产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
FLUKA, Sigma-Aldrich, Roche Applied Science
产品类型 :
抗体
产品名称 :
单克隆抗踝蛋白在小鼠生产的抗体
目录 :
T3287
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
8d4
反应物种 :
豚鼠, 仓鼠, 人类, 小鼠, 大鼠, , 非洲爪蛙
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 166
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 非洲爪蛙; 1:100; 图 1s2b
Chan Z, Kwan H, Wong Y, Jiang Z, Zhou Z, Tam K, et al. Site-directed MT1-MMP trafficking and surface insertion regulate AChR clustering and remodeling at developing NMJs. elife. 2020;9: pubmed 出版商
  • 免疫组化; 人类; 1:250; 图 3a
  • 免疫印迹; 人类; 1:2000; 图 3d
Bayer S, Grither W, Brenot A, Hwang P, Barcus C, Ernst M, et al. DDR2 controls breast tumor stiffness and metastasis by regulating integrin mediated mechanotransduction in CAFs. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 5b
Song K, Gras C, Capin G, Gimber N, Lehmann M, Mohd S, et al. A SEPT1-based scaffold is required for Golgi integrity and function. J Cell Sci. 2019;132: pubmed 出版商
  • 免疫印迹; 小鼠; 图 4g
Lin C, Zhang Y, Zhang K, Zheng Y, Lu L, Chang H, et al. Fever Promotes T Lymphocyte Trafficking via a Thermal Sensory Pathway Involving Heat Shock Protein 90 and α4 Integrins. Immunity. 2019;50:137-151.e6 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1a
Sun H, Lagarrigue F, Gingras A, Fan Z, Ley K, Ginsberg M. Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development. J Cell Biol. 2018;217:1453-1465 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4f
Margraf A, Nussbaum C, Rohwedder I, Klapproth S, Kurz A, Florian A, et al. Maturation of Platelet Function During Murine Fetal Development In Vivo. Arterioscler Thromb Vasc Biol. 2017;37:1076-1086 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4k
Georgiadou M, Lilja J, Jacquemet G, Guzmán C, Rafaeva M, Alibert C, et al. AMPK negatively regulates tensin-dependent integrin activity. J Cell Biol. 2017;216:1107-1121 pubmed 出版商
  • 免疫组化; 人类; 1:250; 图 st14
  • 免疫组化; 大鼠; 1:250; 图 st14
  • 免疫组化; 小鼠; 1:250; 图 st14
  • 免疫组化; 鸡; 1:250; 图 st14
Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s1d
Bharadwaj M, Strohmeyer N, Colo G, Helenius J, Beerenwinkel N, Schiller H, et al. αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin. Nat Commun. 2017;8:14348 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 3b
Zeng F, Xie Y, Liao L, Li L, Chen B, Xie J, et al. Biological characterization of three immortalized esophageal epithelial cell lines. Mol Med Rep. 2016;14:4802-4810 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1e
  • 免疫印迹; 人类; 图 9a
Kishi T, Mayanagi T, Iwabuchi S, Akasaka T, Sobue K. Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity. Oncotarget. 2016;7:72113-72130 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
Bouchet B, Gough R, Ammon Y, van de Willige D, Post H, Jacquemet G, et al. Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions. elife. 2016;5: pubmed 出版商
  • 免疫细胞化学; 豚鼠; 1:100; 图 1
  • 免疫印迹; 豚鼠; 1:1000; 图 1
Roa Espitia A, Hernández Rendón E, Baltiérrez Hoyos R, Muñoz Gotera R, Cote Vélez A, Jiménez I, et al. Focal adhesion kinase is required for actin polymerization and remodeling of the cytoskeleton during sperm capacitation. Biol Open. 2016;5:1189-99 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4
Cross A, Wilson A, Guerrero M, Thomas K, Bachir A, Kubow K, et al. Breast cancer antiestrogen resistance 3-p130Cas interactions promote adhesion disassembly and invasion in breast cancer cells. Oncogene. 2016;35:5850-5859 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s4
Elosegui Artola A, Oria R, Chen Y, Kosmalska A, Pérez González C, Castro N, et al. Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity. Nat Cell Biol. 2016;18:540-8 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 6d
  • 免疫印迹; 人类; 1:1000; 图 6a
Nader G, Ezratty E, Gundersen G. FAK, talin and PIPKI? regulate endocytosed integrin activation to polarize focal adhesion assembly. Nat Cell Biol. 2016;18:491-503 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 1
Theodosiou M, Widmaier M, Böttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s1
Atherton P, Stutchbury B, Wang D, Jethwa D, Tsang R, Meiler Rodriguez E, et al. Vinculin controls talin engagement with the actomyosin machinery. Nat Commun. 2015;6:10038 pubmed 出版商
  • 免疫印迹; 大鼠; 1:800; 图 2
Fiore V, Strane P, Bryksin A, White E, Hagood J, Barker T. Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction. J Cell Biol. 2015;211:173-90 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Roda D, Castillo J, Telechea Fernández M, Gil A, López Rodas G, Franco L, et al. EGF-Induced Acetylation of Heterogeneous Nuclear Ribonucleoproteins Is Dependent on KRAS Mutational Status in Colorectal Cancer Cells. PLoS ONE. 2015;10:e0130543 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4
Poulter N, Pollitt A, Davies A, Malinova D, Nash G, Hannon M, et al. Platelet actin nodules are podosome-like structures dependent on Wiskott-Aldrich syndrome protein and ARP2/3 complex. Nat Commun. 2015;6:7254 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
  • 免疫印迹; 人类; 1:500
Kiss A, Gong X, Kowalewski J, Shafqat Abbasi H, Strömblad S, Lock J. Non-monotonic cellular responses to heterogeneity in talin protein expression-level. Integr Biol (Camb). 2015;7:1171-85 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1
Robertson J, Jacquemet G, Byron A, Jones M, Warwood S, Selley J, et al. Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling. Nat Commun. 2015;6:6265 pubmed 出版商
  • 免疫印迹; 人类
Ng D, Humphries J, Byron A, Millon Frémillon A, Humphries M. Microtubule-dependent modulation of adhesion complex composition. PLoS ONE. 2014;9:e115213 pubmed 出版商
  • 免疫细胞化学; 人类
Uotila L, Jahan F, Soto Hinojosa L, Melandri E, Grönholm M, Gahmberg C. Specific phosphorylations transmit signals from leukocyte β2 to β1 integrins and regulate adhesion. J Biol Chem. 2014;289:32230-42 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Abramowski P, Ogrodowczyk C, Martin R, Pongs O. A truncation variant of the cation channel P2RX5 is upregulated during T cell activation. PLoS ONE. 2014;9:e104692 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Tseng H, Thorausch N, Ziegler T, Meves A, Fassler R, Böttcher R. Sorting nexin 31 binds multiple ? integrin cytoplasmic domains and regulates ?1 integrin surface levels and stability. J Mol Biol. 2014;426:3180-3194 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5, 7
Zemljic Harpf A, Godoy J, Platoshyn O, Asfaw E, Busija A, Domenighetti A, et al. Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes. J Cell Sci. 2014;127:1104-16 pubmed 出版商
  • 免疫印迹; 仓鼠; 1:2,000
Honda S, Shirotani Ikejima H, Tadokoro S, Tomiyama Y, Miyata T. The integrin-linked kinase-PINCH-parvin complex supports integrin ?IIb?3 activation. PLoS ONE. 2013;8:e85498 pubmed 出版商
van den Dries K, Nahidiazar L, Slotman J, Meddens M, Pandzic E, Joosten B, et al. Modular actin nano-architecture enables podosome protrusion and mechanosensing. Nat Commun. 2019;10:5171 pubmed 出版商
Stubb A, Guzman C, Närvä E, Aaron J, Chew T, Saari M, et al. Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells. Nat Commun. 2019;10:4756 pubmed 出版商
Wei H, Harper M. ABT-737 Triggers Caspase-Dependent Inhibition of Platelet Procoagulant Extracellular Vesicle Release during Apoptosis and Secondary Necrosis In Vitro. Thromb Haemost. 2019;119:1665-1674 pubmed 出版商
Buken C, Sahana J, Corydon T, Melnik D, Bauer J, Wehland M, et al. Morphological and Molecular Changes in Juvenile Normal Human Fibroblasts Exposed to Simulated Microgravity. Sci Rep. 2019;9:11882 pubmed 出版商
Sengupta S, Rothenberg K, Li H, Hoffman B, Bursac N. Altering integrin engagement regulates membrane localization of Kir2.1 channels. J Cell Sci. 2019;132: pubmed 出版商
Kumar A, Shutova M, Tanaka K, Iwamoto D, Calderwood D, Svitkina T, et al. Filamin A mediates isotropic distribution of applied force across the actin network. J Cell Biol. 2019;218:2481-2491 pubmed 出版商
Faust J, Balabiyev A, Heddleston J, Podolnikova N, Baluch D, Chew T, et al. An actin-based protrusion originating from a podosome-enriched region initiates macrophage fusion. Mol Biol Cell. 2019;30:2254-2267 pubmed 出版商
Peterková L, Rimpelová S, Slepicka P, Krízová I, Kasalkova N, Svorcik V, et al. Argon plasma-treated fluorinated ethylene propylene: Growth of primary dermal fibroblasts and mesenchymal stem cells. Tissue Cell. 2019;58:121-129 pubmed 出版商
Peterková L, Rimpelová S, Krízová I, Slepicka P, Kasalkova N, Svorcik V, et al. Biocompatibility of Ar plasma-treated fluorinated ethylene propylene: Adhesion and viability of human keratinocytes. Mater Sci Eng C Mater Biol Appl. 2019;100:269-275 pubmed 出版商
Bance B, Seetharaman S, Leduc C, Boëda B, Etienne Manneville S. Microtubule acetylation but not detyrosination promotes focal adhesion dynamics and astrocyte migration. J Cell Sci. 2019;: pubmed 出版商
Jacquemet G, Stubb A, Saup R, Miihkinen M, Kremneva E, Hamidi H, et al. Filopodome Mapping Identifies p130Cas as a Mechanosensitive Regulator of Filopodia Stability. Curr Biol. 2019;29:202-216.e7 pubmed 出版商
Hino N, Ichikawa T, Kimura Y, Matsuda M, Ueda K, Kioka N. An amphipathic helix of vinexin α is necessary for a substrate stiffness-dependent conformational change in vinculin. J Cell Sci. 2019;132: pubmed 出版商
Myllymäki S, Kämäräinen U, Liu X, Cruz S, Miettinen S, Vuorela M, et al. Assembly of the β4-Integrin Interactome Based on Proximal Biotinylation in the Presence and Absence of Heterodimerization. Mol Cell Proteomics. 2019;18:277-293 pubmed 出版商
Waldt N, Seifert A, Demiray Y, Devroe E, Turk B, Reichardt P, et al. Filamin A Phosphorylation at Serine 2152 by the Serine/Threonine Kinase Ndr2 Controls TCR-Induced LFA-1 Activation in T Cells. Front Immunol. 2018;9:2852 pubmed 出版商
Loh J, Lim T, Ikumi K, Matoba T, Janela B, Gunawan M, et al. Ezh2 Controls Skin Tolerance through Distinct Mechanisms in Different Subsets of Skin Dendritic Cells. iScience. 2018;10:23-39 pubmed 出版商
Gan W, Do O, Cottle L, Ma W, Kosobrodova E, Cooper White J, et al. Local Integrin Activation in Pancreatic ? Cells Targets Insulin Secretion to the Vasculature. Cell Rep. 2018;24:2819-2826.e3 pubmed 出版商
De Pascalis C, Pérez González C, Seetharaman S, Boëda B, Vianay B, Burute M, et al. Intermediate filaments control collective migration by restricting traction forces and sustaining cell-cell contacts. J Cell Biol. 2018;217:3031-3044 pubmed 出版商
Wei H, Malcor J, Harper M. Lipid rafts are essential for release of phosphatidylserine-exposing extracellular vesicles from platelets. Sci Rep. 2018;8:9987 pubmed 出版商
Atkinson S, Gontarczyk A, Alghamdi A, Ellison T, Johnson R, Fowler W, et al. The β3-integrin endothelial adhesome regulates microtubule-dependent cell migration. EMBO Rep. 2018;19: pubmed 出版商
Sauveur J, Matera E, Chettab K, Valet P, Guitton J, Savina A, et al. Esophageal cancer cells resistant to T-DM1 display alterations in cell adhesion and the prostaglandin pathway. Oncotarget. 2018;9:21141-21155 pubmed 出版商
Zhang W, Bhetwal B, Gunst S. Rho kinase collaborates with p21-activated kinase to regulate actin polymerization and contraction in airway smooth muscle. J Physiol. 2018;596:3617-3635 pubmed 出版商
Dix C, Matthews H, Uroz M, McLaren S, Wolf L, Heatley N, et al. The Role of Mitotic Cell-Substrate Adhesion Re-modeling in Animal Cell Division. Dev Cell. 2018;45:132-145.e3 pubmed 出版商
Maxson M, Naj X, O Meara T, Plumb J, Cowen L, Grinstein S. Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes. elife. 2018;7: pubmed 出版商
Goreczny G, Forsythe I, Turner C. Hic-5 regulates fibrillar adhesion formation to control tumor extracellular matrix remodeling through interaction with tensin1. Oncogene. 2018;37:1699-1713 pubmed 出版商
Burgstaller G, Sengupta A, Vierkotten S, Preissler G, Lindner M, Behr J, et al. Distinct niches within the extracellular matrix dictate fibroblast function in (cell free) 3D lung tissue cultures. Am J Physiol Lung Cell Mol Physiol. 2018;314:L708-L723 pubmed 出版商
Ruoss S, Möhl C, Benn M, von Rechenberg B, Wieser K, Meyer D, et al. Costamere protein expression and tissue composition of rotator cuff muscle after tendon release in sheep. J Orthop Res. 2018;36:272-281 pubmed 出版商
Elosegui Artola A, Andreu I, Beedle A, Lezamiz A, Uroz M, Kosmalska A, et al. Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores. Cell. 2017;171:1397-1410.e14 pubmed 出版商
Ichikawa T, Kita M, Matsui T, Nagasato A, Araki T, Chiang S, et al. Vinexin family (SORBS) proteins play different roles in stiffness-sensing and contractile force generation. J Cell Sci. 2017;130:3517-3531 pubmed 出版商
Warnke E, Pietsch J, Kopp S, Bauer J, Sahana J, Wehland M, et al. Cytokine Release and Focal Adhesion Proteins in Normal Thyroid Cells Cultured on the Random Positioning Machine. Cell Physiol Biochem. 2017;43:257-270 pubmed 出版商
Sun C, Wacquier B, Aguilar D, Carayol N, Denis K, Boucherie S, et al. The Shigella type III effector IpgD recodes Ca2+ signals during invasion of epithelial cells. EMBO J. 2017;36:2567-2580 pubmed 出版商
Veß A, Blache U, Leitner L, Kurz A, Ehrenpfordt A, Sixt M, et al. A dual phenotype of MDA-MB-468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity. J Cell Sci. 2017;130:2172-2184 pubmed 出版商
Tello Lafoz M, Martínez Martínez G, Rodríguez Rodríguez C, Albar J, Huse M, Gharbi S, et al. Sorting nexin 27 interactome in T-lymphocytes identifies zona occludens-2 dynamic redistribution at the immune synapse. Traffic. 2017;18:491-504 pubmed 出版商
Liskova J, Hadraba D, Filova E, Konarik M, Pirk J, Jelen K, et al. Valve interstitial cell culture: Production of mature type I collagen and precise detection. Microsc Res Tech. 2017;80:936-942 pubmed 出版商
Lim I, Joo H, Jeong M, Kim J, Choi S, Kim C, et al. Talin Modulation by a Synthetic N-Acylurea Derivative Reduces Angiogenesis in Human Endothelial Cells. Int J Mol Sci. 2017;18: pubmed 出版商
Jacquemet G, Baghirov H, Georgiadou M, Sihto H, Peuhu E, Cettour Janet P, et al. L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling. Nat Commun. 2016;7:13297 pubmed 出版商
Alsebaey A, Ahmedy E. Talin-1 and Non-invasive Fibrosis Models in the Assessment of Patients with Hepatocellular Carcinoma. Asian Pac J Cancer Prev. 2016;17:4077-82 pubmed
Hammers D, Sleeper M, Forbes S, Shima A, Walter G, Sweeney H. Tadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin-Deficient Hearts. J Am Heart Assoc. 2016;5: pubmed 出版商
Godinho Santos A, Hance A, Gonçalves J, Mammano F. CIB1 and CIB2 are HIV-1 helper factors involved in viral entry. Sci Rep. 2016;6:30927 pubmed 出版商
Wang X, Li J, Chen S, Shen X, Yang X, Teng Y, et al. Knockdown of HMGN2 increases the internalization of Klebsiella pneumoniae by respiratory epithelial cells through the regulation of α5β1 integrin expression. Int J Mol Med. 2016;38:737-46 pubmed 出版商
Pollizzi K, Sun I, Patel C, Lo Y, Oh M, Waickman A, et al. Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8(+) T cell differentiation. Nat Immunol. 2016;17:704-11 pubmed 出版商
Minns M, Teicher G, Rich C, Trinkaus Randall V. Purinoreceptor P2X7 Regulation of Ca(2+) Mobilization and Cytoskeletal Rearrangement Is Required for Corneal Reepithelialization after Injury. Am J Pathol. 2016;186:285-96 pubmed 出版商
Filova E, Fojt J, Krýslová M, Moravec H, Joska L, Bacakova L. The diameter of nanotubes formed on Ti-6Al-4V alloy controls the adhesion and differentiation of Saos-2 cells. Int J Nanomedicine. 2015;10:7145-63 pubmed 出版商
Austen K, Ringer P, Mehlich A, Chrostek Grashoff A, Kluger C, Klingner C, et al. Extracellular rigidity sensing by talin isoform-specific mechanical linkages. Nat Cell Biol. 2015;17:1597-606 pubmed 出版商
Musílková J, Kotelnikov I, Novotná K, Pop Georgievski O, Rypacek F, Bacakova L, et al. Cell adhesion and growth enabled by biomimetic oligopeptide modification of a polydopamine-poly(ethylene oxide) protein repulsive surface. J Mater Sci Mater Med. 2015;26:253 pubmed 出版商
Lagarrigue F, Vikas Anekal P, Lee H, Bachir A, Ablack J, Horwitz A, et al. A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration. Nat Commun. 2015;6:8492 pubmed 出版商
Yamahashi Y, Cavnar P, Hind L, Berthier E, Bennin D, Beebe D, et al. Integrin associated proteins differentially regulate neutrophil polarity and directed migration in 2D and 3D. Biomed Microdevices. 2015;17:100 pubmed 出版商
Kang W, Kim S, Cho H, Jin J, Lee J, Joo K, et al. Talin1 targeting potentiates anti-angiogenic therapy by attenuating invasion and stem-like features of glioblastoma multiforme. Oncotarget. 2015;6:27239-51 pubmed 出版商
Xu Y, Ren X, Li Y, He Q, Tang X, Sun Y, et al. High expression of Talin-1 is associated with poor prognosis in patients with nasopharyngeal carcinoma. BMC Cancer. 2015;15:332 pubmed 出版商
Bergert M, Erzberger A, Desai R, Aspalter I, Oates A, Charras G, et al. Force transmission during adhesion-independent migration. Nat Cell Biol. 2015;17:524-9 pubmed 出版商
Zhang H, Chen Y, Wadham C, McCaughan G, Keane F, Gorrell M. Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin. Biochim Biophys Acta. 2015;1853:470-80 pubmed 出版商
Kadaré G, Gervasi N, Brami Cherrier K, Blockus H, El Messari S, Arold S, et al. Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells. J Biol Chem. 2015;290:478-91 pubmed 出版商
Rubashkin M, Cassereau L, Bainer R, DuFort C, Yui Y, Ou G, et al. Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. Cancer Res. 2014;74:4597-611 pubmed 出版商
Supinski G, Wang L, Song X, Moylan J, Callahan L. Muscle-specific calpastatin overexpression prevents diaphragm weakness in cecal ligation puncture-induced sepsis. J Appl Physiol (1985). 2014;117:921-9 pubmed 出版商
Ferraris G, Schulte C, Buttiglione V, De Lorenzi V, Piontini A, Galluzzi M, et al. The interaction between uPAR and vitronectin triggers ligand-independent adhesion signalling by integrins. EMBO J. 2014;33:2458-72 pubmed 出版商
Filova E, Suchy T, Sucharda Z, Supová M, Zaloudková M, Balík K, et al. Support for the initial attachment, growth and differentiation of MG-63 cells: a comparison between nano-size hydroxyapatite and micro-size hydroxyapatite in composites. Int J Nanomedicine. 2014;9:3687-706 pubmed 出版商
Jungwirth U, Gojo J, Tuder T, Walko G, Holcmann M, Schöfl T, et al. Calpain-mediated integrin deregulation as a novel mode of action for the anticancer gallium compound KP46. Mol Cancer Ther. 2014;13:2436-49 pubmed 出版商
Rognoni E, Widmaier M, Jakobson M, Ruppert R, Ussar S, Katsougkri D, et al. Kindlin-1 controls Wnt and TGF-? availability to regulate cutaneous stem cell proliferation. Nat Med. 2014;20:350-9 pubmed 出版商
Czarnowski A, Papp S, Száraz P, Opas M. Calreticulin affects cell adhesiveness through differential phosphorylation of insulin receptor substrate-1. Cell Mol Biol Lett. 2014;19:77-97 pubmed 出版商
Baranov M, ter Beest M, Reinieren Beeren I, Cambi A, Figdor C, van den Bogaart G. Podosomes of dendritic cells facilitate antigen sampling. J Cell Sci. 2014;127:1052-1064 pubmed 出版商
Joshi R, Schmidt A, Das J, Pytel D, Riese M, Lester M, et al. The ? isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling. Sci Signal. 2013;6:ra102 pubmed 出版商
Shen B, Zhao X, O Brien K, Stojanovic Terpo A, Delaney M, Kim K, et al. A directional switch of integrin signalling and a new anti-thrombotic strategy. Nature. 2013;503:131-5 pubmed 出版商
Willenbrock F, Zicha D, Hoppe A, Hogg N. Novel automated tracking analysis of particles subjected to shear flow: kindlin-3 role in B cells. Biophys J. 2013;105:1110-22 pubmed 出版商
Teräväinen T, Myllymäki S, Friedrichs J, Strohmeyer N, Moyano J, Wu C, et al. ?V-integrins are required for mechanotransduction in MDCK epithelial cells. PLoS ONE. 2013;8:e71485 pubmed 出版商
Sáez de Guinoa J, Barrio L, Carrasco Y. Vinculin arrests motile B cells by stabilizing integrin clustering at the immune synapse. J Immunol. 2013;191:2742-51 pubmed 出版商
Kostourou V, Lechertier T, Reynolds L, Lees D, Baker M, Jones D, et al. FAK-heterozygous mice display enhanced tumour angiogenesis. Nat Commun. 2013;4:2020 pubmed 出版商
Chiang Y, Ho K, Sun C, Chiu J, Lee F, Liao F, et al. CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration. PLoS ONE. 2013;8:e61761 pubmed 出版商
Roca Cusachs P, Del Rio A, Puklin Faucher E, Gauthier N, Biais N, Sheetz M. Integrin-dependent force transmission to the extracellular matrix by ?-actinin triggers adhesion maturation. Proc Natl Acad Sci U S A. 2013;110:E1361-70 pubmed 出版商
Tong L, Png E, Aihua H, Yong S, Yeo H, Riau A, et al. Molecular mechanism of transglutaminase-2 in corneal epithelial migration and adhesion. Biochim Biophys Acta. 2013;1833:1304-15 pubmed 出版商
Ham H, Guerrier S, Kim J, Schoon R, Anderson E, Hamann M, et al. Dedicator of cytokinesis 8 interacts with talin and Wiskott-Aldrich syndrome protein to regulate NK cell cytotoxicity. J Immunol. 2013;190:3661-9 pubmed 出版商
Shin J, Krey J, Hassan A, Metlagel Z, Tauscher A, Pagana J, et al. Molecular architecture of the chick vestibular hair bundle. Nat Neurosci. 2013;16:365-74 pubmed 出版商
Brody M, Hacker T, Patel J, Feng L, Sadoshima J, Tevosian S, et al. Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy. PLoS ONE. 2012;7:e51621 pubmed 出版商
Gawecka J, Young Robbins S, Sulzmaier F, Caliva M, Heikkila M, Matter M, et al. RSK2 protein suppresses integrin activation and fibronectin matrix assembly and promotes cell migration. J Biol Chem. 2012;287:43424-37 pubmed 出版商
Kato H, Liao Z, Mitsios J, Wang H, Deryugina E, Varner J, et al. The primacy of β1 integrin activation in the metastatic cascade. PLoS ONE. 2012;7:e46576 pubmed 出版商
Menon A, Eddinger T, Wang H, Wendell D, Toth J, LaDisa J. Altered hemodynamics, endothelial function, and protein expression occur with aortic coarctation and persist after repair. Am J Physiol Heart Circ Physiol. 2012;303:H1304-18 pubmed 出版商
Beaumont K, Mrksich M. The mechanostability of isolated focal adhesions is strongly dependent on pH. Chem Biol. 2012;19:711-20 pubmed 出版商
Zhang F, Saha S, Kashina A. Arginylation-dependent regulation of a proteolytic product of talin is essential for cell-cell adhesion. J Cell Biol. 2012;197:819-36 pubmed 出版商
Parizek M, Douglas T, Novotná K, Kromka A, Brady M, Renzing A, et al. Nanofibrous poly(lactide-co-glycolide) membranes loaded with diamond nanoparticles as promising substrates for bone tissue engineering. Int J Nanomedicine. 2012;7:1931-51 pubmed 出版商
Sequeira S, Soscia D, Oztan B, Mosier A, Jean Gilles R, Gadre A, et al. The regulation of focal adhesion complex formation and salivary gland epithelial cell organization by nanofibrous PLGA scaffolds. Biomaterials. 2012;33:3175-86 pubmed 出版商
Daley W, Kohn J, Larsen M. A focal adhesion protein-based mechanochemical checkpoint regulates cleft progression during branching morphogenesis. Dev Dyn. 2011;240:2069-83 pubmed 出版商
Li G, Du X, Vass W, Papageorge A, Lowy D, Qian X. Full activity of the deleted in liver cancer 1 (DLC1) tumor suppressor depends on an LD-like motif that binds talin and focal adhesion kinase (FAK). Proc Natl Acad Sci U S A. 2011;108:17129-34 pubmed 出版商
Tzircotis G, Braga V, Caron E. RhoG is required for both FcγR- and CR3-mediated phagocytosis. J Cell Sci. 2011;124:2897-902 pubmed 出版商
Brunner M, Millon Fremillon A, Chevalier G, Nakchbandi I, Mosher D, Block M, et al. Osteoblast mineralization requires beta1 integrin/ICAP-1-dependent fibronectin deposition. J Cell Biol. 2011;194:307-22 pubmed 出版商
Grausova L, Kromka A, Burdikova Z, Eckhardt A, Rezek B, Vacik J, et al. Enhanced growth and osteogenic differentiation of human osteoblast-like cells on boron-doped nanocrystalline diamond thin films. PLoS ONE. 2011;6:e20943 pubmed 出版商
Lai M, Hua C, Tsai M, Wan L, Lin Y, Chen C, et al. Talin-1 overexpression defines high risk for aggressive oral squamous cell carcinoma and promotes cancer metastasis. J Pathol. 2011;224:367-76 pubmed 出版商
Tsun A, Qureshi I, Stinchcombe J, Jenkins M, de la Roche M, Kleczkowska J, et al. Centrosome docking at the immunological synapse is controlled by Lck signaling. J Cell Biol. 2011;192:663-74 pubmed 出版商
Zhu H, Riau A, Beuerman R. Epithelial microfilament regulators show regional distribution in mouse conjunctiva. Mol Vis. 2010;16:2215-24 pubmed
Wyss H, Henderson J, Byfield F, Bruggeman L, Ding Y, Huang C, et al. Biophysical properties of normal and diseased renal glomeruli. Am J Physiol Cell Physiol. 2011;300:C397-405 pubmed 出版商
Xu Y, Bismar T, Su J, Xu B, Kristiansen G, Varga Z, et al. Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion. J Exp Med. 2010;207:2421-37 pubmed 出版商
Selsby J, Pendrak K, Zadel M, Tian Z, Pham J, Carver T, et al. Leupeptin-based inhibitors do not improve the mdx phenotype. Am J Physiol Regul Integr Comp Physiol. 2010;299:R1192-201 pubmed 出版商
Zhang G, Thomas A, Marshall A, Kernan K, Su Y, Zheng Y, et al. Nicotinic acetylcholine receptor ?1 promotes calpain-1 activation and macrophage inflammation in hypercholesterolemic nephropathy. Lab Invest. 2011;91:106-23 pubmed 出版商
Bordeleau F, Galarneau L, Gilbert S, Loranger A, Marceau N. Keratin 8/18 modulation of protein kinase C-mediated integrin-dependent adhesion and migration of liver epithelial cells. Mol Biol Cell. 2010;21:1698-713 pubmed 出版商
Millan J, Cain R, Reglero Real N, Bigarella C, Marcos Ramiro B, Fernández Martín L, et al. Adherens junctions connect stress fibres between adjacent endothelial cells. BMC Biol. 2010;8:11 pubmed 出版商
Parizek M, Kasalkova N, Bacakova L, Slepicka P, Lisa V, Blazkova M, et al. Improved adhesion, growth and maturation of vascular smooth muscle cells on polyethylene grafted with bioactive molecules and carbon particles. Int J Mol Sci. 2009;10:4352-74 pubmed 出版商
Saltel F, Mortier E, Hytönen V, Jacquier M, Zimmermann P, Vogel V, et al. New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering. J Cell Biol. 2009;187:715-31 pubmed 出版商
Renkawitz J, Schumann K, Weber M, Lämmermann T, Pflicke H, Piel M, et al. Adaptive force transmission in amoeboid cell migration. Nat Cell Biol. 2009;11:1438-43 pubmed 出版商
Manevich Mendelson E, Feigelson S, Pasvolsky R, Aker M, Grabovsky V, Shulman Z, et al. Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions. Blood. 2009;114:2344-53 pubmed 出版商
Erikson D, Burghardt R, Bayless K, Johnson G. Secreted phosphoprotein 1 (SPP1, osteopontin) binds to integrin alpha v beta 6 on porcine trophectoderm cells and integrin alpha v beta 3 on uterine luminal epithelial cells, and promotes trophectoderm cell adhesion and migration. Biol Reprod. 2009;81:814-25 pubmed 出版商
Burghardt R, Burghardt J, Taylor J, Reeder A, Nguen B, Spencer T, et al. Enhanced focal adhesion assembly reflects increased mechanosensation and mechanotransduction at maternal-conceptus interface and uterine wall during ovine pregnancy. Reproduction. 2009;137:567-82 pubmed 出版商
Thompson O, Kleino I, Crimaldi L, Gimona M, Saksela K, Winder S. Dystroglycan, Tks5 and Src mediated assembly of podosomes in myoblasts. PLoS ONE. 2008;3:e3638 pubmed 出版商
Evans M, Morine K, Kulkarni C, Barton E. Expression profiling reveals heightened apoptosis and supports fiber size economy in the murine muscles of mastication. Physiol Genomics. 2008;35:86-95 pubmed 出版商
Lieber S, Qiu H, Chen L, Shen Y, Hong C, Hunter W, et al. Cardiac dysfunction in aging conscious rats: altered cardiac cytoskeletal proteins as a potential mechanism. Am J Physiol Heart Circ Physiol. 2008;295:H860-6 pubmed 出版商
Banz Y, Beldi G, Wu Y, Atkinson B, Usheva A, Robson S. CD39 is incorporated into plasma microparticles where it maintains functional properties and impacts endothelial activation. Br J Haematol. 2008;142:627-37 pubmed 出版商
Hao J, Wang G, Pisitkun T, Patino Lopez G, Nagashima K, Knepper M, et al. Enrichment of distinct microfilament-associated and GTP-binding-proteins in membrane/microvilli fractions from lymphoid cells. J Proteome Res. 2008;7:2911-27 pubmed 出版商
Cortesio C, Chan K, Perrin B, Burton N, Zhang S, Zhang Z, et al. Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion. J Cell Biol. 2008;180:957-71 pubmed 出版商
Millon Fremillon A, Bouvard D, Grichine A, Manet Dupé S, Block M, Albiges Rizo C. Cell adaptive response to extracellular matrix density is controlled by ICAP-1-dependent beta1-integrin affinity. J Cell Biol. 2008;180:427-41 pubmed 出版商
Petrich B, Marchese P, Ruggeri Z, Spiess S, Weichert R, Ye F, et al. Talin is required for integrin-mediated platelet function in hemostasis and thrombosis. J Exp Med. 2007;204:3103-11 pubmed
Humphries J, Wang P, Streuli C, Geiger B, Humphries M, Ballestrem C. Vinculin controls focal adhesion formation by direct interactions with talin and actin. J Cell Biol. 2007;179:1043-57 pubmed
Morita T, Mayanagi T, Sobue K. Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling. J Cell Biol. 2007;179:1027-42 pubmed
Glading A, Han J, Stockton R, Ginsberg M. KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions. J Cell Biol. 2007;179:247-54 pubmed
Mellgren R, Huang X. Fetuin A stabilizes m-calpain and facilitates plasma membrane repair. J Biol Chem. 2007;282:35868-77 pubmed
Farmer J, Burghardt R, Jousan F, Hansen P, Bazer F, Spencer T. Galectin 15 (LGALS15) functions in trophectoderm migration and attachment. FASEB J. 2008;22:548-60 pubmed 出版商
Mavlyutov T, Ruoho A. Ligand-dependent localization and intracellular stability of sigma-1 receptors in CHO-K1 cells. J Mol Signal. 2007;2:8 pubmed
Prager G, Feral C, Kim C, Han J, Ginsberg M. CD98hc (SLC3A2) interaction with the integrin beta subunit cytoplasmic domain mediates adhesive signaling. J Biol Chem. 2007;282:24477-84 pubmed
Sims T, Soos T, Xenias H, Dubin Thaler B, Hofman J, Waite J, et al. Opposing effects of PKCtheta and WASp on symmetry breaking and relocation of the immunological synapse. Cell. 2007;129:773-85 pubmed
Seng S, Avraham H, Jiang S, Venkatesh S, Avraham S. KLHL1/MRP2 mediates neurite outgrowth in a glycogen synthase kinase 3beta-dependent manner. Mol Cell Biol. 2006;26:8371-84 pubmed
Bairstow S, Ling K, Su X, Firestone A, Carbonara C, Anderson R. Type Igamma661 phosphatidylinositol phosphate kinase directly interacts with AP2 and regulates endocytosis. J Biol Chem. 2006;281:20632-42 pubmed
Windoffer R, Kölsch A, Wöll S, Leube R. Focal adhesions are hotspots for keratin filament precursor formation. J Cell Biol. 2006;173:341-8 pubmed
Yuan W, Leisner T, McFadden A, Wang Z, Larson M, Clark S, et al. CIB1 is an endogenous inhibitor of agonist-induced integrin alphaIIbbeta3 activation. J Cell Biol. 2006;172:169-75 pubmed
Smith A, Carrasco Y, Stanley P, Kieffer N, Batista F, Hogg N. A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes. J Cell Biol. 2005;170:141-51 pubmed
Powner D, Payne R, Pettitt T, Giudici M, Irvine R, Wakelam M. Phospholipase D2 stimulates integrin-mediated adhesion via phosphatidylinositol 4-phosphate 5-kinase Igamma b. J Cell Sci. 2005;118:2975-86 pubmed
Proux Gillardeaux V, Gavard J, Irinopoulou T, Mège R, Galli T. Tetanus neurotoxin-mediated cleavage of cellubrevin impairs epithelial cell migration and integrin-dependent cell adhesion. Proc Natl Acad Sci U S A. 2005;102:6362-7 pubmed
Clement S, Hinz B, Dugina V, Gabbiani G, Chaponnier C. The N-terminal Ac-EEED sequence plays a role in alpha-smooth-muscle actin incorporation into stress fibers. J Cell Sci. 2005;118:1395-404 pubmed
Critchley D. Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion. Biochem Soc Trans. 2004;32:831-6 pubmed
Le Boeuf F, Houle F, Huot J. Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities. J Biol Chem. 2004;279:39175-85 pubmed
Nelson C, Pirone D, Tan J, Chen C. Vascular endothelial-cadherin regulates cytoskeletal tension, cell spreading, and focal adhesions by stimulating RhoA. Mol Biol Cell. 2004;15:2943-53 pubmed
Jolly C, Kashefi K, Hollinshead M, Sattentau Q. HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse. J Exp Med. 2004;199:283-93 pubmed
Somersalo K, Anikeeva N, Sims T, Thomas V, Strong R, Spies T, et al. Cytotoxic T lymphocytes form an antigen-independent ring junction. J Clin Invest. 2004;113:49-57 pubmed
Garvalov B, Higgins T, Sutherland J, Zettl M, Scaplehorn N, Kocher T, et al. The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions. J Cell Biol. 2003;161:33-9 pubmed
van der Flier A, Kuikman I, Kramer D, Geerts D, Kreft M, Takafuta T, et al. Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits. J Cell Biol. 2002;156:361-76 pubmed
D Addario M, Arora P, Fan J, Ganss B, Ellen R, McCulloch C. Cytoprotection against mechanical forces delivered through beta 1 integrins requires induction of filamin A. J Biol Chem. 2001;276:31969-77 pubmed
Parast M, Aeder S, Sutherland A. Trophoblast giant-cell differentiation involves changes in cytoskeleton and cell motility. Dev Biol. 2001;230:43-60 pubmed
Klingbeil C, Hauck C, Hsia D, Jones K, Reider S, Schlaepfer D. Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cells. J Cell Biol. 2001;152:97-110 pubmed
Penas P, Garcia Diez A, Sanchez Madrid F, Yanez Mo M. Tetraspanins are localized at motility-related structures and involved in normal human keratinocyte wound healing migration. J Invest Dermatol. 2000;114:1126-35 pubmed
Elliott D, Clark D. Cryptosporidium parvum induces host cell actin accumulation at the host-parasite interface. Infect Immun. 2000;68:2315-22 pubmed
Allen L, Schlesinger L, Kang B. Virulent strains of Helicobacter pylori demonstrate delayed phagocytosis and stimulate homotypic phagosome fusion in macrophages. J Exp Med. 2000;191:115-28 pubmed
Giron J, Lange M, Baseman J. Adherence, fibronectin binding, and induction of cytoskeleton reorganization in cultured human cells by Mycoplasma penetrans. Infect Immun. 1996;64:197-208 pubmed
Glukhova M, Koteliansky V, Sastre X, Thiery J. Adhesion systems in normal breast and in invasive breast carcinoma. Am J Pathol. 1995;146:706-16 pubmed
产品信息
Product No. :
T3287
产品名称 :
单克隆抗踝蛋白在小鼠生产的抗体
宿主 :
小鼠
共轭标签 :
未共轭
抗体类型 :
单克隆
Clone Number (if monoclonal) :
8d4
应用/描述 :
Suitable for immunoprecipitation (IP); western blot: 1:100 using chicken gizzard extract; indirect immunofluorescence: 1:500 using cultured Rat2 cells
物种活性 :
frog, mouse, rat, human, chicken
抗体亚型 :
IgG1
储存 :
存放在-20°C
更多信息或购买 :
公司信息
西格玛奥德里奇
上海市徐汇区淮海中路1010号嘉华中心41楼
techservCN@sial.com
http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
公司总部: 美国
Sigma-Aldrich是一家在生命科学领域领先的且拥有高科技产品的公司,致力于为生命科学、制药化工等领域提供高质量的服务和产品。