产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
FLUKA, Sigma-Aldrich, Roche Applied Science
产品类型 :
抗体
产品名称 :
单克隆抗抗肌萎缩蛋白在小鼠生产的抗体
目录 :
D8168
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
MANDYS8
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 45
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 图 2
  • 免疫印迹; 小鼠; 图 3a
Zhang Y, Li H, Min Y, Sanchez Ortiz E, Huang J, Mireault A, et al. Enhanced CRISPR-Cas9 correction of Duchenne muscular dystrophy in mice by a self-complementary AAV delivery system. Sci Adv. 2020;6:eaay6812 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4b
Min Y, Li H, Rodriguez Caycedo C, Mireault A, Huang J, Shelton J, et al. CRISPR-Cas9 corrects Duchenne muscular dystrophy exon 44 deletion mutations in mice and human cells. Sci Adv. 2019;5:eaav4324 pubmed 出版商
  • 免疫组化; 人类; 1:800; 图 3a
  • 免疫印迹; 人类; 图 3d
Long C, Li H, Tiburcy M, Rodriguez Caycedo C, Kyrychenko V, Zhou H, et al. Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing. Sci Adv. 2018;4:eaap9004 pubmed 出版商
  • 免疫组化; 小鼠; 1:400; 图 s8
Park S, Yun Y, Lim J, Kim M, Kim S, Kim J, et al. Stabilin-2 modulates the efficiency of myoblast fusion during myogenic differentiation and muscle regeneration. Nat Commun. 2016;7:10871 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:400; 图 3
Strauss J, Shaw C, Bradley H, Wilson O, Dorval T, Pilling J, et al. Immunofluorescence microscopy of SNAP23 in human skeletal muscle reveals colocalization with plasma membrane, lipid droplets, and mitochondria. Physiol Rep. 2016;4: pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 s20a
Nelson C, Hakim C, Ousterout D, Thakore P, Moreb E, Castellanos Rivera R, et al. In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy. Science. 2016;351:403-7 pubmed 出版商
  • 免疫组化; 小鼠; 图 s4a, s13b
  • 免疫印迹; 小鼠; 1:1000; 图 s8a, s8c, s13c
Long C, Amoasii L, Mireault A, McAnally J, Li H, Sanchez Ortiz E, et al. Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy. Science. 2016;351:400-3 pubmed 出版商
  • 免疫组化-冰冻切片; 人类
Molsted S, Andersen J, Harrison A, Eidemak I, Mackey A. Fiber type-specific response of skeletal muscle satellite cells to high-intensity resistance training in dialysis patients. Muscle Nerve. 2015;52:736-45 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 1:1000; 图 5D
Ousterout D, Kabadi A, Thakore P, Majoros W, Reddy T, Gersbach C. Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy. Nat Commun. 2015;6:6244 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Ousterout D, Kabadi A, Thakore P, Perez Pinera P, Brown M, Majoros W, et al. Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases. Mol Ther. 2015;23:523-32 pubmed 出版商
  • 免疫组化; 小鼠; 1:100
Gouspillou G, Sgarioto N, Norris B, Barbat Artigas S, Aubertin Leheudre M, Morais J, et al. The relationship between muscle fiber type-specific PGC-1α content and mitochondrial content varies between rodent models and humans. PLoS ONE. 2014;9:e103044 pubmed 出版商
Amoasii L, Li H, Zhang Y, Min Y, Sanchez Ortiz E, Shelton J, et al. In vivo non-invasive monitoring of dystrophin correction in a new Duchenne muscular dystrophy reporter mouse. Nat Commun. 2019;10:4537 pubmed 出版商
Elia A, Wilson O, Lees M, Parker P, Barlow M, Cocks M, et al. Skeletal muscle, haematological and splenic volume characteristics of elite breath-hold divers. Eur J Appl Physiol. 2019;119:2499-2511 pubmed 出版商
Soendenbroe C, Heisterberg M, Schjerling P, Karlsen A, Kjaer M, Andersen J, et al. Molecular indicators of denervation in aging human skeletal muscle. Muscle Nerve. 2019;60:453-463 pubmed 出版商
Ito A, Ohnuki Y, Suita K, Ishikawa M, Mototani Y, Shiozawa K, et al. Role of β-adrenergic signaling in masseter muscle. PLoS ONE. 2019;14:e0215539 pubmed 出版商
Nelson C, Wu Y, Gemberling M, Oliver M, Waller M, Bohning J, et al. Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy. Nat Med. 2019;25:427-432 pubmed 出版商
Leduc Gaudet J, Reynaud O, Hussain S, Gouspillou G. Parkin overexpression protects from ageing-related loss of muscle mass and strength. J Physiol. 2019;597:1975-1991 pubmed 出版商
Yuan J, Ma Y, Huang T, Chen Y, Peng Y, Li B, et al. Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase. Mol Cell. 2018;72:380-394.e7 pubmed 出版商
Wang D, Mokhonova E, Kendall G, Becerra D, Naeini Y, Cantor R, et al. Repurposing Dantrolene for Long-Term Combination Therapy to Potentiate Antisense-Mediated DMD Exon Skipping in the mdx Mouse. Mol Ther Nucleic Acids. 2018;11:180-191 pubmed 出版商
Morano M, Ronchi G, Nicolò V, Fornasari B, Crosio A, Perroteau I, et al. Modulation of the Neuregulin 1/ErbB system after skeletal muscle denervation and reinnervation. Sci Rep. 2018;8:5047 pubmed 出版商
Ugwu F, Yu A, Sin T, Tam B, Lai C, Wong S, et al. Protective Effect of Unacylated Ghrelin on Compression-Induced Skeletal Muscle Injury Mediated by SIRT1-Signaling. Front Physiol. 2017;8:962 pubmed 出版商
Mackey A, Kjaer M. The breaking and making of healthy adult human skeletal muscle in vivo. Skelet Muscle. 2017;7:24 pubmed 出版商
Kyrychenko V, Kyrychenko S, Tiburcy M, Shelton J, Long C, Schneider J, et al. Functional correction of dystrophin actin binding domain mutations by genome editing. JCI Insight. 2017;2: pubmed 出版商
Zhang Y, Long C, Li H, McAnally J, Baskin K, Shelton J, et al. CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice. Sci Adv. 2017;3:e1602814 pubmed 出版商
Fuoco C, Rizzi R, Biondo A, Longa E, Mascaro A, Shapira Schweitzer K, et al. In vivo generation of a mature and functional artificial skeletal muscle. EMBO Mol Med. 2015;7:411-22 pubmed 出版商
Chaudhuri O, Gu L, Darnell M, Klumpers D, Bencherif S, Weaver J, et al. Substrate stress relaxation regulates cell spreading. Nat Commun. 2015;6:6364 pubmed 出版商
Kayman Kurekci G, Talim B, Korkusuz P, Sayar N, Sarioglu T, Oncel I, et al. Mutation in TOR1AIP1 encoding LAP1B in a form of muscular dystrophy: a novel gene related to nuclear envelopathies. Neuromuscul Disord. 2014;24:624-33 pubmed 出版商
Buchholz B, Perez V, Siachoque N, Miksztowicz V, Berg G, Rodriguez M, et al. Dystrophin proteolysis: a potential target for MMP-2 and its prevention by ischemic preconditioning. Am J Physiol Heart Circ Physiol. 2014;307:H88-96 pubmed 出版商
Gouspillou G, Sgarioto N, Kapchinsky S, Purves Smith F, Norris B, Pion C, et al. Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans. FASEB J. 2014;28:1621-33 pubmed 出版商
Hollinger K, Yang C, Montz R, Nonneman D, Ross J, Selsby J. Dystrophin insufficiency causes selective muscle histopathology and loss of dystrophin-glycoprotein complex assembly in pig skeletal muscle. FASEB J. 2014;28:1600-9 pubmed 出版商
Matsakas A, Yadav V, Lorca S, Narkar V. Muscle ERR? mitigates Duchenne muscular dystrophy via metabolic and angiogenic reprogramming. FASEB J. 2013;27:4004-16 pubmed 出版商
Rougier J, Gavillet B, Abriel H. Proteasome inhibitor (MG132) rescues Nav1.5 protein content and the cardiac sodium current in dystrophin-deficient mdx (5cv) mice. Front Physiol. 2013;4:51 pubmed 出版商
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Teng B, Tam E, Benzie I, Siu P. Protective effect of caspase inhibition on compression-induced muscle damage. J Physiol. 2011;589:3349-69 pubmed 出版商
Kielbasa O, Reynolds J, Wu C, Snyder C, Cho M, Weiler H, et al. Myospryn is a calcineurin-interacting protein that negatively modulates slow-fiber-type transformation and skeletal muscle regeneration. FASEB J. 2011;25:2276-86 pubmed 出版商
Thomas M, Khan W, Betik A, Wright K, Hepple R. Initiating exercise training in late middle age minimally protects muscle contractile function and increases myocyte oxidative damage in senescent rats. Exp Gerontol. 2010;45:856-67 pubmed 出版商
Zanoteli E, van de Vlekkert D, Bonten E, Hu H, Mann L, Gomero E, et al. Muscle degeneration in neuraminidase 1-deficient mice results from infiltration of the muscle fibers by expanded connective tissue. Biochim Biophys Acta. 2010;1802:659-72 pubmed 出版商
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Oishi Y, Hayashida M, Tsukiashi S, Taniguchi K, Kami K, Roy R, et al. Heat stress increases myonuclear number and fiber size via satellite cell activation in rat regenerating soleus fibers. J Appl Physiol (1985). 2009;107:1612-21 pubmed 出版商
Blitzblau R, Storer E, Jacob M. Dystrophin and utrophin isoforms are expressed in glia, but not neurons, of the avian parasympathetic ciliary ganglion. Brain Res. 2008;1218:21-34 pubmed 出版商
Jansen K, Pavlath G. Mannose receptor regulates myoblast motility and muscle growth. J Cell Biol. 2006;174:403-13 pubmed
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Horsley V, Friday B, Matteson S, Kegley K, Gephart J, Pavlath G. Regulation of the growth of multinucleated muscle cells by an NFATC2-dependent pathway. J Cell Biol. 2001;153:329-38 pubmed
Sedgwick S, Nguyen T, Ellis J, Crowne H, Morris G. Rapid mapping by transposon mutagenesis of epitopes on the muscular dystrophy protein, dystrophin. Nucleic Acids Res. 1991;19:5889-94 pubmed
Nguyen thi Man -, Cartwright A, Morris G, Love D, Bloomfield J, Davies K. Monoclonal antibodies against defined regions of the muscular dystrophy protein, dystrophin. FEBS Lett. 1990;262:237-40 pubmed
产品信息
目录代码 :
D8168
产品名称 :
单克隆抗抗肌萎缩蛋白在小鼠生产的抗体
产品类型 :
ANTIBODIES - SIAL
Product Group :
蛋白&通路技术
宿主物种 :
小鼠
克隆性 :
单克隆
共轭 :
未共轭
克隆名称 :
MANDYS8
抗体亚型 :
IgG2b
产品描述 :
clone MANDYS8, ascites fluid
更多信息或购买 :
公司信息
西格玛奥德里奇
上海市徐汇区淮海中路1010号嘉华中心41楼
techservCN@sial.com
http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
公司总部: 美国
Sigma-Aldrich是一家在生命科学领域领先的且拥有高科技产品的公司,致力于为生命科学、制药化工等领域提供高质量的服务和产品。