产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
FLUKA, Sigma-Aldrich, Roche Applied Science
产品类型 :
抗体
产品名称 :
Monoclonal Anti-AGO2 antibody produced in rat
目录 :
SAB4200085
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
11A9
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 核糖核酸免疫沉淀, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 42
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 2d
Li Y, Wang L, Rivera Serrano E, Chen X, Lemon S. TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA. Nucleic Acids Res. 2019;47:6411-6424 pubmed 出版商
  • 免疫印迹; 人类; 图 s3g, 3b, 3c, s3a
Jeppesen D, Fenix A, Franklin J, Higginbotham J, Zhang Q, Zimmerman L, et al. Reassessment of Exosome Composition. Cell. 2019;177:428-445.e18 pubmed 出版商
  • 免疫沉淀; 大鼠; 图 4h
Periyasamy P, Liao K, Kook Y, Niu F, Callen S, Guo M, et al. Cocaine-Mediated Downregulation of miR-124 Activates Microglia by Targeting KLF4 and TLR4 Signaling. Mol Neurobiol. 2018;55:3196-3210 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 4c
  • 染色质免疫沉淀 ; 人类; 图 3a
van Eijl R, van den Brand T, Nguyen L, Mulder K. Reactivity of human AGO2 monoclonal antibody 11A9 with the SWI/SNF complex: A case study for rigorously defining antibody selectivity. Sci Rep. 2017;7:7278 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 s3a
Golden R, Chen B, Li T, Braun J, Manjunath H, Chen X, et al. An Argonaute phosphorylation cycle promotes microRNA-mediated silencing. Nature. 2017;542:197-202 pubmed 出版商
  • 免疫沉淀; 人类; 图 4
Rasmussen M, Lyskjær I, Jersie Christensen R, Tarpgaard L, Primdal Bengtson B, Nielsen M, et al. miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells. Nat Commun. 2016;7:12436 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 4b
Miyazaki Y, Du X, Muramatsu S, Gomez C. An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron. Sci Transl Med. 2016;8:347ra94 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s8
Salzman D, Nakamura K, Nallur S, Dookwah M, Metheetrairut C, Slack F, et al. miR-34 activity is modulated through 5'-end phosphorylation in response to DNA damage. Nat Commun. 2016;7:10954 pubmed 出版商
  • 核糖核酸免疫沉淀; 人类
Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016;61:903-13 pubmed 出版商
  • 免疫印迹; 人类; 图 2c
van Buggenum J, Gerlach J, Eising S, Schoonen L, van Eijl R, Tanis S, et al. A covalent and cleavable antibody-DNA conjugation strategy for sensitive protein detection via immuno-PCR. Sci Rep. 2016;6:22675 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫印迹; 小鼠
Boudoukha S, Rivera Vargas T, Dang I, Kropp J, Cuvellier S, Gautreau A, et al. MiRNA let-7g regulates skeletal myoblast motility via Pinch-2. FEBS Lett. 2014;588:1623-9 pubmed 出版商
Qiu N, Xu X, He Y. LncRNA TUG1 alleviates sepsis-induced acute lung injury by targeting miR-34b-5p/GAB1. BMC Pulm Med. 2020;20:49 pubmed 出版商
Yang Q, Li R, Lyu Q, Hou L, Liu Z, Sun Q, et al. Single-cell CAS-seq reveals a class of short PIWI-interacting RNAs in human oocytes. Nat Commun. 2019;10:3389 pubmed 出版商
Most D, Salem N, Tiwari G, Blednov Y, Mayfield R, Harris R. Silencing synaptic MicroRNA-411 reduces voluntary alcohol consumption in mice. Addict Biol. 2019;24:604-616 pubmed 出版商
Nowakowski T, Rani N, Golkaram M, Zhou H, Alvarado B, Huch K, et al. Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development. Nat Neurosci. 2018;21:1784-1792 pubmed 出版商
Kutsche L, Gysi D, Fallmann J, Lenk K, Petri R, Swiersy A, et al. Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis. Cell Syst. 2018;7:438-452.e8 pubmed 出版商
Periyasamy P, Thangaraj A, Guo M, Hu G, Callen S, Buch S. Epigenetic Promoter DNA Methylation of miR-124 Promotes HIV-1 Tat-Mediated Microglial Activation via MECP2-STAT3 Axis. J Neurosci. 2018;38:5367-5383 pubmed 出版商
Ottaviani S, Stebbing J, Frampton A, Zagorac S, Krell J, de Giorgio A, et al. TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression. Nat Commun. 2018;9:1845 pubmed 出版商
Zhang T, Wu Y, Mullane P, Ji Y, Liu H, He L, et al. FUS Regulates Activity of MicroRNA-Mediated Gene Silencing. Mol Cell. 2018;69:787-801.e8 pubmed 出版商
Lee Y, Bernstock J, Klimanis D, Hallenbeck J. Akt Protein Kinase, miR-200/miR-182 Expression and Epithelial-Mesenchymal Transition Proteins in Hibernating Ground Squirrels. Front Mol Neurosci. 2018;11:22 pubmed 出版商
Awan H, Shah A, Rashid F, Wei S, Chen L, Shan G. Comparing two approaches of miR-34a target identification, biotinylated-miRNA pulldown vs miRNA overexpression. RNA Biol. 2017;:1-7 pubmed 出版商
Sahoo M, Gaikwad S, Khuperkar D, Ashok M, Helen M, Yadav S, et al. Nup358 binds to AGO proteins through its SUMO-interacting motifs and promotes the association of target mRNA with miRISC. EMBO Rep. 2017;18:241-263 pubmed 出版商
Deforzh E, Vargas T, Kropp J, Vandamme M, Pinna G, Polesskaya A. IMP-3 protects the mRNAs of cyclins D1 and D3 from GW182/AGO2-dependent translational repression. Int J Oncol. 2016;49:2578-2588 pubmed 出版商
Ouyang Y, Bayer A, Chu T, Tyurin V, Kagan V, Morelli A, et al. Isolation of human trophoblastic extracellular vesicles and characterization of their cargo and antiviral activity. Placenta. 2016;47:86-95 pubmed 出版商
Dasgupta N, Peng Y, Tan Z, Ciraolo G, Wang D, Li R. miRNAs in mtDNA-less cell mitochondria. Cell Death Discov. 2015;1:15004 pubmed 出版商
Huang C, Wang X, Liu X, Cao S, Shan G. RNAi pathway participates in chromosome segregation in mammalian cells. Cell Discov. 2015;1:15029 pubmed 出版商
Angart P, Carlson R, Adu Berchie K, Walton S. Terminal Duplex Stability and Nucleotide Identity Differentially Control siRNA Loading and Activity in RNA Interference. Nucleic Acid Ther. 2016;26:309-317 pubmed
Kratassiouk G, Pritchard L, Cuvellier S, Vislovukh A, Meng Q, Groisman R, et al. The WEE1 regulators CPEB1 and miR-15b switch from inhibitor to activators at G2/M. Cell Cycle. 2016;15:667-77 pubmed 出版商
Krell J, Stebbing J, Carissimi C, Dabrowska A, de Giorgio A, Frampton A, et al. TP53 regulates miRNA association with AGO2 to remodel the miRNA-mRNA interaction network. Genome Res. 2016;26:331-41 pubmed 出版商
Durruthy Durruthy J, Sebastiano V, Wossidlo M, Cepeda D, Cui J, Grow E, et al. The primate-specific noncoding RNA HPAT5 regulates pluripotency during human preimplantation development and nuclear reprogramming. Nat Genet. 2016;48:44-52 pubmed 出版商
Nixon B, Stanger S, Mihalas B, Reilly J, Anderson A, Dun M, et al. Next Generation Sequencing Analysis Reveals Segmental Patterns of microRNA Expression in Mouse Epididymal Epithelial Cells. PLoS ONE. 2015;10:e0135605 pubmed 出版商
Abuhatzira L, Xu H, Tahhan G, Boulougoura A, Schäffer A, Notkins A. Multiple microRNAs within the 14q32 cluster target the mRNAs of major type 1 diabetes autoantigens IA-2, IA-2β, and GAD65. FASEB J. 2015;29:4374-83 pubmed 出版商
Lewkowicz P, CwikliÅ„ska H, Mycko M, Cichalewska M, Domowicz M, Lewkowicz N, et al. Dysregulated RNA-Induced Silencing Complex (RISC) Assembly within CNS Corresponds with Abnormal miRNA Expression during Autoimmune Demyelination. J Neurosci. 2015;35:7521-37 pubmed 出版商
Mukherjee A, Di Bisceglie A, Ray R. Hepatitis C virus-mediated enhancement of microRNA miR-373 impairs the JAK/STAT signaling pathway. J Virol. 2015;89:3356-65 pubmed 出版商
Seto E, Inoue T, Nakatani Y, Yamada M, Isomura H. Processing bodies accumulate in human cytomegalovirus-infected cells and do not affect viral replication at high multiplicity of infection. Virology. 2014;458-459:151-61 pubmed 出版商
Holla S, Kurowska Stolarska M, Bayry J, Balaji K. Selective inhibition of IFNG-induced autophagy by Mir155- and Mir31-responsive WNT5A and SHH signaling. Autophagy. 2014;10:311-30 pubmed 出版商
Roberts A, Doidge R, Tarr A, Jopling C. The P body protein LSm1 contributes to stimulation of hepatitis C virus translation, but not replication, by microRNA-122. Nucleic Acids Res. 2014;42:1257-69 pubmed 出版商
Nechaev S, Gao C, Moreira D, Swiderski P, Jóźwiak A, Kowolik C, et al. Intracellular processing of immunostimulatory CpG-siRNA: Toll-like receptor 9 facilitates siRNA dicing and endosomal escape. J Control Release. 2013;170:307-15 pubmed 出版商
Maurin T, Cazalla D, Yang S, Bortolamiol Becet D, Lai E. RNase III-independent microRNA biogenesis in mammalian cells. RNA. 2012;18:2166-73 pubmed 出版商
Turchinovich A, Burwinkel B. Distinct AGO1 and AGO2 associated miRNA profiles in human cells and blood plasma. RNA Biol. 2012;9:1066-75 pubmed 出版商
Rüdel S, Flatley A, Weinmann L, Kremmer E, Meister G. A multifunctional human Argonaute2-specific monoclonal antibody. RNA. 2008;14:1244-53 pubmed 出版商
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产品信息
Product No. :
SAB4200085
产品名称 :
Monoclonal Anti-AGO2 antibody produced in rat
宿主 :
大鼠
共轭标签 :
未共轭
抗体类型 :
单克隆
Clone Number (if monoclonal) :
11A9
应用/描述 :
Suitable for immunocytochemistry; western blot: 0.5-1.0 μg/mL using HeLa cell extracts; immunoprecipitation (IP)
物种活性 :
mouse, human, rat, monkey, bovine
抗体亚型 :
IgG2a
浓度 :
~1.5 mg/毫升
储存 :
存放在-20°C
更多信息或购买 :
公司信息
西格玛奥德里奇
上海市徐汇区淮海中路1010号嘉华中心41楼
techservCN@sial.com
http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
公司总部: 美国
Sigma-Aldrich是一家在生命科学领域领先的且拥有高科技产品的公司,致力于为生命科学、制药化工等领域提供高质量的服务和产品。