产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
FLUKA, Sigma-Aldrich, Roche Applied Science
产品类型 :
抗体
产品名称 :
抗APOL1在兔生产的抗体
目录 :
HPA018885
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学
更多信息或购买 :
文章摘录数: 18
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:100; 图 1a
  • 免疫印迹; 人类; 1:1000; 图 5b
Chun J, Zhang J, Wilkins M, Subramanian B, Riella C, Magraner J, et al. Recruitment of APOL1 kidney disease risk variants to lipid droplets attenuates cell toxicity. Proc Natl Acad Sci U S A. 2019;116:3712-3721 pubmed 出版商
Wakashin H, Heymann J, Roshanravan H, Daneshpajouhnejad P, Rosenberg A, Shin M, et al. APOL1 renal risk variants exacerbate podocyte injury by increasing inflammatory stress. BMC Nephrol. 2020;21:371 pubmed 出版商
Davis S, Khatua A, Popik W. Nucleosomal dsDNA Stimulates APOL1 Expression in Human Cultured Podocytes by Activating the cGAS/IFI16-STING Signaling Pathway. Sci Rep. 2019;9:15485 pubmed 出版商
Shah S, Lannon H, Dias L, Zhang J, Alper S, Pollak M, et al. APOL1 Kidney Risk Variants Induce Cell Death via Mitochondrial Translocation and Opening of the Mitochondrial Permeability Transition Pore. J Am Soc Nephrol. 2019;30:2355-2368 pubmed 出版商
Ryu J, Ge M, Merscher S, Rosenberg A, Desante M, Roshanravan H, et al. APOL1 renal risk variants promote cholesterol accumulation in tissues and cultured macrophages from APOL1 transgenic mice. PLoS ONE. 2019;14:e0211559 pubmed 出版商
Okamoto K, Rausch J, Wakashin H, Fu Y, Chung J, Dummer P, et al. APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R. Commun Biol. 2018;1:188 pubmed 出版商
Cheatham A, Davis S, Khatua A, Popik W. Blocking the 5' splice site of exon 4 by a morpholino oligomer triggers APOL1 protein isoform switch. Sci Rep. 2018;8:8739 pubmed 出版商
Skorecki K, Lee J, Langefeld C, Rosset S, Tzur S, Wasser W, et al. A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy. Nephrol Dial Transplant. 2018;33:323-330 pubmed 出版商
Fontaine F, Lecordier L, Vanwalleghem G, Uzureau P, Van Reet N, Fontaine M, et al. APOLs with low pH dependence can kill all African trypanosomes. Nat Microbiol. 2017;2:1500-1506 pubmed 出版商
Madhavan S, O Toole J, Konieczkowski M, Barisoni L, Thomas D, Ganesan S, et al. APOL1 variants change C-terminal conformational dynamics and binding to SNARE protein VAMP8. JCI Insight. 2017;2: pubmed 出版商
Granado D, Muller D, Krausel V, Kruzel Davila E, Schuberth C, Eschborn M, et al. Intracellular APOL1 Risk Variants Cause Cytotoxicity Accompanied by Energy Depletion. J Am Soc Nephrol. 2017;28:3227-3238 pubmed 出版商
Hayek S, Koh K, Grams M, Wei C, Ko Y, Li J, et al. A tripartite complex of suPAR, APOL1 risk variants and ?v?3 integrin on podocytes mediates chronic kidney disease. Nat Med. 2017;23:945-953 pubmed 出版商
Beckerman P, Bi Karchin J, Park A, Qiu C, Dummer P, Soomro I, et al. Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice. Nat Med. 2017;23:429-438 pubmed 出版商
Kruzel Davila E, Shemer R, Ofir A, Bavli Kertselli I, Darlyuk Saadon I, Oren Giladi P, et al. APOL1-Mediated Cell Injury Involves Disruption of Conserved Trafficking Processes. J Am Soc Nephrol. 2017;28:1117-1130 pubmed 出版商
Heneghan J, Vandorpe D, Shmukler B, Giovinazzo J, Giovinnazo J, Raper J, et al. BH3 domain-independent apolipoprotein L1 toxicity rescued by BCL2 prosurvival proteins. Am J Physiol Cell Physiol. 2015;309:C332-47 pubmed 出版商
Cheng D, Weckerle A, Yu Y, Ma L, Zhu X, Murea M, et al. Biogenesis and cytotoxicity of APOL1 renal risk variant proteins in hepatocytes and hepatoma cells. J Lipid Res. 2015;56:1583-93 pubmed 出版商
Khatua A, Cheatham A, Kruzel E, Singhal P, Skorecki K, Popik W. Exon 4-encoded sequence is a major determinant of cytotoxicity of apolipoprotein L1. Am J Physiol Cell Physiol. 2015;309:C22-37 pubmed 出版商
Ma L, Shelness G, Snipes J, Murea M, Antinozzi P, Cheng D, et al. Localization of APOL1 protein and mRNA in the human kidney: nondiseased tissue, primary cells, and immortalized cell lines. J Am Soc Nephrol. 2015;26:339-48 pubmed 出版商
产品信息
Product No. :
HPA018885
产品名称 :
抗APOL1在兔生产的抗体
宿主 :
共轭标签 :
未共轭
抗体类型 :
多克隆
应用/描述 :
Suitable for immunoblotting: 0.04-0.4 μg/mL; immunohistochemistry: 1:2500-1:5000
物种活性 :
人类
储存 :
存放在-20°C
更多信息或购买 :
公司信息
西格玛奥德里奇
上海市徐汇区淮海中路1010号嘉华中心41楼
techservCN@sial.com
http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
公司总部: 美国
Sigma-Aldrich是一家在生命科学领域领先的且拥有高科技产品的公司,致力于为生命科学、制药化工等领域提供高质量的服务和产品。