出版应用/物种/样本/稀释 | 参考文献 |
---|
| Haag A, Walser M, Henggeler A, Hajnal A. The CHORD protein CHP-1 regulates EGF receptor trafficking and signaling in C. elegans and in human cells. elife. 2020;9: pubmed 出版商
|
- 免疫印迹; 人类; 1:10,000; 图 s1b
| Kennedy S, Jarboui M, Srihari S, Raso C, Bryan K, Dernayka L, et al. Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D. Nat Commun. 2020;11:499 pubmed 出版商
|
| Olivares O, Mayers J, Gouirand V, Torrence M, Gicquel T, Borge L, et al. Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions. Nat Commun. 2017;8:16031 pubmed 出版商
|
| Lopes M, Leal R, Guarnieri R, Schwarzbold M, Hoeller A, Diaz A, et al. A single high dose of dexamethasone affects the phosphorylation state of glutamate AMPA receptors in the human limbic system. Transl Psychiatry. 2016;6:e986 pubmed 出版商
|
| Yang H, Vainshtein A, Maik Rachline G, Peles E. G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination. Nat Commun. 2016;7:10884 pubmed 出版商
|
| Bigenzahn J, Fauster A, Rebsamen M, Kandasamy R, Scorzoni S, Vladimer G, et al. An Inducible Retroviral Expression System for Tandem Affinity Purification Mass-Spectrometry-Based Proteomics Identifies Mixed Lineage Kinase Domain-like Protein (MLKL) as an Heat Shock Protein 90 (HSP90) Client. Mol Cell Proteomics. 2016;15:1139-50 pubmed
|
| Stefanovic M, Tutusaus A, Martinez Nieto G, Bárcena C, de Gregorio E, Moutinho C, et al. Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma. Oncotarget. 2016;7:8253-67 pubmed 出版商
|
- 免疫印迹; 大鼠; 1:40,000; 图 s2a
| Peres T, Ong L, Costa A, Eyng H, Venske D, Colle D, et al. Tyrosine hydroxylase regulation in adult rat striatum following short-term neonatal exposure to manganese. Metallomics. 2016;8:597-604 pubmed 出版商
|
| Inamdar V, Reddy H, Dangelmaier C, Kostyak J, Kunapuli S. The protein tyrosine phosphatase PTPN7 is a negative regulator of ERK activation and thromboxane generation in platelets. J Biol Chem. 2019;294:12547-12554 pubmed 出版商
|
| Sumi N, Ctortecka C, Hu Q, Bryant A, Fang B, Remsing Rix L, et al. Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets. Cell Chem Biol. 2019;26:1240-1252.e11 pubmed 出版商
|
| Zingkou E, Pampalakis G, Charla E, Nauroy P, Kiritsi D, Sotiropoulou G. A proinflammatory role of KLK6 protease in Netherton syndrome. J Dermatol Sci. 2019;95:28-35 pubmed 出版商
|
| Thotakura S, Basova L, Makarenkova H. FGF Gradient Controls Boundary Position Between Proliferating and Differentiating Cells and Regulates Lacrimal Gland Growth Dynamics. Front Genet. 2019;10:362 pubmed 出版商
|
| Liu S, Xing Y, Wang J, Pan R, Li G, Tang H, et al. The Dual Role of HIV-1 gp120 V3 Loop-Induced Autophagy in the Survival and Apoptosis of the Primary Rat Hippocampal Neurons. Neurochem Res. 2019;44:1636-1652 pubmed 出版商
|
| Ning S, Wang Z, Cao J, Dong Y, Chen Y. Mel1c Mediated Monochromatic Light-Stimulated IGF-I Synthesis through the Intracellular Gαq/PKC/ERK Signaling Pathway. Int J Mol Sci. 2019;20: pubmed 出版商
|
| Castany S, Codony X, Zamanillo D, Merlos M, Verdú E, Boadas Vaello P. Repeated Sigma-1 Receptor Antagonist MR309 Administration Modulates Central Neuropathic Pain Development After Spinal Cord Injury in Mice. Front Pharmacol. 2019;10:222 pubmed 出版商
|
| Tsai C, Kuo F, Lee S, Chang Y, Fu H. Endocytosis-dependent lysosomal degradation of Src induced by protease-activated receptor 1. FEBS Lett. 2019;593:504-517 pubmed 出版商
|
| Bunda S, Heir P, Metcalf J, Li A, Agnihotri S, Pusch S, et al. CIC protein instability contributes to tumorigenesis in glioblastoma. Nat Commun. 2019;10:661 pubmed 出版商
|
| Colle D, Santos D, de Souza V, Lopes M, Leal R, de Souza Brocardo P, et al. Sodium selenite protects from 3-nitropropionic acid-induced oxidative stress in cultured primary cortical neurons. Mol Biol Rep. 2019;46:751-762 pubmed 出版商
|
| Arbel Rubinstein T, Shahmoon S, Zigmond E, Etan T, Merenbakh Lamin K, Pasmanik Chor M, et al. Klotho suppresses colorectal cancer through modulation of the unfolded protein response. Oncogene. 2019;38:794-807 pubmed 出版商
|
| Rosenberg L, Cattin A, Fontana X, Harford Wright E, Burden J, White I, et al. HDAC3 Regulates the Transition to the Homeostatic Myelinating Schwann Cell State. Cell Rep. 2018;25:2755-2765.e5 pubmed 出版商
|
| Fernández Espartero C, Rizzo A, Fulford A, Falo Sanjuan J, Goutte Gattat D, Ribeiro P. Prp8 regulates oncogene-induced hyperplastic growth in Drosophila. Development. 2018;145: pubmed 出版商
|
| Del Rio C, Cantarero I, Palomares B, Gómez Cañas M, Fernandez Ruiz J, Pavicic C, et al. VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPARγ- and CB2 receptor-dependent pathways. Br J Pharmacol. 2018;175:3813-3831 pubmed 出版商
|
| Rukhlenko O, Khorsand F, Krstic A, Rožanc J, Alexopoulos L, Rauch N, et al. Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling. Cell Syst. 2018;7:161-179.e14 pubmed 出版商
|
| Duan L, Ye L, Zhuang L, Zou X, Liu S, Zhang Y, et al. VEGFC/VEGFR3 axis mediates TGFβ1-induced epithelial-to-mesenchymal transition in non-small cell lung cancer cells. PLoS ONE. 2018;13:e0200452 pubmed 出版商
|
| Higa T, Takahashi H, Higa Nakamine S, Suzuki M, Yamamoto H. Up-regulation of DUSP5 and DUSP6 by gonadotropin-releasing hormone in cultured hypothalamic neurons, GT1-7 cells. Biomed Res. 2018;39:149-158 pubmed 出版商
|
| Rozenbaum M, Rajman M, Rishal I, Koppel I, Koley S, Medzihradszky K, et al. Translatome Regulation in Neuronal Injury and Axon Regrowth. Eneuro. 2018;5: pubmed 出版商
|
| Zahavi E, Steinberg N, Altman T, Chein M, Joshi Y, Gradus Pery T, et al. The receptor tyrosine kinase TrkB signals without dimerization at the plasma membrane. Sci Signal. 2018;11: pubmed 出版商
|
| Brohée L, Peulen O, Nusgens B, Castronovo V, Thiry M, Colige A, et al. Propranolol sensitizes prostate cancer cells to glucose metabolism inhibition and prevents cancer progression. Sci Rep. 2018;8:7050 pubmed 出版商
|
| Shiloh R, Gilad Y, Ber Y, Eisenstein M, Aweida D, Bialik S, et al. Non-canonical activation of DAPK2 by AMPK constitutes a new pathway linking metabolic stress to autophagy. Nat Commun. 2018;9:1759 pubmed 出版商
|
| Chen J, Cao Z, Guan J. SHP2 inhibitor PHPS1 protects against atherosclerosis by inhibiting smooth muscle cell proliferation. BMC Cardiovasc Disord. 2018;18:72 pubmed 出版商
|
| Majorini M, Manenti G, Mano M, De Cecco L, Conti A, Pinciroli P, et al. cIAP1 regulates the EGFR/Snai2 axis in triple-negative breast cancer cells. Cell Death Differ. 2018;25:2147-2164 pubmed 出版商
|
| Jia Y, Zhang C, Hu C, Yu Y, Zheng X, Li Y, et al. EGFR inhibition enhances the antitumor efficacy of a selective BRAF V600E inhibitor in thyroid cancer cell lines. Oncol Lett. 2018;15:6763-6769 pubmed 出版商
|
| Goyal R, Tulpan D, Chomistek N, González Peña Fundora D, West C, Ellis B, et al. Analysis of MAPK and MAPKK gene families in wheat and related Triticeae species. BMC Genomics. 2018;19:178 pubmed 出版商
|
| Castany S, Gris G, Vela J, Verdú E, Boadas Vaello P. Critical role of sigma-1 receptors in central neuropathic pain-related behaviours after mild spinal cord injury in mice. Sci Rep. 2018;8:3873 pubmed 出版商
|
| Zhou J, Hu Q, Zhang X, Zheng J, Xie B, Xu Z, et al. Sensitivity to chemotherapeutics of NSCLC cells with acquired resistance to EGFR-TKIs is mediated by T790M mutation or epithelial-mesenchymal transition. Oncol Rep. 2018;39:1783-1792 pubmed 出版商
|
| Zhou D, Fu H, Xiao L, Mo H, Zhuo H, Tian X, et al. Fibroblast-Specific β-Catenin Signaling Dictates the Outcome of AKI. J Am Soc Nephrol. 2018;29:1257-1271 pubmed 出版商
|
| Dong F, Liu T, Jin H, Wang W. Chimaphilin inhibits human osteosarcoma cell invasion and metastasis through suppressing the TGF-β1-induced epithelial-to-mesenchymal transition markers via PI-3K/Akt, ERK1/2, and Smad signaling pathways. Can J Physiol Pharmacol. 2018;96:1-7 pubmed 出版商
|
| Wilson C, Nimick M, Nehoff H, Ashton J. ALK and IGF-1R as independent targets in crizotinib resistant lung cancer. Sci Rep. 2017;7:13955 pubmed 出版商
|
| Wang Z, Zhang F, He J, Wu P, Tay L, Cai M, et al. Binding of PLD2-Generated Phosphatidic Acid to KIF5B Promotes MT1-MMP Surface Trafficking and Lung Metastasis of Mouse Breast Cancer Cells. Dev Cell. 2017;43:186-197.e7 pubmed 出版商
|
| Zhao J, Zhao J, Xu G, Wang Z, Gao J, Cui S, et al. Deletion of Spata2 by CRISPR/Cas9n causes increased inhibin alpha expression and attenuated fertility in male mice. Biol Reprod. 2017;97:497-513 pubmed 出版商
|
| Bluemn E, Coleman I, Lucas J, Coleman R, Hernández López S, Tharakan R, et al. Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling. Cancer Cell. 2017;32:474-489.e6 pubmed 出版商
|
| Kuenzi B, Remsing Rix L, Stewart P, Fang B, Kinose F, Bryant A, et al. Polypharmacology-based ceritinib repurposing using integrated functional proteomics. Nat Chem Biol. 2017;13:1222-1231 pubmed 出版商
|
| Shih C, Chang Y, Huang W, Jang T, Kung H, Wang W, et al. EZH2-mediated upregulation of ROS1 oncogene promotes oral cancer metastasis. Oncogene. 2017;36:6542-6554 pubmed 出版商
|
| Innamorati G, Fontana E, Steccanella F, Gandhi K, Bassi G, Zandonà V, et al. Pleiotropic effects of sphingosine-1-phosphate signaling to control human chorionic mesenchymal stem cell physiology. Cell Death Dis. 2017;8:e2930 pubmed 出版商
|
| Yoon S, Kovalenko A, Bogdanov K, Wallach D. MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation. Immunity. 2017;47:51-65.e7 pubmed 出版商
|
| Agron M, Brekhman V, Morgenstern D, Lotan T. Regulation of AP-1 by MAPK Signaling in Metal-Stressed Sea Anemone. Cell Physiol Biochem. 2017;42:952-964 pubmed 出版商
|
| Gamage T, Anderson J, Abood M. CB1 allosteric modulator Org27569 is an antagonist/inverse agonist of ERK1/2 signaling. Cannabis Cannabinoid Res. 2016;1:272-280 pubmed 出版商
|
| Sobral L, Coletta R, Alberici L, Curti C, Leopoldino A. SET/I2PP2A overexpression induces phenotypic, molecular, and metabolic alterations in an oral keratinocyte cell line. FEBS J. 2017;284:2774-2785 pubmed 出版商
|
| Suisse A, He D, Legent K, Treisman J. COP9 signalosome subunits protect Capicua from MAPK-dependent and -independent mechanisms of degradation. Development. 2017;144:2673-2682 pubmed 出版商
|
| Rives Quinto N, Franco M, de Torres Jurado A, Carmena A. Synergism between canoe and scribble mutations causes tumor-like overgrowth via Ras activation in neural stem cells and epithelia. Development. 2017;144:2570-2583 pubmed 出版商
|
| Plössl K, Royer M, Bernklau S, Tavraz N, Friedrich T, Wild J, et al. Retinoschisin is linked to retinal Na/K-ATPase signaling and localization. Mol Biol Cell. 2017;28:2178-2189 pubmed 出版商
|
| Aquino Martínez R, Artigas N, Gámez B, Rosa J, Ventura F. Extracellular calcium promotes bone formation from bone marrow mesenchymal stem cells by amplifying the effects of BMP-2 on SMAD signalling. PLoS ONE. 2017;12:e0178158 pubmed 出版商
|
| Balczon R, Morrow K, Zhou C, Edmonds B, Alexeyev M, Pittet J, et al. Pseudomonas aeruginosa infection liberates transmissible, cytotoxic prion amyloids. FASEB J. 2017;31:2785-2796 pubmed 出版商
|
| Kwon S, An S, Kim M, Kim K, Choi Y, Ahn K, et al. Phytosphingosine-1-phosphate and epidermal growth factor synergistically restore extracellular matrix in human dermal fibroblasts in vitro and in vivo. Int J Mol Med. 2017;39:741-748 pubmed 出版商
|
| Duffy D, Krstic A, Halasz M, Schwarzl T, Konietzny A, Iljin K, et al. Retinoic acid and TGF-? signalling cooperate to overcome MYCN-induced retinoid resistance. Genome Med. 2017;9:15 pubmed 出版商
|
| Steinhauer J. Co-culture Activation of MAP Kinase in Drosophila S2 Cells. Methods Mol Biol. 2017;1487:235-241 pubmed
|
| Wang Y, Li D, Luo J, Tian G, Zhao L, Liao D. Intrinsic cellular signaling mechanisms determine the sensitivity of cancer cells to virus-induced apoptosis. Sci Rep. 2016;6:37213 pubmed 出版商
|
| Rieger D, Navarro E, Buendia I, Parada E, González Lafuente L, Leon R, et al. ConBr, A Lectin Purified from the Seeds of Canavalia brasiliensis, Protects Against Ischemia in Organotypic Culture of Rat Hippocampus: Potential Implication of Voltage-Gated Calcium Channels. Neurochem Res. 2017;42:347-359 pubmed 出版商
|
| Hoffmann H, Crouzin N, Moreno E, Raivio N, Fuentes S, McCormick P, et al. Long-Lasting Impairment of mGluR5-Activated Intracellular Pathways in the Striatum After Withdrawal of Cocaine Self-Administration. Int J Neuropsychopharmacol. 2017;20:72-82 pubmed 出版商
|
| Fu H, Tian Y, Zhou L, Zhou D, Tan R, Stolz D, et al. Tenascin-C Is a Major Component of the Fibrogenic Niche in Kidney Fibrosis. J Am Soc Nephrol. 2017;28:785-801 pubmed 出版商
|
| Abramovitch Dahan C, Asraf H, Bogdanovic M, Sekler I, Bush A, Hershfinkel M. Amyloid ? attenuates metabotropic zinc sensing receptor, mZnR/GPR39, dependent Ca2+ , ERK1/2 and Clusterin signaling in neurons. J Neurochem. 2016;139:221-233 pubmed 出版商
|
| Kamei M, Yamashita K, Takahashi M, Fukumori F, Ichiishi A, Fujimura M. Involvement of MAK-1 and MAK-2 MAP kinases in cell wall integrity in Neurospora crassa. Biosci Biotechnol Biochem. 2016;80:1843-52 pubmed 出版商
|
| PETRUCCELLI E, Li Q, Rao Y, Kitamoto T. The Unique Dopamine/Ecdysteroid Receptor Modulates Ethanol-Induced Sedation in Drosophila. J Neurosci. 2016;36:4647-57 pubmed 出版商
|
| Komla Ebri D, Dambroise E, Kramer I, Benoist Lasselin C, Kaci N, Le Gall C, et al. Tyrosine kinase inhibitor NVP-BGJ398 functionally improves FGFR3-related dwarfism in mouse model. J Clin Invest. 2016;126:1871-84 pubmed 出版商
|
| Keravis T, Favot L, Abusnina A, Anton A, Justiniano H, Soleti R, et al. Delphinidin Inhibits Tumor Growth by Acting on VEGF Signalling in Endothelial Cells. PLoS ONE. 2015;10:e0145291 pubmed 出版商
|
| Bunda S, Burrell K, Heir P, Zeng L, Alamsahebpour A, Kano Y, et al. Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis. Nat Commun. 2015;6:8859 pubmed 出版商
|
| Gershoni Emek N, Mazza A, Chein M, Gradus Pery T, Xiang X, Li K, et al. Proteomic Analysis of Dynein-Interacting Proteins in Amyotrophic Lateral Sclerosis Synaptosomes Reveals Alterations in the RNA-Binding Protein Staufen1. Mol Cell Proteomics. 2016;15:506-22 pubmed 出版商
|
| Shukla P, Vogl C, Wallner B, Rigler D, Müller M, Macho Maschler S. High-throughput mRNA and miRNA profiling of epithelial-mesenchymal transition in MDCK cells. BMC Genomics. 2015;16:944 pubmed 出版商
|
| Higa Nakamine S, Maeda N, Toku S, Yamamoto H. Involvement of Protein Kinase D1 in Signal Transduction from the Protein Kinase C Pathway to the Tyrosine Kinase Pathway in Response to Gonadotropin-releasing Hormone. J Biol Chem. 2015;290:25974-85 pubmed 出版商
|
| Jovasevic V, Corcoran K, Leaderbrand K, Yamawaki N, Guedea A, Chen H, et al. GABAergic mechanisms regulated by miR-33 encode state-dependent fear. Nat Neurosci. 2015;18:1265-71 pubmed 出版商
|
| Schmid T, Snoek L, Fröhli E, van der Bent M, Kammenga J, Hajnal A. Systemic Regulation of RAS/MAPK Signaling by the Serotonin Metabolite 5-HIAA. PLoS Genet. 2015;11:e1005236 pubmed 出版商
|
| Zhang X, Liang D, Chi Z, Chu Q, Zhao C, Ma R, et al. Effect of zinc on high glucose-induced epithelial-to-mesenchymal transition in renal tubular epithelial cells. Int J Mol Med. 2015;35:1747-54 pubmed 出版商
|
| Brohée L, Demine S, Willems J, Arnould T, Colige A, Deroanne C. Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment. Oncotarget. 2015;6:11264-80 pubmed
|
| Kondapalli K, Llongueras J, Capilla González V, Prasad H, Hack A, Smith C, et al. A leak pathway for luminal protons in endosomes drives oncogenic signalling in glioblastoma. Nat Commun. 2015;6:6289 pubmed 出版商
|
| Zahavi E, Ionescu A, Gluska S, Gradus T, Ben Yaakov K, Perlson E. A compartmentalized microfluidic neuromuscular co-culture system reveals spatial aspects of GDNF functions. J Cell Sci. 2015;128:1241-52 pubmed 出版商
|
| Leibovich Rivkin T, Liubomirski Y, Meshel T, Abashidze A, Brisker D, Solomon H, et al. The inflammatory cytokine TNF? cooperates with Ras in elevating metastasis and turns WT-Ras to a tumor-promoting entity in MCF-7 cells. BMC Cancer. 2014;14:158 pubmed 出版商
|