Katoh I, Maehata Y, Moriishi K, Hata R, Kurata S. C-terminal α Domain of p63 Binds to p300 to Coactivate β-Catenin. Neoplasia. 2019;21:494-503 pubmed 出版商

van Welsem T, Korthout T, Ekkebus R, Morais D, Molenaar T, van Harten K, et al. Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism. Nucleic Acids Res. 2018;46:11251-11261 pubmed 出版商

Turkington H, Juozapaitis M, Tsolakos N, Corrales Aguilar E, Schwemmle M, Hale B. Unexpected Functional Divergence of Bat Influenza Virus NS1 Proteins. J Virol. 2018;92: pubmed 出版商

Lamonica J, Kwon D, Goffin D, Fenik P, Johnson B, Cui Y, et al. Elevating expression of MeCP2 T158M rescues DNA binding and Rett syndrome-like phenotypes. J Clin Invest. 2017;127:1889-1904 pubmed 出版商

Wheaton K, Sarkari F, Stanly Johns B, Davarinejad H, Egorova O, Kaustov L, et al. UbE2E1/UBCH6 Is a Critical in Vivo E2 for the PRC1-catalyzed Ubiquitination of H2A at Lys-119. J Biol Chem. 2017;292:2893-2902 pubmed 出版商

Liang J, Cao R, Zhang Y, Xia Y, Zheng Y, Li X, et al. PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis. Nat Commun. 2016;7:12431 pubmed 出版商

Hayashi S, Akiyama R, Wong J, Tahara N, Kawakami H, Kawakami Y. Gata6-Dependent GLI3 Repressor Function is Essential in Anterior Limb Progenitor Cells for Proper Limb Development. PLoS Genet. 2016;12:e1006138 pubmed 出版商

Glenewinkel F, Cohen M, King C, Kaspar S, Bamberg Lemper S, Mymryk J, et al. The adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2. Sci Rep. 2016;6:28241 pubmed 出版商

Wang Y, Li Y, Hu G, Huang X, Rao H, Xiong X, et al. Nek2A phosphorylates and stabilizes SuFu: A new strategy of Gli2/Hedgehog signaling regulatory mechanism. Cell Signal. 2016;28:1304-13 pubmed 出版商

Eichner R, Heider M, Fernández Sáiz V, van Bebber F, Garz A, Lemeer S, et al. Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity. Nat Med. 2016;22:735-43 pubmed 出版商

Li K, Yu R, Fan L, Wei N, Chen H, Deng X. DELLA-mediated PIF degradation contributes to coordination of light and gibberellin signalling in Arabidopsis. Nat Commun. 2016;7:11868 pubmed 出版商

Jing M, Guo B, Li H, Yang B, Wang H, Kong G, et al. A Phytophthora sojae effector suppresses endoplasmic reticulum stress-mediated immunity by stabilizing plant Binding immunoglobulin Proteins. Nat Commun. 2016;7:11685 pubmed 出版商

Speer S, Li Z, Buta S, Payelle Brogard B, Qian L, Vigant F, et al. ISG15 deficiency and increased viral resistance in humans but not mice. Nat Commun. 2016;7:11496 pubmed 出版商

Aizawa S, Okamoto T, Sugiyama Y, Kouwaki T, Ito A, Suzuki T, et al. TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis. Nat Commun. 2016;7:11379 pubmed 出版商

Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun. 2016;7:11127 pubmed 出版商

Douanne T, Gavard J, Bidère N. The paracaspase MALT1 cleaves the LUBAC subunit HOIL1 during antigen receptor signaling. J Cell Sci. 2016;129:1775-80 pubmed 出版商

Chavali P, Chandrasekaran G, Barr A, Tátrai P, Taylor C, Papachristou E, et al. A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer. Nat Commun. 2016;7:11005 pubmed 出版商

Persaud S, Park S, Ishigami Yuasa M, Koyano Nakagawa N, Kagechika H, Wei L. All trans-retinoic acid analogs promote cancer cell apoptosis through non-genomic Crabp1 mediating ERK1/2 phosphorylation. Sci Rep. 2016;6:22396 pubmed 出版商

Oswald F, Rodriguez P, Giaimo B, Antonello Z, Mira L, Mittler G, et al. A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes. Nucleic Acids Res. 2016;44:4703-20 pubmed 出版商

Liu L, Liu X, Ren X, Tian Y, Chen Z, Xu X, et al. Smad2 and Smad3 have differential sensitivity in relaying TGFβ signaling and inversely regulate early lineage specification. Sci Rep. 2016;6:21602 pubmed 出版商

Castaño J, Morera C, Sesé B, Boue S, Bonet Costa C, Marti M, et al. SETD7 Regulates the Differentiation of Human Embryonic Stem Cells. PLoS ONE. 2016;11:e0149502 pubmed 出版商

Baietti M, Simíček M, Abbasi Asbagh L, Radaelli E, Lievens S, Crowther J, et al. OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination. EMBO Mol Med. 2016;8:288-303 pubmed 出版商

Wike C, Graves H, Hawkins R, Gibson M, Ferdinand M, Zhang T, et al. Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis. elife. 2016;5:e11402 pubmed 出版商

Kim J, He X, Orr B, Wutz G, Hill V, Peters J, et al. Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2. PLoS Genet. 2016;12:e1005865 pubmed 出版商

Chen S, Blank M, Iyer A, Huang B, Wang L, Grummt I, et al. SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing. Nat Commun. 2016;7:10734 pubmed 出版商

White Y, Bagchi A, Van Ziffle J, Inguva A, Bollag G, Zhang C, et al. KRAS insertion mutations are oncogenic and exhibit distinct functional properties. Nat Commun. 2016;7:10647 pubmed 出版商

Brown M, Kim Y, Williams G, Huck J, Surtees J, Finkelstein I. Dynamic DNA binding licenses a repair factor to bypass roadblocks in search of DNA lesions. Nat Commun. 2016;7:10607 pubmed 出版商

Podmirseg S, Jäkel H, Ranches G, Kullmann M, Sohm B, Villunger A, et al. Caspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasion. Oncogene. 2016;35:4580-90 pubmed 出版商

de Dieuleveult M, Yen K, Hmitou I, Depaux A, Boussouar F, Bou Dargham D, et al. Genome-wide nucleosome specificity and function of chromatin remodellers in ES cells. Nature. 2016;530:113-6 pubmed 出版商

Couderc C, Boin A, Fuhrmann L, Vincent Salomon A, Mandati V, Kieffer Y, et al. AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by Merlin. Neoplasia. 2016;18:10-24 pubmed 出版商

Wang Z, Huang M, Ma X, Li H, Tang T, Guo C. REV1 promotes PCNA monoubiquitylation through interacting with ubiquitylated RAD18. J Cell Sci. 2016;129:1223-33 pubmed 出版商

Luchsinger L, de Almeida M, Corrigan D, Mumau M, Snoeck H. Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential. Nature. 2016;529:528-31 pubmed 出版商

Lechtenberg B, Rajput A, Sanishvili R, Dobaczewska M, Ware C, Mace P, et al. Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation. Nature. 2016;529:546-50 pubmed 出版商

Chavoshi S, Egorova O, Lacdao I, Farhadi S, Sheng Y, Saridakis V. Identification of Kaposi Sarcoma Herpesvirus (KSHV) vIRF1 Protein as a Novel Interaction Partner of Human Deubiquitinase USP7. J Biol Chem. 2016;291:6281-91 pubmed 出版商

Soo Lee N, Jin Chung H, Kim H, Yun Lee S, Ji J, Seo Y, et al. TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage. Nat Commun. 2016;7:10463 pubmed 出版商

Du Y, Yamaguchi H, Wei Y, Hsu J, Wang H, Hsu Y, et al. Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors. Nat Med. 2016;22:194-201 pubmed 出版商

Kibe T, Zimmermann M, de Lange T. TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres. Mol Cell. 2016;61:236-46 pubmed 出版商

Singh H, Li M, Hall L, Chen S, Sukur S, Lu R, et al. MaxiK channel interactome reveals its interaction with GABA transporter 3 and heat shock protein 60 in the mammalian brain. Neuroscience. 2016;317:76-107 pubmed 出版商

Kuo C, Li X, Stark J, Shih H, Ann D. RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner. Cell Cycle. 2016;15:787-98 pubmed 出版商

Zhang Q, Wan M, Shi J, Horita D, Miller L, Kute T, et al. Yin Yang 1 promotes mTORC2-mediated AKT phosphorylation. J Mol Cell Biol. 2016;8:232-43 pubmed 出版商

Yamamoto H, Ramos Molina B, Lick A, Prideaux M, Albornoz V, Bonewald L, et al. Posttranslational processing of FGF23 in osteocytes during the osteoblast to osteocyte transition. Bone. 2016;84:120-130 pubmed 出版商

Carroll B, Maetzel D, Maddocks O, Otten G, Ratcliff M, Smith G, et al. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity. elife. 2016;5: pubmed 出版商

Wang M, Itoh M, Li S, Hida Y, Ohta K, Hayakawa M, et al. CED-4 is an mRNA-binding protein that delivers ced-3 mRNA to ribosomes. Biochem Biophys Res Commun. 2016;470:48-53 pubmed 出版商

Yasuma K, Yasunaga J, Takemoto K, Sugata K, Mitobe Y, Takenouchi N, et al. HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT). PLoS Pathog. 2016;12:e1005372 pubmed 出版商

Wilhelm K, Happel K, Eelen G, Schoors S, Oellerich M, Lim R, et al. FOXO1 couples metabolic activity and growth state in the vascular endothelium. Nature. 2016;529:216-20 pubmed 出版商

Huang P, Chan P, Su P, Chen L, Li H. Chloroplast Hsp93 Directly Binds to Transit Peptides at an Early Stage of the Preprotein Import Process. Plant Physiol. 2016;170:857-66 pubmed 出版商

Lagarrigue S, Lopez Mejia I, Denechaud P, Escoté X, Castillo Armengol J, Jimenez V, et al. CDK4 is an essential insulin effector in adipocytes. J Clin Invest. 2016;126:335-48 pubmed 出版商

Kim J, Lee K, Rhee K. PLK1 regulation of PCNT cleavage ensures fidelity of centriole separation during mitotic exit. Nat Commun. 2015;6:10076 pubmed 出版商

Shi H, Wang Y, Li X, Zhan X, Tang M, Fina M, et al. NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component. Nat Immunol. 2016;17:250-8 pubmed 出版商

Ulbrich L, Favaloro F, Trobiani L, Marchetti V, Patel V, Pascucci T, et al. Autism-associated R451C mutation in neuroligin3 leads to activation of the unfolded protein response in a PC12 Tet-On inducible system. Biochem J. 2016;473:423-34 pubmed 出版商

Song H, Tao L, Chen C, Pan L, Hao J, Ni Y, et al. USP17-mediated deubiquitination and stabilization of HDAC2 in cigarette smoke extract-induced inflammation. Int J Clin Exp Pathol. 2015;8:10707-15 pubmed

Debruyne D, Bhatnagar N, Sharma B, Luther W, Moore N, Cheung N, et al. ALK inhibitor resistance in ALK(F1174L)-driven neuroblastoma is associated with AXL activation and induction of EMT. Oncogene. 2016;35:3681-91 pubmed 出版商

Wu Y, Wang L, Bao H, Zou S, Fu C, Gong H, et al. Nrdp1S, short variant of Nrdp1, inhibits human glioma progression by increasing Nrdp1-mediated ErbB3 ubiquitination and degradation. J Cell Mol Med. 2016;20:422-9 pubmed 出版商

Chen X, Ji Z, Webber A, Sharrocks A. Genome-wide binding studies reveal DNA binding specificity mechanisms and functional interplay amongst Forkhead transcription factors. Nucleic Acids Res. 2016;44:1566-78 pubmed 出版商

Ozgur S, Basquin J, Kamenska A, Filipowicz W, Standart N, Conti E. Structure of a Human 4E-T/DDX6/CNOT1 Complex Reveals the Different Interplay of DDX6-Binding Proteins with the CCR4-NOT Complex. Cell Rep. 2015;13:703-711 pubmed 出版商

Han Y, Kim D, Na T, Ka N, Choi H, Lee M. RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure. Nucleic Acids Res. 2016;44:1095-104 pubmed 出版商

Young L, Marzio A, Pérez Durán P, Reid D, Meredith D, Roberti D, et al. TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage Response. Cell Rep. 2015;13:451-459 pubmed 出版商

Sun S, Reddy B, Irvine K. Localization of Hippo signalling complexes and Warts activation in vivo. Nat Commun. 2015;6:8402 pubmed 出版商

Guo Y, Feng W, Sy S, Huen M. ATM-dependent Phosphorylation of the Fanconi Anemia Protein PALB2 Promotes the DNA Damage Response. J Biol Chem. 2015;290:27545-56 pubmed 出版商

Rao X, Duan X, Mao W, Li X, Li Z, Li Q, et al. O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth. Nat Commun. 2015;6:8468 pubmed 出版商

Anderson K, Russell A, Foletta V. NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity. FEBS Open Bio. 2015;5:668-81 pubmed 出版商

Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, et al. The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. PLoS Genet. 2015;11:e1005503 pubmed 出版商

Bender J, Engeholm M, Ederer M, Breu J, Møller T, Michalakis S, et al. Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif. PLoS ONE. 2015;10:e0136768 pubmed 出版商

Yang F, Yu X, Liu C, Qu C, Gong Z, Liu H, et al. Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR. Nat Commun. 2015;6:8202 pubmed 出版商

Zhang J, Tripathi D, Jing J, Alexander A, Kim J, Powell R, et al. ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol. 2015;17:1259-1269 pubmed 出版商

Lee Y, Min C, Kim T, Song H, Lim Y, Kim D, et al. Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter. EMBO Rep. 2015;16:1318-33 pubmed 出版商

Yao X, Tang Z, Fu X, Yin J, Liang Y, Li C, et al. The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination. EMBO J. 2015;34:2885-902 pubmed 出版商

Jing J, He L, Sun A, Quintana A, Ding Y, Ma G, et al. Proteomic mapping of ER-PM junctions identifies STIMATE as a regulator of Ca²⁺ influx. Nat Cell Biol. 2015;17:1339-47 pubmed 出版商

Xu D, Wang Z, Zhang Y, Jiang W, Pan Y, Song B, et al. PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus. Nat Commun. 2015;6:8100 pubmed 出版商

Yu C, Ji S, Sha Q, Sun Q, Fan H. CRL4-DCAF1 ubiquitin E3 ligase directs protein phosphatase 2A degradation to control oocyte meiotic maturation. Nat Commun. 2015;6:8017 pubmed 出版商

Li M, Zhou L, Lam H. Paraformaldehyde Fixation May Lead to Misinterpretation of the Subcellular Localization of Plant High Mobility Group Box Proteins. PLoS ONE. 2015;10:e0135033 pubmed 出版商

Steingruber M, Socher E, Hutterer C, Webel R, Bergbrede T, Lenac T, et al. The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain. Viruses. 2015;7:4582-601 pubmed 出版商

Takata K, Tomida J, Reh S, Swanhart L, Takata M, Hukriede N, et al. Conserved overlapping gene arrangement, restricted expression, and biochemical activities of DNA polymerase ν (POLN). J Biol Chem. 2015;290:24278-93 pubmed 出版商

Thandapani P, Song J, Gandin V, Cai Y, Rouleau S, Garant J, et al. Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes. elife. 2015;4: pubmed 出版商

Zhen Y, Li W. Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33A(D251E) mutation. Autophagy. 2015;11:1608-22 pubmed 出版商

He S, Zhao Z, Yang Y, O Connell D, Zhang X, Oh S, et al. Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers. Nat Commun. 2015;6:7839 pubmed 出版商

Lee C, Yang Y, Chen C, Liu J. Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell death. Oncogene. 2016;35:1988-95 pubmed 出版商

Gentili C, Castor D, Kaden S, Lauterbach D, Gysi M, Steigemann P, et al. Chromosome Missegregation Associated with RUVBL1 Deficiency. PLoS ONE. 2015;10:e0133576 pubmed 出版商

Bollimpelli V, Kondapi A. Enriched rat primary ventral mesencephalic neurons as an in-vitro culture model. Neuroreport. 2015;26:728-34 pubmed 出版商

Pedros C, Gaud G, Bernard I, Kassem S, Chabod M, Lagrange D, et al. An Epistatic Interaction between Themis1 and Vav1 Modulates Regulatory T Cell Function and Inflammatory Bowel Disease Development. J Immunol. 2015;195:1608-16 pubmed 出版商

Xu Q, Zhang Y, Wei Q, Huang Y, Li Y, Ling K, et al. BBS4 and BBS5 show functional redundancy in the BBSome to regulate the degradative sorting of ciliary sensory receptors. Sci Rep. 2015;5:11855 pubmed 出版商

Blanchette C, Perrat P, Thackeray A, Benard C. Glypican Is a Modulator of Netrin-Mediated Axon Guidance. PLoS Biol. 2015;13:e1002183 pubmed 出版商

Loveless T, Topacio B, Vashisht A, Galaang S, Ulrich K, Young B, et al. DNA Damage Regulates Translation through β-TRCP Targeting of CReP. PLoS Genet. 2015;11:e1005292 pubmed 出版商

Tindi J, Chávez A, Cvejic S, Calvo Ochoa E, Castillo P, Jordan B. ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by Regulating GluN2B Subunit Localization. J Neurosci. 2015;35:8986-96 pubmed 出版商

Song H, Pu J, Wang L, Wu L, Xiao J, Liu Q, et al. ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation. Autophagy. 2015;11:1308-25 pubmed 出版商

Omori Y, Chaya T, Yoshida S, Irie S, Tsujii T, Furukawa T. Identification of G Protein-Coupled Receptors (GPCRs) in Primary Cilia and Their Possible Involvement in Body Weight Control. PLoS ONE. 2015;10:e0128422 pubmed 出版商

Nicolai S, Filippi S, Caputo M, Cipak L, Gregan J, Ammerer G, et al. Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics. PLoS ONE. 2015;10:e0128558 pubmed 出版商

Lu H, Li Z, Zhang W, Schulze Gahmen U, Xue Y, Zhou Q. Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription. Nucleic Acids Res. 2015;43:5868-79 pubmed 出版商

Zhao Z, Sagare A, Ma Q, Halliday M, Kong P, Kisler K, et al. Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance. Nat Neurosci. 2015;18:978-87 pubmed 出版商

Jackson B, Ivanova I, Dagnino L. An ELMO2-RhoG-ILK network modulates microtubule dynamics. Mol Biol Cell. 2015;26:2712-25 pubmed 出版商

Iglesias Bartolomé R, Torres D, Marone R, Feng X, Martin D, Simaan M, et al. Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis. Nat Cell Biol. 2015;17:793-803 pubmed 出版商

Ibsen M, Gad H, Andersen L, Hornung V, Julkunen I, Sarkar S, et al. Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling. Nucleic Acids Res. 2015;43:5236-48 pubmed 出版商

Park J, Zhao L, Willingham M, Cheng S. Oncogenic mutations of thyroid hormone receptor β. Oncotarget. 2015;6:8115-31 pubmed

Cattoglio C, Zhang E, Grubisic I, Chiba K, Fong Y, Tjian R. Functional and mechanistic studies of XPC DNA-repair complex as transcriptional coactivator in embryonic stem cells. Proc Natl Acad Sci U S A. 2015;112:E2317-26 pubmed 出版商

González Prieto R, Cuijpers S, Kumar R, Hendriks I, Vertegaal A. c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4. Cell Cycle. 2015;14:1859-72 pubmed 出版商

Mondal A, Potts G, Dawson A, Coon J, Mehle A. Phosphorylation at the homotypic interface regulates nucleoprotein oligomerization and assembly of the influenza virus replication machinery. PLoS Pathog. 2015;11:e1004826 pubmed 出版商

Alexander J, Hota S, He D, Thomas S, Ho L, Pennacchio L, et al. Brg1 modulates enhancer activation in mesoderm lineage commitment. Development. 2015;142:1418-30 pubmed 出版商

Freischmidt A, Wieland T, Richter B, Ruf W, Schaeffer V, Müller K, et al. Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia. Nat Neurosci. 2015;18:631-6 pubmed 出版商

Kobayashi A, Hashizume C, Dowaki T, Wong R. Therapeutic potential of mitotic interaction between the nucleoporin Tpr and aurora kinase A. Cell Cycle. 2015;14:1447-58 pubmed 出版商

Hendriks I, Treffers L, Verlaan de Vries M, Olsen J, Vertegaal A. SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage. Cell Rep. 2015;10:1778-1791 pubmed 出版商

Xing M, Yang M, Huo W, Feng F, Wei L, Jiang W, et al. Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway. Nat Commun. 2015;6:6233 pubmed 出版商

Fillmore C, Xu C, Desai P, Berry J, Rowbotham S, Lin Y, et al. EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors. Nature. 2015;520:239-42 pubmed 出版商

Verma R, Marchese A. The endosomal sorting complex required for transport pathway mediates chemokine receptor CXCR4-promoted lysosomal degradation of the mammalian target of rapamycin antagonist DEPTOR. J Biol Chem. 2015;290:6810-24 pubmed 出版商

Lindsey Boltz L, Kemp M, Capp C, Sancar A. RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling. Cell Cycle. 2015;14:99-108 pubmed 出版商

Wijeweera A, Haj M, Feldman A, Pnueli L, Luo Z, Melamed P. Gonadotropin gene transcription is activated by menin-mediated effects on the chromatin. Biochim Biophys Acta. 2015;1849:328-41 pubmed 出版商

Kanazawa I, Canaff L, Abi Rafeh J, Angrula A, Li J, Riddle R, et al. Osteoblast menin regulates bone mass in vivo. J Biol Chem. 2015;290:3910-24 pubmed 出版商

Imajo M, Ebisuya M, Nishida E. Dual role of YAP and TAZ in renewal of the intestinal epithelium. Nat Cell Biol. 2015;17:7-19 pubmed 出版商

Zou J, Zhang D, Qin G, Chen X, Wang H, Zhang D. BRCA1 and FancJ cooperatively promote interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1. Cell Cycle. 2014;13:3685-97 pubmed 出版商

Freund A, Zhong F, Venteicher A, Meng Z, Veenstra T, Frydman J, et al. Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1. Cell. 2014;159:1389-403 pubmed 出版商

Kuo P, Huang C, Lee C, Chang H, Hsieh S, Chung Y, et al. BCAS2 promotes prostate cancer cells proliferation by enhancing AR mRNA transcription and protein stability. Br J Cancer. 2015;112:391-402 pubmed 出版商

Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, et al. Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B. J Biol Chem. 2015;290:1269-80 pubmed 出版商

Izawa D, Pines J. The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C. Nature. 2015;517:631-4 pubmed 出版商

Goren I, Pfeilschifter J, Frank S. Uptake of neutrophil-derived Ym1 protein distinguishes wound macrophages in the absence of interleukin-4 signaling in murine wound healing. Am J Pathol. 2014;184:3249-61 pubmed 出版商

Liang Y, Eng W, Colquhoun D, Dinglasan R, Graham D, Mahal L. Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. J Biol Chem. 2014;289:32526-37 pubmed 出版商

Young D, Fong D, Lawlor P, Wu A, Mouravlev A, McRae M, et al. Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy. Gene Ther. 2014;21:1029-40 pubmed 出版商

Merabova N, Sariyer I, Saribas A, Knezevic T, Gordon J, Turco M, et al. WW domain of BAG3 is required for the induction of autophagy in glioma cells. J Cell Physiol. 2015;230:831-41 pubmed 出版商

Cherepanova N, Shrimal S, Gilmore R. Oxidoreductase activity is necessary for N-glycosylation of cysteine-proximal acceptor sites in glycoproteins. J Cell Biol. 2014;206:525-39 pubmed 出版商

Deng W, Rupon J, Krivega I, Breda L, Motta I, Jahn K, et al. Reactivation of developmentally silenced globin genes by forced chromatin looping. Cell. 2014;158:849-860 pubmed 出版商

Xu R, Hu Q, Ma Q, Liu C, Wang G. The protease Omi regulates mitochondrial biogenesis through the GSK3β/PGC-1α pathway. Cell Death Dis. 2014;5:e1373 pubmed 出版商

Winter G, Radic B, Mayor Ruiz C, Blomen V, Trefzer C, Kandasamy R, et al. The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity. Nat Chem Biol. 2014;10:768-773 pubmed 出版商

Booth A, Tarafder A, Hume A, Recchi C, Seabra M. A role for Na+,K+-ATPase ?1 in regulating Rab27a localisation on melanosomes. PLoS ONE. 2014;9:e102851 pubmed 出版商

Ro S, Semple I, Park H, Park H, Park H, Kim M, et al. Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1. FEBS J. 2014;281:3816-27 pubmed 出版商

Toyoda S, Yoshimura T, Mizuta J, Miyazaki J. Auto-regulation of the Sohlh1 gene by the SOHLH2/SOHLH1/SP1 complex: implications for early spermatogenesis and oogenesis. PLoS ONE. 2014;9:e101681 pubmed 出版商

Zhang P, Gao K, Tang Y, Jin X, An J, Yu H, et al. Destruction of DDIT3/CHOP protein by wild-type SPOP but not prostate cancer-associated mutants. Hum Mutat. 2014;35:1142-51 pubmed 出版商

Wijayatunge R, Chen L, Cha Y, Zannas A, Frank C, West A. The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival. Mol Cell Neurosci. 2014;61:187-200 pubmed 出版商

Choi Y, Kim Y, Jeong H, Jin Y, Yeo C, Lee K. Akt enhances Runx2 protein stability by regulating Smurf2 function during osteoblast differentiation. FEBS J. 2014;281:3656-66 pubmed 出版商

Sun H, Liu Y, Hunter T. Multiple Arkadia/RNF111 structures coordinate its Polycomb body association and transcriptional control. Mol Cell Biol. 2014;34:2981-95 pubmed 出版商

Kobayashi T, Masoumi K, Massoumi R. Deubiquitinating activity of CYLD is impaired by SUMOylation in neuroblastoma cells. Oncogene. 2015;34:2251-60 pubmed 出版商

Hayashi A, Suenaga N, Shiomi Y, Nishitani H. PCNA-dependent ubiquitination of Cdt1 and p21 in mammalian cells. Methods Mol Biol. 2014;1170:367-82 pubmed 出版商

Kadota S, Nagata K. Silencing of IFN-stimulated gene transcription is regulated by histone H1 and its chaperone TAF-I. Nucleic Acids Res. 2014;42:7642-53 pubmed 出版商

Popow J, Jurkin J, Schleiffer A, Martinez J. Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors. Nature. 2014;511:104-7 pubmed 出版商

Cooper S, Dienstbier M, Hassan R, Schermelleh L, Sharif J, Blackledge N, et al. Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment. Cell Rep. 2014;7:1456-1470 pubmed 出版商

Piazza I, Rutkowska A, Ori A, Walczak M, Metz J, Pelechano V, et al. Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits. Nat Struct Mol Biol. 2014;21:560-8 pubmed 出版商

Munoz M, Yanez D, Stark J. An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells. Nucleic Acids Res. 2014;42:7720-33 pubmed 出版商

Hans F, Fiesel F, Strong J, J ckel S, Rasse T, Geisler S, et al. UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 protein ubiquitination. J Biol Chem. 2014;289:19164-79 pubmed 出版商

Li C, Egloff A, Sen M, Grandis J, Johnson D. Caspase-8 mutations in head and neck cancer confer resistance to death receptor-mediated apoptosis and enhance migration, invasion, and tumor growth. Mol Oncol. 2014;8:1220-30 pubmed 出版商

Duda K, Lonowski L, Kofoed Nielsen M, Ibarra A, Delay C, Kang Q, et al. High-efficiency genome editing via 2A-coupled co-expression of fluorescent proteins and zinc finger nucleases or CRISPR/Cas9 nickase pairs. Nucleic Acids Res. 2014;42:e84 pubmed 出版商

Vidi P, Liu J, Salles D, Jayaraman S, Dorfman G, Gray M, et al. NuMA promotes homologous recombination repair by regulating the accumulation of the ISWI ATPase SNF2h at DNA breaks. Nucleic Acids Res. 2014;42:6365-79 pubmed 出版商

Cipriano R, Miskimen K, Bryson B, Foy C, Bartel C, Jackson M. Conserved oncogenic behavior of the FAM83 family regulates MAPK signaling in human cancer. Mol Cancer Res. 2014;12:1156-65 pubmed 出版商

Kerdivel G, Boudot A, Habauzit D, Percevault F, Demay F, Pakdel F, et al. Activation of the MKL1/actin signaling pathway induces hormonal escape in estrogen-responsive breast cancer cell lines. Mol Cell Endocrinol. 2014;390:34-44 pubmed 出版商

Hu B, Li S, Zhang X, Zheng X. HSCARG, a novel regulator of H2A ubiquitination by downregulating PRC1 ubiquitin E3 ligase activity, is essential for cell proliferation. Nucleic Acids Res. 2014;42:5582-93 pubmed 出版商

Havel J, Li Z, Cheng D, Peng J, Fu H. Nuclear PRAS40 couples the Akt/mTORC1 signaling axis to the RPL11-HDM2-p53 nucleolar stress response pathway. Oncogene. 2015;34:1487-98 pubmed 出版商

Rappe U, Schlechter T, Aschoff M, Hotz Wagenblatt A, Hofmann I. Nuclear ARVCF protein binds splicing factors and contributes to the regulation of alternative splicing. J Biol Chem. 2014;289:12421-34 pubmed 出版商

Kakiuchi K, Tsuda A, Goto Y, Shimada T, Taniguchi K, Takagishi K, et al. Cell-surface DEAD-box polypeptide 4-immunoreactive cells and gonocytes are two distinct populations in postnatal porcine testes. Biol Reprod. 2014;90:82 pubmed 出版商

Kim J, Sharma A, Dhar S, Lee S, Gu B, Chan C, et al. UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells. Cancer Res. 2014;74:1705-17 pubmed 出版商

Salvi M, Raiborg C, Hanson P, Campsteijn C, Stenmark H, Pinna L. CK2 involvement in ESCRT-III complex phosphorylation. Arch Biochem Biophys. 2014;545:83-91 pubmed 出版商

Heyne K, Förster J, Schüle R, Roemer K. Transcriptional repressor NIR interacts with the p53-inhibiting ubiquitin ligase MDM2. Nucleic Acids Res. 2014;42:3565-79 pubmed 出版商

Aida K, Hayashi H, Inamura K, Mizuno T, Sugiyama Y. Differential roles of ubiquitination in the degradation mechanism of cell surface-resident bile salt export pump and multidrug resistance-associated protein 2. Mol Pharmacol. 2014;85:482-91 pubmed 出版商

Zhang W, Ji W, Liu X, Ouyang G, Xiao W. ELL inhibits E2F1 transcriptional activity by enhancing E2F1 deacetylation via recruitment of histone deacetylase 1. Mol Cell Biol. 2014;34:765-75 pubmed 出版商

Brot S, Auger C, Bentata R, Rogemond V, Ménigoz S, Chounlamountri N, et al. Collapsin response mediator protein 5 (CRMP5) induces mitophagy, thereby regulating mitochondrion numbers in dendrites. J Biol Chem. 2014;289:2261-76 pubmed 出版商

Wang W, Wang Y, Chen H, Xing Y, Li F, Zhang Q, et al. Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway. Nat Chem Biol. 2014;10:133-40 pubmed 出版商

Kim K, Park S, Na S, Kim J, Choi H, Kim Y, et al. Reinvestigation of aminoacyl-tRNA synthetase core complex by affinity purification-mass spectrometry reveals TARSL2 as a potential member of the complex. PLoS ONE. 2013;8:e81734 pubmed 出版商

Basu A, Wilkinson F, Colavita K, Fennelly C, Atchison M. YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment. Nucleic Acids Res. 2014;42:2208-23 pubmed 出版商

Chu C, Gerstenzang E, Ossipova O, Sokol S. Lulu regulates Shroom-induced apical constriction during neural tube closure. PLoS ONE. 2013;8:e81854 pubmed 出版商

Lam T, Thomas L, White C, Li G, Pone E, Xu Z, et al. Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination. PLoS ONE. 2013;8:e80414 pubmed 出版商

Alsarraj J, Faraji F, Geiger T, Mattaini K, Williams M, Wu J, et al. BRD4 short isoform interacts with RRP1B, SIPA1 and components of the LINC complex at the inner face of the nuclear membrane. PLoS ONE. 2013;8:e80746 pubmed 出版商

Liu X, Xiao W, Wang X, Li Y, Han J, Li Y. The p38-interacting protein (p38IP) regulates G2/M progression by promoting ?-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5. J Biol Chem. 2013;288:36648-61 pubmed 出版商

Wu H, Balsbaugh J, Chandler H, Georgilis A, Zullow H, Shabanowitz J, et al. Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7. J Biol Chem. 2013;288:36398-408 pubmed 出版商

Evans C, Cook S, Coleman M, Gilley J. MEK inhibitor U0126 reverses protection of axons from Wallerian degeneration independently of MEK-ERK signaling. PLoS ONE. 2013;8:e76505 pubmed 出版商

Hashizume C, Kobayashi A, Wong R. Down-modulation of nucleoporin RanBP2/Nup358 impaired chromosomal alignment and induced mitotic catastrophe. Cell Death Dis. 2013;4:e854 pubmed 出版商

DeGennaro C, Alver B, Marguerat S, Stepanova E, Davis C, Bähler J, et al. Spt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast. Mol Cell Biol. 2013;33:4779-92 pubmed 出版商

Berndt A, Wilkinson K, Heimann M, Bishop P, Henley J. In vivo characterization of the properties of SUMO1-specific monobodies. Biochem J. 2013;456:385-95 pubmed 出版商

Verma S, Cai Q, Kreider E, Lu J, Robertson E. Comprehensive analysis of LANA interacting proteins essential for viral genome tethering and persistence. PLoS ONE. 2013;8:e74662 pubmed 出版商

Jo S, Kim M, Park J, Kim T, Ahn Y. Txnip contributes to impaired glucose tolerance by upregulating the expression of genes involved in hepatic gluconeogenesis in mice. Diabetologia. 2013;56:2723-32 pubmed 出版商

Shats I, Gatza M, Liu B, Angus S, You L, Nevins J. FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function. Cancer Res. 2013;73:6056-67 pubmed 出版商

Voss M, Campbell K, Saranzewa N, Campbell D, Hastie C, Peggie M, et al. Protein phosphatase 4 is phosphorylated and inactivated by Cdk in response to spindle toxins and interacts with ?-tubulin. Cell Cycle. 2013;12:2876-87 pubmed 出版商

Wang C, Low W, Liu A, Wang B. Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis. J Biol Chem. 2013;288:29518-29 pubmed 出版商

Gurkar A, Chu K, Raj L, Bouley R, Lee S, Kim Y, et al. Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress. Nat Commun. 2013;4:2189 pubmed 出版商

Sy S, Jiang J, O W, Deng Y, Huen M. The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaks. Nucleic Acids Res. 2013;41:8572-80 pubmed 出版商

Shan L, Li X, Liu L, Ding X, Wang Q, Zheng Y, et al. GATA3 cooperates with PARP1 to regulate CCND1 transcription through modulating histone H1 incorporation. Oncogene. 2014;33:3205-16 pubmed 出版商

Wei Q, Li J, Liu T, Tong X, Ye X. Phosphorylation of minichromosome maintenance protein 7 (MCM7) by cyclin/cyclin-dependent kinase affects its function in cell cycle regulation. J Biol Chem. 2013;288:19715-25 pubmed 出版商

Boehlke C, Kotsis F, Buchholz B, Powelske C, Eckardt K, Walz G, et al. Kif3a guides microtubular dynamics, migration and lumen formation of MDCK cells. PLoS ONE. 2013;8:e62165 pubmed 出版商

Kubota S, Fukumoto Y, Aoyama K, Ishibashi K, Yuki R, Morinaga T, et al. Phosphorylation of KRAB-associated protein 1 (KAP1) at Tyr-449, Tyr-458, and Tyr-517 by nuclear tyrosine kinases inhibits the association of KAP1 and heterochromatin protein 1? (HP1?) with heterochromatin. J Biol Chem. 2013;288:17871-83 pubmed 出版商

Yasuda Inoue M, Kuroki M, Ariumi Y. Distinct DDX DEAD-box RNA helicases cooperate to modulate the HIV-1 Rev function. Biochem Biophys Res Commun. 2013;434:803-8 pubmed 出版商

Tinnikov A, Samuels H. A novel cell lysis approach reveals that caspase-2 rapidly translocates from the nucleus to the cytoplasm in response to apoptotic stimuli. PLoS ONE. 2013;8:e61085 pubmed 出版商

Vogt D, Camus G, Herker E, Webster B, Tsou C, Greene W, et al. Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein. PLoS Pathog. 2013;9:e1003302 pubmed 出版商

Gurung B, Feng Z, Iwamoto D, Thiel A, Jin G, Fan C, et al. Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome. Cancer Res. 2013;73:2650-8 pubmed 出版商

Zhang J, Twelvetrees A, Lazarus J, Blasier K, Yao X, Inamdar N, et al. Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions. Cytoskeleton (Hoboken). 2013;70:215-27 pubmed 出版商

Martin N, Popov N, Aguilo F, O Loghlen A, Raguz S, Snijders A, et al. Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK?a regulation. EMBO J. 2013;32:982-95 pubmed 出版商

Lin S, Shen H, Li J, Tang S, Gu Y, Chen Z, et al. Proteomic and functional analyses reveal the role of chromatin reader SFMBT1 in regulating epigenetic silencing and the myogenic gene program. J Biol Chem. 2013;288:6238-47 pubmed 出版商

Wang Y, Dantas T, Lalor P, Dockery P, Morrison C. Promoter hijack reveals pericentrin functions in mitosis and the DNA damage response. Cell Cycle. 2013;12:635-46 pubmed 出版商

Dettmer U, Newman A, Luth E, Bartels T, Selkoe D. In vivo cross-linking reveals principally oligomeric forms of ?-synuclein and ?-synuclein in neurons and non-neural cells. J Biol Chem. 2013;288:6371-85 pubmed 出版商

Moreno Garcia M, Sommer K, Rincón Arano H, Brault M, Ninomiya Tsuji J, Matesic L, et al. Kinase-independent feedback of the TAK1/TAB1 complex on BCL10 turnover and NF-?B activation. Mol Cell Biol. 2013;33:1149-63 pubmed 出版商

Deguchi K, Nagamatsu G, Miyachi H, Kato Y, Morita S, Kimura H, et al. Posttranscriptional regulation of histone lysine methyltransferase GLP in embryonic male mouse germ cells. Biol Reprod. 2013;88:36 pubmed 出版商

Morlando M, Dini Modigliani S, Torrelli G, Rosa A, Di Carlo V, Caffarelli E, et al. FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment. EMBO J. 2012;31:4502-10 pubmed 出版商

Varco Merth B, Mirza K, Alzhanov D, Chia D, Rotwein P. Biochemical characterization of diverse Stat5b-binding enhancers that mediate growth hormone-activated insulin-like growth factor-I gene transcription. PLoS ONE. 2012;7:e50278 pubmed 出版商

Wang C, Kao Y, Lai P, Chen W, Chung B. Steroidogenic factor 1 (NR5A1) maintains centrosome homeostasis in steroidogenic cells by restricting centrosomal DNA-dependent protein kinase activation. Mol Cell Biol. 2013;33:476-84 pubmed 出版商

Isaacs J, Antony L, Dalrymple S, Brennen W, Gerber S, Hammers H, et al. Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment. Cancer Res. 2013;73:1386-99 pubmed 出版商

Journo C, Bonnet A, Favre Bonvin A, Turpin J, Vinera J, C t E, et al. Human T cell leukemia virus type 2 tax-mediated NF-?B activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO. J Virol. 2013;87:1123-36 pubmed 出版商

Katoh H, Okamoto T, Fukuhara T, Kambara H, Morita E, Mori Y, et al. Japanese encephalitis virus core protein inhibits stress granule formation through an interaction with Caprin-1 and facilitates viral propagation. J Virol. 2013;87:489-502 pubmed 出版商

Magli A, Schnettler E, Rinaldi F, Bremer P, Perlingeiro R. Functional dissection of Pax3 in paraxial mesoderm development and myogenesis. Stem Cells. 2013;31:59-70 pubmed 出版商

Limbo O, Moiani D, Kertokalio A, Wyman C, Tainer J, Russell P. Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair. Nucleic Acids Res. 2012;40:11435-49 pubmed 出版商

Blackford J, Guo C, Zhu R, Dougherty E, Chow C, Simons S. Identification of location and kinetically defined mechanism of cofactors and reporter genes in the cascade of steroid-regulated transactivation. J Biol Chem. 2012;287:40982-95 pubmed 出版商

Lecat A, Di Valentin E, Somja J, Jourdan S, Fillet M, Kufer T, et al. The c-Jun N-terminal kinase (JNK)-binding protein (JNKBP1) acts as a negative regulator of NOD2 protein signaling by inhibiting its oligomerization process. J Biol Chem. 2012;287:29213-26 pubmed 出版商

Boulay G, Dubuissez M, Van Rechem C, Forget A, Helin K, Ayrault O, et al. Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteins. J Biol Chem. 2012;287:10509-24 pubmed 出版商

Zhou F, Zhang X, van Dam H, Ten Dijke P, Huang H, Zhang L. Ubiquitin-specific protease 4 mitigates Toll-like/interleukin-1 receptor signaling and regulates innate immune activation. J Biol Chem. 2012;287:11002-10 pubmed 出版商

Heinz L, Rebsamen M, Rossi D, Staehli F, Schroder K, Quadroni M, et al. The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade. Cell Death Differ. 2012;19:722-31 pubmed 出版商

Wan F, Weaver A, Gao X, Bern M, Hardwidge P, Lenardo M. IKK? phosphorylation regulates RPS3 nuclear translocation and NF-?B function during infection with Escherichia coli strain O157:H7. Nat Immunol. 2011;12:335-43 pubmed 出版商

Chandrasekharan M, Huang F, Sun Z. Decoding the trans-histone crosstalk: methods to analyze H2B ubiquitination, H3 methylation and their regulatory factors. Methods. 2011;54:304-14 pubmed 出版商

Rechtsteiner A, Ercan S, Takasaki T, Phippen T, Egelhofer T, Wang W, et al. The histone H3K36 methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny. PLoS Genet. 2010;6:e1001091 pubmed 出版商

Lovric M, Hawkins C. TRAIL treatment provokes mutations in surviving cells. Oncogene. 2010;29:5048-60 pubmed 出版商

Roblek M, Schüchner S, Huber V, Ollram K, Vlcek Vesely S, Foisner R, et al. Monoclonal antibodies specific for disease-associated point-mutants: lamin A/C R453W and R482W. PLoS ONE. 2010;5:e10604 pubmed 出版商

Son J, Varadarajan S, Bratton S. TRAIL-activated stress kinases suppress apoptosis through transcriptional upregulation of MCL-1. Cell Death Differ. 2010;17:1288-301 pubmed 出版商

Nayak A, Glöckner Pagel J, Vaeth M, Schumann J, Buttmann M, Bopp T, et al. Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylase. J Biol Chem. 2009;284:10935-46 pubmed 出版商

Ramsey C, Yeung F, Stoddard P, Li D, Creutz C, Mayo M. Copine-I represses NF-kappaB transcription by endoproteolysis of p65. Oncogene. 2008;27:3516-26 pubmed 出版商

Zhao Y, Lang G, Ito S, Bonnet J, Metzger E, Sawatsubashi S, et al. A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing. Mol Cell. 2008;29:92-101 pubmed 出版商

Ying H, Furuya F, Zhao L, Araki O, West B, Hanover J, et al. Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression. J Clin Invest. 2006;116:2972-84 pubmed

Barlev N, Emelyanov A, Castagnino P, Zegerman P, Bannister A, Sepulveda M, et al. A novel human Ada2 homologue functions with Gcn5 or Brg1 to coactivate transcription. Mol Cell Biol. 2003;23:6944-57 pubmed

Kabayama H, Takeuchi M, Tokushige N, Muramatsu S, Kabayama M, Fukuda M, et al. An ultra-stable cytoplasmic antibody engineered for in vivo applications. Nat Commun. 2020;11:336 pubmed 出版商

Meena N, Jaiswal P, Chang F, Brzostowski J, Kimmel A. DPF is a cell-density sensing factor, with cell-autonomous and non-autonomous functions during Dictyostelium growth and development. BMC Biol. 2019;17:97 pubmed 出版商

Vasudevan L, Borroto Escuela D, Huysentruyt J, Fuxe K, Saini D, Stove C. Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D2 Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor. Biomolecules. 2019;9: pubmed 出版商

Nunes de Almeida F, Walther R, Pressé M, Vlassaks E, Pichaud F. Cdc42 defines apical identity and regulates epithelial morphogenesis by promoting apical recruitment of Par6-aPKC and Crumbs. Development. 2019;146: pubmed 出版商

Tang P, Miri K, Varmuza S. Unique trophoblast chromatin environment mediated by the PcG protein SFMBT2. Biol Open. 2019;8: pubmed 出版商

Park S, Yoo H, Seol J, Rhee K. HDAC3 and HDAC8 are required for cilia assembly and elongation. Biol Open. 2019;8: pubmed 出版商

Ni W, Li Y, Cai L, Dong C, Fang H, Chen Y, et al. SUMOylation is required for PIPK1γ-driven keratinocyte migration and growth. FEBS J. 2019;: pubmed 出版商

Talbot B, Vandorpe D, Stotter B, Alper S, SCHLONDORFF J. Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking and activity of the nonselective cation channel TRPC6. J Biol Chem. 2019;: pubmed 出版商

Bai M, Han Y, Wu Y, Liao J, Li L, Wang L, et al. Targeted genetic screening in mice through haploid embryonic stem cells identifies critical genes in bone development. PLoS Biol. 2019;17:e3000350 pubmed 出版商

Liu F, Fu Q, Li Y, Zhang K, Tang M, Jiang W, et al. USP21 modulates Goosecoid function through deubiquitination. Biosci Rep. 2019;39: pubmed 出版商

Rushing A, Rushing B, Hoang K, Sanders S, Peloponese J, Polakowski N, et al. HTLV-1 basic leucine zipper factor protects cells from oxidative stress by upregulating expression of Heme Oxygenase I. PLoS Pathog. 2019;15:e1007922 pubmed 出版商

Wang X, Liu R, Zhu W, Chu H, Yu H, Wei P, et al. UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis. Nature. 2019;571:127-131 pubmed 出版商

Morgan E, Macdonald A. Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1-NFκB-IL-6 signalling axis. PLoS Pathog. 2019;15:e1007835 pubmed 出版商

Zhang J, Lee Y, Dang F, Gan W, Menon A, Katon J, et al. PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage. Cancer Discov. 2019;: pubmed 出版商

Zaoui K, Boudhraa Z, Khalifé P, Carmona E, Provencher D, Mes Masson A. Ran promotes membrane targeting and stabilization of RhoA to orchestrate ovarian cancer cell invasion. Nat Commun. 2019;10:2666 pubmed 出版商

Shah B, Shimell J, Bamji S. Regulation of dendrite morphology and excitatory synapse formation by zDHHC15. J Cell Sci. 2019;: pubmed 出版商

Kono K, Yoshiura S, Fujita I, Okada Y, Shitamukai A, Shibata T, et al. Reconstruction of Par-dependent polarity in apolar cells reveals a dynamic process of cortical polarization. elife. 2019;8: pubmed 出版商

Gil Ranedo J, Gonzaga E, Jaworek K, Berger C, Bossing T, Barros C. STRIPAK Members Orchestrate Hippo and Insulin Receptor Signaling to Promote Neural Stem Cell Reactivation. Cell Rep. 2019;27:2921-2933.e5 pubmed 出版商

Aravani D, Morris G, Jones P, Tattersall H, Karamanavi E, Kaiser M, et al. HHIPL1, a Gene at the 14q32 Coronary Artery Disease Locus, Positively Regulates Hedgehog Signaling and Promotes Atherosclerosis. Circulation. 2019;140:500-513 pubmed 出版商

Inoue H, Horiguchi M, Ono K, Kanoh J. Casein kinase 2 regulates telomere protein complex formation through Rap1 phosphorylation. Nucleic Acids Res. 2019;47:6871-6884 pubmed 出版商

Grozio A, Mills K, Yoshino J, Bruzzone S, Sociali G, Tokizane K, et al. Slc12a8 is a nicotinamide mononucleotide transporter. Nat Metab. 2019;1:47-57 pubmed 出版商

Pearson S, Loft A, Rajbhandari P, Simcox J, Lee S, Tontonoz P, et al. Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism. Genes Dev. 2019;33:747-762 pubmed 出版商

Jewell J, Fu V, Hong A, Yu F, Meng D, Melick C, et al. GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. elife. 2019;8: pubmed 出版商

Fang C, Kuo H, Hsu S, Yih L. HSP70 is required for the proper assembly of pericentriolar material and function of mitotic centrosomes. Cell Div. 2019;14:4 pubmed 出版商

Petit D, Hitzenberger M, Lismont S, Zoltowska K, Ryan N, Mercken M, et al. Extracellular interface between APP and Nicastrin regulates Aβ length and response to γ-secretase modulators. EMBO J. 2019;: pubmed 出版商

Swanston A, Zabrady K, Ferreira H. The ATP-dependent chromatin remodelling enzyme Uls1 prevents Topoisomerase II poisoning. Nucleic Acids Res. 2019;47:6172-6183 pubmed 出版商

Tsarouhas V, Liu D, Tsikala G, Fedoseienko A, Zinn K, Matsuda R, et al. WASH phosphorylation balances endosomal versus cortical actin network integrities during epithelial morphogenesis. Nat Commun. 2019;10:2193 pubmed 出版商

Shang Z, Zhao J, Zhang Q, Cao C, Tian S, Zhang K, et al. USP9X-mediated deubiquitination of B-cell CLL/lymphoma 9 potentiates Wnt signaling and promotes breast carcinogenesis. J Biol Chem. 2019;294:9844-9857 pubmed 出版商

Carretero Ortega J, Chhangawala Z, Hunt S, Narvaez C, Menéndez González J, Gay C, et al. GIPC proteins negatively modulate Plexind1 signaling during vascular development. elife. 2019;8: pubmed 出版商

Cho E, Jung W, Joo H, Park E, Kim M, Kim S, et al. Cluh plays a pivotal role during adipogenesis by regulating the activity of mitochondria. Sci Rep. 2019;9:6820 pubmed 出版商

Ricketts M, Dasgupta N, Fan J, Han J, Gerace M, Tang Y, et al. The HIRA histone chaperone complex subunit UBN1 harbors H3/H4- and DNA-binding activity. J Biol Chem. 2019;294:9239-9259 pubmed 出版商

Kosztyu P, Slaninova I, Valcikova B, Verlande A, Muller P, Palecek J, et al. A Single Conserved Amino Acid Residue as a Critical Context-Specific Determinant of the Differential Ability of Mdm2 and MdmX RING Domains to Dimerize. Front Physiol. 2019;10:390 pubmed 出版商

Morwitzer M, Tritsch S, Cazares L, Ward M, Nuss J, Bavari S, et al. Identification of RUVBL1 and RUVBL2 as Novel Cellular Interactors of the Ebola Virus Nucleoprotein. Viruses. 2019;11: pubmed 出版商

Yin Q, Han T, Fang B, Zhang G, Zhang C, Roberts E, et al. K27-linked ubiquitination of BRAF by ITCH engages cytokine response to maintain MEK-ERK signaling. Nat Commun. 2019;10:1870 pubmed 出版商

Tian X, Firsanov D, Zhang Z, Cheng Y, Luo L, Tombline G, et al. SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. Cell. 2019;177:622-638.e22 pubmed 出版商

Sala D, Cunningham T, Stec M, Etxaniz U, Nicoletti C, Dall Agnese A, et al. The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration. Nat Commun. 2019;10:1796 pubmed 出版商

Hoem G, Bowitz Larsen K, Øvervatn A, Brech A, Lamark T, Sjøttem E, et al. The FMRpolyGlycine Protein Mediates Aggregate Formation and Toxicity Independent of the CGG mRNA Hairpin in a Cellular Model for FXTAS. Front Genet. 2019;10:249 pubmed 出版商

Zhang M, Wang B, Li T, Liu R, Xiao Y, Geng X, et al. Mammalian CST averts replication failure by preventing G-quadruplex accumulation. Nucleic Acids Res. 2019;47:5243-5259 pubmed 出版商

Behan F, Iorio F, Picco G, Gonçalves E, Beaver C, Migliardi G, et al. Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens. Nature. 2019;568:511-516 pubmed 出版商

Chen Z, Wang H, Wang S, Fan L, Feng S, Cai X, et al. USP9X deubiquitinates ALDH1A3 and maintains mesenchymal identity in glioblastoma stem cells. J Clin Invest. 2019;130:2043-2055 pubmed 出版商

Wauters F, Cornelissen T, Imberechts D, Martin S, Koentjoro B, Sue C, et al. LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10. Autophagy. 2019;:1-20 pubmed 出版商

Jiang Y, Zhang Y, Leung J, Fan C, Popov K, Su S, et al. MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression. Nat Commun. 2019;10:1515 pubmed 出版商

Kim C, Cho K, Kim M, Ting A. Luciferase-LOV BRET enables versatile and specific transcriptional readout of cellular protein-protein interactions. elife. 2019;8: pubmed 出版商

MacNeil D, Lambert Lanteigne P, Autexier C. N-terminal residues of human dyskerin are required for interactions with telomerase RNA that prevent RNA degradation. Nucleic Acids Res. 2019;47:5368-5380 pubmed 出版商

Baluapuri A, Hofstetter J, Dudvarski Stankovic N, Endres T, Bhandare P, Vos S, et al. MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation. Mol Cell. 2019;74:674-687.e11 pubmed 出版商

Miller C, Lou H, Simpson C, van de Kooij B, Ha B, Fisher O, et al. Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output. PLoS Biol. 2019;17:e2006540 pubmed 出版商

Cao L, Yang G, Gao S, Jing C, Montgomery R, Yin Y, et al. HIPK2 is necessary for type I interferon-mediated antiviral immunity. Sci Signal. 2019;12: pubmed 出版商

Zhou Y, Carmona S, Muhammad A, Bell S, Landeros J, Vazquez M, et al. Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model. J Clin Invest. 2019;130:1756-1771 pubmed 出版商

Peng Y, Liao Q, Tan W, Peng C, Hu Z, Chen Y, et al. The deubiquitylating enzyme USP15 regulates homologous recombination repair and cancer cell response to PARP inhibitors. Nat Commun. 2019;10:1224 pubmed 出版商

Fukushima H, Takeda H, Nakamura R. Targeted in vivo epigenome editing of H3K27me3. Epigenetics Chromatin. 2019;12:17 pubmed 出版商

Yang H, Shen H, Li J, Guo L. SIGMAR1/Sigma-1 receptor ablation impairs autophagosome clearance. Autophagy. 2019;:1-19 pubmed 出版商

Song H, Feng X, Zhang H, Luo Y, Huang J, Lin M, et al. METTL3 and ALKBH5 oppositely regulate m6A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes. Autophagy. 2019;: pubmed 出版商

Burke M, McLaurin D, Logan M, Hebert M. Alteration of 28S rRNA 2'-O-methylation by etoposide correlates with decreased SMN phosphorylation and reduced Drosha levels. Biol Open. 2019;: pubmed 出版商

Crerar H, Scott Solomon E, Bodkin Clarke C, Andreassi C, Hazbon M, Logie E, et al. Regulation of NGF Signaling by an Axonal Untranslated mRNA. Neuron. 2019;102:553-563.e8 pubmed 出版商

Logtenberg M, Jansen J, Raaben M, Toebes M, Franke K, Brandsma A, et al. Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy. Nat Med. 2019;25:612-619 pubmed 出版商

Vallardi G, Allan L, Crozier L, Saurin A. Division of labour between PP2A-B56 isoforms at the centromere and kinetochore. elife. 2019;8: pubmed 出版商

Ali H, Mano M, Braga L, Naseem A, Marini B, Vu D, et al. Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation. Nat Commun. 2019;10:926 pubmed 出版商

Gopalakrishnan R, Marr S, Kingston R, Winston F. A conserved genetic interaction between Spt6 and Set2 regulates H3K36 methylation. Nucleic Acids Res. 2019;47:3888-3903 pubmed 出版商

Wang H, Wang X, Zhang K, Wang Q, Cao X, Wang Z, et al. Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration. Sci Adv. 2019;5:eaav4971 pubmed 出版商

Munnur D, Somers J, Skalka G, Weston R, Jukes Jones R, Bhogadia M, et al. NR4A Nuclear Receptors Target Poly-ADP-Ribosylated DNA-PKcs Protein to Promote DNA Repair. Cell Rep. 2019;26:2028-2036.e6 pubmed 出版商

Ogawa Y, Shiraki T, Asano Y, Muto A, Kawakami K, Suzuki Y, et al. Six6 and Six7 coordinately regulate expression of middle-wavelength opsins in zebrafish. Proc Natl Acad Sci U S A. 2019;: pubmed 出版商

Hohl M, Remm S, Eskandarian H, Dal Molin M, Arnold F, Hürlimann L, et al. Increased drug permeability of a stiffened mycobacterial outer membrane in cells lacking MFS transporter Rv1410 and lipoprotein LprG. Mol Microbiol. 2019;111:1263-1282 pubmed 出版商

Sparrow A, Sievert K, Patel S, Chang Y, Broyles C, Brook F, et al. Measurement of Myofilament-Localized Calcium Dynamics in Adult Cardiomyocytes and the Effect of Hypertrophic Cardiomyopathy Mutations. Circ Res. 2019;124:1228-1239 pubmed 出版商

Yoon M, Kang S, Lee S, Woo T, Oh A, Park S, et al. p53 induces senescence through Lamin A/C stabilization-mediated nuclear deformation. Cell Death Dis. 2019;10:107 pubmed 出版商

Mishra P, Olafsson G, Boeckmann L, Westlake T, Jowhar Z, Dittman L, et al. Cell cycle-dependent association of polo kinase Cdc5 with CENP-A contributes to faithful chromosome segregation in budding yeast. Mol Biol Cell. 2019;30:1020-1036 pubmed 出版商

Li Z, Jiao X, Di Sante G, Ertel A, Casimiro M, Wang M, et al. Cyclin D1 integrates G9a-mediated histone methylation. Oncogene. 2019;38:4232-4249 pubmed 出版商

Möller K, Sigurbjörnsdóttir S, Arnthorsson A, Pogenberg V, Dilshat R, Fock V, et al. MITF has a central role in regulating starvation-induced autophagy in melanoma. Sci Rep. 2019;9:1055 pubmed 出版商

Riccio V, Demers N, Hua R, Vissa M, Cheng D, Strilchuk A, et al. Deubiquitinating enzyme USP30 maintains basal peroxisome abundance by regulating pexophagy. J Cell Biol. 2019;218:798-807 pubmed 出版商

Chen L, Lin Y, Gallegos D, Hazlett M, Gómez Schiavon M, Yang M, et al. Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes. Cell Rep. 2019;26:1174-1188.e5 pubmed 出版商

Koehl A, Hu H, Feng D, Sun B, Zhang Y, Robertson M, et al. Structural insights into the activation of metabotropic glutamate receptors. Nature. 2019;566:79-84 pubmed 出版商

Moshiri A, Chen R, Kim S, Harris R, Li Y, Raveendran M, et al. A nonhuman primate model of inherited retinal disease. J Clin Invest. 2019;129:863-874 pubmed 出版商

Liu B, Salgado O, Singh S, Hippen K, Maynard J, Burlingame A, et al. The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation. Nat Commun. 2019;10:354 pubmed 出版商

Profumo V, Forte B, Percio S, Rotundo F, Doldi V, Ferrari E, et al. LEADeR role of miR-205 host gene as long noncoding RNA in prostate basal cell differentiation. Nat Commun. 2019;10:307 pubmed 出版商

Guo H, Ci X, Ahmed M, Hua J, Soares F, Lin D, et al. ONECUT2 is a driver of neuroendocrine prostate cancer. Nat Commun. 2019;10:278 pubmed 出版商

Liu S, Liu L, Xu G, Cao Z, Wang Q, Li S, et al. Epigenetic Modification Is Regulated by the Interaction of Influenza A Virus Nonstructural Protein 1 with the De Novo DNA Methyltransferase DNMT3B and Subsequent Transport to the Cytoplasm for K48-Linked Polyubiquitination. J Virol. 2019;93: pubmed 出版商

Chow H, Cheng A, Song X, Swerdel M, Hart R, Herrup K. ATM is activated by ATP depletion and modulates mitochondrial function through NRF1. J Cell Biol. 2019;218:909-928 pubmed 出版商

Henriksson J, Chen X, Gomes T, Ullah U, Meyer K, Miragaia R, et al. Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation. Cell. 2019;176:882-896.e18 pubmed 出版商

Hannaford M, Loyer N, Tonelli F, Zoltner M, Januschke J. A chemical-genetics approach to study the role of atypical Protein Kinase C in Drosophila. Development. 2019;146: pubmed 出版商

Yuan S, Chu H, Chan J, Ye Z, Wen L, Yan B, et al. SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target. Nat Commun. 2019;10:120 pubmed 出版商

Chen Z, Lei C, Wang C, Li N, Srivastava M, Tang M, et al. Global phosphoproteomic analysis reveals ARMC10 as an AMPK substrate that regulates mitochondrial dynamics. Nat Commun. 2019;10:104 pubmed 出版商

Springgay L, Fitzpatrick K, Park B, Estep R, Wong S. Rhesus Macaque Rhadinovirus Encodes a Viral Interferon Regulatory Factor To Disrupt Promyelocytic Leukemia Nuclear Bodies and Antagonize Type I Interferon Signaling. J Virol. 2019;93: pubmed 出版商

Kolliopoulos C, Raja E, Razmara M, Heldin P, Heldin C, Moustakas A, et al. Transforming growth factor β (TGFβ) induces NUAK kinase expression to fine-tune its signaling output. J Biol Chem. 2019;294:4119-4136 pubmed 出版商

BRANDT C, McFie P, Vu H, Chumala P, Katselis G, Stone S. Identification of calnexin as a diacylglycerol acyltransferase-2 interacting protein. PLoS ONE. 2019;14:e0210396 pubmed 出版商

Agajanian M, Walker M, Axtman A, Ruela de Sousa R, Serafin D, Rabinowitz A, et al. WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop. Cell Rep. 2019;26:79-93.e8 pubmed 出版商

Liu Y, Qin S, Chen T, Lei M, Dhar S, Ho J, et al. Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4. Nat Commun. 2019;10:36 pubmed 出版商

Mangeot P, Risson V, Fusil F, Marnef A, Laurent E, Blin J, et al. Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins. Nat Commun. 2019;10:45 pubmed 出版商

Ramón Vázquez A, de la Rosa J, Tabraue C, Lopez F, Díaz Chico B, Bosca L, et al. Common and Differential Transcriptional Actions of Nuclear Receptors Liver X Receptors α and β in Macrophages. Mol Cell Biol. 2019;39: pubmed 出版商

Xu B, Li Q, Chen N, Zhu C, Meng Q, Ayyanathan K, et al. The LIM protein Ajuba recruits DBC1 and CBP/p300 to acetylate ERα and enhances ERα target gene expression in breast cancer cells. Nucleic Acids Res. 2019;47:2322-2335 pubmed 出版商

Chou A, Aslanian A, Sun H, Hunter T. An internal ribosome entry site in the coding region of tyrosyl-DNA phosphodiesterase 2 drives alternative translation start. J Biol Chem. 2019;294:2665-2677 pubmed 出版商

Haldeman J, Conway A, Arlotto M, Slentz D, Muoio D, Becker T, et al. Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing. Nucleic Acids Res. 2019;47:e23 pubmed 出版商

Irieda H, Inoue Y, Mori M, Yamada K, Oshikawa Y, Saitoh H, et al. Conserved fungal effector suppresses PAMP-triggered immunity by targeting plant immune kinases. Proc Natl Acad Sci U S A. 2019;116:496-505 pubmed 出版商

Lambert J, Picaud S, Fujisawa T, Hou H, Savitsky P, Uusküla Reimand L, et al. Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains. Mol Cell. 2019;73:621-638.e17 pubmed 出版商

Fenizia C, Bottino C, Corbetta S, Fittipaldi R, Floris P, Gaudenzi G, et al. SMYD3 promotes the epithelial-mesenchymal transition in breast cancer. Nucleic Acids Res. 2019;47:1278-1293 pubmed 出版商

Albig C, Tikhonova E, Krause S, Maksimenko O, Regnard C, Becker P. Factor cooperation for chromosome discrimination in Drosophila. Nucleic Acids Res. 2019;47:1706-1724 pubmed 出版商

Chae Y, Kim J, Park J, Kim K, Oh H, Lee K, et al. FOXO1 degradation via G9a-mediated methylation promotes cell proliferation in colon cancer. Nucleic Acids Res. 2019;47:1692-1705 pubmed 出版商

Adame García S, Cervantes Villagrana R, Orduña Castillo L, Del Rio J, Gutkind J, Reyes Cruz G, et al. cAMP-dependent activation of the Rac guanine exchange factor P-REX1 by type I protein kinase A (PKA) regulatory subunits. J Biol Chem. 2019;294:2232-2246 pubmed 出版商

Inoue S, Hayashi K, Fujita K, Tagawa K, Okazawa H, Kubo K, et al. Drebrin-like (Dbnl) Controls Neuronal Migration via Regulating N-Cadherin Expression in the Developing Cerebral Cortex. J Neurosci. 2019;39:678-691 pubmed 出版商

Zhou H, Zhang R, Anand P, Stomberski C, Qian Z, Hausladen A, et al. Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury. Nature. 2019;565:96-100 pubmed 出版商

Hu C, Inoue H, Sun W, Takeshita Y, Huang Y, Xu Y, et al. Structural insights into chromosome attachment to the nuclear envelope by an inner nuclear membrane protein Bqt4 in fission yeast. Nucleic Acids Res. 2019;47:1573-1584 pubmed 出版商

Nogimori T, Nishiura K, Kawashima S, Nagai T, Oishi Y, Hosoda N, et al. Dom34 mediates targeting of exogenous RNA in the antiviral OAS/RNase L pathway. Nucleic Acids Res. 2019;47:432-449 pubmed 出版商

Chang H, Kao C, Chung S, Chen W, Aninda L, Chen Y, et al. Bhlhe40 differentially regulates the function and number of peroxisomes and mitochondria in myogenic cells. Redox Biol. 2019;20:321-333 pubmed 出版商

Oravcová M, Gadaleta M, Nie M, Reubens M, Limbo O, Russell P, et al. Brc1 Promotes the Focal Accumulation and SUMO Ligase Activity of Smc5-Smc6 during Replication Stress. Mol Cell Biol. 2019;39: pubmed 出版商

Jang Y, Broun A, Wang C, Park Y, Zhuang L, Lee J, et al. H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development. Nucleic Acids Res. 2019;47:607-620 pubmed 出版商

Yi D, An N, Liu Z, Xu F, Raniga K, Li Q, et al. Human MxB Inhibits the Replication of Hepatitis C Virus. J Virol. 2019;93: pubmed 出版商

Neubauer H, Tea M, Zebol J, Gliddon B, Stefanidis C, Moretti P, et al. Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma. Oncogene. 2019;38:1151-1165 pubmed 出版商

Son S, Park S, Lee H, Siddiqi F, Lee J, Menzies F, et al. Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A. Cell Metab. 2019;29:192-201.e7 pubmed 出版商

Nnah I, Wang B, Saqcena C, Weber G, Bonder E, Bagley D, et al. TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy. Autophagy. 2019;15:151-164 pubmed 出版商

Liu J, Song T, Zhou W, Xing L, Wang S, Ho M, et al. A genome-scale CRISPR-Cas9 screening in myeloma cells identifies regulators of immunomodulatory drug sensitivity. Leukemia. 2019;33:171-180 pubmed 出版商

Kim S, Jin H, Seo H, Lee H, Lee Y. Regulating BRCA1 protein stability by cathepsin S-mediated ubiquitin degradation. Cell Death Differ. 2019;26:812-825 pubmed 出版商

Simon C, Zhang L, Wu T, Cai W, Saiz N, Nowotschin S, et al. A Gata4 nuclear GFP transcriptional reporter to study endoderm and cardiac development in the mouse. Biol Open. 2018;7: pubmed 出版商

Sabbir M. Loss of Ca2+/Calmodulin Dependent Protein Kinase Kinase 2 Leads to Aberrant Transferrin Phosphorylation and Trafficking: A Potential Biomarker for Alzheimer's Disease. Front Mol Biosci. 2018;5:99 pubmed 出版商

Mu W, Starmer J, Yee D, Magnuson T. EZH2 variants differentially regulate polycomb repressive complex 2 in histone methylation and cell differentiation. Epigenetics Chromatin. 2018;11:71 pubmed 出版商

Pettinati I, Grzechnik P, Ribeiro de Almeida C, Brem J, McDonough M, Dhir S, et al. Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease. elife. 2018;7: pubmed 出版商

Tian S, Muneeruddin K, Choi M, Tao L, Bhuiyan R, Ohmi Y, et al. Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation. PLoS Biol. 2018;16:e2006951 pubmed 出版商

Chin H, Li M, Tan I, Ninnis R, Reljic B, Scicluna K, et al. VDAC2 enables BAX to mediate apoptosis and limit tumor development. Nat Commun. 2018;9:4976 pubmed 出版商

Jangra R, Herbert A, Li R, Jae L, Kleinfelter L, Slough M, et al. Protocadherin-1 is essential for cell entry by New World hantaviruses. Nature. 2018;563:559-563 pubmed 出版商

Ding S, Zhu S, Ren L, Feng N, Song Y, Ge X, et al. Rotavirus VP3 targets MAVS for degradation to inhibit type III interferon expression in intestinal epithelial cells. elife. 2018;7: pubmed 出版商

Voytyuk I, Mueller S, Herber J, Snellinx A, Moechars D, Van Loo G, et al. BACE2 distribution in major brain cell types and identification of novel substrates. Life Sci Alliance. 2018;1:e201800026 pubmed 出版商

El Daher M, Cagnard N, Gil M, Da Cruz M, Leveau C, Sepulveda F, et al. Tetratricopeptide repeat domain 7A is a nuclear factor that modulates transcription and chromatin structure. Cell Discov. 2018;4:61 pubmed 出版商

Yuan W, Pepe Mooney B, Galli G, Dill M, Huang H, Hao M, et al. NUAK2 is a critical YAP target in liver cancer. Nat Commun. 2018;9:4834 pubmed 出版商

Alexander E, Ghanbari Niaki A, Zhang T, Sarkar J, Liu Y, Nirujogi R, et al. Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation. Proc Natl Acad Sci U S A. 2018;115:E11485-E11494 pubmed 出版商

Lobo Jarne T, Nyvltová E, Pérez Pérez R, Timón Gómez A, Molinié T, Choi A, et al. Human COX7A2L Regulates Complex III Biogenesis and Promotes Supercomplex Organization Remodeling without Affecting Mitochondrial Bioenergetics. Cell Rep. 2018;25:1786-1799.e4 pubmed 出版商

Xie B, Liu X, Yang J, Cheng J, Gu J, Xue S. PIAS1 protects against myocardial ischemia-reperfusion injury by stimulating PPARγ SUMOylation. BMC Cell Biol. 2018;19:24 pubmed 出版商

Kalkat M, Resetca D, Lourenco C, Chan P, Wei Y, Shiah Y, et al. MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis. Mol Cell. 2018;72:836-848.e7 pubmed 出版商

Moreno Vicente R, Pavón D, Martin Padura I, Català Montoro M, Díez Sánchez A, Quílez Álvarez A, et al. Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP. Cell Rep. 2018;25:1622-1635.e6 pubmed 出版商

Leoz M, Kukanja P, Luo Z, Huang F, Cary D, Peterlin B, et al. HEXIM1-Tat chimera inhibits HIV-1 replication. PLoS Pathog. 2018;14:e1007402 pubmed 出版商

Moon S, Im S, Kim N, Youn H, Park U, Kim J, et al. Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis. Cell Death Dis. 2018;9:1118 pubmed 出版商

Steyaert J, Scheveneels W, Vanneste J, Van Damme P, Robberecht W, Callaerts P, et al. FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteins. Hum Mol Genet. 2018;27:4103-4116 pubmed 出版商

Kim H, Kim D, Choi S, Kim C, Oh S, Pyo K, et al. KDM3A histone demethylase functions as an essential factor for activation of JAK2-STAT3 signaling pathway. Proc Natl Acad Sci U S A. 2018;115:11766-11771 pubmed 出版商

Lao J, Ulrich K, Johnson J, Newton B, Vashisht A, Wohlschlegel J, et al. The Yeast DNA Damage Checkpoint Kinase Rad53 Targets the Exoribonuclease, Xrn1. G3 (Bethesda). 2018;8:3931-3944 pubmed 出版商

Xian X, Pohlkamp T, Durakoglugil M, Wong C, Beck J, Lane Donovan C, et al. Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer's disease. elife. 2018;7: pubmed 出版商

Pareek G, Thomas R, Vincow E, Morris D, Pallanck L. Lon protease inactivation in Drosophila causes unfolded protein stress and inhibition of mitochondrial translation. Cell Death Discov. 2018;4:51 pubmed 出版商

Zhang M, Zhao K, Xu X, Yang Y, Yan S, Wei P, et al. A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma. Nat Commun. 2018;9:4475 pubmed 出版商

Kanaujiya J, Bastow E, Luxmi R, Hao Z, Zattas D, Hochstrasser M, et al. Rapid degradation of progressive ankylosis protein (ANKH) in craniometaphyseal dysplasia. Sci Rep. 2018;8:15710 pubmed 出版商

Liao L, Liu Z, Langbein L, Cai W, Cho E, Na J, et al. Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer. elife. 2018;7: pubmed 出版商

Bärenz F, Kschonsak Y, Meyer A, Jafarpour A, Lorenz H, Hoffmann I. Ccdc61 controls centrosomal localization of Cep170 and is required for spindle assembly and symmetry. Mol Biol Cell. 2018;:mbcE18020115 pubmed 出版商

Wang N, Dhumale P, Chiang J, Püschel A. The Sema3A receptor Plexin-A1 suppresses supernumerary axons through Rap1 GTPases. Sci Rep. 2018;8:15647 pubmed 出版商

Johnston A, Hilton D, McConnell P, Johnson B, Harris M, Simone A, et al. A novel mode of capping protein-regulation by twinfilin. elife. 2018;7: pubmed 出版商

Sheng C, Yao C, Wang Z, Chen H, Zhao Y, Xu D, et al. Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing. Nat Commun. 2018;9:4381 pubmed 出版商

Li H, Wang H, Jing M, Zhu J, Guo B, Wang Y, et al. A Phytophthora effector recruits a host cytoplasmic transacetylase into nuclear speckles to enhance plant susceptibility. elife. 2018;7: pubmed 出版商

Cha B, Geng X, Mahamud M, Zhang J, Chen L, Kim W, et al. Complementary Wnt Sources Regulate Lymphatic Vascular Development via PROX1-Dependent Wnt/β-Catenin Signaling. Cell Rep. 2018;25:571-584.e5 pubmed 出版商

Delgado Benito V, Rosen D, Wang Q, Gazumyan A, Pai J, Oliveira T, et al. The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination. Mol Cell. 2018;72:636-649.e8 pubmed 出版商

Juszkiewicz S, Chandrasekaran V, Lin Z, Kraatz S, Ramakrishnan V, Hegde R. ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol Cell. 2018;72:469-481.e7 pubmed 出版商

Tsusaka T, Kikuchi M, Shimazu T, Suzuki T, Sohtome Y, Akakabe M, et al. Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8. Epigenetics Chromatin. 2018;11:56 pubmed 出版商

Beckers A, Ott T, Schuster Gossler K, Boldt K, Alten L, Ueffing M, et al. The evolutionary conserved FOXJ1 target gene Fam183b is essential for motile cilia in Xenopus but dispensable for ciliary function in mice. Sci Rep. 2018;8:14678 pubmed 出版商

Li B, Chen J, Chao B, Zheng Y, Xiao X. A Lamin-Binding Ligand Inhibits Homologous Recombination Repair of DNA Double-Strand Breaks. ACS Cent Sci. 2018;4:1201-1210 pubmed 出版商

Takeda T, Miyazaki S, Kobayashi M, Nishino K, Goto T, Matsunaga M, et al. Zinc deficiency causes delayed ATP clearance and adenosine generation in rats and cell culture models. Commun Biol. 2018;1:113 pubmed 出版商

Mana Capelli S, McCollum D. Angiomotins stimulate LATS kinase autophosphorylation and act as scaffolds that promote Hippo signaling. J Biol Chem. 2018;293:18230-18241 pubmed 出版商

Ogmundsdóttir M, Fock V, Sooman L, Pogenberg V, Dilshat R, Bindesbøll C, et al. A short isoform of ATG7 fails to lipidate LC3/GABARAP. Sci Rep. 2018;8:14391 pubmed 出版商

Graule J, Uth K, Fischer E, Centeno I, Galvan J, Eichmann M, et al. CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway. Clin Epigenetics. 2018;10:120 pubmed 出版商

Bera R, Chiu M, Huang Y, Liang D, Lee Y, Shih L. Genetic and Epigenetic Perturbations by DNMT3A-R882 Mutants Impaired Apoptosis through Augmentation of PRDX2 in Myeloid Leukemia Cells. Neoplasia. 2018;20:1106-1120 pubmed 出版商

Yu Q, Li W, Xie D, Zheng X, Huang T, Xue P, et al. PI3Kγ promotes vascular smooth muscle cell phenotypic modulation and transplant arteriosclerosis via a SOX9-dependent mechanism. EBioMedicine. 2018;36:39-53 pubmed 出版商

Sun X, Duan Y, Qin C, Li J, Duan G, Deng X, et al. Distinct multilevel misregulations of Parkin and PINK1 revealed in cell and animal models of TDP-43 proteinopathy. Cell Death Dis. 2018;9:953 pubmed 出版商

Vigano M, Bieli D, Schaefer J, Jakob R, Matsuda S, Maier T, et al. DARPins recognizing mTFP1 as novel reagents for in vitro and in vivo protein manipulations. Biol Open. 2018;7: pubmed 出版商

Wuerth J, Habjan M, Wulle J, Superti Furga G, Pichlmair A, Weber F. NSs protein of Sandfly fever Sicilian phlebovirus counteracts interferon induction by masking the DNA-binding domain of interferon regulatory factor 3. J Virol. 2018;: pubmed 出版商

Galagovsky D, Depetris Chauvin A, Manière G, Geillon F, Berthelot Grosjean M, Noirot E, et al. Sobremesa L-type Amino Acid Transporter Expressed in Glia Is Essential for Proper Timing of Development and Brain Growth. Cell Rep. 2018;24:3156-3166.e4 pubmed 出版商

Dunn Fletcher C, Muglia L, Pavlicev M, Wolf G, Sun M, Hu Y, et al. Anthropoid primate-specific retroviral element THE1B controls expression of CRH in placenta and alters gestation length. PLoS Biol. 2018;16:e2006337 pubmed 出版商

McCloskey A, Ibarra A, Hetzer M. Tpr regulates the total number of nuclear pore complexes per cell nucleus. Genes Dev. 2018;32:1321-1331 pubmed 出版商

Richardson R, Ohlson M, Eitson J, Kumar A, McDougal M, Boys I, et al. A CRISPR screen identifies IFI6 as an ER-resident interferon effector that blocks flavivirus replication. Nat Microbiol. 2018;3:1214-1223 pubmed 出版商

Di Rita A, Peschiaroli A, D Acunzo P, Strobbe D, Hu Z, Gruber J, et al. HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα. Nat Commun. 2018;9:3755 pubmed 出版商

Drareni K, Ballaire R, Barilla S, Mathew M, Toubal A, Fan R, et al. GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation. Cell Rep. 2018;24:2957-2971.e6 pubmed 出版商

Fang H, Niu K, Mo D, Zhu Y, Tan Q, Wei D, et al. RecQL4-Aurora B kinase axis is essential for cellular proliferation, cell cycle progression, and mitotic integrity. Oncogenesis. 2018;7:68 pubmed 出版商

Ghosh C, Sathe L, Paprocki J, Raicu V, Dey M. Adaptation to Endoplasmic Reticulum Stress Requires Transphosphorylation within the Activation Loop of Protein Kinases Kin1 and Kin2, Orthologs of Human Microtubule Affinity-Regulating Kinase. Mol Cell Biol. 2018;38: pubmed 出版商

Luhtala N, Hunter T. Failure to detect functional transfer of active K-Ras protein from extracellular vesicles into recipient cells in culture. PLoS ONE. 2018;13:e0203290 pubmed 出版商

Nassrallah A, Rougée M, Bourbousse C, Drevensek S, Fonseca S, Iniesto E, et al. DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis. elife. 2018;7: pubmed 出版商

Liu X, Zhu X, Halford M, Xu T, Henkemeyer M, Xu N. Retrograde regulation of mossy fiber axon targeting and terminal maturation via postsynaptic Lnx1. J Cell Biol. 2018;217:4007-4024 pubmed 出版商

Huang L, Zhao J, Chen H, Wan L, Inuzuka H, Guo J, et al. SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis. Nat Commun. 2018;9:3569 pubmed 出版商

Ho S, Lin W. RNF144A sustains EGFR signaling to promote EGF-dependent cell proliferation. J Biol Chem. 2018;293:16307-16323 pubmed 出版商

Liu X, Cai S, Zhang C, Liu Z, Luo J, Xing B, et al. Deacetylation of NAT10 by Sirt1 promotes the transition from rRNA biogenesis to autophagy upon energy stress. Nucleic Acids Res. 2018;46:9601-9616 pubmed 出版商

Lyst M, Ekiert R, Guy J, Selfridge J, Koerner M, Merusi C, et al. Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2. Cell Rep. 2018;24:2213-2220 pubmed 出版商

Gammage P, Minczuk M. Enhanced Manipulation of Human Mitochondrial DNA Heteroplasmy In Vitro Using Tunable mtZFN Technology. Methods Mol Biol. 2018;1867:43-56 pubmed 出版商

Bonse J, Wennmann D, Kremerskothen J, Weide T, Michgehl U, Pavenstadt H, et al. Nuclear YAP localization as a key regulator of podocyte function. Cell Death Dis. 2018;9:850 pubmed 出版商

Fomin V, Richard P, Hoque M, Li C, Gu Z, Fissore O Leary M, et al. The C9ORF72 Gene, Implicated in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia, Encodes a Protein That Functions in Control of Endothelin and Glutamate Signaling. Mol Cell Biol. 2018;38: pubmed 出版商

Chen J, Cai Z, Bai M, Yu X, Zhang C, Cao C, et al. The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes. Cell Res. 2018;28:981-995 pubmed 出版商

Lee M, Han H, Han S, Kim I, Chae S, Lee C, et al. Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation. Nat Commun. 2018;9:3404 pubmed 出版商

Jung H, Kim J, Kim K, Chae Y, Hahn Y, Kim J, et al. Deacetylase activity-independent transcriptional activation by HDAC2 during TPA-induced HL-60 cell differentiation. PLoS ONE. 2018;13:e0202935 pubmed 出版商

Arii J, Watanabe M, Maeda F, Tokai Nishizumi N, Chihara T, Miura M, et al. ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity. Nat Commun. 2018;9:3379 pubmed 出版商

Lian H, Wei J, Zang R, Ye W, Yang Q, Zhang X, et al. ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response. Nat Commun. 2018;9:3349 pubmed 出版商

Abeywardana T, Oh M, Jiang L, Yang Y, Kong M, Song J, et al. CARM1 suppresses de novo serine synthesis by promoting PKM2 activity. J Biol Chem. 2018;293:15290-15303 pubmed 出版商

Duggimpudi S, Kloetgen A, Maney S, Münch P, Hezaveh K, Shaykhalishahi H, et al. Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling. J Biol Chem. 2018;293:15359-15369 pubmed 出版商

Daniel K, Icha J, Horenburg C, Müller D, Norden C, Mansfeld J. Conditional control of fluorescent protein degradation by an auxin-dependent nanobody. Nat Commun. 2018;9:3297 pubmed 出版商

Unterer B, Wiesmann V, Gunasekaran M, Sticht H, Tenkerian C, Behrens J, et al. IFN-γ-response mediator GBP-1 represses human cell proliferation by inhibiting the Hippo signaling transcription factor TEAD. Biochem J. 2018;475:2955-2967 pubmed 出版商

Hoff S, Epting D, Falk N, Schroda S, Braun D, Halbritter J, et al. The nucleoside-diphosphate kinase NME3 associates with nephronophthisis proteins and is required for ciliary function during renal development. J Biol Chem. 2018;293:15243-15255 pubmed 出版商

Bruzzone M, Grünberg S, Kubik S, Zentner G, Shore D. Distinct patterns of histone acetyltransferase and Mediator deployment at yeast protein-coding genes. Genes Dev. 2018;32:1252-1265 pubmed 出版商

Zaini M, Patel S, Syafruddin S, Rodrigues P, Vanharanta S. Endogenous HIF2A reporter systems for high-throughput functional screening. Sci Rep. 2018;8:12063 pubmed 出版商

Park J, Rhee K. E2F1 Mediates the Retinoic Acid-Induced Transcription of Tshz1 during Neuronal Differentiation in a Cell Division-Dependent Manner. Mol Cell Biol. 2018;38: pubmed 出版商

Park H, Liu G, Liu Q, Zhou Y. Swine Influenza Virus Induces RIPK1/DRP1-Mediated Interleukin-1 Beta Production. Viruses. 2018;10: pubmed 出版商

Scott A, Walker S, Krank J, Wilkinson A, Johnson K, Lewis E, et al. AIF promotes a JNK1-mediated cadherin switch independently of respiratory chain stabilization. J Biol Chem. 2018;293:14707-14722 pubmed 出版商

Mohan C, Kim L, Hollar N, Li T, Paulissen E, Leung C, et al. VivosX, a disulfide crosslinking method to capture site-specific, protein-protein interactions in yeast and human cells. elife. 2018;7: pubmed 出版商

Yu X, Lao Y, Teng X, Li S, Zhou Y, Wang F, et al. SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation. Nat Commun. 2018;9:3157 pubmed 出版商

Abe T, Kawasumi R, Giannattasio M, Dusi S, Yoshimoto Y, Miyata K, et al. AND-1 fork protection function prevents fork resection and is essential for proliferation. Nat Commun. 2018;9:3091 pubmed 出版商

Rodriguez Castaneda F, Lemma R, Cuervo I, Bengtsen M, Moen L, Ledsaak M, et al. The SUMO protease SENP1 and the chromatin remodeler CHD3 interact and jointly affect chromatin accessibility and gene expression. J Biol Chem. 2018;293:15439-15454 pubmed 出版商

Baba K, Yoshida W, Toriyama M, Shimada T, Manning C, Saito M, et al. Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance. elife. 2018;7: pubmed 出版商

Pyo J, Ryu J, Kim W, Choi J, Jeong J, Kim J. The Protein Phosphatase PPM1G Destabilizes HIF-1α Expression. Int J Mol Sci. 2018;19: pubmed 出版商

Chen M, Zhang H, Shi Z, Li Y, Zhang X, Gao Z, et al. The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer. J Biol Chem. 2018;293:14455-14469 pubmed 出版商

Nabeshima R, Nishimura O, Maeda T, Shimizu N, Ide T, Yashiro K, et al. Loss of Fam60a, a Sin3a subunit, results in embryonic lethality and is associated with aberrant methylation at a subset of gene promoters. elife. 2018;7: pubmed 出版商

Han H, Yang B, Nakaoka H, Yang J, Zhao Y, Le Nguyen K, et al. Hippo signaling dysfunction induces cancer cell addiction to YAP. Oncogene. 2018;37:6414-6424 pubmed 出版商

Zhang H, Tian J, Qi X, Xiang T, He G, Zhang H, et al. Epstein-Barr virus activates F-box protein FBXO2 to limit viral infectivity by targeting glycoprotein B for degradation. PLoS Pathog. 2018;14:e1007208 pubmed 出版商

He Q, Naqvi S, McLellan H, Boevink P, Champouret N, Hein I, et al. Plant pathogen effector utilizes host susceptibility factor NRL1 to degrade the immune regulator SWAP70. Proc Natl Acad Sci U S A. 2018;115:E7834-E7843 pubmed 出版商

Pan S, Liu X, Ma Y, Cao Y, He B. Herpes Simplex Virus 1 γ134.5 Protein Inhibits STING Activation That Restricts Viral Replication. J Virol. 2018;92: pubmed 出版商

Wang L, Chai Y, Li C, Liu H, Su W, Liu X, et al. Oxidized phospholipids are ligands for LRP6. Bone Res. 2018;6:22 pubmed 出版商

Dhar S, Bakthavatchalu V, Dhar B, Chen J, Tadahide I, Zhu H, et al. DNA polymerase gamma (Polγ) deficiency triggers a selective mTORC2 prosurvival autophagy response via mitochondria-mediated ROS signaling. Oncogene. 2018;37:6225-6242 pubmed 出版商

Ferrandino F, Bernardini G, Tsaouli G, Grazioli P, Campese A, Noce C, et al. Intrathymic Notch3 and CXCR4 combinatorial interplay facilitates T-cell leukemia propagation. Oncogene. 2018;37:6285-6298 pubmed 出版商

Qian K, Wang S, Fu M, Zhou J, Singh J, Li M, et al. Transcriptional regulation of O-GlcNAc homeostasis is disrupted in pancreatic cancer. J Biol Chem. 2018;293:13989-14000 pubmed 出版商

Darnell A, Subramaniam A, O Shea E. Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells. Mol Cell. 2018;71:229-243.e11 pubmed 出版商

Lamriben L, Oster M, Tamura T, Tian W, Yang Z, Clausen H, et al. EDEM1's mannosidase-like domain binds ERAD client proteins in a redox-sensitive manner and possesses catalytic activity. J Biol Chem. 2018;293:13932-13945 pubmed 出版商

Gow C, Liu Y, Li H, Hsieh M, Chang S, Luo S, et al. Oncogenic Function of a KIF5B-MET Fusion Variant in Non-Small Cell Lung Cancer. Neoplasia. 2018;20:838-847 pubmed 出版商

Shen Y, Bassett M, Gurumurthy A, Nar R, Knudson I, Guy C, et al. Identification of a Novel Enhancer/Chromatin Opening Element Associated with High-Level γ-Globin Gene Expression. Mol Cell Biol. 2018;38: pubmed 出版商

Inoue T, Zhang P, Zhang W, Goodner Bingham K, Dupzyk A, DiMaio D, et al. γ-Secretase promotes membrane insertion of the human papillomavirus L2 capsid protein during virus infection. J Cell Biol. 2018;217:3545-3559 pubmed 出版商

Ma J, Ketkar H, Geng T, Lo E, Wang L, Xi J, et al. Zika Virus Non-structural Protein 4A Blocks the RLR-MAVS Signaling. Front Microbiol. 2018;9:1350 pubmed 出版商

Mandon E, Butova C, Lachapelle A, Gilmore R. Conserved motifs on the cytoplasmic face of the protein translocation channel are critical for the transition between resting and active conformations. J Biol Chem. 2018;293:13662-13672 pubmed 出版商

Giaimo B, Ferrante F, Vallejo D, Hein K, Gutiérrez Pérez I, Nist A, et al. Histone variant H2A.Z deposition and acetylation directs the canonical Notch signaling response. Nucleic Acids Res. 2018;46:8197-8215 pubmed 出版商

Ma E, Dupaigne P, Maloisel L, Guerois R, Le Cam E, Coïc E. Rad52-Rad51 association is essential to protect Rad51 filaments against Srs2, but facultative for filament formation. elife. 2018;7: pubmed 出版商

Xiong S, Lorenzen K, Couzens A, Templeton C, Rajendran D, Mao D, et al. Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment. Structure. 2018;26:1101-1115.e6 pubmed 出版商

Lu W, Tirumuru N, St Gelais C, Koneru P, Liu C, Kvaratskhelia M, et al. N6-Methyladenosine-binding proteins suppress HIV-1 infectivity and viral production. J Biol Chem. 2018;293:12992-13005 pubmed 出版商

Inoue M, Uchida Y, Edagawa M, Hirata M, Mitamura J, Miyamoto D, et al. The stress response gene ATF3 is a direct target of the Wnt/β-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells. PLoS ONE. 2018;13:e0194160 pubmed 出版商

Cheng W, He X, Jia H, Chen G, Jin Q, Long Z, et al. The cGas-Sting Signaling Pathway Is Required for the Innate Immune Response Against Ectromelia Virus. Front Immunol. 2018;9:1297 pubmed 出版商

Nakano Y, Kelly M, Rehman A, Boger E, Morell R, Kelley M, et al. Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness. Cell. 2018;174:536-548.e21 pubmed 出版商

Dafinger C, Rinschen M, Borgal L, Ehrenberg C, Basten S, Franke M, et al. Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus. Exp Mol Med. 2018;50:75 pubmed 出版商

Chang C, Huang Y, Lin Y, Lin C, Jeng J, Liu S, et al. The role of sentrin-specific protease 2 substrate recognition in TGF-?-induced tumorigenesis. Sci Rep. 2018;8:9786 pubmed 出版商

Bhargava R, Sandhu M, Muk S, Lee G, Vaidehi N, Stark J. C-NHEJ without indels is robust and requires synergistic function of distinct XLF domains. Nat Commun. 2018;9:2484 pubmed 出版商

Stein C, Jadiya P, Zhang X, McLendon J, Abouassaly G, Witmer N, et al. Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency. Cell Rep. 2018;23:3710-3720.e8 pubmed 出版商

Martina J, Puertollano R. Protein phosphatase 2A stimulates activation of TFEB and TFE3 transcription factors in response to oxidative stress. J Biol Chem. 2018;293:12525-12534 pubmed 出版商

Teves S, An L, Bhargava Shah A, Xie L, Darzacq X, Tjian R. A stable mode of bookmarking by TBP recruits RNA polymerase II to mitotic chromosomes. elife. 2018;7: pubmed 出版商

Arnold F, Hohl M, Remm S, Koliwer Brandl H, Adenau S, Chusri S, et al. A uniform cloning platform for mycobacterial genetics and protein production. Sci Rep. 2018;8:9539 pubmed 出版商

Kimura A, Kitajima M, Nishida K, Serada S, Fujimoto M, Naka T, et al. NQO1 inhibits the TLR-dependent production of selective cytokines by promoting IκB-ζ degradation. J Exp Med. 2018;215:2197-2209 pubmed 出版商

Sanchez Pupo R, Johnston D, Penuela S. N-Glycosylation Regulates Pannexin 2 Localization but Is Not Required for Interacting with Pannexin 1. Int J Mol Sci. 2018;19: pubmed 出版商

Yuan J, Ng W, Lam P, Wang Y, Xia H, Yap J, et al. The dimer-dependent catalytic activity of RAF family kinases is revealed through characterizing their oncogenic mutants. Oncogene. 2018;37:5719-5734 pubmed 出版商

Li S, Cho Y, Wang B, Li S, Jiang J. Regulation of Smoothened ubiquitylation and cell surface expression through a Cul4-DDB1-G? E3 ubiquitin ligase complex. J Cell Sci. 2018;131: pubmed 出版商

Kitamura K, Que L, Shimadu M, Koura M, Ishihara Y, Wakae K, et al. Flap endonuclease 1 is involved in cccDNA formation in the hepatitis B virus. PLoS Pathog. 2018;14:e1007124 pubmed 出版商

Schrank B, Aparicio T, Li Y, Chang W, Chait B, Gundersen G, et al. Nuclear ARP2/3 drives DNA break clustering for homology-directed repair. Nature. 2018;559:61-66 pubmed 出版商

Viau A, Bienaime F, Lukas K, Todkar A, Knoll M, Yakulov T, et al. Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney. EMBO J. 2018;37: pubmed 出版商

Gordon S, Munari M, Zagotta W. Visualizing conformational dynamics of proteins in solution and at the cell membrane. elife. 2018;7: pubmed 出版商

Zonneville J, Safina A, Truskinovsky A, Arteaga C, Bakin A. TGF-β signaling promotes tumor vasculature by enhancing the pericyte-endothelium association. BMC Cancer. 2018;18:670 pubmed 出版商

Schenk L, Ousingsawat J, Skryabin B, Schreiber R, Pavenstadt H, Kunzelmann K. Regulation and Function of TMEM16F in Renal Podocytes. Int J Mol Sci. 2018;19: pubmed 出版商

Gouot E, Bhat W, Rufiange A, Fournier E, Paquet E, Nourani A. Casein kinase 2 mediated phosphorylation of Spt6 modulates histone dynamics and regulates spurious transcription. Nucleic Acids Res. 2018;46:7612-7630 pubmed 出版商

Kim H, Shin J, Lee S, Kim T, Jang H, Suh M, et al. Cyclin-dependent kinase 1 activity coordinates the chromatin associated state of Oct4 during cell cycle in embryonic stem cells. Nucleic Acids Res. 2018;46:6544-6560 pubmed 出版商

Freixo F, Martínez Delgado P, Manso Y, Sánchez Huertas C, Lacasa C, Soriano E, et al. NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization. Nat Commun. 2018;9:2330 pubmed 出版商

Patil G, Zhao M, Song K, Hao W, Bouchereau D, Wang L, et al. TRIM41-Mediated Ubiquitination of Nucleoprotein Limits Influenza A Virus Infection. J Virol. 2018;92: pubmed 出版商

Dharmat R, Eblimit A, Robichaux M, Zhang Z, Nguyen T, Jung S, et al. SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium. J Cell Biol. 2018;217:2851-2865 pubmed 出版商

Hitzel J, Lee E, Zhang Y, Bibli S, Li X, Zukunft S, et al. Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells. Nat Commun. 2018;9:2292 pubmed 出版商

Yao F, Zhou Z, Kim J, Hang Q, Xiao Z, Ton B, et al. SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity. Nat Commun. 2018;9:2269 pubmed 出版商

Staal J, Driege Y, Haegman M, Borghi A, Hulpiau P, Lievens L, et al. Ancient Origin of the CARD-Coiled Coil/Bcl10/MALT1-Like Paracaspase Signaling Complex Indicates Unknown Critical Functions. Front Immunol. 2018;9:1136 pubmed 出版商

Castanotto D, Zhang X, Alluin J, Zhang X, Rüger J, Armstrong B, et al. A stress-induced response complex (SIRC) shuttles miRNAs, siRNAs, and oligonucleotides to the nucleus. Proc Natl Acad Sci U S A. 2018;115:E5756-E5765 pubmed 出版商

Bao L, Chen Y, Lai H, Wu S, Wang J, Hatanpaa K, et al. Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration. Nucleic Acids Res. 2018;46:6576-6591 pubmed 出版商

Limbo O, Yamada Y, Russell P. Mre11-Rad50-dependent activity of ATM/Tel1 at DNA breaks and telomeres in the absence of Nbs1. Mol Biol Cell. 2018;29:1389-1399 pubmed 出版商

Lia D, Reyes A, de Melo Campos J, Piolot T, Baijer J, Radicella J, et al. Mitochondrial maintenance under oxidative stress depends on mitochondrially localised ?-OGG1. J Cell Sci. 2018;131: pubmed 出版商

Bentley P, Tan M, McBride A, White E, Howley P. The SMC5/6 Complex Interacts with the Papillomavirus E2 Protein and Influences Maintenance of Viral Episomal DNA. J Virol. 2018;92: pubmed 出版商

Dai Y, Zhang A, Shan S, Gong Z, Zhou Z. Structural basis for recognition of 53BP1 tandem Tudor domain by TIRR. Nat Commun. 2018;9:2123 pubmed 出版商

Kasowitz S, Ma J, Anderson S, Leu N, Xu Y, Gregory B, et al. Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development. PLoS Genet. 2018;14:e1007412 pubmed 出版商

Tomida J, Takata K, Bhetawal S, Person M, Chao H, Tang D, et al. FAM35A associates with REV7 and modulates DNA damage responses of normal and BRCA1-defective cells. EMBO J. 2018;37: pubmed 出版商

Chia P, Zhong F, Niwa S, Bonnard C, Utami K, Zeng R, et al. A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability. elife. 2018;7: pubmed 出版商

Faulds K, Egelston J, Sedivy L, Mitchell M, Garimella S, Kozlowski H, et al. Glycogen synthase kinase-3 (GSK-3) activity regulates mRNA methylation in mouse embryonic stem cells. J Biol Chem. 2018;293:10731-10743 pubmed 出版商

Gu P, Jia S, Takasugi T, Smith E, Nandakumar J, HENDRICKSON E, et al. CTC1-STN1 coordinates G- and C-strand synthesis to regulate telomere length. Aging Cell. 2018;:e12783 pubmed 出版商

Ashraf S, Kudo H, Rao J, Kikuchi A, Widmeier E, Lawson J, et al. Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment. Nat Commun. 2018;9:1960 pubmed 出版商

Szenker Ravi E, Altunoglu U, Leushacke M, Bosso Lefèvre C, Khatoo M, Thi Tran H, et al. RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6. Nature. 2018;557:564-569 pubmed 出版商

Almeida M, Dietz S, Redl S, Karaulanov E, Hildebrandt A, Renz C, et al. GTSF-1 is required for formation of a functional RNA-dependent RNA Polymerase complex in Caenorhabditis elegans. EMBO J. 2018;37: pubmed 出版商

Rushing A, Hoang K, Polakowski N, Lemasson I. The Human T-Cell Leukemia Virus Type 1 Basic Leucine Zipper Factor Attenuates Repair of Double-Stranded DNA Breaks via Nonhomologous End Joining. J Virol. 2018;92: pubmed 出版商

Pianalto K, Ost K, Brown H, Alspaugh J. Characterization of additional components of the environmental pH-sensing complex in the pathogenic fungus Cryptococcus neoformans. J Biol Chem. 2018;293:9995-10008 pubmed 出版商

Lork M, Kreike M, Staal J, Beyaert R. Importance of Validating Antibodies and Small Compound Inhibitors Using Genetic Knockout Studies-T Cell Receptor-Induced CYLD Phosphorylation by IKK?/TBK1 as a Case Study. Front Cell Dev Biol. 2018;6:40 pubmed 出版商

Del Bel L, Griffiths N, Wilk R, Wei H, Blagoveshchenskaya A, Burgess J, et al. The phosphoinositide phosphatase Sac1 regulates cell shape and microtubule stability in the developing Drosophila eye. Development. 2018;145: pubmed 出版商

Ménard M, Costechareyre C, Ichim G, Blachier J, Neves D, Jarrosson Wuilleme L, et al. Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth. PLoS Biol. 2018;16:e2002912 pubmed 出版商

Buttler C, Pezeshkian N, Fernandez M, Aaron J, Norman S, Freed E, et al. Single molecule fate of HIV-1 envelope reveals late-stage viral lattice incorporation. Nat Commun. 2018;9:1861 pubmed 出版商

Kogenaru M, Isalan M. Drug-Inducible Control of Lethality Genes: A Low Background Destabilizing Domain Architecture Applied to the Gal4-UAS System in Drosophila. ACS Synth Biol. 2018;7:1496-1506 pubmed 出版商

Zhuang L, Jang Y, Park Y, Lee J, Jain S, Froimchuk E, et al. Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function. Nat Commun. 2018;9:1796 pubmed 出版商

Hossain D, Ferreira Barbosa J, Cohen E, Tsang W. HIV-1 Vpr hijacks EDD-DYRK2-DDB1DCAF1 to disrupt centrosome homeostasis. J Biol Chem. 2018;293:9448-9460 pubmed 出版商

Kawasaki N, Miwa T, Hokari S, Sakurai T, Ohmori K, Miyauchi K, et al. Long noncoding RNA NORAD regulates transforming growth factor-β signaling and epithelial-to-mesenchymal transition-like phenotype. Cancer Sci. 2018;109:2211-2220 pubmed 出版商

Qi X, Han H, Zhang H, Xu M, Li L, Chen L, et al. OVOL2 links stemness and metastasis via fine-tuning epithelial-mesenchymal transition in nasopharyngeal carcinoma. Theranostics. 2018;8:2202-2216 pubmed 出版商

Rehman I, Basu S, Das S, Bhattacharjee S, Ghosh A, Pommier Y, et al. PRMT5-mediated arginine methylation of TDP1 for the repair of topoisomerase I covalent complexes. Nucleic Acids Res. 2018;46:5601-5617 pubmed 出版商

Koshimizu T, Honda K, Nagaoka Uozumi S, Ichimura A, Kimura I, Nakaya M, et al. Complex formation between the vasopressin 1b receptor, β-arrestin-2, and the μ-opioid receptor underlies morphine tolerance. Nat Neurosci. 2018;21:820-833 pubmed 出版商

Kim H, Lee K, Kim S, Cho S, Shin H, Kim C, et al. Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection. Genome Res. 2018;28:859-868 pubmed 出版商

Sirtl S, Knoll G, Trinh D, Lang I, Siegmund D, Gross S, et al. Hypertonicity-enforced BCL-2 addiction unleashes the cytotoxic potential of death receptors. Oncogene. 2018;37:4122-4136 pubmed 出版商

Matsui C, Deng L, Minami N, Abe T, Koike K, Shoji I. Hepatitis C Virus NS5A Protein Promotes the Lysosomal Degradation of Hepatocyte Nuclear Factor 1α via Chaperone-Mediated Autophagy. J Virol. 2018;92: pubmed 出版商

Suresh S, Chavalmane A, Pillai M, Ammanathan V, Vidyadhara D, Yarreiphang H, et al. Modulation of Autophagy by a Small Molecule Inverse Agonist of ERRα Is Neuroprotective. Front Mol Neurosci. 2018;11:109 pubmed 出版商

Lal A, Krishna S, Seshasayee A. Regulation of Global Transcription in Escherichia coli by Rsd and 6S RNA. G3 (Bethesda). 2018;8:2079-2089 pubmed 出版商

Ma Z, Taruno A, Ohmoto M, Jyotaki M, Lim J, Miyazaki H, et al. CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes. Neuron. 2018;98:547-561.e10 pubmed 出版商

Yamagata A, Miyazaki Y, Yokoi N, Shigematsu H, Sato Y, Goto Ito S, et al. Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22. Nat Commun. 2018;9:1546 pubmed 出版商

Bueno M, Baldascini M, Richard S, Lowndes N. Recruitment of lysine demethylase 2A to DNA double strand breaks and its interaction with 53BP1 ensures genome stability. Oncotarget. 2018;9:15915-15930 pubmed 出版商

Lu J, Liu L, Zheng M, Li X, Wu A, Wu Q, et al. MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 function. Oncogene. 2018;37:3864-3878 pubmed 出版商

Ding S, Diep J, Feng N, Ren L, Li B, Ooi Y, et al. STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection. Nat Commun. 2018;9:1485 pubmed 出版商

Pavlaki I, Alammari F, Sun B, Clark N, Sirey T, Lee S, et al. The long non-coding RNA Paupar promotes KAP1-dependent chromatin changes and regulates olfactory bulb neurogenesis. EMBO J. 2018;37: pubmed 出版商

Yoneyama Y, Lanzerstorfer P, Niwa H, Umehara T, Shibano T, Yokoyama S, et al. IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling. elife. 2018;7: pubmed 出版商

Cretu C, Agrawal A, Cook A, Will C, Fekkes P, Smith P, et al. Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds. Mol Cell. 2018;70:265-273.e8 pubmed 出版商

Yin L, Hu S, Mei S, Sun H, Xu F, Li J, et al. CRISPR/Cas9 Inhibits Multiple Steps of HIV-1 Infection. Hum Gene Ther. 2018;29:1264-1276 pubmed 出版商

Dewari P, Southgate B, Mccarten K, Monogarov G, O Duibhir E, Quinn N, et al. An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein. elife. 2018;7: pubmed 出版商

Mendez Dorantes C, Bhargava R, Stark J. Repeat-mediated deletions can be induced by a chromosomal break far from a repeat, but multiple pathways suppress such rearrangements. Genes Dev. 2018;32:524-536 pubmed 出版商

Monte I, Ishida S, Zamarreño A, Hamberg M, Franco Zorrilla J, García Casado G, et al. Ligand-receptor co-evolution shaped the jasmonate pathway in land plants. Nat Chem Biol. 2018;14:480-488 pubmed 出版商

Cohen A, Habib A, Laor D, Yadav S, Kupiec M, Weisman R. TOR complex 2 in fission yeast is required for chromatin-mediated gene silencing and assembly of heterochromatic domains at subtelomeres. J Biol Chem. 2018;293:8138-8150 pubmed 出版商

Marshall R, Vierstra R. Proteasome storage granules protect proteasomes from autophagic degradation upon carbon starvation. elife. 2018;7: pubmed 出版商

Cook A, Deng W, Ren J, Li R, Sondek J, Bergmeier W. Calcium-induced structural rearrangements release autoinhibition in the Rap-GEF CalDAG-GEFI. J Biol Chem. 2018;293:8521-8529 pubmed 出版商

Dasgupta S, Rajapakshe K, Zhu B, Nikolai B, Yi P, Putluri N, et al. Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer. Nature. 2018;556:249-254 pubmed 出版商

Jiang P, Wang S, Zheng H, Li H, Zhang F, Su Y, et al. SIP1 participates in regulation of flowering time in rice by recruiting OsTrx1 to Ehd1. New Phytol. 2018;219:422-435 pubmed 出版商

van Rijn J, Ardy R, Kuloglu Z, Härter B, van Haaften Visser D, van der Doef H, et al. Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency. Gastroenterology. 2018;155:130-143.e15 pubmed 出版商

Guittard G, Dios Esponera A, Palmer D, Akpan I, Barr V, Manna A, et al. The Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8+ T cells. Sci Rep. 2018;8:5336 pubmed 出版商

Ye B, Liu B, Hao L, Zhu X, Yang L, Wang S, et al. Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice. Nat Commun. 2018;9:1261 pubmed 出版商

Lebeau P, Platko K, Al Hashimi A, Byun J, Lhotak S, Holzapfel N, et al. Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained. J Biol Chem. 2018;293:7329-7343 pubmed 出版商

Fu J, Huang D, Yuan F, Xie N, Li Q, Sun X, et al. TRAF-interacting protein with forkhead-associated domain (TIFA) transduces DNA damage-induced activation of NF-κB. J Biol Chem. 2018;293:7268-7280 pubmed 出版商

Qiang L, Wang J, Zhang Y, Ge P, Chai Q, Li B, et al. Mycobacterium tuberculosis Mce2E suppresses the macrophage innate immune response and promotes epithelial cell proliferation. Cell Mol Immunol. 2018;: pubmed 出版商

Wojciech S, Ahmad R, Belaid Choucair Z, Journé A, Gallet S, Dam J, et al. The orphan GPR50 receptor promotes constitutive TGFβ receptor signaling and protects against cancer development. Nat Commun. 2018;9:1216 pubmed 出版商

Vigolo M, Chambers M, Willen L, Chevalley D, Maskos K, Lammens A, et al. A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors. Nat Commun. 2018;9:1199 pubmed 出版商

Prasad H, Rao R. Histone deacetylase-mediated regulation of endolysosomal pH. J Biol Chem. 2018;293:6721-6735 pubmed 出版商

Masannat J, Purayil H, Zhang Y, Russin M, Mahmud I, Kim W, et al. βArrestin2 Mediates Renal Cell Carcinoma Tumor Growth. Sci Rep. 2018;8:4879 pubmed 出版商

Stabell A, Meyerson N, Gullberg R, Gilchrist A, Webb K, Old W, et al. Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir. elife. 2018;7: pubmed 出版商

Liu J, Huang X, Hao S, Wang Y, Liu M, Xu J, et al. Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus. Nat Commun. 2018;9:1136 pubmed 出版商

Voogdt C, Wagenaar J, van Putten J. Duplicated TLR5 of zebrafish functions as a heterodimeric receptor. Proc Natl Acad Sci U S A. 2018;115:E3221-E3229 pubmed 出版商

Fleith R, Mears H, Leong X, Sanford T, Emmott E, Graham S, et al. IFIT3 and IFIT2/3 promote IFIT1-mediated translation inhibition by enhancing binding to non-self RNA. Nucleic Acids Res. 2018;46:5269-5285 pubmed 出版商

Kimura H, Arasaki K, Ohsaki Y, Fujimoto T, Ohtomo T, Yamada J, et al. Syntaxin 17 promotes lipid droplet formation by regulating the distribution of acyl-CoA synthetase 3. J Lipid Res. 2018;59:805-819 pubmed 出版商

Zhao L, Wang W, Huang S, Yang Z, Xu L, Yang Q, et al. The RNA binding protein SORBS2 suppresses metastatic colonization of ovarian cancer by stabilizing tumor-suppressive immunomodulatory transcripts. Genome Biol. 2018;19:35 pubmed 出版商

Deng Y, Qin Y, Srikantan S, Luo A, Cheng Z, Flores S, et al. The TMEM127 human tumor suppressor is a component of the mTORC1 lysosomal nutrient-sensing complex. Hum Mol Genet. 2018;27:1794-1808 pubmed 出版商

Pancholi N, Weitzman M. Serotype-specific restriction of wild-type adenoviruses by the cellular Mre11-Rad50-Nbs1 complex. Virology. 2018;518:221-231 pubmed 出版商

Zuzow N, Ghosh A, Leonard M, Liao J, Yang B, Bennett E. Mapping the mammalian ribosome quality control complex interactome using proximity labeling approaches. Mol Biol Cell. 2018;: pubmed 出版商

Oldach L, Gorshkov K, Mills W, Zhang J, Meffert M. A biosensor for MAPK-dependent Lin28 signaling. Mol Biol Cell. 2018;29:1157-1167 pubmed 出版商

Campbell A, Shadle S, Jagannathan S, Lim J, Resnick R, Tawil R, et al. NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins. elife. 2018;7: pubmed 出版商

Kabutomori J, Beloto Silva O, Geyer R, Musa Aziz R. Lithobates catesbeianus (American Bullfrog) oocytes: a novel heterologous expression system for aquaporins. Biol Open. 2018;7: pubmed 出版商

Nishioka K, Wang X, Miyazaki H, Soejima H, Hirose S. Mbf1 ensures Polycomb silencing by protecting E(z) mRNA from degradation by Pacman. Development. 2018;145: pubmed 出版商

Hewawasam G, Dhatchinamoorthy K, Mattingly M, Seidel C, Gerton J. Chromatin assembly factor-1 (CAF-1) chaperone regulates Cse4 deposition into chromatin in budding yeast. Nucleic Acids Res. 2018;46:4440-4455 pubmed 出版商

Limpose K, Trego K, Li Z, Leung S, Sarker A, Shah J, et al. Overexpression of the base excision repair NTHL1 glycosylase causes genomic instability and early cellular hallmarks of cancer. Nucleic Acids Res. 2018;46:4515-4532 pubmed 出版商

Dodson M, Liu P, Jiang T, Ambrose A, Luo G, Rojo de la Vega M, et al. Increased O-GlcNAcylation of SNAP29 Drives Arsenic-Induced Autophagic Dysfunction. Mol Cell Biol. 2018;38: pubmed 出版商

Sørensen D, Holemans T, van Veen S, Martin S, Arslan T, Haagendahl I, et al. Parkinson disease related ATP13A2 evolved early in animal evolution. PLoS ONE. 2018;13:e0193228 pubmed 出版商

Ci Y, Li X, Chen M, Zhong J, North B, Inuzuka H, et al. SCFβ-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation. Protein Cell. 2018;9:879-889 pubmed 出版商

Shao M, Vishvanath L, Busbuso N, Hepler C, Shan B, Sharma A, et al. De novo adipocyte differentiation from Pdgfrβ+ preadipocytes protects against pathologic visceral adipose expansion in obesity. Nat Commun. 2018;9:890 pubmed 出版商

Shakyawar D, Muralikrishna B, Radha V. C3G dynamically associates with nuclear speckles and regulates mRNA splicing. Mol Biol Cell. 2018;: pubmed 出版商

Hammarlöf D, Kröger C, Owen S, Canals R, Lacharme Lora L, Wenner N, et al. Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella. Proc Natl Acad Sci U S A. 2018;115:E2614-E2623 pubmed 出版商

Gao Y, Chang M, McKay D, Na N, Zhou B, Yaeger R, et al. Allele-Specific Mechanisms of Activation of MEK1 Mutants Determine Their Properties. Cancer Discov. 2018;8:648-661 pubmed 出版商

Huang H, Weng H, Sun W, Qin X, Shi H, Wu H, et al. Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nat Cell Biol. 2018;20:285-295 pubmed 出版商

Huang F, Shao W, Fujinaga K, Peterlin B. Bromodomain-containing protein 4-independent transcriptional activation by autoimmune regulator (AIRE) and NF-κB. J Biol Chem. 2018;293:4993-5004 pubmed 出版商

Colombo A, Hsia H, Wang M, Kuhn P, Brill M, Canevazzi P, et al. Non-cell-autonomous function of DR6 in Schwann cell proliferation. EMBO J. 2018;37: pubmed 出版商

Guo D, Zhang S, Sun H, Xu X, Hao Z, Mu C, et al. Tyrosine hydroxylase down-regulation after loss of Abelson helper integration site 1 (AHI1) promotes depression via the circadian clock pathway in mice. J Biol Chem. 2018;293:5090-5101 pubmed 出版商

Noguchi A, Adachi S, Yokota N, Hatta T, Natsume T, Kawahara H. ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest. Biol Open. 2018;7: pubmed 出版商

Janke R, King G, Kupiec M, Rine J. Pivotal roles of PCNA loading and unloading in heterochromatin function. Proc Natl Acad Sci U S A. 2018;115:E2030-E2039 pubmed 出版商

Sallam T, Jones M, Thomas B, Wu X, Gilliland T, Qian K, et al. Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA. Nat Med. 2018;24:304-312 pubmed 出版商

Seo G, Kim C, Shin W, Sklan E, Eoh H, Jung J. TRIM56-mediated monoubiquitination of cGAS for cytosolic DNA sensing. Nat Commun. 2018;9:613 pubmed 出版商

Kawasaki N, Isogaya K, Dan S, Yamori T, Takano H, Yao R, et al. TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling. Cell Discov. 2018;4:1 pubmed 出版商

Páez Moscoso D, Pan L, Sigauke R, Schroeder M, Tang W, Baumann P. Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast. Nat Commun. 2018;9:587 pubmed 出版商

Bento Abreu A, Jäger G, Swinnen B, Rue L, Hendrickx S, Jones A, et al. Elongator subunit 3 (ELP3) modifies ALS through tRNA modification. Hum Mol Genet. 2018;27:1276-1289 pubmed 出版商

Borroni A, Emanuelli A, Shah P, Ilic N, Apel Sarid L, Paolini B, et al. Smurf2 regulates stability and the autophagic-lysosomal turnover of lamin A and its disease-associated form progerin. Aging Cell. 2018;17: pubmed 出版商

Uddin M, Unda B, Kwan V, Holzapfel N, White S, Chalil L, et al. OTUD7A Regulates Neurodevelopmental Phenotypes in the 15q13.3 Microdeletion Syndrome. Am J Hum Genet. 2018;102:278-295 pubmed 出版商

Park H, Liu G, Thulasi Raman S, Landreth S, Liu Q, Zhou Y. NS1 Protein of 2009 Pandemic Influenza A Virus Inhibits Porcine NLRP3 Inflammasome-Mediated Interleukin-1 Beta Production by Suppressing ASC Ubiquitination. J Virol. 2018;92: pubmed 出版商

Khoshnejad M, Brenner J, Motley W, Parhiz H, Greineder C, Villa C, et al. Molecular engineering of antibodies for site-specific covalent conjugation using CRISPR/Cas9. Sci Rep. 2018;8:1760 pubmed 出版商

Tosic M, Allen A, Willmann D, Lepper C, Kim J, Duteil D, et al. Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells. Nat Commun. 2018;9:366 pubmed 出版商

Kim Y, Kwak M, Shin J, Hayuningtyas R, Choi J, Shin J. Inflachromene inhibits autophagy through modulation of Beclin 1 activity. J Cell Sci. 2018;131: pubmed 出版商

Cheng S, Tan F, Lu Y, Liu X, Li T, Yuan W, et al. WOX11 recruits a histone H3K27me3 demethylase to promote gene expression during shoot development in rice. Nucleic Acids Res. 2018;46:2356-2369 pubmed 出版商

Li Q, Hua Y, Yang Y, He X, Zhu W, Wang J, et al. T Cell Factor 7 (TCF7)/TCF1 Feedback Controls Osteocalcin Signaling in Brown Adipocytes Independent of the Wnt/β-Catenin Pathway. Mol Cell Biol. 2018;38: pubmed 出版商

Madero Pérez J, Fdez E, Fernández B, Lara Ordóñez A, Blanca Ramírez M, Gomez Suaga P, et al. Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation. Mol Neurodegener. 2018;13:3 pubmed 出版商

Lu Y, Kim N, Jiang Y, Zhang H, Zheng D, Zhu F, et al. Cambogin suppresses dextran sulphate sodium-induced colitis by enhancing Treg cell stability and function. Br J Pharmacol. 2018;175:1085-1099 pubmed 出版商

Luo W, Zhang J, Liang L, Wang G, Li Q, Zhu P, et al. Phospholipid scramblase 1 interacts with influenza A virus NP, impairing its nuclear import and thereby suppressing virus replication. PLoS Pathog. 2018;14:e1006851 pubmed 出版商

Lao Y, Yang K, Wang Z, Sun X, Zou Q, Yu X, et al. DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages. J Biol Chem. 2018;293:3965-3980 pubmed 出版商

Cao S, Zhou K, Zhang Z, Luger K, Straight A. Constitutive centromere-associated network contacts confer differential stability on CENP-A nucleosomes in vitro and in the cell. Mol Biol Cell. 2018;29:751-762 pubmed 出版商

Liu D, Li X, Shen D, Novick P. Two subunits of the exocyst, Sec3p and Exo70p, can function exclusively on the plasma membrane. Mol Biol Cell. 2018;29:736-750 pubmed 出版商

Wang Z, Kim M, Martinez Ferrando I, Koleske A, Pandey A, Cole P. Analysis of Cellular Tyrosine Phosphorylation via Chemical Rescue of Conditionally Active Abl Kinase. Biochemistry. 2018;57:1390-1398 pubmed 出版商

Zhang S, Zhang M, Jing Y, Yin X, Ma P, Zhang Z, et al. Deubiquitinase USP13 dictates MCL1 stability and sensitivity to BH3 mimetic inhibitors. Nat Commun. 2018;9:215 pubmed 出版商

Kaneda M, Sakagami H, Hida Y, Ohtsuka T, Satou N, Ishibashi Y, et al. Synaptic localisation of SRF coactivators, MKL1 and MKL2, and their role in dendritic spine morphology. Sci Rep. 2018;8:727 pubmed 出版商

Kumar A, Shaha C. SESN2 facilitates mitophagy by helping Parkin translocation through ULK1 mediated Beclin1 phosphorylation. Sci Rep. 2018;8:615 pubmed 出版商

Graf L, Dick A, Sendker F, Barth E, Marz M, Daumke O, et al. Effects of allelic variations in the human myxovirus resistance protein A on its antiviral activity. J Biol Chem. 2018;293:3056-3072 pubmed 出版商

Lee J, Kim M, Park S, Jang Y. Tousled-like kinase 1 is a negative regulator of core transcription factors in murine embryonic stem cells. Sci Rep. 2018;8:334 pubmed 出版商

Sanchez Aparicio M, Feinman L, Garcia Sastre A, Shaw M. Paramyxovirus V Proteins Interact with the RIG-I/TRIM25 Regulatory Complex and Inhibit RIG-I Signaling. J Virol. 2018;92: pubmed 出版商

Wang W, Li G, De Wu -, Luo Z, Pan P, Tian M, et al. Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion. Nat Commun. 2018;9:106 pubmed 出版商

Bourcier R, Le Scouarnec S, Bonnaud S, Karakachoff M, Bourcereau E, Heurtebise Chrétien S, et al. Rare Coding Variants in ANGPTL6 Are Associated with Familial Forms of Intracranial Aneurysm. Am J Hum Genet. 2018;102:133-141 pubmed 出版商

Qu T, Chen F, Wang J, Zhang Y, Cheng M, Sun W, et al. PCAF-mediated acetylation of Lin28B increases let-7 biogenesis in lung adenocarcinoma H1299 cells. BMC Cancer. 2018;18:27 pubmed 出版商

E L, Zhou T, Koh S, Chuang M, Sharma R, Pujol N, et al. An Antimicrobial Peptide and Its Neuronal Receptor Regulate Dendrite Degeneration in Aging and Infection. Neuron. 2018;97:125-138.e5 pubmed 出版商

Nüchel J, Ghatak S, Zuk A, Illerhaus A, Morgelin M, Schönborn K, et al. TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators. Autophagy. 2018;14:465-486 pubmed 出版商

Kumar A, Shaha C. RBX1-mediated ubiquitination of SESN2 promotes cell death upon prolonged mitochondrial damage in SH-SY5Y neuroblastoma cells. Mol Cell Biochem. 2018;446:1-9 pubmed 出版商

Smith M, Harley M, Kemp A, Wills J, Lee M, Arends M, et al. CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis. Dev Cell. 2018;44:217-232.e11 pubmed 出版商

Ding D, Bergmaier P, Sachs P, Klangwart M, Rückert T, Bartels N, et al. The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 mediates its association with KRAB-associated protein 1 (KAP1) and KAP1 target genes. J Biol Chem. 2018;293:2711-2724 pubmed 出版商

De Jesús Pérez J, Cruz Rangel S, Espino Saldaña A, Martinez Torres A, Qu Z, Hartzell H, et al. Phosphatidylinositol 4,5-bisphosphate, cholesterol, and fatty acids modulate the calcium-activated chloride channel TMEM16A (ANO1). Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863:299-312 pubmed 出版商

Liu Y, Guo X, Hirata T, Rong Y, Motooka D, Kitajima T, et al. N-Glycan-dependent protein folding and endoplasmic reticulum retention regulate GPI-anchor processing. J Cell Biol. 2018;217:585-599 pubmed 出版商

Yan S, Shen H, Lian Q, Jin W, Zhang R, Lin X, et al. Deficiency of the AIM2-ASC Signal Uncovers the STING-Driven Overreactive Response of Type I IFN and Reciprocal Depression of Protective IFN-γ Immunity in Mycobacterial Infection. J Immunol. 2018;200:1016-1026 pubmed 出版商

Zhang X, Huang G, Xie Y, He J, Guo J, Xu X, et al. The interaction of lncRNA EZR-AS1 with SMYD3 maintains overexpression of EZR in ESCC cells. Nucleic Acids Res. 2018;46:1793-1809 pubmed 出版商

Jin L, Chun J, Pan C, Kumar A, Zhang G, Ha Y, et al. The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer. Mol Cell. 2018;69:87-99.e7 pubmed 出版商

Izadi M, Schlobinski D, Lahr M, Schwintzer L, Qualmann B, Kessels M. Cobl-like promotes actin filament formation and dendritic branching using only a single WH2 domain. J Cell Biol. 2018;217:211-230 pubmed 出版商

Sheng Y, Song Y, Li Z, Wang Y, Lin H, Cheng H, et al. RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly. Cell Death Differ. 2018;25:918-934 pubmed 出版商

Shuttleworth V, Gaughan L, Nawafa L, Mooney C, Cobb S, Sheerin N, et al. The methyltransferase SET9 regulates TGFB1 activation of renal fibroblasts via interaction with SMAD3. J Cell Sci. 2018;131: pubmed 出版商

Bao Q, Li C, Xu C, Zhang R, Zhao K, Duan Z. Porcine enterocyte protein Btnl5 negatively regulates NF-kappa B pathway by interfering p65 nuclear translocation. Gene. 2018;646:47-55 pubmed 出版商

Burr S, Caldwell A, Chong M, Beretta M, Metcalf S, Hancock M, et al. Oxygen gradients can determine epigenetic asymmetry and cellular differentiation via differential regulation of Tet activity in embryonic stem cells. Nucleic Acids Res. 2018;46:1210-1226 pubmed 出版商

Reber S, Mechtersheimer J, Nasif S, Benitez J, Colombo M, Domanski M, et al. CRISPR-Trap: a clean approach for the generation of gene knockouts and gene replacements in human cells. Mol Biol Cell. 2018;29:75-83 pubmed 出版商

Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira N, et al. Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance. Nature. 2018;553:91-95 pubmed 出版商

Bodur C, Kazyken D, Huang K, Ekim Üstünel B, Siroky K, Tooley A, et al. The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists. EMBO J. 2018;37:19-38 pubmed 出版商

Di Pascale F, Nama S, Muhuri M, Quah S, Ismail H, Chan X, et al. C/EBPβ mediates RNA polymerase III-driven transcription of oncomiR-138 in malignant gliomas. Nucleic Acids Res. 2018;46:336-349 pubmed 出版商

Ma C, Wang J. Functional studies reveal the similarities and differences between AM2 and BM2 proton channels from influenza viruses. Biochim Biophys Acta Biomembr. 2018;1860:272-280 pubmed 出版商

Polpitiya Arachchige S, Henke W, Pramanik A, Kalamvoki M, Stephens E. Analysis of Select Herpes Simplex Virus 1 (HSV-1) Proteins for Restriction of Human Immunodeficiency Virus Type 1 (HIV-1): HSV-1 gM Protein Potently Restricts HIV-1 by Preventing Intracellular Transport and Processing of Env gp160. J Virol. 2018;92: pubmed 出版商

Petersheim D, Massaad M, Lee S, Scarselli A, Cancrini C, Moriya K, et al. Mechanisms of genotype-phenotype correlation in autosomal dominant anhidrotic ectodermal dysplasia with immune deficiency. J Allergy Clin Immunol. 2018;141:1060-1073.e3 pubmed 出版商

Martel D, Beneke T, Gluenz E, Späth G, Rachidi N. Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit. Biomed Res Int. 2017;2017:4635605 pubmed 出版商

Ebelt N, Kaoud T, Edupuganti R, Van Ravenstein S, Dalby K, Van Den Berg C. A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib. Oncotarget. 2017;8:104894-104912 pubmed 出版商

Crook Z, Sevilla G, Friend D, Brusniak M, Bandaranayake A, Clarke M, et al. Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets. Nat Commun. 2017;8:2244 pubmed 出版商

Wang Y, Liu X, Zhou L, Duong D, Bhuripanyo K, Zhao B, et al. Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer. Nat Commun. 2017;8:2232 pubmed 出版商

Sinhadri B, Jin D, Stafford D, Tie J. Vitamin K epoxide reductase and its paralogous enzyme have different structures and functions. Sci Rep. 2017;7:17632 pubmed 出版商

Scherer P, Zaccor N, Neumann N, Vasavda C, Barrow R, Ewald A, et al. TRPV1 is a physiological regulator of μ-opioid receptors. Proc Natl Acad Sci U S A. 2017;114:13561-13566 pubmed 出版商

Guo X, Bai Y, Zhao M, Zhou M, Shen Q, Yun C, et al. Acetylation of 53BP1 dictates the DNA double strand break repair pathway. Nucleic Acids Res. 2017;: pubmed 出版商

Heubl M, Zhang J, Pressey J, Al Awabdh S, Renner M, Gomez Castro F, et al. GABAA receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl--sensitive WNK1 kinase. Nat Commun. 2017;8:1776 pubmed 出版商

Rodrigues J, Lydall D. Paf1 and Ctr9, core components of the PAF1 complex, maintain low levels of telomeric repeat containing RNA. Nucleic Acids Res. 2017;: pubmed 出版商

Tsuchiya Y, Osaki K, Kanamoto M, Nakao Y, Takahashi E, Higuchi T, et al. Distinct B Subunits of PP2A Regulate the NF-?B Signaling Pathway through Dephosphorylation of IKK?, I?B?, and RelA. FEBS Lett. 2017;: pubmed 出版商

Wang L, Collings C, Zhao Z, Cozzolino K, Ma Q, Liang K, et al. A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism. Genes Dev. 2017;31:2056-2066 pubmed 出版商

Zhang Y, Li J, Li B, Wang J, Liu C. Mycobacterium tuberculosis Mce3C promotes mycobacteria entry into macrophages through activation of ?2 integrin-mediated signalling pathway. Cell Microbiol. 2017;: pubmed 出版商

Thomson B, Souma T, Tompson S, Onay T, Kizhatil K, Siggs O, et al. Angiopoietin-1 is required for Schlemm's canal development in mice and humans. J Clin Invest. 2017;127:4421-4436 pubmed 出版商

D Alessandro M, Beesley S, Kim J, Jones Z, Chen R, Wi J, et al. Stability of Wake-Sleep Cycles Requires Robust Degradation of the PERIOD Protein. Curr Biol. 2017;27:3454-3467.e8 pubmed 出版商

Nakamuta S, Yang Y, Wang C, Gallo N, Yu J, Tai Y, et al. Dual role for DOCK7 in tangential migration of interneuron precursors in the postnatal forebrain. J Cell Biol. 2017;216:4313-4330 pubmed 出版商

Shpargel K, Starmer J, Wang C, Ge K, Magnuson T. UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome. Proc Natl Acad Sci U S A. 2017;114:E9046-E9055 pubmed 出版商

Zhu B, Ueda A, Song X, Horike S, Yokota T, Akagi T. Baf53a is involved in survival of mouse ES cells, which can be compensated by Baf53b. Sci Rep. 2017;7:14059 pubmed 出版商

Mochizuki M, Lorenz V, Ivanek R, Della Verde G, Gaudiello E, Marsano A, et al. Polo-Like Kinase 2 is Dynamically Regulated to Coordinate Proliferation and Early Lineage Specification Downstream of Yes-Associated Protein 1 in Cardiac Progenitor Cells. J Am Heart Assoc. 2017;6: pubmed 出版商

Sheinboim D, Maza I, Dror I, Parikh S, Krupalnik V, Bell R, et al. OCT4 impedes cell fate redirection by the melanocyte lineage master regulator MITF in mouse ESCs. Nat Commun. 2017;8:1022 pubmed 出版商

Chang E, Novoa C, Aristizabal M, Coulombe Y, Segovia R, Chaturvedi R, et al. RECQ-like helicases Sgs1 and BLM regulate R-loop-associated genome instability. J Cell Biol. 2017;216:3991-4005 pubmed 出版商

Wang A, Juan A, Ko K, Tsai P, Zare H, Dell Orso S, et al. The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins. Mol Cell. 2017;68:398-413.e6 pubmed 出版商

Rüthemann P, Balbo Pogliano C, Codilupi T, Garajova Z, Naegeli H. Chromatin remodeler CHD1 promotes XPC-to-TFIIH handover of nucleosomal UV lesions in nucleotide excision repair. EMBO J. 2017;36:3372-3386 pubmed 出版商

Gelato K, Schöckel L, Klingbeil O, Rückert T, Lesche R, Toedling J, et al. Super-enhancers define a proliferative PGC-1?-expressing melanoma subgroup sensitive to BET inhibition. Oncogene. 2017;: pubmed 出版商

Linares J, Cordes T, Duran A, Reina Campos M, Valencia T, Ahn C, et al. ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma. Cell Metab. 2017;26:817-829.e6 pubmed 出版商

Zhou H, Morales M, Hashimoto H, Dickson M, Song K, Ye W, et al. ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression. Genes Dev. 2017;31:1770-1783 pubmed 出版商

Tashiro S, Nishihara Y, Kugou K, Ohta K, Kanoh J. Subtelomeres constitute a safeguard for gene expression and chromosome homeostasis. Nucleic Acids Res. 2017;45:10333-10349 pubmed 出版商

Lavallée Adam M, Cloutier P, Coulombe B, Blanchette M. Functional 5' UTR motif discovery with LESMoN: Local Enrichment of Sequence Motifs in biological Networks. Nucleic Acids Res. 2017;45:10415-10427 pubmed 出版商

Cao H, Zhang S, Shan S, Sun C, Li Y, Yu S, et al. Ligand-dependent corepressor (LCoR) represses the transcription factor C/EBPβ during early adipocyte differentiation. J Biol Chem. 2017;292:18973-18987 pubmed 出版商

Sisakova A, Altmannova V, Sebesta M, Krejci L. Role of PCNA and RFC in promoting Mus81-complex activity. BMC Biol. 2017;15:90 pubmed 出版商

Shen Y, Kapfhamer D, Minnella A, Kim J, Won S, Chen Y, et al. Bioenergetic state regulates innate inflammatory responses through the transcriptional co-repressor CtBP. Nat Commun. 2017;8:624 pubmed 出版商

Bagati A, Bianchi Smiraglia A, Moparthy S, Kolesnikova K, Fink E, Lipchick B, et al. Melanoma Suppressor Functions of the Carcinoma Oncogene FOXQ1. Cell Rep. 2017;20:2820-2832 pubmed 出版商

Vu L, Pickering B, Cheng Y, Zaccara S, Nguyen D, Minuesa G, et al. The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. Nat Med. 2017;23:1369-1376 pubmed 出版商

Ryerson M, Richards M, Kvansakul M, Hawkins C, Shisler J. Vaccinia Virus Encodes a Novel Inhibitor of Apoptosis That Associates with the Apoptosome. J Virol. 2017;91: pubmed 出版商

Ruan H, Ma Y, Torres S, Zhang B, Feriod C, Heck R, et al. Calcium-dependent O-GlcNAc signaling drives liver autophagy in adaptation to starvation. Genes Dev. 2017;31:1655-1665 pubmed 出版商

Stiegler A, Boggon T. p190RhoGAP proteins contain pseudoGTPase domains. Nat Commun. 2017;8:506 pubmed 出版商

Chen Z, Gui B, Zhang Y, Xie G, Li W, Liu S, et al. Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly. J Biol Chem. 2017;292:18113-18128 pubmed 出版商

Wei Y, Kim T, Peng D, Duan D, Gibbons D, Yamauchi M, et al. Fibroblast-specific inhibition of TGF-?1 signaling attenuates lung and tumor fibrosis. J Clin Invest. 2017;127:3675-3688 pubmed 出版商

Papizan J, Garry G, Brezprozvannaya S, McAnally J, Bassel Duby R, Liu N, et al. Deficiency in Kelch protein Klhl31 causes congenital myopathy in mice. J Clin Invest. 2017;127:3730-3740 pubmed 出版商

Apara A, Galvão J, Wang Y, Blackmore M, Trillo A, Iwao K, et al. KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS. J Neurosci. 2017;37:9632-9644 pubmed 出版商

Shrimal S, Cherepanova N, Gilmore R. DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon. J Cell Biol. 2017;216:3625-3638 pubmed 出版商

Li Q, Liu X, Jin K, Lu M, Zhang C, Du X, et al. NAT10 is upregulated in hepatocellular carcinoma and enhances mutant p53 activity. BMC Cancer. 2017;17:605 pubmed 出版商

Kwun H, Wendzicki J, Shuda Y, Moore P, Chang Y. Merkel cell polyomavirus small T antigen induces genome instability by E3 ubiquitin ligase targeting. Oncogene. 2017;36:6784-6792 pubmed 出版商

McQueen A, Kanamaluru D, Yan K, Gray N, Wu L, Li M, et al. The C-terminal fibrinogen-like domain of angiopoietin-like 4 stimulates adipose tissue lipolysis and promotes energy expenditure. J Biol Chem. 2017;292:16122-16134 pubmed 出版商

Ning B, Zhao W, Qian C, Liu P, Li Q, Li W, et al. USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components. Nat Commun. 2017;8:349 pubmed 出版商

Lyu Y, Nakano K, Davis R, Tepper C, Campbell M, Izumiya Y. ZIC2 Is Essential for Maintenance of Latency and Is a Target of an Immediate Early Protein during Kaposi's Sarcoma-Associated Herpesvirus Lytic Reactivation. J Virol. 2017;91: pubmed 出版商

Tanaka T, Nakajima Takagi Y, Aoyama K, Tara S, Oshima M, Saraya A, et al. Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies. J Exp Med. 2017;214:2901-2913 pubmed 出版商

Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed 出版商

Tarhonskaya H, Nowak R, Johansson C, Szykowska A, Tumber A, Hancock R, et al. Studies on the Interaction of the Histone Demethylase KDM5B with Tricarboxylic Acid Cycle Intermediates. J Mol Biol. 2017;429:2895-2906 pubmed 出版商

Burr R, Ribbens D, Raychaudhuri S, Stewart E, Ho J, Espenshade P. Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast. J Biol Chem. 2017;292:16333-16350 pubmed 出版商

Galasso A, Cameron C, Frenguelli B, Moffat K. An AMPK-dependent regulatory pathway in tau-mediated toxicity. Biol Open. 2017;6:1434-1444 pubmed 出版商

Oslund R, Su X, Haugbro M, Kee J, Esposito M, David Y, et al. Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate. Nat Chem Biol. 2017;13:1081-1087 pubmed 出版商

Wang W, Perens E, Oikonomou G, Wallace S, Lu Y, Shaham S. IGDB-2, an Ig/FNIII protein, binds the ion channel LGC-34 and controls sensory compartment morphogenesis in C. elegans. Dev Biol. 2017;430:105-112 pubmed 出版商

Song C, Hotz Wagenblatt A, Voit R, Grummt I. SIRT7 and the DEAD-box helicase DDX21 cooperate to resolve genomic R loops and safeguard genome stability. Genes Dev. 2017;31:1370-1381 pubmed 出版商

Seo H, Choi Y, Kim M, Kang K, Urano T, Lee D. The 19S proteasome is directly involved in the regulation of heterochromatin spreading in fission yeast. J Biol Chem. 2017;292:17144-17155 pubmed 出版商

Yao Z, Yaeger R, Rodrik Outmezguine V, Tao A, Torres N, Chang M, et al. Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS. Nature. 2017;548:234-238 pubmed 出版商

Shi S, Buck T, Kinlough C, Marciszyn A, Hughey R, Chalfie M, et al. Regulation of the epithelial Na+ channel by paraoxonase-2. J Biol Chem. 2017;292:15927-15938 pubmed 出版商

Johnson N, Deck K, Nizzi C, Eisenstein R. A synergistic role of IRP1 and FBXL5 proteins in coordinating iron metabolism during cell proliferation. J Biol Chem. 2017;292:15976-15989 pubmed 出版商

Hughes M, Lavrencic P, Coll R, Ve T, Ryan D, Williams N, et al. Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling. Proc Natl Acad Sci U S A. 2017;114:E6480-E6489 pubmed 出版商

Leonard J, Leonard D, Wolfe S, Liu J, Rivera J, Yang M, et al. The Dkk3 gene encodes a vital intracellular regulator of cell proliferation. PLoS ONE. 2017;12:e0181724 pubmed 出版商

Judge L, Perez Bermejo J, Truong A, Ribeiro A, Yoo J, Jensen C, et al. A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress. JCI Insight. 2017;2: pubmed 出版商

Peng Y, Zhang M, Zheng L, Liang Q, Li H, Chen J, et al. Cysteine protease cathepsin B mediates radiation-induced bystander effects. Nature. 2017;547:458-462 pubmed 出版商

Gangula N, Maddika S. Interplay between the phosphatase PHLPP1 and E3 ligase RNF41 stimulates proper kinetochore assembly via the outer-kinetochore protein SGT1. J Biol Chem. 2017;292:13947-13958 pubmed 出版商

Takahashi M, Li Y, Dillon T, Kariya Y, Stork P. Phosphorylation of the C-Raf N Region Promotes Raf Dimerization. Mol Cell Biol. 2017;37: pubmed 出版商

Aslan Y, Tadjuidje E, Zorn A, Cha S. High-efficiency non-mosaic CRISPR-mediated knock-in and indel mutation in F0 Xenopus. Development. 2017;144:2852-2858 pubmed 出版商

Ly D, Resch E, Ordiway G, Dinardo S. Asymmetrically deployed actomyosin-based contractility generates a boundary between developing leg segments in Drosophila. Dev Biol. 2017;429:165-176 pubmed 出版商

Pillay S, Zou W, Cheng F, Puschnik A, Meyer N, Ganaie S, et al. Adeno-associated Virus (AAV) Serotypes Have Distinctive Interactions with Domains of the Cellular AAV Receptor. J Virol. 2017;91: pubmed 出版商

Jung C, Hawkins J, Jones S, Xiao Y, Rybarski J, Dillard K, et al. Massively Parallel Biophysical Analysis of CRISPR-Cas Complexes on Next Generation Sequencing Chips. Cell. 2017;170:35-47.e13 pubmed 出版商

Xu L, Liu X, Sheng N, Oo K, Liang J, Chionh Y, et al. Three distinct 3-methylcytidine (m3C) methyltransferases modify tRNA and mRNA in mice and humans. J Biol Chem. 2017;292:14695-14703 pubmed 出版商

Dogan T, Gnad F, Chan J, Phu L, Young A, Chen M, et al. Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling pathways to the cell cycle. J Biol Chem. 2017;292:14311-14324 pubmed 出版商

Rogov V, Stolz A, Ravichandran A, Rios Szwed D, Suzuki H, Kniss A, et al. Structural and functional analysis of the GABARAP interaction motif (GIM). EMBO Rep. 2017;18:1382-1396 pubmed 出版商

Bossi F, Fan J, Xiao J, Chandra L, Shen M, Dorone Y, et al. Systematic discovery of novel eukaryotic transcriptional regulators using sequence homology independent prediction. BMC Genomics. 2017;18:480 pubmed 出版商

Casciello F, Al Ejeh F, Kelly G, Brennan D, Ngiow S, Young A, et al. G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis. Proc Natl Acad Sci U S A. 2017;114:7077-7082 pubmed 出版商

Li L, Fan L, Zhou J, Grantham J, Calvet J, Sage J, et al. Lysine methyltransferase SMYD2 promotes cyst growth in autosomal dominant polycystic kidney disease. J Clin Invest. 2017;127:2751-2764 pubmed 出版商

Hernández Vásquez M, Adame García S, Hamoud N, Chidiac R, Reyes Cruz G, Gratton J, et al. Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock. J Biol Chem. 2017;292:12178-12191 pubmed 出版商

Tan Y, Ci Y, Dai X, Wu F, Guo J, Liu D, et al. Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6. Oncotarget. 2017;8:47890-47901 pubmed 出版商

Cheng J, Qin B, Liu B, Huang T, Li Y, Ma L. Maternal embryonic leucine zipper kinase inhibits epithelial-mesenchymal transition by regulating transforming growth factor-? signaling. Oncol Lett. 2017;13:4794-4798 pubmed 出版商

Bu P, Yagi S, Shiota K, Alam S, Vivian J, Wolfe M, et al. Origin of a rapidly evolving homeostatic control system programming testis function. J Endocrinol. 2017;234:217-232 pubmed 出版商

Simsek D, Tiu G, Flynn R, Byeon G, Leppek K, Xu A, et al. The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity. Cell. 2017;169:1051-1065.e18 pubmed 出版商

Xiao X, Yang H, Arutiunian V, Fang Y, Besse G, Morimoto C, et al. Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation. Nucleic Acids Res. 2017;45:7494-7506 pubmed 出版商

Yonezawa T, Takahashi H, Shikata S, Liu X, Tamura M, Asada S, et al. The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1. J Biol Chem. 2017;292:12528-12541 pubmed 出版商

Casimiro M, Di Sante G, Di Rocco A, Loro E, Pupo C, Pestell T, et al. Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis. Cancer Res. 2017;77:3391-3405 pubmed 出版商

Biswas S, Shisler J. Molluscum Contagiosum Virus MC159 Abrogates cIAP1-NEMO Interactions and Inhibits NEMO Polyubiquitination. J Virol. 2017;91: pubmed 出版商

Zhu W, He X, Hua Y, Li Q, Wang J, Gan X. The E3 ubiquitin ligase WWP2 facilitates RUNX2 protein transactivation in a mono-ubiquitination manner during osteogenic differentiation. J Biol Chem. 2017;292:11178-11188 pubmed 出版商

Ferrin M, Subramaniam A. Kinetic modeling predicts a stimulatory role for ribosome collisions at elongation stall sites in bacteria. elife. 2017;6: pubmed 出版商

Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, et al. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. 2017;545:365-369 pubmed 出版商

Chapat C, Jafarnejad S, Matta Camacho E, Hesketh G, Gelbart I, Attig J, et al. Cap-binding protein 4EHP effects translation silencing by microRNAs. Proc Natl Acad Sci U S A. 2017;114:5425-5430 pubmed 出版商

McRae E, Booy E, Moya Torres A, Ezzati P, Stetefeld J, McKenna S. Human DDX21 binds and unwinds RNA guanine quadruplexes. Nucleic Acids Res. 2017;45:6656-6668 pubmed 出版商

Calton C, Bronnimann M, Manson A, Li S, Chapman J, Suarez Berumen M, et al. Translocation of the papillomavirus L2/vDNA complex across the limiting membrane requires the onset of mitosis. PLoS Pathog. 2017;13:e1006200 pubmed 出版商

Zhong Y, Wang J, Henderson M, Yang P, Hagen B, Siddique T, et al. Nuclear export of misfolded SOD1 mediated by a normally buried NES-like sequence reduces proteotoxicity in the nucleus. elife. 2017;6: pubmed 出版商

Frank R, Zhu F, Komiyama N, Grant S. Hierarchical organization and genetically separable subfamilies of PSD95 postsynaptic supercomplexes. J Neurochem. 2017;142:504-511 pubmed 出版商

Wu D, Zhao L, Feng Z, Yu C, Ding J, Wang L, et al. O-Linked N-acetylglucosamine transferase 1 regulates global histone H4 acetylation via stabilization of the nonspecific lethal protein NSL3. J Biol Chem. 2017;292:10014-10025 pubmed 出版商

Zhang P, Rausch C, Hastert F, Boneva B, Filatova A, Patil S, et al. Methyl-CpG binding domain protein 1 regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner. Nucleic Acids Res. 2017;45:7118-7136 pubmed 出版商

Ashkenazi A, Bento C, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, et al. Polyglutamine tracts regulate beclin 1-dependent autophagy. Nature. 2017;545:108-111 pubmed 出版商

Tawo R, Pokrzywa W, Kevei E, Akyuz M, Balaji V, Adrian S, et al. The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover. Cell. 2017;169:470-482.e13 pubmed 出版商

Sokolowski M, Chynces M, Deharo D, Christian C, Belancio V. Truncated ORF1 proteins can suppress LINE-1 retrotransposition in trans. Nucleic Acids Res. 2017;45:5294-5308 pubmed 出版商

Kaufman D, Papillon J, Larose L, Iwawaki T, Cybulsky A. Deletion of inositol-requiring enzyme-1? in podocytes disrupts glomerular capillary integrity and autophagy. Mol Biol Cell. 2017;28:1636-1651 pubmed 出版商

Blank M, Chen S, Poetz F, Schnolzer M, Voit R, Grummt I. SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription. Nucleic Acids Res. 2017;45:2675-2686 pubmed 出版商

Woo T, Yoon M, Hong S, Choi J, Ha N, Sun H, et al. Anti-cancer effect of novel PAK1 inhibitor via induction of PUMA-mediated cell death and p21-mediated cell cycle arrest. Oncotarget. 2017;8:23690-23701 pubmed 出版商

Beautrait A, Paradis J, Zimmerman B, Giubilaro J, Nikolajev L, Armando S, et al. A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling. Nat Commun. 2017;8:15054 pubmed 出版商

Zykova T, Zhu F, Wang L, Li H, Bai R, Lim D, et al. The T-LAK Cell-originated Protein Kinase Signal Pathway Promotes Colorectal Cancer Metastasis. EBioMedicine. 2017;18:73-82 pubmed 出版商

Rajgor D, Fiuza M, Parkinson G, Hanley J. The PICK1 Ca2+ sensor modulates N-methyl-d-aspartate (NMDA) receptor-dependent microRNA-mediated translational repression in neurons. J Biol Chem. 2017;292:9774-9786 pubmed 出版商

Strickson S, Emmerich C, Goh E, Zhang J, Kelsall I, MacArtney T, et al. Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling. Proc Natl Acad Sci U S A. 2017;114:E3481-E3489 pubmed 出版商

Sen R, Kaja A, Ferdoush J, Lahudkar S, Barman P, Bhaumik S. An mRNA Capping Enzyme Targets FACT to the Active Gene To Enhance the Engagement of RNA Polymerase II into Transcriptional Elongation. Mol Cell Biol. 2017;37: pubmed 出版商

Litwin I, Bakowski T, Maciaszczyk Dziubinska E, Wysocki R. The LSH/HELLS homolog Irc5 contributes to cohesin association with chromatin in yeast. Nucleic Acids Res. 2017;45:6404-6416 pubmed 出版商

Sokol E, Feng Y, Jin D, Tizabi M, Miller D, Cohen M, et al. SMARCE1 is required for the invasive progression of in situ cancers. Proc Natl Acad Sci U S A. 2017;114:4153-4158 pubmed 出版商

Hirano M, Takada Y, Wong C, Yamaguchi K, Kotani H, Kurokawa T, et al. C-terminal splice variants of P/Q-type Ca2+ channel CaV2.1 ?1 subunits are differentially regulated by Rab3-interacting molecule proteins. J Biol Chem. 2017;292:9365-9381 pubmed 出版商

Miedlich S, Taya M, Young M, Hammes S. Paxillin and embryonic PolyAdenylation Binding Protein (ePABP) engage to regulate androgen-dependent Xenopus laevis oocyte maturation - A model of kinase-dependent regulation of protein expression. Mol Cell Endocrinol. 2017;448:87-97 pubmed 出版商

Zhang Z, Guo X, Ge C, Ma Z, Jiang M, Li T, et al. KETCH1 imports HYL1 to nucleus for miRNA biogenesis in Arabidopsis. Proc Natl Acad Sci U S A. 2017;114:4011-4016 pubmed 出版商

Carnesecchi J, Forcet C, Zhang L, Tribollet V, Barenton B, Boudra R, et al. ERR? induces H3K9 demethylation by LSD1 to promote cell invasion. Proc Natl Acad Sci U S A. 2017;114:3909-3914 pubmed 出版商

Kawaai K, Ando H, Satoh N, Yamada H, Ogawa N, Hirose M, et al. Splicing variation of Long-IRBIT determines the target selectivity of IRBIT family proteins. Proc Natl Acad Sci U S A. 2017;114:3921-3926 pubmed 出版商

Dong X, Guan J, Zheng C, Zheng X. The herpes simplex virus 1 UL36USP deubiquitinase suppresses DNA repair in host cells via deubiquitination of proliferating cell nuclear antigen. J Biol Chem. 2017;292:8472-8483 pubmed 出版商

Kim T, Park J, Kim M, Ahn Y. The role of CREB3L4 in the proliferation of prostate cancer cells. Sci Rep. 2017;7:45300 pubmed 出版商

Zollo M, Ahmed M, Ferrucci V, Salpietro V, Asadzadeh F, Carotenuto M, et al. PRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairment. Brain. 2017;140:940-952 pubmed 出版商

An L, Jiang Y, Ng H, Man E, Chen J, Khoo U, et al. Dual-utility NLS drives RNF169-dependent DNA damage responses. Proc Natl Acad Sci U S A. 2017;114:E2872-E2881 pubmed 出版商

Zhang Y, Li C, Yao G, Du L, Liu Y, Zheng X, et al. Deletion of Macrophage Mineralocorticoid Receptor Protects Hepatic Steatosis and Insulin Resistance Through ER?/HGF/Met Pathway. Diabetes. 2017;66:1535-1547 pubmed 出版商

Meijer B, Jang S, Guerrera I, Chhuon C, Lipecka J, Reisacher C, et al. Threonine eliminylation by bacterial phosphothreonine lyases rapidly causes cross-linking of mitogen-activated protein kinase (MAPK) in live cells. J Biol Chem. 2017;292:7784-7794 pubmed 出版商

Dupuis N, Laschet C, Franssen D, Szpakowska M, Gilissen J, Geubelle P, et al. Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes ?-Arrestin 2 Recruitment. Mol Pharmacol. 2017;91:595-608 pubmed 出版商

Marcassa E, Raimondi M, Anwar T, Eskelinen E, Myers M, Triolo G, et al. Calpain mobilizes Atg9/Bif-1 vesicles from Golgi stacks upon autophagy induction by thapsigargin. Biol Open. 2017;6:551-562 pubmed 出版商

Yamaji M, Jishage M, Meyer C, Suryawanshi H, Der E, Yamaji M, et al. DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs. Nature. 2017;543:568-572 pubmed 出版商

Xiang Y, Laurent B, Hsu C, Nachtergaele S, Lu Z, Sheng W, et al. RNA m6A methylation regulates the ultraviolet-induced DNA damage response. Nature. 2017;543:573-576 pubmed 出版商

Choudhary P, Armstrong E, Jorgensen C, Piotrowski M, Barthmes M, Torella R, et al. Discovery of Compounds that Positively Modulate the High Affinity Choline Transporter. Front Mol Neurosci. 2017;10:40 pubmed 出版商

Matsumoto Y, LaRose J, Kent O, Lim M, Changoor A, Zhang L, et al. RANKL coordinates multiple osteoclastogenic pathways by regulating expression of ubiquitin ligase RNF146. J Clin Invest. 2017;127:1303-1315 pubmed 出版商

Saitoh S, Maruyama T, Yako Y, Kajita M, Fujioka Y, Ohba Y, et al. Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cells. Proc Natl Acad Sci U S A. 2017;114:E2327-E2336 pubmed 出版商

Bagh M, Peng S, Chandra G, Zhang Z, Singh S, Pattabiraman N, et al. Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model. Nat Commun. 2017;8:14612 pubmed 出版商

Elwell C, Czudnochowski N, Von Dollen J, Johnson J, Nakagawa R, Mirrashidi K, et al. Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction. elife. 2017;6: pubmed 出版商

Ohno Y, Kamiyama N, Nakamichi S, Kihara A. PNPLA1 is a transacylase essential for the generation of the skin barrier lipid ω-O-acylceramide. Nat Commun. 2017;8:14610 pubmed 出版商

Yamamoto H, Tobisawa Y, Inubushi T, Irie F, Ohyama C, Yamaguchi Y. A mammalian homolog of the zebrafish transmembrane protein 2 (TMEM2) is the long-sought-after cell-surface hyaluronidase. J Biol Chem. 2017;292:7304-7313 pubmed 出版商

Jin X, Yang C, Fan P, Xiao J, Zhang W, Zhan S, et al. CDK5/FBW7-dependent ubiquitination and degradation of EZH2 inhibits pancreatic cancer cell migration and invasion. J Biol Chem. 2017;292:6269-6280 pubmed 出版商

Desrochers G, Cappadocia L, Lussier Price M, Ton A, Ayoubi R, Serohijos A, et al. Molecular basis of interactions between SH3 domain-containing proteins and the proline-rich region of the ubiquitin ligase Itch. J Biol Chem. 2017;292:6325-6338 pubmed 出版商

Pressey J, Mahadevan V, Khademullah C, Dargaei Z, Chevrier J, Ye W, et al. A kainate receptor subunit promotes the recycling of the neuron-specific K+-Cl- co-transporter KCC2 in hippocampal neurons. J Biol Chem. 2017;292:6190-6201 pubmed 出版商

Gallego García A, Iniesta A, Gonzalez D, Collier J, Padmanabhan S, Elías Arnanz M. Caulobacter crescentus CdnL is a non-essential RNA polymerase-binding protein whose depletion impairs normal growth and rRNA transcription. Sci Rep. 2017;7:43240 pubmed 出版商

Mutazono M, Morita M, Tsukahara C, Chinen M, Nishioka S, Yumikake T, et al. The intron in centromeric noncoding RNA facilitates RNAi-mediated formation of heterochromatin. PLoS Genet. 2017;13:e1006606 pubmed 出版商

Oakley R, Busillo J, Cidlowski J. Cross-talk between the glucocorticoid receptor and MyoD family inhibitor domain-containing protein provides a new mechanism for generating tissue-specific responses to glucocorticoids. J Biol Chem. 2017;292:5825-5844 pubmed 出版商

Singh V, Katta S, Kumar S. WD-repeat protein WDR13 is a novel transcriptional regulator of c-Jun and modulates intestinal homeostasis in mice. BMC Cancer. 2017;17:148 pubmed 出版商

Chen C, Zhang X. IRE1α-XBP1 pathway promotes melanoma progression by regulating IL-6/STAT3 signaling. J Transl Med. 2017;15:42 pubmed 出版商

Xu Z, Greenblatt M, Yan G, Feng H, Sun J, Lotinun S, et al. SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts. Nat Commun. 2017;8:14570 pubmed 出版商

Rai R, Hu C, Broton C, Chen Y, Lei M, Chang S. NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres. Mol Cell. 2017;65:801-817.e4 pubmed 出版商

Kozaki T, Komano J, Kanbayashi D, Takahama M, Misawa T, Satoh T, et al. Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response. Proc Natl Acad Sci U S A. 2017;114:2681-2686 pubmed 出版商

Li Z, Ivanov A, Su R, Gonzalez Pecchi V, Qi Q, Liu S, et al. The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies. Nat Commun. 2017;8:14356 pubmed 出版商

Wu Y, Wang Y, Lin Y, Liu Y, Wang Y, Jia J, et al. Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation. Nat Commun. 2017;8:14228 pubmed 出版商

Zusso M, Mercanti G, Belluti F, Di Martino R, Pagetta A, Marinelli C, et al. Phenolic 1,3-diketones attenuate lipopolysaccharide-induced inflammatory response by an alternative magnesium-mediated mechanism. Br J Pharmacol. 2017;174:1090-1103 pubmed 出版商

Shaw D, Wang X, Brown L, Chávez A, Reif K, Smith A, et al. Infection-derived lipids elicit an immune deficiency circuit in arthropods. Nat Commun. 2017;8:14401 pubmed 出版商

Bresson S, Tuck A, Staneva D, Tollervey D. Nuclear RNA Decay Pathways Aid Rapid Remodeling of Gene Expression in Yeast. Mol Cell. 2017;65:787-800.e5 pubmed 出版商

Augustine T, Chaudhary P, Gupta K, Islam S, Ghosh P, Santra M, et al. Cyclin F/FBXO1 Interacts with HIV-1 Viral Infectivity Factor (Vif) and Restricts Progeny Virion Infectivity by Ubiquitination and Proteasomal Degradation of Vif Protein through SCFcyclin F E3 Ligase Machinery. J Biol Chem. 2017;292:5349-5363 pubmed 出版商

Li X, Gao M, Choi J, Kim B, Zhou M, Chen Z, et al. Clustered, Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9-coupled Affinity Purification/Mass Spectrometry Analysis Revealed a Novel Role of Neurofibromin in mTOR Signaling. Mol Cell Proteomics. 2017;16:594-607 pubmed 出版商

Shah M, Smolko C, Kinicki S, Chapman Z, Brautigan D, Janes K. Profiling Subcellular Protein Phosphatase Responses to Coxsackievirus B3 Infection of Cardiomyocytes. Mol Cell Proteomics. 2017;16:S244-S262 pubmed 出版商

Wang L, Fu B, Li W, Patil G, Liu L, Dorf M, et al. Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction. Nat Commun. 2017;8:13876 pubmed 出版商

Goth C, Tuhkanen H, Khan H, Lackman J, Wang S, Narimatsu Y, et al. Site-specific O-Glycosylation by Polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-transferase T2) Co-regulates β1-Adrenergic Receptor N-terminal Cleavage. J Biol Chem. 2017;292:4714-4726 pubmed 出版商

Xiong X, Liu Y, Mei Y, Peng J, Wang Z, Kong B, et al. Novel Protective Role of Myeloid Differentiation 1 in Pathological Cardiac Remodelling. Sci Rep. 2017;7:41857 pubmed 出版商

Lovric S, Gonçalves S, Gee H, Oskouian B, Srinivas H, Choi W, et al. Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency. J Clin Invest. 2017;127:912-928 pubmed 出版商

Qi H, Chu V, Wu N, Chen Z, Truong S, Brar G, et al. Systematic identification of anti-interferon function on hepatitis C virus genome reveals p7 as an immune evasion protein. Proc Natl Acad Sci U S A. 2017;114:2018-2023 pubmed 出版商

Pauty J, Couturier A, Rodrigue A, Caron M, Coulombe Y, Dellaire G, et al. Cancer-causing mutations in the tumor suppressor PALB2 reveal a novel cancer mechanism using a hidden nuclear export signal in the WD40 repeat motif. Nucleic Acids Res. 2017;45:2644-2657 pubmed 出版商

Nounamo B, Li Y, O Byrne P, Kearney A, Khan A, Liu J. An interaction domain in human SAMD9 is essential for myxoma virus host-range determinant M062 antagonism of host anti-viral function. Virology. 2017;503:94-102 pubmed 出版商

Dominguez Brauer C, Khatun R, Elia A, Thu K, Ramachandran P, Baniasadi S, et al. E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling. Proc Natl Acad Sci U S A. 2017;114:E1148-E1157 pubmed 出版商

Biehs R, Steinlage M, Barton O, Juhasz S, Künzel J, Spies J, et al. DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination. Mol Cell. 2017;65:671-684.e5 pubmed 出版商

Amen A, Ruiz Garzon C, Shi J, Subramanian M, Pham D, Meffert M. A Rapid Induction Mechanism for Lin28a in Trophic Responses. Mol Cell. 2017;65:490-503.e7 pubmed 出版商

Huang Q, Merriman C, Zhang H, Fu D. Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells. J Biol Chem. 2017;292:4034-4043 pubmed 出版商

Youn J, Friesen H, Nguyen Ba A, Liang W, Messier V, Cox M, et al. Functional Analysis of Kinases and Transcription Factors in Saccharomyces cerevisiae Using an Integrated Overexpression Library. G3 (Bethesda). 2017;7:911-921 pubmed 出版商

Young C, Hillyer C, Hokamp K, Fitzpatrick D, Konstantinov N, Welty J, et al. Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast. BMC Genomics. 2017;18:107 pubmed 出版商

Keszei A, Sicheri F. Mechanism of catalysis, E2 recognition, and autoinhibition for the IpaH family of bacterial E3 ubiquitin ligases. Proc Natl Acad Sci U S A. 2017;114:1311-1316 pubmed 出版商

Hostettler L, Grundy L, Käser Pébernard S, Wicky C, Schafer W, Glauser D. The Bright Fluorescent Protein mNeonGreen Facilitates Protein Expression Analysis In Vivo. G3 (Bethesda). 2017;7:607-615 pubmed 出版商

Arthur L, Chung J, Jankirama P, Keefer K, Kolotilin I, Pavlovic Djuranovic S, et al. Rapid generation of hypomorphic mutations. Nat Commun. 2017;8:14112 pubmed 出版商

Shibata Y, Tokunaga F, Goto E, Komatsu G, Gohda J, Saeki Y, et al. HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains. PLoS Pathog. 2017;13:e1006162 pubmed 出版商

Asensio Juan E, Fueyo R, PAPPA S, Iacobucci S, Badosa C, Lois S, et al. The histone demethylase PHF8 is a molecular safeguard of the IFNγ response. Nucleic Acids Res. 2017;45:3800-3811 pubmed 出版商

Chen R, Zhao X, Wang Y, Xie Y, Liu J. Hepatitis B virus X protein is capable of down-regulating protein level of host antiviral protein APOBEC3G. Sci Rep. 2017;7:40783 pubmed 出版商

Pirone L, Xolalpa W, Sigurðsson J, Ramirez J, Pérez C, Gonzalez M, et al. A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation. Sci Rep. 2017;7:40756 pubmed 出版商

Zhang Y, Fang M, Song Y, Ren J, Fang J, Wang X. Brother of Regulator of Imprinted Sites (BORIS) suppresses apoptosis in colorectal cancer. Sci Rep. 2017;7:40786 pubmed 出版商

Gustavsson M, Wang L, van Gils N, Stephens B, Zhang P, Schall T, et al. Structural basis of ligand interaction with atypical chemokine receptor 3. Nat Commun. 2017;8:14135 pubmed 出版商

Lee H, Min K, Yi J, Shi H, Chang W, Jackson L, et al. A Phosphoproteomic Screen Identifies a Guanine Nucleotide Exchange Factor for Rab3A Protein as a Mitogen-activated Protein (MAP) Kinase Phosphatase-5-regulated MAP Kinase Target in Interleukin 6 (IL-6) Secretion and Myogenesis. J Biol Chem. 2017;292:3581-3590 pubmed 出版商

Zhang L, Peng S, Dai X, Gan W, Nie X, Wei W, et al. Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells. Cancer Lett. 2017;390:11-20 pubmed 出版商

Gao S, Geng C, Song T, Lin X, Liu J, Cai Z, et al. Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase. J Biol Chem. 2017;292:3683-3691 pubmed 出版商

Fiskin E, Bhogaraju S, Herhaus L, Kalayil S, Hahn M, Dikic I. Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA. Nat Commun. 2017;8:14004 pubmed 出版商

Safina A, Cheney P, Pal M, Brodsky L, Ivanov A, Kirsanov K, et al. FACT is a sensor of DNA torsional stress in eukaryotic cells. Nucleic Acids Res. 2017;45:1925-1945 pubmed 出版商

Ly N, Cyert M. Calcineurin, the Ca2+-dependent phosphatase, regulates Rga2, a Cdc42 GTPase-activating protein, to modulate pheromone signaling. Mol Biol Cell. 2017;28:576-586 pubmed 出版商

Celona B, Dollen J, Vatsavayai S, Kashima R, Johnson J, Tang A, et al. Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106. elife. 2017;6: pubmed 出版商

Juszkiewicz S, Hegde R. Initiation of Quality Control during Poly(A) Translation Requires Site-Specific Ribosome Ubiquitination. Mol Cell. 2017;65:743-750.e4 pubmed 出版商

Liu X, Gao Y, Ye H, Gerrin S, Ma F, Wu Y, et al. Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer. Nucleic Acids Res. 2017;45:3738-3751 pubmed 出版商

Wang W, Xiao F, Wan P, Pan P, Zhang Y, Liu F, et al. EV71 3D Protein Binds with NLRP3 and Enhances the Assembly of Inflammasome Complex. PLoS Pathog. 2017;13:e1006123 pubmed 出版商

Moniz L, Surinova S, Ghazaly E, Velasco L, Haider S, Rodríguez Prados J, et al. Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate. Sci Rep. 2017;7:39985 pubmed 出版商

Yuan W, Guo S, Gao J, Zhong M, Yan G, Wu W, et al. General Control Nonderepressible 2 (GCN2) Kinase Inhibits Target of Rapamycin Complex 1 in Response to Amino Acid Starvation in Saccharomyces cerevisiae. J Biol Chem. 2017;292:2660-2669 pubmed 出版商

Shimizu K, Fukushima H, Ogura K, Lien E, Nihira N, Zhang J, et al. The SCF?-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis. Sci Signal. 2017;10: pubmed 出版商

Shi D, Shi H, Sun D, Chen J, Zhang X, Wang X, et al. Nucleocapsid Interacts with NPM1 and Protects it from Proteolytic Cleavage, Enhancing Cell Survival, and is Involved in PEDV Growth. Sci Rep. 2017;7:39700 pubmed 出版商

Askew E, Bai S, Parris A, Minges J, Wilson E. Androgen receptor regulation by histone methyltransferase Suppressor of variegation 3-9 homolog 2 and Melanoma antigen-A11. Mol Cell Endocrinol. 2017;443:42-51 pubmed 出版商

Zhou F, Huang D, Li Y, Hu G, Rao H, Lu Q, et al. Nek2A/SuFu feedback loop regulates Gli-mediated Hedgehog signaling pathway. Int J Oncol. 2017;50:373-380 pubmed 出版商

Tsuji T, Kurokawa Y, Chiche J, Pouysségur J, Sato H, Fukuzawa H, et al. Dissecting the Process of Activation of Cancer-promoting Zinc-requiring Ectoenzymes by Zinc Metalation Mediated by ZNT Transporters. J Biol Chem. 2017;292:2159-2173 pubmed 出版商

Xu X, Han L, Zhao G, Xue S, Gao Y, Xiao J, et al. LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis. J Exp Med. 2017;214:209-226 pubmed 出版商

Harms F, Girisha K, Hardigan A, Kortüm F, Shukla A, Alawi M, et al. Mutations in EBF3 Disturb Transcriptional Profiles and Cause Intellectual Disability, Ataxia, and Facial Dysmorphism. Am J Hum Genet. 2017;100:117-127 pubmed 出版商

Wei Y, Chiang W, Sumpter R, Mishra P, Levine B. Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor. Cell. 2017;168:224-238.e10 pubmed 出版商

Li C, Luo X, Zhao S, Siu G, Liang Y, Chan H, et al. COPI-TRAPPII activates Rab18 and regulates its lipid droplet association. EMBO J. 2017;36:441-457 pubmed 出版商

Morii M, Kubota S, Honda T, Yuki R, Morinaga T, Kuga T, et al. Src Acts as an Effector for Ku70-dependent Suppression of Apoptosis through Phosphorylation of Ku70 at Tyr-530. J Biol Chem. 2017;292:1648-1665 pubmed 出版商

Chen J, Cai T, Zheng C, Lin X, Wang G, Liao S, et al. MicroRNA-202 maintains spermatogonial stem cells by inhibiting cell cycle regulators and RNA binding proteins. Nucleic Acids Res. 2017;45:4142-4157 pubmed 出版商

Roychoudhury S, Nath S, Song H, Hegde M, Bellot L, Mantha A, et al. Human Apurinic/Apyrimidinic Endonuclease (APE1) Is Acetylated at DNA Damage Sites in Chromatin, and Acetylation Modulates Its DNA Repair Activity. Mol Cell Biol. 2017;37: pubmed 出版商

Fettweis G, Di Valentin E, L homme L, Lassence C, Dequiedt F, Fillet M, et al. RIP3 antagonizes a TSC2-mediated pro-survival pathway in glioblastoma cell death. Biochim Biophys Acta Mol Cell Res. 2017;1864:113-124 pubmed 出版商

Chen Y, Liu H, Zhang H, Sun C, Hu Z, Tian Q, et al. And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance. Nucleic Acids Res. 2017;45:2516-2530 pubmed 出版商

Shkreta L, Blanchette M, Toutant J, Wilhelm E, Bell B, Story B, et al. Modulation of the splicing regulatory function of SRSF10 by a novel compound that impairs HIV-1 replication. Nucleic Acids Res. 2017;45:4051-4067 pubmed 出版商

Ali T, Kruger M, Bhuju S, Jarek M, Bartkuhn M, Renkawitz R. Chromatin binding of Gcn5 in Drosophila is largely mediated by CP190. Nucleic Acids Res. 2017;45:2384-2395 pubmed 出版商

Kung Y, Hung C, Chien K, Shih S. Control of the negative IRES trans-acting factor KHSRP by ubiquitination. Nucleic Acids Res. 2017;45:271-287 pubmed 出版商

Yasuda H, Oh C, Chen D, de Crombrugghe B, Kim J. A Novel Regulatory Mechanism of Type II Collagen Expression via a SOX9-dependent Enhancer in Intron 6. J Biol Chem. 2017;292:528-538 pubmed 出版商

Kim W, Khan S, Gvozdenovic Jeremic J, Kim Y, Dahlman J, Kim H, et al. Hippo signaling interactions with Wnt/?-catenin and Notch signaling repress liver tumorigenesis. J Clin Invest. 2017;127:137-152 pubmed 出版商

Gu P, Wang Y, Bisht K, Wu L, Kukova L, Smith E, et al. Pot1 OB-fold mutations unleash telomere instability to initiate tumorigenesis. Oncogene. 2017;36:1939-1951 pubmed 出版商

Kayama K, Watanabe S, Takafuji T, Tsuji T, Hironaka K, Matsumoto M, et al. GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis. EMBO Rep. 2017;18:123-137 pubmed 出版商

Hung P, Chen B, George R, Liberman C, Morales A, Colon Ortiz P, et al. Deficiency of XLF and PAXX prevents DNA double-strand break repair by non-homologous end joining in lymphocytes. Cell Cycle. 2017;16:286-295 pubmed 出版商

Zhu P, Liang L, Shao X, Luo W, Jiang S, Zhao Q, et al. Host Cellular Protein TRAPPC6AΔ Interacts with Influenza A Virus M2 Protein and Regulates Viral Propagation by Modulating M2 Trafficking. J Virol. 2017;91: pubmed 出版商

Pan Y, Wang S, Su B, Zhou F, Xu T, Zhang R, et al. Stat3 contributes to cancer progression by regulating Jab1/Csn5 expression. Oncogene. 2017;36:1069-1079 pubmed 出版商

Liu T, Zhao M, Liu J, He Z, Zhang Y, You H, et al. Tumor suppressor bromodomain-containing protein 7 cooperates with Smads to promote transforming growth factor-β responses. Oncogene. 2017;36:362-372 pubmed 出版商

Yu X, Jiang L, Wu R, Meng X, Zhang A, Li N, et al. The Core Subunit of A Chromatin-Remodeling Complex, ZmCHB101, Plays Essential Roles in Maize Growth and Development. Sci Rep. 2016;6:38504 pubmed 出版商

Jaber N, Mohd Naim N, Wang Z, Deleon J, Kim S, Zhong H, et al. Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus. J Cell Sci. 2016;129:4424-4435 pubmed

Lu H, Bhoopatiraju S, Wang H, Schmitz N, Wang X, Freeman M, et al. Loss of UHRF2 expression is associated with human neoplasia, promoter hypermethylation, decreased 5-hydroxymethylcytosine, and high proliferative activity. Oncotarget. 2016;7:76047-76061 pubmed 出版商

Yang H, Zhao X, Zhao L, Liu L, Li J, Jia W, et al. PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma. Oncotarget. 2016;7:72131-72147 pubmed 出版商

Zavorka M, Connelly C, Grosely R, MacDonald R. Inhibition of insulin-like growth factor II (IGF-II)-dependent cell growth by multidentate pentamannosyl 6-phosphate-based ligands targeting the mannose 6-phosphate/IGF-II receptor. Oncotarget. 2016;7:62386-62410 pubmed 出版商

Ow J, Palanichamy Kala M, Rao V, Choi M, Bharathy N, Taneja R. G9a inhibits MEF2C activity to control sarcomere assembly. Sci Rep. 2016;6:34163 pubmed 出版商

Kawashima S, Chen Z, Aoi Y, Patgiri A, Kobayashi Y, Nurse P, et al. Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis. Cell. 2016;167:512-524.e14 pubmed 出版商

You D, Zhao H, Wang Y, Jiao Y, Lu M, Yan S. Acetylation Enhances the Promoting Role of AIB1 in Breast Cancer Cell Proliferation. Mol Cells. 2016;39:663-8 pubmed 出版商

Depaolo J, Wang Z, Guo J, Zhang G, Qian C, Zhang H, et al. Acetylation of androgen receptor by ARD1 promotes dissociation from HSP90 complex and prostate tumorigenesis. Oncotarget. 2016;7:71417-71428 pubmed 出版商

Neubauer H, Pham D, Zebol J, Moretti P, Peterson A, Leclercq T, et al. An oncogenic role for sphingosine kinase 2. Oncotarget. 2016;7:64886-64899 pubmed 出版商

Meghini F, Martins T, Tait X, Fujimitsu K, Yamano H, Glover D, et al. Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit. Nat Commun. 2016;7:12607 pubmed 出版商

Duan Y, Huo D, Gao J, Wu H, Ye Z, Liu Z, et al. Ubiquitin ligase RNF20/40 facilitates spindle assembly and promotes breast carcinogenesis through stabilizing motor protein Eg5. Nat Commun. 2016;7:12648 pubmed 出版商

Romani B, Kamali Jamil R, Hamidi Fard M, Rahimi P, Momen S, Aghasadeghi M, et al. HIV-1 Vpr reactivates latent HIV-1 provirus by inducing depletion of class I HDACs on chromatin. Sci Rep. 2016;6:31924 pubmed 出版商

Perez C, Pérez Zúñiga F, Garrido F, Reytor E, Portillo F, Pajares M. The Oncogene PDRG1 Is an Interaction Target of Methionine Adenosyltransferases. PLoS ONE. 2016;11:e0161672 pubmed 出版商

Liu Z, Ning G, Xu R, Cao Y, Meng A, Wang Q. Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation. Nat Commun. 2016;7:12603 pubmed 出版商

Sun L, Fan G, Shan P, Qiu X, Dong S, Liao L, et al. Regulation of energy homeostasis by the ubiquitin-independent REG? proteasome. Nat Commun. 2016;7:12497 pubmed 出版商

Li Q, Zhu Y, Hou L, Wang J, Hu G, Fang X, et al. C23 promotes tumorigenesis via suppressing p53 activity. Oncotarget. 2016;7:58274-58285 pubmed 出版商

Li X, Li X, Li M, Yan Y, Liu X, Li L. Dual Function of NAC072 in ABF3-Mediated ABA-Responsive Gene Regulation in Arabidopsis. Front Plant Sci. 2016;7:1075 pubmed 出版商

Meng R, Qin Q, Xiong Y, Wang Y, Zheng J, Zhao Y, et al. NHERF1, a novel GPER associated protein, increases stability and activation of GPER in ER-positive breast cancer. Oncotarget. 2016;7:54983-54997 pubmed 出版商

Fernando R, Cotter L, Perrin Tricaud C, Berthelot J, Bartolami S, Pereira J, et al. Optimal myelin elongation relies on YAP activation by axonal growth and inhibition by Crb3/Hippo pathway. Nat Commun. 2016;7:12186 pubmed 出版商

Liu X, Ehmed E, Li B, Dou J, Qiao X, Jiang W, et al. Breast cancer metastasis suppressor 1 modulates SIRT1-dependent p53 deacetylation through interacting with DBC1. Am J Cancer Res. 2016;6:1441-9 pubmed

Jang H, Lee G, Selby C, Lee G, Jeon Y, Lee J, et al. SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding. Nat Commun. 2016;7:12180 pubmed 出版商

Wei C, Cheng J, Zhou B, Zhu L, Khan M, He T, et al. Tripartite motif containing 28 (TRIM28) promotes breast cancer metastasis by stabilizing TWIST1 protein. Sci Rep. 2016;6:29822 pubmed 出版商

Li P, Rivera Cancel G, Kinch L, Salomon D, Tomchick D, Grishin N, et al. Bile salt receptor complex activates a pathogenic type III secretion system. elife. 2016;5: pubmed 出版商

Tirumuru N, Zhao B, Lu W, Lu Z, He C, Wu L. N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression. elife. 2016;5: pubmed 出版商

Roshanbin S, Lindberg F, Lekholm E, Eriksson M, Perland E, Åhlund J, et al. Histological characterization of orphan transporter MCT14 (SLC16A14) shows abundant expression in mouse CNS and kidney. BMC Neurosci. 2016;17:43 pubmed 出版商

Van Haute L, Dietmann S, Kremer L, Hussain S, Pearce S, Powell C, et al. Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3. Nat Commun. 2016;7:12039 pubmed 出版商

Gong J, Körner R, Gaitanos L, Klein R. Exosomes mediate cell contact-independent ephrin-Eph signaling during axon guidance. J Cell Biol. 2016;214:35-44 pubmed 出版商

Walport L, Hopkinson R, Chowdhury R, Schiller R, Ge W, Kawamura A, et al. Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases. Nat Commun. 2016;7:11974 pubmed 出版商

Sasai K, Katayama H, Hawke D, Sen S. Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex. PLoS ONE. 2016;11:e0157305 pubmed 出版商

Ramakrishnan S, Pokhrel S, Palani S, Pflueger C, Parnell T, Cairns B, et al. Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription. Nat Commun. 2016;7:11949 pubmed 出版商

Kathania M, Khare P, Zeng M, Cantarel B, Zhang H, Ueno H, et al. Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-?t ubiquitination. Nat Immunol. 2016;17:997-1004 pubmed 出版商

Yokoi N, Fukata Y, Sekiya A, Murakami T, Kobayashi K, Fukata M. Identification of PSD-95 Depalmitoylating Enzymes. J Neurosci. 2016;36:6431-44 pubmed 出版商

Kuramoto K, Wang N, Fan Y, Zhang W, Schoenen F, Frankowski K, et al. Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids. Autophagy. 2016;12:1460-71 pubmed 出版商

Qiao Y, Qian Y, Wang J, Tang X. Melanoma cell adhesion molecule stimulates yes-associated protein transcription by enhancing CREB activity via c-Jun/c-Fos in hepatocellular carcinoma cells. Oncol Lett. 2016;11:3702-3708 pubmed

Bento C, Ashkenazi A, Jimenez Sanchez M, Rubinsztein D. The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway. Nat Commun. 2016;7:11803 pubmed 出版商

Wang J, Farris A, Xu K, Wang P, Zhang X, Duong D, et al. GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesis. Nat Commun. 2016;7:11795 pubmed 出版商

Zhang Y, Huang L, Fu H, Smith O, Lin C, Utani K, et al. A replicator-specific binding protein essential for site-specific initiation of DNA replication in mammalian cells. Nat Commun. 2016;7:11748 pubmed 出版商

Suzuki K, Tsunoda H, Omiya R, Matoba K, Baba T, Suzuki S, et al. Structure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies. PLoS ONE. 2016;11:e0156719 pubmed 出版商

Wilkins J, Zheng Y, Yu J, Liang C, Liu S. Nonhuman Primate IFITM Proteins Are Potent Inhibitors of HIV and SIV. PLoS ONE. 2016;11:e0156739 pubmed 出版商

Zhang Y, Liu H, Yi R, Yan T, He Y, Zhao Y, et al. Hepatitis B virus whole-X and X protein play distinct roles in HBV-related hepatocellular carcinoma progression. J Exp Clin Cancer Res. 2016;35:87 pubmed 出版商

Ji Y, Zhang P, Zhang X, Zhao Y, Deng K, Jiang X, et al. The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling. Nat Commun. 2016;7:11267 pubmed 出版商

Brunk K, Zhu M, Bärenz F, Kratz A, Haselmann Weiss U, Antony C, et al. Cep78 is a new centriolar protein involved in Plk4-induced centriole overduplication. J Cell Sci. 2016;129:2713-8 pubmed 出版商

Tuschl K, Meyer E, Valdivia L, Zhao N, Dadswell C, Abdul Sada A, et al. Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia. Nat Commun. 2016;7:11601 pubmed 出版商

Rao V, Ow J, Shankar S, Bharathy N, Manikandan J, Wang Y, et al. G9a promotes proliferation and inhibits cell cycle exit during myogenic differentiation. Nucleic Acids Res. 2016;44:8129-43 pubmed 出版商

Tribollet V, Barenton B, Kroiss A, Vincent S, Zhang L, Forcet C, et al. miR-135a Inhibits the Invasion of Cancer Cells via Suppression of ERR?. PLoS ONE. 2016;11:e0156445 pubmed 出版商

Nishito Y, Tsuji N, Fujishiro H, Takeda T, Yamazaki T, Teranishi F, et al. Direct Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter. J Biol Chem. 2016;291:14773-87 pubmed 出版商

Zhang L, Luga V, Armitage S, Musiol M, Won A, Yip C, et al. A lateral signalling pathway coordinates shape volatility during cell migration. Nat Commun. 2016;7:11714 pubmed 出版商

Lee Y, Lee J, Bae Y, Lee B, Kim E, Cho C, et al. Suppression of 14-3-3γ-mediated surface expression of ANO1 inhibits cancer progression of glioblastoma cells. Sci Rep. 2016;6:26413 pubmed 出版商

Bao J, Zheng L, Zhang Q, Li X, Zhang X, Li Z, et al. Deacetylation of TFEB promotes fibrillar A? degradation by upregulating lysosomal biogenesis in microglia. Protein Cell. 2016;7:417-33 pubmed 出版商

Ni T, Kuperwasser C. Premature polyadenylation of MAGI3 produces a dominantly-acting oncogene in human breast cancer. elife. 2016;5: pubmed 出版商

Park A, Yun T, Vigant F, Pernet O, Won S, Dawes B, et al. Nipah Virus C Protein Recruits Tsg101 to Promote the Efficient Release of Virus in an ESCRT-Dependent Pathway. PLoS Pathog. 2016;12:e1005659 pubmed 出版商

Zeng L, Cai C, Li S, Wang W, Li Y, Chen J, et al. Essential Roles of Cyclin Y-Like 1 and Cyclin Y in Dividing Wnt-Responsive Mammary Stem/Progenitor Cells. PLoS Genet. 2016;12:e1006055 pubmed 出版商

Barry W, Thummel C. The Drosophila HNF4 nuclear receptor promotes glucose-stimulated insulin secretion and mitochondrial function in adults. elife. 2016;5: pubmed 出版商

Fusté N, Fernández Hernández R, Cemeli T, Mirantes C, Pedraza N, Rafel M, et al. Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin. Nat Commun. 2016;7:11581 pubmed 出版商

Han L, Schubert C, Köhler J, Schemionek M, Isfort S, Brummendorf T, et al. Calreticulin-mutant proteins induce megakaryocytic signaling to transform hematopoietic cells and undergo accelerated degradation and Golgi-mediated secretion. J Hematol Oncol. 2016;9:45 pubmed 出版商

Alarcón V, Hernández S, Rubio L, Alvarez F, Flores Y, Varas Godoy M, et al. The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state. Sci Rep. 2016;6:25901 pubmed 出版商

Thakur P, Gantasala N, Choudhary E, Singh N, Abdin M, Agarwal N. The preprotein translocase YidC controls respiratory metabolism in Mycobacterium tuberculosis. Sci Rep. 2016;6:24998 pubmed 出版商

Humoud M, Doyle N, Royall E, Willcocks M, Sorgeloos F, van Kuppeveld F, et al. Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage. J Virol. 2016;90:6489-6501 pubmed 出版商

Wang L, Lee K, Malonis R, SANCHEZ I, Dynlacht B. Tethering of an E3 ligase by PCM1 regulates the abundance of centrosomal KIAA0586/Talpid3 and promotes ciliogenesis. elife. 2016;5: pubmed 出版商

Yang E, Tacchelly Benites O, Wang Z, Randall M, Tian A, Benchabane H, et al. Wnt pathway activation by ADP-ribosylation. Nat Commun. 2016;7:11430 pubmed 出版商

Lin X, Niu D, Hu Z, Kim D, Jin Y, Cai B, et al. An Arabidopsis SUMO E3 Ligase, SIZ1, Negatively Regulates Photomorphogenesis by Promoting COP1 Activity. PLoS Genet. 2016;12:e1006016 pubmed 出版商

Strappazzon F, Di Rita A, Cianfanelli V, D Orazio M, Nazio F, Fimia G, et al. Prosurvival AMBRA1 turns into a proapoptotic BH3-like protein during mitochondrial apoptosis. Autophagy. 2016;12:963-75 pubmed 出版商

Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed 出版商

De Boeck M, Cui C, Mulder A, Jost C, Ikeno S, Ten Dijke P. Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model. Sci Rep. 2016;6:24968 pubmed 出版商

Kim T, Shin S, Janknecht R. ETS transcription factor ERG cooperates with histone demethylase KDM4A. Oncol Rep. 2016;35:3679-88 pubmed 出版商

Niu D, Lii Y, Chellappan P, Lei L, Peralta K, Jiang C, et al. miRNA863-3p sequentially targets negative immune regulator ARLPKs and positive regulator SERRATE upon bacterial infection. Nat Commun. 2016;7:11324 pubmed 出版商

Chen N, Zhou L, Gane P, Opp S, Ball N, Nicastro G, et al. HIV-1 capsid is involved in post-nuclear entry steps. Retrovirology. 2016;13:28 pubmed 出版商

Zhang Q, Gao M, Zhang Y, Song Y, Cheng H, Zhou R. The germline-enriched Ppp1r36 promotes autophagy. Sci Rep. 2016;6:24609 pubmed 出版商

Okumura F, Uematsu K, Byrne S, Hirano M, Joo Okumura A, Nishikimi A, et al. Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor ?. Mol Cell Biol. 2016;36:1803-17 pubmed 出版商

Onyango D, Howard S, Neherin K, Yanez D, Stark J. Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination. Nucleic Acids Res. 2016;44:5702-16 pubmed 出版商

Li Z, Ji X, Wang W, Liu J, Liang X, Wu H, et al. Ammonia Induces Autophagy through Dopamine Receptor D3 and MTOR. PLoS ONE. 2016;11:e0153526 pubmed 出版商

Cantarino N, Fernández Figueras M, Valero V, Musulen E, Malinverni R, Granada I, et al. A cellular model reflecting the phenotypic heterogeneity of mutant HRAS driven squamous cell carcinoma. Int J Cancer. 2016;139:1106-16 pubmed 出版商

Keyvani Chahi A, Martin C, Jones N. Nephrin Suppresses Hippo Signaling through the Adaptor Proteins Nck and WTIP. J Biol Chem. 2016;291:12799-808 pubmed 出版商

Lian Y, Yuan J, Cui Q, Feng Q, Xu M, Bei J, et al. Upregulation of KLHDC4 Predicts a Poor Prognosis in Human Nasopharyngeal Carcinoma. PLoS ONE. 2016;11:e0152820 pubmed 出版商

Zhao K, Zhang M, Zhang L, Wang P, Song G, Liu B, et al. Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response. Sci Rep. 2016;6:23771 pubmed 出版商

Chatelle C, Hövermann D, Muller A, Wagner H, Weber W, Radziwill G. Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors. Sci Rep. 2016;6:23713 pubmed 出版商

Brown J, Petersen A, Zhong L, Himelright M, Murphy J, Walikonis R, et al. Bidirectional regulation of synaptic transmission by BRAG1/IQSEC2 and its requirement in long-term depression. Nat Commun. 2016;7:11080 pubmed 出版商

McKenzie C, Bassi Z, Debski J, Gottardo M, Callaini G, Dadlez M, et al. Cross-regulation between Aurora B and Citron kinase controls midbody architecture in cytokinesis. Open Biol. 2016;6: pubmed 出版商

Young H, Zhao J, Barker J, Guan Z, Valdivia R, Zhou P. Discovery of the Elusive UDP-Diacylglucosamine Hydrolase in the Lipid A Biosynthetic Pathway in Chlamydia trachomatis. MBio. 2016;7:e00090 pubmed 出版商

Wu J, Ivanov A, Fisher P, Fu Z. Polo-like kinase 1 induces epithelial-to-mesenchymal transition and promotes epithelial cell motility by activating CRAF/ERK signaling. elife. 2016;5: pubmed 出版商

Liu X, Xiao Z, Han L, Zhang J, Lee S, Wang W, et al. LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress. Nat Cell Biol. 2016;18:431-42 pubmed 出版商

Salzman D, Nakamura K, Nallur S, Dookwah M, Metheetrairut C, Slack F, et al. miR-34 activity is modulated through 5'-end phosphorylation in response to DNA damage. Nat Commun. 2016;7:10954 pubmed 出版商

Rasheedi S, Shun M, Serrao E, Sowd G, Qian J, Hao C, et al. The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes. J Biol Chem. 2016;291:11809-19 pubmed 出版商

Hildebrand E, Biggins S. Regulation of Budding Yeast CENP-A levels Prevents Misincorporation at Promoter Nucleosomes and Transcriptional Defects. PLoS Genet. 2016;12:e1005930 pubmed 出版商

Christensen D, Ejlerskov P, Rasmussen I, Vilhardt F. Reciprocal signals between microglia and neurons regulate α-synuclein secretion by exophagy through a neuronal cJUN-N-terminal kinase-signaling axis. J Neuroinflammation. 2016;13:59 pubmed 出版商

Frej A, Clark J, Le Roy C, Lilla S, Thomason P, Otto G, et al. The Inositol-3-Phosphate Synthase Biosynthetic Enzyme Has Distinct Catalytic and Metabolic Roles. Mol Cell Biol. 2016;36:1464-79 pubmed 出版商

Wollscheid H, Biancospino M, He F, Magistrati E, Molteni E, Lupia M, et al. Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain. Nat Struct Mol Biol. 2016;23:300-308 pubmed 出版商

Du Z, Li L, Huang X, Jin J, Huang S, Zhang Q, et al. The epigenetic modifier CHD5 functions as a novel tumor suppressor for renal cell carcinoma and is predominantly inactivated by promoter CpG methylation. Oncotarget. 2016;7:21618-30 pubmed 出版商

Rai R, Chen Y, Lei M, Chang S. TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions. Nat Commun. 2016;7:10881 pubmed 出版商

Gu X, Mao X, Lussier M, Hutchison M, Zhou L, Hamra F, et al. GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons. Nat Commun. 2016;7:10873 pubmed 出版商

Woo J, Srikanth S, Nishi M, Ping P, Takeshima H, Gwack Y. Junctophilin-4, a component of the endoplasmic reticulum-plasma membrane junctions, regulates Ca2+ dynamics in T cells. Proc Natl Acad Sci U S A. 2016;113:2762-7 pubmed 出版商

Sadasivam D, Huang D. Maintenance of Tissue Pluripotency by Epigenetic Factors Acting at Multiple Levels. PLoS Genet. 2016;12:e1005897 pubmed 出版商

Weiher H, Pircher H, Jansen Dürr P, Hegenbarth S, Knolle P, Grunau S, et al. A monoclonal antibody raised against bacterially expressed MPV17 sequences shows peroxisomal, endosomal and lysosomal localisation in U2OS cells. BMC Res Notes. 2016;9:128 pubmed 出版商

Hyrsová L, Smutny T, Carazo A, Moravcik S, Mandíková J, Trejtnar F, et al. The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator. Br J Pharmacol. 2016;173:1703-15 pubmed 出版商

Liu N, Avramova Z. Molecular mechanism of the priming by jasmonic acid of specific dehydration stress response genes in Arabidopsis. Epigenetics Chromatin. 2016;9:8 pubmed 出版商

Chimge N, Little G, Baniwal S, Adisetiyo H, Xie Y, Zhang T, et al. RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer. Nat Commun. 2016;7:10751 pubmed 出版商

Keuss M, Thomas Y, Mcarthur R, Wood N, Knebel A, Kurz T. Characterization of the mammalian family of DCN-type NEDD8 E3 ligases. J Cell Sci. 2016;129:1441-54 pubmed 出版商

Ladurner R, Kreidl E, Ivanov M, Ekker H, Idarraga Amado M, Busslinger G, et al. Sororin actively maintains sister chromatid cohesion. EMBO J. 2016;35:635-53 pubmed 出版商

Dolfini D, Zambelli F, Pedrazzoli M, Mantovani R, Pavesi G. A high definition look at the NF-Y regulome reveals genome-wide associations with selected transcription factors. Nucleic Acids Res. 2016;44:4684-702 pubmed 出版商

Hwang S, Jang S, Kim M, Kim L, Kim B, Kim H, et al. YY1 inhibits differentiation and function of regulatory T cells by blocking Foxp3 expression and activity. Nat Commun. 2016;7:10789 pubmed 出版商

Li X, Wu J, Li Q, Shigemura K, Chung L, Huang W. SREBP-2 promotes stem cell-like properties and metastasis by transcriptional activation of c-Myc in prostate cancer. Oncotarget. 2016;7:12869-84 pubmed 出版商

Wang P, Zhang X, Luo P, Jiang X, Zhang P, Guo J, et al. Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling. Nat Commun. 2016;7:10592 pubmed 出版商

Liu X, Tan Y, Zhang C, Zhang Y, Zhang L, Ren P, et al. NAT10 regulates p53 activation through acetylating p53 at K120 and ubiquitinating Mdm2. EMBO Rep. 2016;17:349-66 pubmed 出版商

Franciosa G, Diluvio G, Gaudio F, Giuli M, Palermo R, Grazioli P, et al. Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression. Oncogene. 2016;35:4741-51 pubmed 出版商

Czub B, Shah A, Alfano G, Kruczek P, Chakarova C, Bhattacharya S. TOPORS, a Dual E3 Ubiquitin and Sumo1 Ligase, Interacts with 26 S Protease Regulatory Subunit 4, Encoded by the PSMC1 Gene. PLoS ONE. 2016;11:e0148678 pubmed 出版商

Boeynaems S, Bogaert E, Michiels E, Gijselinck I, Sieben A, Jovičić A, et al. Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD. Sci Rep. 2016;6:20877 pubmed 出版商

Kim N, Kim M, Sung P, Bae Y, Shin E, Yoo J. Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A. Nat Commun. 2016;7:10631 pubmed 出版商

Cullen J, Abdul Murad N, Yeo A, McKenzie M, Ward M, Chong K, et al. AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation. PLoS ONE. 2016;11:e0148213 pubmed 出版商