Cell Proteomics. 2019;: pubmed 出版商
Pavlenko E, Cabron A, Arnold P, Dobert J, Rose John S, Zunke F. Functional Characterization of Colon Cancer-Associated Mutations in ADAM17: Modifications in the Pro-Domain Interfere with Trafficking and Maturation. Int J Mol Sci. 2019;20: pubmed 出版商
Zhou X, Wan X, Fu X, Xie C. Puerarin prevents cadmium-induced hepatic cell damage by suppressing apoptosis and restoring autophagic flux. Biomed Pharmacother. 2019;115:108929 pubmed 出版商
Wen C, Fu L, Huang J, Dai Y, Wang B, Xu G, et al. Curcumin reverses doxorubicin resistance via inhibition the efflux function of ABCB4 in doxorubicin‑resistant breast cancer cells. Mol Med Rep. 2019;19:5162-5168 pubmed 出版商
Chen S, Ding L, Zeng N, Liu H, Zheng S, Xu J, et al. Icariin induces irisin/FNDC5 expression in C2C12 cells via the AMPK pathway. Biomed Pharmacother. 2019;115:108930 pubmed 出版商
Yu Z, Yu Z, Chen Z, Yang L, Ma M, Lu S, et al. Zinc chelator TPEN induces pancreatic cancer cell death through causing oxidative stress and inhibiting cell autophagy. J Cell Physiol. 2019;234:20648-20661 pubmed 出版商
Bouchat J, Gilloteaux J, Suain V, Van Vlaender D, Brion J, Nicaise C. Ultrastructural Analysis of Thalamus Damages in a Mouse Model of Osmotic-Induced Demyelination. Neurotox Res. 2019;36:144-162 pubmed 出版商
Plössl K, Straub K, Schmid V, Strunz F, Wild J, Merkl R, et al. Identification of the retinoschisin-binding site on the retinal Na/K-ATPase. PLoS ONE. 2019;14:e0216320 pubmed 出版商
Alves M, de Diego García L, Conte G, Jimenez Mateos E, D Orsi B, Sanz Rodriguez A, et al. Context-Specific Switch from Anti- to Pro-epileptogenic Function of the P2Y1 Receptor in Experimental Epilepsy. J Neurosci. 2019;39:5377-5392 pubmed 出版商
Kim M, Kim I, Sung H, Nam M, Kim Y, Kyung D, et al. Metabolic dysfunction following weight regain compared to initial weight gain in a high-fat diet-induced obese mouse model. J Nutr Biochem. 2019;69:44-52 pubmed 出版商
Follo C, Vidoni C, Morani F, Ferraresi A, Seca C, Isidoro C. Amino acid response by Halofuginone in Cancer cells triggers autophagy through proteasome degradation of mTOR. Cell Commun Signal. 2019;17:39 pubmed 出版商
López Sánchez U, Nicolas G, Richard A, Maltete D, Charif M, Ayrignac X, et al. Characterization of XPR1/SLC53A1 variants located outside of the SPX domain in patients with primary familial brain calcification. Sci Rep. 2019;9:6776 pubmed 出版商
Miorin L, Laurent Rolle M, Pisanelli G, Co P, Albrecht R, Garcia Sastre A, et al. Host-specific NS5 ubiquitination determines yellow fever virus tropism. J Virol. 2019;: pubmed 出版商
Davis M, Delaleau M, Borden K. Nuclear eIF4E Stimulates 3'-End Cleavage of Target RNAs. Cell Rep. 2019;27:1397-1408.e4 pubmed 出版商
Huang X, Wei C, Li F, Jia L, Zeng P, Li J, et al. PCGF6 regulates stem cell pluripotency as a transcription activator via super-enhancer dependent chromatin interactions. Protein Cell. 2019;: pubmed 出版商
Song J, Kang H, Ju H, Park A, Park H, Hong J, et al. Umbilical cord-derived mesenchymal stem cell extracts ameliorate atopic dermatitis in mice by reducing the T cell responses. Sci Rep. 2019;9:6623 pubmed 出版商
Ejaz A, Hatzmann F, Hammerle S, Ritthammer H, Mattesich M, Zwierzina M, et al. Fibroblast feeder layer supports adipogenic differentiation of human adipose stromal/progenitor cells. Adipocyte. 2019;8:178-189 pubmed 出版商
Prieto I, Zambrano A, Laso J, Aranda A, Samper E, Monsalve M. Early induction of senescence and immortalization in PGC-1α-deficient mouse embryonic fibroblasts. Free Radic Biol Med. 2019;138:23-32 pubmed 出版商
Bencheikh L, Diop M, Rivière J, Imanci A, Pierron G, Souquere S, et al. Dynamic gene regulation by nuclear colony-stimulating factor 1 receptor in human monocytes and macrophages. Nat Commun. 2019;10:1935 pubmed 出版商
Wang Z, Feng J, Yu J, Chen G. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. J Cell Sci. 2019;132: pubmed 出版商
Govier Cole A, Wood R, Fletcher J, Gonsalvez D, Merlo D, Cate H, et al. Inhibiting Bone Morphogenetic Protein 4 Type I Receptor Signaling Promotes Remyelination by Potentiating Oligodendrocyte Differentiation. Eneuro. 2019;6: pubmed 出版商
Ni H, Chao X, Kaseff J, Deng F, Wang S, Shi Y, et al. Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3)-Mixed Lineage Kinase Domain-Like Protein (MLKL)-Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers. Am J Pathol. 2019;: pubmed 出版商
Ning J, Zhao C, Chen J, Liao D. Oleate inhibits hepatic autophagy through p38 mitogen-activated protein kinase (MAPK). Biochem Biophys Res Commun. 2019;514:92-97 pubmed 出版商
Uddin M, Akhter M, Siejka A, Catravas J, Barabutis N. P53 supports endothelial barrier function via APE1/Ref1 suppression. Immunobiology. 2019;: pubmed 出版商
Yang Z, Yan H, Dai W, Jing J, Yang Y, Mahajan S, et al. Tmem178 negatively regulates store-operated calcium entry in myeloid cells via association with STIM1. J Autoimmun. 2019;101:94-108 pubmed 出版商
Falcão A, Meijer M, Scaglione A, Rinwa P, Agirre E, Liang J, et al. PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination. Cell Rep. 2019;27:1090-1102.e10 pubmed 出版商
França L, Coêlho C, Freitas L, Souza I, Chagas V, Debbas V, et al. Syzygium cumini Leaf Extract Reverts Hypertriglyceridemia via Downregulation of the Hepatic XBP-1s/PDI/MTP Axis in Monosodium L-Glutamate-Induced Obese Rats. Oxid Med Cell Longev. 2019;2019:9417498 pubmed 出版商
Cheng P, Lin H, Chen Y, Cheng R, Su H, Huang R. The Na+/H+-Exchanger NHE1 Regulates Extra- and Intracellular pH and Nimodipine-sensitive [Ca2+]i in the Suprachiasmatic Nucleus. Sci Rep. 2019;9:6430 pubmed 出版商
Rodriguez Agudo D, Malacrida L, Kakiyama G, Sparrer T, Fortes C, Maceyka M, et al. StarD5: an ER stress protein regulates plasma membrane and intracellular cholesterol homeostasis. J Lipid Res. 2019;60:1087-1098 pubmed 出版商
Nyman M, Jokilammi A, Boström P, Kurki S, Sainio A, Grénman S, et al. Decorin Expression in Human Vulva Carcinoma: Oncosuppressive Effect of Decorin cDNA Transduction on Carcinoma Cells. J Histochem Cytochem. 2019;67:511-522 pubmed 出版商
Kang F, Wang S, So E, Chang M, Wong K, Cheng K, et al. Propofol may increase caspase and MAPK pathways, and suppress the Akt pathway to induce apoptosis in MA‑10 mouse Leydig tumor cells. Oncol Rep. 2019;41:3565-3574 pubmed 出版商
Tottone L, Zhdanovskaya N, Carmona Pestaña Á, Zampieri M, Simeoni F, Lazzari S, et al. Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALL. Front Oncol. 2019;9:198 pubmed 出版商
Ode Y, Aziz M, Jin H, Arif A, Nicastro J, Wang P. Cold-inducible RNA-binding Protein Induces Neutrophil Extracellular Traps in the Lungs during Sepsis. Sci Rep. 2019;9:6252 pubmed 出版商
Liu C, Jiang W, Tian X, Yang P, Xiao L, Li J, et al. Identification of Vigilin as a Potential Ischemia Biomarker by Brain Slice-Based Systematic Evolution of Ligands by Exponential Enrichment. Anal Chem. 2019;91:6675-6681 pubmed 出版商
Xu L, Li Y, Zhou L, Dorfman R, Liu L, Cai R, et al. SIRT3 elicited an anti-Warburg effect through HIF1α/PDK1/PDHA1 to inhibit cholangiocarcinoma tumorigenesis. Cancer Med. 2019;8:2380-2391 pubmed 出版商
Cooke M, Casado Medrano V, Ann J, Lee J, Blumberg P, Abba M, et al. Differential Regulation of Gene Expression in Lung Cancer Cells by Diacyglycerol-Lactones and a Phorbol Ester Via Selective Activation of Protein Kinase C Isozymes. Sci Rep. 2019;9:6041 pubmed 出版商
Zheng J, Croteau D, Bohr V, Akbari M. Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells. Nucleic Acids Res. 2019;: pubmed 出版商
Lin Y, Sun H, Chiu W, Su H, Chien Y, Chang H, et al. Etifoxine, a TSPO Ligand, Worsens Hepatitis C-Related Insulin Resistance but Relieves Lipid Accumulation. Biomed Res Int. 2019;2019:3102414 pubmed 出版商
Chu C, Lee C, Lee J, Wang Y, Huang C, Lan S, et al. MiR-338-5p promotes metastasis of colorectal cancer by inhibition of phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated autophagy pathway. EBioMedicine. 2019;43:270-281 pubmed 出版商
Amor D, Stephenson S, Mustapha M, Mensah M, Ockeloen C, Lee W, et al. Pathogenic Variants in GPC4 Cause Keipert Syndrome. Am J Hum Genet. 2019;104:914-924 pubmed 出版商
Cheng W, Liao T, Lin C, Yuan L, Lan H, Lin H, et al. RAB27B-activated secretion of stem-like tumor exosomes delivers the biomarker microRNA-146a-5p, which promotes tumorigenesis and associates with an immunosuppressive tumor microenvironment in colorectal cancer. Int J Cancer. 2019;: pubmed 出版商
Moslehi M, Ng D, Bogoyevitch M. Pathogenic E2K mutation of doublecortin X (DCX) alters microtubule stabilisation and actin filament association. Biochem Biophys Res Commun. 2019;513:540-545 pubmed 出版商
Dickinson K, Hammond L, Karner C, Hastie N, Carroll T, Goodyer P. Molecular determinants of WNT9b responsiveness in nephron progenitor cells. PLoS ONE. 2019;14:e0215139 pubmed 出版商
Song H, Park J, Choi K, Lee J, Chen J, Park H, et al. Ginsenoside Rf inhibits cyclooxygenase-2 induction via peroxisome proliferator-activated receptor gamma in A549 cells. J Ginseng Res. 2019;43:319-325 pubmed 出版商
Rogers C, Erkes D, Nardone A, Aplin A, Fernandes Alnemri T, Alnemri E. Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation. Nat Commun. 2019;10:1689 pubmed 出版商
Wu M, Li L, Hamaker M, Small D, Duffield A. FLT3/ITD cooperates with Rac1 to modulate the sensitivity of leukemic cells to chemotherapeutic agents via regulation of DNA repair pathways. Haematologica. 2019;: pubmed 出版商
Garcia Silva S, Benito Martin A, Sánchez Redondo S, Hernández Barranco A, Ximénez Embún P, Nogués L, et al. Use of extracellular vesicles from lymphatic drainage as surrogate markers of melanoma progression and BRAF V600E mutation. J Exp Med. 2019;216:1061-1070 pubmed 出版商
Khristi V, Ratri A, Ghosh S, Pathak D, Borosha S, Dai E, et al. Disruption of ESR1 alters the expression of genes regulating hepatic lipid and carbohydrate metabolism in male rats. Mol Cell Endocrinol. 2019;490:47-56 pubmed 出版商
Liang H, Xie X, Song X, Huang M, Su T, Chang X, et al. Orphan nuclear receptor NR4A1 suppresses hyperhomocysteinemia-induced hepatic steatosis in vitro and in vivo. FEBS Lett. 2019;593:1061-1071 pubmed 出版商
Bhat J, Dubin S, Dananberg A, Quabius E, Fritsch J, Dowds C, et al. Histone Deacetylase Inhibitor Modulates NKG2D Receptor Expression and Memory Phenotype of Human Gamma/Delta T Cells Upon Interaction With Tumor Cells. Front Immunol. 2019;10:569 pubmed 出版商
Fukumoto T, Zhu H, Nacarelli T, Karakashev S, Fatkhutdinov N, Wu S, et al. N6-Methylation of Adenosine of FZD10 mRNA Contributes to PARP Inhibitor Resistance. Cancer Res. 2019;79:2812-2820 pubmed 出版商
Martínez M, Ubeda A, Trillo M. Involvement of the EGF Receptor in MAPK Signaling Activation by a 50 Hz Magnetic Field in Human Neuroblastoma Cells. Cell Physiol Biochem. 2019;52:893-907 pubmed 出版商
Bizzarro V, Belvedere R, Pessolano E, Parente L, Petrella F, Perretti M, et al. Mesoglycan induces keratinocyte activation by triggering syndecan-4 pathway and the formation of the annexin A1/S100A11 complex. J Cell Physiol. 2019;234:20174-20192 pubmed 出版商
Mori M, Mori T, Yamamoto A, Takagi S, Ueda M. Proliferation of poorly differentiated endometrial cancer cells through autocrine activation of FGF receptor and HES1 expression. Hum Cell. 2019;32:367-378 pubmed 出版商
Blankenhaus B, Braza F, Martins R, Bastos Amador P, González García I, Carlos A, et al. Ferritin regulates organismal energy balance and thermogenesis. Mol Metab. 2019;24:64-79 pubmed 出版商
Yennawar M, White R, Jensen F. AMPA Receptor Dysregulation and Therapeutic Interventions in a Mouse Model of CDKL5 Deficiency Disorder. J Neurosci. 2019;39:4814-4828 pubmed 出版商
Chakroborty D, Kurppa K, Paatero I, Ojala V, Koivu M, Tamirat M, et al. An unbiased in vitro screen for activating epidermal growth factor receptor mutations. J Biol Chem. 2019;294:9377-9389 pubmed 出版商
Lundberg M, Mattsson A, Reiser K, Holmgren A, Curbo S. Inhibition of the thioredoxin system by PX-12 (1-methylpropyl 2-imidazolyl disulfide) impedes HIV-1 infection in TZM-bl cells. Sci Rep. 2019;9:5656 pubmed 出版商
Yang P, Jiang Y, Rhea P, Coway T, Chen D, Gagea M, et al. Human Biofield Therapy and the Growth of Mouse Lung Carcinoma. Integr Cancer Ther. 2019;18:1534735419840797 pubmed 出版商
Willms A, Schittek H, Rahn S, Sosna J, Mert U, Adam D, et al. Impact of p53 status on TRAIL-mediated apoptotic and non-apoptotic signaling in cancer cells. PLoS ONE. 2019;14:e0214847 pubmed 出版商
Zhang X, Selvaraju K, Saei A, D Arcy P, Zubarev R, Arnér E, et al. Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug. Biochimie. 2019;162:46-54 pubmed 出版商
Wauters F, Cornelissen T, Imberechts D, Martin S, Koentjoro B, Sue C, et al. LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10. Autophagy. 2019;:1-20 pubmed 出版商
Du Q, Tan Z, Shi F, Tang M, Xie L, Zhao L, et al. PGC1α/CEBPB/CPT1A axis promotes radiation resistance of nasopharyngeal carcinoma through activating fatty acid oxidation. Cancer Sci. 2019;110:2050-2062 pubmed 出版商
Anton E, Fernandes D, Assreuy J, da Silva Santos J. Bradykinin increases BP in endotoxemic rat: functional and biochemical evidence of angiotensin II AT1 /bradykinin B2 receptor heterodimerization. Br J Pharmacol. 2019;176:2608-2626 pubmed 出版商
Yoon K, Lee H, Chung H, Lee J, Choi J, Heo J, et al. Discovery of LDD-1075 as a potent FLT3 inhibitor. Oncol Lett. 2019;17:4735-4741 pubmed 出版商
Zaborowski M, Lee K, Na Y, Sammarco A, Zhang X, Iwanicki M, et al. Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles. Cell Rep. 2019;27:255-268.e6 pubmed 出版商
Harms M, Li Q, Lee S, Zhang C, Kull B, Hallen S, et al. Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes. Cell Rep. 2019;27:213-225.e5 pubmed 出版商
Muraoka H, Hasegawa K, Sakamaki Y, Minakuchi H, Kawaguchi T, Yasuda I, et al. Role of Nampt-Sirt6 Axis in Renal Proximal Tubules in Extracellular Matrix Deposition in Diabetic Nephropathy. Cell Rep. 2019;27:199-212.e5 pubmed 出版商
Chen J, Wang F, Huang S, Liu X, Li Z, Qi A, et al. Jian-Pi-Yi-Shen Decoction Relieves Renal Anemia in 5/6 Nephrectomized Rats: Production of Erythropoietin via Hypoxia Inducible Factor Signaling. Evid Based Complement Alternat Med. 2019;2019:2807926 pubmed 出版商
Celaya A, Sanchez Perez I, Bermúdez Muñoz J, Rodriguez de la Rosa L, Pintado Berninches L, Perona R, et al. Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss. elife. 2019;8: pubmed 出版商
Yoshinaga N, Shindo K, Matsui Y, Takiuchi Y, Fukuda H, Nagata K, et al. A screening for DNA damage response molecules that affect HIV-1 infection. Biochem Biophys Res Commun. 2019;513:93-98 pubmed 出版商
Siddharth S, Muniraj N, Saxena N, Sharma D. Concomitant Inhibition of Cytoprotective Autophagy Augments the Efficacy of Withaferin A in Hepatocellular Carcinoma. Cancers (Basel). 2019;11: pubmed 出版商
Gu H, Shi X, Liu C, Wang C, Sui N, Zhao Y, et al. USP8 maintains embryonic stem cell stemness via deubiquitination of EPG5. Nat Commun. 2019;10:1465 pubmed 出版商
Ye X, Wu H, Sheng L, Liu Y, Ye F, Wang M, et al. Oncogenic potential of truncated RXRα during colitis-associated colorectal tumorigenesis by promoting IL-6-STAT3 signaling. Nat Commun. 2019;10:1463 pubmed 出版商
Matsuo K, Cheng A, Yabuki Y, Takahata I, Miyachi H, Fukunaga K. Inhibition of MPTP-induced α-synuclein oligomerization by fatty acid-binding protein 3 ligand in MPTP-treated mice. Neuropharmacology. 2019;150:164-174 pubmed 出版商
Park O, Ha H, Lee Y, Boo S, Kwon D, Song H, et al. Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex. Mol Cell. 2019;74:494-507.e8 pubmed 出版商
Han S, Korm S, Han Y, Choi S, Kim S, Chung H, et al. GCA links TRAF6-ULK1-dependent autophagy activation in resistant chronic myeloid leukemia. Autophagy. 2019;15:2076-2090 pubmed 出版商
Zarei M, Pujol E, Quesada López T, Villarroya F, Barroso E, Vazquez S, et al. Oral administration of a new HRI activator as a new strategy to improve high-fat-diet-induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21. Br J Pharmacol. 2019;176:2292-2305 pubmed 出版商
Edfawy M, Guedes J, Pereira M, Laranjo M, Carvalho M, Gao X, et al. Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant mice. Nat Commun. 2019;10:1431 pubmed 出版商
Sapmaz A, Berlin I, Bos E, Wijdeven R, Janssen H, Konietzny R, et al. USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7. Nat Commun. 2019;10:1454 pubmed 出版商
Simonetta K, Taygerly J, Boyle K, Basham S, Padovani C, Lou Y, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nat Commun. 2019;10:1402 pubmed 出版商
Tobacyk J, Parajuli N, Shrum S, Crow J, Macmillan Crow L. The first direct activity assay for the mitochondrial protease OMA1. Mitochondrion. 2019;46:1-5 pubmed 出版商
Duraisamy A, Mohammad G, Kowluru R. Mitochondrial fusion and maintenance of mitochondrial homeostasis in diabetic retinopathy. Biochim Biophys Acta Mol Basis Dis. 2019;1865:1617-1626 pubmed 出版商
Ucci M, Di Tomo P, Tritschler F, Cordone V, Lanuti P, Bologna G, et al. Anti-inflammatory Role of Carotenoids in Endothelial Cells Derived from Umbilical Cord of Women Affected by Gestational Diabetes Mellitus. Oxid Med Cell Longev. 2019;2019:8184656 pubmed 出版商
Yao W, Rose J, Wang W, Seth S, Jiang H, Taguchi A, et al. Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer. Nature. 2019;: pubmed 出版商
Vehlow A, Klapproth E, Jin S, Hannen R, Hauswald M, Bartsch J, et al. Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-Akt1 Complex Modulates Glioblastoma Therapy Sensitivity. Cell Rep. 2019;26:3672-3683.e7 pubmed 出版商
Taves M, Mittelstadt P, Presman D, Hager G, Ashwell J. Single-Cell Resolution and Quantitation of Targeted Glucocorticoid Delivery in the Thymus. Cell Rep. 2019;26:3629-3642.e4 pubmed 出版商
Duan Y, Dong Y, Hu H, Wang Q, Guo S, Fu D, et al. IL-33 contributes to disease severity in Psoriasis-like models of mouse. Cytokine. 2019;119:159-167 pubmed 出版商
Pang Y, Yamamoto H, Sakamoto H, Oku M, Mutungi J, Sahani M, et al. Evolution from covalent conjugation to non-covalent interaction in the ubiquitin-like ATG12 system. Nat Struct Mol Biol. 2019;: pubmed 出版商
Miramontes González J, Hightower M, Zhang K, Kurosaki H, Schork A, Biswas N, et al. A new common functional coding variant at the DDC gene change renal enzyme activity and modify renal dopamine function. Sci Rep. 2019;9:5055 pubmed 出版商
Wu C, Zhang X, Chen P, Ruan X, Liu W, Li Y, et al. MicroRNA-129 modulates neuronal migration by targeting Fmr1 in the developing mouse cortex. Cell Death Dis. 2019;10:287 pubmed 出版商
Wu X, Hu F, Zeng J, Han L, Qiu D, Wang H, et al. NMNAT2-mediated NAD+ generation is essential for quality control of aged oocytes. Aging Cell. 2019;18:e12955 pubmed 出版商
Yuan C, Li X, Song H, Fan L, Su S, Dong B. BMP7 coordinates endometrial epithelial cell receptivity for blastocyst implantation through the endoglin pathway in cell lines and a mouse model. Exp Ther Med. 2019;17:2547-2556 pubmed 出版商
Wu Z, Isik M, Moroz N, Steinbaugh M, Zhang P, Blackwell T. Dietary Restriction Extends Lifespan through Metabolic Regulation of Innate Immunity. Cell Metab. 2019;29:1192-1205.e8 pubmed 出版商
Murcia Belmonte V, Coca Y, Vegar C, Negueruela S, de Juan Romero C, Valiño A, et al. A Retino-retinal Projection Guided by Unc5c Emerged in Species with Retinal Waves. Curr Biol. 2019;29:1149-1160.e4 pubmed 出版商
Li X, Liang Z, Du J, Wang Z, Mei S, Li Z, et al. Herbal decoctosome is a novel form of medicine. Sci China Life Sci. 2019;: pubmed 出版商
Wang X, Wang H, Xu B, Jiang D, Huang S, Yu H, et al. Depletion of H3K79 methyltransferase Dot1L promotes cell invasion and cancer stem-like cell property in ovarian cancer. Am J Transl Res. 2019;11:1145-1153 pubmed
Ares G, Buonpane C, Sincavage J, Yuan C, Wood D, Hunter C. Caveolin 1 is Associated with Upregulated Claudin 2 in Necrotizing Enterocolitis. Sci Rep. 2019;9:4982 pubmed 出版商
Lu G, Yi J, Gubas A, Wang Y, Wu Y, Ren Y, et al. Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation. Autophagy. 2019;:1-18 pubmed 出版商
Zembrzuska K, Ostrowski R, Matyja E. Hyperbaric oxygen increases glioma cell sensitivity to antitumor treatment with a novel isothiourea derivative in vitro. Oncol Rep. 2019;41:2703-2716 pubmed 出版商
Curto P, Santa C, Allen P, Manadas B, Simões I, Martinez J. A Pathogen and a Non-pathogen Spotted Fever Group Rickettsia Trigger Differential Proteome Signatures in Macrophages. Front Cell Infect Microbiol. 2019;9:43 pubmed 出版商
Wang S, Ni H, Chao X, Wang H, Bridges B, Kumer S, et al. Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis. Autophagy. 2019;15:1954-1969 pubmed 出版商
Alicka M, Sobierajska P, Kornicka K, Wiglusz R, Marycz K. Lithium ions (Li+) and nanohydroxyapatite (nHAp) doped with Li+ enhance expression of late osteogenic markers in adipose-derived stem cells. Potential theranostic application of nHAp doped with Li+ and co-doped with europium (III) and samarium (III) . Mater Sci Eng C Mater Biol Appl. 2019;99:1257-1273 pubmed 出版商
Koh J, Hancock C, Han D, Holloszy J, Nair K, Dasari S. AMPK and PPARβ positive feedback loop regulates endurance exercise training-mediated GLUT4 expression in skeletal muscle. Am J Physiol Endocrinol Metab. 2019;316:E931-E939 pubmed 出版商
Kessler M, Hoffmann K, Fritsche K, Brinkmann V, Mollenkopf H, Thieck O, et al. Chronic Chlamydia infection in human organoids increases stemness and promotes age-dependent CpG methylation. Nat Commun. 2019;10:1194 pubmed 出版商
McNeill R, Mason A, Hodson M, Catto J, Southgate J. Specificity of the Metallothionein-1 Response by Cadmium-Exposed Normal Human Urothelial Cells. Int J Mol Sci. 2019;20: pubmed 出版商
Martín Segura A, Ahmed T, Casadomé Perales Á, Palomares Perez I, Palomer E, Kerstens A, et al. Age-associated cholesterol reduction triggers brain insulin resistance by facilitating ligand-independent receptor activation and pathway desensitization. Aging Cell. 2019;18:e12932 pubmed 出版商
Bhagwani A, Hultman S, Farkas D, Moncayo R, Dandamudi K, Zadu A, et al. Endothelial cells are a source of Nestin expression in Pulmonary Arterial Hypertension. PLoS ONE. 2019;14:e0213890 pubmed 出版商
Inagaki Y, Tokunaga T, Yanai M, Wu D, Huang J, Nagase H, et al. Silencing of EPHB2 promotes the epithelial-mesenchymal transition of skin squamous cell carcinoma-derived A431 cells. Oncol Lett. 2019;17:3735-3742 pubmed 出版商
Karpova Y, Wu C, Divan A, McDonnell M, Hewlett E, Makhov P, et al. Non-NAD-like PARP-1 inhibitors in prostate cancer treatment. Biochem Pharmacol. 2019;: pubmed 出版商
Mahajan S, Decker C, Yang Z, Veis D, Mellins E, Faccio R. Plcγ2/Tmem178 dependent pathway in myeloid cells modulates the pathogenesis of cytokine storm syndrome. J Autoimmun. 2019;100:62-74 pubmed 出版商
Le Guillou S, Laubier J, Pechoux C, Aujean E, Castille J, Leroux C, et al. Defects of the endoplasmic reticulum and changes to lipid droplet size in mammary epithelial cells due to miR-30b-5p overexpression are correlated to a reduction in Atlastin 2 expression. Biochem Biophys Res Commun. 2019;512:283-288 pubmed 出版商
Andersson C, Falsig J, STAVENHAGEN J, Christensen S, Kartberg F, Rosenqvist N, et al. Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes. Sci Rep. 2019;9:4658 pubmed 出版商
Gordon E, Yao X, Xu H, Karkowsky W, Kaler M, Kalchiem Dekel O, et al. Apolipoprotein E is a concentration-dependent pulmonary danger signal that activates the NLRP3 inflammasome and IL-1β secretion by bronchoalveolar fluid macrophages from asthmatic subjects. J Allergy Clin Immunol. 2019;: pubmed 出版商
Sheu S, Chen J, Bee Y, Lin S, Shu C. ERBB2-modulated ATG4B and autophagic cell death in human ARPE19 during oxidative stress. PLoS ONE. 2019;14:e0213932 pubmed 出版商
Jiang Q, Kaili D, Freeman J, Lei C, Geng B, Tan T, et al. Diabetes inhibits corneal epithelial cell migration and tight junction formation in mice and human via increasing ROS and impairing Akt signaling. Acta Pharmacol Sin. 2019;: pubmed 出版商
Simons M, Gorbunova E, Mackow E. Unique Interferon Pathway Regulation by the Andes Virus Nucleocapsid Protein Is Conferred by Phosphorylation of Serine 386. J Virol. 2019;93: pubmed 出版商
Cairó M, Campderros L, Gavaldà Navarro A, Cereijo R, Delgado Anglés A, Quesada López T, et al. Parkin controls brown adipose tissue plasticity in response to adaptive thermogenesis. EMBO Rep. 2019;20: pubmed 出版商
Yücel S, Stelzer W, Lorenzoni A, Wozny M, Langosch D, Lemberg M. The Metastable XBP1u Transmembrane Domain Defines Determinants for Intramembrane Proteolysis by Signal Peptide Peptidase. Cell Rep. 2019;26:3087-3099.e11 pubmed 出版商
Storti F, Klee K, Todorova V, Steiner R, Othman A, van der Velde Visser S, et al. Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration. elife. 2019;8: pubmed 出版商
Huang J, Wang X, Zhu Y, Li Z, Zhu Y, Wu J, et al. Exercise activates lysosomal function in the brain through AMPK-SIRT1-TFEB pathway. CNS Neurosci Ther. 2019;25:796-807 pubmed 出版商
Perruchot M, Gondret F, Robert F, Dupuis E, Quesnel H, Dessauge F. Effect of the flavonoid baicalin on the proliferative capacity of bovine mammary cells and their ability to regulate oxidative stress. Peerj. 2019;7:e6565 pubmed 出版商
Van den Bossche J, Deben C, De Pauw I, Lambrechts H, Hermans C, Deschoolmeester V, et al. In vitro study of the Polo-like kinase 1 inhibitor volasertib in non-small-cell lung cancer reveals a role for the tumor suppressor p53. Mol Oncol. 2019;13:1196-1213 pubmed 出版商
Liu J, Liu Y, Shao J, Li Y, Qin L, Shen H, et al. Zeb1 is important for proper cleavage plane orientation of dividing progenitors and neuronal migration in the mouse neocortex. Cell Death Differ. 2019;: pubmed 出版商
Su L, Zhou L, Chen F, Wang H, Qian H, Sheng Y, et al. Cideb controls sterol-regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites. EMBO J. 2019;38: pubmed 出版商
Eykelenboom J, Gierlinski M, Yue Z, Hegarat N, Pollard H, Fukagawa T, et al. Live imaging of marked chromosome regions reveals their dynamic resolution and compaction in mitosis. J Cell Biol. 2019;218:1531-1552 pubmed 出版商
Song T, Wu H, Li R, Xu H, Rao X, Gao L, et al. Repeated fluoxetine treatment induces long-lasting neurotrophic changes in the medial prefrontal cortex of adult rats. Behav Brain Res. 2019;365:114-124 pubmed 出版商
Coleman D, Gao L, Schwartzman J, Korkola J, Sampson D, Derrick D, et al. Maintenance of MYC expression promotes de novo resistance to BET bromodomain inhibition in castration-resistant prostate cancer. Sci Rep. 2019;9:3823 pubmed 出版商
Cao J, Yang T, Tang D, Zhou F, Qian Y, Zou X. Increased expression of GEF-H1 promotes colon cancer progression by RhoA signaling. Pathol Res Pract. 2019;215:1012-1019 pubmed 出版商
Tai Y, Gallo N, Wang M, Yu J, Van Aelst L. Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron. 2019;102:358-372.e9 pubmed 出版商
Yang W, Tao Y, Wu Y, Zhao X, Ye W, Zhao D, et al. Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair. Nat Commun. 2019;10:1076 pubmed 出版商
Vershkov D, Fainstein N, Suissa S, Golan Lev T, Ben Hur T, Benvenisty N. FMR1 Reactivating Treatments in Fragile X iPSC-Derived Neural Progenitors In Vitro and In Vivo. Cell Rep. 2019;26:2531-2539.e4 pubmed 出版商
Tang H, Shu C, Chen H, Zhang X, Zang Z, Deng C. Constitutively active BRS3 is a genuinely orphan GPCR in placental mammals. PLoS Biol. 2019;17:e3000175 pubmed 出版商
Song C, Zhang J, Qi S, Liu Z, Zhang X, Zheng Y, et al. Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson's diseases. Aging Cell. 2019;18:e12941 pubmed 出版商
Buck T, Hack C, Berg D, Berg U, Kunz L, Mayerhofer A. The NADPH oxidase 4 is a major source of hydrogen peroxide in human granulosa-lutein and granulosa tumor cells. Sci Rep. 2019;9:3585 pubmed 出版商
Rivell A, Petralia R, Wang Y, Clawson E, Moehl K, Mattson M, et al. Sonic hedgehog expression in the postnatal brain. Biol Open. 2019;: pubmed 出版商
Zhang J, Gelman I, Katsuta E, Liang Y, Wang X, Li J, et al. Glucose Drives Growth Factor-Independent Esophageal Cancer Proliferation via Phosphohistidine-Focal Adhesion Kinase Signaling. Cell Mol Gastroenterol Hepatol. 2019;8:37-60 pubmed 出版商
Verma K, Zang T, Penning T, Trippier P. Potent and Highly Selective Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors Act as Chemotherapeutic Potentiators in Acute Myeloid Leukemia and T-Cell Acute Lymphoblastic Leukemia. J Med Chem. 2019;62:3590-3616 pubmed 出版商
Ma B, Cheng H, Mu C, Geng G, Zhao T, Luo Q, et al. The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression. Nat Commun. 2019;10:1034 pubmed 出版商
Gokhale A, Hartwig C, Freeman A, Bassell J, Zlatic S, Sapp Savas C, et al. Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior. J Neurosci. 2019;39:3561-3581 pubmed 出版商
Zhang X, Zhang J, Sun H, Liu X, Zheng Y, Xu D, et al. Defective Phosphatidylglycerol Remodeling Causes Hepatopathy, Linking Mitochondrial Dysfunction to Hepatosteatosis. Cell Mol Gastroenterol Hepatol. 2019;7:763-781 pubmed 出版商
Mashimo M, Bu X, Aoyama K, Kato J, Ishiwata Endo H, Stevens L, et al. PARP1 inhibition alleviates injury in ARH3-deficient mice and human cells. JCI Insight. 2019;4: pubmed 出版商
Yamamoto M, Jin C, Hata T, Yasumizu Y, Zhang Y, Hong D, et al. MUC1-C Integrates Chromatin Remodeling and PARP1 Activity in the DNA Damage Response of Triple-Negative Breast Cancer Cells. Cancer Res. 2019;79:2031-2041 pubmed 出版商
Docherty C, Nilsen M, MacLean M. Influence of 2-Methoxyestradiol and Sex on Hypoxia-Induced Pulmonary Hypertension and Hypoxia-Inducible Factor-1-α. J Am Heart Assoc. 2019;8:e011628 pubmed 出版商
Wang H, Ni H, Chao X, Ma X, Rodriguez Y, Chavan H, et al. Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice. Redox Biol. 2019;22:101148 pubmed 出版商
Duciel L, Anezo O, Mandal K, Laurent C, Planque N, Coquelle F, et al. Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) promotes the aggressiveness of human uveal melanoma through dephosphorylation of CRMP2. Sci Rep. 2019;9:2990 pubmed 出版商
Neuhäuser K, Küper L, Christiansen H, Bogdanova N. Assessment of the role of translationally controlled tumor protein 1 (TPT1/TCTP) in breast cancer susceptibility and ATM signaling. Clin Transl Radiat Oncol. 2019;15:99-107 pubmed 出版商
Elia I, Rossi M, Stegen S, Broekaert D, Doglioni G, Van Gorsel M, et al. Breast cancer cells rely on environmental pyruvate to shape the metastatic niche. Nature. 2019;568:117-121 pubmed 出版商
Yang W, Zhao X, Tao Y, Wu Y, He F, Tang L. Proteomic analysis reveals a protective role of specific macrophage subsets in liver repair. Sci Rep. 2019;9:2953 pubmed 出版商
Han J, Zhang M, Nie C, Jia J, Wang F, Yu J, et al. miR-215 suppresses papillary thyroid cancer proliferation, migration, and invasion through the AKT/GSK-3β/Snail signaling by targeting ARFGEF1. Cell Death Dis. 2019;10:195 pubmed 出版商
Isfort I, Cyra M, Elges S, Kailayangiri S, Altvater B, Rossig C, et al. SS18-SSX-Dependent YAP/TAZ Signaling in Synovial Sarcoma. Clin Cancer Res. 2019;25:3718-3731 pubmed 出版商
Smieszek A, Marycz K, Szustakiewicz K, Kryszak B, Targonska S, Zawisza K, et al. New approach to modification of poly (l-lactic acid) with nano-hydroxyapatite improving functionality of human adipose-derived stromal cells (hASCs) through increased viability and enhanced mitochondrial activity. Mater Sci Eng C Mater Biol Appl. 2019;98:213-226 pubmed 出版商
Tan D, Li Y, Yang C, Li J, Tan S, Chin D, et al. PRMT5 Modulates Splicing for Genome Integrity and Preserves Proteostasis of Hematopoietic Stem Cells. Cell Rep. 2019;26:2316-2328.e6 pubmed 出版商
Shoaito H, Petit J, Chissey A, Auzeil N, Guibourdenche J, Gil S, et al. The Role of Peroxisome Proliferator–Activated Receptor Gamma (PPARγ) in Mono(2-ethylhexyl) Phthalate (MEHP)-Mediated Cytotrophoblast Differentiation. Environ Health Perspect. 2019;127:27003 pubmed 出版商
Forbes L, Andrews M. Grafted Human iPSC-Derived Neural Progenitor Cells Express Integrins and Extend Long-Distance Axons Within the Developing Corticospinal Tract. Front Cell Neurosci. 2019;13:26 pubmed 出版商
Chen D, Lin X, Zhang C, An G, Li Z, Dong B, et al. Activated Wnt signaling promotes growth and progression of AFP-producing gastric cancer in preclinical models. Cancer Manag Res. 2019;11:1349-1362 pubmed 出版商
Nguyen H, Zada S, Lai T, Pham T, Hwang J, AHMED M, et al. Calpain-dependent Beclin1 cleavage stimulates senescence-associated cell death in HT22 hippocampal cells under the oxidative stress conditions. Neurosci Lett. 2019;701:106-111 pubmed 出版商
Huang J, Frid M, Gewitz M, Fallon J, Brown D, Krafsur G, et al. Hypoxia-induced pulmonary hypertension and chronic lung disease: caveolin-1 dysfunction an important underlying feature. Pulm Circ. 2019;9:2045894019837876 pubmed 出版商
Sharma G, Guardia C, Roy A, Vassilev A, Saric A, Griner L, et al. A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis. Autophagy. 2019;15:1694-1718 pubmed 出版商
Ali Y, Dohi K, Okamoto R, Katayama K, Ito M. Novel molecular mechanisms in the inhibition of adrenal aldosterone synthesis: Action of tolvaptan via vasopressin V2 receptor-independent pathway. Br J Pharmacol. 2019;176:1315-1327 pubmed 出版商
Gamayun I, O Keefe S, Pick T, Klein M, Nguyen D, McKibbin C, et al. Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca2+ Leakage from the Endoplasmic Reticulum. Cell Chem Biol. 2019;26:571-583.e6 pubmed 出版商
Yang M, Yen C, Chen Y, Fang C, Li C, Lee K, et al. Somatic mutations of PREX2 gene in patients with hepatocellular carcinoma. Sci Rep. 2019;9:2552 pubmed 出版商
Josa Prado F, Luo J, Rubin P, Henley J, Wilkinson K. Developmental profiles of SUMOylation pathway proteins in rat cerebrum and cerebellum. PLoS ONE. 2019;14:e0212857 pubmed 出版商
Zhang Z, Huang Z, Ong B, Sahu C, Zeng H, Ruan H. Bone marrow adipose tissue-derived stem cell factor mediates metabolic regulation of hematopoiesis. Haematologica. 2019;: pubmed 出版商
Ziesemer S, Möller N, Nitsch A, Muller C, Beule A, Hildebrandt J. Sphingomyelin Depletion from Plasma Membranes of Human Airway Epithelial Cells Completely Abrogates the Deleterious Actions of S. aureus Alpha-Toxin. Toxins (Basel). 2019;11: pubmed 出版商
Wang M, Mao C, Ouyang L, Liu Y, Lai W, Liu N, et al. Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA. Cell Death Differ. 2019;: pubmed 出版商
Trautmann M, Cyra M, Isfort I, Jeiler B, Krüger A, Grünewald I, et al. Phosphatidylinositol-3-kinase (PI3K)/Akt Signaling is Functionally Essential in Myxoid Liposarcoma. Mol Cancer Ther. 2019;18:834-844 pubmed 出版商
Ryu I, Won Y, Ha H, Kim E, Park Y, Kim M, et al. eIF4A3 Phosphorylation by CDKs Affects NMD during the Cell Cycle. Cell Rep. 2019;26:2126-2139.e9 pubmed 出版商
Wang Z, Gong Y, Peng B, Shi R, Fan D, Zhao H, et al. MRE11 UFMylation promotes ATM activation. Nucleic Acids Res. 2019;47:4124-4135 pubmed 出版商
Kim Y, Choi J, Yang M, Hong S, Lee C, Kubota Y, et al. A MST1-FOXO1 cascade establishes endothelial tip cell polarity and facilitates sprouting angiogenesis. Nat Commun. 2019;10:838 pubmed 出版商
Caro Vegas C, Bailey A, Bigi R, Damania B, Dittmer D. Targeting mTOR with MLN0128 Overcomes Rapamycin and Chemoresistant Primary Effusion Lymphoma. MBio. 2019;10: pubmed 出版商
Nacarelli T, Lau L, Fukumoto T, Zundell J, Fatkhutdinov N, Wu S, et al. NAD+ metabolism governs the proinflammatory senescence-associated secretome. Nat Cell Biol. 2019;21:397-407 pubmed 出版商
Nakamura S, Irie K, Tanaka H, Nishikawa K, Suzuki H, Saitoh Y, et al. Morphologic determinant of tight junctions revealed by claudin-3 structures. Nat Commun. 2019;10:816 pubmed 出版商
Ma H, Li Y, Wang X, Wu H, Qi G, Li R, et al. PBK, targeted by EVI1, promotes metastasis and confers cisplatin resistance through inducing autophagy in high-grade serous ovarian carcinoma. Cell Death Dis. 2019;10:166 pubmed 出版商
Parolia A, Venalainen E, Xue H, Mather R, Lin D, Wu R, et al. The long noncoding RNA HORAS5 mediates castration-resistant prostate cancer survival by activating the androgen receptor transcriptional program. Mol Oncol. 2019;13:1121-1136 pubmed 出版商
Bagnjuk K, Stöckl J, Frohlich T, Arnold G, Behr R, Berg U, et al. Necroptosis in primate luteolysis: a role for ceramide. Cell Death Discov. 2019;5:67 pubmed 出版商
Cheng S, Chen N, Lin P, Su J, Chen B, Kuo H, et al. Anti-Invasion and Antiangiogenic Effects of Stellettin B through Inhibition of the Akt/Girdin Signaling Pathway and VEGF in Glioblastoma Cells. Cancers (Basel). 2019;11: pubmed 出版商
Hayakawa K, Kawasaki M, Hirai T, Yoshida Y, Tsushima H, Fujishiro M, et al. MicroRNA-766-3p Contributes to Anti-Inflammatory Responses through the Indirect Inhibition of NF-κB Signaling. Int J Mol Sci. 2019;20: pubmed 出版商
Al Amily I, Dunér P, Groop L, Salehi A. The functional impact of G protein-coupled receptor 142 (Gpr142) on pancreatic β-cell in rodent. Pflugers Arch. 2019;471:633-645 pubmed 出版商
Key J, Mueller A, Gispert S, Matschke L, Wittig I, Corti O, et al. Ubiquitylome profiling of Parkin-null brain reveals dysregulation of calcium homeostasis factors ATP1A2, Hippocalcin and GNA11, reflected by altered firing of noradrenergic neurons. Neurobiol Dis. 2019;127:114-130 pubmed 出版商
Hisaoka Nakashima K, Tomimura Y, Yoshii T, Ohata K, Takada N, Zhang F, et al. High-mobility group box 1-mediated microglial activation induces anxiodepressive-like behaviors in mice with neuropathic pain. Prog Neuropsychopharmacol Biol Psychiatry. 2019;92:347-362 pubmed 出版商
Zahreddine H, Culjkovic Kraljacic B, Gasiorek J, Duchaine J, Borden K. GLI1-Inducible Glucuronidation Targets a Broad Spectrum of Drugs. ACS Chem Biol. 2019;14:348-355 pubmed 出版商
Lu B, Javidi Parsijani P, Makani V, Mehraein Ghomi F, Sarhan W, Sun D, et al. Delivering SaCas9 mRNA by lentivirus-like bionanoparticles for transient expression and efficient genome editing. Nucleic Acids Res. 2019;47:e44 pubmed 出版商
Wang W, Yang X, Dai J, Lu Y, Zhang J, Keller E. Prostate cancer promotes a vicious cycle of bone metastasis progression through inducing osteocytes to secrete GDF15 that stimulates prostate cancer growth and invasion. Oncogene. 2019;38:4540-4559 pubmed 出版商
Campbell N, Shekar A, Aguilar J, Peng D, Navratna V, Yang D, et al. Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in SLC6A3. Proc Natl Acad Sci U S A. 2019;116:3853-3862 pubmed 出版商
Pan D, Li G, Morris Love J, Qi S, Feng L, Mertens M, et al. Herpes Simplex Virus 1 Lytic Infection Blocks MicroRNA (miRNA) Biogenesis at the Stage of Nuclear Export of Pre-miRNAs. MBio. 2019;10: pubmed 出版商
Visa A, Sallán M, Maiques O, Alza L, Talavera E, López Ortega R, et al. T-Type Cav3.1 Channels Mediate Progression and Chemotherapeutic Resistance in Glioblastoma. Cancer Res. 2019;79:1857-1868 pubmed 出版商
Azimi I, Milevskiy M, Chalmers S, Yapa K, Robitaille M, Henry C, et al. ORAI1 and ORAI3 in Breast Cancer Molecular Subtypes and the Identification of ORAI3 as a Hypoxia Sensitive Gene and a Regulator of Hypoxia Responses. Cancers (Basel). 2019;11: pubmed 出版商
Liu M, Zhang Z, Wang H, Chen X, Jin C. Activation of AMPK by metformin promotes renal cancer cell proliferation under glucose deprivation through its interaction with PKM2. Int J Biol Sci. 2019;15:617-627 pubmed 出版商
Ziska A, Tatzelt J, Dudek J, Paton A, Paton J, Zimmermann R, et al. The signal peptide plus a cluster of positive charges in prion protein dictate chaperone-mediated Sec61 channel gating. Biol Open. 2019;8: pubmed 出版商
Exner T, Romero Brey I, Yifrach E, Rivera Monroy J, Schrul B, Zouboulis C, et al. An alternative membrane topology permits lipid droplet localization of peroxisomal fatty acyl-CoA reductase 1. J Cell Sci. 2019;132: pubmed 出版商
Young D, Wignall Fleming E, Busse D, Pickin M, Hankinson J, Randall E, et al. The switch between acute and persistent paramyxovirus infection caused by single amino acid substitutions in the RNA polymerase P subunit. PLoS Pathog. 2019;15:e1007561 pubmed 出版商
Dowling J, Alsabbagh M, Del Casale C, Liu Z, Zhang J. TRADD regulates perinatal development and adulthood survival in mice lacking RIPK1 and RIPK3. Nat Commun. 2019;10:705 pubmed 出版商
Arige V, Agarwal A, Khan A, Kalyani A, Natarajan B, Gupta V, et al. Regulation of Monoamine Oxidase B Gene Expression: Key Roles for Transcription Factors Sp1, Egr1 and CREB, and microRNAs miR-300 and miR-1224. J Mol Biol. 2019;431:1127-1147 pubmed 出版商
Zada S, Hwang J, AHMED M, Lai T, Pham T, Kim D. Control of the Epithelial-to-Mesenchymal Transition and Cancer Metastasis by Autophagy-Dependent SNAI1 Degradation. Cells. 2019;8: pubmed 出版商
Nunes C, Freitas V, Almeida L, Laranjinha J. Red wine extract preserves tight junctions in intestinal epithelial cells under inflammatory conditions: implications for intestinal inflammation. Food Funct. 2019;10:1364-1374 pubmed 出版商
Yao J, Zhang J, Tai W, Deng S, Li T, Wu W, et al. High-Dose Paraquat Induces Human Bronchial 16HBE Cell Death and Aggravates Acute Lung Intoxication in Mice by Regulating Keap1/p65/Nrf2 Signal Pathway. Inflammation. 2019;42:471-484 pubmed 出版商
Lee C, Jeong S, Jang C, Bae H, Kim Y, Park I, et al. Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation. Science. 2019;363:644-649 pubmed 出版商
Zinger L, Merenbakh Lamin K, Klein A, Elazar A, Journo S, Boldes T, et al. Ligand-binding Domain-activating Mutations of ESR1 Rewire Cellular Metabolism of Breast Cancer Cells. Clin Cancer Res. 2019;25:2900-2914 pubmed 出版商
HUFF L, Kikuchi D, Faidley E, Forrester S, Tsai M, LASSEGUE B, et al. Polymerase-δ-interacting protein 2 activates the RhoGEF epithelial cell transforming sequence 2 in vascular smooth muscle cells. Am J Physiol Cell Physiol. 2019;316:C621-C631 pubmed 出版商
Ren L, Deng B, Saloura V, Park J, Nakamura Y. MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells. Oncol Rep. 2019;41:2540-2548 pubmed 出版商
Katsura Y, Ohara T, Noma K, Ninomiya T, Kashima H, Kato T, et al. A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness. Cancers (Basel). 2019;11: pubmed 出版商
Mwangi S, Li G, Ye L, Liu Y, Reichardt F, Yeligar S, et al. Glial Cell Line-Derived Neurotrophic Factor Enhances Autophagic Flux in Mouse and Rat Hepatocytes and Protects Against Palmitate Lipotoxicity. Hepatology. 2019;69:2455-2470 pubmed 出版商
Zhao M, Zhuo M, Zheng X, Su X, Meric Bernstam F. FGFR1β is a driver isoform of FGFR1 alternative splicing in breast cancer cells. Oncotarget. 2019;10:30-44 pubmed 出版商
Davies A, Kim H, González Cano R, Choi J, Back S, Roh S, et al. Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury. Cell. 2019;176:716-728.e18 pubmed 出版商
Liu T, Jiang L, Tavana O, Gu W. The Deubiquitylase OTUB1 Mediates Ferroptosis via Stabilization of SLC7A11. Cancer Res. 2019;79:1913-1924 pubmed 出版商
Simmen S, Cosin Roger J, Melhem H, Maliachovas N, Maane M, Baebler K, et al. Iron Prevents Hypoxia-Associated Inflammation Through the Regulation of Nuclear Factor-κB in the Intestinal Epithelium. Cell Mol Gastroenterol Hepatol. 2019;7:339-355 pubmed 出版商
Lornage X, Romero N, Grosgogeat C, Malfatti E, Donkervoort S, Marchetti M, et al. ACTN2 mutations cause "Multiple structured Core Disease" (MsCD). Acta Neuropathol. 2019;137:501-519 pubmed 出版商
Wohlfahrt T, Rauber S, Uebe S, Luber M, Soare A, Ekici A, et al. PU.1 controls fibroblast polarization and tissue fibrosis. Nature. 2019;566:344-349 pubmed 出版商
Christoforou E, Pitman J. Intrafollicular growth differentiation factor 9: bone morphogenetic 15 ratio determines litter size in mammals†. Biol Reprod. 2019;100:1333-1343 pubmed 出版商
Bai Y, Chen Y, Chen X, Jiang J, Wang X, Wang L, et al. Trichostatin A activates FOXO1 and induces autophagy in osteosarcoma. Arch Med Sci. 2019;15:204-213 pubmed 出版商
Stempel M, Chan B, Juranic Lisnic V, Krmpotic A, Hartung J, Paludan S, et al. The herpesviral antagonist m152 reveals differential activation of STING-dependent IRF and NF-κB signaling and STING's dual role during MCMV infection. EMBO J. 2019;38: pubmed 出版商
Wang G, Long J, Gao Y, Zhang W, Han F, Xu C, et al. SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis. Nat Cell Biol. 2019;21:214-225 pubmed 出版商
Hou X, Zhu S, Zhang H, Li C, Qiu D, Ge J, et al. Mitofusin1 in oocyte is essential for female fertility. Redox Biol. 2019;21:101110 pubmed 出版商
Egiz M, Usui T, Ishibashi M, Zhang X, Shigeta S, Toyoshima M, et al. La-Related Protein 4 as a Suppressor for Motility of Ovarian Cancer Cells. Tohoku J Exp Med. 2019;247:59-67 pubmed 出版商
Insinna C, Lu Q, Teixeira I, Harned A, Semler E, Stauffer J, et al. Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport. Nat Commun. 2019;10:428 pubmed 出版商
Hwang W, Lan H, Cheng W, Huang S, Yang M. Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer. J Hematol Oncol. 2019;12:10 pubmed 出版商
Nazmi A, Field R, Griffin E, Haugh O, Hennessy E, Cox D, et al. Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression. Glia. 2019;67:1254-1276 pubmed 出版商
Kuenzi B, Remsing Rix L, Kinose F, Kroeger J, Lancet J, Padron E, et al. Off-target based drug repurposing opportunities for tivantinib in acute myeloid leukemia. Sci Rep. 2019;9:606 pubmed 出版商
Goldstein N, Haim Y, Mattar P, Hadadi Bechor S, Maixner N, Kovacs P, et al. Leptin stimulates autophagy/lysosome-related degradation of long-lived proteins in adipocytes. Adipocyte. 2019;8:51-60 pubmed 出版商
Lu S, Guo Y, Liang P, Zhang S, Yin S, Yin Y, et al. Suppression of astrocytic autophagy by αB-crystallin contributes to α-synuclein inclusion formation. Transl Neurodegener. 2019;8:3 pubmed 出版商
Kim S, Yi J, Park M. Irradiated endothelial cells modulate the malignancy of liver cancer cells. Oncol Lett. 2019;17:2187-2196 pubmed 出版商
Li X, Song H, Kong F, Guo Y, Chen Y, Zhang L, et al. Pemetrexed exerts anticancer effects by inducing G0/G1-phase cell cycle arrest and activating the NOXA/Mcl-1 axis in human esophageal squamous cell carcinoma cells. Oncol Lett. 2019;17:1851-1858 pubmed 出版商
Zhao X, Cai A, Peng Z, Liang W, Xi H, Li P, et al. JS-K induces reactive oxygen species-dependent anti-cancer effects by targeting mitochondria respiratory chain complexes in gastric cancer. J Cell Mol Med. 2019;23:2489-2504 pubmed 出版商
Saliba J, Coutaud B, Solovieva V, Lu F, Blank V. Regulation of CXCL1 chemokine and CSF3 cytokine levels in myometrial cells by the MAFF transcription factor. J Cell Mol Med. 2019;23:2517-2525 pubmed 出版商
Zhou Q, Li H, Li Y, Tan M, Fan S, Cao C, et al. Inhibiting neddylation modification alters mitochondrial morphology and reprograms energy metabolism in cancer cells. JCI Insight. 2019;4: pubmed 出版商
Wu Y, Ou C, Chien P, Chang H, Ko J, Wang B. Chidamide-induced ROS accumulation and miR-129-3p-dependent cell cycle arrest in non-small lung cancer cells. Phytomedicine. 2019;56:94-102 pubmed 出版商
Jung Kc K, Himmelreich N, Prestegård K, Shi T, Scherer T, Ying M, et al. Phenylalanine hydroxylase variants interact with the co-chaperone DNAJC12. Hum Mutat. 2019;40:483-494 pubmed 出版商
Leboucher A, Ahmed T, Caron E, Tailleux A, Raison S, Joly Amado A, et al. Brain insulin response and peripheral metabolic changes in a Tau transgenic mouse model. Neurobiol Dis. 2019;125:14-22 pubmed 出版商
Sato F, Otsuka T, Kohsaka A, Le H, Bhawal U, Muragaki Y. Smad3 Suppresses Epithelial Cell Migration and Proliferation Via the Clock Gene Dec1, Which Negatively Regulates the Expression of Clock Genes Dec2 and Per1. Am J Pathol. 2019;: pubmed 出版商
Tagawa R, Kawano Y, Minami A, Nishiumi S, Yano Y, Yoshida M, et al. β-hydroxybutyrate protects hepatocytes against endoplasmic reticulum stress in a sirtuin 1-independent manner. Arch Biochem Biophys. 2019;663:220-227 pubmed 出版商
Chang H, Kim M, Lee H, Lee H, Kim G, Lee Y, et al. p53/BNIP3-dependent mitophagy limits glycolytic shift in radioresistant cancer. Oncogene. 2019;38:3729-3742 pubmed 出版商
Liu B, Salgado O, Singh S, Hippen K, Maynard J, Burlingame A, et al. The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation. Nat Commun. 2019;10:354 pubmed 出版商
Andrew R, Fisher K, Heesom K, Kellett K, Hooper N. Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms. J Neurochem. 2019;149:399-412 pubmed 出版商
Ye Q, Zhang Y, Cao Y, Wang X, Guo Y, Chen J, et al. Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects. Cell Chem Biol. 2019;26:366-377.e12 pubmed 出版商
Lu M, Zhu W, Wang X, Tang J, Zhang K, Yu G, et al. ACOT12-Dependent Alteration of Acetyl-CoA Drives Hepatocellular Carcinoma Metastasis by Epigenetic Induction of Epithelial-Mesenchymal Transition. Cell Metab. 2019;29:886-900.e5 pubmed 出版商
Ayaz O, Banga S, Heinze Milne S, Rose R, Pyle W, Howlett S. Long-term testosterone deficiency modifies myofilament and calcium-handling proteins and promotes diastolic dysfunction in the aging mouse heart. Am J Physiol Heart Circ Physiol. 2019;316:H768-H780 pubmed 出版商
Wang D, Cao Q, Zhu W, Hu Y, Zhang X, Yin S, et al. Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus. Fish Physiol Biochem. 2019;: pubmed 出版商
Flint M, Chatterjee P, Lin D, McMullan L, Shrivastava Ranjan P, Bergeron E, et al. A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus. Nat Commun. 2019;10:285 pubmed 出版商
Martínez Calle N, Pascual M, Ordoñez R, San Jose Eneriz E, Kulis M, Miranda E, et al. Epigenomic profiling of myelofibrosis reveals widespread DNA methylation changes in enhancer elements and ZFP36L1 as a potential tumor suppressor gene epigenetically regulated. Haematologica. 2019;: pubmed 出版商
Yadav A, Kumar V, Bailey D, Jang B. AZD1208, a Pan-Pim Kinase Inhibitor, Has Anti-Growth Effect on 93T449 Human Liposarcoma Cells via Control of the Expression and Phosphorylation of Pim-3, mTOR, 4EBP-1, S6, STAT-3 and AMPK. Int J Mol Sci. 2019;20: pubmed 出版商
Song Y, Lee S, Kim A, Kim S, Heo J, Shum D, et al. Identification of radiation-induced EndMT inhibitors through cell-based phenomic screening. FEBS Open Bio. 2019;9:82-91 pubmed 出版商
Kim D, Vo M, Choi S, Lee J, Jeong S, Hong C, et al. Tristetraprolin-mediated hexokinase 2 expression regulation contributes to glycolysis in cancer cells. Mol Biol Cell. 2019;30:542-553 pubmed 出版商
Li J, Wu X, Lee A, Zhou S, Owyang C. Altered R-spondin 1/CART neurocircuit in the hypothalamus contributes to hyperphagia in diabetes. J Neurophysiol. 2019;121:928-939 pubmed 出版商
Kuo Y, Lin C, Kuo H, Hung J, Liu C, Jassey A, et al. Identification of baicalin from Bofutsushosan and Daisaikoto as a potent inducer of glucose uptake and modulator of insulin signaling-associated pathways. J Food Drug Anal. 2019;27:240-248 pubmed 出版商
Park C, Peng C, Brennan G, Rothenburg S. Species-specific inhibition of antiviral protein kinase R by capripoxviruses and vaccinia virus. Ann N Y Acad Sci. 2019;1438:18-29 pubmed 出版商
An H, Skelt L, Notaro A, Highley J, Fox A, La Bella V, et al. ALS-linked FUS mutations confer loss and gain of function in the nucleus by promoting excessive formation of dysfunctional paraspeckles. Acta Neuropathol Commun. 2019;7:7 pubmed 出版商
Wangtrakuldee P, Adeniji A, Zang T, Duan L, Khatri B, Twenter B, et al. A 3-(4-nitronaphthen-1-yl) amino-benzoate analog as a bifunctional AKR1C3 inhibitor and AR antagonist: Head to head comparison with other advanced AKR1C3 targeted therapeutics. J Steroid Biochem Mol Biol. 2019;: pubmed 出版商
Henriksson J, Chen X, Gomes T, Ullah U, Meyer K, Miragaia R, et al. Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation. Cell. 2019;176:882-896.e18 pubmed 出版商
Zhao W, Zhang S, Wang X, Ma X, Huang B, Chen H, et al. ETS1 targets RYBP transcription to inhibit tumor cell proliferation. Biochem Biophys Res Commun. 2019;: pubmed 出版商
Santana Codina N, Gableske S, Quiles Del Rey M, Małachowska B, Jedrychowski M, Biancur D, et al. NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms. Haematologica. 2019;: pubmed 出版商
Marx S, Van Gysel M, Breuer A, Dal Maso T, Michiels C, Wouters J, et al. Potentialization of anticancer agents by identification of new chemosensitizers active under hypoxia. Biochem Pharmacol. 2019;162:224-236 pubmed 出版商
Koike K, Beatman E, Schweitzer K, Justice M, Mikosz A, Ni K, et al. Subcutaneous administration of neutralizing antibodies to endothelial monocyte-activating protein II attenuates cigarette smoke-induced lung injury in mice. Am J Physiol Lung Cell Mol Physiol. 2019;316:L558-L566 pubmed 出版商
Huang C, Cheng S, Wu C, Li W, Wang J, Kung M, et al. Delta-like 1 homologue promotes tumorigenesis and epithelial-mesenchymal transition of ovarian high-grade serous carcinoma through activation of Notch signaling. Oncogene. 2019;38:3201-3215 pubmed 出版商
Moslehi M, Ng D, Bogoyevitch M. Doublecortin X (DCX) serine 28 phosphorylation is a regulatory switch, modulating association of DCX with microtubules and actin filaments. Biochim Biophys Acta Mol Cell Res. 2019;1866:638-649 pubmed 出版商
Nemec A, Peterson A, Warnock J, Reed R, Tomko R. An Allosteric Interaction Network Promotes Conformation State-Dependent Eviction of the Nas6 Assembly Chaperone from Nascent 26S Proteasomes. Cell Rep. 2019;26:483-495.e5 pubmed 出版商
Brailoiu E, Chakraborty S, Brailoiu G, Zhao P, Barr J, Ilies M, et al. Choline Is an Intracellular Messenger Linking Extracellular Stimuli to IP3-Evoked Ca2+ Signals through Sigma-1 Receptors. Cell Rep. 2019;26:330-337.e4 pubmed 出版商
Ono S, Matsuda J, Watanabe E, Akaike H, Teranishi H, Miyata I, et al. Novel neuroblastoma amplified sequence (NBAS) mutations in a Japanese boy with fever-triggered recurrent acute liver failure. Hum Genome Var. 2019;6:2 pubmed 出版商
Picco M, Castro M, Quezada M, Barbero G, Villanueva M, Fernández N, et al. STAT3 enhances the constitutive activity of AGC kinases in melanoma by transactivating PDK1. Cell Biosci. 2019;9:3 pubmed 出版商
Domenici G, Aurrekoetxea Rodríguez I, Simões B, Rábano M, Lee S, Millán J, et al. A Sox2-Sox9 signalling axis maintains human breast luminal progenitor and breast cancer stem cells. Oncogene. 2019;38:3151-3169 pubmed 出版商
Baechler S, Factor V, Dalla Rosa I, Ravji A, Becker D, Khiati S, et al. The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis. Nat Commun. 2019;10:83 pubmed 出版商
Park B, Chang S, Lee G, Kang B, Kim J, Park H. Wnt3a disrupts GR-TEAD4-PPARγ2 positive circuits and cytoskeletal rearrangement in a β-catenin-dependent manner during early adipogenesis. Cell Death Dis. 2019;10:16 pubmed 出版商
Dai W, Ryu T, Kim H, Jin Y, Cho Y, Kim K. Effects of δ-Catenin on APP by Its Interaction with Presenilin-1. Mol Cells. 2019;42:36-44 pubmed 出版商
Forrester S, Xu Q, Kikuchi D, Okwan Duodu D, Campos A, Faidley E, et al. Poldip2 deficiency protects against lung edema and vascular inflammation in a model of acute respiratory distress syndrome. Clin Sci (Lond). 2019;133:321-334 pubmed 出版商
Park S, Lee S, Lee W, Choi R, Kim S, Woo H, et al. MicroRNA expression profiling of adult hippocampal neural stem cells upon cell death reveals an autophagic cell death-like pattern. Biochem Biophys Res Commun. 2019;509:674-679 pubmed 出版商
Nakatomi C, Nakatomi M, Matsubara T, Komori T, Doi Inoue T, Ishimaru N, et al. Constitutive activation of the alternative NF-κB pathway disturbs endochondral ossification. Bone. 2019;121:29-41 pubmed 出版商
Nayak R, Hegde S, Althoff M, Wellendorf A, Mohmoud F, Perentesis J, et al. The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors. Nat Commun. 2019;10:46 pubmed 出版商
García Carpizo V, Ruiz Llorente S, Sarmentero J, González Corpas A, Barrero M. CREBBP/EP300 Bromodomain Inhibition Affects the Proliferation of AR-Positive Breast Cancer Cell Lines. Mol Cancer Res. 2019;17:720-730 pubmed 出版商
Garcia D, Hellberg K, Chaix A, Wallace M, Herzig S, Badur M, et al. Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD. Cell Rep. 2019;26:192-208.e6 pubmed 出版商
Cardoso H, Vaz C, Carvalho T, Figueira M, Socorro S. Tyrosine kinase inhibitor imatinib modulates the viability and apoptosis of castrate-resistant prostate cancer cells dependently on the glycolytic environment. Life Sci. 2019;218:274-283 pubmed 出版商
Liu Y, Qin S, Chen T, Lei M, Dhar S, Ho J, et al. Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4. Nat Commun. 2019;10:36 pubmed 出版商
Martínez Puente D, Perez Trujillo J, Gutierrez Puente Y, Rodriguez Rocha H, Garcia Garcia A, Saucedo Cardenas O, et al. Targeting HPV-16 antigens to the endoplasmic reticulum induces an endoplasmic reticulum stress response. Cell Stress Chaperones. 2019;24:149-158 pubmed 出版商
Gong Z, Wang X, Wang J, Fan R, Wang L. Trehalose prevents cadmium-induced hepatotoxicity by blocking Nrf2 pathway, restoring autophagy and inhibiting apoptosis. J Inorg Biochem. 2019;192:62-71 pubmed 出版商
Gomez Lopez N, Romero R, Garcia Flores V, Leng Y, Miller D, Hassan S, et al. Inhibition of the NLRP3 inflammasome can prevent sterile intra-amniotic inflammation, preterm labor/birth, and adverse neonatal outcomes†. Biol Reprod. 2019;100:1306-1318 pubmed 出版商
Timilsina U, Ghimire D, Sharma S, Gaur R. Role of APOBEC3 proteins in proteasome inhibitor-mediated reactivation of latent HIV-1 viruses. J Gen Virol. 2019;100:523-532 pubmed 出版商
Wang J, Shibayama Y, Zhang A, Ohsaki H, Asano E, Suzuki Y, et al. (Pro)renin receptor promotes colorectal cancer through the Wnt/beta-catenin signalling pathway despite constitutive pathway component mutations. Br J Cancer. 2019;120:229-237 pubmed 出版商
Joseph C, Arshad M, Kurozomi S, Althobiti M, Miligy I, Al Izzi S, et al. Overexpression of the cancer stem cell marker CD133 confers a poor prognosis in invasive breast cancer. Breast Cancer Res Treat. 2019;174:387-399 pubmed 出版商
Bonsi P, Ponterio G, Vanni V, Tassone A, Sciamanna G, Migliarini S, et al. RGS9-2 rescues dopamine D2 receptor levels and signaling in DYT1 dystonia mouse models. EMBO Mol Med. 2019;11: pubmed 出版商
Piao L, Yuan X, Zhuang M, Qiu X, Xu X, Kong R, et al. Histone methyltransferase SUV39H2 serves oncogenic roles in osteosarcoma. Oncol Rep. 2019;41:325-332 pubmed 出版商
Yu S, Jean Charles P, Abraham D, Kaur S, Gareri C, Mao L, et al. The deubiquitinase ubiquitin-specific protease 20 is a positive modulator of myocardial β1-adrenergic receptor expression and signaling. J Biol Chem. 2019;294:2500-2518 pubmed 出版商
Fudhaili A, Yoon N, Kang S, Ryu J, Jeong J, Lee D, et al. Resveratrol epigenetically regulates the expression of zinc finger protein 36 in non‑small cell lung cancer cell lines. Oncol Rep. 2019;41:1377-1386 pubmed 出版商
Weber R, Meister M, Muley T, Thomas M, Sultmann H, Warth A, et al. Pathways regulating the expression of the immunomodulatory protein glycodelin in non‑small cell lung cancer. Int J Oncol. 2019;54:515-526 pubmed 出版商
Woodley E, Osmon K, Thompson P, Richmond C, Chen Z, Gray S, et al. Efficacy of a Bicistronic Vector for Correction of Sandhoff Disease in a Mouse Model. Mol Ther Methods Clin Dev. 2019;12:47-57 pubmed 出版商
Wang M, Fan R, Li W, Zhang D, Yang D, Wang Z, et al. Activation of PERK-eIF2α-ATF4-CHOP axis triggered by excessive ER stress contributes to lead-induced nephrotoxicity. Biochim Biophys Acta Mol Cell Res. 2019;1866:713-726 pubmed 出版商
Wu R, Dang F, Li P, Wang P, Xu Q, Liu Z, et al. The Circadian Protein Period2 Suppresses mTORC1 Activity via Recruiting Tsc1 to mTORC1 Complex. Cell Metab. 2019;29:653-667.e6 pubmed 出版商
Fanning S, Haque A, Imberdis T, Baru V, Barrasa M, Nuber S, et al. Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment. Mol Cell. 2019;73:1001-1014.e8 pubmed 出版商
Lopes Coelho F, Silva F, Hipólito A, Cardoso B, Serpa J. Acetylation drives hepatocyte nuclear factor 1β stability by blocking proteasome-mediated degradation. J Cell Biochem. 2019;120:9337-9344 pubmed 出版商
Li X, Meng L, Wang F, Hu X, Yu Y. Sodium fluoride induces apoptosis and autophagy via the endoplasmic reticulum stress pathway in MC3T3-E1 osteoblastic cells. Mol Cell Biochem. 2019;454:77-85 pubmed 出版商
Choi H, Kim C, Song H, Cha M, Cho H, Son S, et al. Amyloid β-induced elevation of O-GlcNAcylated c-Fos promotes neuronal cell death. Aging Cell. 2019;18:e12872 pubmed 出版商
Lian X, Wu X, Li Z, Zhang Y, Song K, Cai G, et al. The combination of metformin and 2-deoxyglucose significantly inhibits cyst formation in miniature pigs with polycystic kidney disease. Br J Pharmacol. 2019;176:711-724 pubmed 出版商
Quesada V, Freitas Rodríguez S, Miller J, Pérez Silva J, Jiang Z, Tapia W, et al. Giant tortoise genomes provide insights into longevity and age-related disease. Nat Ecol Evol. 2019;3:87-95 pubmed 出版商
Hiono T, Matsuda A, Wagatsuma T, Okamatsu M, Sakoda Y, Kuno A. Lectin microarray analyses reveal host cell-specific glycan profiles of the hemagglutinins of influenza A viruses. Virology. 2019;527:132-140 pubmed 出版商
Cramer G, Shin M, Hagan S, Katz S, Simone C, Busch T, et al. Modeling Epidermal Growth Factor Inhibitor-mediated Enhancement of Photodynamic Therapy Efficacy Using 3D Mesothelioma Cell Culture. Photochem Photobiol. 2019;95:397-405 pubmed 出版商
Guo Y, Liang P, Lu S, Chen R, Yin Y, Zhou J. Extracellular αB-crystallin modulates the inflammatory responses. Biochem Biophys Res Commun. 2019;508:282-288 pubmed 出版商
Li X, Gao M, He Y, Xiong B, Liu H, Gu L. Intersectin-Cdc42 interaction is required for orderly meiosis in porcine oocytes. J Cell Physiol. 2019;234:7492-7497 pubmed 出版商
Cysique L, Jugé L, Lennon M, Gates T, Jones S, Lovelace M, et al. HIV brain latency as measured by CSF BcL11b relates to disrupted brain cellular energy in virally suppressed HIV infection. AIDS. 2019;33:433-441 pubmed 出版商
Craze M, El Ansari R, Aleskandarany M, Cheng K, Alfarsi L, Masisi B, et al. Glutamate dehydrogenase (GLUD1) expression in breast cancer. Breast Cancer Res Treat. 2019;174:79-91 pubmed 出版商
Zhao H, Martin E, Matalkah F, Shah N, Ivanov A, Ruppert J, et al. Conditional knockout of SHP2 in ErbB2 transgenic mice or inhibition in HER2-amplified breast cancer cell lines blocks oncogene expression and tumorigenesis. Oncogene. 2019;38:2275-2290 pubmed 出版商
Saifetiarova J, Bhat M. Ablation of cytoskeletal scaffolding proteins, Band 4.1B and Whirlin, leads to cerebellar purkinje axon pathology and motor dysfunction. J Neurosci Res. 2019;97:313-331 pubmed 出版商
Yao M, Fang W, Smart C, Hu Q, Huang S, Alvarez N, et al. CCR2 Chemokine Receptors Enhance Growth and Cell-Cycle Progression of Breast Cancer Cells through SRC and PKC Activation. Mol Cancer Res. 2019;17:604-617 pubmed 出版商
Liang S, Ma H, Zhong Z, Dhar D, Liu X, Xu J, et al. NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice. Gastroenterology. 2019;156:1156-1172.e6 pubmed 出版商
Aditi -, Mason A, Sharma M, Dawson T, Wente S. MAPK- and glycogen synthase kinase 3-mediated phosphorylation regulates the DEAD-box protein modulator Gle1 for control of stress granule dynamics. J Biol Chem. 2019;294:559-575 pubmed 出版商
Ma Y, Cui D, Xiong X, Inuzuka H, Wei W, Sun Y, et al. SCFβ-TrCP ubiquitinates CHK1 in an AMPK-dependent manner in response to glucose deprivation. Mol Oncol. 2019;13:307-321 pubmed 出版商
Romeo M, Masuelli L, Gaeta A, Nazzari C, Granato M, Gilardini Montani M, et al. Impact of HHV-6A and HHV-6B lytic infection on autophagy and endoplasmic reticulum stress. J Gen Virol. 2019;100:89-98 pubmed 出版商
Barabutis N, Uddin M, Catravas J. Hsp90 inhibitors suppress P53 phosphorylation in LPS - induced endothelial inflammation. Cytokine. 2019;113:427-432 pubmed 出版商
Eichner L, Brun S, Herzig S, Young N, Curtis S, Shackelford D, et al. Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models. Cell Metab. 2019;29:285-302.e7 pubmed 出版商
Wang G, Wang Q, Huang Q, Chen Y, Sun X, He L, et al. Upregulation of mtSSB by interleukin-6 promotes cell growth through mitochondrial biogenesis-mediated telomerase activation in colorectal cancer. Int J Cancer. 2019;144:2516-2528 pubmed 出版商
Brasell E, Chu L, El Kares R, Seo J, Loesch R, Iglesias D, et al. The aminoglycoside geneticin permits translational readthrough of the CTNS W138X nonsense mutation in fibroblasts from patients with nephropathic cystinosis. Pediatr Nephrol. 2019;34:873-881 pubmed 出版商
Pinho T, Correia S, Perry G, Ambrósio A, Moreira P. Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies. Biochim Biophys Acta Mol Basis Dis. 2019;1865:2048-2059 pubmed 出版商
Matsushita A, Sato T, Mukai S, Fujishita T, Mishiro Sato E, Okuda M, et al. TAZ activation by Hippo pathway dysregulation induces cytokine gene expression and promotes mesothelial cell transformation. Oncogene. 2019;38:1966-1978 pubmed 出版商
Gu L, Xu H, Zhang C, Yang Q, Zhang L, Zhang J. Time-dependent changes in hypoxia- and gliosis-related factors in experimental diabetic retinopathy. Eye (Lond). 2019;33:600-609 pubmed 出版商
Kleemann M, Schneider H, Unger K, Bereuther J, Fischer S, Sander P, et al. Induction of apoptosis in ovarian cancer cells by miR-493-3p directly targeting AKT2, STK38L, HMGA2, ETS1 and E2F5. Cell Mol Life Sci. 2019;76:539-559 pubmed 出版商
Sprenger H, Wani G, Hesseling A, König T, Patron M, MacVicar T, et al. Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med. 2019;11: pubmed 出版商
Akuta K, Kashiwagi H, Yujiri T, Nishiura N, Morikawa Y, Kato H, et al. A unique phenotype of acquired Glanzmann thrombasthenia due to non-function-blocking anti-αIIbβ3 autoantibodies. J Thromb Haemost. 2019;17:206-219 pubmed 出版商
Meliopoulos V, Livingston B, Van De Velde L, Honce R, Schultz Cherry S. Absence of β6 Integrin Reduces Influenza Disease Severity in Highly Susceptible Obese Mice. J Virol. 2019;93: pubmed 出版商
Zhou Z, Lu Y, Wang Y, Du L, Zhang Y, Tao J. Let-7c regulates proliferation and osteodifferentiation of human adipose-derived mesenchymal stem cells under oxidative stress by targeting SCD-1. Am J Physiol Cell Physiol. 2019;316:C57-C69 pubmed 出版商
Gong X, Du J, Parsons S, Merzoug F, Webster Y, Iversen P, et al. Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene. Cancer Discov. 2019;9:248-263 pubmed 出版商
Ye F, Chen S, Liu X, Ye X, Wang K, Zeng Z, et al. 3-Cl-AHPC inhibits pro-HGF maturation by inducing matriptase/HAI-1 complex formation. J Cell Mol Med. 2019;23:155-166 pubmed 出版商
Kornicka K, Szłapka Kosarzewska J, Smieszek A, Marycz K. 5-Azacytydine and resveratrol reverse senescence and ageing of adipose stem cells via modulation of mitochondrial dynamics and autophagy. J Cell Mol Med. 2019;23:237-259 pubmed 出版商
Liu G, Li Y, Du B, Sun Q, Qi W, Liu Y, et al. Primordial follicle activation is affected by the absence of Sohlh1 in mice. Mol Reprod Dev. 2019;86:20-31 pubmed 出版商
Shaik F, Medapati M, Chelikani P. Cholesterol modulates the signaling of chemosensory bitter taste receptor T2R14 in human airway cells. Am J Physiol Lung Cell Mol Physiol. 2019;316:L45-L57 pubmed 出版商
Wang L, Fan R, Yang D, Zhang D, Wang L. Puerarin reverses cadmium-induced lysosomal dysfunction in primary rat proximal tubular cells via inhibiting Nrf2 pathway. Biochem Pharmacol. 2019;162:132-141 pubmed 出版商
Wu M, Lao Y, Tan H, Lu G, Ren Y, Zheng Z, et al. Oblongifolin C suppresses lysosomal function independently of TFEB nuclear translocation. Acta Pharmacol Sin. 2019;40:929-937 pubmed 出版商
Gilardini Montani M, Santarelli R, Granato M, Gonnella R, Torrisi M, Faggioni A, et al. EBV reduces autophagy, intracellular ROS and mitochondria to impair monocyte survival and differentiation. Autophagy. 2019;15:652-667 pubmed 出版商
Tegtmeyer N, Harrer A, Schmitt V, Singer B, Backert S. Expression of CEACAM1 or CEACAM5 in AZ-521 cells restores the type IV secretion deficiency for translocation of CagA by Helicobacter pylori. Cell Microbiol. 2019;21:e12965 pubmed 出版商
Singh R, Holz P, Roth K, Hupfer A, Meissner W, Muller R, et al. DYRK1B regulates Hedgehog-induced microtubule acetylation. Cell Mol Life Sci. 2019;76:193-207 pubmed 出版商
Qin Y, He Y, Zhu Y, Li M, Ni Y, Liu J, et al. CID1067700, a late endosome GTPase Rab7 receptor antagonist, attenuates brain atrophy, improves neurologic deficits and inhibits reactive astrogliosis in rat ischemic stroke. Acta Pharmacol Sin. 2019;40:724-736 pubmed 出版商
Song Y, Kim M, Sun H, Kim H, Shin H, Kim Y, et al. Aberrant Thyroid-Stimulating Hormone Receptor Signaling Increases VEGF-A and CXCL8 Secretion of Thyroid Cancer Cells, Contributing to Angiogenesis and Tumor Growth. Clin Cancer Res. 2019;25:414-425 pubmed 出版商
Ladli M, Richard C, Aguilar L, Ducamp S, Bondu S, Sujobert P, et al. Finely-tuned regulation of AMP-activated protein kinase is crucial for human adult erythropoiesis. Haematologica. 2019;104:907-918 pubmed 出版商
Lo S, Macmillan Crow L, Parajuli N. Renal cold storage followed by transplantation impairs proteasome function and mitochondrial protein homeostasis. Am J Physiol Renal Physiol. 2019;316:F42-F53 pubmed 出版商
Gorgulu K, Diakopoulos K, Ai J, Schoeps B, Kabacaoglu D, Karpathaki A, et al. Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice. Gastroenterology. 2019;156:203-217.e20 pubmed 出版商
Tantravedi S, Vesuna F, Winnard P, Martin A, Lim M, Eberhart C, et al. Targeting DDX3 in Medulloblastoma Using the Small Molecule Inhibitor RK-33. Transl Oncol. 2019;12:96-105 pubmed 出版商
Williams H, Ma J, Weiss D, LASSEGUE B, Sutliff R, San Martin A. The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo. Lab Invest. 2019;99:399-410 pubmed 出版商
Axelrod H, Valkenburg K, Amend S, Hicks J, Parsana P, Torga G, et al. AXL Is a Putative Tumor Suppressor and Dormancy Regulator in Prostate Cancer. Mol Cancer Res. 2019;17:356-369 pubmed 出版商
Moon J, Jeong J, Hong J, Seol J, Park S. Inhibition of Autophagy by Captopril Attenuates Prion Peptide-Mediated Neuronal Apoptosis via AMPK Activation. Mol Neurobiol. 2019;56:4192-4202 pubmed 出版商
Gentric G, Kieffer Y, Mieulet V, Goundiam O, Bonneau C, Nemati F, et al. PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers. Cell Metab. 2019;29:156-173.e10 pubmed 出版商
Prasad H, Dang D, Kondapalli K, Natarajan N, Cebotaru V, Rao R. NHA2 promotes cyst development in an in vitro model of polycystic kidney disease. J Physiol. 2019;597:499-519 pubmed 出版商
Arbel Rubinstein T, Shahmoon S, Zigmond E, Etan T, Merenbakh Lamin K, Pasmanik Chor M, et al. Klotho suppresses colorectal cancer through modulation of the unfolded protein response. Oncogene. 2019;38:794-807 pubmed 出版商
Ha Thi H, Kim H, Lee Y, Kim S, Hong S. SMAD7 in keratinocytes promotes skin carcinogenesis by activating ATM-dependent DNA repair and an EGFR-mediated cell proliferation pathway. Carcinogenesis. 2019;40:112-120 pubmed 出版商
Lopes Ventura S, Pojo M, Matias A, Moura M, Marques I, Leite V, et al. The efficacy of HRAS and CDK4/6 inhibitors in anaplastic thyroid cancer cell lines. J Endocrinol Invest. 2019;42:527-540 pubmed 出版商
Traboulsi T, El Ezzy M, Dumeaux V, Audemard E, Mader S. Role of SUMOylation in differential ERα transcriptional repression by tamoxifen and fulvestrant in breast cancer cells. Oncogene. 2019;38:1019-1037 pubmed 出版商
Vinue A, Martinez Hervas S, Herrero Cervera A, SÁnchez GarcÍa V, Andrés Blasco I, Piqueras L, et al. Changes in CDKN2A/2B expression associate with T-cell phenotype modulation in atherosclerosis and type 2 diabetes mellitus. Transl Res. 2019;203:31-48 pubmed 出版商
Negoita F, Blomdahl J, Wasserstrom S, Winberg M, Osmark P, Larsson S, et al. PNPLA3 variant M148 causes resistance to starvation-mediated lipid droplet autophagy in human hepatocytes. J Cell Biochem. 2019;120:343-356 pubmed 出版商
Li H, Ham A, Ma T, Kuo S, Kanter E, Kim D, et al. Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations. Autophagy. 2019;15:113-130 pubmed 出版商
Pedard M, Cefis M, Ennequin G, Quirié A, Garnier P, Prigent Tessier A, et al. Brain-derived Neurotrophic Factor Pathway after Downhill and Uphill Training in Rats. Med Sci Sports Exerc. 2019;51:27-34 pubmed 出版商
Jin H, Aziz M, Ode Y, Wang P. CIRP Induces Neutrophil Reverse Transendothelial Migration in Sepsis. Shock. 2019;51:548-556 pubmed 出版商
Zhang L, Qiang P, Yu J, Miao Y, Chen Z, Qu J, et al. Identification of compound CA-5f as a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer. Autophagy. 2019;15:391-406 pubmed 出版商
Ezquerro S, Mocha F, Fruhbeck G, Guzmán Ruiz R, Valenti V, Mugueta C, et al. Ghrelin Reduces TNF-α-Induced Human Hepatocyte Apoptosis, Autophagy, and Pyroptosis: Role in Obesity-Associated NAFLD. J Clin Endocrinol Metab. 2019;104:21-37 pubmed 出版商
Aubert P, Oleynikova E, Rizvi H, Ndjim M, Le Berre Scoul C, Grohard P, et al. Maternal protein restriction induces gastrointestinal dysfunction and enteric nervous system remodeling in rat offspring. FASEB J. 2019;33:770-781 pubmed 出版商
Frisan T, Nagy N, Chioureas D, Terol M, Grasso F, Masucci M. A bacterial genotoxin causes virus reactivation and genomic instability in Epstein-Barr virus infected epithelial cells pointing to a role of co-infection in viral oncogenesis. Int J Cancer. 2019;144:98-109 pubmed 出版商
Caponegro M, Torres L, Rastegar C, Rath N, Anderson M, Robinson J, et al. Pifithrin-μ modulates microglial activation and promotes histological recovery following spinal cord injury. CNS Neurosci Ther. 2019;25:200-214 pubmed 出版商
Han W, Hu P, Wu F, Wang S, Hu Y, Li S, et al. FHL3 links cell growth and self-renewal by modulating SOX4 in glioma. Cell Death Differ. 2019;26:796-811 pubmed 出版商
Chiou B, Neal E, Bowman A, Lippmann E, Simpson I, Connor J. Endothelial cells are critical regulators of iron transport in a model of the human blood-brain barrier. J Cereb Blood Flow Metab. 2019;39:2117-2131 pubmed 出版商
Viringipurampeer I, Gregory Evans C, Metcalfe A, Bashar E, Moritz O, Gregory Evans K. Cell Death Pathways in Mutant Rhodopsin Rat Models Identifies Genotype-Specific Targets Controlling Retinal Degeneration. Mol Neurobiol. 2019;56:1637-1652 pubmed 出版商
Coronel R, Lachgar M, Bernabeu Zornoza A, Palmer C, Domínguez Alvaro M, Revilla A, et al. Neuronal and Glial Differentiation of Human Neural Stem Cells Is Regulated by Amyloid Precursor Protein (APP) Levels. Mol Neurobiol. 2019;56:1248-1261 pubmed 出版商
Zhou J, Zhu Z, Wu F, Zhou Y, Sheng R, Wu J, et al. NADPH ameliorates MPTP-induced dopaminergic neurodegeneration through inhibiting p38MAPK activation. Acta Pharmacol Sin. 2019;40:180-191 pubmed 出版商
Li B, Wang Z, Xie J, Wang G, Qian L, Guan X, et al. TIGAR knockdown enhanced the anticancer effect of aescin via regulating autophagy and apoptosis in colorectal cancer cells. Acta Pharmacol Sin. 2019;40:111-121 pubmed 出版商
Martín Hernández D, Tendilla Beltran H, Madrigal J, Garcia Bueno B, Leza J, Caso J. Chronic Mild Stress Alters Kynurenine Pathways Changing the Glutamate Neurotransmission in Frontal Cortex of Rats. Mol Neurobiol. 2019;56:490-501 pubmed 出版商
Wang H, Kira Y, Hamuro A, Takase A, Tachibana D, Koyama M. Differential gene expression of extracellular-matrix-related proteins in the vaginal apical compartment of women with pelvic organ prolapse. Int Urogynecol J. 2019;30:439-446 pubmed 出版商
Jutzi J, Kleppe M, Dias J, Staehle H, Shank K, Teruya Feldstein J, et al. LSD1 Inhibition Prolongs Survival in Mouse Models of MPN by Selectively Targeting the Disease Clone. Hemasphere. 2018;2:e54 pubmed 出版商
Hegarty S, Sullivan A, O Keeffe G. Protocol for evaluation of neurotrophic strategies in Parkinson's disease-related dopaminergic and sympathetic neurons in vitro. J Biol Methods. 2016;3:e50 pubmed 出版商
Okada R, Hara T, Sato T, Kojima N, Nishina Y. The mechanism and control of Jagged1 expression in Sertoli cells. Regen Ther. 2016;3:75-81 pubmed 出版商
Machado M, Bassani T, Cóppola Segovia V, Moura E, Zanata S, Andreatini R, et al. PPAR-γ agonist pioglitazone reduces microglial proliferation and NF-κB activation in the substantia nigra in the 6-hydroxydopamine model of Parkinson's disease. Pharmacol Rep. 2018;71:556-564 pubmed 出版商
Jolly M, Preca B, Tripathi S, Jia D, George J, Hanash S, et al. Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer. APL Bioeng. 2018;2:031908 pubmed 出版商
Lin C, Hsieh Y, Yang Y, Chen S, Wu C, Hwang L. B-Cell Lymphoma 6 (BCL6) Is a Host Restriction Factor That Can Suppress HBV Gene Expression and Modulate Immune Responses. Front Microbiol. 2018;9:3253 pubmed 出版商
Peng Z, Wang S, Gide M, Zhu D, Lamabadu Warnakulasuriya Patabendige H, Li C, et al. A Novel Bacteriophage Lysin-Human Defensin Fusion Protein Is Effective in Treatment of Clostridioides difficile Infection in Mice. Front Microbiol. 2018;9:3234 pubmed 出版商
Paarmann K, Prakash S, Krohn M, Möhle L, Brackhan M, Bruning T, et al. French maritime pine bark treatment decelerates plaque development and improves spatial memory in Alzheimer's disease mice. Phytomedicine. 2018;57:39-48 pubmed 出版商
Li X, Liang S, Li Z, Li S, Xia M, Verkhratsky A, et al. Leptin Increases Expression of 5-HT2B Receptors in Astrocytes Thus Enhancing Action of Fluoxetine on the Depressive Behavior Induced by Sleep Deprivation. Front Psychiatry. 2018;9:734 pubmed 出版商
Ali A, Kim M, Kim M, Lee H, Roh G, Kim H, et al. Quercetin induces cell death in cervical cancer by reducing O-GlcNAcylation of adenosine monophosphate-activated protein kinase. Anat Cell Biol. 2018;51:274-283 pubmed 出版商
Kaushik R, Morkovin E, Schneeberg J, Confettura A, Kreutz M, Senkov O, et al. Traditional Japanese Herbal Medicine Yokukansan Targets Distinct but Overlapping Mechanisms in Aged Mice and in the 5xFAD Mouse Model of Alzheimer's Disease. Front Aging Neurosci. 2018;10:411 pubmed 出版商
Song S, Hwang E. A Rise in ATP, ROS, and Mitochondrial Content upon Glucose Withdrawal Correlates with a Dysregulated Mitochondria Turnover Mediated by the Activation of the Protein Deacetylase SIRT1. Cells. 2018;8: pubmed 出版商
Faro J, Romero R, Schwenkel G, Garcia Flores V, Arenas Hernandez M, Leng Y, et al. Inflammation-Induced Intra-Amniotic inflammation induces preterm birth by Activating the NLRP3 inflammasome. Biol Reprod. 2018;: pubmed 出版商
Scavuzzo M, Chmielowiec J, Yang D, Wamble K, Chaboub L, Duraine L, et al. Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA. Cell Rep. 2018;25:3811-3827.e7 pubmed 出版商
Olcina M, Balanis N, Kim R, Aksoy B, Kodysh J, Thompson M, et al. Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer. Cell Rep. 2018;25:3721-3732.e6 pubmed 出版商
Mastri M, Tracz A, Lee C, Dolan M, Attwood K, Christensen J, et al. A Transient Pseudosenescent Secretome Promotes Tumor Growth after Antiangiogenic Therapy Withdrawal. Cell Rep. 2018;25:3706-3720.e8 pubmed 出版商
Granato M, Gilardini Montani M, Angiolillo C, D Orazi G, Faggioni A, Cirone M. Cytotoxic Drugs Activate KSHV Lytic Cycle in Latently Infected PEL Cells by Inducing a Moderate ROS Increase Controlled by HSF1, NRF2 and p62/SQSTM1. Viruses. 2018;11: pubmed 出版商
Chen W, Zhuo M, Lü X, Xia X, Zhao Y, Huang Z, et al. SRC-3 protects intestine from DSS-induced colitis by inhibiting inflammation and promoting goblet cell differentiation through enhancement of KLF4 expression. Int J Biol Sci. 2018;14:2051-2064 pubmed 出版商
Shi M, Duan G, Nie S, Shen S, Zou X. Elevated FAM3C promotes cell epithelial- mesenchymal transition and cell migration in gastric cancer. Onco Targets Ther. 2018;11:8491-8505 pubmed 出版商
Ramadan W, Vazhappilly C, Saleh E, Menon V, AlAzawi A, El Serafi A, et al. Interplay between Epigenetics, Expression of Estrogen Receptor- α, HER2/ERBB2 and Sensitivity of Triple Negative Breast Cancer Cells to Hormonal Therapy. Cancers (Basel). 2018;11: pubmed 出版商
Prata C, Facchini C, Leoncini E, Lenzi M, Maraldi T, Angeloni C, et al. Sulforaphane Modulates AQP8-Linked Redox Signalling in Leukemia Cells. Oxid Med Cell Longev. 2018;2018:4125297 pubmed 出版商
Selimoglu Buet D, Rivière J, Ghamlouch H, Bencheikh L, Lacout C, Morabito M, et al. A miR-150/TET3 pathway regulates the generation of mouse and human non-classical monocyte subset. Nat Commun. 2018;9:5455 pubmed 出版商
Liu Y, Yamashita J. AMPK activators contribute to maintain naïve pluripotency in mouse embryonic stem cells. Biochem Biophys Res Commun. 2018;: pubmed 出版商
Zhang X, Schönrogge M, Eichberg J, Wendt E, Kumstel S, Stenzel J, et al. Blocking Autophagy in Cancer-Associated Fibroblasts Supports Chemotherapy of Pancreatic Cancer Cells. Front Oncol. 2018;8:590 pubmed 出版商
Ortiz Rivero S, Baquero C, Hernández Cano L, Roldán Etcheverry J, Gutiérrez Herrero S, Fernández Infante C, et al. C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation. Cell Commun Signal. 2018;16:101 pubmed 出版商
Durand N, Borges S, Hall T, Bastea L, Döppler H, Edenfield B, et al. The phosphorylation status of PIP5K1C at serine 448 can be predictive for invasive ductal carcinoma of the breast. Oncotarget. 2018;9:36358-36370 pubmed 出版商
Kobayakawa Y, Masaki K, Yamasaki R, Shiraishi W, Hayashida S, Hayashi S, et al. Downregulation of Neuronal and Dendritic Connexin36-Made Electrical Synapses Without Glutamatergic Axon Terminals in Spinal Anterior Horn Cells From the Early Stage of Amyotrophic Lateral Sclerosis. Front Neurosci. 2018;12:894 pubmed 出版商
Duan G, Song Z, Qi M, Bai X, Wang J, Zhang Y, et al. Increased Autophagy Levels Mediate Cisplatin Resistance in Cisplatin-Resistant Cells While Also Rendering Them Vulnerable to Autophagy Induction. Biomed Res Int. 2018;2018:1736738 pubmed 出版商
Zheng Y, Chen B, Jiang J, Zhang J. Syntaxin 1B Mediates Berberine's Roles in Epilepsy-Like Behavior in a Pentylenetetrazole-Induced Seizure Zebrafish Model. Front Mol Neurosci. 2018;11:378 pubmed 出版商
Qi W, Chen H, Lu C, Bu Q, Wang X, Han L. BRG1 Promotes chromatin remodeling around DNA damage sites. Anim Cells Syst (Seoul). 2018;22:360-367 pubmed 出版商
Okamoto K, Ohishi T, Kuroiwa M, Iemura S, Natsume T, Seimiya H. MERIT40-dependent recruitment of tankyrase to damaged DNA and its implication for cell sensitivity to DNA-damaging anticancer drugs. Oncotarget. 2018;9:35844-35855 pubmed 出版商
Negoita F, Säll J, Morén B, Stenkula K, Göransson O. Salt-inducible kinase 2 regulates TFEB and is required for autophagic flux in adipocytes. Biochem Biophys Res Commun. 2018;: pubmed 出版商
Asampille G, Verma B, Swain M, Shettar A, Rosenzweig S, Kondaiah P, et al. An ultra-stable redox-controlled self-assembling polypeptide nanotube for targeted imaging and therapy in cancer. J Nanobiotechnology. 2018;16:101 pubmed 出版商
Zhang F, Zakaria S, Högqvist Tabor V, Singh M, Tronnersjö S, Goodwin J, et al. MYC and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts. Cell Cycle. 2018;17:2697-2715 pubmed 出版商
Pan M, Jiao S, Reinach P, Yan J, Yang Y, Li Q, et al. Opposing Effects of PPARα Agonism and Antagonism on Refractive Development and Form Deprivation Myopia in Guinea Pigs. Invest Ophthalmol Vis Sci. 2018;59:5803-5815 pubmed 出版商
Kazi A, Xiang S, Yang H, Delitto D, Trevino J, Jiang R, et al. GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors. Nat Commun. 2018;9:5154 pubmed 出版商
Bahat A, Goldman A, Zaltsman Y, Khan D, Halperin C, Amzallag E, et al. MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells. Nat Commun. 2018;9:5132 pubmed 出版商
Macmillan Crow L, Mayeux P. Female mice exhibit less renal mitochondrial injury but greater mortality using a comorbid model of experimental sepsis. Intern Med Rev (Wash D C). 2018;4: pubmed 出版商
Pinho A, Van Bulck M, Chantrill L, Arshi M, Sklyarova T, Herrmann D, et al. ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling. Nat Commun. 2018;9:5083 pubmed 出版商
Wu C, Jan Y, Ko B, Wu Y, Wu Y, Liou J. Prognostic Significance of 14-3-3ε, Aldo-keto Reductase Family 1 B10 and Metallothionein-1 in Hepatocellular Carcinoma. Anticancer Res. 2018;38:6855-6863 pubmed 出版商
Rusnak L, Tang C, Qi Q, Mo X, Fu H. Large tumor suppressor 2, LATS2, activates JNK in a kinase-independent mechanism through ASK1. J Mol Cell Biol. 2018;10:549-558 pubmed 出版商
Clayton E, Milioto C, Muralidharan B, Norona F, Edgar J, Soriano A, et al. Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown. Brain. 2018;141:3428-3442 pubmed 出版商
Wang H, Li S, Zhang H, Wang Y, Hao S, Wu X. BLM prevents instability of structure-forming DNA sequences at common fragile sites. PLoS Genet. 2018;14:e1007816 pubmed 出版商
Tertil M, Skupio U, Barut J, Dubovyk V, Wawrzczak Bargiela A, Soltys Z, et al. Glucocorticoid receptor signaling in astrocytes is required for aversive memory formation. Transl Psychiatry. 2018;8:255 pubmed 出版商
Wakx A, Nedder M, Tomkiewicz Raulet C, Dalmasso J, Chissey A, Boland S, et al. Expression, Localization, and Activity of the Aryl Hydrocarbon Receptor in the Human Placenta. Int J Mol Sci. 2018;19: pubmed 出版商
Qi Y, Wang Z, Wu F, Yin B, Jiang T, Qiang B, et al. Long noncoding RNA HOXD-AS2 regulates cell cycle to promote glioma progression. J Cell Biochem. 2018;: pubmed 出版商
Pervolaraki K, Rastgou Talemi S, Albrecht D, Bormann F, Bamford C, Mendoza J, et al. Differential induction of interferon stimulated genes between type I and type III interferons is independent of interferon receptor abundance. PLoS Pathog. 2018;14:e1007420 pubmed 出版商
Saikia P, Thangavadivel S, Medeiros C, Lassance L, de Oliveira R, Wilson S. IL-1 and TGF-β Modulation of Epithelial Basement Membrane Components Perlecan and Nidogen Production by Corneal Stromal Cells. Invest Ophthalmol Vis Sci. 2018;59:5589-5598 pubmed 出版商
Kim J, Lee Y, You Y, Moon M, Yoon K, Ahn Y, et al. Effect of sodium-glucose cotransporter 2 inhibitor, empagliflozin, and α-glucosidase inhibitor, voglibose, on hepatic steatosis in an animal model of type 2 diabetes. J Cell Biochem. 2018;: pubmed 出版商
Tzeng Y, Liu P, Li J, Liu L, Kuo S, Hsieh C, et al. Kinome-Wide siRNA Screening Identifies Src-Enhanced Resistance of Chemotherapeutic Drugs in Triple-Negative Breast Cancer Cells. Front Pharmacol. 2018;9:1285 pubmed 出版商
Mejias N, Martinez C, Stephens M, de Rivero Vaccari J. Contribution of the inflammasome to inflammaging. J Inflamm (Lond). 2018;15:23 pubmed 出版商
Choi E, Song J, Ha N, Choi Y, Kim S. CKD-506, a novel HDAC6-selective inhibitor, improves renal outcomes and survival in a mouse model of systemic lupus erythematosus. Sci Rep. 2018;8:17297 pubmed 出版商
Santana Codina N, Roeth A, Zhang Y, Yang A, Mashadova O, Asara J, et al. Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis. Nat Commun. 2018;9:4945 pubmed 出版商
Linder A, Hagberg Thulin M, Damber J, Welén K. Analysis of regulator of G-protein signalling 2 (RGS2) expression and function during prostate cancer progression. Sci Rep. 2018;8:17259 pubmed 出版商
Gao X, Lu A, Tang Y, Schneppendahl J, Liebowitz A, Scibetta A, et al. Influences of donor and host age on human muscle-derived stem cell-mediated bone regeneration. Stem Cell Res Ther. 2018;9:316 pubmed 出版商
Abdullah A, Zhang M, Frugier T, Bedoui S, Taylor J, Crack P. STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury. J Neuroinflammation. 2018;15:323 pubmed 出版商
Zhu W, Qu H, Xu K, Jia B, Li H, Du Y, et al. Differences in the starvation-induced autophagy response in MDA-MB-231 and MCF-7 breast cancer cells. Anim Cells Syst (Seoul). 2017;21:190-198 pubmed 出版商
Obr A, Kumar S, Chang Y, Bulatowicz J, Barnes B, Birge R, et al. Insulin-like growth factor receptor signaling in breast tumor epithelium protects cells from endoplasmic reticulum stress and regulates the tumor microenvironment. Breast Cancer Res. 2018;20:138 pubmed 出版商
Grun D, Adhikary G, Eckert R. NRP-1 interacts with GIPC1 and SYX to activate p38 MAPK signaling and cancer stem cell survival. Mol Carcinog. 2018;: pubmed 出版商
Voytyuk I, Mueller S, Herber J, Snellinx A, Moechars D, Van Loo G, et al. BACE2 distribution in major brain cell types and identification of novel substrates. Life Sci Alliance. 2018;1:e201800026 pubmed 出版商
Czeredys M, Vigont V, Boeva V, Mikoshiba K, Kaznacheyeva E, Kuznicki J. Huntingtin-Associated Protein 1A Regulates Store-Operated Calcium Entry in Medium Spiny Neurons From Transgenic YAC128 Mice, a Model of Huntington's Disease. Front Cell Neurosci. 2018;12:381 pubmed 出版商
Vasquez Y, Wang X, Wetendorf M, Franco H, Mo Q, Wang T, et al. FOXO1 regulates uterine epithelial integrity and progesterone receptor expression critical for embryo implantation. PLoS Genet. 2018;14:e1007787 pubmed 出版商
Kubota T, Inoue M, Kubota N, Takamoto I, Mineyama T, Iwayama K, et al. Downregulation of macrophage Irs2 by hyperinsulinemia impairs IL-4-indeuced M2a-subtype macrophage activation in obesity. Nat Commun. 2018;9:4863 pubmed 出版商
Kakuguchi W, Nomura T, Kitamura T, Otsuguro S, Matsushita K, Sakaitani M, et al. Suramin, screened from an approved drug library, inhibits HuR functions and attenuates malignant phenotype of oral cancer cells. Cancer Med. 2018;7:6269-6280 pubmed 出版商
Azatyan A, Gallo Oller G, Diao Y, Selivanova G, Johnsen J, Zaphiropoulos P. RITA downregulates Hedgehog-GLI in medulloblastoma and rhabdomyosarcoma via JNK-dependent but p53-independent mechanism. Cancer Lett. 2018;442:341-350 pubmed 出版商
Stoupa A, Adam F, Kariyawasam D, Strassel C, Gawade S, Szinnai G, et al. TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology. EMBO Mol Med. 2018;10: pubmed 出版商
Brandt C, Nolte H, Henschke S, Engström Ruud L, Awazawa M, Morgan D, et al. Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation. Cell. 2018;175:1321-1335.e20 pubmed 出版商
Lee J, Kim H, Kim J, Park K, Kim D, Hwang O. The Novel Neuroprotective Compound KMS99220 Has an Early Anti-neuroinflammatory Effect via AMPK and HO-1, Independent of Nrf2. Exp Neurobiol. 2018;27:408-418 pubmed 出版商
Han F, Li C, Cai Z, Zhang X, Jin G, Zhang W, et al. The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance. Nat Commun. 2018;9:4728 pubmed 出版商
Franco Iborra S, Cuadros T, Parent A, Romero Gimenez J, Vila M, Perier C. Defective mitochondrial protein import contributes to complex I-induced mitochondrial dysfunction and neurodegeneration in Parkinson's disease. Cell Death Dis. 2018;9:1122 pubmed 出版商
Moll L, Roitenberg N, Bejerano Sagie M, Boocholez H, Carvalhal Marques F, Volovik Y, et al. The insulin/IGF signaling cascade modulates SUMOylation to regulate aging and proteostasis in Caenorhabditis elegans. elife. 2018;7: pubmed 出版商
Deng Y, Pakdel M, Blank B, Sundberg E, Burd C, von Blume J. Activity of the SPCA1 Calcium Pump Couples Sphingomyelin Synthesis to Sorting of Secretory Proteins in the Trans-Golgi Network. Dev Cell. 2018;47:464-478.e8 pubmed 出版商
Barikbin R, Berkhout L, Bolik J, Schmidt Arras D, Ernst T, Ittrich H, et al. Early heme oxygenase 1 induction delays tumour initiation and enhances DNA damage repair in liver macrophages of Mdr2-/- mice. Sci Rep. 2018;8:16238 pubmed 出版商
Wang F, Chen S, Liu H, Parent C, Coulombe P. Keratin 6 regulates collective keratinocyte migration by altering cell-cell and cell-matrix adhesion. J Cell Biol. 2018;217:4314-4330 pubmed 出版商
Löffler M, Mayer A, Trujillo Viera J, Loza Valdes A, El Merahbi R, Ade C, et al. Protein kinase D1 deletion in adipocytes enhances energy dissipation and protects against adiposity. EMBO J. 2018;37: pubmed 出版商
Cho E, Lee J, Lee J, Chen Z, Ahn S, Kim N, et al. BCPA {N,N'-1,4-Butanediylbis[3-(2-chlorophenyl)acrylamide]} Inhibits Osteoclast Differentiation through Increased Retention of Peptidyl-Prolyl cis-trans Isomerase Never in Mitosis A-Interacting 1. Int J Mol Sci. 2018;19: pubmed 出版商
Hu D, Jablonowski C, Cheng P, AlTahan A, Li C, Wang Y, et al. KDM5A Regulates a Translational Program that Controls p53 Protein Expression. iScience. 2018;9:84-100 pubmed 出版商
Boehm V, Britto Borges T, Steckelberg A, Singh K, Gerbracht J, Gueney E, et al. Exon Junction Complexes Suppress Spurious Splice Sites to Safeguard Transcriptome Integrity. Mol Cell. 2018;72:482-495.e7 pubmed 出版商
Cozza G, Moro E, Black M, Marin O, Salvi M, Venerando A, et al. The Golgi 'casein kinase' Fam20C is a genuine 'phosvitin kinase' and phosphorylates polyserine stretches devoid of the canonical consensus. FEBS J. 2018;285:4674-4683 pubmed 出版商
Stenzel P, Nagorsen K, Bernd J, Leppert U, Zakrzewicz A, Berkholz J. ZNF580 - a brake on Interleukin-6. J Inflamm (Lond). 2018;15:20 pubmed 出版商
Lincoln F, Imig D, Boccellato C, Juric V, Noonan J, Kontermann R, et al. Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism. Cell Death Dis. 2018;9:1112 pubmed 出版商
Song Y, Kim I, Choi I, Kim S, Seo H. Oxytetracycline have the therapeutic efficiency in CD133+ HCC population through suppression CD133 expression by decreasing of protein stability of CD133. Sci Rep. 2018;8:16100 pubmed 出版商
Henss L, Scholz T, Grünweller A, Schnierle B. Silvestrol Inhibits Chikungunya Virus Replication. Viruses. 2018;10: pubmed 出版商
De Donato M, Righino B, Filippetti F, Battaglia A, Petrillo M, Pirolli D, et al. Identification and antitumor activity of a novel inhibitor of the NIMA-related kinase NEK6. Sci Rep. 2018;8:16047 pubmed 出版商
Gu D, Lin H, Zhang X, Fan Q, Chen S, Shahda S, et al. Simultaneous Inhibition of MEK and Hh Signaling Reduces Pancreatic Cancer Metastasis. Cancers (Basel). 2018;10: pubmed 出版商
Kwon S, Kim Y, Jang H, Seo Y. Synergistic effect of rice bran extract and extremely low-frequency electromagnetic fields on dermal papilla/melanocytes in melanogenesis. Bioelectromagnetics. 2018;39:595-603 pubmed 出版商
Warren J, Im M, Ballesteros A, Ha C, Moore T, Lambert F, et al. Act