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产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
FLUKA, Sigma-Aldrich, Roche Applied Science
产品类型 :
化学品
产品名称 :
布洛芬
目录 :
I4883
文章摘录数: 423
参考文献
White R. Diffuse reflection mid-infrared spectroscopy of neat powders by using a wire mesh "Button" sample holder. Anal Chim Acta. 2020;1098:110-116 pubmed 出版商
Ghani M, Haghdoostnejad K. Woven cotton yarn-graphene oxide-layered double hydroxide composite as a sorbent for thin film microextraction of nonsteroidal anti-inflammatory drugs followed by quantitation through high performance liquid chromatography. Anal Chim Acta. 2020;1097:94-102 pubmed 出版商
Ding T, Wang S, Yang B, Li J. Biological removal of pharmaceuticals by Navicula sp. and biotransformation of bezafibrate. Chemosphere. 2020;240:124949 pubmed 出版商
Yasmeen S, Riyazuddeen -, Khatun S, Abul Qais F. Characterization of interactions between cromolyn sodium and bovine serum albumin by spectroscopic, calorimetric and computational methods. J Biomol Struct Dyn. 2020;38:722-732 pubmed 出版商
Abednejad A, Ghaee A, Morais E, Sharma M, Neves B, Freire M, et al. Polyvinylidene fluoride-Hyaluronic acid wound dressing comprised of ionic liquids for controlled drug delivery and dual therapeutic behavior. Acta Biomater. 2019;100:142-157 pubmed 出版商
Li M, Bi J, Lv B, Zheng W, Wang Z, Xiao W, et al. An experimental study of the anti-dysmenorrhea effect of Chinese herbal medicines used in Jin Gui Yao Lue. J Ethnopharmacol. 2019;245:112181 pubmed 出版商
Sengupta P, Pal U, Mondal P, Bose A. Multi-spectroscopic and computational evaluation on the binding of sinapic acid and its Cu(II) complex with bovine serum albumin. Food Chem. 2019;301:125254 pubmed 出版商
Fernández Pumarega A, Amézqueta S, Fuguet E, Rosés M. Determination of the retention factor of ionizable compounds in microemulsion electrokinetic chromatography. Anal Chim Acta. 2019;1078:221-230 pubmed 出版商
Rymut S, Lu B, Perez A, Corey D, Lamb K, Cotton C, et al. Acetyl-CoA carboxylase inhibition regulates microtubule dynamics and intracellular transport in cystic fibrosis epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2019;316:L1081-L1093 pubmed 出版商
Shokry D, Waters L, Parkes G, Mitchell J. Prediction of human intestinal absorption using micellar liquid chromatography with an aminopropyl stationary phase. Biomed Chromatogr. 2019;33:e4515 pubmed 出版商
Maurya N, Maurya J, Singh U, Dohare R, Zafaryab M, Moshahid Alam Rizvi M, et al. In Vitro Cytotoxicity and Interaction of Noscapine with Human Serum Albumin: Effect on Structure and Esterase Activity of HSA. Mol Pharm. 2019;16:952-966 pubmed 出版商
Gu Y, Yperman J, Carleer R, D Haen J, Maggen J, Vanderheyden S, et al. Adsorption and photocatalytic removal of Ibuprofen by activated carbon impregnated with TiO2 by UV-Vis monitoring. Chemosphere. 2019;217:724-731 pubmed 出版商
Liu D, Zhang H, Wei Y, Liu B, Lin Y, Li G, et al. Enhanced degradation of ibuprofen by heterogeneous electro-Fenton at circumneutral pH. Chemosphere. 2018;209:998-1006 pubmed 出版商
Prud homme S, Renault D, David J, Reynaud S. Multiscale Approach to Deciphering the Molecular Mechanisms Involved in the Direct and Intergenerational Effect of Ibuprofen on Mosquito Aedes aegypti. Environ Sci Technol. 2018;52:7937-7950 pubmed 出版商
Ren J, Zhao Y, Fry E, Stuart D. Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection. J Med Chem. 2018;61:724-733 pubmed 出版商
de Paula H, Coelho Y, Agudelo A, Rezende J, Ferreira G, Ferreira G, et al. Kinetics and thermodynamics of bovine serum albumin interactions with Congo red dye. Colloids Surf B Biointerfaces. 2017;159:737-742 pubmed 出版商
Chang C, Chen T, Chin C, Kuo Y. Enhanced electrochemical degradation of ibuprofen in aqueous solution by PtRu alloy catalyst. Chemosphere. 2017;175:76-84 pubmed 出版商
Eliaerts J, Dardenne P, Meert N, Van Durme F, Samyn N, Janssens K, et al. Rapid classification and quantification of cocaine in seized powders with ATR-FTIR and chemometrics. Drug Test Anal. 2017;9:1480-1489 pubmed 出版商
Waters L, Shokry D, Parkes G, Mitchell J. The Use of Bile Salt Micelles for the Prediction of Human Intestinal Absorption. J Pharm Sci. 2016;105:3611-3614 pubmed 出版商
Pelligand L, Suemanotham N, King J, Seewald W, Syme H, Smith K, et al. Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney. BMC Vet Res. 2015;11:296 pubmed 出版商
Harada H, Toyoda Y, Endo T, Kobayashi M. Cysteine amide adduct formation from carboxylic acid drugs via UGT-mediated bioactivation in human liver microsomes. Pharmazie. 2015;70:678-83 pubmed
Lee B, Sur B, Cho S, Yeom M, Shim I, Lee H, et al. Effect of Beta-Asarone on Impairment of Spatial Working Memory and Apoptosis in the Hippocampus of Rats Exposed to Chronic Corticosterone Administration. Biomol Ther (Seoul). 2015;23:571-81 pubmed 出版商
Chuang D, Simonyi A, Kotzbauer P, Gu Z, Sun G. Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway. J Neuroinflammation. 2015;12:199 pubmed 出版商
Massicotte V, Frara N, Harris M, Amin M, WADE C, Popoff S, et al. Prolonged performance of a high repetition low force task induces bone adaptation in young adult rats, but loss in mature rats. Exp Gerontol. 2015;72:204-17 pubmed 出版商
Azouz L, Dahmoune F, Rezgui F, G Sell C. Full factorial design optimization of anti-inflammatory drug release by PCL-PEG-PCL microspheres. Mater Sci Eng C Mater Biol Appl. 2016;58:412-9 pubmed 出版商
Chen J, Jiang Q, Wu Y, Liu P, Yao J, Lu Q, et al. Potential of Essential Oils as Penetration Enhancers for Transdermal Administration of Ibuprofen to Treat Dysmenorrhoea. Molecules. 2015;20:18219-36 pubmed 出版商
Stebbins N, Yu W, Uhrich K. Linear, Mannitol-Based Poly(anhydride-esters) with High Ibuprofen Loading and Anti-Inflammatory Activity. Biomacromolecules. 2015;16:3632-9 pubmed 出版商
Murrell D, Denham J, Harirforoosh S. Histopathology and oxidative stress analysis of concomitant misoprostol and celecoxib administration. J Toxicol Pathol. 2015;28:165-70 pubmed 出版商
Zhang C, Jayashre E, Kumar P, Nair M. Antioxidant and Antiinflammatory Compounds in Nutmeg (Myristicafragrans) Pericarp as Determined by in vitro Assays. Nat Prod Commun. 2015;10:1399-402 pubmed
Ribeiro A, Pedrosa M, Moreira N, Pereira M, Silva A. Environmental friendly method for urban wastewater monitoring of micropollutants defined in the Directive 2013/39/EU and Decision 2015/495/EU. J Chromatogr A. 2015;1418:140-9 pubmed 出版商
Kinouchi H, Matsuyama K, Kitagawa H, Kamimori H. Surface plasmon resonance assay of inhibition by pharmaceuticals for thyroxine hormone binging to transport proteins. Anal Biochem. 2016;492:43-8 pubmed 出版商
Buttiglieri G, Collado N, Casas N, Comas J, Rodriguez Roda I. Proteomics reliability for micropollutants degradation insight into activated sludge systems. Water Sci Technol. 2015;72:882-8 pubmed 出版商
Jiang Y, Hascall D, Li D, Pease J. A charged aerosol detector/chemiluminescent nitrogen detector/liquid chromatography/mass spectrometry system for regular and fragment compound analysis in drug discovery. J Chromatogr A. 2015;1411:63-8 pubmed 出版商
Ferrero Cafiero J, Gich I, Puntes M, Martínez J, Ballester M, Coimbra J, et al. Ibuprofen lysinate, quicker and less variable: relative bioavailability compared to ibuprofen base in a pediatric suspension dosage form. Int J Clin Pharmacol Ther. 2015;53:972-9 pubmed 出版商
Candish E, Wirth H, Gooley A, Shellie R, Hilder E. Characterization of large surface area polymer monoliths and their utility for rapid, selective solid phase extraction for improved sample clean up. J Chromatogr A. 2015;1410:9-18 pubmed 出版商
Li H, Thompson M, O Donnell K. Examining drug hydrophobicity in continuous wet granulation within a twin screw extruder. Int J Pharm. 2015;496:3-11 pubmed 出版商
Reiter B, Stimpfl T. Quantification of Drugs in Brain Samples. J Anal Toxicol. 2015;39:702-6 pubmed 出版商
Waite M, Tomkovich A, Quinn T, Schumann A, Dewberry L, Totsch S, et al. Efficacy of Common Analgesics for Postsurgical Pain in Rats. J Am Assoc Lab Anim Sci. 2015;54:420-5 pubmed
Qu L, Zhou Q, Denman J, Stewart P, Hapgood K, Morton D. Influence of coating material on the flowability and dissolution of dry-coated fine ibuprofen powders. Eur J Pharm Sci. 2015;78:264-72 pubmed 出版商
Ariga G, Naik P, Nandibewoor S, Chimatadar S. Study of fluorescence interaction and conformational changes of bovine serum albumin with histamine H₁ -receptor--drug epinastine hydrochloride by spectroscopic and time-resolved fluorescence methods. Biopolymers. 2015;103:646-57 pubmed 出版商
Khan N, Farooq A, Sadek B. Investigation of cyclooxygenase and signaling pathways involved in human platelet aggregation mediated by synergistic interaction of various agonists. Drug Des Devel Ther. 2015;9:3497-506 pubmed 出版商
He Y, Ho C. Amorphous Solid Dispersions: Utilization and Challenges in Drug Discovery and Development. J Pharm Sci. 2015;104:3237-58 pubmed 出版商
Casas M, Chhetri R, Ooi G, Hansen K, Litty K, Christensson M, et al. Biodegradation of pharmaceuticals in hospital wastewater by staged Moving Bed Biofilm Reactors (MBBR). Water Res. 2015;83:293-302 pubmed 出版商
Gursch J, Hohl R, Toschkoff G, Dujmovic D, Brozio J, Krumme M, et al. Continuous Processing of Active Pharmaceutical Ingredients Suspensions via Dynamic Cross-Flow Filtration. J Pharm Sci. 2015;104:3481-9 pubmed 出版商
Peng X, Wang X, Qi W, Huang R, Su R, He Z. Deciphering the binding patterns and conformation changes upon the bovine serum albumin-rosmarinic acid complex. Food Funct. 2015;6:2712-26 pubmed 出版商
Aroso I, Craveiro R, Rocha Ã, Dionísio M, Barreiros S, Reis R, et al. Design of controlled release systems for THEDES-Therapeutic deep eutectic solvents, using supercritical fluid technology. Int J Pharm. 2015;492:73-9 pubmed 出版商
Lindholm Lehto P, Ahkola H, Knuutinen J, Herve S. Occurrence of pharmaceuticals in municipal wastewater, in the recipient water, and sedimented particles of northern Lake Päijänne. Environ Sci Pollut Res Int. 2015;22:17209-23 pubmed 出版商
Zhang K, Pereira A, Martin J. Estimates of Octanol-Water Partitioning for Thousands of Dissolved Organic Species in Oil Sands Process-Affected Water. Environ Sci Technol. 2015;49:8907-13 pubmed 出版商
Hirosawa M, Sambe T, Uchida N, Lee X, Sato K, Kobayashi S. Determination of nonsteroidal anti-inflammatory drugs in human tear and plasma samples using ultra-fast liquid chromatography-tandem mass spectrometry. Jpn J Ophthalmol. 2015;59:364-71 pubmed 出版商
Aguirre Martínez G, DelValls A, Laura Martín Díaz M. Yes, caffeine, ibuprofen, carbamazepine, novobiocin and tamoxifen have an effect on Corbicula fluminea (Müller, 1774). Ecotoxicol Environ Saf. 2015;120:142-54 pubmed 出版商
Schwarting T, Pretzsch S, Debus F, Ruchholtz S, Lechler P. The Effect of Cyclooxygenase Inhibition on Tendon-Bone Healing in an In Vitro Coculture Model. Mediators Inflamm. 2015;2015:926369 pubmed 出版商
Feng Y, Zhong D, Miao H, Yang X. Carbon dots derived from rose flowers for tetracycline sensing. Talanta. 2015;140:128-133 pubmed 出版商
Djekic L, Martinovic M, Stepanovic Petrovic R, Tomic M, Micov A, Primorac M. Design of Block Copolymer Costabilized Nonionic Microemulsions and Their In Vitro and In Vivo Assessment as Carriers for Sustained Regional Delivery of Ibuprofen via Topical Administration. J Pharm Sci. 2015;104:2501-12 pubmed 出版商
Torup H, Bøgeskov M, Hansen E, Palle C, Rosenberg J, Mitchell A, et al. Transversus abdominis plane (TAP) block after robot-assisted laparoscopic hysterectomy: a randomised clinical trial. Acta Anaesthesiol Scand. 2015;59:928-35 pubmed 出版商
Meier R, Thommes M, Rasenack N, Krumme M, Moll K, Kleinebudde P. Simplified formulations with high drug loads for continuous twin-screw granulation. Int J Pharm. 2015;496:12-23 pubmed 出版商
Adedapo A, Falayi O, Oyagbemi A. Evaluation of the analgesic, anti-inflammatory, anti-oxidant, phytochemical and toxicological properties of the methanolic leaf extract of commercially processed Moringa oleifera in some laboratory animals. J Basic Clin Physiol Pharmacol. 2015;26:491-9 pubmed 出版商
Djekic L, Krajisnik D, Martinovic M, Djordjevic D, Primorac M. Characterization of gelation process and drug release profile of thermosensitive liquid lecithin/poloxamer 407 based gels as carriers for percutaneous delivery of ibuprofen. Int J Pharm. 2015;490:180-9 pubmed 出版商
Abioye A, Issah S, Kola Mustapha A. Ex vivo skin permeation and retention studies on chitosan-ibuprofen-gellan ternary nanogel prepared by in situ ionic gelation technique--a tool for controlled transdermal delivery of ibuprofen. Int J Pharm. 2015;490:112-30 pubmed 出版商
Battal D, Barnes A, Castaneto M, Martin T, Klette K, Huestis M. Urine Mescaline Screening With a Biochip Array Immunoassay and Quantification by Gas Chromatography-Mass Spectrometry. Ther Drug Monit. 2015;37:805-11 pubmed 出版商
Bryden L, Nicholson J, Doods H, Pekcec A. Deficits in spontaneous burrowing behavior in the rat bilateral monosodium iodoacetate model of osteoarthritis: an objective measure of pain-related behavior and analgesic efficacy. Osteoarthritis Cartilage. 2015;23:1605-12 pubmed 出版商
Cortell Ballester I, Figueiredo R, Valmaseda Castellón E, Gay Escoda C. Effects of Collagen Resorbable Membrane Placement After the Surgical Extraction of Impacted Lower Third Molars. J Oral Maxillofac Surg. 2015;73:1457-64 pubmed 出版商
Nakov N, Petkovska R, Ugrinova L, Kavrakovski Z, Dimitrovska A, Svinarov D. Critical development by design of a rugged HPLC-MS/MS method for direct determination of ibuprofen enantiomers in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;992:67-75 pubmed 出版商
Matongo S, Birungi G, Moodley B, Ndungu P. Pharmaceutical residues in water and sediment of Msunduzi River, KwaZulu-Natal, South Africa. Chemosphere. 2015;134:133-40 pubmed 出版商
Barfi B, Asghari A, Rajabi M, Goochani Moghadam A, Mirkhani N, Ahmadi F. Comparison of ultrasound-enhanced air-assisted liquid-liquid microextraction and low-density solvent-based dispersive liquid-liquid microextraction methods for determination of nonsteroidal anti-inflammatory drugs in human urine samples. J Pharm Biomed Anal. 2015;111:297-305 pubmed 出版商
Alsop R, Armstrong C, Maqbool A, Toppozini L, Dies H, Rheinstädter M. Cholesterol expels ibuprofen from the hydrophobic membrane core and stabilizes lamellar phases in lipid membranes containing ibuprofen. Soft Matter. 2015;11:4756-67 pubmed 出版商
Potrč T, Baumgartner S, RoÅ¡kar R, PlaninÅ¡ek O, Lavrič Z, Kristl J, et al. Electrospun polycaprolactone nanofibers as a potential oromucosal delivery system for poorly water-soluble drugs. Eur J Pharm Sci. 2015;75:101-13 pubmed 出版商
Sarveswaran S, Ghosh R, Morisetty S, Ghosh J. MK591, a second generation leukotriene biosynthesis inhibitor, prevents invasion and induces apoptosis in the bone-invading C4-2B human prostate cancer cells: implications for the treatment of castration-resistant, bone-metastatic prostate cancer. PLoS ONE. 2015;10:e0122805 pubmed 出版商
Liu W, Lirio S, Yang Y, Wu L, Hsiao S, Huang H. A poly(alkyl methacrylate-divinylbenzene-vinylbenzyl trimethylammonium chloride) monolithic column for solid-phase microextraction. J Chromatogr A. 2015;1395:32-40 pubmed 出版商
Kwong W, Liuni A, Zhou K, Parker J. Cyclooxygenase inhibition and rosuvastatin-induced vascular protection in the setting of ischemia-reperfusion: A human in vivo study. Vascul Pharmacol. 2015;71:159-65 pubmed 出版商
Beloica S, Cvijić S, Bogataj M, Parojčić J. In vitro-in vivo-in silico approach in biopharmaceutical characterization of ibuprofen IR and SR tablets. Eur J Pharm Sci. 2015;75:151-9 pubmed 出版商
Peng X, Qi W, Huang R, Su R, He Z. Elucidating the influence of gold nanoparticles on the binding of salvianolic acid B and rosmarinic acid to bovine serum albumin. PLoS ONE. 2015;10:e0118274 pubmed 出版商
Merlot A, Sahni S, Lane D, Fordham A, Pantarat N, Hibbs D, et al. Potentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cells. Oncotarget. 2015;6:10374-98 pubmed
Chen Y, Tuo J, Huang H, Liu D, You X, Mai J, et al. Optimized mixed oils remarkably reduce the amount of surfactants in microemulsions without affecting oral bioavailability of ibuprofen by simultaneously enlarging microemulsion areas and enhancing drug solubility. Int J Pharm. 2015;487:17-24 pubmed 出版商
Lyu D, Yang C, Yan X. Fabrication of aluminum terephthalate metal-organic framework incorporated polymer monolith for the microextraction of non-steroidal anti-inflammatory drugs in water and urine samples. J Chromatogr A. 2015;1393:1-7 pubmed 出版商
Hattrem M, Kristiansen K, Aachmann F, Dille M, Draget K. Ibuprofen-in-cyclodextrin-in-W/O/W emulsion - Improving the initial and long-term encapsulation efficiency of a model active ingredient. Int J Pharm. 2015;487:1-7 pubmed 出版商
Yekpe K, Abatzoglou N, Bataille B, Gosselin R, Sharkawi T, Simard J, et al. Predicting the dissolution behavior of pharmaceutical tablets with NIR chemical imaging. Int J Pharm. 2015;486:242-51 pubmed 出版商
Hsu M, Luo R, Kwek K, Por Y, Zhang Y, Chen C. Sustained release of hydrophobic drugs by the microfluidic assembly of multistage microgel/poly (lactic-co-glycolic acid) nanoparticle composites. Biomicrofluidics. 2015;9:052601 pubmed 出版商
Li X, Yang Z. Interaction of oridonin with human serum albumin by isothermal titration calorimetry and spectroscopic techniques. Chem Biol Interact. 2015;232:77-84 pubmed 出版商
Paris J, Román J, Manzano M, Cabañas M, Vallet Regí M. Tuning dual-drug release from composite scaffolds for bone regeneration. Int J Pharm. 2015;486:30-7 pubmed 出版商
Li Y, Yang J, Huang C, Wang L, Wang J, Chen J. Dendrimer-functionalized mesoporous silica as a reversed-phase/anion-exchange mixed-mode sorbent for solid phase extraction of acid drugs in human urine. J Chromatogr A. 2015;1392:28-36 pubmed 出版商
Krishnan R, Buder B, Alexander M, Foster C, Lakey J. Juvenile porcine islets can restore euglycemia in diabetic athymic nude mice after xenotransplantation. Transplantation. 2015;99:710-6 pubmed 出版商
Becker K, Salar Behzadi S, Zimmer A. Solvent-free melting techniques for the preparation of lipid-based solid oral formulations. Pharm Res. 2015;32:1519-45 pubmed 出版商
McCrudden M, Alkilani A, Courtenay A, McCrudden C, McCloskey B, Walker C, et al. Considerations in the sterile manufacture of polymeric microneedle arrays. Drug Deliv Transl Res. 2015;5:3-14 pubmed 出版商
Zailer J, Touitou E. Pouch drug delivery systems for dermal and transdermal administration. Drug Deliv Transl Res. 2014;4:416-28 pubmed 出版商
Tan A, Eskandar N, Rao S, Prestidge C. First in man bioavailability and tolerability studies of a silica-lipid hybrid (Lipoceramic) formulation: a Phase I study with ibuprofen. Drug Deliv Transl Res. 2014;4:212-21 pubmed 出版商
Atkinson H, Currie J, Moodie J, Carson S, Evans S, Worthington J, et al. Combination paracetamol and ibuprofen for pain relief after oral surgery: a dose ranging study. Eur J Clin Pharmacol. 2015;71:579-87 pubmed 出版商
Núñez M, Borrull F, Fontanals N, Pocurull E. Determination of pharmaceuticals in bivalves using QuEChERS extraction and liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2015;407:3841-9 pubmed 出版商
Zub K, Sousa M, Sarno A, Sharma A, Demirovic A, Rao S, et al. Modulation of cell metabolic pathways and oxidative stress signaling contribute to acquired melphalan resistance in multiple myeloma cells. PLoS ONE. 2015;10:e0119857 pubmed 出版商
Tian X, Huo X, Dong P, Wu B, Wang X, Wang C, et al. Sulfation of melatonin: enzymatic characterization, differences of organs, species and genders, and bioactivity variation. Biochem Pharmacol. 2015;94:282-96 pubmed 出版商
Nebot C, Falcon R, Boyd K, Gibb S. Introduction of human pharmaceuticals from wastewater treatment plants into the aquatic environment: a rural perspective. Environ Sci Pollut Res Int. 2015;22:10559-68 pubmed 出版商
Maniruzzaman M, Pang J, Morgan D, Douroumis D. Molecular modeling as a predictive tool for the development of solid dispersions. Mol Pharm. 2015;12:1040-9 pubmed 出版商
Jeffries K, Brander S, Britton M, Fangue N, Connon R. Chronic exposures to low and high concentrations of ibuprofen elicit different gene response patterns in a euryhaline fish. Environ Sci Pollut Res Int. 2015;22:17397-413 pubmed 出版商
Hu L, Hu Q, Yang J. Enhancement of transdermal delivery of ibuprofen using microemulsion vehicle. Iran J Basic Med Sci. 2014;17:760-6 pubmed
Loozen L, van der Helm Y, Oner F, Dhert W, Kruyt M, Alblas J. Bone morphogenetic protein-2 nonviral gene therapy in a goat iliac crest model for bone formation. Tissue Eng Part A. 2015;21:1672-9 pubmed 出版商
Roloff F, Scheiblich H, Dewitz C, Dempewolf S, Stern M, Bicker G. Enhanced neurite outgrowth of human model (NT2) neurons by small-molecule inhibitors of Rho/ROCK signaling. PLoS ONE. 2015;10:e0118536 pubmed 出版商
Xu Q, Wang C, Liu Q, Meng Q, Sun H, Peng J, et al. Decreased liver distribution of entecavir is related to down-regulation of Oat2/Oct1 and up-regulation of Mrp1/2/3/5 in rat liver fibrosis. Eur J Pharm Sci. 2015;71:73-9 pubmed 出版商
Obad J, Å uÅ¡ković J, Kos B. Antimicrobial activity of ibuprofen: new perspectives on an "Old" non-antibiotic drug. Eur J Pharm Sci. 2015;71:93-8 pubmed 出版商
Matongo S, Birungi G, Moodley B, Ndungu P. Occurrence of selected pharmaceuticals in water and sediment of Umgeni River, KwaZulu-Natal, South Africa. Environ Sci Pollut Res Int. 2015;22:10298-308 pubmed 出版商
Azzouz A, Ballesteros E. Multiresidue method for the determination of pharmacologically active substances in egg and honey using a continuous solid-phase extraction system and gas chromatography-mass spectrometry. Food Chem. 2015;178:63-9 pubmed 出版商
Goel R, Nagpal S, Kumar S, Kamal S, Dangda S, Bodh S. Our experience with transcanalicular laser-assisted endoscopic dacryocystorhinostomy (TCLADCR) in patients of chronic dacryocystitis with deviated nasal septum. Int Ophthalmol. 2015;35:811-7 pubmed 出版商
Zhang P, Cheng J, Zou S, D Souza A, Koff J, Lu J, et al. Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation. Nat Commun. 2015;6:6221 pubmed 出版商
Vladiskovic C, Masciocchi N. Reversibly changing a painkiller structure: a hot topic for a cold case--ibuprofen lysine salt. J Pharm Biomed Anal. 2015;107:394-402 pubmed 出版商
Merivirta R, Pitkanen M, Alanen J, Haapoja E, Koivisto M, Kuusniemi K. Postoperative pain management with transdermal fentanyl after forefoot surgery: a randomized, placebo-controlled study. J Pain Res. 2015;8:39-45 pubmed 出版商
Dong Y, Dong P, Huang D, Mei L, Xia Y, Wang Z, et al. Fabrication and characterization of silk fibroin-coated liposomes for ocular drug delivery. Eur J Pharm Biopharm. 2015;91:82-90 pubmed 出版商
Magiera S, Baranowska I. A rapid method for determination of 22 selected drugs in human urine by UHPLC/MS/MS for clinical application. J AOAC Int. 2014;97:1526-37 pubmed
Lestari M, Müller R, Möschwitzer J. Systematic screening of different surface modifiers for the production of physically stable nanosuspensions. J Pharm Sci. 2015;104:1128-40 pubmed 出版商
Oversø Hansen P, Kringelholt S, Simonsen U, Bek T. Hypoxia-induced relaxation of porcine retinal arterioles in vitro depends on inducible NO synthase and EP4 receptor stimulation in the perivascular retina. Acta Ophthalmol. 2015;93:457-63 pubmed 出版商
Rocchi S, Rocco A, Pesek J, Matyska M, Capitani D, Fanali S. Enantiomers separation by nano-liquid chromatography: use of a novel sub-2 μm vancomycin silica hydride stationary phase. J Chromatogr A. 2015;1381:149-59 pubmed 出版商
Serrano M, Gonzalez Rey M, Mattos J, Flores Nunes F, Mello Ã, Zacchi F, et al. Differential gene transcription, biochemical responses, and cytotoxicity assessment in Pacific oyster Crassostrea gigas exposed to ibuprofen. Environ Sci Pollut Res Int. 2015;22:17375-85 pubmed 出版商
Dodgen L, Ueda A, Wu X, Parker D, Gan J. Effect of transpiration on plant accumulation and translocation of PPCP/EDCs. Environ Pollut. 2015;198:144-53 pubmed 出版商
Capece M, Barrows J, Dave R. Controlled release from drug microparticles via solventless dry-polymer coating. J Pharm Sci. 2015;104:1340-51 pubmed 出版商
Curtright A, Rosser M, Goh S, Keown B, Wagner E, Sharifi J, et al. Modeling nociception in zebrafish: a way forward for unbiased analgesic discovery. PLoS ONE. 2015;10:e0116766 pubmed 出版商
Lee J, Oh S, Hwang J, Suh N, Jo D, Kim J, et al. Indomethacin preconditioning induces ischemic tolerance by modifying zinc availability in the brain. Neurobiol Dis. 2015;81:186-95 pubmed 出版商
Bannuru R, Schmid C, Kent D, Vaysbrot E, Wong J, McAlindon T. Comparative effectiveness of pharmacologic interventions for knee osteoarthritis: a systematic review and network meta-analysis. Ann Intern Med. 2015;162:46-54 pubmed 出版商
Akrami H, Aminzadeh S, Fallahi H. Inhibitory effect of ibuprofen on tumor survival and angiogenesis in gastric cancer cell. Tumour Biol. 2015;36:3237-43 pubmed 出版商
Darwish M, Yang R, Tracewell W, Robertson P, Bond M. Single- and multiple-dose pharmacokinetics of a hydrocodone bitartrate extended-release tablet formulated with abuse-deterrence technology in healthy, naltrexone-blocked volunteers. Clin Ther. 2015;37:390-401 pubmed 出版商
Vysloužil J, Dolezel P, Kejdušová M, Mašková E, Masek J, Lukáč R, et al. Influence of different formulations and process parameters during the preparation of drug-loaded PLGA microspheres evaluated by multivariate data analysis. Acta Pharm. 2014;64:403-17 pubmed 出版商
Abioye A, Kola Mustapha A. Controlled Electrostatic Self-Assembly of Ibuprofen-Cationic Dextran Nanoconjugates Prepared by low Energy Green Process - a Novel Delivery Tool for Poorly Soluble Drugs. Pharm Res. 2015;32:2110-31 pubmed 出版商
Roussel L, Gilbert E, Salmon D, Serre C, Gabard B, Haftek M, et al. Measurement, analysis and prediction of topical UV filter bioavailability. Int J Pharm. 2015;478:804-10 pubmed 出版商
Schrank S, Kann B, Saurugger E, Hainschitz M, Windbergs M, Glasser B, et al. The effect of the drying temperature on the properties of wet-extruded calcium stearate pellets: pellet microstructure, drug distribution, solid state and drug dissolution. Int J Pharm. 2015;478:779-87 pubmed 出版商
Nadaf S, Nnamani P, Jadhav N. Evaluation of Prosopis africana Seed Gum as an Extended Release Polymer for Tablet Formulation. AAPS PharmSciTech. 2015;16:716-29 pubmed 出版商
Hidalgo C, Ramos Payán M, Ocaña González J, Martín Valero M, Bello López M. Agar films containing silver nanoparticles as new supports for electromembrane extraction. Anal Bioanal Chem. 2015;407:1519-25 pubmed 出版商
Posada M, Bacon J, Schneck K, Tirona R, Kim R, Higgins J, et al. Prediction of renal transporter mediated drug-drug interactions for pemetrexed using physiologically based pharmacokinetic modeling. Drug Metab Dispos. 2015;43:325-34 pubmed 出版商
Derry C, Derry S, Moore R. Caffeine as an analgesic adjuvant for acute pain in adults. Cochrane Database Syst Rev. 2014;:CD009281 pubmed 出版商
Lolić A, Paíga P, Santos L, Ramos S, Correia M, Delerue Matos C. Assessment of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawaters of North of Portugal: occurrence and environmental risk. Sci Total Environ. 2015;508:240-50 pubmed 出版商
Mao Y, Yu L, Yang R, Qu L, Harrington P. A novel method for the study of molecular interaction by using microscale thermophoresis. Talanta. 2015;132:894-901 pubmed 出版商
González Naranjo V, Boltes K, de Bustamante I, Palacios Diaz P. Environmental risk of combined emerging pollutants in terrestrial environments: chlorophyll a fluorescence analysis. Environ Sci Pollut Res Int. 2015;22:6920-31 pubmed 出版商
Creusot N, Brion F, Piccini B, Budzinski H, Porcher J, Aït Aïssa S. BFCOD activity in fish cell lines and zebrafish embryos and its modulation by chemical ligands of human aryl hydrocarbon and nuclear receptors. Environ Sci Pollut Res Int. 2015;22:16393-404 pubmed 出版商
Rafiei A, Sleno L. Comparison of peak-picking workflows for untargeted liquid chromatography/high-resolution mass spectrometry metabolomics data analysis. Rapid Commun Mass Spectrom. 2015;29:119-27 pubmed 出版商
Bansal Y, Kaur M, Silakari O. Benzimidazole--ibuprofen/mesalamine conjugates: potential candidates for multifactorial diseases. Eur J Med Chem. 2015;89:671-82 pubmed 出版商
Watanabe A, Watari R, Ogawa K, Shimizu R, Tanaka Y, Takai N, et al. Using improved serial blood sampling method of mice to study pharmacokinetics and drug-drug interaction. J Pharm Sci. 2015;104:955-61 pubmed 出版商
Manzo V, Miró M, Richter P. Programmable flow-based dynamic sorptive microextraction exploiting an octadecyl chemically modified rotating disk extraction system for the determination of acidic drugs in urine. J Chromatogr A. 2014;1368:64-9 pubmed 出版商
Tanwar S, Di Carro M, Magi E. Innovative sampling and extraction methods for the determination of nonsteroidal anti-inflammatory drugs in water. J Pharm Biomed Anal. 2015;106:100-6 pubmed 出版商
Hou J, Wang Z, Yue Y, Li Q, Shao S. Spectroscopic analysis on structure-affinity relationship in the interactions of different oleanane-type triterpenoids with bovine serum albumin. Luminescence. 2015;30:780-9 pubmed 出版商
Manivel P, Anandakumar S, Ilanchelian M. Exploring the interaction of the photodynamic therapeutic agent thionine with bovine serum albumin: multispectroscopic and molecular docking studies. Luminescence. 2015;30:729-39 pubmed 出版商
Hutchison M, White P. Prostacyclin regulates bone growth via the Epac/Rap1 pathway. Endocrinology. 2015;156:499-510 pubmed 出版商
Jungner M, Legrell P, Lundgren S. Follow-up study of implants with turned or oxidized surfaces placed after sinus augmentation. Int J Oral Maxillofac Implants. 2014;29:1380-7 pubmed 出版商
Yang M, Feng Y, Pei H, Deng S, Wang M, Xiao X, et al. Effectiveness of Chinese massage therapy (Tui Na) for chronic low back pain: study protocol for a randomized controlled trial. Trials. 2014;15:418 pubmed 出版商
Poonai N, Bhullar G, Lin K, Papini A, Mainprize D, Howard J, et al. Oral administration of morphine versus ibuprofen to manage postfracture pain in children: a randomized trial. CMAJ. 2014;186:1358-63 pubmed 出版商
Cespi M, Perinelli D, Casettari L, Bonacucina G, Caporicci G, Rendina F, et al. Use of in-die powder densification parameters in the implementation of process analytical technologies for tablet production on industrial scale. Int J Pharm. 2014;477:140-7 pubmed 出版商
Ramos Payán M, Fernández Torres R, Pérez Bernal J, Callejón Mochón M, Bello López M. A novel approach for electromembrane extraction based on the use of silver nanometallic-decorated hollow fibers. Anal Chim Acta. 2014;849:7-11 pubmed 出版商
Berthod L, Roberts G, Whitley D, Sharpe A, Mills G. A solid-phase extraction method for rapidly determining the adsorption coefficient of pharmaceuticals in sewage sludge. Water Res. 2014;67:292-8 pubmed 出版商
Terebetski J, Michniak Kohn B. Combining ibuprofen sodium with cellulosic polymers: a deep dive into mechanisms of prolonged supersaturation. Int J Pharm. 2014;475:536-46 pubmed 出版商
Bedwell J, Pierce M, Levy M, Shah R. Ibuprofen with acetaminophen for postoperative pain control following tonsillectomy does not increase emergency department utilization. Otolaryngol Head Neck Surg. 2014;151:963-6 pubmed 出版商
Cai M, Wang R, Feng L, Zhang L. Determination of selected pharmaceuticals in tap water and drinking water treatment plant by high-performance liquid chromatography-triple quadrupole mass spectrometer in Beijing, China. Environ Sci Pollut Res Int. 2015;22:1854-67 pubmed 出版商
Wodarski R, Schuh Hofer S, Yurek D, Wafford K, Gilmour G, Treede R, et al. Development and pharmacological characterization of a model of sleep disruption-induced hypersensitivity in the rat. Eur J Pain. 2015;19:554-66 pubmed 出版商
Wang Y, Zhang H, Cao J. Exploring the interactions of decabrominateddiphenyl ether and tetrabromobisphenol A with human serum albumin. Environ Toxicol Pharmacol. 2014;38:595-606 pubmed 出版商
Alabed S, Cabello J, Irving G, Qintar M, Burls A. Colchicine for pericarditis. Cochrane Database Syst Rev. 2014;:CD010652 pubmed 出版商
Yilmaz B, Sahin H, Akba V, Erdem A. Determination of flurbiprofen in human plasma by gas chromatography with mass spectrometry and its pharmacokinetics. J AOAC Int. 2014;97:1061-6 pubmed
Takeya K, Wang X, Kathol I, Loutzenhiser K, Loutzenhiser R, Walsh M. Endothelin-1, but not angiotensin II, induces afferent arteriolar myosin diphosphorylation as a potential contributor to prolonged vasoconstriction. Kidney Int. 2015;87:370-81 pubmed 出版商
Nagane K, Kimura S, Ukai K, Ogawa N, Yamamoto H. Practical approach to prepare solid dispersion drug product using spherical silicate. Int J Pharm. 2014;475:364-71 pubmed 出版商
Perrenoud A, Farrell W, Aurigemma C, Aurigemma N, Fekete S, Guillarme D. Evaluation of stationary phases packed with superficially porous particles for the analysis of pharmaceutical compounds using supercritical fluid chromatography. J Chromatogr A. 2014;1360:275-87 pubmed 出版商
Moro I, Matozzo V, Piovan A, Moschin E, Vecchia F. Morpho-physiological effects of ibuprofen on Scenedesmus rubescens. Environ Toxicol Pharmacol. 2014;38:379-87 pubmed 出版商
Anwar Mohamed A, Barakat K, Bhat R, Noskov S, Tyrrell D, Tuszynski J, et al. A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity. Toxicol Lett. 2014;230:382-92 pubmed 出版商
Lee C, Shin Y, Nam M, Jeong K, Lee J. A new analytical method to determine non-steroidal anti-inflammatory drugs in surface water using in situ derivatization combined with ultrasound-assisted emulsification microextraction followed by gas chromatography-mass spectrometry. Talanta. 2014;129:552-9 pubmed 出版商
De Vrieze M, Verzele D, Szucs R, Sandra P, Lynen F. Evaluation of sphingomyelin, cholester, and phosphatidylcholine-based immobilized artificial membrane liquid chromatography to predict drug penetration across the blood-brain barrier. Anal Bioanal Chem. 2014;406:6179-88 pubmed 出版商
Jeronymo Ceneviva A, de Paula A, Silva L, Todorov S, Franco B, Penna A. Probiotic properties of lactic acid bacteria isolated from water-buffalo mozzarella cheese. Probiotics Antimicrob Proteins. 2014;6:141-56 pubmed 出版商
Besenhard M, Thurnberger A, Hohl R, Faulhammer E, Rattenberger J, Khinast J. Continuous API-crystal coating via coacervation in a tubular reactor. Int J Pharm. 2014;475:198-207 pubmed 出版商
Kim H, Ryu H, Kim J, Kim Y, Lee H, Jung J, et al. Validation of cyclooxygenase-2 as a direct anti-inflammatory target of 4-O-methylhonokiol in zymosan-induced animal models. Arch Pharm Res. 2015;38:813-25 pubmed 出版商
Lin B, Lyu J, Lyu X, Yu H, Hu Z, Lam J, et al. Characterization of cefalexin degradation capabilities of two Pseudomonas strains isolated from activated sludge. J Hazard Mater. 2015;282:158-64 pubmed 出版商
Manzo V, Honda L, Navarro O, Ascar L, Richter P. Microextraction of non-steroidal anti-inflammatory drugs from waste water samples by rotating-disk sorptive extraction. Talanta. 2014;128:486-92 pubmed 出版商
Corcoll N, Acuña V, Barcelo D, Casellas M, Guasch H, Huerta B, et al. Pollution-induced community tolerance to non-steroidal anti-inflammatory drugs (NSAIDs) in fluvial biofilm communities affected by WWTP effluents. Chemosphere. 2014;112:185-93 pubmed 出版商
Mattheolabakis G, Wong C, Sun Y, Amella C, Richards R, Constantinides P, et al. Pegylation improves the pharmacokinetics and bioavailability of small-molecule drugs hydrolyzable by esterases: a study of phospho-Ibuprofen. J Pharmacol Exp Ther. 2014;351:61-6 pubmed 出版商
Hou M, Chang L, Lin C, Lin L, Tsai T. Comparative pharmacokinetics of rhein in normal and loperamide-induced constipated rats and microarray analysis of drug-metabolizing genes. J Ethnopharmacol. 2014;155:1291-9 pubmed 出版商
Paíga P, Lolić A, Hellebuyck F, Santos L, Correia M, Delerue Matos C. Development of a SPE-UHPLC-MS/MS methodology for the determination of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawater. J Pharm Biomed Anal. 2015;106:61-70 pubmed 出版商
Dawas Massalha A, Gur Reznik S, Lerman S, Sabbah I, Dosoretz C. Co-metabolic oxidation of pharmaceutical compounds by a nitrifying bacterial enrichment. Bioresour Technol. 2014;167:336-42 pubmed 出版商
Snorradóttir B, Jónsdóttir F, Sigurdsson S, Másson M. Numerical modelling of transdermal delivery from matrix systems: parametric study and experimental validation with silicone matrices. J Pharm Sci. 2014;103:2366-75 pubmed 出版商
Albals D, Hendrickx A, Clincke L, Chankvetadze B, Heyden Y, Mangelings D. A chiral separation strategy for acidic drugs in capillary electrochromatography using both chlorinated and nonchlorinated polysaccharide-based selectors. Electrophoresis. 2014;35:2807-18 pubmed 出版商
Demauro S, Wright C. Acetaminophen: a possible alternative to ibuprofen in patent ductus arteriosus closure. J Pediatr. 2014;165:209-10 pubmed 出版商
Jurk D, Wilson C, Passos J, Oakley F, Correia Melo C, Greaves L, et al. Chronic inflammation induces telomere dysfunction and accelerates ageing in mice. Nat Commun. 2014;2:4172 pubmed 出版商
Tanoue R, Nomiyama K, Nakamura H, Hayashi T, Kim J, Isobe T, et al. Simultaneous determination of polar pharmaceuticals and personal care products in biological organs and tissues. J Chromatogr A. 2014;1355:193-205 pubmed 出版商
Adam R, Bilbao Ramos P, López Molina S, Abarca B, Ballesteros R, González Rosende M, et al. Triazolopyridyl ketones as a novel class of antileishmanial agents. DNA binding and BSA interaction. Bioorg Med Chem. 2014;22:4018-27 pubmed 出版商
Zhang P, Forsgren J, Strømme M. Stabilisation of amorphous ibuprofen in Upsalite, a mesoporous magnesium carbonate, as an approach to increasing the aqueous solubility of poorly soluble drugs. Int J Pharm. 2014;472:185-91 pubmed 出版商
Che Q, Quan P, Mu M, Zhang X, Zhao H, Zhang Y, et al. Enantioselective skin permeation of ibuprofen enantiomers: mechanistic insights from ATR-FTIR and CLSM studies based on synthetic enantiomers as naphthalimide fluorescent probes. Expert Opin Drug Deliv. 2014;11:1513-23 pubmed 出版商
Wang Q, He J, Yan J, Wu D, Li H. Spectroscopy and docking simulations of the interaction between lochnericine and bovine serum albumin. Luminescence. 2015;30:240-6 pubmed 出版商
Celano R, Piccinelli A, Campone L, Rastrelli L. Ultra-preconcentration and determination of selected pharmaceutical and personal care products in different water matrices by solid-phase extraction combined with dispersive liquid-liquid microextraction prior to ultra high pressure liquid chromatogr. J Chromatogr A. 2014;1355:26-35 pubmed 出版商
Canan C, Gokhale N, Carruthers B, Lafuse W, Schlesinger L, Torrelles J, et al. Characterization of lung inflammation and its impact on macrophage function in aging. J Leukoc Biol. 2014;96:473-80 pubmed 出版商
Hu Q, Yu J, Liu M, Liu A, Dou Z, Yang Y. A low cytotoxic cationic metal-organic framework carrier for controllable drug release. J Med Chem. 2014;57:5679-85 pubmed 出版商
Terebetski J, Cummings J, Fauty S, Michniak Kohn B. Combined use of crystalline sodium salt and polymeric precipitation inhibitors to improve pharmacokinetic profile of ibuprofen through supersaturation. AAPS PharmSciTech. 2014;15:1334-44 pubmed 出版商
Fujiwara R, Takenaka S, Hashimoto M, Narawa T, Itoh T. Expression of human solute carrier family transporters in skin: possible contributor to drug-induced skin disorders. Sci Rep. 2014;4:5251 pubmed 出版商
Khajeh A, Modarress H. The influence of cholesterol on interactions and dynamics of ibuprofen in a lipid bilayer. Biochim Biophys Acta. 2014;1838:2431-8 pubmed 出版商
Sun P, Wang C, Liu Q, Meng Q, Zhang A, Huo X, et al. OATP and MRP2-mediated hepatic uptake and biliary excretion of eprosartan in rat and human. Pharmacol Rep. 2014;66:311-9 pubmed 出版商
Martin J, Santos J, Aparicio I, Alonso E. Pharmaceutically active compounds in sludge stabilization treatments: anaerobic and aerobic digestion, wastewater stabilization ponds and composting. Sci Total Environ. 2015;503-504:97-104 pubmed 出版商
Apschner A, Huitema L, Ponsioen B, Peterson Maduro J, Schulte Merker S. Zebrafish enpp1 mutants exhibit pathological mineralization, mimicking features of generalized arterial calcification of infancy (GACI) and pseudoxanthoma elasticum (PXE). Dis Model Mech. 2014;7:811-22 pubmed 出版商
Jurecska L, Dobosy P, Barkács K, Fenyvesi E, Zaray G. Characterization of cyclodextrin containing nanofilters for removal of pharmaceutical residues. J Pharm Biomed Anal. 2014;98:90-3 pubmed 出版商
Abioye A, Kola Mustapha A, Chi G, Ilya S. Quantification of in situ granulation-induced changes in pre-compression, solubility, dose distribution and intrinsic in vitro release characteristics of ibuprofen-cationic dextran conjugate crystanules. Int J Pharm. 2014;471:453-77 pubmed 出版商
Komaroff A. Ask the doctor. Is it okay to take both aspirin and ibuprofen therapies?. Harv Health Lett. 2014;39:2 pubmed
Lee E, Shon H, Cho J. Role of wetland organic matters as photosensitizer for degradation of micropollutants and metabolites. J Hazard Mater. 2014;276:1-9 pubmed 出版商
Sung H, Chiu Y, Wang S, Chen C, Huang D. Acute toxicity of mixture of acetaminophen and ibuprofen to Green Neon Shrimp, Neocaridina denticulate. Environ Toxicol Pharmacol. 2014;38:8-13 pubmed 出版商
You X, Xing Q, Tuo J, Song W, Zeng Y, Hu H. Optimizing surfactant content to improve oral bioavailability of ibuprofen in microemulsions: just enough or more than enough?. Int J Pharm. 2014;471:276-84 pubmed 出版商
Mavroudi M, Kapnissi Christodoulou C. Evaluation of amino acid ester-based ionic liquids as buffer additives in CE for the separation of 2-arylpropionic acids nonsteroidal anti-inflammatory drugs. Electrophoresis. 2014;35:2573-8 pubmed 出版商
Alencar F, Viana P, Zamperini C, Becker A. Patient education and self-care for the management of jaw pain upon awakening: a randomized controlled clinical trial comparing the effectiveness of adding pharmacologic treatment with cyclobenzaprine or tizanidine. J Oral Facial Pain Headache. 2014;28:119-27 pubmed 出版商
Kim H, Kim J, Whang W, Oh M. Neuroprotective effect of Chunghyuldan from amyloid beta oligomer induced neuroinflammation in vitro and in vivo. Can J Physiol Pharmacol. 2014;92:429-37 pubmed 出版商
Liao L, Liao C, Liu C, Yang T, Wang G. Evaluation of an electrochemical biosensor for uric acid measurement in human whole blood samples. Clin Chim Acta. 2014;436:72-7 pubmed 出版商
Tabandeh H, Mortazavi S. An investigation into the drug release from ibuprofen matrix tablets with ethylcellulose and some poly-acrylate polymers. Pak J Pharm Sci. 2014;27:495-503 pubmed
Allen S, Mott K, Ghiasi H. Inhibitors of signal peptide peptidase (SPP) affect HSV-1 infectivity in vitro and in vivo. Exp Eye Res. 2014;123:8-15 pubmed 出版商
Kutsuno Y, Itoh T, Tukey R, Fujiwara R. Glucuronidation of drugs and drug-induced toxicity in humanized UDP-glucuronosyltransferase 1 mice. Drug Metab Dispos. 2014;42:1146-52 pubmed 出版商
Harrison J, Rowe R, O Hara B, Adelson P, Lifshitz J. Acute over-the-counter pharmacological intervention does not adversely affect behavioral outcome following diffuse traumatic brain injury in the mouse. Exp Brain Res. 2014;232:2709-19 pubmed 出版商
Qu L, Zhou Q, Gengenbach T, Denman J, Stewart P, Hapgood K, et al. Investigation of the potential for direct compaction of a fine ibuprofen powder dry-coated with magnesium stearate. Drug Dev Ind Pharm. 2015;41:825-37 pubmed 出版商
Har Even R, Stepensky D, Britzi M, Soback S, Chaim A, Brandriss N, et al. Plasma and cerebrospinal fluid concentrations of ibuprofen in pediatric patients and antipyretic effect: Pharmacokinetic-pharmacodynamic modeling analysis. J Clin Pharmacol. 2014;54:1023-30 pubmed 出版商
Felton L, Popescu C, Wiley C, Esposito E, Lefevre P, Hopfinger A. Experimental and computational studies of physicochemical properties influence NSAID-cyclodextrin complexation. AAPS PharmSciTech. 2014;15:872-81 pubmed 出版商
Sano S, Iwao Y, Kimura S, Noguchi S, Itai S. Impact of active ingredients on the swelling properties of orally disintegrating tablets prepared by microwave treatment. Int J Pharm. 2014;468:234-42 pubmed 出版商
Yang G, Yen C, Wang C. Monitoring and removal of residual phthalate esters and pharmaceuticals in the drinking water of Kaohsiung City, Taiwan. J Hazard Mater. 2014;277:53-61 pubmed 出版商
Lim K, Tan S, Abdullah S, Ong L, Wong M, Allen J. Percutaneous pin removal in the outpatient clinic--do children require analgesia?: a randomized controlled trial. J Bone Joint Surg Am. 2014;96:597-602 pubmed 出版商
Lalazar G, Doviner V, Ben Chetrit E. Clinical problem-solving. Unfolding the diagnosis. N Engl J Med. 2014;370:1344-8 pubmed 出版商
Naderkhani E, Isaksson J, Ryzhakov A, Flaten G. Development of a biomimetic phospholipid vesicle-based permeation assay for the estimation of intestinal drug permeability. J Pharm Sci. 2014;103:1882-90 pubmed 出版商
Kyeremateng S, Pudlas M, Woehrle G. A fast and reliable empirical approach for estimating solubility of crystalline drugs in polymers for hot melt extrusion formulations. J Pharm Sci. 2014;103:2847-2858 pubmed 出版商
Williams I, Wallom K, Smith D, Al Eisa N, Smith C, Platt F. Improved neuroprotection using miglustat, curcumin and ibuprofen as a triple combination therapy in Niemann-Pick disease type C1 mice. Neurobiol Dis. 2014;67:9-17 pubmed 出版商
Gonzalez Rey M, Mattos J, Piazza C, Bainy A, Bebianno M. Effects of active pharmaceutical ingredients mixtures in mussel Mytilus galloprovincialis. Aquat Toxicol. 2014;153:12-26 pubmed 出版商
Brasky T, Liu J, White E, Peters U, Potter J, Walter R, et al. Non-steroidal anti-inflammatory drugs and cancer risk in women: results from the Women's Health Initiative. Int J Cancer. 2014;135:1869-83 pubmed 出版商
Wolff H, Irsan -, Dodou K. Investigations on the viscoelastic performance of pressure sensitive adhesives in drug-in-adhesive type transdermal films. Pharm Res. 2014;31:2186-202 pubmed 出版商
Bertolotto M, Contini P, Ottonello L, Pende A, Dallegri F, Montecucco F. Neutrophil migration towards C5a and CXCL8 is prevented by non-steroidal anti-inflammatory drugs via inhibition of different pathways. Br J Pharmacol. 2014;171:3376-93 pubmed 出版商
Rapoff M, Connelly M, Bickel J, Powers S, Hershey A, Allen J, et al. Headstrong intervention for pediatric migraine headache: a randomized clinical trial. J Headache Pain. 2014;15:12 pubmed 出版商
Jinno N, Tagashira M, Tsurui K, Yamada S. Contribution of cytochrome P450 and UDT-glucuronosyltransferase to the metabolism of drugs containing carboxylic acid groups: risk assessment of acylglucuronides using human hepatocytes. Xenobiotica. 2014;44:677-86 pubmed 出版商
Frink L, Weatherly C, Armstrong D. Water determination in active pharmaceutical ingredients using ionic liquid headspace gas chromatography and two different detection protocols. J Pharm Biomed Anal. 2014;94:111-7 pubmed 出版商
Giovannini M, Mandelli M, Gualdi C, Palazzo S. [Ibuprofen versus steroids: risk and benefit, efficacy and safety]. Pediatr Med Chir. 2013;35:205-11 pubmed
Fukushima E, Monoi N, Mikoshiba S, Hirayama Y, Serizawa T, Adachi K, et al. Protective effects of acetaminophen on ibuprofen-induced gastric mucosal damage in rats with associated suppression of matrix metalloproteinase. J Pharmacol Exp Ther. 2014;349:165-73 pubmed 出版商
Gaul C. [Aspirin for migraine in pregnancy. This recommendation seems questionable]. MMW Fortschr Med. 2013;155:17 pubmed
Pistolozzi M, Fortugno C, Franchini C, Corbo F, Muraglia M, Roy M, et al. Species-dependent binding of tocainide analogues to albumin: affinity chromatography and circular dichroism study. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;968:69-78 pubmed 出版商
Bailey E, Worthington H, van Wijk A, Yates J, Coulthard P, Afzal Z. Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth. Cochrane Database Syst Rev. 2013;:CD004624 pubmed 出版商
Catherine B, Rood J. The application of clinical audit to improve pain control following third molar surgery. Dent Update. 2013;40:659-60, 663-4, 667-8 pubmed
Redondo Castro E, Navarro X. Chronic ibuprofen administration reduces neuropathic pain but does not exert neuroprotection after spinal cord injury in adult rats. Exp Neurol. 2014;252:95-103 pubmed 出版商
Bansal Y, Silakari O. Synthesis and pharmacological evaluation of polyfunctional benzimidazole-NSAID chimeric molecules combining anti-inflammatory, immunomodulatory and antioxidant activities. Arch Pharm Res. 2014;37:1426-36 pubmed 出版商
Wong T, Stang A, Ganshorn H, Hartling L, Maconochie I, Thomsen A, et al. Combined and alternating paracetamol and ibuprofen therapy for febrile children. Cochrane Database Syst Rev. 2013;:CD009572 pubmed 出版商
Bédouet L, Pascale F, Bonneau M, Laurent A. In vitro evaluation of S-(+)-ibuprofen as drug candidate for intra-articular drug delivery system. Drug Dev Ind Pharm. 2015;41:85-94 pubmed 出版商
Bayouth L, Safcsak K, Cheatham M, Smith C, Birrer K, Promes J. Early intravenous ibuprofen decreases narcotic requirement and length of stay after traumatic rib fracture. Am Surg. 2013;79:1207-12 pubmed
Cilurzo F, Gennari C, Selmin F, Franzé S, Musazzi U, Minghetti P. On the characterization of medicated plasters containing NSAIDs according to novel indications of USP and EMA: adhesive property and in vitro skin permeation studies. Drug Dev Ind Pharm. 2015;41:183-9 pubmed 出版商
Little P, Moore M, Kelly J, Williamson I, Leydon G, McDermott L, et al. Ibuprofen, paracetamol, and steam for patients with respiratory tract infections in primary care: pragmatic randomised factorial trial. BMJ. 2013;347:f6041 pubmed 出版商
Derry S, Best J, Moore R. Single dose oral dexibuprofen [S(+)-ibuprofen] for acute postoperative pain in adults. Cochrane Database Syst Rev. 2013;:CD007550 pubmed 出版商
Llor C, Moragas A, Bayona C, Morros R, Pera H, Plana Ripoll O, et al. Efficacy of anti-inflammatory or antibiotic treatment in patients with non-complicated acute bronchitis and discoloured sputum: randomised placebo controlled trial. BMJ. 2013;347:f5762 pubmed 出版商
Markworth J, Vella L, Lingard B, Tull D, Rupasinghe T, Sinclair A, et al. Human inflammatory and resolving lipid mediator responses to resistance exercise and ibuprofen treatment. Am J Physiol Regul Integr Comp Physiol. 2013;305:R1281-96 pubmed 出版商
Patel A, Bell M, O CONNOR C, Inchley A, Wibawa J, Lane M. Delivery of ibuprofen to the skin. Int J Pharm. 2013;457:9-13 pubmed 出版商
Qu X, Allan A, Chui G, Hutchings T, Jiao P, Johnson L, et al. Hydrolysis of ibuprofenoyl-CoA and other 2-APA-CoA esters by human acyl-CoA thioesterases-1 and -2 and their possible role in the chiral inversion of profens. Biochem Pharmacol. 2013;86:1621-5 pubmed 出版商
Eisen D, McBryde E, Walduck A. Low-dose aspirin and ibuprofen's sterilizing effects on Mycobacterium tuberculosis suggest safe new adjuvant therapies for tuberculosis. J Infect Dis. 2013;208:1925-7 pubmed 出版商
Iyengar R, Gandhi S, Aneja A, Thorpe K, Razzouk L, Greenberg J, et al. NSAIDs are associated with lower depression scores in patients with osteoarthritis. Am J Med. 2013;126:1017.e11-8 pubmed 出版商
Imazio M, Brucato A, Cemin R, Ferrua S, Maggiolini S, Beqaraj F, et al. A randomized trial of colchicine for acute pericarditis. N Engl J Med. 2013;369:1522-8 pubmed 出版商
Pilgrim J, Dobbin M, Drummer O. Fatal misuse of codeine-ibuprofen analgesics in Victoria, Australia. Med J Aust. 2013;199:329-31 pubmed
Connizzo B, Yannascoli S, Tucker J, Caro A, Riggin C, Mauck R, et al. The detrimental effects of systemic Ibuprofen delivery on tendon healing are time-dependent. Clin Orthop Relat Res. 2014;472:2433-9 pubmed 出版商
Pliskow S. Severe gynecologic sequelae of Stevens-Johnson syndrome and toxic epidermal necrolysis caused by ibuprofen: a case report. J Reprod Med. 2013;58:354-6 pubmed
Abdelbary G, Makhlouf A. Adoption of polymeric micelles to enhance the oral bioavailability of dexibuprofen: formulation, in-vitro evaluation and in-vivo pharmacokinetic study in healthy human volunteers. Pharm Dev Technol. 2014;19:717-27 pubmed 出版商
Motoc S, Remes A, Pop A, Manea F, Schoonman J. Electrochemical detection and degradation of ibuprofen from water on multi-walled carbon nanotubes-epoxy composite electrode. J Environ Sci (China). 2013;25:838-47 pubmed
Fuessl H. [Problematic: analgesics before the marathon]. MMW Fortschr Med. 2013;155:33 pubmed
Raymond E, Weaver M, Louie K, Dean G, Porsch L, Lichtenberg E, et al. Prophylactic compared with therapeutic ibuprofen analgesia in first-trimester medical abortion: a randomized controlled trial. Obstet Gynecol. 2013;122:558-64 pubmed 出版商
Immich A, Arias M, Carreras N, Boemo R, Tornero J. Drug delivery systems using sandwich configurations of electrospun poly(lactic acid) nanofiber membranes and ibuprofen. Mater Sci Eng C Mater Biol Appl. 2013;33:4002-8 pubmed 出版商
Bondarsky E, Domingo A, Matuza N, Taylor M, Thode H, Singer A. Ibuprofen vs acetaminophen vs their combination in the relief of musculoskeletal pain in the ED: a randomized, controlled trial. Am J Emerg Med. 2013;31:1357-60 pubmed 出版商
Bayen S, Zhang H, Desai M, Ooi S, Kelly B. Occurrence and distribution of pharmaceutically active and endocrine disrupting compounds in Singapore's marine environment: influence of hydrodynamics and physical-chemical properties. Environ Pollut. 2013;182:1-8 pubmed 出版商
Deeks E. Fixed-dose ibuprofen/famotidine: a review of its use to reduce the risk of gastric and duodenal ulcers in patients requiring NSAID therapy. Clin Drug Investig. 2013;33:689-97 pubmed 出版商
Li hong W, Xin C, Hui X, Li Li Z, Jing H, Mei Juan Z, et al. A novel strategy to design sustained-release poorly water-soluble drug mesoporous silica microparticles based on supercritical fluid technique. Int J Pharm. 2013;454:135-42 pubmed 出版商
Shi Y, Wei Z, Zhao H, Liu T, Dong A, Zhang J. Electrospinning of ibuprofen-loaded composite nanofibers for improving the performances of transdermal patches. J Nanosci Nanotechnol. 2013;13:3855-63 pubmed
Thu H, Ng S. Gelatine enhances drug dispersion in alginate bilayer film via the formation of crystalline microaggregates. Int J Pharm. 2013;454:99-106 pubmed 出版商
Rehman K, Amin M, Muda S. Influence of beta-cyclodextrin and chitosan in the formulation of a colon-specific drug delivery system. Drug Res (Stuttg). 2013;63:657-62 pubmed 出版商
Sharp K, Yee K, Stiles T, Aguilar R, Steward O. A re-assessment of the effects of treatment with a non-steroidal anti-inflammatory (ibuprofen) on promoting axon regeneration via RhoA inhibition after spinal cord injury. Exp Neurol. 2013;248:321-37 pubmed 出版商
Derry S, Derry C, Moore R. Single dose oral ibuprofen plus oxycodone for acute postoperative pain in adults. Cochrane Database Syst Rev. 2013;:CD010289 pubmed 出版商
Yu T, Hamill J, Evans S, Price N, Morreau P, Upadhyay V, et al. Duration of postoperative intravenous antibiotics in childhood complicated appendicitis: a propensity score-matched comparison study. Eur J Pediatr Surg. 2014;24:341-9 pubmed 出版商
Yilmaz B, Asci A, Erdem A. HPLC method for naproxen determination in human plasma and its application to a pharmacokinetic study in Turkey. J Chromatogr Sci. 2014;52:584-9 pubmed 出版商
Derry C, Derry S, Moore R. Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain. Cochrane Database Syst Rev. 2013;:CD010210 pubmed 出版商
Lee J, Park S, Park M, Kim M, Park C, Lee S, et al. Surgical suture assembled with polymeric drug-delivery sheet for sustained, local pain relief. Acta Biomater. 2013;9:8318-27 pubmed 出版商
Sunaric S, Petkovic M, Denic M, Mitić S, Pavlovic A. Determination of ibuprofen in combined dosage forms and cream by direct UV spectrophotometry after solid-phase extraction. Acta Pol Pharm. 2013;70:403-11 pubmed
Machado S, Stawiński W, Slonina P, Pinto A, Grosso J, Nouws H, et al. Application of green zero-valent iron nanoparticles to the remediation of soils contaminated with ibuprofen. Sci Total Environ. 2013;461-462:323-9 pubmed 出版商
Kumar K, Manjunath V, Shailashree M, Girish G. Coinfection with dengue and chikungunya--a case report. J Indian Med Assoc. 2012;110:749, 752 pubmed
Bhala N, Emberson J, Merhi A, Abramson S, Arber N, Baron J, et al. Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. Lancet. 2013;382:769-79 pubmed 出版商
Gertsch J, Holck P, Basnyat B, Corbett B. In reply to "ibuprofen for prevention of acute mountain sickness-is bigger really better?". Wilderness Environ Med. 2013;24:178-9 pubmed 出版商
Morozova T, Andrushchishina T, Antipova E. [Ibuprofen: safety and efficiency of its use in wide clinical practice]. Ter Arkh. 2013;85:118-24 pubmed
Luo L, Tian Y, Guo H, Li G, Zhang Z. Pharmacokinetics and bioequivalence of two ibuprofen sustained-release formulations after single and multiple doses in healthy chinese male volunteers. Drug Res (Stuttg). 2013;63:468-72 pubmed 出版商
Sarzi Puttini P, Atzeni F, Lanata L, Bagnasco M. Efficacy of ketoprofen vs. ibuprofen and diclofenac: a systematic review of the literature and meta-analysis. Clin Exp Rheumatol. 2013;31:731-8 pubmed
Imazio M, Brucato A, Barbieri A, Ferroni F, Maestroni S, Ligabue G, et al. Good prognosis for pericarditis with and without myocardial involvement: results from a multicenter, prospective cohort study. Circulation. 2013;128:42-9 pubmed 出版商
Petersen Braun M, Wegener T. [Topical gel formulation of ibuprofen in the treatment of acute and chronic joint and soft tissue pain. Results of a non-interventional observational trial]. MMW Fortschr Med. 2013;155 Suppl 1:32-9 pubmed
Rabbie R, Derry S, Moore R. Ibuprofen with or without an antiemetic for acute migraine headaches in adults. Cochrane Database Syst Rev. 2013;:CD008039 pubmed 出版商
Ohlsson A, Walia R, Shah S. Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants. Cochrane Database Syst Rev. 2013;:CD003481 pubmed 出版商
Arochena L, Zafra M, Fariña M, del Pozo V, Fernández Nieto M. Acute generalized exanthematic pustulosis due to ibuprofen. Ann Allergy Asthma Immunol. 2013;110:386-7 pubmed 出版商
Matoulková P, Dosedel M, Růzková B, Kubena A. Information and awareness concerning ibuprofen as an ingredient in over the counter analgesics: a questionnaire-based survey of residents of retirement communities. Acta Pol Pharm. 2013;70:333-8 pubmed
Lilly L. Treatment of acute and recurrent idiopathic pericarditis. Circulation. 2013;127:1723-6 pubmed 出版商
Yang E, Song E, Choi Y. Comparison of oral Ibuprofen and intravenous indomethacin for the treatment of patent ductus arteriosus in extremely low birth weight infants. J Pediatr (Rio J). 2013;89:33-9 pubmed 出版商
Kluckow M. Oral Ibuprofen and the patent ductus arteriosus: a new approach to an old problem. J Pediatr (Rio J). 2013;89:4-5 pubmed 出版商
Janaswamy S, Gill K, Campanella O, Pinal R. Organized polysaccharide fibers as stable drug carriers. Carbohydr Polym. 2013;94:209-15 pubmed 出版商
Davey J. The advantages and limitations of the analgesics available for control of postoperative pain after a dental procedure. SAAD Dig. 2013;29:70-81 pubmed
Derry S, Karlin S, Moore R. Single dose oral ibuprofen plus codeine for acute postoperative pain in adults. Cochrane Database Syst Rev. 2013;:CD010107 pubmed 出版商
Abd El Hady D, Youssef A. Hyphenation of ionic liquid albumin glassy carbon biosensor or protein label-free sensor with differential pulse stripping voltammetry for interaction studies of human serum albumin with fenoprofen enantiomers. Anal Chim Acta. 2013;772:68-74 pubmed 出版商
Crupi V, Fontana A, Giarola M, Guella G, Majolino D, Mancini I, et al. Cyclodextrin-complexation effects on the low-frequency vibrational dynamics of ibuprofen by combined inelastic light and neutron scattering experiments. J Phys Chem B. 2013;117:3917-26 pubmed 出版商
Kuan R, Holt R, Johnson K, Kent J, Peura D, Malone D. Budget impact modeling for a single-tablet formulation of ibuprofen and famotidine for prevention of upper gastrointestinal ulcers in patients with osteoarthritis and/or rheumatoid arthritis. Clin Ther. 2013;35:321-32 pubmed 出版商
Nezvalová Henriksen K, Spigset O, Nordeng H. Effects of ibuprofen, diclofenac, naproxen, and piroxicam on the course of pregnancy and pregnancy outcome: a prospective cohort study. BJOG. 2013;120:948-59 pubmed 出版商
Hasheminasab K, Fakhari A, Shahsavani A, Ahmar H. A new method for the enhancement of electromembrane extraction efficiency using carbon nanotube reinforced hollow fiber for the determination of acidic drugs in spiked plasma, urine, breast milk and wastewater samples. J Chromatogr A. 2013;1285:1-6 pubmed 出版商
Kruse J, Lachmann B, Lauer R, Eppacher S, Noe C. Lactic acid oligomers (OLAs) as prodrug moieties. Pharmazie. 2013;68:93-9 pubmed
Rutchick A, Slepian M. Handling Ibuprofen increases pain tolerance and decreases perceived pain intensity in a cold pressor test. PLoS ONE. 2013;8:e56175 pubmed 出版商
Desai N, English J. Erythema multiforme minor after ibuprofen use for menstrual pain. J Pediatr Adolesc Gynecol. 2013;26:65-8 pubmed
Wilson J, Murray L, Hughes C, Black A, Anderson L. Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer. Br J Cancer. 2013;108:1178-81 pubmed 出版商
Platts Mills T, Richmond N, Hunold K, Bowling C. Life-threatening hyperkalemia after 2 days of ibuprofen. Am J Emerg Med. 2013;31:465.e1-2 pubmed 出版商
Paloncýová M, Berka K, Otyepka M. Molecular insight into affinities of drugs and their metabolites to lipid bilayers. J Phys Chem B. 2013;117:2403-10 pubmed 出版商
Ho C, Chang S, Fulkerson D, Smith J. Children presenting with calcified disc herniation: a self-limiting process. J Radiol Case Rep. 2012;6:11-9 pubmed 出版商
Maguire T. Ibuprofen: a model medicine for self-care of common conditions. Int J Clin Pract Suppl. 2013;:43-6 pubmed 出版商
Rainsford K. Ibuprofen: from invention to an OTC therapeutic mainstay. Int J Clin Pract Suppl. 2013;:9-20 pubmed 出版商
Lodise M, De Giorgio F, Rossi R, D Aloja E, Fucci N. Acute Ibuprofen intoxication: report on a case and review of the literature. Am J Forensic Med Pathol. 2012;33:242-6 pubmed 出版商
Walker S, Choudhury J, Law S, Iazzetta J. Stability of Ibuprofen solutions in normal saline or 5% dextrose in water. Can J Hosp Pharm. 2011;64:354-61 pubmed
Argentieri J, Morrone K, Pollack Y. Acetaminophen and Ibuprofen overdosage. Pediatr Rev. 2012;33:188-9 pubmed 出版商
Adatia A, Rainsford K, Kean W. Osteoarthritis of the knee and hip. Part II: therapy with ibuprofen and a review of clinical trials. J Pharm Pharmacol. 2012;64:626-36 pubmed 出版商
Neumann R, Schulzke S, Buhrer C. Oral ibuprofen versus intravenous ibuprofen or intravenous indomethacin for the treatment of patent ductus arteriosus in preterm infants: a systematic review and meta-analysis. Neonatology. 2012;102:9-15 pubmed 出版商
Johnston P, Gillam Krakauer M, Fuller M, Reese J. Evidence-based use of indomethacin and ibuprofen in the neonatal intensive care unit. Clin Perinatol. 2012;39:111-36 pubmed 出版商
Smith H, Voss B. Pharmacokinetics of intravenous ibuprofen: implications of time of infusion in the treatment of pain and fever. Drugs. 2012;72:327-37 pubmed 出版商
Shafi S, Alam M, Mulakayala N, Mulakayala C, Vanaja G, Kalle A, et al. Synthesis of novel 2-mercapto benzothiazole and 1,2,3-triazole based bis-heterocycles: their anti-inflammatory and anti-nociceptive activities. Eur J Med Chem. 2012;49:324-33 pubmed 出版商
Hegazy G, Ali H. Design, synthesis, biological evaluation, and comparative Cox1 and Cox2 docking of p-substituted benzylidenamino phenyl esters of ibuprofenic and mefenamic acids. Bioorg Med Chem. 2012;20:1259-70 pubmed 出版商
Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W. Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS Comput Biol. 2011;7:e1002310 pubmed 出版商
Kang H, Rim H, Park J, Choi H, Choi D, Seo J, et al. In vivo evaluation of oral anti-tumoral effect of 3,4-dihydroquinazoline derivative on solid tumor. Bioorg Med Chem Lett. 2012;22:1198-201 pubmed 出版商
Nickolls S, Mace H, Fish R, Edye M, Gurrell R, Ivarsson M, et al. A Comparison of the ?2/3/5 Selective Positive Allosteric Modulators L-838,417 and TPA023 in Preclinical Models of Inflammatory and Neuropathic Pain. Adv Pharmacol Sci. 2011;2011:608912 pubmed 出版商
Jain S, Tran S, El Gendy M, Kashfi K, Jurasz P, Velazquez Martinez C. Nitric oxide release is not required to decrease the ulcerogenic profile of nonsteroidal anti-inflammatory drugs. J Med Chem. 2012;55:688-96 pubmed 出版商
Singh G, Mmatli E. Recent progress in synthesis and bioactivity studies of indolizines. Eur J Med Chem. 2011;46:5237-57 pubmed 出版商
Abdur Rahim M, Praveen Rao P, Bhardwaj A, Kaur J, Huang Z, Knaus E. Isomeric acetoxy analogs of celecoxib and their evaluation as cyclooxygenase inhibitors. Bioorg Med Chem Lett. 2011;21:6074-80 pubmed 出版商
Hieke M, Ness J, Steri R, Greiner C, Werz O, Schubert Zsilavecz M, et al. SAR studies of acidic dual γ-secretase/PPARγ modulators. Bioorg Med Chem. 2011;19:5372-82 pubmed 出版商
Sashidhara K, Kumar M, Modukuri R, Sonkar R, Bhatia G, Khanna A, et al. Synthesis and anti-inflammatory activity of novel biscoumarin-chalcone hybrids. Bioorg Med Chem Lett. 2011;21:4480-4 pubmed 出版商
Nagarapu L, Mateti J, Gaikwad H, Bantu R, Sheeba Rani M, Prameela Subhashini N. Synthesis and anti-inflammatory activity of some novel 3-phenyl-N-[3-(4-phenylpiperazin-1yl)propyl]-1H-pyrazole-5-carboxamide derivatives. Bioorg Med Chem Lett. 2011;21:4138-40 pubmed 出版商
Abdellatif K, Huang Z, Chowdhury M, Kaufman S, Knaus E. A diazen-1-ium-1,2-diolated nitric oxide donor ester prodrug of 3-(4-hydroxymethylphenyl)-4-(4-methanesulfonylphenyl)-5H-furan-2-one: synthesis, biological evaluation and nitric oxide release studies. Bioorg Med Chem Lett. 2011;21:3951-6 pubmed 出版商
Chen M, Vijay V, Shi Q, Liu Z, Fang H, Tong W. FDA-approved drug labeling for the study of drug-induced liver injury. Drug Discov Today. 2011;16:697-703 pubmed 出版商
Mohamed M, Kamel R, Fatahala S. New condensed pyrroles of potential biological interest syntheses and structure-activity relationship studies. Eur J Med Chem. 2011;46:3022-9 pubmed 出版商
Gozalbes R, Jacewicz M, Annand R, Tsaioun K, Pineda Lucena A. QSAR-based permeability model for drug-like compounds. Bioorg Med Chem. 2011;19:2615-24 pubmed 出版商
Varshney A, Rehan M, Subbarao N, Rabbani G, Khan R. Elimination of endogenous toxin, creatinine from blood plasma depends on albumin conformation: site specific uremic toxicity & impaired drug binding. PLoS ONE. 2011;6:e17230 pubmed 出版商
Mironov G, Okhonin V, Gorelsky S, Berezovski M. Revealing equilibrium and rate constants of weak and fast noncovalent interactions. Anal Chem. 2011;83:2364-70 pubmed 出版商
Liu W, Zhou J, Bensdorf K, Zhang H, Liu H, Wang Y, et al. Investigations on cytotoxicity and anti-inflammatory potency of licofelone derivatives. Eur J Med Chem. 2011;46:907-13 pubmed 出版商
Huang Z, Velazquez C, Abdellatif K, Chowdhury M, Reisz J, DuMond J, et al. Ethanesulfohydroxamic acid ester prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs): synthesis, nitric oxide and nitroxyl release, cyclooxygenase inhibition, anti-inflammatory, and ulcerogenicity index studies. J Med Chem. 2011;54:1356-64 pubmed 出版商
Talevi A, Goodarzi M, Ortiz E, Duchowicz P, Bellera C, Pesce G, et al. Prediction of drug intestinal absorption by new linear and non-linear QSPR. Eur J Med Chem. 2011;46:218-28 pubmed 出版商
Alelyunas Y, Empfield J, McCarthy D, Spreen R, Bui K, Pelosi Kilby L, et al. Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate. Bioorg Med Chem Lett. 2010;20:7312-6 pubmed 出版商
Buttar D, Colclough N, Gerhardt S, Macfaul P, Phillips S, Plowright A, et al. A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions. Bioorg Med Chem. 2010;18:7486-96 pubmed 出版商
Ekins S, Williams A, Xu J. A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug Metab Dispos. 2010;38:2302-8 pubmed 出版商
Sun X, Hu C, Deng X, Wei C, Sun Z, Quan Z. Synthesis and anti-inflammatory activity evaluation of some novel 6-alkoxy(phenoxy)-[1,2,4]triazolo[3,4-a]phthalazine-3-amine derivatives. Eur J Med Chem. 2010;45:4807-12 pubmed 出版商
Gilani S, Khan S, Siddiqui N. Synthesis and pharmacological evaluation of condensed heterocyclic 6-substituted 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole and 1,3,4-oxadiazole derivatives of isoniazid. Bioorg Med Chem Lett. 2010;20:4762-5 pubmed 出版商
Abdellatif K, Chowdhury M, Velazquez C, Huang Z, Dong Y, Das D, et al. Celecoxib prodrugs possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: synthesis, biological evaluation and nitric oxide release studies. Bioorg Med Chem Lett. 2010;20:4544-9 pubmed 出版商
Greene N, Fisk L, Naven R, Note R, Patel M, Pelletier D. Developing structure-activity relationships for the prediction of hepatotoxicity. Chem Res Toxicol. 2010;23:1215-22 pubmed 出版商
Hieke M, Ness J, Steri R, Dittrich M, Greiner C, Werz O, et al. Design, synthesis, and biological evaluation of a novel class of gamma-secretase modulators with PPARgamma activity. J Med Chem. 2010;53:4691-700 pubmed 出版商
Mohamed M, Kamel R, Fatahala S. Synthesis and biological evaluation of some thio containing pyrrolo [2,3-d]pyrimidine derivatives for their anti-inflammatory and anti-microbial activities. Eur J Med Chem. 2010;45:2994-3004 pubmed 出版商
Avdeef A, Tam K. How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?. J Med Chem. 2010;53:3566-84 pubmed 出版商
Giri R, Thaker H, Giordano T, Williams J, Rogers D, Vasu K, et al. Design, synthesis and evaluation of novel 2-thiophen-5-yl-3H-quinazolin-4-one analogues as inhibitors of transcription factors NF-kappaB and AP-1 mediated transcriptional activation: Their possible utilization as anti-inflammatory and anti-cancer age. Bioorg Med Chem. 2010;18:2796-808 pubmed 出版商
Yu G, Praveen Rao P, Chowdhury M, Abdellatif K, Dong Y, Das D, et al. Synthesis and biological evaluation of N-difluoromethyl-1,2-dihydropyrid-2-one acetic acid regioisomers: dual inhibitors of cyclooxygenases and 5-lipoxygenase. Bioorg Med Chem Lett. 2010;20:2168-73 pubmed 出版商
Sondhi S, Rani R, Singh J, Roy P, Agrawal S, Saxena A. Solvent free synthesis, anti-inflammatory and anticancer activity evaluation of tricyclic and tetracyclic benzimidazole derivatives. Bioorg Med Chem Lett. 2010;20:2306-10 pubmed 出版商
Prado Prado F, Garcia Mera X, González Díaz H. Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorg Med Chem. 2010;18:2225-2231 pubmed 出版商
Zawidlak Wegrzyńska B, Kawalec M, Bosek I, Łuczyk Juzwa M, Adamus G, Rusin A, et al. Synthesis and antiproliferative properties of ibuprofen-oligo(3-hydroxybutyrate) conjugates. Eur J Med Chem. 2010;45:1833-42 pubmed 出版商
Onnis V, Congiu C, Björklund E, Hempel F, Söderström E, Fowler C. Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors. J Med Chem. 2010;53:2286-98 pubmed 出版商
Chowdhury M, Abdellatif K, Dong Y, Yu G, Huang Z, Rahman M, et al. Celecoxib analogs possessing a N-(4-nitrooxybutyl)piperidin-4-yl or N-(4-nitrooxybutyl)-1,2,3,6-tetrahydropyridin-4-yl nitric oxide donor moiety: synthesis, biological evaluation and nitric oxide release studies. Bioorg Med Chem Lett. 2010;20:1324-9 pubmed 出版商
Varma M, Obach R, Rotter C, Miller H, Chang G, Steyn S, et al. Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. J Med Chem. 2010;53:1098-108 pubmed 出版商
Yu G, Chowdhury M, Abdellatif K, Dong Y, Praveen Rao P, Das D, et al. Phenylacetic acid regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity. Bioorg Med Chem Lett. 2010;20:896-902 pubmed 出版商
Uehara T, Ono A, Maruyama T, Kato I, Yamada H, Ohno Y, et al. The Japanese toxicogenomics project: application of toxicogenomics. Mol Nutr Food Res. 2010;54:218-27 pubmed 出版商
Fourches D, Barnes J, Day N, Bradley P, Reed J, Tropsha A. Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chem Res Toxicol. 2010;23:171-83 pubmed 出版商
Sondhi S, Rani R, Roy P, Agrawal S, Saxena A. Conventional and microwave assisted synthesis of small molecule based biologically active heterocyclic amidine derivatives. Eur J Med Chem. 2010;45:902-8 pubmed 出版商
Sondhi S, Singh J, Rani R, Gupta P, Agrawal S, Saxena A. Synthesis, anti-inflammatory and anticancer activity evaluation of some novel acridine derivatives. Eur J Med Chem. 2010;45:555-63 pubmed 出版商
Chowdhury M, Abdellatif K, Dong Y, Das D, Yu G, Velazquez C, et al. Synthesis and biological evaluation of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammato. Bioorg Med Chem Lett. 2009;19:6855-61 pubmed 出版商
. Guide to Receptors and Channels (GRAC), 4th Edition. Br J Pharmacol. 2009;158 Suppl 1:S1-254 pubmed 出版商
Du Cuny L, Song Z, Moses S, Powis G, Mash E, Meuillet E, et al. Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorg Med Chem. 2009;17:6983-92 pubmed 出版商
Hasan S, Alam M, Husain A, Khanna S, Akhtar M, Zaman M. Synthesis of 6-aminomethyl derivatives of benzopyran-4-one with dual biological properties: anti-inflammatory-analgesic and antimicrobial. Eur J Med Chem. 2009;44:4896-903 pubmed 出版商
Montecucco F, Bertolotto M, Ottonello L, Quercioli A, Mach F, Dallegri F. Oxaprozin-induced apoptosis on CD40 ligand-treated human primary monocytes is associated with the modulation of defined intracellular pathways. J Biomed Biotechnol. 2009;2009:478785 pubmed 出版商
Sui X, Sun J, Li H, Wang Y, Liu J, Liu X, et al. Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. Eur J Med Chem. 2009;44:4455-60 pubmed 出版商
El Gazzar A, Hafez H, Abbas H. S- and C-nucleosidoquinazoline as new nucleoside analogs with potential analgesic and anti-inflammatory activity. Eur J Med Chem. 2009;44:4249-58 pubmed 出版商
Abdellatif K, Chowdhury M, Dong Y, Das D, Yu G, Velazquez C, et al. Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its aminosulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies. Bioorg Med Chem. 2009;17:5182-8 pubmed 出版商
Varma M, Feng B, Obach R, Troutman M, Chupka J, Miller H, et al. Physicochemical determinants of human renal clearance. J Med Chem. 2009;52:4844-52 pubmed 出版商
Sujith K, Rao J, Shetty P, Kalluraya B. Regioselective reaction: synthesis and pharmacological study of Mannich bases containing ibuprofen moiety. Eur J Med Chem. 2009;44:3697-702 pubmed 出版商
Jayashankar B, Lokanath Rai K, Baskaran N, Sathish H. Synthesis and pharmacological evaluation of 1,3,4-oxadiazole bearing bis(heterocycle) derivatives as anti-inflammatory and analgesic agents. Eur J Med Chem. 2009;44:3898-902 pubmed 出版商
Abdellatif K, Chowdhury M, Dong Y, Das D, Yu G, Velazquez C, et al. Dinitroglyceryl and diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of aspirin, indomethacin and ibuprofen: synthesis, biological evaluation and nitric oxide release studies. Bioorg Med Chem Lett. 2009;19:3014-8 pubmed 出版商
Abdel Azeem A, Abdel Hafez A, El Karamany G, Farag H. Chlorzoxazone esters of some non-steroidal anti-inflammatory (NSAI) carboxylic acids as mutual prodrugs: design, synthesis, pharmacological investigations and docking studies. Bioorg Med Chem. 2009;17:3665-70 pubmed 出版商
Chikhale R, Bhole R, Khedekar P, Bhusari K. Synthesis and pharmacological investigation of 3-(substituted 1-phenylethanone)-4-(substituted phenyl)-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylates. Eur J Med Chem. 2009;44:3645-53 pubmed 出版商
Chowdhury M, Abdellatif K, Dong Y, Das D, Suresh M, Knaus E. Synthesis of celecoxib analogues possessing a N-difluoromethyl-1,2-dihydropyrid-2-one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity. J Med Chem. 2009;52:1525-9 pubmed 出版商
Prins L, du Preez J, van Dyk S, Malan S. Polycyclic cage structures as carrier molecules for neuroprotective non-steroidal anti-inflammatory drugs. Eur J Med Chem. 2009;44:2577-82 pubmed 出版商
Chowdhury M, Abdellatif K, Dong Y, Rahman M, Das D, Suresh M, et al. Synthesis of 1-(methanesulfonyl- and aminosulfonylphenyl)acetylenes that possess a 2-(N-difluoromethyl-1,2-dihydropyridin-2-one) pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity. Bioorg Med Chem Lett. 2009;19:584-8 pubmed 出版商
Giri R, Thaker H, Giordano T, Williams J, Rogers D, Sudersanam V, et al. Design, synthesis and characterization of novel 2-(2,4-disubstituted-thiazole-5-yl)-3-aryl-3H-quinazoline-4-one derivatives as inhibitors of NF-kappaB and AP-1 mediated transcription activation and as potential anti-inflammatory agents. Eur J Med Chem. 2009;44:2184-9 pubmed 出版商
Alam M, Husain A, Hasan S, Suruchi -, Anwer T. Synthesis and pharmacological evaluation of 2(3H)-furanones and 2(3H)-pyrrolones, combining analgesic and anti-inflammatory properties with reduced gastrointestinal toxicity and lipid peroxidation. Eur J Med Chem. 2009;44:2636-42 pubmed 出版商
Akhter M, Husain A, Azad B, Ajmal M. Aroylpropionic acid based 2,5-disubstituted-1,3,4-oxadiazoles: synthesis and their anti-inflammatory and analgesic activities. Eur J Med Chem. 2009;44:2372-8 pubmed 出版商
Wansi J, Mesaik M, Chiozem D, Devkota K, Gaboriaud Kolar N, Lallemand M, et al. Oxidative burst inhibitory and cytotoxic indoloquinazoline and furoquinoline alkaloids from Oricia suaveolens. J Nat Prod. 2008;71:1942-5 pubmed 出版商
Abdellatif K, Chowdhury M, Dong Y, Velazquez C, Das D, Suresh M, et al. Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: synthesis, biological evaluation and nitric oxide release studies. Bioorg Med Chem. 2008;16:9694-8 pubmed 出版商
Singh P, Bhardwaj A, Kaur S, Kumar S. Design, synthesis and evaluation of tetrahydropyran based COX-1/-2 inhibitors. Eur J Med Chem. 2009;44:1278-87 pubmed 出版商
Santana L, González Díaz H, Quezada E, Uriarte E, Yáñez M, Viña D, et al. Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. J Med Chem. 2008;51:6740-51 pubmed 出版商
Ahlin G, Karlsson J, Pedersen J, Gustavsson L, Larsson R, Matsson P, et al. Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. J Med Chem. 2008;51:5932-42 pubmed 出版商
Li H, Sun J, Sui X, Liu J, Yan Z, Liu X, et al. First-principle, structure-based prediction of hepatic metabolic clearance values in human. Eur J Med Chem. 2009;44:1600-6 pubmed 出版商
Sondhi S, Singh J, Kumar A, Jamal H, Gupta P. Synthesis of amidine and amide derivatives and their evaluation for anti-inflammatory and analgesic activities. Eur J Med Chem. 2009;44:1010-5 pubmed 出版商
Hafez H, Hegab M, Ahmed Farag I, el Gazzar A. A facile regioselective synthesis of novel spiro-thioxanthene and spiro-xanthene-9',2-[1,3,4]thiadiazole derivatives as potential analgesic and anti-inflammatory agents. Bioorg Med Chem Lett. 2008;18:4538-43 pubmed 出版商
Chowdhury M, Chen H, Abdellatif K, Dong Y, Petruk K, Knaus E. Synthesis and biological evaluation of 1-(benzenesulfonamido)-2-[5-(N-hydroxypyridin-2(1H)-one)]acetylene regioisomers: a novel class of 5-lipoxygenase inhibitors. Bioorg Med Chem Lett. 2008;18:4195-8 pubmed 出版商
Chuang S, Velkov T, Horne J, Porter C, Scanlon M. Characterization of the drug binding specificity of rat liver fatty acid binding protein. J Med Chem. 2008;51:3755-64 pubmed 出版商
Brunskole M, Stefane B, Zorko K, Anderluh M, Stojan J, Lanisnik Rizner T, et al. Towards the first inhibitors of trihydroxynaphthalene reductase from Curvularia lunata: synthesis of artificial substrate, homology modelling and initial screening. Bioorg Med Chem. 2008;16:5881-9 pubmed 出版商
Pedersen J, Matsson P, Bergström C, Norinder U, Hoogstraate J, Artursson P. Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). J Med Chem. 2008;51:3275-87 pubmed 出版商
Obach R, Lombardo F, Waters N. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug Metab Dispos. 2008;36:1385-405 pubmed 出版商
Abdelouahab N, Heard C. Effect of the major glycosides of Harpagophytum procumbens (Devil's Claw) on epidermal cyclooxygenase-2 (COX-2) in vitro. J Nat Prod. 2008;71:746-9 pubmed 出版商
Romeiro N, Sant Anna C, Lima L, Fraga C, Barreiro E. NSAIDs revisited: putative molecular basis of their interactions with peroxisome proliferator-activated gamma receptor (PPARgamma). Eur J Med Chem. 2008;43:1918-25 pubmed 出版商
Chatterjee N, Kulkarni A, Ghulekar S. Synthesis, pharmacological activity and hydrolytic behavior of ethylenediamine and benzathine conjugates of ibuprofen. Eur J Med Chem. 2008;43:2819-23 pubmed
Black S, Stanley W, Filipp F, Bhairo M, Verma A, Wichmann O, et al. Probing lipid- and drug-binding domains with fluorescent dyes. Bioorg Med Chem. 2008;16:1162-73 pubmed
Amir M, Kumar H, Javed S. Condensed bridgehead nitrogen heterocyclic system: synthesis and pharmacological activities of 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives of ibuprofen and biphenyl-4-yloxy acetic acid. Eur J Med Chem. 2008;43:2056-66 pubmed
Jadhav V, Kulkarni M, Rasal V, Biradar S, Vinay M. Synthesis and anti-inflammatory evaluation of methylene bridged benzofuranyl imidazo[2,1-b][1,3,4]thiadiazoles. Eur J Med Chem. 2008;43:1721-9 pubmed
Baert B, Deconinck E, Van Gele M, Slodicka M, Stoppie P, Bodé S, et al. Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorg Med Chem. 2007;15:6943-55 pubmed
Chen J, Chen P, Liao C, Huang S, Chen I. New phenylpropenoids, bis(1-phenylethyl)phenols, bisquinolinone alkaloid, and anti-inflammatory constituents from Zanthoxylum integrifoliolum. J Nat Prod. 2007;70:1444-8 pubmed
Thorarensen A, Sarver R, Tian F, Ho A, Romero D, Marotti K. Human serum albumin binding assay based on displacement of a non selective fluorescent inhibitor. Bioorg Med Chem Lett. 2007;17:4646-9 pubmed
Chen J, Lin W, Liao C, Shieh P. Anti-inflammatory benzenoids from Antrodia camphorata. J Nat Prod. 2007;70:989-92 pubmed
Kaler G, Truong D, Khandelwal A, Nagle M, Eraly S, Swaan P, et al. Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. J Biol Chem. 2007;282:23841-53 pubmed
Harrak Y, Rosell G, Daidone G, Plescia S, Schillaci D, Pujol M. Synthesis and biological activity of new anti-inflammatory compounds containing the 1,4-benzodioxine and/or pyrrole system. Bioorg Med Chem. 2007;15:4876-90 pubmed
Velazquez C, Praveen Rao P, Citro M, Keefer L, Knaus E. O2-acetoxymethyl-protected diazeniumdiolate-based NSAIDs (NONO-NSAIDs): synthesis, nitric oxide release, and biological evaluation studies. Bioorg Med Chem. 2007;15:4767-74 pubmed
Franklin P, Pillai A, Rathod P, Yerande S, Nivsarkar M, Padh H, et al. 2-Amino-5-thiazolyl motif: a novel scaffold for designing anti-inflammatory agents of diverse structures. Eur J Med Chem. 2008;43:129-34 pubmed
Fujikawa M, Nakao K, Shimizu R, Akamatsu M. QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorg Med Chem. 2007;15:3756-67 pubmed
Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed
Sondhi S, Jain S, Dinodia M, Shukla R, Raghubir R. One pot synthesis of pyrimidine and bispyrimidine derivatives and their evaluation for anti-inflammatory and analgesic activities. Bioorg Med Chem. 2007;15:3334-44 pubmed
Molvi K, Vasu K, Yerande S, Sudarsanam V, Haque N. Syntheses of new tetrasubstituted thiophenes as novel anti-inflammatory agents. Eur J Med Chem. 2007;42:1049-58 pubmed
Byrne S, Denkin S, Zhang Y. Aspirin antagonism in isoniazid treatment of tuberculosis in mice. Antimicrob Agents Chemother. 2007;51:794-5 pubmed
Siskou I, Rekka E, Kourounakis A, Chrysselis M, Tsiakitzis K, Kourounakis P. Design and study of some novel ibuprofen derivatives with potential nootropic and neuroprotective properties. Bioorg Med Chem. 2007;15:951-61 pubmed
Metwally K, Yaseen S, Lashine E, El Fayomi H, El Sadek M. Non-carboxylic analogues of arylpropionic acids: synthesis, anti-inflammatory activity and ulcerogenic potential. Eur J Med Chem. 2007;42:152-60 pubmed
Sano H, Noguchi T, Miyajima A, Hashimoto Y, Miyachi H. Anti-angiogenic activity of basic-type, selective cyclooxygenase (COX)-1 inhibitors. Bioorg Med Chem Lett. 2006;16:3068-72 pubmed
Stock N, Munoz B, Wrigley J, Shearman M, Beher D, Peachey J, et al. The geminal dimethyl analogue of Flurbiprofen as a novel Abeta42 inhibitor and potential Alzheimer's disease modifying agent. Bioorg Med Chem Lett. 2006;16:2219-23 pubmed
Gobec S, Brozic P, Rizner T. Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents. Bioorg Med Chem Lett. 2005;15:5170-5 pubmed
Larsson J, Gottfries J, Bohlin L, Backlund A. Expanding the ChemGPS chemical space with natural products. J Nat Prod. 2005;68:985-91 pubmed
Velazquez C, Praveen Rao P, Knaus E. Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies. J Med Chem. 2005;48:4061-7 pubmed
Caron G, Ermondi G. Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). J Med Chem. 2005;48:3269-79 pubmed
Goldenberg N, Jacobson L, Manco Johnson M. Brief communication: duration of platelet dysfunction after a 7-day course of Ibuprofen. Ann Intern Med. 2005;142:506-9 pubmed
Aureli L, Cruciani G, Cesta M, Anacardio R, De Simone L, Moriconi A. Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach. J Med Chem. 2005;48:2469-79 pubmed
Kiang T, Ensom M, Chang T. UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacol Ther. 2005;106:97-132 pubmed
Selvam C, Jachak S, Thilagavathi R, Chakraborti A. Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents. Bioorg Med Chem Lett. 2005;15:1793-7 pubmed
Yao M, Zhou W, Sangha S, Albert A, Chang A, Liu T, et al. Effects of nonselective cyclooxygenase inhibition with low-dose ibuprofen on tumor growth, angiogenesis, metastasis, and survival in a mouse model of colorectal cancer. Clin Cancer Res. 2005;11:1618-28 pubmed
Van Overmeire B, Allegaert K, Casaer A, Debauche C, Decaluwe W, Jespers A, et al. Prophylactic ibuprofen in premature infants: a multicentre, randomised, double-blind, placebo-controlled trial. Lancet. 2004;364:1945-9 pubmed
Al Saidan S. Transdermal self-permeation enhancement of ibuprofen. J Control Release. 2004;100:199-209 pubmed
Perioli L, Ambrogi V, Angelici F, Ricci M, Giovagnoli S, Capuccella M, et al. Development of mucoadhesive patches for buccal administration of ibuprofen. J Control Release. 2004;99:73-82 pubmed
McCrory C, Fitzgerald D. Spinal prostaglandin formation and pain perception following thoracotomy: a role for cyclooxygenase-2. Chest. 2004;125:1321-7 pubmed
Jabor V, Lanchote V, Bonato P. Enantioselective analysis of ibuprofen in human plasma by anionic cyclodextrin-modified electrokinetic chromatography. Electrophoresis. 2002;23:3041-7 pubmed
Trappe T, White F, Lambert C, Cesar D, Hellerstein M, Evans W. Effect of ibuprofen and acetaminophen on postexercise muscle protein synthesis. Am J Physiol Endocrinol Metab. 2002;282:E551-6 pubmed
Alam I, Ferrell L, Bass N. Vanishing bile duct syndrome temporally associated with ibuprofen use. Am J Gastroenterol. 1996;91:1626-30 pubmed
Bannwarth B, Lapicque F, Pehourcq F, Gillet P, Schaeverbeke T, Laborde C, et al. Stereoselective disposition of ibuprofen enantiomers in human cerebrospinal fluid. Br J Clin Pharmacol. 1995;40:266-9 pubmed
Castillo M, Smith P. Direct determination of ibuprofen and ibuprofen acyl glucuronide in plasma by high-performance liquid chromatography using solid-phase extraction. J Chromatogr. 1993;614:109-16 pubmed
Hockertz S, Heckenberger R, Emmendörffer A, Muller M. Influence of ibuprofen on the infection with Listeria monocytogenes. Arzneimittelforschung. 1995;45:104-7 pubmed
Castillo M, Smith P. Disposition and reactivity of ibuprofen and ibufenac acyl glucuronides in vivo in the rhesus monkey and in vitro with human serum albumin. Drug Metab Dispos. 1995;23:566-72 pubmed
Whitlam J, Brown K, Crooks M, Room G. Transsynovial distribution of ibuprofen in arthritic patients. Clin Pharmacol Ther. 1981;29:487-92 pubmed
Townsend R, Benedetti T, Erickson S, Cengiz C, Gillespie W, Gschwend J, et al. Excretion of ibuprofen into breast milk. Am J Obstet Gynecol. 1984;149:184-6 pubmed
Albert K, Gernaat C. Pharmacokinetics of ibuprofen. Am J Med. 1984;77:40-6 pubmed
Day R, Williams K, Graham G, Lee E, Knihinicki R, Champion G. Stereoselective disposition of ibuprofen enantiomers in synovial fluid. Clin Pharmacol Ther. 1988;43:480-7 pubmed
Laffi G, Daskalopoulos G, Kronborg I, Hsueh W, Gentilini P, Zipser R. Effects of sulindac and ibuprofen in patients with cirrhosis and ascites. An explanation for the renal-sparing effect of sulindac. Gastroenterology. 1986;90:182-7 pubmed
Salas Herrera I, Pearson R, Turner P. Concentration of ibuprofen in cervical mucus. J Pharm Pharmacol. 1991;43:142-4 pubmed
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