产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
FLUKA, Sigma-Aldrich, Roche Applied Science
产品类型 :
抗体
产品名称 :
抗ZEB1在兔生产的抗体
目录 :
HPA027524
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫印迹基因敲除验证, 免疫组化基因敲除验证, 免疫细胞化学基因敲除验证
更多信息或购买 :
文章摘录数: 57
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:2000; 图 4a, 4b, 4c
Asnaghi L, White D, Key N, Choi J, Mahale A, Alkatan H, et al. ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma. Oncogene. 2019;38:2056-2075 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500
Rickelt S, Hynes R. Antibodies and methods for immunohistochemistry of extracellular matrix proteins. Matrix Biol. 2018;71-72:10-27 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Yu R, Longo J, van Leeuwen J, Mullen P, Ba Alawi W, Haibe Kains B, et al. Statin-Induced Cancer Cell Death Can Be Mechanistically Uncoupled from Prenylation of RAS Family Proteins. Cancer Res. 2018;78:1347-1357 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 6c
  • 免疫印迹; 人类; 图 1g
Siddiqui A, Vazakidou M, Schwab A, Napoli F, Fernandez Molina C, Rapa I, et al. Thymidylate synthase is functionally associated with ZEB1 and contributes to the epithelial-to-mesenchymal transition of cancer cells. J Pathol. 2017;242:221-233 pubmed 出版商
  • 免疫细胞化学基因敲除验证; 小鼠; 图 2a
  • 免疫组化基因敲除验证; 小鼠; 图 3a
  • 免疫印迹基因敲除验证; 小鼠; 1:5000; 图 2c
  • 免疫组化-石蜡切片; 小鼠; 图 3a
Brabletz S, Lasierra Losada M, Schmalhofer O, Mitschke J, Krebs A, Brabletz T, et al. Generation and characterization of mice for conditional inactivation of Zeb1. Genesis. 2017;55: pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Koch K, Hartmann R, Schröter F, Suwala A, Maciaczyk D, Krüger A, et al. Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells. Oncotarget. 2016;7:73414-73431 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:400; 图 2
Fessler E, Drost J, van Hooff S, Linnekamp J, Wang X, Jansen M, et al. TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype. EMBO Mol Med. 2016;8:745-60 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 5
Tomei P, Masola V, Granata S, Bellin G, Carratu P, Ficial M, et al. Everolimus-induced epithelial to mesenchymal transition (EMT) in bronchial/pulmonary cells: when the dosage does matter in transplantation. J Nephrol. 2016;29:881-891 pubmed
  • 免疫印迹; 人类; 1:5000; 图 2
Lehmann W, Mossmann D, Kleemann J, Mock K, Meisinger C, Brummer T, et al. ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types. Nat Commun. 2016;7:10498 pubmed 出版商
  • 免疫组化; 人类; 1:800; 图 1a
Kulemann B, Liss A, Warshaw A, Seifert S, Bronsert P, Glatz T, et al. KRAS mutations in pancreatic circulating tumor cells: a pilot study. Tumour Biol. 2016;37:7547-54 pubmed 出版商
  • 免疫组化; 人类; 图 4
  • 免疫印迹; 人类; 图 1c
Barbáchano A, Fernández Barral A, Pereira F, Segura M, Ordóñez Morán P, Carrillo de Santa Pau E, et al. SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150. Oncogene. 2016;35:2991-3003 pubmed 出版商
Tian C, Ohlund D, Rickelt S, Lidström T, Huang Y, Hao L, et al. Cancer Cell-Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma. Cancer Res. 2020;80:1461-1474 pubmed 出版商
De la Cuesta F, Passalacqua I, Rodor J, Bhushan R, Denby L, Baker A. Extracellular vesicle cross-talk between pulmonary artery smooth muscle cells and endothelium during excessive TGF-β signalling: implications for PAH vascular remodelling. Cell Commun Signal. 2019;17:143 pubmed 出版商
Yoshimoto S, Tanaka F, Morita H, Hiraki A, Hashimoto S. Hypoxia-induced HIF-1α and ZEB1 are critical for the malignant transformation of ameloblastoma via TGF-β-dependent EMT. Cancer Med. 2019;8:7822-7832 pubmed 出版商
Filipovic J, Bosic M, Cirovic S, Zivotić M, Dunđerović D, Đorđević D, et al. PRMT1 expression in renal cell tumors- application in differential diagnosis and prognostic relevance. Diagn Pathol. 2019;14:120 pubmed 出版商
Asnaghi L, White D, Yoon L, Price A, Lee G, Sahoo A, et al. Downregulation of Nodal inhibits metastatic progression in retinoblastoma. Acta Neuropathol Commun. 2019;7:137 pubmed 出版商
Yang H, Liang S, Xu D, Yang Z, Marti T, Gao Y, et al. HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer. Oncogenesis. 2019;8:45 pubmed 出版商
Matsumura Y, Ito Y, Mezawa Y, Sulidan K, Daigo Y, Hiraga T, et al. Stromal fibroblasts induce metastatic tumor cell clusters via epithelial-mesenchymal plasticity. Life Sci Alliance. 2019;2: pubmed 出版商
Kim Y, Lee S, Shim S, Kim A, Park J, Jang W, et al. Hyaluronic acid synthase 2 promotes malignant phenotypes of colorectal cancer cells through transforming growth factor beta signaling. Cancer Sci. 2019;110:2226-2236 pubmed 出版商
Hirano D, Urabe Y, Tanaka S, Nakamura K, Ninomiya Y, Yuge R, et al. Early-stage serrated adenocarcinomas are divided into several molecularly distinct subtypes. PLoS ONE. 2019;14:e0211477 pubmed 出版商
Franke F, Muller J, Abal M, Medina E, Nitsche U, Weidmann H, et al. The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer. Cell Mol Gastroenterol Hepatol. 2019;7:33-53 pubmed 出版商
Zhang Q, Wang C, Cliby W. Cancer-associated stroma significantly contributes to the mesenchymal subtype signature of serous ovarian cancer. Gynecol Oncol. 2019;152:368-374 pubmed 出版商
Rogers T, Christenson J, Greene L, O Neill K, Williams M, Gordon M, et al. Reversal of Triple-Negative Breast Cancer EMT by miR-200c Decreases Tryptophan Catabolism and a Program of Immunosuppression. Mol Cancer Res. 2019;17:30-41 pubmed 出版商
Jolly M, Preca B, Tripathi S, Jia D, George J, Hanash S, et al. Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer. APL Bioeng. 2018;2:031908 pubmed 出版商
Qiu B, Wei W, Zhu J, Fu G, Lu D. EMT induced by loss of LKB1 promotes migration and invasion of liver cancer cells through ZEB1-induced YAP signaling. Oncol Lett. 2018;16:6465-6471 pubmed 出版商
Hoang Minh L, Siebzehnrubl F, Yang C, Suzuki Hatano S, Dajac K, Loche T, et al. Infiltrative and drug-resistant slow-cycling cells support metabolic heterogeneity in glioblastoma. EMBO J. 2018;37: pubmed 出版商
Dhayat S, Traeger M, Rehkaemper J, Stroese A, Steinestel K, Wardelmann E, et al. Clinical Impact of Epithelial-to-Mesenchymal Transition Regulating MicroRNAs in Pancreatic Ductal Adenocarcinoma. Cancers (Basel). 2018;10: pubmed 出版商
Tekin C, Shi K, Daalhuisen J, Ten Brink M, Bijlsma M, Spek C. PAR1 signaling on tumor cells limits tumor growth by maintaining a mesenchymal phenotype in pancreatic cancer. Oncotarget. 2018;9:32010-32023 pubmed 出版商
Hong D, Fritz A, Finstad K, Fitzgerald M, Weinheimer A, Viens A, et al. Suppression of Breast Cancer Stem Cells and Tumor Growth by the RUNX1 Transcription Factor. Mol Cancer Res. 2018;16:1952-1964 pubmed 出版商
Cui Y, Kim H, Lee M, Yi J, Kim R, Uddin N, et al. FBXL14 abolishes breast cancer progression by targeting CDCP1 for proteasomal degradation. Oncogene. 2018;37:5794-5809 pubmed 出版商
Roumane A, Berthenet K, El Fassi C, Ichim G. Caspase-independent cell death does not elicit a proliferative response in melanoma cancer cells. BMC Cell Biol. 2018;19:11 pubmed 出版商
Rosmaninho P, Mükusch S, Piscopo V, Teixeira V, Raposo A, Warta R, et al. Zeb1 potentiates genome-wide gene transcription with Lef1 to promote glioblastoma cell invasion. EMBO J. 2018;37: pubmed 出版商
Mishra P, Tang W, Putluri V, Dorsey T, Jin F, Wang F, et al. ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming. J Clin Invest. 2018;128:323-340 pubmed 出版商
Jia D, Jolly M, Tripathi S, den Hollander P, Huang B, Lu M, et al. Distinguishing mechanisms underlying EMT tristability. Cancer Converg. 2017;1:2 pubmed 出版商
Kang H, Son H, Cui Y, Youn B, Son B, Kaushik N, et al. Phytosphingosine exhibits an anti-epithelial-mesenchymal transition function by the inhibition of EGFR signaling in human breast cancer cells. Oncotarget. 2017;8:77794-77808 pubmed 出版商
Cortés M, Sanchez Moral L, de Barrios O, Fernández Aceñero M, Martínez Campanario M, Esteve Codina A, et al. Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles. EMBO J. 2017;36:3336-3355 pubmed 出版商
Euskirchen P, Radke J, Schmidt M, Schulze Heuling E, Kadikowski E, Maricos M, et al. Cellular heterogeneity contributes to subtype-specific expression of ZEB1 in human glioblastoma. PLoS ONE. 2017;12:e0185376 pubmed 出版商
Larsson C, Ali M, Pandzic T, Lindroth A, He L, Sjöblom T. Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition. BMC Cancer. 2017;17:487 pubmed 出版商
Ball C, Oppel F, Ehrenberg K, Dubash T, Dieter S, Hoffmann C, et al. Succession of transiently active tumor-initiating cell clones in human pancreatic cancer xenografts. EMBO Mol Med. 2017;9:918-932 pubmed 出版商
Johnson M, Stone B, Thibodeau B, Baschnagel A, Galoforo S, Fortier L, et al. The significance of Trk receptors in pancreatic cancer. Tumour Biol. 2017;39:1010428317692256 pubmed 出版商
Preca B, Bajdak K, Mock K, Lehmann W, Sundararajan V, Bronsert P, et al. A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer. Oncotarget. 2017;8:11530-11543 pubmed 出版商
Galardi S, Savino M, Scagnoli F, Pellegatta S, Pisati F, Zambelli F, et al. Resetting cancer stem cell regulatory nodes upon MYC inhibition. EMBO Rep. 2016;17:1872-1889 pubmed
Montorsi L, Guizzetti F, Alecci C, Caporali A, Martello A, Atene C, et al. Loss of ZFP36 expression in colorectal cancer correlates to wnt/ ß-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of ZEB1, SOX9 and MACC1. Oncotarget. 2016;7:59144-59157 pubmed 出版商
Kim R, Kaushik N, Suh Y, Yoo K, Cui Y, Kim M, et al. Radiation driven epithelial-mesenchymal transition is mediated by Notch signaling in breast cancer. Oncotarget. 2016;7:53430-53442 pubmed 出版商
Trinh A, Trumpi K, De Sousa E Melo F, Wang X, de Jong J, Fessler E, et al. Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry. Clin Cancer Res. 2017;23:387-398 pubmed 出版商
Singh S, Howell D, Trivedi N, Kessler K, Ong T, Rosmaninho P, et al. Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition. elife. 2016;5: pubmed 出版商
Wang F, Jiang C, Sun Q, Yan F, Wang L, Fu Z, et al. Downregulation of miR‑429 and inhibition of cell migration and invasion in nasopharyngeal carcinoma. Mol Med Rep. 2016;13:3236-42 pubmed 出版商
Li X, Huang R, Li R, Trope C, Nesland J, Suo Z. Expression of zinc finger E-box-binding homeobox factor 1 in epithelial ovarian cancer: A clinicopathological analysis of 238 patients. Mol Clin Oncol. 2016;4:18-22 pubmed
Flanagan L, Meyer M, Fay J, Curry S, Bacon O, Duessmann H, et al. Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach. Cell Death Dis. 2016;7:e2087 pubmed 出版商
Kikuchi M, Yamashita K, Waraya M, Minatani N, Ushiku H, Kojo K, et al. Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer. Oncotarget. 2016;7:1741-53 pubmed 出版商
Sundararajan V, Gengenbacher N, Stemmler M, Kleemann J, Brabletz T, Brabletz S. The ZEB1/miR-200c feedback loop regulates invasion via actin interacting proteins MYLK and TKS5. Oncotarget. 2015;6:27083-96 pubmed 出版商
Asnaghi L, Gezgin G, Tripathy A, Handa J, Merbs S, van der Velden P, et al. EMT-associated factors promote invasive properties of uveal melanoma cells. Mol Vis. 2015;21:919-29 pubmed
Preca B, Bajdak K, Mock K, Sundararajan V, Pfannstiel J, Maurer J, et al. A self-enforcing CD44s/ZEB1 feedback loop maintains EMT and stemness properties in cancer cells. Int J Cancer. 2015;137:2566-77 pubmed 出版商
Mock K, Preca B, Brummer T, Brabletz S, Stemmler M, Brabletz T. The EMT-activator ZEB1 induces bone metastasis associated genes including BMP-inhibitors. Oncotarget. 2015;6:14399-412 pubmed
Meidhof S, Brabletz S, Lehmann W, Preca B, Mock K, Ruh M, et al. ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat. EMBO Mol Med. 2015;7:831-47 pubmed 出版商
Kim R, Cui Y, Yoo K, Kim I, Lee M, Choi Y, et al. Radiation promotes malignant phenotypes through SRC in breast cancer cells. Cancer Sci. 2015;106:78-85 pubmed 出版商
Davidson B, Holth A, Hellesylt E, Tan T, Huang R, Tropé C, et al. The clinical role of epithelial-mesenchymal transition and stem cell markers in advanced-stage ovarian serous carcinoma effusions. Hum Pathol. 2015;46:1-8 pubmed 出版商
产品信息
Product No. :
HPA027524
产品名称 :
抗ZEB1在兔生产的抗体
宿主 :
共轭标签 :
未共轭
抗体类型 :
多克隆
应用/描述 :
Suitable for immunofluorescence: 0.25-2 μg/mL; immunohistochemistry: 1:2500-1:5000
物种活性 :
人类
储存 :
存放在-20°C
更多信息或购买 :
公司信息
西格玛奥德里奇
上海市徐汇区淮海中路1010号嘉华中心41楼
techservCN@sial.com
http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
公司总部: 美国
Sigma-Aldrich是一家在生命科学领域领先的且拥有高科技产品的公司,致力于为生命科学、制药化工等领域提供高质量的服务和产品。