产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
FLUKA, Sigma-Aldrich, Roche Applied Science
产品类型 :
抗体
产品名称 :
单克隆抗核纤层蛋白A/C在小鼠生产的抗体
目录 :
SAB4200236
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4C11
反应物种 :
仓鼠, 人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 49
出版应用/物种/样本/稀释参考文献
  • 免疫印迹基因敲除验证; 小鼠; 图 1d
  • 免疫组化; 小鼠; 图 2a
  • 免疫印迹; 小鼠; 图 s1c
Wang W, Wang J, Lin W, Kao C, Hung M, Teng Y, et al. Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis. Aging Cell. 2020;19:e13090 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 5a
Peng J, Liang S, Li L. sFRP1 exerts effects on gastric cancer cells through GSK3β/Rac1‑mediated restraint of TGFβ/Smad3 signaling. Oncol Rep. 2019;41:224-234 pubmed 出版商
  • 免疫印迹; 仓鼠; 图 s19a
Tajik A, Zhang Y, Wei F, Sun J, Jia Q, Zhou W, et al. Transcription upregulation via force-induced direct stretching of chromatin. Nat Mater. 2016;15:1287-1296 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 1
Uribe M, Haro C, Ventero M, Campello L, Cruces J, Martín Nieto J. Expression pattern in retinal photoreceptors of POMGnT1, a protein involved in muscle-eye-brain disease. Mol Vis. 2016;22:658-73 pubmed
  • 免疫细胞化学; 小鼠; 1:2000; 图 5
Thiam H, Vargas P, Carpi N, Crespo C, Raab M, Terriac E, et al. Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments. Nat Commun. 2016;7:10997 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 7
Lindenboim L, Sasson T, Worman H, Borner C, Stein R. Cellular stress induces Bax-regulated nuclear bubble budding and rupture followed by nuclear protein release. Nucleus. 2014;5:527-41 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Jurkin J, Henkel T, Nielsen A, Minnich M, Popow J, Kaufmann T, et al. The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells. EMBO J. 2014;33:2922-36 pubmed 出版商
  • 免疫印迹; 人类
Hamada K, Osaka M, Yoshida M. Cell density impacts epigenetic regulation of cytokine-induced E-selectin gene expression in vascular endothelium. PLoS ONE. 2014;9:e90502 pubmed 出版商
Deng W, Bates J, Wei H, Bartoschek M, Conradt B, Leonhardt H. Tunable light and drug induced depletion of target proteins. Nat Commun. 2020;11:304 pubmed 出版商
Senfter D, Samadaei M, Mader R, Gojo J, Peyrl A, Krupitza G, et al. High impact of miRNA-4521 on FOXM1 expression in medulloblastoma. Cell Death Dis. 2019;10:696 pubmed 出版商
Tischbein M, Baron D, Lin Y, Gall K, Landers J, Fallini C, et al. The RNA-binding protein FUS/TLS undergoes calcium-mediated nuclear egress during excitotoxic stress and is required for GRIA2 mRNA processing. J Biol Chem. 2019;: pubmed 出版商
Fiserova J, Maninová M, Sieger T, Uhlířová J, Šebestová L, Efenberková M, et al. Nuclear pore protein TPR associates with lamin B1 and affects nuclear lamina organization and nuclear pore distribution. Cell Mol Life Sci. 2019;76:2199-2216 pubmed 出版商
Fichtman B, Zagairy F, Biran N, Barsheshet Y, Chervinsky E, Ben Neriah Z, et al. Combined loss of LAP1B and LAP1C results in an early onset multisystemic nuclear envelopathy. Nat Commun. 2019;10:605 pubmed 出版商
Kinterova V, Kanka J, Petruskova V, Toralova T. Inhibition of Skp1-Cullin-F-box complexes during bovine oocyte maturation and preimplantation development leads to delayed development of embryos†. Biol Reprod. 2019;100:896-906 pubmed 出版商
Li B, Chen J, Chao B, Zheng Y, Xiao X. A Lamin-Binding Ligand Inhibits Homologous Recombination Repair of DNA Double-Strand Breaks. ACS Cent Sci. 2018;4:1201-1210 pubmed 出版商
Barazeghi E, Prabhawa S, Norlén O, Hellman P, Stalberg P, Westin G. Decrease of 5-hydroxymethylcytosine and TET1 with nuclear exclusion of TET2 in small intestinal neuroendocrine tumors. BMC Cancer. 2018;18:764 pubmed 出版商
Bartova E, Legartova S, Krejci J, Řezníčková P, Kovaříková A, Suchankova J, et al. Depletion of A-type lamins and Lap2? reduces 53BP1 accumulation at UV-induced DNA lesions and Lap2? protein is responsible for compactness of irradiated chromatin. J Cell Biochem. 2018;: pubmed 出版商
Li B, Chen J, Chao B, David L, Xiao X. Anticancer Pyrroloquinazoline LBL1 Targets Nuclear Lamins. ACS Chem Biol. 2018;13:1380-1387 pubmed 出版商
Bossuet Greif N, Vignard J, Taïeb F, Mirey G, Dubois D, Petit C, et al. The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells. MBio. 2018;9: pubmed 出版商
Iradi M, Triplett J, Thomas J, Davila R, Crown A, Brown H, et al. Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy. Sci Rep. 2018;8:4049 pubmed 出版商
Bienkowska Haba M, Luszczek W, Myers J, Keiffer T, DiGiuseppe S, Polk P, et al. A new cell culture model to genetically dissect the complete human papillomavirus life cycle. PLoS Pathog. 2018;14:e1006846 pubmed 出版商
Stachecka J, Walczak A, Kociucka B, Ruszczycki B, Wilczynski G, Szczerbal I. Nuclear organization during in vitro differentiation of porcine mesenchymal stem cells (MSCs) into adipocytes. Histochem Cell Biol. 2018;149:113-126 pubmed 出版商
Kwon S, Chin K, NEDERLOF M, Gray J. Quantitative, in situ analysis of mRNAs and proteins with subcellular resolution. Sci Rep. 2017;7:16459 pubmed 出版商
Fiorito F, Iovane V, Cantiello A, Marullo A, De Martino L, Iovane G. MG-132 reduces virus release in Bovine herpesvirus-1 infection. Sci Rep. 2017;7:13306 pubmed 出版商
Pitaval A, Senger F, Letort G, Gidrol X, Guyon L, Sillibourne J, et al. Microtubule stabilization drives 3D centrosome migration to initiate primary ciliogenesis. J Cell Biol. 2017;216:3713-3728 pubmed 出版商
Harhouri K, Navarro C, Depetris D, Mattei M, Nissan X, Cau P, et al. MG132-induced progerin clearance is mediated by autophagy activation and splicing regulation. EMBO Mol Med. 2017;9:1294-1313 pubmed 出版商
. Muscle Pathology as a Diagnostic Clue to Allgrove Syndrome. J Neuropathol Exp Neurol. 2017;76:337-341 pubmed 出版商
Chan C, Li W, Cojoc G, Guck J. Volume Transitions of Isolated Cell Nuclei Induced by Rapid Temperature Increase. Biophys J. 2017;112:1063-1076 pubmed 出版商
Jansova D, Koncicka M, Tetkova A, Cerna R, Malik R, Del Llano E, et al. Regulation of 4E-BP1 activity in the mammalian oocyte. Cell Cycle. 2017;16:927-939 pubmed 出版商
Stultz R, Cenker J, McDonald D. Imaging HIV-1 Genomic DNA from Entry through Productive Infection. J Virol. 2017;91: pubmed 出版商
Bezine E, Malaisé Y, Loeuillet A, Chevalier M, Boutet Robinet E, Salles B, et al. Cell resistance to the Cytolethal Distending Toxin involves an association of DNA repair mechanisms. Sci Rep. 2016;6:36022 pubmed 出版商
Graillot V, Dormoy I, Dupuy J, Shay J, Huc L, Mirey G, et al. Genotoxicity of Cytolethal Distending Toxin (CDT) on Isogenic Human Colorectal Cell Lines: Potential Promoting Effects for Colorectal Carcinogenesis. Front Cell Infect Microbiol. 2016;6:34 pubmed 出版商
Schürmann M, Scholze J, MULLER P, Guck J, Chan C. Cell nuclei have lower refractive index and mass density than cytoplasm. J Biophotonics. 2016;9:1068-1076 pubmed 出版商
Leocadio D, Mitchell A, Winder S. ?-Secretase Dependent Nuclear Targeting of Dystroglycan. J Cell Biochem. 2016;117:2149-57 pubmed 出版商
Casasola A, Scalzo D, Nandakumar V, Halow J, Recillas Targa F, Groudine M, et al. Prelamin A processing, accumulation and distribution in normal cells and laminopathy disorders. Nucleus. 2016;7:84-102 pubmed 出版商
Versaevel M, Braquenier J, Riaz M, Grevesse T, Lantoine J, Gabriele S. Super-resolution microscopy reveals LINC complex recruitment at nuclear indentation sites. Sci Rep. 2014;4:7362 pubmed 出版商
Lee S, Song C, Xie Y, Jung C, Choi H, Lee K. SMILE upregulated by metformin inhibits the function of androgen receptor in prostate cancer cells. Cancer Lett. 2014;354:390-7 pubmed 出版商
Gonzalez Rodriguez A, Reibert B, Amann T, Constien R, Rondinone C, Valverde A. In vivo siRNA delivery of Keap1 modulates death and survival signaling pathways and attenuates concanavalin-A-induced acute liver injury in mice. Dis Model Mech. 2014;7:1093-100 pubmed 出版商
Panda S, Vedagiri D, Viveka T, Harshan K. A unique phosphorylation-dependent eIF4E assembly on 40S ribosomes co-ordinated by hepatitis C virus protein NS5A that activates internal ribosome entry site translation. Biochem J. 2014;462:291-302 pubmed 出版商
Kayman Kurekci G, Talim B, Korkusuz P, Sayar N, Sarioglu T, Oncel I, et al. Mutation in TOR1AIP1 encoding LAP1B in a form of muscular dystrophy: a novel gene related to nuclear envelopathies. Neuromuscul Disord. 2014;24:624-33 pubmed 出版商
Okamoto A, Asai T, Kato H, Ando H, Minamino T, Mekada E, et al. Antibody-modified lipid nanoparticles for selective delivery of siRNA to tumors expressing membrane-anchored form of HB-EGF. Biochem Biophys Res Commun. 2014;449:460-5 pubmed 出版商
Bertrand A, Ziaei S, Ehret C, Duchemin H, Mamchaoui K, Bigot A, et al. Cellular microenvironments reveal defective mechanosensing responses and elevated YAP signaling in LMNA-mutated muscle precursors. J Cell Sci. 2014;127:2873-84 pubmed 出版商
Camps J, Wangsa D, Falke M, Brown M, Case C, Erdos M, et al. Loss of lamin B1 results in prolongation of S phase and decondensation of chromosome territories. FASEB J. 2014;28:3423-34 pubmed 出版商
Chiu H, Hannemann H, Heesom K, Matthews D, Davidson A. High-throughput quantitative proteomic analysis of dengue virus type 2 infected A549 cells. PLoS ONE. 2014;9:e93305 pubmed 出版商
Hasan A, Ohmori K, Hashimoto T, Kamitori K, Yamaguchi F, Ishihara Y, et al. Valsartan ameliorates the constitutive adipokine expression pattern in mature adipocytes: a role for inverse agonism of the angiotensin II type 1 receptor in obesity. Hypertens Res. 2014;37:621-8 pubmed 出版商
Atik N, Kunii M, Avriyanti E, Furumoto N, Inami K, Yoshimura S, et al. The role of PKD in cell polarity, biosynthetic pathways, and organelle/F-actin distribution. Cell Struct Funct. 2014;39:61-77 pubmed
Drivas T, Holzbaur E, Bennett J. Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration. J Clin Invest. 2013;123:4525-39 pubmed 出版商
Hirano Y, Hizume K, Kimura H, Takeyasu K, Haraguchi T, Hiraoka Y. Lamin B receptor recognizes specific modifications of histone H4 in heterochromatin formation. J Biol Chem. 2012;287:42654-63 pubmed 出版商
Ruchaud S, Korfali N, Villa P, Kottke T, Dingwall C, Kaufmann S, et al. Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation. EMBO J. 2002;21:1967-77 pubmed
产品信息
Product No. :
SAB4200236
产品名称 :
单克隆抗核纤层蛋白A/C在小鼠生产的抗体
宿主 :
小鼠
共轭标签 :
未共轭
抗体类型 :
单克隆
Clone Number (if monoclonal) :
4C11
应用/描述 :
Suitable for immunoprecipitation (IP); western blot: 0.1-0.2 μg/mL using whole extracts of human HeLa cells; indirect immunofluorescence
物种活性 :
human, rat, canine, hamster, mouse, bovine, monkey
抗体亚型 :
IgG2a
浓度 :
~1.0 mg/毫升
储存 :
存放在-20°C
更多信息或购买 :
公司信息
西格玛奥德里奇
上海市徐汇区淮海中路1010号嘉华中心41楼
techservCN@sial.com
http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
公司总部: 美国
Sigma-Aldrich是一家在生命科学领域领先的且拥有高科技产品的公司,致力于为生命科学、制药化工等领域提供高质量的服务和产品。