产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
FLUKA, Sigma-Aldrich, Roche Applied Science
产品类型 :
化学品
产品名称 :
酮洛芬
目录 :
K1751
更多信息或购买 :
文章摘录数: 179
参考文献
Wu W, Lin F, Yang X, Wang B, Lu X, Chen Q, et al. Facile synthesis of magnetic carbon nanotubes derived from ZIF-67 and application to magnetic solid-phase extraction of profens from human serum. Talanta. 2020;207:120284 pubmed 出版商
Fernández Pumarega A, Amézqueta S, Fuguet E, Rosés M. Determination of the retention factor of ionizable compounds in microemulsion electrokinetic chromatography. Anal Chim Acta. 2019;1078:221-230 pubmed 出版商
Abujaber F, Ahmad S, Neng N, Rodriguez Martin Doimeadios R, Guzmán Bernardo F, Nogueira J. Bar adsorptive microextraction coated with multi-walled carbon nanotube phases - Application for trace analysis of pharmaceuticals in environmental waters. J Chromatogr A. 2019;1600:17-22 pubmed 出版商
Shokry D, Waters L, Parkes G, Mitchell J. Prediction of human intestinal absorption using micellar liquid chromatography with an aminopropyl stationary phase. Biomed Chromatogr. 2019;33:e4515 pubmed 出版商
Waters L, Shokry D, Parkes G, Mitchell J. The Use of Bile Salt Micelles for the Prediction of Human Intestinal Absorption. J Pharm Sci. 2016;105:3611-3614 pubmed 出版商
Chen X, Stoneburner K, Ladika M, Kuo T, Kalantar T. High-Throughput Raman Spectroscopy Screening of Excipients for the Stabilization of Amorphous Drugs. Appl Spectrosc. 2015;69:1271-80 pubmed 出版商
Harada H, Toyoda Y, Endo T, Kobayashi M. Cysteine amide adduct formation from carboxylic acid drugs via UGT-mediated bioactivation in human liver microsomes. Pharmazie. 2015;70:678-83 pubmed
Bliley J, Satish L, McLaughlin M, Kling R, Day J, Grahovac T, et al. Imaging the Stromal Vascular Fraction during Soft-Tissue Reconstruction. Plast Reconstr Surg. 2015;136:1205-15 pubmed 出版商
Becerra Herrera M, Honda L, Richter P. Ultra-high-performance liquid chromatography-Time-of-flight high resolution mass spectrometry to quantify acidic drugs in wastewater. J Chromatogr A. 2015;1423:96-103 pubmed 出版商
Yuan J, Li W, Huang J, Guo X, Li X, Lu X, et al. Transplantation of human adipose stem cell-derived hepatocyte-like cells with restricted localization to liver using acellular amniotic membrane. Stem Cell Res Ther. 2015;6:217 pubmed 出版商
Kolacz M, Karlinski M, Walerzak K, Trzebicki J. Preoperative Local Administration of Morphine as an Add-on Therapy in Patients Undergoing Surgical Removal of an Odontogenic Maxillary Cyst. A Randomized, Double-Blind Pilot Study. J Oral Facial Pain Headache. 2015;29:378-83 pubmed 出版商
Kumar V, Cabana H. Towards high potential magnetic biocatalysts for on-demand elimination of pharmaceuticals. Bioresour Technol. 2016;200:81-9 pubmed 出版商
Chen X, Vollertsen J, Nielsen J, Dall A, Bester K. Degradation of PPCPs in activated sludge from different WWTPs in Denmark. Ecotoxicology. 2015;24:2073-80 pubmed 出版商
Ribeiro N, Panizza H, Santos K, Ferreira Neto H, Antunes V. Salt-induced sympathoexcitation involves vasopressin V1a receptor activation in the paraventricular nucleus of the hypothalamus. Am J Physiol Regul Integr Comp Physiol. 2015;309:R1369-79 pubmed 出版商
Jiang Y, Hascall D, Li D, Pease J. A charged aerosol detector/chemiluminescent nitrogen detector/liquid chromatography/mass spectrometry system for regular and fragment compound analysis in drug discovery. J Chromatogr A. 2015;1411:63-8 pubmed 出版商
Waite M, Tomkovich A, Quinn T, Schumann A, Dewberry L, Totsch S, et al. Efficacy of Common Analgesics for Postsurgical Pain in Rats. J Am Assoc Lab Anim Sci. 2015;54:420-5 pubmed
Marini D, Pippia J, Colditz I, Hinch G, Petherick J, Lee C. Randomised trial of the bioavailability and efficacy of orally administered flunixin, carprofen and ketoprofen in a pain model in sheep. Aust Vet J. 2015;93:265-70 pubmed 出版商
Chantasart D, Chootanasoontorn S, Suksiriworapong J, Li S. Investigation of pH Influence on Skin Permeation Behavior of Weak Acids Using Nonsteroidal Anti-Inflammatory Drugs. J Pharm Sci. 2015;104:3459-70 pubmed 出版商
Mendoza Azpur G, Olaechea A, Pinazo M, Gomez C, Salinas E, de la Rosa M, et al. Histomorphometric Evaluation of Ridge Preservation With and Without Connective Tissue Graft Over Buccal Plate Using Different Types of Bone Substitute: An Animal Study. Implant Dent. 2015;24:686-92 pubmed 出版商
Nishi I, Kawakami T, Onodera S. Monitoring the concentrations of nonsteroidal anti-inflammatory drugs and cyclooxygenase-inhibiting activities in the surface waters of the Tone Canal and Edo River Basin. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2015;50:1108-15 pubmed 出版商
Lin Y, Huang H, Hsu W. Application of capillary electrophoresis with electrokinetic supercharging and sweeping for the on-line preconcentration of phenolic acids. Anal Bioanal Chem. 2015;407:7093-100 pubmed 出版商
Tayyab S, Zaroog M, Feroz S, Mohamad S, Malek S. Exploring the interaction between the antiallergic drug, tranilast and human serum albumin: Insights from calorimetric, spectroscopic and modeling studies. Int J Pharm. 2015;491:352-8 pubmed 出版商
Wulff R, Rappen G, Koziolek M, Garbacz G, Leopold C. Controlled release of acidic drugs in compendial and physiological hydrogen carbonate buffer from polymer blend-coated oral solid dosage forms. Eur J Pharm Sci. 2015;77:246-53 pubmed 出版商
Cerciello A, Auriemma G, Morello S, Pinto A, Del Gaudio P, Russo P, et al. Design and In Vivo Anti-Inflammatory Effect of Ketoprofen Delayed Delivery Systems. J Pharm Sci. 2015;104:3451-8 pubmed 出版商
Nishida H, Hirota M, Seto Y, Suzuki G, Kato M, Kitagaki M, et al. Non-animal photosafety screening for complex cosmetic ingredients with photochemical and photobiochemical assessment tools. Regul Toxicol Pharmacol. 2015;72:578-85 pubmed 出版商
Krieg B, Taghavi S, Amidon G, Amidon G. In Vivo Predictive Dissolution: Comparing the Effect of Bicarbonate and Phosphate Buffer on the Dissolution of Weak Acids and Weak Bases. J Pharm Sci. 2015;104:2894-904 pubmed 出版商
Manoharan P, Wong Y, Tayyab S. Stabilization of Human Serum Albumin against Urea Denaturation by Diazepam and Ketoprofen. Protein Pept Lett. 2015;22:611-7 pubmed
Nakov N, Petkovska R, Ugrinova L, Kavrakovski Z, Dimitrovska A, Svinarov D. Critical development by design of a rugged HPLC-MS/MS method for direct determination of ibuprofen enantiomers in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;992:67-75 pubmed 出版商
Bamji S, Page R, Patel D, Sanders A, Alvarez A, Gambrell C, et al. Soy glyceollins regulate transcript abundance in the female mouse brain. Funct Integr Genomics. 2015;15:549-61 pubmed 出版商
Padró J, Osorio Grisales J, Arancibia J, Olivieri A, Castells C. Scope of partial least-squares regression applied to the enantiomeric composition determination of ketoprofen from strongly overlapped chromatographic profiles. J Sep Sci. 2015;38:2423-30 pubmed 出版商
Wang Y, Wan P. Ketoprofen as a photoinitiator for anionic polymerization. Photochem Photobiol Sci. 2015;14:1120-6 pubmed 出版商
Liu W, Lirio S, Yang Y, Wu L, Hsiao S, Huang H. A poly(alkyl methacrylate-divinylbenzene-vinylbenzyl trimethylammonium chloride) monolithic column for solid-phase microextraction. J Chromatogr A. 2015;1395:32-40 pubmed 出版商
Li Y, Yang J, Huang C, Wang L, Wang J, Chen J. Dendrimer-functionalized mesoporous silica as a reversed-phase/anion-exchange mixed-mode sorbent for solid phase extraction of acid drugs in human urine. J Chromatogr A. 2015;1392:28-36 pubmed 出版商
Núñez M, Borrull F, Fontanals N, Pocurull E. Determination of pharmaceuticals in bivalves using QuEChERS extraction and liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2015;407:3841-9 pubmed 出版商
Szkudlarek A, SuÅ‚kowska A, Maciążek Jurczyk M, Chudzik M, Równicka Zubik J. Effects of non-enzymatic glycation in human serum albumin. Spectroscopic analysis. Spectrochim Acta A Mol Biomol Spectrosc. 2016;152:645-53 pubmed 出版商
Azzouz A, Ballesteros E. Multiresidue method for the determination of pharmacologically active substances in egg and honey using a continuous solid-phase extraction system and gas chromatography-mass spectrometry. Food Chem. 2015;178:63-9 pubmed 出版商
Szymusik I, GrzechociÅ„ska B, Marianowski P, KaczyÅ„ski B, WielgoÅ› M. Factors influencing the severity of pain during hysterosalpingography. Int J Gynaecol Obstet. 2015;129:118-22 pubmed 出版商
Rocchi S, Rocco A, Pesek J, Matyska M, Capitani D, Fanali S. Enantiomers separation by nano-liquid chromatography: use of a novel sub-2 μm vancomycin silica hydride stationary phase. J Chromatogr A. 2015;1381:149-59 pubmed 出版商
McConell G, Kaur G, Falcão Tebas F, Hong Y, Gatford K. Acute exercise increases insulin sensitivity in adult sheep: a new preclinical model. Am J Physiol Regul Integr Comp Physiol. 2015;308:R500-6 pubmed 出版商
Miller T, McEneff G, Brown R, Owen S, Bury N, Barron L. Pharmaceuticals in the freshwater invertebrate, Gammarus pulex, determined using pulverised liquid extraction, solid phase extraction and liquid chromatography-tandem mass spectrometry. Sci Total Environ. 2015;511:153-60 pubmed 出版商
Hidalgo C, Ramos Payán M, Ocaña González J, Martín Valero M, Bello López M. Agar films containing silver nanoparticles as new supports for electromembrane extraction. Anal Bioanal Chem. 2015;407:1519-25 pubmed 出版商
Lolić A, Paíga P, Santos L, Ramos S, Correia M, Delerue Matos C. Assessment of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawaters of North of Portugal: occurrence and environmental risk. Sci Total Environ. 2015;508:240-50 pubmed 出版商
Diniz M, Salgado R, Pereira V, Carvalho G, Oehmen A, Reis M, et al. Ecotoxicity of ketoprofen, diclofenac, atenolol and their photolysis byproducts in zebrafish (Danio rerio). Sci Total Environ. 2015;505:282-9 pubmed 出版商
Han S, Hu L, Quach T, Simpson J, Trevaskis N, Porter C. Profiling the role of deacylation-reacylation in the lymphatic transport of a triglyceride-mimetic prodrug. Pharm Res. 2015;32:1830-44 pubmed 出版商
Manzo V, Miró M, Richter P. Programmable flow-based dynamic sorptive microextraction exploiting an octadecyl chemically modified rotating disk extraction system for the determination of acidic drugs in urine. J Chromatogr A. 2014;1368:64-9 pubmed 出版商
Tanwar S, Di Carro M, Magi E. Innovative sampling and extraction methods for the determination of nonsteroidal anti-inflammatory drugs in water. J Pharm Biomed Anal. 2015;106:100-6 pubmed 出版商
Durgan D, Crossland R, Lloyd E, Phillips S, Bryan R. Increased cerebrovascular sensitivity to endothelin-1 in a rat model of obstructive sleep apnea: a role for endothelin receptor B. J Cereb Blood Flow Metab. 2015;35:402-11 pubmed 出版商
Janovszky A, Szabo A, Varga R, Garab D, Boros M, Mester C, et al. Periosteal microcirculatory reactions in a zoledronate-induced osteonecrosis model of the jaw in rats. Clin Oral Investig. 2015;19:1279-88 pubmed 出版商
Ramos Payán M, Fernández Torres R, Pérez Bernal J, Callejón Mochón M, Bello López M. A novel approach for electromembrane extraction based on the use of silver nanometallic-decorated hollow fibers. Anal Chim Acta. 2014;849:7-11 pubmed 出版商
Prezotti F, Cury B, Evangelista R. Mucoadhesive beads of gellan gum/pectin intended to controlled delivery of drugs. Carbohydr Polym. 2014;113:286-95 pubmed 出版商
Barczynski M, Konturek A, Nowak W. Randomized clinical trial of posterior retroperitoneoscopic adrenalectomy versus lateral transperitoneal laparoscopic adrenalectomy with a 5-year follow-up. Ann Surg. 2014;260:740-7; discussion 747-8 pubmed 出版商
Krieg B, Taghavi S, Amidon G, Amidon G. In vivo predictive dissolution: transport analysis of the CO2 , bicarbonate in vivo buffer system. J Pharm Sci. 2014;103:3473-3490 pubmed 出版商
Cai M, Wang R, Feng L, Zhang L. Determination of selected pharmaceuticals in tap water and drinking water treatment plant by high-performance liquid chromatography-triple quadrupole mass spectrometer in Beijing, China. Environ Sci Pollut Res Int. 2015;22:1854-67 pubmed 出版商
Fox L, Gerber M, du Preez J, du Plessis J, Hamman J. Skin permeation enhancement effects of the gel and whole-leaf materials of Aloe vera, Aloe marlothii and Aloe ferox. J Pharm Pharmacol. 2015;67:96-106 pubmed 出版商
Magiera S, Baranowska I. A new and fast strategy based on semiautomatic microextraction by packed sorbent followed by ultra high performance liquid chromatography for the analysis of drugs and their metabolites in human urine. J Sep Sci. 2014;37:3314-5 pubmed 出版商
GaweÅ‚ M, Lipkowska A, Herman M, Golasik M, Piekoszewski W, Gomolka E, et al. Chronic treatment with zinc hydroaspartate induces anti-inflammatory and anti-ulcerogenic activity in rats. Pharmacol Rep. 2014;66:862-6 pubmed 出版商
Maciążek Jurczyk M. Phenylbutazone and ketoprofen binding to serum albumin. Fluorescence study. Pharmacol Rep. 2014;66:727-31 pubmed 出版商
Perrenoud A, Farrell W, Aurigemma C, Aurigemma N, Fekete S, Guillarme D. Evaluation of stationary phases packed with superficially porous particles for the analysis of pharmaceutical compounds using supercritical fluid chromatography. J Chromatogr A. 2014;1360:275-87 pubmed 出版商
Lee C, Shin Y, Nam M, Jeong K, Lee J. A new analytical method to determine non-steroidal anti-inflammatory drugs in surface water using in situ derivatization combined with ultrasound-assisted emulsification microextraction followed by gas chromatography-mass spectrometry. Talanta. 2014;129:552-9 pubmed 出版商
Trasi N, Baird J, Kestur U, Taylor L. Factors influencing crystal growth rates from undercooled liquids of pharmaceutical compounds. J Phys Chem B. 2014;118:9974-82 pubmed 出版商
Kang J, Park S, Park H, Gedi V, So B, Lee K. Multiresidue determination of ten nonsteroidal anti-inflammatory drugs in bovine, porcine, and chicken liver tissues by HPLC-MS/MS. Appl Biochem Biotechnol. 2014;174:1-5 pubmed 出版商
Reddy I, Wasserman D, Ayala J, Hasty A, Abumrad N, Galli A. Striatal dopamine homeostasis is altered in mice following Roux-en-Y gastric bypass surgery. ACS Chem Neurosci. 2014;5:943-51 pubmed 出版商
Manzo V, Honda L, Navarro O, Ascar L, Richter P. Microextraction of non-steroidal anti-inflammatory drugs from waste water samples by rotating-disk sorptive extraction. Talanta. 2014;128:486-92 pubmed 出版商
Montesdeoca Esponda S, Mahugo Santana C, Sosa Ferrera Z, Santana Rodríguez J. A dispersive liquid-liquid micellar microextraction for the determination of pharmaceutical compounds in wastewaters using ultra-high-performace liquid chromatography with DAD detection. Biomed Chromatogr. 2015;29:353-6 pubmed 出版商
Asakawa Y, Yamamoto E, Asakawa N. Selective retention of basic compounds by metal aquo-ion affinity chromatography. J Sep Sci. 2014;37:2641-51 pubmed 出版商
Paíga P, Lolić A, Hellebuyck F, Santos L, Correia M, Delerue Matos C. Development of a SPE-UHPLC-MS/MS methodology for the determination of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawater. J Pharm Biomed Anal. 2015;106:61-70 pubmed 出版商
Dawas Massalha A, Gur Reznik S, Lerman S, Sabbah I, Dosoretz C. Co-metabolic oxidation of pharmaceutical compounds by a nitrifying bacterial enrichment. Bioresour Technol. 2014;167:336-42 pubmed 出版商
Albals D, Hendrickx A, Clincke L, Chankvetadze B, Heyden Y, Mangelings D. A chiral separation strategy for acidic drugs in capillary electrochromatography using both chlorinated and nonchlorinated polysaccharide-based selectors. Electrophoresis. 2014;35:2807-18 pubmed 出版商
Martin J, Santos J, Aparicio I, Alonso E. Pharmaceutically active compounds in sludge stabilization treatments: anaerobic and aerobic digestion, wastewater stabilization ponds and composting. Sci Total Environ. 2015;503-504:97-104 pubmed 出版商
Velásquez G, Santa Cruz L, Espinoza M. Ketoprofen is more effective than diclofenac after oral surgery when used as a preemptive analgesic: a pilot study. J Oral Facial Pain Headache. 2014;28:153-8 pubmed 出版商
Liao L, Liao C, Liu C, Yang T, Wang G. Evaluation of an electrochemical biosensor for uric acid measurement in human whole blood samples. Clin Chim Acta. 2014;436:72-7 pubmed 出版商
Medina J, Padilla A, Hurtado M, Cortés A, Domínguez Ramírez A. In vitro release of ketoprofen suppositories using the USP basket and the flow-through cell dissolution methods. Pak J Pharm Sci. 2014;27:453-8 pubmed
Damulin I. [Treatment of back pain (ketoprofen and other methods)]. Zh Nevrol Psikhiatr Im S S Korsakova. 2014;114:81-6 pubmed
Felton L, Popescu C, Wiley C, Esposito E, Lefevre P, Hopfinger A. Experimental and computational studies of physicochemical properties influence NSAID-cyclodextrin complexation. AAPS PharmSciTech. 2014;15:872-81 pubmed 出版商
Yang G, Yen C, Wang C. Monitoring and removal of residual phthalate esters and pharmaceuticals in the drinking water of Kaohsiung City, Taiwan. J Hazard Mater. 2014;277:53-61 pubmed 出版商
Tamura H, Mori Y, Kaneko H. Organization of local horizontal functional interactions between neurons in the inferior temporal cortex of macaque monkeys. J Neurophysiol. 2014;111:2589-602 pubmed 出版商
Jinno N, Tagashira M, Tsurui K, Yamada S. Contribution of cytochrome P450 and UDT-glucuronosyltransferase to the metabolism of drugs containing carboxylic acid groups: risk assessment of acylglucuronides using human hepatocytes. Xenobiotica. 2014;44:677-86 pubmed 出版商
Pistolozzi M, Fortugno C, Franchini C, Corbo F, Muraglia M, Roy M, et al. Species-dependent binding of tocainide analogues to albumin: affinity chromatography and circular dichroism study. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;968:69-78 pubmed 出版商
Nikumbh K, Sevankar S, Patil M. Formulation development, in vitro and in vivo evaluation of microemulsion-based gel loaded with ketoprofen. Drug Deliv. 2015;22:509-15 pubmed 出版商
Kim J, Bae H, Choi J, Lim J, Kim S, Lee S, et al. Efficacy of gastro-retentive forms of ecabet sodium in the treatment of gastric ulcer in rats. Arch Pharm Res. 2014;37:1053-62 pubmed 出版商
Cilurzo F, Gennari C, Selmin F, Franzé S, Musazzi U, Minghetti P. On the characterization of medicated plasters containing NSAIDs according to novel indications of USP and EMA: adhesive property and in vitro skin permeation studies. Drug Dev Ind Pharm. 2015;41:183-9 pubmed 出版商
Ozguney I, Kardhiqi A. Properties of bioadhesive ketoprofen liquid suppositories: preparation, determination of gelation temperature, viscosity studies and evaluation of mechanical properties using texture analyzer by 4 × 4 factorial design. Pharm Dev Technol. 2014;19:968-75 pubmed 出版商
Ray R, Mujtaba S, Dwivedi A, Yadav N, Verma A, Kushwaha H, et al. Singlet oxygen mediated DNA damage induced phototoxicity by ketoprofen resulting in mitochondrial depolarization and lysosomal destabilization. Toxicology. 2013;314:229-37 pubmed 出版商
Ozguney I, Kardhiqi A, Yıldız G, Ertan G. In vitro-in vivo evaluation of in situ gelling and thermosensitive ketoprofen liquid suppositories. Eur J Drug Metab Pharmacokinet. 2014;39:283-91 pubmed 出版商
Asirvatham Jeyaraj N, King A, Northcott C, Madan S, Fink G. Cyclooxygenase-1 inhibition attenuates angiotensin II-salt hypertension and neurogenic pressor activity in the rat. Am J Physiol Heart Circ Physiol. 2013;305:H1462-70 pubmed 出版商
Benelli E, Massaro M, Norbedo S, Carbone M, Barbi E, Ventura A. An unusual cause of torticollis. J Pediatr. 2013;163:1523.e1 pubmed 出版商
Souza J, Meira A, Volpato N, Mayorga P, Gottfried C. Effect of phonophoresis on skin permeation of commercial anti-inflammatory gels: sodium diclofenac and ketoprofen. Ultrasound Med Biol. 2013;39:1623-30 pubmed 出版商
Sarzi Puttini P, Atzeni F, Lanata L, Bagnasco M. Efficacy of ketoprofen vs. ibuprofen and diclofenac: a systematic review of the literature and meta-analysis. Clin Exp Rheumatol. 2013;31:731-8 pubmed
Conaghan P, Dickson J, Bolten W, Cevc G, Rother M. A multicentre, randomized, placebo- and active-controlled trial comparing the efficacy and safety of topical ketoprofen in Transfersome gel (IDEA-033) with ketoprofen-free vehicle (TDT 064) and oral celecoxib for knee pain associated with osteoarthri. Rheumatology (Oxford). 2013;52:1303-12 pubmed 出版商
Trubetskaia E, Boiko A, Khozova A, Kamchatnov P, Petrov S, Otcheskaia O, et al. [Efficacy of ketoprofen lysine salt (artrosilene) in the treatment of nonspecific vertebrogenic pain syndromes in outpatients]. Zh Nevrol Psikhiatr Im S S Korsakova. 2013;113:53-5 pubmed
Yuan Z, Ye Y, Gao F, Yuan H, Lan M, Lou K, et al. Chitosan-graft-β-cyclodextrin nanoparticles as a carrier for controlled drug release. Int J Pharm. 2013;446:191-8 pubmed 出版商
Duan Y, Meng X, Wen Z, Ke R, Chen L. Multi-phase partitioning, ecological risk and fate of acidic pharmaceuticals in a wastewater receiving river: the role of colloids. Sci Total Environ. 2013;447:267-73 pubmed 出版商
Tunali Y, Akçil E, Dilmen O, Tutuncu A, Koksal G, Akbas S, et al. Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery. J Neurosurg Anesthesiol. 2013;25:143-7 pubmed 出版商
Irisson E, Kerbaul F, Parratte S, Hemon Y, Argenson J, Rosencher N, et al. [Perioperative management based on kinetics of bleeding during total primary arthroplasty]. Ann Fr Anesth Reanim. 2013;32:170-4 pubmed 出版商
Newby N, Pearl D, LeBlanc S, Leslie K, von Keyserlingk M, Duffield T. The effect of administering ketoprofen on the physiology and behavior of dairy cows following surgery to correct a left displaced abomasum. J Dairy Sci. 2013;96:1511-20 pubmed 出版商
Shientag L, Wheeler S, Garlick D, Maranda L. A therapeutic dose of ketoprofen causes acute gastrointestinal bleeding, erosions, and ulcers in rats. J Am Assoc Lab Anim Sci. 2012;51:832-41 pubmed
Fujii S, Hayashi H, Itoh K, Yamada S, Deguchi Y, Kawazu K. Characterization of the carrier-mediated transport of ketoprofen, a nonsteroidal anti-inflammatory drug, in rabbit corneal epithelium cells. J Pharm Pharmacol. 2013;65:171-80 pubmed 出版商
Khan I, Serra C, Anton N, Vandamme T. Continuous-flow encapsulation of ketoprofen in copolymer microbeads via co-axial microfluidic device: influence of operating and material parameters on drug carrier properties. Int J Pharm. 2013;441:809-17 pubmed 出版商
Xu J, Zhu L, Xu G, Yu W, Ray A. Determination of competitive adsorption isotherm of enantiomers on preparative chromatographic columns using inverse method. J Chromatogr A. 2013;1273:49-56 pubmed 出版商
Barulin A, Kurushina O. [Complex therapy of acute and chronic back pain with dexalgin]. Zh Nevrol Psikhiatr Im S S Korsakova. 2012;112:61-4 pubmed
Majewska M, Kołodziej M, Szponar J, Drelich G, Danielewicz P, Kostek H. [Noncardiogenic pulmonary edema in the course of poisoning with clozapine, ketoprofen and thiethylperazine]. Przegl Lek. 2012;69:618-20 pubmed
Lubelska K, Milczarek M, Modzelewska K, Krzyszton Russjan J, Fronczyk K, Wiktorska K. Interactions between drugs and sulforaphane modulate the drug metabolism enzymatic system. Pharmacol Rep. 2012;64:1243-52 pubmed
Su T, Ma J, Li M, Guan X, Yu L, Phillips D. Time-resolved spectroscopic study of the photochemistry of tiaprofenic acid in a neutral phosphate buffered aqueous solution from femtoseconds to final products. J Phys Chem B. 2013;117:811-24 pubmed 出版商
Ozer A, Erhan O, Keles E, Demirel I, Bestas A, Gunduz G. Comparison of the effects of preoperative and intraoperative intravenous application of dexketoprofen on postoperative analgesia in septorhinoplasty patients: randomised double blind clinical trial. Eur Rev Med Pharmacol Sci. 2012;16:1828-33 pubmed
Anneken J, Cunningham J, Collins S, Yamamoto B, Gudelsky G. MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase. J Neuroimmune Pharmacol. 2013;8:58-65 pubmed 出版商
Salgado R, Pereira V, Carvalho G, Soeiro R, Gaffney V, Almeida C, et al. Photodegradation kinetics and transformation products of ketoprofen, diclofenac and atenolol in pure water and treated wastewater. J Hazard Mater. 2013;244-245:516-27 pubmed 出版商
Conti R, Bassi A, Difonzo E, Moretti S, Francalanci S. A case of photoallergic contact dermatitis caused by unusual exposure to ketoprofen. Dermatitis. 2012;23:295-6 pubmed 出版商
Elmorsi Y, El Haggar S, Ibrahim O, Mabrouk M. Effect of ketoprofen and indomethacin on methotrexate pharmacokinetics in mice plasma and tumor tissues. Eur J Drug Metab Pharmacokinet. 2013;38:27-32 pubmed 出版商
Gaudio P, Auriemma G, Mencherini T, Porta G, Reverchon E, Aquino R. Design of alginate-based aerogel for nonsteroidal anti-inflammatory drugs controlled delivery systems using prilling and supercritical-assisted drying. J Pharm Sci. 2013;102:185-94 pubmed 出版商
Brogliato A, Antunes C, Carvalho R, Monteiro A, Tinoco R, Bozza M, et al. Ketoprofen impairs immunosuppression induced by severe sepsis and reveals an important role for prostaglandin E2. Shock. 2012;38:620-9 pubmed 出版商
El Toni A, Khan A, Ibrahim M, Al Hoshan M, Labis J. Fabrication of mesoporous silica shells on solid silica spheres using anionic surfactants and their potential application in controlling drug release. Molecules. 2012;17:13199-210 pubmed 出版商
Yu D, Wang X, Li X, Chian W, Li Y, Liao Y. Electrospun biphasic drug release polyvinylpyrrolidone/ethyl cellulose core/sheath nanofibers. Acta Biomater. 2013;9:5665-72 pubmed 出版商
Mazzocchi A, Montanaro F. Observational study of the use of Symphytum 5CH in the management of pain and swelling after dental implant surgery. Homeopathy. 2012;101:211-6 pubmed 出版商
Fischer S, Parmentier J, Buckley S, Reimold I, Brandl M, Fricker G. Oral bioavailability of ketoprofen in suspension and solution formulations in rats: the influence of poloxamer 188. J Pharm Pharmacol. 2012;64:1631-7 pubmed 出版商
Lehman P, Raney S. In vitro percutaneous absorption of ketoprofen and testosterone: comparison of pluronic lecithin organogel vs. pentravan cream. Int J Pharm Compd. 2012;16:248-52 pubmed
Macocinschi D, Filip D, Vlad S, Butnaru M, Knieling L. Evaluation of polyurethane based on cellulose derivative-ketoprofen biosystem for implant biomedical devices. Int J Biol Macromol. 2013;52:32-7 pubmed 出版商
Degim I, Kadioglu D. Cheap, suitable, predictable and manageable nanoparticles for drug delivery: quantum dots. Curr Drug Deliv. 2013;10:32-8 pubmed
Northrop N, Yamamoto B. Persistent neuroinflammatory effects of serial exposure to stress and methamphetamine on the blood-brain barrier. J Neuroimmune Pharmacol. 2012;7:951-68 pubmed 出版商
Shohin I, Kulinich J, Ramenskaya G, Abrahamsson B, Kopp S, Langguth P, et al. Biowaiver monographs for immediate-release solid oral dosage forms: ketoprofen. J Pharm Sci. 2012;101:3593-603 pubmed 出版商
Gigante A, Tagarro I. Non-steroidal anti-inflammatory drugs and gastroprotection with proton pump inhibitors: a focus on ketoprofen/omeprazole. Clin Drug Investig. 2012;32:221-33 pubmed 出版商
Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W. Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS Comput Biol. 2011;7:e1002310 pubmed 出版商
Christiansen E, Urban C, Grundmann M, Due Hansen M, Hagesaether E, Schmidt J, et al. Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties. J Med Chem. 2011;54:6691-703 pubmed 出版商
Coaccioli S. Ketoprofen 2.5% gel: a clinical overview. Eur Rev Med Pharmacol Sci. 2011;15:943-9 pubmed
Adachi H, Ioppolo F, Paoloni M, Santilli V. Physical characteristics, pharmacological properties and clinical efficacy of the ketoprofen patch: a new patch formulation. Eur Rev Med Pharmacol Sci. 2011;15:823-30 pubmed
Liu M, Yuan M, Li Z, Cheng Y, Luo H, Hu X. Structural investigation into the inhibitory mechanisms of indomethacin and its analogues towards human glyoxalase I. Bioorg Med Chem Lett. 2011;21:4243-7 pubmed 出版商
Gozalbes R, Jacewicz M, Annand R, Tsaioun K, Pineda Lucena A. QSAR-based permeability model for drug-like compounds. Bioorg Med Chem. 2011;19:2615-24 pubmed 出版商
Yuan M, Luo M, Song Y, Xu Q, Wang X, Cao Y, et al. Identification of curcumin derivatives as human glyoxalase I inhibitors: A combination of biological evaluation, molecular docking, 3D-QSAR and molecular dynamics simulation studies. Bioorg Med Chem. 2011;19:1189-96 pubmed 出版商
Talevi A, Goodarzi M, Ortiz E, Duchowicz P, Bellera C, Pesce G, et al. Prediction of drug intestinal absorption by new linear and non-linear QSPR. Eur J Med Chem. 2011;46:218-28 pubmed 出版商
Sarzi Puttini P, Atzeni F, Lanata L, Bagnasco M, Colombo M, Fischer F, et al. Pain and ketoprofen: what is its role in clinical practice?. Reumatismo. 2010;62:172-88 pubmed
Buttar D, Colclough N, Gerhardt S, Macfaul P, Phillips S, Plowright A, et al. A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions. Bioorg Med Chem. 2010;18:7486-96 pubmed 出版商
Ekins S, Williams A, Xu J. A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug Metab Dispos. 2010;38:2302-8 pubmed 出版商
Gozalbes R, Pineda Lucena A. QSAR-based solubility model for drug-like compounds. Bioorg Med Chem. 2010;18:7078-84 pubmed 出版商
Kokki H. Ketoprofen pharmacokinetics, efficacy, and tolerability in pediatric patients. Paediatr Drugs. 2010;12:313-29 pubmed 出版商
Greene N, Fisk L, Naven R, Note R, Patel M, Pelletier D. Developing structure-activity relationships for the prediction of hepatotoxicity. Chem Res Toxicol. 2010;23:1215-22 pubmed 出版商
Avdeef A, Tam K. How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?. J Med Chem. 2010;53:3566-84 pubmed 出版商
Prado Prado F, Garcia Mera X, González Díaz H. Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorg Med Chem. 2010;18:2225-2231 pubmed 出版商
Varma M, Obach R, Rotter C, Miller H, Chang G, Steyn S, et al. Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. J Med Chem. 2010;53:1098-108 pubmed 出版商
Guerra A, Campillo N, Paez J. Neural computational prediction of oral drug absorption based on CODES 2D descriptors. Eur J Med Chem. 2010;45:930-40 pubmed 出版商
Fourches D, Barnes J, Day N, Bradley P, Reed J, Tropsha A. Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chem Res Toxicol. 2010;23:171-83 pubmed 出版商
Lee P, Conradi R, Shanmugasundaram V. Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay. Bioorg Med Chem Lett. 2010;20:69-73 pubmed 出版商
Cantisani C, Grieco T, Faina V, Mattozzi C, Bohnenberger H, Silvestri E, et al. Ketoprofen allergic reactions. Recent Pat Inflamm Allergy Drug Discov. 2010;4:58-64 pubmed
Barden J, Derry S, McQuay H, Moore R. Single dose oral ketoprofen and dexketoprofen for acute postoperative pain in adults. Cochrane Database Syst Rev. 2009;:CD007355 pubmed 出版商
Du Cuny L, Song Z, Moses S, Powis G, Mash E, Meuillet E, et al. Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorg Med Chem. 2009;17:6983-92 pubmed 出版商
Sui X, Sun J, Li H, Wang Y, Liu J, Liu X, et al. Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. Eur J Med Chem. 2009;44:4455-60 pubmed 出版商
Varma M, Feng B, Obach R, Troutman M, Chupka J, Miller H, et al. Physicochemical determinants of human renal clearance. J Med Chem. 2009;52:4844-52 pubmed 出版商
Dreassi E, Zizzari A, Falchi F, Schenone S, Santucci A, Maga G, et al. Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data. Eur J Med Chem. 2009;44:3712-7 pubmed 出版商
Pérez Garrido A, Morales Helguera A, Abellán Guillén A, Cordeiro M, Garrido Escudero A. Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins. Bioorg Med Chem. 2009;17:896-904 pubmed 出版商
Sinning C, Watzer B, Coste O, Nusing R, Ott I, Ligresti A, et al. New analgesics synthetically derived from the paracetamol metabolite N-(4-hydroxyphenyl)-(5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-enamide. J Med Chem. 2008;51:7800-5 pubmed 出版商
Bey E, Marchais Oberwinkler S, Werth R, Negri M, Al Soud Y, Kruchten P, et al. Design, synthesis, biological evaluation and pharmacokinetics of bis(hydroxyphenyl) substituted azoles, thiophenes, benzenes, and aza-benzenes as potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1). J Med Chem. 2008;51:6725-39 pubmed 出版商
Ahlin G, Karlsson J, Pedersen J, Gustavsson L, Larsson R, Matsson P, et al. Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. J Med Chem. 2008;51:5932-42 pubmed 出版商
Li H, Sun J, Sui X, Liu J, Yan Z, Liu X, et al. First-principle, structure-based prediction of hepatic metabolic clearance values in human. Eur J Med Chem. 2009;44:1600-6 pubmed 出版商
Bézière N, Goossens L, Pommery J, Vezin H, Touati N, Henichart J, et al. New NSAIDs-NO hybrid molecules with antiproliferative properties on human prostatic cancer cell lines. Bioorg Med Chem Lett. 2008;18:4655-7 pubmed 出版商
Brunskole M, Stefane B, Zorko K, Anderluh M, Stojan J, Lanisnik Rizner T, et al. Towards the first inhibitors of trihydroxynaphthalene reductase from Curvularia lunata: synthesis of artificial substrate, homology modelling and initial screening. Bioorg Med Chem. 2008;16:5881-9 pubmed 出版商
Pedersen J, Matsson P, Bergström C, Norinder U, Hoogstraate J, Artursson P. Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). J Med Chem. 2008;51:3275-87 pubmed 出版商
Obach R, Lombardo F, Waters N. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug Metab Dispos. 2008;36:1385-405 pubmed 出版商
Wassvik C, Holmén A, Draheim R, Artursson P, Bergström C. Molecular characteristics for solid-state limited solubility. J Med Chem. 2008;51:3035-9 pubmed 出版商
Baert B, Deconinck E, Van Gele M, Slodicka M, Stoppie P, Bodé S, et al. Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorg Med Chem. 2007;15:6943-55 pubmed
Fujikawa M, Nakao K, Shimizu R, Akamatsu M. QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorg Med Chem. 2007;15:3756-67 pubmed
Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed
Ottaviani G, Martel S, Carrupt P. In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities. J Med Chem. 2007;50:742-8 pubmed
Ottaviani G, Martel S, Carrupt P. Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability. J Med Chem. 2006;49:3948-54 pubmed
Voets M, Antes I, Scherer C, Muller Vieira U, Biemel K, Marchais Oberwinkler S, et al. Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis. J Med Chem. 2006;49:2222-31 pubmed
Kumpulainen H, Mähönen N, Laitinen M, Jaurakkajärvi M, Raunio H, Juvonen R, et al. Evaluation of hydroxyimine as cytochrome P450-selective prodrug structure. J Med Chem. 2006;49:1207-11 pubmed
Mazieres B. Topical ketoprofen patch. Drugs R D. 2005;6:337-44 pubmed
Gobec S, Brozic P, Rizner T. Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents. Bioorg Med Chem Lett. 2005;15:5170-5 pubmed
Allegretti M, Bertini R, Cesta M, Bizzarri C, Di Bitondo R, Di Cioccio V, et al. 2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors. J Med Chem. 2005;48:4312-31 pubmed
Caron G, Ermondi G. Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). J Med Chem. 2005;48:3269-79 pubmed
Aureli L, Cruciani G, Cesta M, Anacardio R, De Simone L, Moriconi A. Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach. J Med Chem. 2005;48:2469-79 pubmed
Kiang T, Ensom M, Chang T. UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacol Ther. 2005;106:97-132 pubmed
Mullangi R, Yao M, Srinivas N. Resolution of enantiomers of ketoprofen by HPLC: a review. Biomed Chromatogr. 2003;17:423-34 pubmed
Ouchi A, Zandomeneghi G, Zandomeneghi M. Complexation with albumins of chiral aromatic substrates and their chemistry in ground and excited states. Catalytic and chirality recognition properties of the protein in the cases of binaphthol, its photoisomers, and ketoprofen. Chirality. 2002;14:1-11 pubmed
Saso L, Valentini G, Casini M, Grippa E, Gatto M, Leone M, et al. Inhibition of heat-induced denaturation of albumin by nonsteroidal antiinflammatory drugs (NSAIDs): pharmacological implications. Arch Pharm Res. 2001;24:150-8 pubmed
Milpied Homsi B. [Allergies to ketoprofen gels]. Presse Med. 2001;30:605-9 pubmed
Sugiura M, Hayakawa R, Kato Y, Sugiura K, Ueda H. 4 cases of photocontact dermatitis due to ketoprofen. Contact Dermatitis. 2000;43:16-9 pubmed
Bagheri H, Lhiaubet V, Montastruc J, Chouini Lalanne N. Photosensitivity to ketoprofen: mechanisms and pharmacoepidemiological data. Drug Saf. 2000;22:339-49 pubmed
Schumacher H. Ketoprofen extended-release capsules: a new formulation for the treatment of osteoarthritis and rheumatoid arthritis. Clin Ther. 1994;16:145-59 pubmed
Jamali F, Brocks D. Clinical pharmacokinetics of ketoprofen and its enantiomers. Clin Pharmacokinet. 1990;19:197-217 pubmed
Veys E. 20 years' experience with ketoprofen. Scand J Rheumatol Suppl. 1991;90:Suppl 1-44 pubmed
Serrano G, Fortea J, Latasa J, Millan F, Janes C, Bosca F, et al. Photosensitivity induced by fibric acid derivatives and its relation to photocontact dermatitis to ketoprofen. J Am Acad Dermatol. 1992;27:204-8 pubmed
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