产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
产品类型 :
抗体
产品名称 :
单克隆抗微管相关蛋白2(2a+2b)在小鼠生产的抗体
目录 :
M1406
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AP-20
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 212
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:500; 图 s2a
Wu Y, Shao W, Todd T, Tong J, Yue M, Koga S, et al. Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD. Cell Rep. 2021;36:109581 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 s1a
Modafferi S, Zhong X, Kleensang A, Murata Y, Fagiani F, Pamies D, et al. Gene-Environment Interactions in Developmental Neurotoxicity: a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres. Environ Health Perspect. 2021;129:77001 pubmed 出版商
  • 免疫组化; 人类; 1:1000; 图 5c
Seol B, Kim Y, Cho Y. Modeling Sialidosis with Neural Precursor Cells Derived from Patient-Derived Induced Pluripotent Stem Cells. Int J Mol Sci. 2021;22: pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 6g
Sase S, Almad A, Boecker C, Guedes Dias P, Li J, Takanohashi A, et al. TUBB4A mutations result in both glial and neuronal degeneration in an H-ABC leukodystrophy mouse model. elife. 2020;9: pubmed 出版商
  • 免疫细胞化学; 人类; 图 3b
Cifelli J, Berg K, Yang J. Benzothiazole amphiphiles promote RasGRF1-associated dendritic spine formation in human stem cell-derived neurons. FEBS Open Bio. 2020;10:386-395 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 1b
  • 免疫组化-冰冻切片; 大鼠; 图 1f
Rojek K, Krzemien J, Dolezyczek H, Boguszewski P, Kaczmarek L, Konopka W, et al. Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice. PLoS Biol. 2019;17:e3000253 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 4d
Wang S, Ko S, Kim Y, Jo S, Lee S, Jung S, et al. Capsaicin upregulates HDAC2 via TRPV1 and impairs neuronal maturation in mice. Exp Mol Med. 2018;50:e455 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 4e
  • 免疫细胞化学; 小鼠; 1:100; 图 s2d
  • 免疫印迹; 小鼠; 图 s2f
Bobo Jiménez V, Delgado Esteban M, Angibaud J, Sánchez Morán I, de la Fuente A, Yajeya J, et al. APC/CCdh1-Rock2 pathway controls dendritic integrity and memory. Proc Natl Acad Sci U S A. 2017;114:4513-4518 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 5e
Moradi M, Sivadasan R, Saal L, Lüningschrör P, Dombert B, Rathod R, et al. Differential roles of α-, β-, and γ-actin in axon growth and collateral branch formation in motoneurons. J Cell Biol. 2017;216:793-814 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 5c
Menges S, Minakaki G, Schaefer P, Meixner H, Prots I, Schlötzer Schrehardt U, et al. Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress. Sci Rep. 2017;7:42942 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 图 3d
Sartore R, Cardoso S, Lages Y, Paraguassu J, Stelling M, Madeiro da Costa R, et al. Trace elements during primordial plexiform network formation in human cerebral organoids. Peerj. 2017;5:e2927 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 st4
Qi Y, Zhang X, Renier N, Wu Z, Atkin T, Sun Z, et al. Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells. Nat Biotechnol. 2017;35:154-163 pubmed 出版商
  • 免疫组化; 人类; 1:3000; 图 2c
Ronellenfitsch M, Oh J, Satomi K, Sumi K, Harter P, Steinbach J, et al. CASP9 germline mutation in a family with multiple brain tumors. Brain Pathol. 2018;28:94-102 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 表 2
Kilic O, Pamies D, Lavell E, Schiapparelli P, Feng Y, Hartung T, et al. Brain-on-a-chip model enables analysis of human neuronal differentiation and chemotaxis. Lab Chip. 2016;16:4152-4162 pubmed
  • 免疫细胞化学; 大鼠; 1:500
Bisbal M, Quassollo G, Caceres A. Imaging Golgi Outposts in Fixed and Living Neurons. Methods Mol Biol. 2016;1496:31-9 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 表 s4
Hansen S, Stummann T, Borland H, Hasholt L, Tumer Z, Nielsen J, et al. Induced pluripotent stem cell - derived neurons for the study of spinocerebellar ataxia type 3. Stem Cell Res. 2016;17:306-317 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:2000; 图 3
Alves S, Marais T, Biferi M, Furling D, Marinello M, El Hachimi K, et al. Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins. Mol Neurodegener. 2016;11:58 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 s5c
  • 免疫印迹; 小鼠; 1:1000; 图 7b
Itoh Y, Higuchi M, Oishi K, Kishi Y, Okazaki T, Sakai H, et al. PDK1-Akt pathway regulates radial neuronal migration and microtubules in the developing mouse neocortex. Proc Natl Acad Sci U S A. 2016;113:E2955-64 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1b
Garcia C, Videla Richardson G, Dimopoulos N, Fernandez Espinosa D, Miriuka S, Sevlever G, et al. Human Pluripotent Stem Cells and Derived Neuroprogenitors Display Differential Degrees of Susceptibility to BH3 Mimetics ABT-263, WEHI-539 and ABT-199. PLoS ONE. 2016;11:e0152607 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 8e
Zhang Y, Gendron T, Grima J, Sasaguri H, Jansen West K, Xu Y, et al. C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins. Nat Neurosci. 2016;19:668-677 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:400; 图 5
Cui Y, Han J, Xiao Z, Chen T, Wang B, Chen B, et al. The miR-20-Rest-Wnt signaling axis regulates neural progenitor cell differentiation. Sci Rep. 2016;6:23300 pubmed 出版商
  • 免疫组化; 大鼠; 1:500
Collazos Castro J, García Rama C, Alves Sampaio A. Glial progenitor cell migration promotes CNS axon growth on functionalized electroconducting microfibers. Acta Biomater. 2016;35:42-56 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 3
Kishi N, MacDonald J, Ye J, Molyneaux B, Azim E, Macklis J. Reduction of aberrant NF-κB signalling ameliorates Rett syndrome phenotypes in Mecp2-null mice. Nat Commun. 2016;7:10520 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:500; 图 4
Müller A, Stellmacher A, Freitag C, Landgraf P, Dieterich D. Monitoring Astrocytic Proteome Dynamics by Cell Type-Specific Protein Labeling. PLoS ONE. 2015;10:e0145451 pubmed 出版商
  • 免疫组化; 人类; 图 2a
Ho S, Hartley B, TCW J, Beaumont M, Stafford K, Slesinger P, et al. Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells. Methods. 2016;101:113-24 pubmed 出版商
  • 免疫组化; 人类; 1:1000; 图 4b
Uchida H, Morita T, Niizuma K, Kushida Y, Kuroda Y, Wakao S, et al. Transplantation of Unique Subpopulation of Fibroblasts, Muse Cells, Ameliorates Experimental Stroke Possibly via Robust Neuronal Differentiation. Stem Cells. 2016;34:160-73 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:200
Mohammadi A, Attari F, Babapour V, Hassani S, Masoudi N, Shahverdi A, et al. Generation of Rat Embryonic Germ Cells via Inhibition of TGFß and MEK Pathways. Cell J. 2015;17:288-95 pubmed
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 S2d
Deleyrolle L, Sabourin J, Rothhut B, Fujita H, Guichet P, Teigell M, et al. OCAM regulates embryonic spinal cord stem cell proliferation by modulating ErbB2 receptor. PLoS ONE. 2015;10:e0122337 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500
Videla Richardson G, Garcia C, Roisman A, Slavutsky I, Fernandez Espinosa D, Romorini L, et al. Specific Preferences in Lineage Choice and Phenotypic Plasticity of Glioma Stem Cells Under BMP4 and Noggin Influence. Brain Pathol. 2016;26:43-61 pubmed 出版商
  • 免疫细胞化学; 小鼠
Riecken L, Tawamie H, Dornblut C, Buchert R, Ismayel A, Schulz A, et al. Inhibition of RAS activation due to a homozygous ezrin variant in patients with profound intellectual disability. Hum Mutat. 2015;36:270-8 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:250
Vergaño Vera E, Diaz Guerra E, Rodríguez Traver E, Méndez Gómez H, Solis O, Pignatelli J, et al. Nurr1 blocks the mitogenic effect of FGF-2 and EGF, inducing olfactory bulb neural stem cells to adopt dopaminergic and dopaminergic-GABAergic neuronal phenotypes. Dev Neurobiol. 2015;75:823-41 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:50
Rousseau E, Michel P, Hirsch E. The iron-binding protein lactoferrin protects vulnerable dopamine neurons from degeneration by preserving mitochondrial calcium homeostasis. Mol Pharmacol. 2013;84:888-98 pubmed 出版商
Bugallo R, Marlin E, Baltanás A, Toledo E, Ferrero R, Vinueza Gavilanes R, et al. Fine tuning of the unfolded protein response by ISRIB improves neuronal survival in a model of amyotrophic lateral sclerosis. Cell Death Dis. 2020;11:397 pubmed 出版商
Dong S, Aguirre Hernández C, Scrivo A, Eliscovich C, Arias E, Bravo Cordero J, et al. Monitoring spatiotemporal changes in chaperone-mediated autophagy in vivo. Nat Commun. 2020;11:645 pubmed 出版商
Laperle A, Sances S, Yucer N, Dardov V, García V, Ho R, et al. iPSC modeling of young-onset Parkinson's disease reveals a molecular signature of disease and novel therapeutic candidates. Nat Med. 2020;26:289-299 pubmed 出版商
Giralt A, Brito V, Pardo M, Rubio S, Marion Poll L, Martín Ibáñez R, et al. Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation. Exp Neurol. 2020;323:113095 pubmed 出版商
Saito K, Okamoto M, Watanabe Y, Noguchi N, Nagasaka A, Nishina Y, et al. Dorsal-to-Ventral Cortical Expansion Is Physically Primed by Ventral Streaming of Early Embryonic Preplate Neurons. Cell Rep. 2019;29:1555-1567.e5 pubmed 出版商
Aron Badin R, Bugi A, Williams S, Vadori M, Michael M, Jan C, et al. MHC matching fails to prevent long-term rejection of iPSC-derived neurons in non-human primates. Nat Commun. 2019;10:4357 pubmed 出版商
Ryu B, Sekine H, Kawamata T, Shimizu T. Sticker method for preparation of frozen section using adhesive film. J Neurosci Methods. 2019;328:108436 pubmed 出版商
Bogetofte H, Jensen P, Okarmus J, Schmidt S, Agger M, Ryding M, et al. Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation. Neurobiol Dis. 2019;132:104581 pubmed 出版商
Kinoshita H, Maki T, Yasuda K, Kishida N, Sasaoka N, Takagi Y, et al. KUS121, a valosin-containing protein modulator, attenuates ischemic stroke via preventing ATP depletion. Sci Rep. 2019;9:11519 pubmed 出版商
Mathkar P, Suresh D, Dunn J, Tom C, Mattis V. Characterization of Neurodevelopmental Abnormalities in iPSC-Derived Striatal Cultures from Patients with Huntington's Disease. J Huntingtons Dis. 2019;8:257-269 pubmed 出版商
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Huang Y, Zhou B, Nabet A, Wernig M, Sudhof T. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk. J Neurosci. 2019;39:7408-7427 pubmed 出版商
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Vatine G, Barrile R, Workman M, Sances S, Barriga B, Rahnama M, et al. Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications. Cell Stem Cell. 2019;24:995-1005.e6 pubmed 出版商
Chanda S, Ang C, Lee Q, Ghebrial M, Haag D, Shibuya Y, et al. Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity. Cell Stem Cell. 2019;: pubmed 出版商
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Mao H, Hamodeh S, Skodras A, Sultan F. Quantitative organization of the excitatory synapses of the primate cerebellar nuclei: further evidence for a specialized architecture underlying the primate cerebellum. Brain Struct Funct. 2019;224:1987-1998 pubmed 出版商
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Monderer Rothkoff G, Tal N, Risman M, Shani O, Nissim Rafinia M, Malki Feldman L, et al. AUTS2 isoforms control neuronal differentiation. Mol Psychiatry. 2019;: pubmed 出版商
Goto Silva L, Ayad N, Herzog I, Silva N, Lamien B, Orlande H, et al. Computational fluid dynamic analysis of physical forces playing a role in brain organoid cultures in two different multiplex platforms. BMC Dev Biol. 2019;19:3 pubmed 出版商
Domise M, Sauvé F, Didier S, Caillerez R, Bégard S, Carrier S, et al. Neuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediated process. Cell Death Dis. 2019;10:221 pubmed 出版商
Ueno M, Sugimoto M, Ohtsubo K, Sakai N, Endo A, Shikano K, et al. The effect of electroconvulsive seizure on survival, neuronal differentiation, and expression of the maturation marker in the adult mouse hippocampus. J Neurochem. 2019;149:488-498 pubmed 出版商
Sando R, Jiang X, Sudhof T. Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins. Science. 2019;363: pubmed 出版商
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Moghadam F, Mesbah Ardakani M, Nasr Esfahani M. Ferulic Acid exerts concentration-dependent anti-apoptotic and neuronal differentiation-inducing effects in PC12 and mouse neural stem cells. Eur J Pharmacol. 2018;841:104-112 pubmed 出版商
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Li C, Götz J. Pyk2 is a Novel Tau Tyrosine Kinase that is Regulated by the Tyrosine Kinase Fyn. J Alzheimers Dis. 2018;64:205-221 pubmed 出版商
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Mondal T, Juvvuna P, Kirkeby A, Mitra S, Kosalai S, Traxler L, et al. Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis. Cancer Cell. 2018;33:417-434.e7 pubmed 出版商
Ganzer P, Beringer C, Shumsky J, Nwaobasi C, Moxon K. Serotonin receptor and dendritic plasticity in the spinal cord mediated by chronic serotonergic pharmacotherapy combined with exercise following complete SCI in the adult rat. Exp Neurol. 2018;304:132-142 pubmed 出版商
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Fukui H, Rünker A, Fabel K, Buchholz F, Kempermann G. Transcription factor Runx1 is pro-neurogenic in adult hippocampal precursor cells. PLoS ONE. 2018;13:e0190789 pubmed 出版商
Mikheev A, Mikheeva S, Tokita M, Severs L, Rostomily R. Twist1 mediated regulation of glioma tumorigenicity is dependent on mode of mouse neural progenitor transformation. Oncotarget. 2017;8:107716-107729 pubmed 出版商
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Minakaki G, Menges S, Kittel A, Emmanouilidou E, Schaeffner I, Barkovits K, et al. Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype. Autophagy. 2017;:1-61 pubmed 出版商
Wang B, Iyengar R, Li Harms X, Joo J, Wright C, Lavado A, et al. The Autophagy-Inducing Kinases, ULK1 and ULK2, Regulate Axon Guidance in the Developing Mouse Forebrain via a Noncanonical Pathway. Autophagy. 2017;: pubmed 出版商
Cisbani G, Maxan A, Kordower J, Planel E, Freeman T, Cicchetti F. Presence of tau pathology within foetal neural allografts in patients with Huntington's and Parkinson's disease. Brain. 2017;140:2982-2992 pubmed 出版商
von Brzezinski L, Säring P, Landgraf P, Cammann C, Seifert U, Dieterich D. Low Neurotoxicity of ONX-0914 Supports the Idea of Specific Immunoproteasome Inhibition as a Side-Effect-Limiting, Therapeutic Strategy. Eur J Microbiol Immunol (Bp). 2017;7:234-245 pubmed 出版商
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产品信息
Product No. :
M1406
产品名称 :
单克隆抗微管相关蛋白2(2a+2b)在小鼠生产的抗体
宿主 :
小鼠
共轭标签 :
未共轭
抗体类型 :
单克隆
Clone Number (if monoclonal) :
AP-20
应用/描述 :
Suitable for immunocytochemistry; western blot: 1:500 using rat brain enriched microtubule protein preparation or rat cerebral cortex extract
物种活性 :
Xenopus, bovine, human, mouse, rat, aquatic salamander, quail
抗体亚型 :
IgG1
储存 :
存放在-20°C
更多信息或购买 :
公司信息
西格玛奥德里奇
上海市徐汇区淮海中路1010号嘉华中心41楼
techservCN@sial.com
http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
公司总部: 美国
Sigma-Aldrich是一家在生命科学领域领先的且拥有高科技产品的公司,致力于为生命科学、制药化工等领域提供高质量的服务和产品。