产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
FLUKA, Sigma-Aldrich, Roche Applied Science
产品类型 :
抗体
产品名称 :
单克隆抗鼠双微基因2在小鼠生产的抗体
目录 :
M4308
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
SMP14
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫沉淀
更多信息或购买 :
文章摘录数: 23
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 1c
Liu T, Xiong J, Yi S, Zhang H, Zhou S, Gu L, et al. FKBP12 enhances sensitivity to chemotherapy-induced cancer cell apoptosis by inhibiting MDM2. Oncogene. 2017;36:1678-1686 pubmed 出版商
Zhou Y, Wang L, Ban X, Zeng T, Zhu Y, Li M, et al. DHRS2 inhibits cell growth and motility in esophageal squamous cell carcinoma. Oncogene. 2017;: pubmed 出版商
Chang T, Wang S, Chen L, Shih Y, Chang L, Liu S, et al. Regulation of the Abundance of Kaposi's Sarcoma-Associated Herpesvirus ORF50 Protein by Oncoprotein MDM2. PLoS Pathog. 2016;12:e1005918 pubmed 出版商
Moussa R, Kovacevic Z, Richardson D. Differential targeting of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by chelators with anti-proliferative activity in a range of tumor cell-types. Oncotarget. 2015;6:29694-711 pubmed 出版商
Lezina L, Aksenova V, Fedorova O, Malikova D, Shuvalov O, Antonov A, et al. KMT Set7/9 affects genotoxic stress response via the Mdm2 axis. Oncotarget. 2015;6:25843-55 pubmed 出版商
Payne L, Eves R, Jia L, Mak A. p53 Down regulates PDGF-induced formation of circular dorsal ruffles in rat aortic smooth muscle cells. PLoS ONE. 2014;9:e108257 pubmed 出版商
Oliveira Alves M, da Mota Delgado A, Balducci I, Carvalho Y, Cavalcante A, Almeida J. Study of MDM2 and SUMO-1 expression in actinic cheilitis and lip cancer. Arch Dermatol Res. 2014;306:837-41 pubmed 出版商
Hamilton G, Abraham A, Morton J, Sampson O, Pefani D, Khoronenkova S, et al. AKT regulates NPM dependent ARF localization and p53mut stability in tumors. Oncotarget. 2014;5:6142-67 pubmed
Kasim V, Huang C, Zhang J, Jia H, Wang Y, Yang L, et al. Synergistic cooperation of MDM2 and E2F1 contributes to TAp73 transcriptional activity. Biochem Biophys Res Commun. 2014;449:319-26 pubmed 出版商
Iqbal N, Xu L, Devitt C, Skapek S. Isolation and characterization of mammalian cells expressing the Arf promoter during eye development. Biotechniques. 2014;56:239-49 pubmed 出版商
Bista M, Petrovich M, Fersht A. MDMX contains an autoinhibitory sequence element. Proc Natl Acad Sci U S A. 2013;110:17814-9 pubmed 出版商
Gonon G, Groetz J, De Toledo S, Howell R, Fromm M, Azzam E. Nontargeted stressful effects in normal human fibroblast cultures exposed to low fluences of high charge, high energy (HZE) particles: kinetics of biologic responses and significance of secondary radiations. Radiat Res. 2013;179:444-57 pubmed 出版商
Lau R, Niu M, Pratt M. cIAP2 represses IKK?/?-mediated activation of MDM2 to prevent p53 degradation. Cell Cycle. 2012;11:4009-19 pubmed 出版商
Oga A, Uchida K, Nakao M, Kawauchi S, Furuya T, Chochi Y, et al. Loss of 6q or 8p23 is associated with the total number of DNA copy number aberrations in adenoid cystic carcinoma. Oncol Rep. 2011;26:1393-8 pubmed 出版商
Zhang L, Sun S, Zhou J, Liu J, Lv J, Yu X, et al. Knockdown of Akt1 promotes Akt2 upregulation and resistance to oxidative-stress-induced apoptosis through control of multiple signaling pathways. Antioxid Redox Signal. 2011;15:1-17 pubmed 出版商
Mukhopadhyay U, Mooney P, Jia L, Eves R, Raptis L, Mak A. Doubles game: Src-Stat3 versus p53-PTEN in cellular migration and invasion. Mol Cell Biol. 2010;30:4980-95 pubmed 出版商
Mukhopadhyay U, Eves R, Jia L, Mooney P, Mak A. p53 suppresses Src-induced podosome and rosette formation and cellular invasiveness through the upregulation of caldesmon. Mol Cell Biol. 2009;29:3088-98 pubmed 出版商
Widenmaier S, Sampaio A, Underhill T, McIntosh C. Noncanonical activation of Akt/protein kinase B in {beta}-cells by the incretin hormone glucose-dependent insulinotropic polypeptide. J Biol Chem. 2009;284:10764-73 pubmed 出版商
Shiraishi T, Nielsen P. Down-regulation of MDM2 and activation of p53 in human cancer cells by antisense 9-aminoacridine-PNA (peptide nucleic acid) conjugates. Nucleic Acids Res. 2004;32:4893-902 pubmed
Fujioka S, Schmidt C, Sclabas G, Li Z, Pelicano H, Peng B, et al. Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB. J Biol Chem. 2004;279:27549-59 pubmed
Picksley S, Vojtesek B, Sparks A, Lane D. Immunochemical analysis of the interaction of p53 with MDM2;--fine mapping of the MDM2 binding site on p53 using synthetic peptides. Oncogene. 1994;9:2523-9 pubmed
Hickman E, Picksley S, Vousden K. Cells expressing HPV16 E7 continue cell cycle progression following DNA damage induced p53 activation. Oncogene. 1994;9:2177-81 pubmed
Martin K, Trouche D, Hagemeier C, Sørensen T, La Thangue N, Kouzarides T. Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein. Nature. 1995;375:691-4 pubmed
产品信息
Product No. :
M4308
产品名称 :
单克隆抗鼠双微基因2在小鼠生产的抗体
宿主 :
小鼠
共轭标签 :
未共轭
抗体类型 :
单克隆
Clone Number (if monoclonal) :
SMP14
应用/描述 :
Suitable for immunocytochemistry; western blot: 1:1,000 using a whole extract of transfected 293T (human embryonal kidney) cells expressing human MDM2; microarray; indirect ELISA; immunoprecipitation (IP); immunohistochemistry (froze
物种活性 :
rat, human, mouse (weak)
抗体亚型 :
IgG1
储存 :
存放在-20°C
更多信息或购买 :
公司信息
西格玛奥德里奇
上海市徐汇区淮海中路1010号嘉华中心41楼
techservCN@sial.com
http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
公司总部: 美国
Sigma-Aldrich是一家在生命科学领域领先的且拥有高科技产品的公司,致力于为生命科学、制药化工等领域提供高质量的服务和产品。