产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
产品类型 :
抗体
产品名称 :
Monoclonal Anti-β-Actin antibody produced in mouse
目录 :
A5441
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AC-15
反应物种 :
African green monkey, 仓鼠, zebra finch, Burton's mouthbrooder, Garra rufa, 人类, 小鼠, 大鼠, , , , pigs , 斑马鱼, fruit fly , 家羊, domestic rabbit
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, 其他, 免疫印迹基因敲除验证, 免疫组化基因敲除验证, 免疫细胞化学基因敲除验证
更多信息或购买 :
文章摘录数: 6505
出版应用/物种/样本/稀释参考文献
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Pi H, Li M, Tian L, Yang Z, Yu Z, Zhou Z. Enhancing lysosomal biogenesis and autophagic flux by activating the transcription factor EB protects against cadmium-induced neurotoxicity. Sci Rep. 2017;7:43466 pubmed 出版商
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Patrinostro X, O Rourke A, Chamberlain C, Moriarity B, Perrin B, Ervasti J. Relative importance of ?cyto- and ?cyto-actin in primary mouse embryonic fibroblasts. Mol Biol Cell. 2017;28:771-782 pubmed 出版商
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Natarajan S, Muthukrishnan E, Khalimonchuk O, Mott J, Becker D. Evidence for Pipecolate Oxidase in Mediating Protection Against Hydrogen Peroxide Stress. J Cell Biochem. 2017;118:1678-1688 pubmed 出版商
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Wizeman J, Nicholas A, Ishigami A, Mohan R. Citrullination of glial intermediate filaments is an early response in retinal injury. Mol Vis. 2016;22:1137-1155 pubmed
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Barão S, Gärtner A, Leyva Díaz E, Demyanenko G, Munck S, Vanhoutvin T, et al. Antagonistic Effects of BACE1 and APH1B-γ-Secretase Control Axonal Guidance by Regulating Growth Cone Collapse. Cell Rep. 2015;12:1367-76 pubmed 出版商
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Gramolelli S, Weidner Glunde M, Abere B, Viejo Borbolla A, Bala K, Rückert J, et al. Inhibiting the Recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells. PLoS Pathog. 2015;11:e1005105 pubmed 出版商
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Lee Y, Liu C, Liao M, Sukhova G, Shirakawa J, Abdennour M, et al. Deficiency of FcϵR1 Increases Body Weight Gain but Improves Glucose Tolerance in Diet-Induced Obese Mice. Endocrinology. 2015;156:4047-58 pubmed 出版商
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Fritz H, Gustafsson A, Ljungberg B, Ceder Y, Axelson H, Dahlbäck B. The Axl-Regulating Tumor Suppressor miR-34a Is Increased in ccRCC but Does Not Correlate with Axl mRNA or Axl Protein Levels. PLoS ONE. 2015;10:e0135991 pubmed 出版商
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Galicia Vázquez G, Chu J, Pelletier J. eIF4AII is dispensable for miRNA-mediated gene silencing. RNA. 2015;21:1826-33 pubmed 出版商
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Fan L, Peng G, Sahgal N, Fazli L, Gleave M, Zhang Y, et al. Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival. Oncogene. 2016;35:2441-52 pubmed 出版商
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Lim T, Lee I, Kim J, Kang W. Synergistic Effect of Simvastatin Plus Radiation in Gastric Cancer and Colorectal Cancer: Implications of BIRC5 and Connective Tissue Growth Factor. Int J Radiat Oncol Biol Phys. 2015;93:316-25 pubmed 出版商
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Steingruber M, Socher E, Hutterer C, Webel R, Bergbrede T, Lenac T, et al. The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain. Viruses. 2015;7:4582-601 pubmed 出版商
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Zhen Y, Li W. Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33A(D251E) mutation. Autophagy. 2015;11:1608-22 pubmed 出版商
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Genin M, Clement F, Fattaccioli A, Raes M, Michiels C. M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide. BMC Cancer. 2015;15:577 pubmed 出版商
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Ju X, Yan Y, Liu Q, Li N, Sheng M, Zhang L, et al. Neuraminidase of Influenza A Virus Binds Lysosome-Associated Membrane Proteins Directly and Induces Lysosome Rupture. J Virol. 2015;89:10347-58 pubmed 出版商
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Lutzenberger M, Burwinkel M, Riemer C, Bode V, Baier M. Ablation of CCAAT/Enhancer-Binding Protein Delta (C/EBPD): Increased Plaque Burden in a Murine Alzheimer's Disease Model. PLoS ONE. 2015;10:e0134228 pubmed 出版商
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Verrier E, Colpitts C, Bach C, Heydmann L, Weiss A, Renaud M, et al. A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses. Hepatology. 2016;63:35-48 pubmed 出版商
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Chen C, Tian F, Lu L, Wang Y, Xiao Z, Yu C, et al. Characterization of Cep85 - a new antagonist of Nek2A that is involved in the regulation of centrosome disjunction. J Cell Sci. 2015;128:3290-303 pubmed 出版商
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Roncero A, López Nieva P, Cobos Fernández M, Villa Morales M, González Sánchez L, López Lorenzo J, et al. Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development. Leukemia. 2016;30:94-103 pubmed 出版商
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Prasad S, Sajja R, Park J, Naik P, Kaisar M, Cucullo L. Impact of cigarette smoke extract and hyperglycemic conditions on blood-brain barrier endothelial cells. Fluids Barriers CNS. 2015;12:18 pubmed 出版商
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He D, Chen H, Muramatsu H, Lasek A. Ethanol activates midkine and anaplastic lymphoma kinase signaling in neuroblastoma cells and in the brain. J Neurochem. 2015;135:508-21 pubmed 出版商
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Gingras S, Earls L, Howell S, Smeyne R, Zakharenko S, Pelletier S. SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus. J Neurosci. 2015;35:10510-22 pubmed 出版商
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Kreit M, Vertommen D, Gillet L, Michiels T. The Interferon-Inducible Mouse Apolipoprotein L9 and Prohibitins Cooperate to Restrict Theiler's Virus Replication. PLoS ONE. 2015;10:e0133190 pubmed 出版商
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Yang Y, Liu Z, Wang F, Temviriyanukul P, Ma X, Tu Y, et al. FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress. Nucleic Acids Res. 2015;43:8325-39 pubmed 出版商
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Chiou S, Winters I, Wang J, Naranjo S, Dudgeon C, Tamburini F, et al. Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing. Genes Dev. 2015;29:1576-85 pubmed 出版商
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Zhang F, Patel D, Colavita K, Rodionova I, Buckley B, Scott D, et al. Arginylation regulates purine nucleotide biosynthesis by enhancing the activity of phosphoribosyl pyrophosphate synthase. Nat Commun. 2015;6:7517 pubmed 出版商
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Hobbs R, DePianto D, Jacob J, Han M, Chung B, Batazzi A, et al. Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes. Nat Genet. 2015;47:933-8 pubmed 出版商
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Wu H, Barik A, Lu Y, Shen C, Bowman A, Li L, et al. Slit2 as a β-catenin/Ctnnb1-dependent retrograde signal for presynaptic differentiation. elife. 2015;4: pubmed 出版商
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Maggiorani D, Dissard R, Belloy M, Saulnier Blache J, Casemayou A, Ducassé L, et al. Shear Stress-Induced Alteration of Epithelial Organization in Human Renal Tubular Cells. PLoS ONE. 2015;10:e0131416 pubmed 出版商
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Yang F, Silber S, Leu N, Oates R, Marszalek J, Skaletsky H, et al. TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse. EMBO Mol Med. 2015;7:1198-210 pubmed 出版商
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Sadaie M, Dillon C, Narita M, Young A, Cairney C, Godwin L, et al. Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition. Mol Biol Cell. 2015;26:2971-85 pubmed 出版商
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Thatcher S, Zhang X, Woody S, Wang Y, Alsiraj Y, Charnigo R, et al. Exogenous 17-β estradiol administration blunts progression of established angiotensin II-induced abdominal aortic aneurysms in female ovariectomized mice. Biol Sex Differ. 2015;6:12 pubmed 出版商
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Sive J, Basilico S, Hannah R, Kinston S, Calero Nieto F, Göttgens B. Genome-scale definition of the transcriptional programme associated with compromised PU.1 activity in acute myeloid leukaemia. Leukemia. 2016;30:14-23 pubmed 出版商
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Huygens C, Liénart S, Dedobbeleer O, Stockis J, Gauthy E, Coulie P, et al. Lysosomal-associated Transmembrane Protein 4B (LAPTM4B) Decreases Transforming Growth Factor β1 (TGF-β1) Production in Human Regulatory T Cells. J Biol Chem. 2015;290:20105-16 pubmed 出版商
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Zhang J, Gao Q, Zhou Y, Dier U, Hempel N, Hochwald S. Focal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis. Oncogene. 2016;35:1926-42 pubmed 出版商
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Goichon A, Bertrand J, Chan P, Lecleire S, Coquard A, Cailleux A, et al. Enteral delivery of proteins enhances the expression of proteins involved in the cytoskeleton and protein biosynthesis in human duodenal mucosa. Am J Clin Nutr. 2015;102:359-67 pubmed 出版商
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Zhang J, Li L, Baldwin A, Friedman A, Paz Priel I. Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells. PLoS ONE. 2015;10:e0130441 pubmed 出版商
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Pishas K, Adwal A, Neuhaus S, Clayer M, Farshid G, Staudacher A, et al. XI-006 induces potent p53-independent apoptosis in Ewing sarcoma. Sci Rep. 2015;5:11465 pubmed 出版商
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Loveless T, Topacio B, Vashisht A, Galaang S, Ulrich K, Young B, et al. DNA Damage Regulates Translation through β-TRCP Targeting of CReP. PLoS Genet. 2015;11:e1005292 pubmed 出版商
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Lu H, Xue Y, Xue Y, Yu G, Arias C, Lin J, et al. Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism. elife. 2015;4:e06535 pubmed 出版商
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Liu G, Wang Z, Wang Z, Yang D, Liu Z, Wang L. Mitochondrial permeability transition and its regulatory components are implicated in apoptosis of primary cultures of rat proximal tubular cells exposed to lead. Arch Toxicol. 2016;90:1193-209 pubmed 出版商
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Whalley H, Porter A, Diamantopoulou Z, White G, Castañeda Saucedo E, Malliri A. Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation. Nat Commun. 2015;6:7437 pubmed 出版商
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Specks J, Lecona E, Lopez Contreras A, Fernandez Capetillo O. A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development. Mol Cell Biol. 2015;35:2910-7 pubmed 出版商
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Preca B, Bajdak K, Mock K, Sundararajan V, Pfannstiel J, Maurer J, et al. A self-enforcing CD44s/ZEB1 feedback loop maintains EMT and stemness properties in cancer cells. Int J Cancer. 2015;137:2566-77 pubmed 出版商
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Stermann A, Huebener N, Seidel D, Fest S, Eschenburg G, Stauder M, et al. Targeting of MYCN by means of DNA vaccination is effective against neuroblastoma in mice. Cancer Immunol Immunother. 2015;64:1215-27 pubmed 出版商
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Su Y, Chang Y, Lin W, Liang C, Lee J. An aberrant nuclear localization of E-cadherin is a potent inhibitor of Wnt/β-catenin-elicited promotion of the cancer stem cell phenotype. Oncogenesis. 2015;4:e157 pubmed 出版商
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Bijata M, Wlodarczyk J, Figiel I. Dystroglycan controls dendritic morphogenesis of hippocampal neurons in vitro. Front Cell Neurosci. 2015;9:199 pubmed 出版商
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Cerella C, Muller F, Gaigneaux A, Radogna F, Viry E, Chateauvieux S, et al. Early downregulation of Mcl-1 regulates apoptosis triggered by cardiac glycoside UNBS1450. Cell Death Dis. 2015;6:e1782 pubmed 出版商
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Wagenknecht N, Reuter N, Scherer M, Reichel A, Müller R, Stamminger T. Contribution of the Major ND10 Proteins PML, hDaxx and Sp100 to the Regulation of Human Cytomegalovirus Latency and Lytic Replication in the Monocytic Cell Line THP-1. Viruses. 2015;7:2884-907 pubmed 出版商
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Dille S, Kleinschnitz E, Kontchou C, Nölke T, Häcker G. In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transport. Infect Immun. 2015;83:3268-80 pubmed 出版商
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von Einem B, Wahler A, Schips T, Serrano Pozo A, Proepper C, Boeckers T, et al. The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1). PLoS ONE. 2015;10:e0129047 pubmed 出版商
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Holtzhausen A, Zhao F, Evans K, Tsutsui M, Orabona C, Tyler D, et al. Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy. Cancer Immunol Res. 2015;3:1082-95 pubmed 出版商
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Subathra M, Korrapati M, Howell L, Arthur J, Shayman J, Schnellmann R, et al. Kidney glycosphingolipids are elevated early in diabetic nephropathy and mediate hypertrophy of mesangial cells. Am J Physiol Renal Physiol. 2015;309:F204-15 pubmed 出版商
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Castiglioni A, Corna G, Rigamonti E, Basso V, Vezzoli M, Monno A, et al. FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration. PLoS ONE. 2015;10:e0128094 pubmed 出版商
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Hayashi T, Wills S, Bussey K, Takimoto T. Identification of Influenza A Virus PB2 Residues Involved in Enhanced Polymerase Activity and Virus Growth in Mammalian Cells at Low Temperatures. J Virol. 2015;89:8042-9 pubmed 出版商
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Reigada D, Nieto Díaz M, Navarro Ruiz R, Caballero López M, Del Águila A, Muñoz Galdeano T, et al. Acute administration of ucf-101 ameliorates the locomotor impairments induced by a traumatic spinal cord injury. Neuroscience. 2015;300:404-17 pubmed 出版商
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Suárez Causado A, Caballero Díaz D, Bertrán E, Roncero C, Addante A, García Álvaro M, et al. HGF/c-Met signaling promotes liver progenitor cell migration and invasion by an epithelial-mesenchymal transition-independent, phosphatidyl inositol-3 kinase-dependent pathway in an in vitro model. Biochim Biophys Acta. 2015;1853:2453-63 pubmed 出版商
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Peng B, Wang J, Hu Y, Zhao H, Hou W, Zhao H, et al. Modulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damage. Nucleic Acids Res. 2015;43:5936-47 pubmed 出版商
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Fischer S, Paul A, Wagner A, Mathias S, Geiss M, Schandock F, et al. miR-2861 as novel HDAC5 inhibitor in CHO cells enhances productivity while maintaining product quality. Biotechnol Bioeng. 2015;112:2142-53 pubmed 出版商
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Moon J, Eo S, Lee J, Park S. Quercetin-induced autophagy flux enhances TRAIL-mediated tumor cell death. Oncol Rep. 2015;34:375-81 pubmed 出版商
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Yufune S, Satoh Y, Takamatsu I, Ohta H, Kobayashi Y, Takaenoki Y, et al. Transient Blockade of ERK Phosphorylation in the Critical Period Causes Autistic Phenotypes as an Adult in Mice. Sci Rep. 2015;5:10252 pubmed 出版商
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Wang Z, Ma B, Ji X, Deng Y, Zhang T, Zhang X, et al. MicroRNA-378-5p suppresses cell proliferation and induces apoptosis in colorectal cancer cells by targeting BRAF. Cancer Cell Int. 2015;15:40 pubmed 出版商
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Noss E, Watts G, Zocco D, Keller T, Whitman M, Blobel C, et al. Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism. Arthritis Res Ther. 2015;17:126 pubmed 出版商
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Bergeron D, Pal G, Beaulieu Y, Chabot B, Bachand F. Regulated Intron Retention and Nuclear Pre-mRNA Decay Contribute to PABPN1 Autoregulation. Mol Cell Biol. 2015;35:2503-17 pubmed 出版商
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Tanas M, Ma S, Jadaan F, Ng C, Weigelt B, Reis Filho J, et al. Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein. Oncogene. 2016;35:929-38 pubmed 出版商
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Fujikawa Y, Tominaga K, Tanaka F, Tanigawa T, Watanabe T, Fujiwara Y, et al. Enteric glial cells are associated with stress-induced colonic hyper-contraction in maternally separated rats. Neurogastroenterol Motil. 2015;27:1010-23 pubmed 出版商
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Barrett K, Fang H, Cukovic D, Dombkowski A, Kocarek T, Runge Morris M. Upregulation of UGT2B4 Expression by 3'-Phosphoadenosine-5'-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid Conjugation. Drug Metab Dispos. 2015;43:1061-70 pubmed 出版商
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Milenkovic A, Brandl C, Milenkovic V, Jendryke T, Sirianant L, Wanitchakool P, et al. Bestrophin 1 is indispensable for volume regulation in human retinal pigment epithelium cells. Proc Natl Acad Sci U S A. 2015;112:E2630-9 pubmed 出版商
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Fisher M, Keillor J, Xu W, Eckert R, Kerr C. Transglutaminase Is Required for Epidermal Squamous Cell Carcinoma Stem Cell Survival. Mol Cancer Res. 2015;13:1083-94 pubmed 出版商
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Bhushan S, Tchatalbachev S, Lu Y, Fröhlich S, Fijak M, Vijayan V, et al. Differential activation of inflammatory pathways in testicular macrophages provides a rationale for their subdued inflammatory capacity. J Immunol. 2015;194:5455-64 pubmed 出版商
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Yang N, Tan S, Ng S, Shi Y, Zhou J, Tan K, et al. Artesunate induces cell death in human cancer cells via enhancing lysosomal function and lysosomal degradation of ferritin. J Biol Chem. 2014;289:33425-41 pubmed 出版商
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Lupino E, Ramondetti C, Buccinnà B, Piccinini M. Exposure of neuroblastoma cell lines to imatinib results in the upregulation of the CDK inhibitor p27(KIP1) as a consequence of c-Abl inhibition. Biochem Pharmacol. 2014;92:235-50 pubmed 出版商
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Ahn J, Ruiz P, Barber G. Intrinsic self-DNA triggers inflammatory disease dependent on STING. J Immunol. 2014;193:4634-42 pubmed 出版商
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Chang Y, Huang Y. Arsenite-activated JNK signaling enhances CPEB4-Vinexin interaction to facilitate stress granule assembly and cell survival. PLoS ONE. 2014;9:e107961 pubmed 出版商
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Jebelli J, Hooper C, Pocock J. Microglial p53 activation is detrimental to neuronal synapses during activation-induced inflammation: Implications for neurodegeneration. Neurosci Lett. 2014;583:92-7 pubmed 出版商
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Kelsey L, Katoch P, Ray A, Mitra S, Chakraborty S, Lin M, et al. Vitamin D3 regulates the formation and degradation of gap junctions in androgen-responsive human prostate cancer cells. PLoS ONE. 2014;9:e106437 pubmed 出版商
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Yamasaki T, Suzuki A, Hasebe R, Horiuchi M. Comparison of the anti-prion mechanism of four different anti-prion compounds, anti-PrP monoclonal antibody 44B1, pentosan polysulfate, chlorpromazine, and U18666A, in prion-infected mouse neuroblastoma cells. PLoS ONE. 2014;9:e106516 pubmed 出版商
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Chau M, Deveau T, Song M, Gu X, Chen D, Wei L. iPSC Transplantation increases regeneration and functional recovery after ischemic stroke in neonatal rats. Stem Cells. 2014;32:3075-87 pubmed 出版商
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Bae J, Lee S, Park C, Lee Y, Chun T. Trafficking of LAG-3 to the surface on activated T cells via its cytoplasmic domain and protein kinase C signaling. J Immunol. 2014;193:3101-12 pubmed 出版商
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Baek J, Kim J, Cheon Y, Park S, Ahn S, Yoon K, et al. Aconitum pseudo-laeve var. erectum inhibits receptor activator of nuclear factor kappa-B ligand-induced osteoclastogenesis via the c-Fos/nuclear factor of activated T-cells, cytoplasmic 1 signaling pathway and prevents lipopolysaccharide-induced bone. Molecules. 2014;19:11628-44 pubmed 出版商
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Viceconte N, McKenna T, Eriksson M. Low levels of the reverse transactivator fail to induce target transgene expression in vascular smooth muscle cells. PLoS ONE. 2014;9:e104098 pubmed 出版商
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Gonzalez Rodriguez A, Reibert B, Amann T, Constien R, Rondinone C, Valverde A. In vivo siRNA delivery of Keap1 modulates death and survival signaling pathways and attenuates concanavalin-A-induced acute liver injury in mice. Dis Model Mech. 2014;7:1093-100 pubmed 出版商
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Sadleir K, Eimer W, Kaufman R, Osten P, Vassar R. Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease. PLoS ONE. 2014;9:e101643 pubmed 出版商
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Samartzis E, Gutsche K, Dedes K, Fink D, Stucki M, Imesch P. Loss of ARID1A expression sensitizes cancer cells to PI3K- and AKT-inhibition. Oncotarget. 2014;5:5295-303 pubmed
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Zhao Z, Wu L, Xiong R, Wang L, Zhang B, Wang C, et al. MicroRNA-922 promotes tau phosphorylation by downregulating ubiquitin carboxy-terminal hydrolase L1 (UCHL1) expression in the pathogenesis of Alzheimer's disease. Neuroscience. 2014;275:232-7 pubmed 出版商
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Tanaka T, Iino M. Sec6 regulated cytoplasmic translocation and degradation of p27 via interactions with Jab1 and Siah1. Cell Signal. 2014;26:2071-85 pubmed 出版商
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Herrera A, Saade M, Menendez A, Marti E, Pons S. Sustained Wnt/?-catenin signalling causes neuroepithelial aberrations through the accumulation of aPKC at the apical pole. Nat Commun. 2014;5:4168 pubmed 出版商
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Cheshenko N, Trepanier J, González P, Eugenin E, Jacobs W, Herold B. Herpes simplex virus type 2 glycoprotein H interacts with integrin ?v?3 to facilitate viral entry and calcium signaling in human genital tract epithelial cells. J Virol. 2014;88:10026-38 pubmed 出版商
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Price D, Ackland M, Burks W, Knight M, Suphioglu C. Peanut allergens alter intestinal barrier permeability and tight junction localisation in Caco-2 cell cultures. Cell Physiol Biochem. 2014;33:1758-77 pubmed 出版商
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Kaneko Y, Ota A, Nakashima A, Nagasaki H, Kodani Y, Mori K, et al. Lipopolysaccharide treatment arrests the cell cycle of BV-2 microglial cells in G? phase and protects them from UV light-induced apoptosis. J Neural Transm (Vienna). 2015;122:187-99 pubmed 出版商
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Etnyre D, Stone A, Fong J, Jacobs R, Uppada S, Botting G, et al. Targeting c-Met in melanoma: mechanism of resistance and efficacy of novel combinatorial inhibitor therapy. Cancer Biol Ther. 2014;15:1129-41 pubmed 出版商
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van Doremalen N, Miazgowicz K, Milne Price S, Bushmaker T, Robertson S, Scott D, et al. Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4. J Virol. 2014;88:9220-32 pubmed 出版商
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Devi L, Ohno M. PERK mediates eIF2? phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease. Neurobiol Aging. 2014;35:2272-81 pubmed 出版商
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Fausther M, Lavoie E, Goree J, Baldini G, Dranoff J. NT5E mutations that cause human disease are associated with intracellular mistrafficking of NT5E protein. PLoS ONE. 2014;9:e98568 pubmed 出版商
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Kodama T, Tsukaguchi T, Yoshida M, Kondoh O, Sakamoto H. Selective ALK inhibitor alectinib with potent antitumor activity in models of crizotinib resistance. Cancer Lett. 2014;351:215-21 pubmed 出版商
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Cho M, Kwon S, Kim C, Lee Y, Nam H, Lee S. Overexpression of KAI1 Protein in Diabetic Skin Tissues. Arch Plast Surg. 2014;41:248-52 pubmed 出版商
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Kadota S, Nagata K. Silencing of IFN-stimulated gene transcription is regulated by histone H1 and its chaperone TAF-I. Nucleic Acids Res. 2014;42:7642-53 pubmed 出版商
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Zeng L, Holly J, Perks C. Effects of physiological levels of the green tea extract epigallocatechin-3-gallate on breast cancer cells. Front Endocrinol (Lausanne). 2014;5:61 pubmed 出版商
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Maas N, Singh N, Diehl J. Generation and characterization of an analog-sensitive PERK allele. Cancer Biol Ther. 2014;15:1106-11 pubmed 出版商
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Israelow B, Narbus C, Sourisseau M, Evans M. HepG2 cells mount an effective antiviral interferon-lambda based innate immune response to hepatitis C virus infection. Hepatology. 2014;60:1170-9 pubmed 出版商
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Kitagawa K, Shibata K, Matsumoto A, Matsumoto M, Ohhata T, Nakayama K, et al. Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development. Mol Cell Biol. 2014;34:2732-44 pubmed
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Li C, Egloff A, Sen M, Grandis J, Johnson D. Caspase-8 mutations in head and neck cancer confer resistance to death receptor-mediated apoptosis and enhance migration, invasion, and tumor growth. Mol Oncol. 2014;8:1220-30 pubmed 出版商
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Sreedharan R, Chen S, Miller M, Haribhai D, Williams C, Van Why S. Mice with an absent stress response are protected against ischemic renal injury. Kidney Int. 2014;86:515-24 pubmed 出版商
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Senkiv Y, Riabtseva A, Heffeter P, Boiko N, Kowol C, Jungwith U, et al. Enhanced anticancer activity and circumvention of resistance mechanisms by novel polymeric/ phospholipidic nanocarriers of doxorubicin. J Biomed Nanotechnol. 2014;10:1369-81 pubmed
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Brandl C, Zimmermann S, Milenkovic V, Rosendahl S, Grassmann F, Milenkovic A, et al. In-depth characterisation of Retinal Pigment Epithelium (RPE) cells derived from human induced pluripotent stem cells (hiPSC). Neuromolecular Med. 2014;16:551-64 pubmed 出版商
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Jacob A, Singh R, Mohammad F, Bebee T, Chandler D. The splicing factor FUBP1 is required for the efficient splicing of oncogene MDM2 pre-mRNA. J Biol Chem. 2014;289:17350-64 pubmed 出版商
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Gruol D, Vo K, Bray J, Roberts A. CCL2-ethanol interactions and hippocampal synaptic protein expression in a transgenic mouse model. Front Integr Neurosci. 2014;8:29 pubmed 出版商
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Klaus C, Kaemmerer E, Reinartz A, Schneider U, Plum P, Jeon M, et al. TP53 status regulates ACSL5-induced expression of mitochondrial mortalin in enterocytes and colorectal adenocarcinomas. Cell Tissue Res. 2014;357:267-78 pubmed 出版商
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Coomans de Brachène A, Bollaert E, Eijkelenboom A, de Rocca Serra A, van der Vos K, Burgering B, et al. The expression of the tumour suppressor HBP1 is down-regulated by growth factors via the PI3K/PKB/FOXO pathway. Biochem J. 2014;460:25-34 pubmed 出版商
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Qi Y, Zhang M, Li H, Frank J, Dai L, Liu H, et al. MicroRNA-29b regulates ethanol-induced neuronal apoptosis in the developing cerebellum through SP1/RAX/PKR cascade. J Biol Chem. 2014;289:10201-10 pubmed 出版商
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Muenyi C, Trivedi A, Helm C, States J. Cisplatin plus sodium arsenite and hyperthermia induces pseudo-G1 associated apoptotic cell death in ovarian cancer cells. Toxicol Sci. 2014;139:74-82 pubmed 出版商
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Kilander M, Petersen J, Andressen K, Ganji R, Levy F, Schuster J, et al. Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6. FASEB J. 2014;28:2293-305 pubmed 出版商
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Matthess Y, Raab M, Knecht R, Becker S, Strebhardt K. Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis. Mol Oncol. 2014;8:596-608 pubmed 出版商
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Dhar S, Alam H, Li N, Wagner K, Chung J, Ahn Y, et al. Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells. J Biol Chem. 2014;289:7483-96 pubmed 出版商
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Tuttle T, Hugo E, Tong W, Ben Jonathan N. Placental lactogen is expressed but is not translated into protein in breast cancer. PLoS ONE. 2014;9:e87325 pubmed 出版商
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Jordan N, Dutkowski C, Barrow D, Mottram H, Hutcheson I, Nicholson R, et al. Impact of dual mTORC1/2 mTOR kinase inhibitor AZD8055 on acquired endocrine resistance in breast cancer in vitro. Breast Cancer Res. 2014;16:R12 pubmed 出版商
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Kempf A, Tews B, Arzt M, Weinmann O, Obermair F, Pernet V, et al. The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. PLoS Biol. 2014;12:e1001763 pubmed 出版商
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Massimino M, Consoli M, Mesuraca M, Stagno F, Tirrò E, Stella S, et al. IRF5 is a target of BCR-ABL kinase activity and reduces CML cell proliferation. Carcinogenesis. 2014;35:1132-43 pubmed 出版商
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Wadosky K, Rodriguez J, Hite R, Min J, Walton B, Willis M. Muscle RING finger-1 attenuates IGF-I-dependent cardiomyocyte hypertrophy by inhibiting JNK signaling. Am J Physiol Endocrinol Metab. 2014;306:E723-39 pubmed 出版商
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Syedain Z, Meier L, Lahti M, Johnson S, Tranquillo R. Implantation of completely biological engineered grafts following decellularization into the sheep femoral artery. Tissue Eng Part A. 2014;20:1726-34 pubmed 出版商
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Moore R, Tao W, Meng Y, Smith E, Xu X. Cell adhesion and sorting in embryoid bodies derived from N- or E-cadherin deficient murine embryonic stem cells. Biol Open. 2014;3:121-8 pubmed 出版商
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Heyne K, Förster J, Schüle R, Roemer K. Transcriptional repressor NIR interacts with the p53-inhibiting ubiquitin ligase MDM2. Nucleic Acids Res. 2014;42:3565-79 pubmed 出版商
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Stahlschmidt W, Robertson M, Robinson P, McCluskey A, Haucke V. Clathrin terminal domain-ligand interactions regulate sorting of mannose 6-phosphate receptors mediated by AP-1 and GGA adaptors. J Biol Chem. 2014;289:4906-18 pubmed 出版商
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Ziegler A, Chidambaram S, Forbes B, Wood T, Levison S. Insulin-like growth factor-II (IGF-II) and IGF-II analogs with enhanced insulin receptor-a binding affinity promote neural stem cell expansion. J Biol Chem. 2014;289:4626-33 pubmed 出版商
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Ahn J, Jang J, Choi J, Lee J, Oh S, Lee J, et al. GSK3?, but not GSK3?, inhibits the neuronal differentiation of neural progenitor cells as a downstream target of mammalian target of rapamycin complex1. Stem Cells Dev. 2014;23:1121-33 pubmed 出版商
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Basu S, Rajakaruna S, De Arcangelis A, Zhang L, Georges Labouesse E, Menko A. ?6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation. J Biol Chem. 2014;289:3842-55 pubmed 出版商
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Borghgraef P, Menuet C, Theunis C, Louis J, Devijver H, Maurin H, et al. Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice. PLoS ONE. 2013;8:e84442 pubmed 出版商
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Sahlberg S, Gustafsson A, Pendekanti P, Glimelius B, Stenerlow B. The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines. Tumour Biol. 2014;35:3525-34 pubmed 出版商
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Sharma Walia N, Chandran K, Patel K, Veettil M, Marginean A. The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis. J Virol. 2014;88:2131-56 pubmed 出版商
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Feng Y, Wu H, Xu Y, Zhang Z, Liu T, Lin X, et al. Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-? signaling. J Biol Chem. 2014;289:2072-83 pubmed 出版商
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Wu C, Ko J, Chen S, Lin Y, Han C, Yang T, et al. Clinical implications of aldo-keto reductase family 1 member C3 and its relationship with lipocalin 2 in cancer of the uterine cervix. Gynecol Oncol. 2014;132:474-82 pubmed 出版商
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Holtzhausen A, Golzio C, How T, Lee Y, Schiemann W, Katsanis N, et al. Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development. FASEB J. 2014;28:1248-67 pubmed 出版商
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Wagner M, Koslowski M, Paret C, Schmidt M, Tureci O, Sahin U. NCOA3 is a selective co-activator of estrogen receptor ?-mediated transactivation of PLAC1 in MCF-7 breast cancer cells. BMC Cancer. 2013;13:570 pubmed 出版商
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Tanaka T, Iino M. Knockdown of Sec8 promotes cell-cycle arrest at G1/S phase by inducing p21 via control of FOXO proteins. FEBS J. 2014;281:1068-84 pubmed 出版商
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Rubio N, Verrax J, Dewaele M, Verfaillie T, Johansen T, Piette J, et al. p38(MAPK)-regulated induction of p62 and NBR1 after photodynamic therapy promotes autophagic clearance of ubiquitin aggregates and reduces reactive oxygen species levels by supporting Nrf2-antioxidant signaling. Free Radic Biol Med. 2014;67:292-303 pubmed 出版商
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Han J, Rho S, Lee J, Bae J, Park S, Lee S, et al. Human cytomegalovirus (HCMV) US2 protein interacts with human CD1d (hCD1d) and down-regulates invariant NKT (iNKT) cell activity. Mol Cells. 2013;36:455-64 pubmed 出版商
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Singh A, Zapata M, Choi Y, Yoon S. GSI promotes vincristine-induced apoptosis by enhancing multi-polar spindle formation. Cell Cycle. 2014;13:157-66 pubmed 出版商
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Wu H, Balsbaugh J, Chandler H, Georgilis A, Zullow H, Shabanowitz J, et al. Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7. J Biol Chem. 2013;288:36398-408 pubmed 出版商
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Formosa A, Markert E, Lena A, Italiano D, Finazzi Agrò E, Levine A, et al. MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells. Oncogene. 2014;33:5173-82 pubmed 出版商
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Bana E, Sibille E, Valente S, Cerella C, Chaimbault P, Kirsch G, et al. A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death. Mol Carcinog. 2015;54:229-41 pubmed 出版商
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Gastaldello S, Chen X, Callegari S, Masucci M. Caspase-1 promotes Epstein-Barr virus replication by targeting the large tegument protein deneddylase to the nucleus of productively infected cells. PLoS Pathog. 2013;9:e1003664 pubmed 出版商
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Ni H, Du K, You M, Ding W. Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity. Am J Pathol. 2013;183:1815-1825 pubmed 出版商
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Soler A, Serra H, Pearce W, Angulo A, Guillermet Guibert J, Friedman L, et al. Inhibition of the p110? isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis. J Exp Med. 2013;210:1937-45 pubmed 出版商
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Fatemi S, Folsom T, Rooney R, Thuras P. Expression of GABAA ?2-, ?1- and ?-receptors are altered significantly in the lateral cerebellum of subjects with schizophrenia, major depression and bipolar disorder. Transl Psychiatry. 2013;3:e303 pubmed 出版商
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Yi X, Pashaj A, Xia M, Moreau R. Reversal of obesity-induced hypertriglyceridemia by (R)-?-lipoic acid in ZDF (fa/fa) rats. Biochem Biophys Res Commun. 2013;439:390-5 pubmed 出版商
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Subramanian V, Moorleghen J, Balakrishnan A, Howatt D, Chishti A, Uchida H. Calpain-2 compensation promotes angiotensin II-induced ascending and abdominal aortic aneurysms in calpain-1 deficient mice. PLoS ONE. 2013;8:e72214 pubmed 出版商
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O Brien M, Carbin S, Morrison J, Smith T. Decreased myometrial p160 ROCK-1 expression in obese women at term pregnancy. Reprod Biol Endocrinol. 2013;11:79 pubmed 出版商
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Garcia Jove Navarro M, Basset C, Arcondeguy T, Touriol C, Perez G, Prats H, et al. Api5 contributes to E2F1 control of the G1/S cell cycle phase transition. PLoS ONE. 2013;8:e71443 pubmed 出版商
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Gurung B, Feng Z, Hua X. Menin directly represses Gli1 expression independent of canonical Hedgehog signaling. Mol Cancer Res. 2013;11:1215-22 pubmed 出版商
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Wong K, Gascoyne D, Brown P, Soilleux E, Snell C, Chen H, et al. Reciprocal expression of the endocytic protein HIP1R and its repressor FOXP1 predicts outcome in R-CHOP-treated diffuse large B-cell lymphoma patients. Leukemia. 2014;28:362-72 pubmed 出版商
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Devi L, Ohno M. Mechanisms that lessen benefits of ?-secretase reduction in a mouse model of Alzheimer's disease. Transl Psychiatry. 2013;3:e284 pubmed 出版商
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Montiel V, León Gómez E, Bouzin C, Esfahani H, Romero Pérez M, Lobysheva I, et al. Genetic deletion of aquaporin-1 results in microcardia and low blood pressure in mouse with intact nitric oxide-dependent relaxation, but enhanced prostanoids-dependent relaxation. Pflugers Arch. 2014;466:237-51 pubmed 出版商
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Hou P, Chuang C, Kao C, Chou S, Stone L, Ho H, et al. LHX2 regulates the neural differentiation of human embryonic stem cells via transcriptional modulation of PAX6 and CER1. Nucleic Acids Res. 2013;41:7753-70 pubmed 出版商
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Fatemi S, Folsom T, Rooney R, Thuras P. mRNA and protein expression for novel GABAA receptors ? and ?2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway. Transl Psychiatry. 2013;3:e271 pubmed 出版商
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Rajendran P, Kidane A, Yu T, Dashwood W, Bisson W, LOHR C, et al. HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates. Epigenetics. 2013;8:612-23 pubmed 出版商
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Zhang X, Hernandez I, Rei D, Mair W, Laha J, Cornwell M, et al. Diaminothiazoles modify Tau phosphorylation and improve the tauopathy in mouse models. J Biol Chem. 2013;288:22042-56 pubmed 出版商
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Gillette M, Bray K, Blumenthaler A, Vargo Gogola T. P190B RhoGAP overexpression in the developing mammary epithelium induces TGF?-dependent fibroblast activation. PLoS ONE. 2013;8:e65105 pubmed 出版商
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Huang B, Ray P, Iwasaki K, Tsuji Y. Transcriptional regulation of the human ferritin gene by coordinated regulation of Nrf2 and protein arginine methyltransferases PRMT1 and PRMT4. FASEB J. 2013;27:3763-74 pubmed 出版商
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Mobasher M, Gonzalez Rodriguez A, Santamaria B, Ramos S, Martin M, Goya L, et al. Protein tyrosine phosphatase 1B modulates GSK3?/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity. Cell Death Dis. 2013;4:e626 pubmed 出版商
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Sharma A, Diecke S, Zhang W, Lan F, He C, Mordwinkin N, et al. The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. J Biol Chem. 2013;288:18439-47 pubmed 出版商
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Nguyen H, Hübener J, Weber J, Grueninger S, Riess O, Weiss A. Cerebellar soluble mutant ataxin-3 level decreases during disease progression in Spinocerebellar Ataxia Type 3 mice. PLoS ONE. 2013;8:e62043 pubmed 出版商
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Park Y, Ko J, Jang Y, Kwon Y. Activation of AMP-activated protein kinase alleviates homocysteine-mediated neurotoxicity in SH-SY5Y cells. Neurochem Res. 2013;38:1561-71 pubmed 出版商
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Moreno A, Soleto I, García Sanz P, Moreno Bueno G, Palmero I. ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth. Oncogene. 2014;33:1945-53 pubmed 出版商
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Rodriguez Martin T, Cuchillo Ibanez I, Noble W, Nyenya F, Anderton B, Hanger D. Tau phosphorylation affects its axonal transport and degradation. Neurobiol Aging. 2013;34:2146-57 pubmed 出版商
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Mandemakers W, Abuhatzira L, Xu H, Caromile L, Hébert S, Snellinx A, et al. Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2 ?: identification of miR-153 target genes with functions related to IA-2? in pancreas and brain. Diabetologia. 2013;56:1547-56 pubmed 出版商
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Ipenberg I, Guttmann Raviv N, Khoury H, Kupershmit I, Ayoub N. Heat shock protein 90 (Hsp90) selectively regulates the stability of KDM4B/JMJD2B histone demethylase. J Biol Chem. 2013;288:14681-7 pubmed 出版商
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Vanoirbeek E, Eelen G, Verlinden L, Carmeliet G, Mathieu C, Bouillon R, et al. PDLIM2 expression is driven by vitamin D and is involved in the pro-adhesion, and anti-migration and -invasion activity of vitamin D. Oncogene. 2014;33:1904-11 pubmed 出版商
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Ward J, Rider V, Abdou N, Kimler B. Estradiol differentially regulates calreticulin: a potential link with abnormal T cell function in systemic lupus erythematosus?. Lupus. 2013;22:583-96 pubmed 出版商
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Mitterberger M, Zwerschke W. Mechanisms of resveratrol-induced inhibition of clonal expansion and terminal adipogenic differentiation in 3T3-L1 preadipocytes. J Gerontol A Biol Sci Med Sci. 2013;68:1356-76 pubmed 出版商
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Dellago H, Preschitz Kammerhofer B, Terlecki Zaniewicz L, Schreiner C, Fortschegger K, Chang M, et al. High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan. Aging Cell. 2013;12:446-58 pubmed 出版商
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Yamada H, Abe T, Satoh A, Okazaki N, Tago S, Kobayashi K, et al. Stabilization of actin bundles by a dynamin 1/cortactin ring complex is necessary for growth cone filopodia. J Neurosci. 2013;33:4514-26 pubmed 出版商
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Werwein E, Dzuganova M, Usadel C, Klempnauer K. B-Myb switches from Cyclin/Cdk-dependent to Jnk- and p38 kinase-dependent phosphorylation and associates with SC35 bodies after UV stress. Cell Death Dis. 2013;4:e511 pubmed 出版商
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Petrie C, Smithson L, Crotty A, Michalski B, Fahnestock M, Kawaja M. Overexpression of nerve growth factor by murine smooth muscle cells: role of the p75 neurotrophin receptor on sympathetic and sensory sprouting. J Comp Neurol. 2013;521:2621-43 pubmed 出版商
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Ogiwara H, Kohno T. CBP and p300 histone acetyltransferases contribute to homologous recombination by transcriptionally activating the BRCA1 and RAD51 genes. PLoS ONE. 2012;7:e52810 pubmed 出版商
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Landry W, Woolley J, Cotter T. Imatinib and Nilotinib inhibit Bcr-Abl-induced ROS through targeted degradation of the NADPH oxidase subunit p22phox. Leuk Res. 2013;37:183-9 pubmed 出版商
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产品信息
Product No. :
A5441
产品名称 :
Monoclonal Anti-β-Actin antibody produced in mouse
宿主 :
小鼠
共轭标签 :
未共轭
抗体类型 :
单克隆
Clone Number (if monoclonal) :
AC-15
应用/描述 :
Suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections); western blot: 1:5,000-1:10,000 using cultured human or chicken fibroblast cell extracts; indirect immunofluorescence: 1:1,000-1:2,000 using cultured human or chicken fibroblasts
物种活性 :
Dictyostelium discoideum guinea pig, canine, Hirudo medicinalis, feline, pig, carp, mouse, chicken, rabbit, sheep, rat, human, bovine
抗体亚型 :
IgG1
储存 :
存放在-20°C
更多信息或购买 :
公司信息
西格玛奥德里奇
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