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产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
FLUKA, Sigma-Aldrich, Roche Applied Science
产品类型 :
蛋白
产品名称 :
D-荧光素
目录 :
L9504
文章摘录数: 356
参考文献
Hossain M, Larrous F, Rawlinson S, Zhan J, Sethi A, Ibrahim Y, et al. Structural Elucidation of Viral Antagonism of Innate Immunity at the STAT1 Interface. Cell Rep. 2019;29:1934-1945.e8 pubmed 出版商
Kenny T, Craig A, Villanueva A, Germain D. Mitohormesis Primes Tumor Invasion and Metastasis. Cell Rep. 2019;27:2292-2303.e6 pubmed 出版商
Hu B, Jiang Z, Wang W, Qiu Y, Zhang Z, Liu Y, et al. Nitrate-NRT1.1B-SPX4 cascade integrates nitrogen and phosphorus signalling networks in plants. Nat Plants. 2019;5:401-413 pubmed 出版商
Cheruiyot A, Li S, Nickless A, Roth R, Fitzpatrick J, You Z. Compound C inhibits nonsense-mediated RNA decay independently of AMPK. PLoS ONE. 2018;13:e0204978 pubmed 出版商
Sonnen K, Lauschke V, Uraji J, Falk H, Petersen Y, Funk M, et al. Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation. Cell. 2018;172:1079-1090.e12 pubmed 出版商
Marina Perez A, Aquino B, Viviani V, Kobarg J. Use of a special Brazilian red-light emitting railroad worm Luciferase in bioassays of NEK7 protein Kinase and Creatine Kinase. BMC Biochem. 2017;18:12 pubmed 出版商
Brunetti J, Pillozzi S, Falciani C, Depau L, Tenori E, Scali S, et al. Tumor-selective peptide-carrier delivery of Paclitaxel increases in vivo activity of the drug. Sci Rep. 2015;5:17736 pubmed 出版商
Kurnellas M, Ghosn E, Schartner J, Baker J, Rothbard J, Negrin R, et al. Amyloid fibrils activate B-1a lymphocytes to ameliorate inflammatory brain disease. Proc Natl Acad Sci U S A. 2015;112:15016-23 pubmed 出版商
Zhou P, Liu J, Li X, Takahashi Y, Qi F. The Sialic Acid Binding Protein, Hsa, in Streptococcus gordonii DL1 also Mediates Intergeneric Coaggregation with Veillonella Species. PLoS ONE. 2015;10:e0143898 pubmed 出版商
Kim T, Tuerkcan S, Ceballos A, Pratx G. Modular platform for low-light microscopy. Biomed Opt Express. 2015;6:4585-98 pubmed 出版商
Liu R, Zheng H, Li W, Guo Q, He S, Hirasaki Y, et al. Anti-tumor enhancement of Fei-Liu-Ping ointment in combination with celecoxib via cyclooxygenase-2-mediated lung metastatic inflammatory microenvironment in Lewis lung carcinoma xenograft mouse model. J Transl Med. 2015;13:366 pubmed 出版商
Wolfe A, Debeb B, Lacerda L, Larson R, Bambhroliya A, Huang X, et al. Simvastatin prevents triple-negative breast cancer metastasis in pre-clinical models through regulation of FOXO3a. Breast Cancer Res Treat. 2015;154:495-508 pubmed 出版商
Llobet E, Martínez Moliner V, Moranta D, Dahlström K, Regueiro V, Tomás A, et al. Deciphering tissue-induced Klebsiella pneumoniae lipid A structure. Proc Natl Acad Sci U S A. 2015;112:E6369-78 pubmed 出版商
Kidd P, Young M, Siggia E. Temperature compensation and temperature sensation in the circadian clock. Proc Natl Acad Sci U S A. 2015;112:E6284-92 pubmed 出版商
Dicks M, Spencer A, Coughlan L, Bauza K, Gilbert S, Hill A, et al. Differential immunogenicity between HAdV-5 and chimpanzee adenovirus vector ChAdOx1 is independent of fiber and penton RGD loop sequences in mice. Sci Rep. 2015;5:16756 pubmed 出版商
Kirmes I, Szczurek A, Prakash K, Charapitsa I, Heiser C, Musheev M, et al. A transient ischemic environment induces reversible compaction of chromatin. Genome Biol. 2015;16:246 pubmed 出版商
Benedetti E, Antonosante A, d Angelo M, Cristiano L, Galzio R, Destouches D, et al. Nucleolin antagonist triggers autophagic cell death in human glioblastoma primary cells and decreased in vivo tumor growth in orthotopic brain tumor model. Oncotarget. 2015;6:42091-104 pubmed 出版商
Kim M, Lee W, Jeong J, Kim S, Jin W. Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 and PI3K/AKT signaling in breast cancer. Oncotarget. 2015;6:40158-71 pubmed 出版商
Würth R, Tarn K, Jernigan D, Fernandez S, Cristofanilli M, Fatatis A, et al. A Preclinical Model of Inflammatory Breast Cancer to Study the Involvement of CXCR4 and ACKR3 in the Metastatic Process. Transl Oncol. 2015;8:358-67 pubmed 出版商
Stamatakis K, Jimenez Martinez M, Jimenez Segovia A, Chico Calero I, Conde E, Galán Martínez J, et al. Prostaglandins induce early growth response 1 transcription factor mediated microsomal prostaglandin E2 synthase up-regulation for colorectal cancer progression. Oncotarget. 2015;6:39941-59 pubmed 出版商
Galam L, Failla A, Soundararajan R, Lockey R, Kolliputi N. 4-hydroxynonenal regulates mitochondrial function in human small airway epithelial cells. Oncotarget. 2015;6:41508-21 pubmed 出版商
Xie B, Stammes M, van Driel P, Cruz L, Knol Blankevoort V, Löwik M, et al. Necrosis avid near infrared fluorescent cyanines for imaging cell death and their use to monitor therapeutic efficacy in mouse tumor models. Oncotarget. 2015;6:39036-49 pubmed 出版商
Ferreira Teixeira M, Parada B, Rodrigues Santos P, Alves V, Ramalho J, Caramelo F, et al. Functional and molecular characterization of cancer stem-like cells in bladder cancer: a potential signature for muscle-invasive tumors. Oncotarget. 2015;6:36185-201 pubmed 出版商
Spratt D, Evans M, Davis B, Doran M, Lee M, Shah N, et al. Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation. Cancer Res. 2015;75:4688-96 pubmed 出版商
Cai W, Shen F, Feng Z, Chen J, Liu Q, Li E, et al. Downregulation of CDK-8 inhibits colon cancer hepatic metastasis by regulating Wnt/β-catenin pathway. Biomed Pharmacother. 2015;74:153-7 pubmed 出版商
Urata Y, Takeshita F, Tanaka H, Ochiya T, Takimoto M. Targeted Knockdown of the Kinetochore Protein D40/Knl-1 Inhibits Human Cancer in a p53 Status-Independent Manner. Sci Rep. 2015;5:13676 pubmed 出版商
Ridder D, Wenzel J, Müller K, Töllner K, Tong X, Assmann J, et al. Brain endothelial TAK1 and NEMO safeguard the neurovascular unit. J Exp Med. 2015;212:1529-49 pubmed 出版商
Leten C, Trekker J, Struys T, Dresselaers T, Gijsbers R, Vande Velde G, et al. Assessment of bystander killing-mediated therapy of malignant brain tumors using a multimodal imaging approach. Stem Cell Res Ther. 2015;6:163 pubmed 出版商
Porru M, Artuso S, Salvati E, Bianco A, Franceschin M, Diodoro M, et al. Targeting G-Quadruplex DNA Structures by EMICORON Has a Strong Antitumor Efficacy against Advanced Models of Human Colon Cancer. Mol Cancer Ther. 2015;14:2541-51 pubmed 出版商
Katsumi H, Sano J, Nishikawa M, Hanzawa K, Sakane T, Yamamoto A. Molecular Design of Bisphosphonate-Modified Proteins for Efficient Bone Targeting In Vivo. PLoS ONE. 2015;10:e0135966 pubmed 出版商
Sengupta R, Barone A, Marasa J, Taylor S, Jackson E, Warrington N, et al. Novel chemical library screen identifies naturally occurring plant products that specifically disrupt glioblastoma-endothelial cell interactions. Oncotarget. 2015;6:18282-92 pubmed
Muthana M, Kennerley A, Hughes R, Fagnano E, Richardson J, Paul M, et al. Directing cell therapy to anatomic target sites in vivo with magnetic resonance targeting. Nat Commun. 2015;6:8009 pubmed 出版商
Kalra R, Cheung C, Chaudhary A, Prakash J, Kaul S, Wadhwa R. CARF (Collaborator of ARF) overexpression in p53-deficient cells promotes carcinogenesis. Mol Oncol. 2015;9:1877-89 pubmed 出版商
Cossu I, Bottoni G, Loi M, Emionite L, Bartolini A, Di Paolo D, et al. Neuroblastoma-targeted nanocarriers improve drug delivery and penetration, delay tumor growth and abrogate metastatic diffusion. Biomaterials. 2015;68:89-99 pubmed 出版商
Kim J, Jeong Ryu S, Oh K, Ju J, Yeong Jeon J, Nam G, et al. Memory programming in CD8(+) T-cell differentiation is intrinsic and is not determined by CD4 help. Nat Commun. 2015;6:7994 pubmed 出版商
Zhou Z, Qutaish M, Han Z, Schur R, Liu Y, Wilson D, et al. MRI detection of breast cancer micrometastases with a fibronectin-targeting contrast agent. Nat Commun. 2015;6:7984 pubmed 出版商
Mello D, Ramos I, Mesquita F, Brasil G, Rocha N, Takiya C, et al. Adipose Tissue-Derived Mesenchymal Stromal Cells Protect Mice Infected with Trypanosoma cruzi from Cardiac Damage through Modulation of Anti-parasite Immunity. PLoS Negl Trop Dis. 2015;9:e0003945 pubmed 出版商
Stellari F, Bergamini G, Sandri A, Donofrio G, Sorio C, Ruscitti F, et al. In vivo imaging of the lung inflammatory response to Pseudomonas aeruginosa and its modulation by azithromycin. J Transl Med. 2015;13:251 pubmed 出版商
Dende C, Meena J, Nagarajan P, Panda A, Rangarajan P, Padmanaban G. Simultaneously targeting inflammatory response and parasite sequestration in brain to treat Experimental Cerebral Malaria. Sci Rep. 2015;5:12671 pubmed 出版商
PLACENCIO V, Ichimura A, Miyata T, DeClerck Y. Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity. PLoS ONE. 2015;10:e0133786 pubmed 出版商
Mrozik K, Cheong C, Hewett D, Chow A, Blaschuk O, Zannettino A, et al. Therapeutic targeting of N-cadherin is an effective treatment for multiple myeloma. Br J Haematol. 2015;171:387-99 pubmed 出版商
Yahyanejad S, van Hoof S, Theys J, Barbeau L, Granton P, Paesmans K, et al. An image guided small animal radiation therapy platform (SmART) to monitor glioblastoma progression and therapy response. Radiother Oncol. 2015;116:467-72 pubmed 出版商
Han J, Chu J, Keung Chan W, Zhang J, Wang Y, Cohen J, et al. CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells. Sci Rep. 2015;5:11483 pubmed 出版商
Toubai T, Guoqing H, Rossi C, Mathewson N, Oravecz Wilson K, Cummings E, et al. Ikaros deficiency in host hematopoietic cells separates GVL from GVHD after experimental allogeneic hematopoietic cell transplantation. Oncoimmunology. 2015;4:e1016699 pubmed
Nishioka C, Ikezoe T, Yokoyama A. Blockade of CD82 by a monoclonal antibody potentiates anti-leukemia effects of AraC in vivo. Cancer Med. 2015;4:1426-31 pubmed 出版商
Cui Y, Geng Q, Yu T, Zhang F, Lin H, Li J, et al. Establishment of a highly metastatic model with a newly isolated lung adenocarcinoma cell line. Int J Oncol. 2015;47:927-40 pubmed 出版商
Thomas S, Fisher K, Snowden J, Danson S, Brown S, Zeidler M. Methotrexate Is a JAK/STAT Pathway Inhibitor. PLoS ONE. 2015;10:e0130078 pubmed 出版商
Wang M, Crosby A, Hastie E, Samulski J, McPhee S, Joshua G, et al. Prediction of adeno-associated virus neutralizing antibody activity for clinical application. Gene Ther. 2015;22:984-92 pubmed 出版商
Unzu C, Melero I, Hervas Stubbs S, Sampedro A, Mancheno U, Morales Kastresana A, et al. Helper-dependent adenovirus achieve more efficient and persistent liver transgene expression in non-human primates under immunosuppression. Gene Ther. 2015;22:856-65 pubmed 出版商
Finlay J, Roberts C, Dong J, Zink J, Tamanoi F, Glackin C. Mesoporous silica nanoparticle delivery of chemically modified siRNA against TWIST1 leads to reduced tumor burden. Nanomedicine. 2015;11:1657-66 pubmed 出版商
Kandela I, Jin H, Owen K. Registered report: BET bromodomain inhibition as a therapeutic strategy to target c-Myc. elife. 2015;4:e07072 pubmed 出版商
ToruÅ„ A, SzymaÅ„ska E, Castanon I, WoliÅ„ska NizioÅ‚ L, Bartosik A, JastrzÄ™bski K, et al. Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling. PLoS ONE. 2015;10:e0130818 pubmed 出版商
Song D, Ye Q, Poussin M, Liu L, Figini M, Powell D. A fully human chimeric antigen receptor with potent activity against cancer cells but reduced risk for off-tumor toxicity. Oncotarget. 2015;6:21533-46 pubmed
Goda K, Hatta Ohashi Y, Akiyoshi R, Sugiyama T, Sakai I, Takahashi T, et al. Combining fluorescence and bioluminescence microscopy. Microsc Res Tech. 2015;78:715-22 pubmed 出版商
Hatano M, Matsumoto Y, Fukushi J, Matsunobu T, Endo M, Okada S, et al. Cadherin-11 regulates the metastasis of Ewing sarcoma cells to bone. Clin Exp Metastasis. 2015;32:579-91 pubmed 出版商
Kinnear E, Caproni L, Tregoning J. A Comparison of Red Fluorescent Proteins to Model DNA Vaccine Expression by Whole Animal In Vivo Imaging. PLoS ONE. 2015;10:e0130375 pubmed 出版商
Kutty R, Chia S, Setyawati M, Muthu M, Feng S, Leong D. In vivo and ex vivo proofs of concept that cetuximab conjugated vitamin E TPGS micelles increases efficacy of delivered docetaxel against triple negative breast cancer. Biomaterials. 2015;63:58-69 pubmed 出版商
Yang H, Pellegrini L, Napolitano A, Giorgi C, Jube S, Preti A, et al. Aspirin delays mesothelioma growth by inhibiting HMGB1-mediated tumor progression. Cell Death Dis. 2015;6:e1786 pubmed 出版商
Castro N, Fedorova Abrams N, Merchant A, Rangel M, Nagaoka T, Karasawa H, et al. Cripto-1 as a novel therapeutic target for triple negative breast cancer. Oncotarget. 2015;6:11910-29 pubmed
Takano S, Tomita J, Sonoike K, Iwasaki H. The initiation of nocturnal dormancy in Synechococcus as an active process. BMC Biol. 2015;13:36 pubmed 出版商
Kim J, Kane J, Young J, Chang A, Kanojia D, Morshed R, et al. A Genetically Modified Adenoviral Vector with a Phage Display-Derived Peptide Incorporated into Fiber Fibritin Chimera Prolongs Survival in Experimental Glioma. Hum Gene Ther. 2015;26:635-46 pubmed 出版商
Yoshimura Y, Nakamura K, Endo T, Kajitani N, Kazuki K, Kazuki Y, et al. Mouse embryonic stem cells with a multi-integrase mouse artificial chromosome for transchromosomic mouse generation. Transgenic Res. 2015;24:717-27 pubmed 出版商
Helmfors H, Eriksson J, Langel Ã. Optimized luciferase assay for cell-penetrating peptide-mediated delivery of short oligonucleotides. Anal Biochem. 2015;484:136-42 pubmed 出版商
Qin H, Cho M, Haso W, Zhang L, Tasian S, Oo H, et al. Eradication of B-ALL using chimeric antigen receptor-expressing T cells targeting the TSLPR oncoprotein. Blood. 2015;126:629-39 pubmed 出版商
Jia F, Wang C, Huang J, Yang G, Wu C, Zheng C. SCF E3 ligase PP2-B11 plays a positive role in response to salt stress in Arabidopsis. J Exp Bot. 2015;66:4683-97 pubmed 出版商
Chopra M, Brandl A, Siegmund D, Mottok A, Schäfer V, Biehl M, et al. Blocking TWEAK-Fn14 interaction inhibits hematopoietic stem cell transplantation-induced intestinal cell death and reduces GVHD. Blood. 2015;126:437-44 pubmed 出版商
Bell C, Yu D, Smolke C, Geall A, Beard C, Mason P. Control of alphavirus-based gene expression using engineered riboswitches. Virology. 2015;483:302-11 pubmed 出版商
Kaku Y, Tsuchiya A, Kanno T, Nakano T, Nishizaki T. Diarachidonoylphosphoethanolamine induces necrosis/necroptosis of malignant pleural mesothelioma cells. Cell Signal. 2015;27:1713-9 pubmed 出版商
Fan C, Wang Y, Liu Z, Sun Y, Wang X, Wei G, et al. Metformin exerts anticancer effects through the inhibition of the Sonic hedgehog signaling pathway in breast cancer. Int J Mol Med. 2015;36:204-14 pubmed 出版商
Yao X, Liu Y, Gao J, Yang L, Mao D, Stefanitsch C, et al. Nitric oxide releasing hydrogel enhances the therapeutic efficacy of mesenchymal stem cells for myocardial infarction. Biomaterials. 2015;60:130-40 pubmed 出版商
Feng X, Szulzewsky F, Yerevanian A, Chen Z, Heinzmann D, Rasmussen R, et al. Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis. Oncotarget. 2015;6:15077-94 pubmed
Zhang Z, Wang M, Zhou L, Feng X, Cheng J, Yu Y, et al. Increased HMGB1 and cleaved caspase-3 stimulate the proliferation of tumor cells and are correlated with the poor prognosis in colorectal cancer. J Exp Clin Cancer Res. 2015;34:51 pubmed 出版商
Hwang S, Lee H, Kim H, Song H, Lee D, Lee H, et al. Overexpression of microRNA-95-3p suppresses brain metastasis of lung adenocarcinoma through downregulation of cyclin D1. Oncotarget. 2015;6:20434-48 pubmed
Cheung A, Ip J, Chu A, Cheng Y, Leong M, Ko J, et al. PTPRG suppresses tumor growth and invasion via inhibition of Akt signaling in nasopharyngeal carcinoma. Oncotarget. 2015;6:13434-47 pubmed
Burgos Ojeda D, Wu R, McLean K, Chen Y, Talpaz M, Yoon E, et al. CD24+ Ovarian Cancer Cells Are Enriched for Cancer-Initiating Cells and Dependent on JAK2 Signaling for Growth and Metastasis. Mol Cancer Ther. 2015;14:1717-27 pubmed 出版商
Zhang H, Ma Y, Zhang S, Liu H, He H, Li N, et al. Involvement of Ras GTPase-activating protein SH3 domain-binding protein 1 in the epithelial-to-mesenchymal transition-induced metastasis of breast cancer cells via the Smad signaling pathway. Oncotarget. 2015;6:17039-53 pubmed
Akimoto M, Iizuka M, Kanematsu R, Yoshida M, Takenaga K. Anticancer Effect of Ginger Extract against Pancreatic Cancer Cells Mainly through Reactive Oxygen Species-Mediated Autotic Cell Death. PLoS ONE. 2015;10:e0126605 pubmed 出版商
Zeng Y, Chen C, Liu W, Fu Q, Han Z, Li Y, et al. Injectable microcryogels reinforced alginate encapsulation of mesenchymal stromal cells for leak-proof delivery and alleviation of canine disc degeneration. Biomaterials. 2015;59:53-65 pubmed 出版商
Nyitray C, Chang R, Faleo G, Lance K, Bernards D, Tang Q, et al. Polycaprolactone Thin-Film Micro- and Nanoporous Cell-Encapsulation Devices. ACS Nano. 2015;9:5675-82 pubmed 出版商
Devaud C, Westwood J, Teng M, John L, Yong C, Duong C, et al. Differential potency of regulatory T cell-mediated immunosuppression in kidney tumors compared to subcutaneous tumors. Oncoimmunology. 2014;3:e963395 pubmed
Wang E, Wang L, Tsai C, Bhoj V, Gershenson Z, Moon E, et al. Generation of Potent T-cell Immunotherapy for Cancer Using DAP12-Based, Multichain, Chimeric Immunoreceptors. Cancer Immunol Res. 2015;3:815-26 pubmed 出版商
Takahashi K, Nagai N, Ogura K, Tsuneyama K, Saiki I, Irimura T, et al. Mammary tissue microenvironment determines T cell-dependent breast cancer-associated inflammation. Cancer Sci. 2015;106:867-74 pubmed 出版商
Shin D, Park J, Lee J, Won H, Jang K, Min K, et al. Overexpression of Id1 in transgenic mice promotes mammary basal stem cell activity and breast tumorigenesis. Oncotarget. 2015;6:17276-90 pubmed
Tichet M, Prod homme V, Fenouille N, Ambrosetti D, Mallavialle A, Cerezo M, et al. Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis. Nat Commun. 2015;6:6993 pubmed 出版商
Giannou A, Marazioti A, Spella M, Kanellakis N, Apostolopoulou H, Psallidas I, et al. Mast cells mediate malignant pleural effusion formation. J Clin Invest. 2015;125:2317-34 pubmed 出版商
Butler A, Scotti Buzhardt M, Erdogan E, Li S, Inman K, Fields A, et al. A small molecule inhibitor of atypical protein kinase C signaling inhibits pancreatic cancer cell transformed growth and invasion. Oncotarget. 2015;6:15297-310 pubmed
Gu Y, Zhou H, Gan Y, Zhang J, Chen J, Gan X, et al. Small-molecule induction of phospho-eIF4E sumoylation and degradation via targeting its phosphorylated serine 209 residue. Oncotarget. 2015;6:15111-21 pubmed
Alonso S, Su M, Jones J, Ganguly S, KANE M, Jones R, et al. Human bone marrow niche chemoprotection mediated by cytochrome P450 enzymes. Oncotarget. 2015;6:14905-12 pubmed
Sloves P, Mouveaux T, Ait Yahia S, Vorng H, Everaere L, Sangare L, et al. Apical Organelle Secretion by Toxoplasma Controls Innate and Adaptive Immunity and Mediates Long-Term Protection. J Infect Dis. 2015;212:1449-58 pubmed 出版商
Fritsche H, Heilmann T, Tower R, Hauser C, von Au A, El Sheikh D, et al. TRAIL-R2 promotes skeletal metastasis in a breast cancer xenograft mouse model. Oncotarget. 2015;6:9502-16 pubmed
Ferrigno A, Vairetti M, Ambrosi G, Rizzo V, Richelmi P, Blandini F, et al. Selective blockade of mGlu5 metabotropic glutamate receptors is protective against hepatic mitochondrial dysfunction in 6-OHDA lesioned Parkinsonian rats. Clin Exp Pharmacol Physiol. 2015;42:695-703 pubmed 出版商
Fang X, Song R, Chen W, Yang Y, Gu Y, Shu Y, et al. PRL-3 Promotes the Malignant Progression of Melanoma via Triggering Dephosphorylation and Cytoplasmic Localization of NHERF1. J Invest Dermatol. 2015;135:2273-2282 pubmed 出版商
Gong C, Liu B, Yao Y, Qu S, Luo W, Tan W, et al. Potentiated DNA Damage Response in Circulating Breast Tumor Cells Confers Resistance to Chemotherapy. J Biol Chem. 2015;290:14811-25 pubmed 出版商
Frishman Levy L, Shemesh A, Bar Sinai A, Ma C, Ni Z, Frenkel S, et al. Central nervous system acute lymphoblastic leukemia: role of natural killer cells. Blood. 2015;125:3420-31 pubmed 出版商
Boonstra M, van Driel P, van Willigen D, Stammes M, Prevoo H, Tummers Q, et al. uPAR-targeted multimodal tracer for pre- and intraoperative imaging in cancer surgery. Oncotarget. 2015;6:14260-73 pubmed
An S, Jiang X, Shi J, He X, Li J, Guo Y, et al. Single-component self-assembled RNAi nanoparticles functionalized with tumor-targeting iNGR delivering abundant siRNA for efficient glioma therapy. Biomaterials. 2015;53:330-40 pubmed 出版商
Han D, Huang W, Ma S, Chen J, Gao L, Liu T, et al. Ghrelin improves functional survival of engrafted adipose-derived mesenchymal stem cells in ischemic heart through PI3K/Akt signaling pathway. Biomed Res Int. 2015;2015:858349 pubmed 出版商
Sorokin A, Nair B, Wei Y, Aziz K, Evdokimova V, Hung M, et al. Aberrant Expression of proPTPRN2 in Cancer Cells Confers Resistance to Apoptosis. Cancer Res. 2015;75:1846-58 pubmed 出版商
De Niz M, Helm S, Horstmann S, Annoura T, del Portillo H, Khan S, et al. In vivo and in vitro characterization of a Plasmodium liver stage-specific promoter. PLoS ONE. 2015;10:e0123473 pubmed 出版商
Li X, Lu Y, Lu H, Luo J, Hong Y, Fan Z. AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab. Oncotarget. 2015;6:11507-18 pubmed
Kokate R, Thamake S, Chaudhary P, Mott B, Raut S, Vishwanatha J, et al. Enhancement of anti-tumor effect of particulate vaccine delivery system by 'bacteriomimetic' CpG functionalization of poly-lactic-co-glycolic acid nanoparticles. Nanomedicine (Lond). 2015;10:915-29 pubmed 出版商
Lewis M, Behrends J, Sá E Cunha C, Mendes A, Lasitschka F, Sattler J, et al. Chemical attenuation of Plasmodium in the liver modulates severe malaria disease progression. J Immunol. 2015;194:4860-70 pubmed 出版商
Stevens K, Miller J, Blakely B, Chen C, Bhatia S. Degradable hydrogels derived from PEG-diacrylamide for hepatic tissue engineering. J Biomed Mater Res A. 2015;103:3331-8 pubmed 出版商
Yagishita S, Fujita Y, Kitazono S, Ko R, Nakadate Y, Sawada T, et al. Chemotherapy-Regulated microRNA-125-HER2 Pathway as a Novel Therapeutic Target for Trastuzumab-Mediated Cellular Cytotoxicity in Small Cell Lung Cancer. Mol Cancer Ther. 2015;14:1414-23 pubmed 出版商
Wu S, Zhang J, Huang C, Jia H, Wang Y, Xu Z, et al. Prolyl hydroxylase domain-2 silencing induced by hydrodynamic limb vein injection enhances vascular regeneration in critical limb ischemia mice through activation of multiple genes. Curr Gene Ther. 2015;15:313-25 pubmed
Tavri S, Vezeridis A, Cui W, Mattrey R. In Vivo Transfection and Detection of Gene Expression of Stem Cells Preloaded with DNA-carrying Microbubbles. Radiology. 2015;276:518-25 pubmed 出版商
Klingler S, Guo B, Yao J, Yan H, Zhang L, Vaseva A, et al. Development of Resistance to EGFR-Targeted Therapy in Malignant Glioma Can Occur through EGFR-Dependent and -Independent Mechanisms. Cancer Res. 2015;75:2109-19 pubmed 出版商
Enzo E, Santinon G, Pocaterra A, Aragona M, Bresolin S, Forcato M, et al. Aerobic glycolysis tunes YAP/TAZ transcriptional activity. EMBO J. 2015;34:1349-70 pubmed 出版商
Schneidawind D, Baker J, Pierini A, Buechele C, Luong R, Meyer E, et al. Third-party CD4+ invariant natural killer T cells protect from murine GVHD lethality. Blood. 2015;125:3491-500 pubmed 出版商
Lawler C, Milho R, May J, Stevenson P. Rhadinovirus host entry by co-operative infection. PLoS Pathog. 2015;11:e1004761 pubmed 出版商
Ayzenberg I, Schlevogt S, Metzdorf J, Stahlke S, Pedreitturia X, Hunfeld A, et al. Analysis of neurogenesis during experimental autoimmune encephalomyelitis reveals pitfalls of bioluminescence imaging. PLoS ONE. 2015;10:e0118550 pubmed 出版商
Day P, Thompson C, Lowy D, Schiller J. The HPV16 and MusPV1 papillomaviruses initially interact with distinct host components on the basement membrane. Virology. 2015;481:79-94 pubmed 出版商
Buchner M, Park E, Geng H, Klemm L, Flach J, Passegué E, et al. Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia. Nat Commun. 2015;6:6471 pubmed 出版商
Banerjee D, Hernandez S, Garcia A, Kangsamaksin T, Sbiroli E, Andrews J, et al. Notch suppresses angiogenesis and progression of hepatic metastases. Cancer Res. 2015;75:1592-602 pubmed 出版商
Sagiv Barfi I, Kohrt H, Czerwinski D, Ng P, Chang B, Levy R. Therapeutic antitumor immunity by checkpoint blockade is enhanced by ibrutinib, an inhibitor of both BTK and ITK. Proc Natl Acad Sci U S A. 2015;112:E966-72 pubmed 出版商
Chi B, Kim S, Seo H, Seo H, Lee S, Kwon J, et al. P70S6K and Elf4E dual inhibition is essential to control bladder tumor growth and progression in orthotopic mouse non-muscle invasive bladder tumor model. J Korean Med Sci. 2015;30:308-16 pubmed 出版商
Sag D, Cekic C, Wu R, Linden J, Hedrick C. The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity. Nat Commun. 2015;6:6354 pubmed 出版商
Shuen W, Kan R, Yu Z, Lung H, Lung M. Novel lentiviral-inducible transgene expression systems and versatile single-plasmid reporters for in vitro and in vivo cancer biology studies. Cancer Gene Ther. 2015;22:207-14 pubmed 出版商
Jensen K, Camejo A, Melo M, Cordeiro C, Julien L, Grotenbreg G, et al. Toxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination. MBio. 2015;6:e02280 pubmed 出版商
Ma J, Cheng J, Gong Y, Tian L, Huang Q. Downregulation of Wnt signaling by sonic hedgehog activation promotes repopulation of human tumor cell lines. Dis Model Mech. 2015;8:385-91 pubmed 出版商
Kloos A, Woller N, Gürlevik E, Ureche C, Niemann J, Armbrecht N, et al. PolySia-Specific Retargeting of Oncolytic Viruses Triggers Tumor-Specific Immune Responses and Facilitates Therapy of Disseminated Lung Cancer. Cancer Immunol Res. 2015;3:751-63 pubmed 出版商
Schrauwen S, Coenegrachts L, Depreeuw J, Luyten C, Verbist G, Debruyne D, et al. Microsatellite instable and microsatellite stable primary endometrial carcinoma cells and their subcutaneous and orthotopic xenografts recapitulate the characteristics of the corresponding primary tumor. Int J Gynecol Cancer. 2015;25:363-71 pubmed 出版商
Wang Q, Hardie R, Hoy A, van Geldermalsen M, Gao D, Fazli L, et al. Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development. J Pathol. 2015;236:278-89 pubmed 出版商
Schmittnaegel M, Levitsky V, Hoffmann E, Georges G, Mundigl O, Klein C, et al. Committing Cytomegalovirus-Specific CD8 T Cells to Eliminate Tumor Cells by Bifunctional Major Histocompatibility Class I Antibody Fusion Molecules. Cancer Immunol Res. 2015;3:764-76 pubmed 出版商
Kroesen M, Brok I, Reijnen D, van Hout Kuijer M, Zeelenberg I, den Brok M, et al. Intra-adrenal murine TH-MYCN neuroblastoma tumors grow more aggressive and exhibit a distinct tumor microenvironment relative to their subcutaneous equivalents. Cancer Immunol Immunother. 2015;64:563-72 pubmed 出版商
Sun M, Wang M, Chen M, Dagnaes Hansen F, Le D, Baatrup A, et al. A tissue-engineered therapeutic device inhibits tumor growth in vitro and in vivo. Acta Biomater. 2015;18:21-9 pubmed 出版商
Todeschi M, El Backly R, Capelli C, Daga A, Patrone E, Introna M, et al. Transplanted Umbilical Cord Mesenchymal Stem Cells Modify the In Vivo Microenvironment Enhancing Angiogenesis and Leading to Bone Regeneration. Stem Cells Dev. 2015;24:1570-81 pubmed 出版商
Kalbitz M, Grailer J, Fattahi F, Jajou L, Herron T, Campbell K, et al. Role of extracellular histones in the cardiomyopathy of sepsis. FASEB J. 2015;29:2185-93 pubmed 出版商
Mallinger A, Crumpler S, Pichowicz M, Waalboer D, Stubbs M, Adeniji Popoola O, et al. Discovery of potent, orally bioavailable, small-molecule inhibitors of WNT signaling from a cell-based pathway screen. J Med Chem. 2015;58:1717-35 pubmed 出版商
Yoo K, Jeon J, Ryu S, Nam G, Youn H, Choi E. Subdominant H60 antigen-specific CD8 T-cell response precedes dominant H4 antigen-specific response during the initial phase of allogenic skin graft rejection. Exp Mol Med. 2015;47:e140 pubmed 出版商
Wang N, Rayes R, Elahi S, Lu Y, Hancock M, Massie B, et al. The IGF-Trap: Novel Inhibitor of Carcinoma Growth and Metastasis. Mol Cancer Ther. 2015;14:982-93 pubmed 出版商
Zhang R, Liu T, Senju S, Haruta M, Hirosawa N, Suzuki M, et al. Generation of mouse pluripotent stem cell-derived proliferating myeloid cells as an unlimited source of functional antigen-presenting cells. Cancer Immunol Res. 2015;3:668-77 pubmed 出版商
Münch R, Muth A, Muik A, Friedel T, Schmatz J, Dreier B, et al. Off-target-free gene delivery by affinity-purified receptor-targeted viral vectors. Nat Commun. 2015;6:6246 pubmed 出版商
Jang G, Hong I, Kim R, Lee S, Park S, Lee E, et al. Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells. Cancer Res. 2015;75:1691-702 pubmed 出版商
Besnard A, Guabiraba R, Niedbala W, Palomo J, Reverchon F, Shaw T, et al. IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells. PLoS Pathog. 2015;11:e1004607 pubmed 出版商
Kim P, Mahmoudi M, Ge X, Matsuura Y, Toma I, METZLER S, et al. Direct evaluation of myocardial viability and stem cell engraftment demonstrates salvage of the injured myocardium. Circ Res. 2015;116:e40-50 pubmed 出版商
Burkard C, Verheije M, Haagmans B, van Kuppeveld F, Rottier P, Bosch B, et al. ATP1A1-mediated Src signaling inhibits coronavirus entry into host cells. J Virol. 2015;89:4434-48 pubmed 出版商
Zhang L, Xia L, Zhao L, Chen Z, Shang X, Xin J, et al. Activation of PAX3-MET pathways due to miR-206 loss promotes gastric cancer metastasis. Carcinogenesis. 2015;36:390-9 pubmed 出版商
Arsenault D, Drouin Ouellet J, Saint Pierre M, Petrou P, Dubois M, Kriz J, et al. A novel combinational approach of microstimulation and bioluminescence imaging to study the mechanisms of action of cerebral electrical stimulation in mice. J Physiol. 2015;593:2257-78 pubmed 出版商
Almåsbak H, Walseng E, Kristian A, Myhre M, Suso E, Munthe L, et al. Inclusion of an IgG1-Fc spacer abrogates efficacy of CD19 CAR T cells in a xenograft mouse model. Gene Ther. 2015;22:391-403 pubmed 出版商
Pfeil J, Heine J, Mueller A. Addition of histamine to subcutaneously injected Plasmodium berghei sporozoites increases the parasite liver load and could facilitate whole-parasite vaccination. Malar J. 2015;14:36 pubmed 出版商
Huang F, Lee T, Chang C, Chen L, Hsu W, Chang C, et al. Evaluation of 188Re-labeled PEGylated nanoliposome as a radionuclide therapeutic agent in an orthotopic glioma-bearing rat model. Int J Nanomedicine. 2015;10:463-73 pubmed 出版商
Dai X, Ahn K, Kim C, Siveen K, Ong T, Shanmugam M, et al. Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3. Mol Oncol. 2015;9:818-33 pubmed 出版商
Ju H, Calvisi D, Moon H, Baek S, Ribback S, Dombrowski F, et al. Transgenic mouse model expressing P53(R172H), luciferase, EGFP, and KRAS(G12D) in a single open reading frame for live imaging of tumor. Sci Rep. 2015;5:8053 pubmed 出版商
Wendt M, Williams W, Pascuzzi P, Balanis N, Schiemann B, Carlin C, et al. The antitumorigenic function of EGFR in metastatic breast cancer is regulated by expression of Mig6. Neoplasia. 2015;17:124-33 pubmed 出版商
Banach Orlowska M, Szymańska E, Miaczynska M. APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription. FEBS Lett. 2015;589:532-9 pubmed 出版商
Huang Y, Clarke F, Karimi M, Roy N, Williamson E, Okumura M, et al. CRK proteins selectively regulate T cell migration into inflamed tissues. J Clin Invest. 2015;125:1019-32 pubmed 出版商
Xiao X, Liu Z, Wang R, Wang J, Zhang S, Cai X, et al. Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis. Oncotarget. 2015;6:3225-39 pubmed
MacDuff D, Reese T, Kimmey J, Weiss L, Song C, Zhang X, et al. Phenotypic complementation of genetic immunodeficiency by chronic herpesvirus infection. elife. 2015;4: pubmed 出版商
Rajgopal A, Rebhun J, Burns C, Scholten J, Balles J, Fast D. Immunomodulatory effects of Lippia sidoides extract: induction of IL-10 through cAMP and p38 MAPK-dependent mechanisms. J Med Food. 2015;18:370-7 pubmed 出版商
Tsai C, Lin L, Wang C, Chiu Y, Chou Y, Chiu S, et al. Over-expression of cofilin-1 suppressed growth and invasion of cancer cells is associated with up-regulation of let-7 microRNA. Biochim Biophys Acta. 2015;1852:851-61 pubmed 出版商
Fujita Y, Yagishita S, Hagiwara K, Yoshioka Y, Kosaka N, Takeshita F, et al. The clinical relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 network in chemoresistant non-small-cell lung cancer. Mol Ther. 2015;23:717-27 pubmed 出版商
Fujita Y, Yagishita S, Takeshita F, Yamamoto Y, Kuwano K, Ochiya T. Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer. Oncotarget. 2015;6:3335-45 pubmed
Zaitseva M, McCullough K, Cruz S, Thomas A, Diaz C, Keilholz L, et al. Postchallenge administration of brincidofovir protects healthy and immune-deficient mice reconstituted with limited numbers of T cells from lethal challenge with IHD-J-Luc vaccinia virus. J Virol. 2015;89:3295-307 pubmed 出版商
Pandey P, Rachagani S, Das S, Seshacharyulu P, Sheinin Y, Naslavsky N, et al. Amyloid precursor-like protein 2 (APLP2) affects the actin cytoskeleton and increases pancreatic cancer growth and metastasis. Oncotarget. 2015;6:2064-75 pubmed
Rudolph D, Impagnatiello M, Blaukopf C, Sommer C, Gerlich D, Roth M, et al. Efficacy and mechanism of action of volasertib, a potent and selective inhibitor of Polo-like kinases, in preclinical models of acute myeloid leukemia. J Pharmacol Exp Ther. 2015;352:579-89 pubmed 出版商
Nouri F, Wang X, Hatefi A. Genetically engineered theranostic mesenchymal stem cells for the evaluation of the anticancer efficacy of enzyme/prodrug systems. J Control Release. 2015;200:179-87 pubmed 出版商
Li C, Meng G, Su L, Chen A, Xia M, Xu C, et al. Dichloroacetate blocks aerobic glycolytic adaptation to attenuated measles virus and promotes viral replication leading to enhanced oncolysis in glioblastoma. Oncotarget. 2015;6:1544-55 pubmed
Ran L, Sirota I, Cao Z, Murphy D, Chen Y, Shukla S, et al. Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth. Cancer Discov. 2015;5:304-15 pubmed 出版商
Lee S, Jeon T, Biswal S. Effect of local treatment with adipose tissue-derived mesenchymal stem cells in the early tumorigenesis of osteosarcoma. Oncol Rep. 2015;33:1381-7 pubmed 出版商
Della Peruta M, Badar A, Rosales C, Chokshi S, Kia A, Nathwani D, et al. Preferential targeting of disseminated liver tumors using a recombinant adeno-associated viral vector. Hum Gene Ther. 2015;26:94-103 pubmed 出版商
Al Faraj A, Shaik A, Shaik A. Magnetic single-walled carbon nanotubes as efficient drug delivery nanocarriers in breast cancer murine model: noninvasive monitoring using diffusion-weighted magnetic resonance imaging as sensitive imaging biomarker. Int J Nanomedicine. 2015;10:157-68 pubmed 出版商
Tronik Le Roux D, Nicola M, Vaigot P, Nurden P. Single thrombopoietin dose alleviates hematopoietic stem cells intrinsic short- and long-term ionizing radiation damage. In vivo identification of anatomical cell expansion sites. Radiat Res. 2015;183:52-63 pubmed 出版商
Wagenaar T, Tolstykh T, Shi C, Jiang L, Zhang J, Li Z, et al. Identification of the endosomal sorting complex required for transport-I (ESCRT-I) as an important modulator of anti-miR uptake by cancer cells. Nucleic Acids Res. 2015;43:1204-15 pubmed 出版商
Adinolfi E, Capece M, Franceschini A, Falzoni S, Giuliani A, Rotondo A, et al. Accelerated tumor progression in mice lacking the ATP receptor P2X7. Cancer Res. 2015;75:635-44 pubmed 出版商
Schneider C, Perez J, CHENG E, Zhang C, Mastorakos P, Hanes J, et al. Minimizing the non-specific binding of nanoparticles to the brain enables active targeting of Fn14-positive glioblastoma cells. Biomaterials. 2015;42:42-51 pubmed 出版商
Wong C, Au S, Tse A, Xu I, Lai R, Chiu D, et al. Switching of pyruvate kinase isoform L to M2 promotes metabolic reprogramming in hepatocarcinogenesis. PLoS ONE. 2014;9:e115036 pubmed 出版商
Li Y, Reader J, Ma X, Kundu N, Kochel T, Fulton A. Divergent roles of CXCR3 isoforms in promoting cancer stem-like cell survival and metastasis. Breast Cancer Res Treat. 2015;149:403-15 pubmed 出版商
Li Y, Chen H, Bannick N, Henry M, Holm A, Metwali A, et al. Intestinal helminths regulate lethal acute graft-versus-host disease and preserve the graft-versus-tumor effect in mice. J Immunol. 2015;194:1011-20 pubmed 出版商
Winiarska M, Bojarczuk K, Pyrzynska B, Bil J, Siernicka M, Dwojak M, et al. Inhibitors of SRC kinases impair antitumor activity of anti-CD20 monoclonal antibodies. MAbs. 2014;6:1300-13 pubmed 出版商
Chen J, Lee H, Wu X, Huo L, Kim S, Xu L, et al. Gain of glucose-independent growth upon metastasis of breast cancer cells to the brain. Cancer Res. 2015;75:554-65 pubmed 出版商
Du Z, Zan T, Huang X, Sheng L, Li H, Li H, et al. DFO enhances the targeting of CD34-positive cells and improves neovascularization. Cell Transplant. 2015;24:2353-66 pubmed 出版商
Kwon S, Lee S, Na J, Lee S, Lee H, Park J, et al. Targeting BRG1 chromatin remodeler via its bromodomain for enhanced tumor cell radiosensitivity in vitro and in vivo. Mol Cancer Ther. 2015;14:597-607 pubmed 出版商
Zinonos I, Labrinidis A, Liapis V, Hay S, Panagopoulos V, DeNichilo M, et al. Doxorubicin overcomes resistance to drozitumab by antagonizing Inhibitor of Apoptosis Proteins (IAPs). Anticancer Res. 2014;34:7007-20 pubmed
Tsang C, Cheung K, Cheung Y, Man K, Lui V, Tsao S, et al. Berberine suppresses Id-1 expression and inhibits the growth and development of lung metastases in hepatocellular carcinoma. Biochim Biophys Acta. 2015;1852:541-51 pubmed 出版商
Kriisa M, Sinijärv H, Vaasa A, Enkvist E, Kostenko S, Moens U, et al. Inhibition of CREB phosphorylation by conjugates of adenosine analogues and arginine-rich peptides, inhibitors of PKA catalytic subunit. Chembiochem. 2015;16:312-9 pubmed 出版商
Tarasewicz E, Rivas L, Hamdan R, Dokic D, Parimi V, Bernabé B, et al. Inhibition of CDK-mediated phosphorylation of Smad3 results in decreased oncogenesis in triple negative breast cancer cells. Cell Cycle. 2014;13:3191-201 pubmed 出版商
Sun X, Dang F, Zhang D, Yuan Y, Zhang C, Wu Y, et al. Glucagon-CREB/CRTC2 signaling cascade regulates hepatic BMAL1 protein. J Biol Chem. 2015;290:2189-97 pubmed 出版商
Lee J, Ryu J, Kim E, Jo S, Kim B, Lee H, et al. Adhesive barrier/directional controlled release for cartilage repair by endogenous progenitor cell recruitment. Biomaterials. 2015;39:173-81 pubmed 出版商
Fu X, Rivera A, Tao L, Zhang X. An HSV-2 based oncolytic virus can function as an attractant to guide migration of adoptively transferred T cells to tumor sites. Oncotarget. 2015;6:902-14 pubmed
Zhang Y, Zhao F, Chen L, Wang L, Nephew K, Wu Y, et al. MiR-373 targeting of the Rab22a oncogene suppresses tumor invasion and metastasis in ovarian cancer. Oncotarget. 2014;5:12291-303 pubmed
Karrout Y, Dubuquoy L, Piveteau C, Siepmann F, Moussa E, Wils D, et al. In vivo efficacy of microbiota-sensitive coatings for colon targeting: a promising tool for IBD therapy. J Control Release. 2015;197:121-30 pubmed 出版商
Pérol L, Martin G, Maury S, Cohen J, Piaggio E. Potential limitations of IL-2 administration for the treatment of experimental acute graft-versus-host disease. Immunol Lett. 2014;162:173-84 pubmed 出版商
Liapis V, Labrinidis A, Zinonos I, Hay S, Ponomarev V, Panagopoulos V, et al. Hypoxia-activated pro-drug TH-302 exhibits potent tumor suppressive activity and cooperates with chemotherapy against osteosarcoma. Cancer Lett. 2015;357:160-9 pubmed 出版商
Nagura M, Matsumura N, Baba T, Murakami R, Kharma B, Hamanishi J, et al. Invasion of uterine cervical squamous cell carcinoma cells is facilitated by locoregional interaction with cancer-associated fibroblasts via activating transforming growth factor-beta. Gynecol Oncol. 2015;136:104-11 pubmed 出版商
Wykosky J, Hu J, Gomez G, Taylor T, Villa G, Pizzo D, et al. A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma. Cancer Res. 2015;75:394-404 pubmed 出版商
Porru M, Zappavigna S, Salzano G, Luce A, Stoppacciaro A, Balestrieri M, et al. Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid. Oncotarget. 2014;5:10446-59 pubmed
Luo K, Ko C, Yue G, Gao S, Lee J, Li G, et al. The combined use of Camellia sinensis and metronomic zoledronic acid in a breast cancer-induced osteolysis mouse model. J Cancer Res Clin Oncol. 2015;141:1025-36 pubmed 出版商
Chard L, Maniati E, Wang P, Zhang Z, Gao D, Wang J, et al. A vaccinia virus armed with interleukin-10 is a promising therapeutic agent for treatment of murine pancreatic cancer. Clin Cancer Res. 2015;21:405-16 pubmed 出版商
Zhou S, Chiang C, Xie Y, Li H, Liu K, Kobayashi E, et al. In vivo bioimaging analysis of stromal vascular fraction-assisted fat grafting: the interaction and mutualism of cells and grafted fat. Transplantation. 2014;98:1048-55 pubmed 出版商
Shen S, Berry G, Castellanos Rivera R, Cheung R, Troupes A, Brown S, et al. Functional analysis of the putative integrin recognition motif on adeno-associated virus 9. J Biol Chem. 2015;290:1496-504 pubmed 出版商
Le M, Hamar P, Guo C, Basar E, Perdigão Henriques R, Balaj L, et al. miR-200-containing extracellular vesicles promote breast cancer cell metastasis. J Clin Invest. 2014;124:5109-28 pubmed 出版商
Alexeev V, Lash E, Aguillard A, Corsini L, Bitterman A, Ward K, et al. Radiation protection of the gastrointestinal tract and growth inhibition of prostate cancer xenografts by a single compound. Mol Cancer Ther. 2014;13:2968-77 pubmed 出版商
Thalhammer V, Lopez Garcia L, Herrero Martín D, Hecker R, Laubscher D, Gierisch M, et al. PLK1 phosphorylates PAX3-FOXO1, the inhibition of which triggers regression of alveolar Rhabdomyosarcoma. Cancer Res. 2015;75:98-110 pubmed 出版商
Huuskes B, Wise A, Cox A, Lim E, Payne N, Kelly D, et al. Combination therapy of mesenchymal stem cells and serelaxin effectively attenuates renal fibrosis in obstructive nephropathy. FASEB J. 2015;29:540-53 pubmed 出版商
Greig J, Peng H, Ohlstein J, Medina Jaszek C, Ahonkhai O, Mentzinger A, et al. Intramuscular injection of AAV8 in mice and macaques is associated with substantial hepatic targeting and transgene expression. PLoS ONE. 2014;9:e112268 pubmed 出版商
van Oosterom M, Kreuger R, Buckle T, Mahn W, Bunschoten A, Josephson L, et al. U-SPECT-BioFluo: an integrated radionuclide, bioluminescence, and fluorescence imaging platform. EJNMMI Res. 2014;4:56 pubmed 出版商
Almahariq M, Chao C, Mei F, Hellmich M, Patrikeev I, Motamedi M, et al. Pharmacological inhibition and genetic knockdown of exchange protein directly activated by cAMP 1 reduce pancreatic cancer metastasis in vivo. Mol Pharmacol. 2015;87:142-9 pubmed 出版商
Montagner I, Merlo A, Zuccolotto G, Renier D, Campisi M, Pasut G, et al. Peritoneal tumor carcinomatosis: pharmacological targeting with hyaluronan-based bioconjugates overcomes therapeutic indications of current drugs. PLoS ONE. 2014;9:e112240 pubmed 出版商
Cekic C, Day Y, Sag D, Linden J. Myeloid expression of adenosine A2A receptor suppresses T and NK cell responses in the solid tumor microenvironment. Cancer Res. 2014;74:7250-9 pubmed 出版商
Burkard C, Verheije M, Wicht O, van Kasteren S, van Kuppeveld F, Haagmans B, et al. Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner. PLoS Pathog. 2014;10:e1004502 pubmed 出版商
Adkins C, Nounou M, Mittapalli R, Terrell Hall T, Mohammad A, Jagannathan R, et al. A novel preclinical method to quantitatively evaluate early-stage metastatic events at the murine blood-brain barrier. Cancer Prev Res (Phila). 2015;8:68-76 pubmed 出版商
Stuckey D, Hingtgen S, Karakas N, Rich B, Shah K. Engineering toxin-resistant therapeutic stem cells to treat brain tumors. Stem Cells. 2015;33:589-600 pubmed 出版商
Haug S, Schnerch D, Halbach S, Mastroianni J, Dumit V, Follo M, et al. Metadherin exon 11 skipping variant enhances metastatic spread of ovarian cancer. Int J Cancer. 2015;136:2328-40 pubmed 出版商
Wennerberg E, Kremer V, Childs R, Lundqvist A. CXCL10-induced migration of adoptively transferred human natural killer cells toward solid tumors causes regression of tumor growth in vivo. Cancer Immunol Immunother. 2015;64:225-35 pubmed 出版商
Cekic C, Linden J. Adenosine A2A receptors intrinsically regulate CD8+ T cells in the tumor microenvironment. Cancer Res. 2014;74:7239-49 pubmed 出版商
Bockhorn J, Prat A, Chang Y, Liu X, Huang S, Shang M, et al. Differentiation and loss of malignant character of spontaneous pulmonary metastases in patient-derived breast cancer models. Cancer Res. 2014;74:7406-17 pubmed 出版商
Bersani F, Lee J, Yu M, Morris R, Desai R, Ramaswamy S, et al. Bioengineered implantable scaffolds as a tool to study stromal-derived factors in metastatic cancer models. Cancer Res. 2014;74:7229-38 pubmed 出版商
Ivacik D, Ely A, Ferry N, Arbuthnot P. Sustained inhibition of hepatitis B virus replication in vivo using RNAi-activating lentiviruses. Gene Ther. 2015;22:163-71 pubmed 出版商
Zemp F, McKenzie B, Lun X, Reilly K, McFadden G, Yong V, et al. Cellular factors promoting resistance to effective treatment of glioma with oncolytic myxoma virus. Cancer Res. 2014;74:7260-73 pubmed 出版商
Mateo F, Meca Cortés O, Celià Terrassa T, Fernández Y, Abasolo I, Sánchez Cid L, et al. SPARC mediates metastatic cooperation between CSC and non-CSC prostate cancer cell subpopulations. Mol Cancer. 2014;13:237 pubmed 出版商
Makkouk A, Joshi V, Wongrakpanich A, Lemke C, Gross B, Salem A, et al. Biodegradable microparticles loaded with doxorubicin and CpG ODN for in situ immunization against cancer. AAPS J. 2015;17:184-93 pubmed 出版商
Chapiro J, Sur S, Savic L, Ganapathy Kanniappan S, Reyes J, Duran R, et al. Systemic delivery of microencapsulated 3-bromopyruvate for the therapy of pancreatic cancer. Clin Cancer Res. 2014;20:6406-17 pubmed 出版商
Sandhöfer N, Metzeler K, Rothenberg M, Herold T, Tiedt S, Groiß V, et al. Dual PI3K/mTOR inhibition shows antileukemic activity in MLL-rearranged acute myeloid leukemia. Leukemia. 2015;29:828-38 pubmed 出版商
Gao H, Li K, Tu H, Pan X, Jiang H, Shi B, et al. Development of T cells redirected to glypican-3 for the treatment of hepatocellular carcinoma. Clin Cancer Res. 2014;20:6418-28 pubmed 出版商
Wiegers A, Sticht H, Winkler T, Britt W, Mach M. Identification of a neutralizing epitope within antigenic domain 5 of glycoprotein B of human cytomegalovirus. J Virol. 2015;89:361-72 pubmed 出版商
Wen W, Liang W, Wu J, Kowolik C, Buettner R, Scuto A, et al. Targeting JAK1/STAT3 signaling suppresses tumor progression and metastasis in a peritoneal model of human ovarian cancer. Mol Cancer Ther. 2014;13:3037-48 pubmed 出版商
Edwards C, Best S, Gun S, Claser C, James K, de Oca M, et al. Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infection. Eur J Immunol. 2015;45:130-41 pubmed 出版商
Kaushansky A, Austin L, Mikolajczak S, Lo F, Miller J, Douglass A, et al. Susceptibility to Plasmodium yoelii preerythrocytic infection in BALB/c substrains is determined at the point of hepatocyte invasion. Infect Immun. 2015;83:39-47 pubmed 出版商
Liu L, Mason R, Gimi B. Dynamic bioluminescence and fluorescence imaging of the effects of the antivascular agent Combretastatin-A4P (CA4P) on brain tumor xenografts. Cancer Lett. 2015;356:462-9 pubmed 出版商
Xie X, Tang H, Pengliu -, Kong Y, Wu M, Xiao X, et al. Development of PEA-15 using a potent non-viral vector for therapeutic application in breast cancer. Cancer Lett. 2015;356:374-381 pubmed 出版商
Weiss M, Peñalver Bernabé B, Shin S, Asztalos S, Dubbury S, Mui M, et al. Dynamic transcription factor activity and networks during ErbB2 breast oncogenesis and targeted therapy. Integr Biol (Camb). 2014;6:1170-82 pubmed 出版商
Zhao Y, Scott N, Fynch S, Elkerbout L, Wong W, Mason K, et al. Autoreactive T cells induce necrosis and not BCL-2-regulated or death receptor-mediated apoptosis or RIPK3-dependent necroptosis of transplanted islets in a mouse model of type 1 diabetes. Diabetologia. 2015;58:140-8 pubmed 出版商
Burrell Saward H, Rodgers J, Bradley B, Croft S, Ward T. A sensitive and reproducible in vivo imaging mouse model for evaluation of drugs against late-stage human African trypanosomiasis. J Antimicrob Chemother. 2015;70:510-7 pubmed 出版商
Wegiel B, Larsen R, Gallo D, Chin B, Harris C, Mannam P, et al. Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation. J Clin Invest. 2014;124:4926-40 pubmed 出版商
Schneidawind D, Pierini A, Alvarez M, Pan Y, Baker J, Buechele C, et al. CD4+ invariant natural killer T cells protect from murine GVHD lethality through expansion of donor CD4+CD25+FoxP3+ regulatory T cells. Blood. 2014;124:3320-8 pubmed 出版商
Choi J, Cooper M, Alahmari B, Ritchey J, Collins L, Holt M, et al. Pharmacologic blockade of JAK1/JAK2 reduces GvHD and preserves the graft-versus-leukemia effect. PLoS ONE. 2014;9:e109799 pubmed 出版商
Zuccolotto G, Fracasso G, Merlo A, Montagner I, Rondina M, Bobisse S, et al. PSMA-specific CAR-engineered T cells eradicate disseminated prostate cancer in preclinical models. PLoS ONE. 2014;9:e109427 pubmed 出版商
Rameix Welti M, Le Goffic R, Hervé P, Sourimant J, Remot A, Riffault S, et al. Visualizing the replication of respiratory syncytial virus in cells and in living mice. Nat Commun. 2014;5:5104 pubmed 出版商
Valliyodan B, Van Toai T, Alves J, de Fátima P Goulart P, Lee J, Fritschi F, et al. Expression of root-related transcription factors associated with flooding tolerance of soybean (Glycine max). Int J Mol Sci. 2014;15:17622-43 pubmed 出版商
Llorián Salvador M, Pevida M, Fernández García M, Lastra A, Obaya A, Cal S, et al. Hypernociceptive responses following the intratibial inoculation of RM1 prostate cancer cells in mice. Prostate. 2015;75:70-83 pubmed 出版商
Mansour M, Reed C, Eisenberg A, Tseng J, Twizere J, Daakour S, et al. Targeting oncogenic interleukin-7 receptor signalling with N-acetylcysteine in T cell acute lymphoblastic leukaemia. Br J Haematol. 2015;168:230-8 pubmed 出版商
Han H, Ma J, Zhang K, Li W, Liu C, Zhang Y, et al. Bispecific anti-CD3 x anti-HER2 antibody mediates T cell cytolytic activity to HER2-positive colorectal cancer in vitro and in vivo. Int J Oncol. 2014;45:2446-54 pubmed 出版商
Jokinen E, Laurila N, Koivunen P, Koivunen J. Combining targeted drugs to overcome and prevent resistance of solid cancers with some stem-like cell features. Oncotarget. 2014;5:9295-307 pubmed
Barone A, Sengupta R, Warrington N, Smith E, Wen P, Brekken R, et al. Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma. Oncotarget. 2014;5:9811-22 pubmed
Lepperhof V, Polchynski O, Kruttwig K, Brüggemann C, Neef K, Drey F, et al. Bioluminescent imaging of genetically selected induced pluripotent stem cell-derived cardiomyocytes after transplantation into infarcted heart of syngeneic recipients. PLoS ONE. 2014;9:e107363 pubmed 出版商
Thiele S, Göbel A, Rachner T, Fuessel S, Froehner M, Muders M, et al. WNT5A has anti-prostate cancer effects in vitro and reduces tumor growth in the skeleton in vivo. J Bone Miner Res. 2015;30:471-80 pubmed 出版商
Hartung N, Mollard S, Barbolosi D, Benabdallah A, Chapuisat G, Henry G, et al. Mathematical modeling of tumor growth and metastatic spreading: validation in tumor-bearing mice. Cancer Res. 2014;74:6397-407 pubmed 出版商
Brooks M, Jackson E, Warrington N, Luo J, Forys J, Taylor S, et al. PDE7B is a novel, prognostically significant mediator of glioblastoma growth whose expression is regulated by endothelial cells. PLoS ONE. 2014;9:e107397 pubmed 出版商
Pfeil J, Sepp K, Heiss K, Meister M, Mueller A, Borrmann S. Protection against malaria by immunization with non-attenuated sporozoites under single-dose piperaquine-tetraphosphate chemoprophylaxis. Vaccine. 2014;32:6005-11 pubmed 出版商
Rashid O, Nagahashi M, Ramachandran S, Dumur C, Schaum J, Yamada A, et al. An improved syngeneic orthotopic murine model of human breast cancer progression. Breast Cancer Res Treat. 2014;147:501-12 pubmed 出版商
Hwang D, Jin Y, Lee D, Kim H, Cho H, Chung H, et al. In vivo bioluminescence imaging for prolonged survival of transplanted human neural stem cells using 3D biocompatible scaffold in corticectomized rat model. PLoS ONE. 2014;9:e105129 pubmed 出版商
Patel M, Gleason A, O Malley S, Connolly B, Suresch D, Virostko J, et al. Non-invasive bioluminescence imaging of β-cell function in obese-hyperglycemic [ob/ob] mice. PLoS ONE. 2014;9:e106693 pubmed 出版商
Hentzschel F, Hammerschmidt Kamper C, Börner K, Heiss K, Knapp B, Sattler J, et al. AAV8-mediated in vivo overexpression of miR-155 enhances the protective capacity of genetically attenuated malarial parasites. Mol Ther. 2014;22:2130-41 pubmed 出版商
Planells Ferrer L, Urresti J, Soriano A, Reix S, Murphy D, Ferreres J, et al. MYCN repression of Lifeguard/FAIM2 enhances neuroblastoma aggressiveness. Cell Death Dis. 2014;5:e1401 pubmed 出版商
Sasportas L, Hori S, Pratx G, Gambhir S. Detection and quantitation of circulating tumor cell dynamics by bioluminescence imaging in an orthotopic mammary carcinoma model. PLoS ONE. 2014;9:e105079 pubmed 出版商
Medvetz D, Sun Y, Li C, Khabibullin D, Balan M, Parkhitko A, et al. High-throughput drug screen identifies chelerythrine as a selective inducer of death in a TSC2-null setting. Mol Cancer Res. 2015;13:50-62 pubmed 出版商
Flister M, Endres B, Rudemiller N, Sarkis A, Santarriaga S, Roy I, et al. CXM: a new tool for mapping breast cancer risk in the tumor microenvironment. Cancer Res. 2014;74:6419-29 pubmed 出版商
Tran H, Luitel K, Kim M, Zhang K, Longmore G, Tran D. Transient SNAIL1 expression is necessary for metastatic competence in breast cancer. Cancer Res. 2014;74:6330-40 pubmed 出版商
Horibe T, Torisawa A, Kohno M, Kawakami K. Synergetic cytotoxic activity toward breast cancer cells enhanced by the combination of Antp-TPR hybrid peptide targeting Hsp90 and Hsp70-targeted peptide. BMC Cancer. 2014;14:615 pubmed 出版商
Domanska U, Boer J, Timmer Bosscha H, van Vugt M, Hoving H, Kliphuis N, et al. CXCR4 inhibition enhances radiosensitivity, while inducing cancer cell mobilization in a prostate cancer mouse model. Clin Exp Metastasis. 2014;31:829-39 pubmed 出版商
Yu Z, Geng J, Zhang M, Zhou Y, Fan Q, Chen J. Treatment of osteosarcoma with microwave thermal ablation to induce immunogenic cell death. Oncotarget. 2014;5:6526-39 pubmed
Leten C, Roobrouck V, Struys T, Burns T, Dresselaers T, Vande Velde G, et al. Controlling and monitoring stem cell safety in vivo in an experimental rodent model. Stem Cells. 2014;32:2833-44 pubmed 出版商
Weinberg M, Nicolson S, Bhatt A, McLendon M, Li C, Samulski R. Recombinant adeno-associated virus utilizes cell-specific infectious entry mechanisms. J Virol. 2014;88:12472-84 pubmed 出版商
Barszczyk M, Buczkowicz P, Castelo Branco P, Mack S, Ramaswamy V, Mangerel J, et al. Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells. Acta Neuropathol. 2014;128:863-77 pubmed 出版商
Xie Y, Hicks M, Kaminsky S, Moore M, Crystal R, Rafii A. AAV-mediated persistent bevacizumab therapy suppresses tumor growth of ovarian cancer. Gynecol Oncol. 2014;135:325-32 pubmed 出版商
Luke G, Myers J, Emelianov S, Sokolov K. Sentinel lymph node biopsy revisited: ultrasound-guided photoacoustic detection of micrometastases using molecularly targeted plasmonic nanosensors. Cancer Res. 2014;74:5397-408 pubmed 出版商
Goo H, Rhim H, Kang S. HtrA2/Omi influences the stability of LON protease 1 and prohibitin, proteins involved in mitochondrial homeostasis. Exp Cell Res. 2014;328:456-65 pubmed 出版商
Goffart N, Kroonen J, Di Valentin E, Dedobbeleer M, Denne A, Martinive P, et al. Adult mouse subventricular zones stimulate glioblastoma stem cells specific invasion through CXCL12/CXCR4 signaling. Neuro Oncol. 2015;17:81-94 pubmed 出版商
Taverniti V, Fracassetti D, Del Bò C, Lanti C, Minuzzo M, Klimis Zacas D, et al. Immunomodulatory effect of a wild blueberry anthocyanin-rich extract in human Caco-2 intestinal cells. J Agric Food Chem. 2014;62:8346-51 pubmed 出版商
Speck S, Lim J, Shelake S, Matka M, Stoddard J, Farr A, et al. TGF-? signaling initiated in dendritic cells instructs suppressive effects on Th17 differentiation at the site of neuroinflammation. PLoS ONE. 2014;9:e102390 pubmed 出版商
Husse J, Leliavski A, Tsang A, Oster H, Eichele G. The light-dark cycle controls peripheral rhythmicity in mice with a genetically ablated suprachiasmatic nucleus clock. FASEB J. 2014;28:4950-60 pubmed 出版商
Fay A, Glickman M. An essential nonredundant role for mycobacterial DnaK in native protein folding. PLoS Genet. 2014;10:e1004516 pubmed 出版商
Blanco V, Chu Z, Vallabhapurapu S, Sulaiman M, Kendler A, Rixe O, et al. Phosphatidylserine-selective targeting and anticancer effects of SapC-DOPS nanovesicles on brain tumors. Oncotarget. 2014;5:7105-18 pubmed
Kwon O, Valdez J, Zhang L, Zhang B, Wei X, Su Q, et al. Increased Notch signalling inhibits anoikis and stimulates proliferation of prostate luminal epithelial cells. Nat Commun. 2014;5:4416 pubmed 出版商
Herrmann A, Cherryholmes G, Schroeder A, Phallen J, Alizadeh D, Xin H, et al. TLR9 is critical for glioma stem cell maintenance and targeting. Cancer Res. 2014;74:5218-28 pubmed 出版商
Ho P, Goradia A, Russell M, Chalk A, Milley K, Baker E, et al. Knockdown of PTHR1 in osteosarcoma cells decreases invasion and growth and increases tumor differentiation in vivo. Oncogene. 2015;34:2922-33 pubmed 出版商
Zhou S, Chiang C, Liu K, Li Q. Intravenous transplantation of bone marrow mesenchymal stem cells could effectively promote vascularization and skin regeneration in mechanically stretched skin. Br J Dermatol. 2015;172:1278-85 pubmed 出版商
Jeon M, Ahn C, Kim H, Chung I, Jung S, Kim Y, et al. The intratumoral administration of ferucarbotran conjugated with doxorubicin improved therapeutic effect by magnetic hyperthermia combined with pharmacotherapy in a hepatocellular carcinoma model. J Exp Clin Cancer Res. 2014;33:57 pubmed 出版商
Wyles S, Yamada S, Oommen S, Maleszewski J, Beraldi R, Martinez Fernandez A, et al. Inhibition of DNA topoisomerase II selectively reduces the threat of tumorigenicity following induced pluripotent stem cell-based myocardial therapy. Stem Cells Dev. 2014;23:2274-82 pubmed 出版商
Grześkowiak B, Sanchez Antequera Y, Hammerschmid E, Döblinger M, Eberbeck D, Wozniak A, et al. Nanomagnetic activation as a way to control the efficacy of nucleic acid delivery. Pharm Res. 2015;32:103-21 pubmed 出版商
George S, Vishwamitra D, Manshouri R, Shi P, Amin H. The ALK inhibitor ASP3026 eradicates NPM-ALK? T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model. Oncotarget. 2014;5:5750-63 pubmed
Wang L, Li W, Lin M, Garcia M, Mulholland D, Lilly M, et al. Luteolin, ellagic acid and punicic acid are natural products that inhibit prostate cancer metastasis. Carcinogenesis. 2014;35:2321-30 pubmed 出版商
Wang Y, Li W, Patel S, Cong J, Zhang N, Sabbatino F, et al. Blocking the formation of radiation-induced breast cancer stem cells. Oncotarget. 2014;5:3743-55 pubmed
Higgins K, Park D, Lee G, Curran W, Deng X. Exercise-induced lung cancer regression: mechanistic findings from a mouse model. Cancer. 2014;120:3302-3310 pubmed 出版商
Zaiss A, Zuber J, Chu C, Machado H, Jiao J, Catapang A, et al. Reversible suppression of cyclooxygenase 2 (COX-2) expression in vivo by inducible RNA interference. PLoS ONE. 2014;9:e101263 pubmed 出版商
Martín Saavedra F, Cebrian V, Gómez L, Lopez D, Arruebo M, Wilson C, et al. Temporal and spatial patterning of transgene expression by near-infrared irradiation. Biomaterials. 2014;35:8134-8143 pubmed 出版商
Jacobsen I, Lüttich A, Kurzai O, Hube B, Brock M. In vivo imaging of disseminated murine Candida albicans infection reveals unexpected host sites of fungal persistence during antifungal therapy. J Antimicrob Chemother. 2014;69:2785-96 pubmed 出版商
Reiss L, Fragoulis A, Siegl S, Platen C, Kan Y, Nautiyal J, et al. Interplay between nuclear factor erythroid 2-related factor 2 and amphiregulin during mechanical ventilation. Am J Respir Cell Mol Biol. 2014;51:668-77 pubmed 出版商
Panas M, Letvin N. Role for Gr-1+ cells in the control of high-dose Mycobacterium bovis recombinant BCG. Clin Vaccine Immunol. 2014;21:1120-7 pubmed 出版商
Subramanian M, Rao S, Thacker P, Chatterjee S, Karunagaran D. MiR-29b downregulates canonical Wnt signaling by suppressing coactivators of ?-catenin in human colorectal cancer cells. J Cell Biochem. 2014;115:1974-84 pubmed 出版商
Kulbida R, Wang Y, Mandelkow E, Schoch S, Becker A, Van Loo K. Molecular imaging reveals epileptogenic Ca2+-channel promoter activation in hippocampi of living mice. Brain Struct Funct. 2015;220:3067-73 pubmed 出版商
Francis V, Padmanabhan P, Gummadi S. Snail interacts with hPLSCR1 promoter and down regulates its expression in IMR-32. Biochem Biophys Res Commun. 2014;450:172-7 pubmed 出版商
de Almeida P, Meyer E, Kooreman N, Diecke S, Dey D, Sanchez Freire V, et al. Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance. Nat Commun. 2014;5:3903 pubmed 出版商
Zinonos I, Luo K, Labrinidis A, Liapis V, Hay S, Panagopoulos V, et al. Pharmacologic inhibition of bone resorption prevents cancer-induced osteolysis but enhances soft tissue metastasis in a mouse model of osteolytic breast cancer. Int J Oncol. 2014;45:532-40 pubmed 出版商
. JAK2/STAT3 targeted therapy suppresses tumor invasion via disruption of the EGFRvIII/JAK2/STAT3 axis and associated focal adhesion in EGFRvIII-expressing glioblastoma. Neuro Oncol. 2014;16:1229-43 pubmed 出版商
Alvarez C, Schachter J, de Sá Pinheiro A, Silva L, Verstraeten S, Persechini P, et al. Regulation of extracellular ATP in human erythrocytes infected with Plasmodium falciparum. PLoS ONE. 2014;9:e96216 pubmed 出版商
Zhou J, Riquelme M, Gao X, Ellies L, Sun L, Jiang J. Differential impact of adenosine nucleotides released by osteocytes on breast cancer growth and bone metastasis. Oncogene. 2015;34:1831-42 pubmed 出版商
Scorsone K, Zhang L, Woodfield S, Hicks J, Zage P. The novel kinase inhibitor EMD1214063 is effective against neuroblastoma. Invest New Drugs. 2014;32:815-24 pubmed 出版商
Hsieh T, Chien C, Lee Y, Lin C, Hsieh J, Chao M, et al. Downregulation of SUN2, a novel tumor suppressor, mediates miR-221/222-induced malignancy in central nervous system embryonal tumors. Carcinogenesis. 2014;35:2164-74 pubmed 出版商
Xu X, Ayub B, Liu Z, Serna V, Qiang W, Liu Y, et al. Anti-miR182 reduces ovarian cancer burden, invasion, and metastasis: an in vivo study in orthotopic xenografts of nude mice. Mol Cancer Ther. 2014;13:1729-39 pubmed 出版商
Itakura G, Kobayashi Y, Nishimura S, Iwai H, Takano M, Iwanami A, et al. Control of the Survival and Growth of Human Glioblastoma Grafted Into the Spinal Cord of Mice by Taking Advantage of Immunorejection. Cell Transplant. 2015;24:1299-311 pubmed 出版商
Higgins B, Glenn K, Walz A, Tovar C, Filipovic Z, Hussain S, et al. Preclinical optimization of MDM2 antagonist scheduling for cancer treatment by using a model-based approach. Clin Cancer Res. 2014;20:3742-52 pubmed 出版商
Wang H, Yang L, Wu J, Sun L, Wu J, Tian H, et al. Reduced ischemic injury after stroke in mice by angiogenic gene delivery via ultrasound-targeted microbubble destruction. J Neuropathol Exp Neurol. 2014;73:548-58 pubmed 出版商
Patrick P, Lyons S, Rodrigues T, Brindle K. Oatp1 enhances bioluminescence by acting as a plasma membrane transporter for D-luciferin. Mol Imaging Biol. 2014;16:626-34 pubmed 出版商
Martínez González I, Cruz M, Moreno R, Morell F, Munoz X, Aran J. Human mesenchymal stem cells resolve airway inflammation, hyperreactivity, and histopathology in a mouse model of occupational asthma. Stem Cells Dev. 2014;23:2352-63 pubmed 出版商
Blanchard Z, Mullins N, Ellipeddi P, Lage J, McKinney S, El Etriby R, et al. Geminin overexpression promotes imatinib sensitive breast cancer: a novel treatment approach for aggressive breast cancers, including a subset of triple negative. PLoS ONE. 2014;9:e95663 pubmed 出版商
Kirk K, Hao E, Lahmy R, Itkin Ansari P. Human embryonic stem cell derived islet progenitors mature inside an encapsulation device without evidence of increased biomass or cell escape. Stem Cell Res. 2014;12:807-14 pubmed 出版商
Suo G, Sadarangani A, Tang W, Cowan B, Wang J. Telomerase expression abrogates rapamycin-induced irreversible growth arrest of uterine fibroid smooth muscle cells. Reprod Sci. 2014;21:1161-70 pubmed 出版商
Nölting S, Giubellino A, Tayem Y, Young K, Lauseker M, Bullova P, et al. Combination of 13-Cis retinoic acid and lovastatin: marked antitumor potential in vivo in a pheochromocytoma allograft model in female athymic nude mice. Endocrinology. 2014;155:2377-90 pubmed 出版商
Alzuguren P, Hervas Stubbs S, Gonzalez Aseguinolaza G, Poutou J, Fortes P, Mancheno U, et al. Transient depletion of specific immune cell populations to improve adenovirus-mediated transgene expression in the liver. Liver Int. 2015;35:1274-89 pubmed 出版商
da Silva Souza H, Lira M, Costa Junior H, da Cruz C, Vasconcellos J, Mendes A, et al. Inhibitors of the 5-lipoxygenase arachidonic acid pathway induce ATP release and ATP-dependent organic cation transport in macrophages. Biochim Biophys Acta. 2014;1838:1967-77 pubmed 出版商
Yu W, Grubor Bauk B, Gargett T, Garrod T, Gowans E. A novel challenge model to evaluate the efficacy of hepatitis C virus vaccines in mice. Vaccine. 2014;32:3409-16 pubmed 出版商
Rossnagl S, von Au A, Vasel M, Cecchini M, Cecchini A, Nakchbandi I. Blood clot formation does not affect metastasis formation or tumor growth in a murine model of breast cancer. PLoS ONE. 2014;9:e94922 pubmed 出版商
Kizima L, Rodriguez A, Kenney J, Derby N, Mizenina O, Menon R, et al. A potent combination microbicide that targets SHIV-RT, HSV-2 and HPV. PLoS ONE. 2014;9:e94547 pubmed 出版商
Liu W, Li Y, Feng S, Ning J, Wang J, Gou M, et al. Magnetically controllable 3D microtissues based on magnetic microcryogels. Lab Chip. 2014;14:2614-25 pubmed 出版商
Meraz I, Hearnden C, Liu X, Yang M, Williams L, Savage D, et al. Multivalent presentation of MPL by porous silicon microparticles favors T helper 1 polarization enhancing the anti-tumor efficacy of doxorubicin nanoliposomes. PLoS ONE. 2014;9:e94703 pubmed 出版商
Miao H, Choi B, Suryadevara C, Sanchez Perez L, Yang S, De Leon G, et al. EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma. PLoS ONE. 2014;9:e94281 pubmed 出版商
Mann J, McKay P, Fiserova A, Klein K, Cope A, Rogers P, et al. Enhanced immunogenicity of an HIV-1 DNA vaccine delivered with electroporation via combined intramuscular and intradermal routes. J Virol. 2014;88:6959-69 pubmed 出版商
Wang Z, Wang B, Shi Y, Xu C, Xiao H, Ma L, et al. Oncogenic miR-20a and miR-106a enhance the invasiveness of human glioma stem cells by directly targeting TIMP-2. Oncogene. 2015;34:1407-19 pubmed 出版商
Chen E, Markosyan N, Connolly E, Lawson J, Li X, Grant G, et al. Myeloid Cell COX-2 deletion reduces mammary tumor growth through enhanced cytotoxic T-lymphocyte function. Carcinogenesis. 2014;35:1788-97 pubmed 出版商
Kozyreva V, McLaughlin S, Livengood R, Calkins R, Kelley L, Rajulapati A, et al. NEDD9 regulates actin dynamics through cortactin deacetylation in an AURKA/HDAC6-dependent manner. Mol Cancer Res. 2014;12:681-93 pubmed 出版商
Ung N, Putoczki T, Stylli S, Ng I, Mariadason J, Chan T, et al. Anti-EGFR therapeutic efficacy correlates directly with inhibition of STAT3 activity. Cancer Biol Ther. 2014;15:623-32 pubmed 出版商
Verbeek F, van der Vorst J, Tummers Q, Boonstra M, De Rooij K, Lowik C, et al. Near-infrared fluorescence imaging of both colorectal cancer and ureters using a low-dose integrin targeted probe. Ann Surg Oncol. 2014;21 Suppl 4:S528-37 pubmed 出版商
Pizzitola I, Anjos Afonso F, Rouault Pierre K, Lassailly F, Tettamanti S, Spinelli O, et al. Chimeric antigen receptors against CD33/CD123 antigens efficiently target primary acute myeloid leukemia cells in vivo. Leukemia. 2014;28:1596-605 pubmed 出版商
Wilson C, Martín Saavedra F, Padilla F, Fabiilli M, Zhang M, Baez A, et al. Patterning expression of regenerative growth factors using high intensity focused ultrasound. Tissue Eng Part C Methods. 2014;20:769-79 pubmed 出版商
Bakhsheshian J, Wei B, Chang K, Shukla S, Ambudkar S, Simpson R, et al. Bioluminescent imaging of drug efflux at the blood-brain barrier mediated by the transporter ABCG2. Proc Natl Acad Sci U S A. 2013;110:20801-6 pubmed 出版商
Demajo S, Uribesalgo I, Gutierrez A, Ballare C, Capdevila S, Roth M, et al. ZRF1 controls the retinoic acid pathway and regulates leukemogenic potential in acute myeloid leukemia. Oncogene. 2014;33:5501-10 pubmed 出版商
Zhu S, Denman C, Cobanoglu Z, Kiany S, Lau C, Gottschalk S, et al. The narrow-spectrum HDAC inhibitor entinostat enhances NKG2D expression without NK cell toxicity, leading to enhanced recognition of cancer cells. Pharm Res. 2015;32:779-92 pubmed 出版商
Yi B, Hwang K, Aboody K, Jeung E, Kim S, Choi K. Selective antitumor effect of neural stem cells expressing cytosine deaminase and interferon-beta against ductal breast cancer cells in cellular and xenograft models. Stem Cell Res. 2014;12:36-48 pubmed 出版商
Iwai H, Nori S, Nishimura S, Yasuda A, Takano M, Tsuji O, et al. Transplantation of neural stem/progenitor cells at different locations in mice with spinal cord injury. Cell Transplant. 2014;23:1451-64 pubmed 出版商
Lavergne M, Jourdan M, Blechet C, Guyetant S, Pape A, Heuzé Vourc h N, et al. Beneficial role of overexpression of TFPI-2 on tumour progression in human small cell lung cancer. FEBS Open Bio. 2013;3:291-301 pubmed 出版商
Chen S, Johnston J, Sandhu A, Bish L, Hovhannisyan R, Jno Charles O, et al. Enhancing the utility of adeno-associated virus gene transfer through inducible tissue-specific expression. Hum Gene Ther Methods. 2013;24:270-8 pubmed 出版商
Pinto da Silva L, Esteves da Silva J. Firefly luciferin as a multifunctional chemiluminescence molecule. Photochem Photobiol Sci. 2013;12:1615-21 pubmed 出版商
Viviani V, Prado R, Neves D, Kato D, Barbosa J. A route from darkness to light: emergence and evolution of luciferase activity in AMP-CoA-ligases inferred from a mealworm luciferase-like enzyme. Biochemistry. 2013;52:3963-73 pubmed 出版商
Liang Y, Agren L, Lyczek A, Walczak P, Bulte J. Neural progenitor cell survival in mouse brain can be improved by co-transplantation of helper cells expressing bFGF under doxycycline control. Exp Neurol. 2013;247:73-9 pubmed 出版商
Martín Saavedra F, Wilson C, Voellmy R, Vilaboa N, Franceschi R. Spatiotemporal control of vascular endothelial growth factor expression using a heat-shock-activated, rapamycin-dependent gene switch. Hum Gene Ther Methods. 2013;24:160-70 pubmed 出版商
Paciello L, Falco F, Landi C, Parascandola P. Strengths and weaknesses in the determination of Saccharomyces cerevisiae cell viability by ATP-based bioluminescence assay. Enzyme Microb Technol. 2013;52:157-62 pubmed 出版商
Eichhorn T, Hiller C, Hirschfelder K, Frank M, Krauth Siegel R, Muller R, et al. Identification by high-throughput in silico screening of radio-protecting compounds targeting the DNA-binding domain of the tumor suppressor p53. Cancer Genomics Proteomics. 2013;10:35-45 pubmed
El Jamal N, Dubuquoy L, Auwerx J, Bertin B, Desreumaux P. In vivo imaging reveals selective PPAR activity in the skin of peroxisome proliferator-activated receptor responsive element-luciferase reporter mice. Exp Dermatol. 2013;22:137-40 pubmed 出版商
Viviani V, Carmargo I, Amaral D. A transcriptional survey of the cDNA library of Macrolampis sp2 firefly lanterns (Coleoptera: Lampyridae). Comp Biochem Physiol Part D Genomics Proteomics. 2013;8:82-5 pubmed 出版商
El Haj A, Glossop J, Sura H, Lees M, Hu B, Wolbank S, et al. An in vitro model of mesenchymal stem cell targeting using magnetic particle labelling. J Tissue Eng Regen Med. 2015;9:724-33 pubmed 出版商
Pinto da Silva L, Santos A, Esteves da Silva J. Efficient firefly chemi/bioluminescence: evidence for chemiexcitation resulting from the decomposition of a neutral firefly dioxetanone molecule. J Phys Chem A. 2013;117:94-100 pubmed 出版商
Kojima R, Takakura H, Ozawa T, Tada Y, Nagano T, Urano Y. Rational design and development of near-infrared-emitting firefly luciferins available in vivo. Angew Chem Int Ed Engl. 2013;52:1175-9 pubmed 出版商
Woodroofe C, Meisenheimer P, Klaubert D, Kovic Y, Rosenberg J, Behney C, et al. Novel heterocyclic analogues of firefly luciferin. Biochemistry. 2012;51:9807-13 pubmed 出版商
Li J, Chen L, Du L, Li M. Cage the firefly luciferin! - a strategy for developing bioluminescent probes. Chem Soc Rev. 2013;42:662-76 pubmed 出版商
Terada N, Saitoh Y, Saitoh S, Ohno N, Fujishita K, Koizumi S, et al. Visualization of ATP with luciferin-luciferase reaction in mouse skeletal muscles using an "in vivo cryotechnique". Microsc Microanal. 2012;18:1030-6 pubmed 出版商
Presiado I, Erez Y, Simkovitch R, Shomer S, Gepshtein R, Pinto da Silva L, et al. Excited-state proton transfer of firefly dehydroluciferin. J Phys Chem A. 2012;116:10770-9 pubmed 出版商
Vieira J, Pinto da Silva L, Esteves da Silva J. Advances in the knowledge of light emission by firefly luciferin and oxyluciferin. J Photochem Photobiol B. 2012;117:33-9 pubmed 出版商
Hirano T, Nagai H, Matsuhashi T, Hasumi Y, Iwano S, Ito K, et al. Spectroscopic studies of the color modulation mechanism of firefly (beetle) bioluminescence with amino-analogs of luciferin and oxyluciferin. Photochem Photobiol Sci. 2012;11:1281-4 pubmed 出版商
Zaitseva M, Kapnick S, Golding H. Measurements of vaccinia virus dissemination using whole body imaging: approaches for predicting of lethality in challenge models and testing of vaccines and antiviral treatments. Methods Mol Biol. 2012;890:161-76 pubmed 出版商
Takakura H, Kojima R, Ozawa T, Nagano T, Urano Y. Development of 5'- and 7'-substituted luciferin analogues as acid-tolerant substrates of firefly luciferase. Chembiochem. 2012;13:1424-7 pubmed 出版商
Li A, Uzgare A, Laforge Y. Definition of metabolism-dependent xenobiotic toxicity with co-cultures of human hepatocytes and mouse 3T3 fibroblasts in the novel integrated discrete multiple organ co-culture (IdMOC) experimental system: results with model toxicants aflatoxin B1, . Chem Biol Interact. 2012;199:1-8 pubmed 出版商
Alsaadi M, Italia J, Mullen A, Ravi Kumar M, Candlish A, Williams R, et al. The efficacy of aerosol treatment with non-ionic surfactant vesicles containing amphotericin B in rodent models of leishmaniasis and pulmonary aspergillosis infection. J Control Release. 2012;160:685-91 pubmed 出版商
Bryan N, Ahswin H, Smart N, Bayon Y, Hunt J. In vitro activation of human leukocytes in response to contact with synthetic hernia meshes. Clin Biochem. 2012;45:672-6 pubmed 出版商
Roncoroni C, Rizzi N, Brunialti E, Cali J, Klaubert D, Maggi A, et al. Molecular imaging of cytochrome P450 activity in mice. Pharmacol Res. 2012;65:531-6 pubmed 出版商
Hiyama M, Akiyama H, Yamada K, Koga N. Theoretical study of absorption and fluorescence spectra of firefly luciferin in aqueous solutions. Photochem Photobiol. 2012;88:889-98 pubmed 出版商
Conley N, Dragulescu Andrasi A, Rao J, Moerner W. A selenium analogue of firefly D-luciferin with red-shifted bioluminescence emission. Angew Chem Int Ed Engl. 2012;51:3350-3 pubmed 出版商
Cordeau P, Kriz J. Real-time imaging after cerebral ischemia: model systems for visualization of inflammation and neuronal repair. Methods Enzymol. 2012;506:117-33 pubmed 出版商
Shanmugasundararaj S, Lehle S, Yamodo H, Husain S, Tseng C, Nguyen K, et al. The location and nature of general anesthetic binding sites on the active conformation of firefly luciferase; a time resolved photolabeling study. PLoS ONE. 2012;7:e29854 pubmed 出版商
Mäger I, Langel K, Lehto T, Eiríksdóttir E, Langel U. The role of endocytosis on the uptake kinetics of luciferin-conjugated cell-penetrating peptides. Biochim Biophys Acta. 2012;1818:502-11 pubmed 出版商
Navizet I, Liu Y, Ferré N, Roca Sanjuán D, Lindh R. The chemistry of bioluminescence: an analysis of chemical functionalities. Chemphyschem. 2011;12:3064-76 pubmed 出版商
Meisenheimer P, Uyeda H, Ma D, Sobol M, McDougall M, Corona C, et al. Proluciferin acetals as bioluminogenic substrates for cytochrome P450 activity and probes for CYP3A inhibition. Drug Metab Dispos. 2011;39:2403-10 pubmed 出版商
Fields R. Imaging single photons and intrinsic optical signals for studies of vesicular and non-vesicular ATP release from axons. Front Neuroanat. 2011;5:32 pubmed 出版商
Bianconcini A, Lupo A, Capone S, Quadro L, Monti M, Zurlo D, et al. Transcriptional activity of the murine retinol-binding protein gene is regulated by a multiprotein complex containing HMGA1, p54 nrb/NonO, protein-associated splicing factor (PSF) and steroidogenic factor 1 (SF1)/liver receptor homologue 1 (LRH-1). Int J Biochem Cell Biol. 2009;41:2189-203 pubmed 出版商
Lam B, Joyce G. Autocatalytic aptazymes enable ligand-dependent exponential amplification of RNA. Nat Biotechnol. 2009;27:288-92 pubmed 出版商
产品信息
目录代码 :
L9504
产品名称 :
D-荧光素
产品类型 :
PROTEINS & ENZYMES
Product Group :
蛋白&通路技术
产品描述 :
synthetic
公司信息
西格玛奥德里奇
上海市徐汇区淮海中路1010号嘉华中心41楼
techservCN@sial.com
http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
公司总部: 美国
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