产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
产品类型 :
抗体
产品名称 :
Monoclonal Anti-α-Tubulin antibody produced in mouse
目录 :
T5168
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
B-5-1-2
反应物种 :
酵母菌目, fission yeast, 仓鼠, 中国人仓鼠, 人类, 小鼠, 大鼠, , , , 斑马鱼, fruit fly , 家羊, 非洲爪蛙, 拟南芥, 大豆, 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 放射免疫分析法, 免疫组化-石蜡切片, 免疫组化-冰冻切片, reverse phase protein lysate microarray
更多信息或购买 :
文章摘录数: 2624
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:10,000; 图 5a
Vega M, Finlay J, Vasishtha M, Schwarzbauer J. Elevated glucose alters global gene expression and tenascin-C alternative splicing in mesangial cells. Matrix Biol Plus. 2020;8:100048 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 5a
Fucíková J, Kepp O, Kasikova L, Petroni G, Yamazaki T, Liu P, et al. Detection of immunogenic cell death and its relevance for cancer therapy. Cell Death Dis. 2020;11:1013 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 5a
Barrett L, Chen J, Dai L, Plaisance Bonstaff K, Del Valle L, Qin Z. Role of Interleukin-1 Family Members and Signaling Pathways in KSHV Pathogenesis. Front Cell Infect Microbiol. 2020;10:587929 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 5b
Hao Q, Zong X, Sun Q, Lin Y, Song Y, Hashemikhabir S, et al. The S-phase-induced lncRNA SUNO1 promotes cell proliferation by controlling YAP1/Hippo signaling pathway. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 5a
Meini S, Zanichelli A, Sbrojavacca R, Iuri F, Roberts A, Suffritti C, et al. Understanding the Pathophysiology of COVID-19: Could the Contact System Be the Key?. Front Immunol. 2020;11:2014 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3a
Capaci V, Bascetta L, Fantuz M, Beznoussenko G, Sommaggio R, Cancila V, et al. Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome. Nat Commun. 2020;11:3945 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 5a
James N, Woodman M, DiSilvestro P, Ribeiro J. The Perfect Combination: Enhancing Patient Response to PD-1-Based Therapies in Epithelial Ovarian Cancer. Cancers (Basel). 2020;12: pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 5a
Li L, Xue W, Shen Z, Liu J, Hu M, Cheng Z, et al. A Cereblon Modulator CC-885 Induces CRBN- and p97-Dependent PLK1 Degradation and Synergizes with Volasertib to Suppress Lung Cancer. Mol Ther Oncolytics. 2020;18:215-225 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 5a
van der Weyden L, Brenn T, Patton E, Wood G, Adams D. Spontaneously occurring melanoma in animals and their relevance to human melanoma. J Pathol. 2020;252:4-21 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 5a
Avagliano A, Fiume G, Ruocco M, Martucci N, Vecchio E, Insabato L, et al. Influence of Fibroblasts on Mammary Gland Development, Breast Cancer Microenvironment Remodeling, and Cancer Cell Dissemination. Cancers (Basel). 2020;12: pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 2f
Lechertier T, Reynolds L, Kim H, Pedrosa A, Gómez Escudero J, Muñoz Félix J, et al. Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth. Nat Commun. 2020;11:2810 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 5a
Sapaly D, Delers P, Coridon J, Salman B, Letourneur F, Dumont F, et al. The Small-Molecule Flunarizine in Spinal Muscular Atrophy Patient Fibroblasts Impacts on the Gemin Components of the SMN Complex and TDP43, an RNA-Binding Protein Relevant to Motor Neuron Diseases. Front Mol Biosci. 2020;7:55 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1b
Bozic M, Caus M, Rodrigues Díez R, Pedraza N, Ruiz Ortega M, Garí E, et al. Protective role of renal proximal tubular alpha-synuclein in the pathogenesis of kidney fibrosis. Nat Commun. 2020;11:1943 pubmed 出版商
  • 免疫组化; 大鼠; 1:1000; 图 4a
Gallo S, Spilinga M, Albano R, Ferrauto G, Di Gregorio E, Casanova E, et al. Activation of the MET receptor attenuates doxorubicin-induced cardiotoxicity in vivo and in vitro. Br J Pharmacol. 2020;177:3107-3122 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Leite M, Marques M, Melo J, Pinto M, Cavadas B, Aroso M, et al. Helicobacter Pylori Targets the EPHA2 Receptor Tyrosine Kinase in Gastric Cells Modulating Key Cellular Functions. Cells. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 5g
Sciascia N, Wu W, Zong D, Sun Y, Wong N, John S, et al. Suppressing proteasome mediated processing of Topoisomerase II DNA-protein complexes preserves genome integrity. elife. 2020;9: pubmed 出版商
  • 免疫组化; 小鼠; 1:5000; 图 4f
Zhao L, Ke H, Xu H, Wang G, Zhang H, Zou L, et al. TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh. Nat Commun. 2020;11:341 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4b
Naiman S, Huynh F, Gil R, Glick Y, Shahar Y, Touitou N, et al. SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα. Cell Rep. 2019;29:4127-4143.e8 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 1b
Nakamura Y, Dryanovski D, Kimura Y, Jackson S, Woods A, Yasui Y, et al. Cocaine-induced endocannabinoid signaling mediated by sigma-1 receptors and extracellular vesicle secretion. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6c
Arrondel C, Missoury S, Snoek R, Patat J, Menara G, Collinet B, et al. Defects in t6A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome. Nat Commun. 2019;10:3967 pubmed 出版商
  • 免疫印迹; 人类; 图 3f
Sanghvi V, Leibold J, Mina M, Mohan P, Berishaj M, Li Z, et al. The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase. Cell. 2019;178:807-819.e21 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1d
Ommer A, Figlia G, Pereira J, Datwyler A, Gerber J, Degeer J, et al. Ral GTPases in Schwann cells promote radial axonal sorting in the peripheral nervous system. J Cell Biol. 2019;: pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1b
Sauer M, Juranek S, Marks J, De Magis A, Kazemier H, Hilbig D, et al. DHX36 prevents the accumulation of translationally inactive mRNAs with G4-structures in untranslated regions. Nat Commun. 2019;10:2421 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 6b
Mikuličić S, Finke J, Boukhallouk F, Wüstenhagen E, Sons D, Homsi Y, et al. ADAM17-dependent signaling is required for oncogenic human papillomavirus entry platform assembly. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 图 7d
Gregersen L, Mitter R, Ugalde A, Nojima T, Proudfoot N, Agami R, et al. SCAF4 and SCAF8, mRNA Anti-Terminator Proteins. Cell. 2019;: pubmed 出版商
  • 免疫印迹; fruit fly ; 图 1s1b
Weiss S, Melom J, Ormerod K, Zhang Y, Littleton J. Glial Ca2+signaling links endocytosis to K+ buffering around neuronal somas to regulate excitability. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 6d
Wu W, Zhang W, Choi M, Zhao J, Gao P, Xue M, et al. Vascular smooth muscle-MAPK14 is required for neointimal hyperplasia by suppressing VSMC differentiation and inducing proliferation and inflammation. Redox Biol. 2019;22:101137 pubmed 出版商
  • 免疫印迹; 人类; 图 6b
Kubli S, Bassi C, Roux C, Wakeham A, Göbl C, Zhou W, et al. AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer. Proc Natl Acad Sci U S A. 2019;116:3604-3613 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Paul D, Islam S, Manne R, Dinesh U, Malonia S, Maity B, et al. F-box protein FBXO16 functions as a tumor suppressor by attenuating nuclear β-catenin function. J Pathol. 2019;248:266-279 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 7a
  • 免疫印迹; 人类; 1:2000; 图 5b
Song K, Gras C, Capin G, Gimber N, Lehmann M, Mohd S, et al. A SEPT1-based scaffold is required for Golgi integrity and function. J Cell Sci. 2019;132: pubmed 出版商
  • 免疫印迹; 小鼠; 图 2d
Guo J, Dai X, Laurent B, Zheng N, Gan W, Zhang J, et al. AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions. Nat Cell Biol. 2019;21:226-237 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 4e
Fenderico N, van Scherpenzeel R, Goldflam M, Proverbio D, Jordens I, Kralj T, et al. Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells. Nat Commun. 2019;10:365 pubmed 出版商
  • 免疫印迹; 人类; 图 3d
Vítor A, Sridhara S, Sabino J, Afonso A, Grosso A, Martin R, et al. Single-molecule imaging of transcription at damaged chromatin. Sci Adv. 2019;5:eaau1249 pubmed 出版商
  • 免疫印迹; 人类; 图 8a
Li Z, Mbah N, Overmeyer J, Sarver J, George S, Trabbic C, et al. The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma. BMC Cancer. 2019;19:77 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 5i
Wintgens J, Wichert S, Popovic L, Rossner M, Wehr M. Monitoring activities of receptor tyrosine kinases using a universal adapter in genetically encoded split TEV assays. Cell Mol Life Sci. 2019;76:1185-1199 pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 s2d
Silberman A, Goldman O, Boukobza Assayag O, Jacob A, Rabinovich S, Adler L, et al. Acid-Induced Downregulation of ASS1 Contributes to the Maintenance of Intracellular pH in Cancer. Cancer Res. 2019;79:518-533 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s4b
  • 免疫印迹; 人类; 图 3c
Zhang Y, Tan L, Yang Q, Li C, Liou Y. The microtubule-associated protein HURP recruits the centrosomal protein TACC3 to regulate K-fiber formation and support chromosome congression. J Biol Chem. 2018;293:15733-15747 pubmed 出版商
  • 免疫印迹; 人类; 图 4b
Kühnl A, Musiol A, Heitzig N, Johnson D, Ehrhardt C, Grewal T, et al. Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus. MBio. 2018;9: pubmed 出版商
  • 免疫组化-冰冻切片; 拟南芥; 1:100; 图 6c
Reipert S, Goldammer H, Richardson C, Goldberg M, Hawkins T, Hollergschwandtner E, et al. Agitation Modules: Flexible Means to Accelerate Automated Freeze Substitution. J Histochem Cytochem. 2018;66:903-921 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Bernal A, Moltó Abad M, Dominguez D, Tusell L. Acute telomere deprotection prevents ongoing BFB cycles and rampant instability in p16INK4a-deficient epithelial cells. Oncotarget. 2018;9:27151-27170 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4f
Ribeiro de Almeida C, Dhir S, Dhir A, Moghaddam A, Sattentau Q, Meinhart A, et al. RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination. Mol Cell. 2018;70:650-662.e8 pubmed 出版商
  • 免疫细胞化学; 人类; 1:5000; 图 1g
Bhardwaj A, Yang Y, Ueberheide B, Smith S. Whole proteome analysis of human tankyrase knockout cells reveals targets of tankyrase-mediated degradation. Nat Commun. 2017;8:2214 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4b
  • 免疫印迹; 人类; 图 4a
Stevenson N, Bergen D, Skinner R, Kague E, Martin Silverstone E, Robson Brown K, et al. Giantin-knockout models reveal a feedback loop between Golgi function and glycosyltransferase expression. J Cell Sci. 2017;130:4132-4143 pubmed 出版商
  • 免疫印迹; 人类; 图 8
Bartusch C, Döring T, Prange R. Rab33B Controls Hepatitis B Virus Assembly by Regulating Core Membrane Association and Nucleocapsid Processing. Viruses. 2017;9: pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 s5g
Moradi M, Sivadasan R, Saal L, Lüningschrör P, Dombert B, Rathod R, et al. Differential roles of α-, β-, and γ-actin in axon growth and collateral branch formation in motoneurons. J Cell Biol. 2017;216:793-814 pubmed 出版商
  • 免疫细胞化学; 鸡; 图 10b
Boswell B, Korol A, West Mays J, Musil L. Dual function of TGF? in lens epithelial cell fate: implications for secondary cataract. Mol Biol Cell. 2017;28:907-921 pubmed 出版商
  • 免疫印迹; fruit fly ; 图 1e
Vonk J, Yeshaw W, Pinto F, Faber A, Lahaye L, Kanon B, et al. Drosophila Vps13 Is Required for Protein Homeostasis in the Brain. PLoS ONE. 2017;12:e0170106 pubmed 出版商
  • 免疫印迹; 人类; 图 2
  • 免疫印迹; 小鼠; 图 6
Cizmecioglu O, Ni J, Xie S, Zhao J, Roberts T. Rac1-mediated membrane raft localization of PI3K/p110? is required for its activation by GPCRs or PTEN loss. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 中国人仓鼠; 1:5000; 图 1
  • 免疫印迹; 人类; 1:5000; 图 2
Qi L, Jafari N, Li X, Chen Z, Li L, Hytönen V, et al. Talin2-mediated traction force drives matrix degradation and cell invasion. J Cell Sci. 2016;129:3661-3674 pubmed
  • 免疫印迹; 小鼠; 1:5000; 图 4
Hu H, Umemori H, Hsueh Y. Postsynaptic SDC2 induces transsynaptic signaling via FGF22 for bidirectional synaptic formation. Sci Rep. 2016;6:33592 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Zhu S, Henninger K, McGrath B, Cavener D. PERK Regulates Working Memory and Protein Synthesis-Dependent Memory Flexibility. PLoS ONE. 2016;11:e0162766 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1
Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Agatheeswaran S, Pattnayak N, Chakraborty S. Identification and functional characterization of the miRNA-gene regulatory network in chronic myeloid leukemia lineage negative cells. Sci Rep. 2016;6:32493 pubmed 出版商
  • 免疫印迹; fission yeast; 1:5000; 图 9
Rijal K, Maraia R. Active Center Control of Termination by RNA Polymerase III and tRNA Gene Transcription Levels In Vivo. PLoS Genet. 2016;12:e1006253 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7b
Ramo K, Sugamura K, Craige S, Keaney J, Davis R. Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 3
Lie E, Ko J, Choi S, Roh J, Cho Y, Noh R, et al. SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion. Nat Commun. 2016;7:12328 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 2
Di Siena S, Gimmelli R, Nori S, Barbagallo F, Campolo F, Dolci S, et al. Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury. Cell Death Dis. 2016;7:e2317 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Cao J, Wu L, Zhang S, Lu M, Cheung W, Cai W, et al. An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting. Nucleic Acids Res. 2016;44:e149 pubmed
  • 免疫印迹; 人类; 1:10,000; 图 5
Kurg R, Reinsalu O, Jagur S, Ounap K, Võsa L, Kasvandik S, et al. Biochemical and proteomic characterization of retrovirus Gag based microparticles carrying melanoma antigens. Sci Rep. 2016;6:29425 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
  • 免疫印迹; 人类; 1:200; 图 s8
Yang C, Suzuki M, Yamakawa S, Uno S, Ishii A, Yamazaki S, et al. Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells. Nat Commun. 2016;7:12135 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:2000; 图 10
  • 免疫印迹; 小鼠; 1:4000; 图 13
Schmitt D, Funk N, Blum R, Asan E, Andersen L, Rülicke T, et al. Initial characterization of a Syap1 knock-out mouse and distribution of Syap1 in mouse brain and cultured motoneurons. Histochem Cell Biol. 2016;146:489-512 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Marquer C, Tian H, Yi J, Bastien J, Dall Armi C, Yang Klingler Y, et al. Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism. Nat Commun. 2016;7:11919 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Toft D, Fuller M, Schipma M, Chen F, Cryns V, Layden B. ?B-crystallin and HspB2 deficiency is protective from diet-induced glucose intolerance. Genom Data. 2016;9:10-7 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:5000; 图 5a
Dai J, Lu Y, Wang C, Chen X, Fan X, Gu H, et al. Vps33b regulates Vwf-positive vesicular trafficking in megakaryocytes. J Pathol. 2016;240:108-19 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
  • 免疫印迹; 人类; 图 2
Skoge R, Ziegler M. SIRT2 inactivation reveals a subset of hyperacetylated perinuclear microtubules inaccessible to HDAC6. J Cell Sci. 2016;129:2972-82 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1
Qi Y, Yu J, Han W, Fan X, Qian H, Wei H, et al. A splicing isoform of TEAD4 attenuates the Hippo-YAP signalling to inhibit tumour proliferation. Nat Commun. 2016;7:ncomms11840 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s4
  • 免疫印迹; 人类; 图 2
Brunk K, Zhu M, Bärenz F, Kratz A, Haselmann Weiss U, Antony C, et al. Cep78 is a new centriolar protein involved in Plk4-induced centriole overduplication. J Cell Sci. 2016;129:2713-8 pubmed 出版商
  • 免疫印迹; fission yeast; 图 5
Ma N, Ma Y, Nakashima A, Kikkawa U, Furuyashiki T. The Loss of Lam2 and Npr2-Npr3 Diminishes the Vacuolar Localization of Gtr1-Gtr2 and Disinhibits TORC1 Activity in Fission Yeast. PLoS ONE. 2016;11:e0156239 pubmed 出版商
  • 免疫印迹; 人类; 1:4000; 图 4
Lopez A, Kugelman J, Garcia Rivera J, Urias E, Salinas S, Fernandez Zapico M, et al. The Structure-Specific Recognition Protein 1 Associates with Lens Epithelium-Derived Growth Factor Proteins and Modulates HIV-1 Replication. J Mol Biol. 2016;428:2814-31 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Franks T, Benner C, Narvaiza I, Marchetto M, Young J, Malik H, et al. Evolution of a transcriptional regulator from a transmembrane nucleoporin. Genes Dev. 2016;30:1155-71 pubmed 出版商
  • 免疫印迹; 大鼠; 1:10,000; 图 3
  • 免疫印迹; 小鼠; 1:10,000; 图 s7
Fusté N, Fernández Hernández R, Cemeli T, Mirantes C, Pedraza N, Rafel M, et al. Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin. Nat Commun. 2016;7:11581 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Lock R, Ingraham R, Maertens O, Miller A, Weledji N, Legius E, et al. Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers. J Clin Invest. 2016;126:2181-90 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Wang L, Lee K, Malonis R, SANCHEZ I, Dynlacht B. Tethering of an E3 ligase by PCM1 regulates the abundance of centrosomal KIAA0586/Talpid3 and promotes ciliogenesis. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 图 7
Maria O, Liu Y, El Hakim M, Zeitouni A, Tran S. The role of human fibronectin- or placenta basement membrane extract-based gels in favouring the formation of polarized salivary acinar-like structures. J Tissue Eng Regen Med. 2017;11:2643-2657 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Ahrabi S, Sarkar S, Pfister S, Pirovano G, Higgins G, Porter A, et al. A role for human homologous recombination factors in suppressing microhomology-mediated end joining. Nucleic Acids Res. 2016;44:5743-57 pubmed 出版商
  • 免疫印迹; 小鼠; 1:25,000; 图 1
Rodriguez Ortiz C, Flores J, Valenzuela J, Rodriguez G, Zumkehr J, Tran D, et al. The Myoblast C2C12 Transfected with Mutant Valosin-Containing Protein Exhibits Delayed Stress Granule Resolution on Oxidative Stress. Am J Pathol. 2016;186:1623-34 pubmed 出版商
  • 免疫印迹; fruit fly ; 1:10,000; 图 1
Kwenda L, Collins C, Dattoli A, Dunleavy E. Nucleolar activity and CENP-C regulate CENP-A and CAL1 availability for centromere assembly in meiosis. Development. 2016;143:1400-12 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Chaudhary S, Madhukrishna B, Adhya A, Keshari S, Mishra S. Overexpression of caspase 7 is ER? dependent to affect proliferation and cell growth in breast cancer cells by targeting p21(Cip). Oncogenesis. 2016;5:e219 pubmed 出版商
  • 免疫印迹; 非洲爪蛙; 图 2
Chu C, Ossipova O, Ioannou A, Sokol S. Prickle3 synergizes with Wtip to regulate basal body organization and cilia growth. Sci Rep. 2016;6:24104 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5
Canton J, Schlam D, Breuer C, Gutschow M, Glogauer M, Grinstein S. Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages. Nat Commun. 2016;7:11284 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 7
Yadav P, Selvaraj B, Bender F, Behringer M, Moradi M, Sivadasan R, et al. Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Acta Neuropathol. 2016;132:93-110 pubmed 出版商
  • 免疫细胞化学; 人类; 1:3000; 图 5
  • 免疫印迹; 人类; 1:3000; 图 9
Eisch V, Lu X, Gabriel D, Djabali K. Progerin impairs chromosome maintenance by depleting CENP-F from metaphase kinetochores in Hutchinson-Gilford progeria fibroblasts. Oncotarget. 2016;7:24700-18 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1
Xu X, Tan X, Hulshoff M, Wilhelmi T, Zeisberg M, Zeisberg E. Hypoxia-induced endothelial-mesenchymal transition is associated with RASAL1 promoter hypermethylation in human coronary endothelial cells. FEBS Lett. 2016;590:1222-33 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 2
Gschweitl M, Ulbricht A, Barnes C, Enchev R, Stoffel Studer I, Meyer Schaller N, et al. A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes. elife. 2016;5:e13841 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 2
Decorsière A, Mueller H, van Breugel P, Abdul F, Gerossier L, Beran R, et al. Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor. Nature. 2016;531:386-9 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Fong S, Lin H, Wu M, Chen C, Huang Y. CPEB3 Deficiency Elevates TRPV1 Expression in Dorsal Root Ganglia Neurons to Potentiate Thermosensation. PLoS ONE. 2016;11:e0148491 pubmed 出版商
  • 免疫印迹; 人类; 图 7f
Ro S, Xue X, Ramakrishnan S, Cho C, Namkoong S, Jang I, et al. Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis. elife. 2016;5:e12204 pubmed 出版商
  • 免疫印迹; 人类; 图 1
  • 免疫印迹; 小鼠; 图 2
Ladurner R, Kreidl E, Ivanov M, Ekker H, Idarraga Amado M, Busslinger G, et al. Sororin actively maintains sister chromatid cohesion. EMBO J. 2016;35:635-53 pubmed 出版商
  • 免疫印迹; 人类; 图 s11
Sancho Martinez I, Nivet E, Xia Y, Hishida T, Aguirre A, Ocampo A, et al. Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. Nat Commun. 2016;7:10743 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Sieber J, Hauer C, Bhuvanagiri M, Leicht S, Krijgsveld J, Neu Yilik G, et al. Proteomic Analysis Reveals Branch-specific Regulation of the Unfolded Protein Response by Nonsense-mediated mRNA Decay. Mol Cell Proteomics. 2016;15:1584-97 pubmed 出版商
  • 免疫印迹; 人类; 图 8
Gawron D, Ndah E, Gevaert K, Van Damme P. Positional proteomics reveals differences in N-terminal proteoform stability. Mol Syst Biol. 2016;12:858 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 4b
Bowles J, Feng C, Miles K, Ineson J, Spiller C, Koopman P. ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries. Nat Commun. 2016;7:10845 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Zhang Q, Gao X, Li C, Feliciano C, Wang D, Zhou D, et al. Impaired Dendritic Development and Memory in Sorbs2 Knock-Out Mice. J Neurosci. 2016;36:2247-60 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 4
  • 免疫印迹; 仓鼠; 1:10,000; 图 7
Prabhu A, Luu W, Sharpe L, Brown A. Cholesterol-mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis. J Biol Chem. 2016;291:8363-73 pubmed 出版商
  • 免疫印迹; 人类
Hoffmann C, Mao X, Dieterle M, Moreau F, Al Absi A, Steinmetz A, et al. CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis. Oncotarget. 2016;7:13688-705 pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 5b
  • 免疫印迹; 小鼠; 1:3000; 图 6f
Alonso F, Domingos Pereira S, Le Gal L, Derré L, Meda P, Jichlinski P, et al. Targeting endothelial connexin40 inhibits tumor growth by reducing angiogenesis and improving vessel perfusion. Oncotarget. 2016;7:14015-28 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 9
Taverna E, Mora Bermúdez F, Strzyz P, Florio M, Icha J, Haffner C, et al. Non-canonical features of the Golgi apparatus in bipolar epithelial neural stem cells. Sci Rep. 2016;6:21206 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Kim D, Helfman D. Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling. Oncogene. 2016;35:4495-508 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Khalid S, Drasche A, Thurner M, Hermann M, Ashraf M, Fresser F, et al. cJun N-terminal kinase (JNK) phosphorylation of serine 36 is critical for p66Shc activation. Sci Rep. 2016;6:20930 pubmed 出版商
  • 免疫印迹; 人类; 1:4000; 图 1
Kim N, Kim M, Sung P, Bae Y, Shin E, Yoo J. Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A. Nat Commun. 2016;7:10631 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Liu C, Rajapakse A, Riedo E, Fellay B, Bernhard M, Montani J, et al. Targeting arginase-II protects mice from high-fat-diet-induced hepatic steatosis through suppression of macrophage inflammation. Sci Rep. 2016;6:20405 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Nagy Z, Kalousi A, Furst A, Koch M, Fischer B, Soutoglou E. Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs. PLoS Genet. 2016;12:e1005791 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Lancaster G, Kammoun H, Kraakman M, Kowalski G, Bruce C, Febbraio M. PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications. Nat Commun. 2016;7:10626 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 7
Marmugi A, Parnis J, Chen X, Carmichael L, Hardy J, Mannan N, et al. Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca2+ Stores. Diabetes. 2016;65:1009-21 pubmed 出版商
  • 免疫细胞化学; 大鼠; 图 6i
Yau K, Schätzle P, Tortosa E, Pagès S, Holtmaat A, Kapitein L, et al. Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation. J Neurosci. 2016;36:1071-85 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 2
Tan X, Xu X, Zeisberg M, Zeisberg E. DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition. PLoS ONE. 2016;11:e0147816 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 2
  • 免疫印迹; 小鼠; 1:3000; 图 2
Grego Bessa J, Bloomekatz J, Castel P, Omelchenko T, Baselga J, Anderson K. The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium. elife. 2016;5:e12034 pubmed 出版商
  • 免疫细胞化学; 鸡; 图 3
  • 免疫印迹; 鸡; 1:2000; 图 2
Wood L, Booth D, Vargiu G, Ohta S, deLima Alves F, Samejima K, et al. Auxin/AID versus conventional knockouts: distinguishing the roles of CENP-T/W in mitotic kinetochore assembly and stability. Open Biol. 2016;6:150230 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s1
Choi S, Chen Z, Tang L, Fang Y, Shin S, Panarelli N, et al. Bcl-xL promotes metastasis independent of its anti-apoptotic activity. Nat Commun. 2016;7:10384 pubmed 出版商
  • 免疫印迹; 人类; 图 1
  • 免疫印迹; 小鼠; 图 1
Du Y, Yamaguchi H, Wei Y, Hsu J, Wang H, Hsu Y, et al. Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors. Nat Med. 2016;22:194-201 pubmed 出版商
  • 免疫印迹; 小鼠; 1:25,000; 图 s4c
Avgustinova A, Iravani M, Robertson D, Fearns A, Gao Q, Klingbeil P, et al. Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness. Nat Commun. 2016;7:10305 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Cherepkova M, Sineva G, Pospelov V. Leukemia inhibitory factor (LIF) withdrawal activates mTOR signaling pathway in mouse embryonic stem cells through the MEK/ERK/TSC2 pathway. Cell Death Dis. 2016;7:e2050 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s2
Quétier I, Marshall J, Spencer Dene B, Lachmann S, Casamassima A, Franco C, et al. Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion. Cell Rep. 2016;14:440-448 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Choi Y, Meghani K, Brault M, Leclerc L, He Y, Day T, et al. Platinum and PARP Inhibitor Resistance Due to Overexpression of MicroRNA-622 in BRCA1-Mutant Ovarian Cancer. Cell Rep. 2016;14:429-439 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1c
Yang Y, Li W, Hoque M, Hou L, Shen S, Tian B, et al. PAF Complex Plays Novel Subunit-Specific Roles in Alternative Cleavage and Polyadenylation. PLoS Genet. 2016;12:e1005794 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Ketel K, Krauss M, Nicot A, Puchkov D, Wieffer M, Müller R, et al. A phosphoinositide conversion mechanism for exit from endosomes. Nature. 2016;529:408-12 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Puvirajesinghe T, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer. Nat Commun. 2016;7:10318 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 2
Ruegsegger C, Stucki D, Steiner S, Angliker N, Radecke J, Keller E, et al. Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology. Neuron. 2016;89:129-46 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Wang M, Itoh M, Li S, Hida Y, Ohta K, Hayakawa M, et al. CED-4 is an mRNA-binding protein that delivers ced-3 mRNA to ribosomes. Biochem Biophys Res Commun. 2016;470:48-53 pubmed 出版商
  • 免疫印迹; 人类; 1:8000; 图 4
Lee S, Frattini V, Bansal M, Castano A, Sherman D, Hutchinson K, et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016;529:172-7 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 1
Drusenheimer N, Migdal B, Jäckel S, Tveriakhina L, Scheider K, Schulz K, et al. The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling. PLoS Genet. 2015;11:e1005749 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 1
Gomez Villafuertes R, García Huerta P, Díaz Hernández J, Miras Portugal M. PI3K/Akt signaling pathway triggers P2X7 receptor expression as a pro-survival factor of neuroblastoma cells under limiting growth conditions. Sci Rep. 2015;5:18417 pubmed 出版商
  • 免疫印迹; 人类; 1:4000; 图 5
Wille C, Nawandar D, Henning A, Ma S, Oetting K, Lee D, et al. 5-hydroxymethylation of the EBV genome regulates the latent to lytic switch. Proc Natl Acad Sci U S A. 2015;112:E7257-65 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Pillai S, Nguyen J, Johnson J, Haura E, Coppola D, Chellappan S. Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis. Nat Commun. 2015;6:10072 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 3
Dobrowolny G, Bernardini C, Martini M, Baranzini M, Barba M, Musarò A. Muscle Expression of SOD1(G93A) Modulates microRNA and mRNA Transcription Pattern Associated with the Myelination Process in the Spinal Cord of Transgenic Mice. Front Cell Neurosci. 2015;9:463 pubmed 出版商
  • 免疫印迹; 斑马鱼; 1:10,000; 图 1
Veldman M, Rios Galdamez Y, Lu X, Gu X, Qin W, Li S, et al. The N17 domain mitigates nuclear toxicity in a novel zebrafish Huntington's disease model. Mol Neurodegener. 2015;10:67 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Lommel M, Trairatphisan P, Gäbler K, Laurini C, Muller A, Kaoma T, et al. L-plastin Ser5 phosphorylation in breast cancer cells and in vitro is mediated by RSK downstream of the ERK/MAPK pathway. FASEB J. 2016;30:1218-33 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 6
Qian G, Fan W, Ahlemeyer B, Karnati S, Baumgart Vogt E. Peroxisomes in Different Skeletal Cell Types during Intramembranous and Endochondral Ossification and Their Regulation during Osteoblast Differentiation by Distinct Peroxisome Proliferator-Activated Receptors. PLoS ONE. 2015;10:e0143439 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
Qi D, Kaur Gill N, Santiskulvong C, Sifuentes J, Dorigo O, Rao J, et al. Screening cell mechanotype by parallel microfiltration. Sci Rep. 2015;5:17595 pubmed 出版商
  • 免疫细胞化学; 人类; 1:10,000; 图 s2
Etemad B, Kuijt T, Kops G. Kinetochore-microtubule attachment is sufficient to satisfy the human spindle assembly checkpoint. Nat Commun. 2015;6:8987 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Fukuda M, Inoue M, Muramatsu D, Miyachi H, Shinkai Y. Knockout mouse production assisted by Blm knockdown. J Reprod Dev. 2016;62:121-5 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 2
Dewaele M, Tabaglio T, Willekens K, Bezzi M, Teo S, Low D, et al. Antisense oligonucleotide-mediated MDM4 exon 6 skipping impairs tumor growth. J Clin Invest. 2016;126:68-84 pubmed 出版商
  • 免疫组化; 大豆; 1:800
Gzyl J, Chmielowska BÄ…k J, PrzymusiÅ„ski R, Gwóźdź E. Cadmium affects microtubule organization and post-translational modifications of tubulin in seedlings of soybean (Glycine max L.). Front Plant Sci. 2015;6:937 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Cristini A, Park J, Capranico G, Legube G, Favre G, Sordet O. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res. 2016;44:1161-78 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 12
  • 免疫印迹; 小鼠; 图 12
Copeland S, Thurston S, Copeland J. Actin- and microtubule-dependent regulation of Golgi morphology by FHDC1. Mol Biol Cell. 2016;27:260-76 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 ev3
Fernández Santiago R, Carballo Carbajal I, Castellano G, Torrent R, Richaud Y, Sánchez Danés A, et al. Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients. EMBO Mol Med. 2015;7:1529-46 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s4
Antonucci L, Fagman J, Kim J, Todoric J, Gukovsky I, Mackey M, et al. Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress. Proc Natl Acad Sci U S A. 2015;112:E6166-74 pubmed 出版商
  • 免疫印迹; 人类
Eiseler T, Wille C, Koehler C, Illing A, Seufferlein T. Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion. J Biol Chem. 2016;291:462-77 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
Fuchs M, Luthold C, Guilbert S, Varlet A, Lambert H, Jetté A, et al. A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis. PLoS Genet. 2015;11:e1005582 pubmed 出版商
  • 免疫印迹; 人类; 图 s7
Tonsing Carter E, Bailey B, Saadatzadeh M, Ding J, Wang H, Sinn A, et al. Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model. Mol Cancer Ther. 2015;14:2850-63 pubmed 出版商
  • 免疫印迹; 家羊; 1:1000; 图 1a
Teng R, Wu T, Afolayan A, Konduri G. Nitrotyrosine impairs mitochondrial function in fetal lamb pulmonary artery endothelial cells. Am J Physiol Cell Physiol. 2016;310:C80-8 pubmed 出版商
  • 免疫印迹; 小鼠; 1:50,000; 图 6
Bizet A, Becker Heck A, Ryan R, Weber K, Filhol E, Krug P, et al. Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization. Nat Commun. 2015;6:8666 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 6
Müller W, Schröder H, Tolba E, Diehl Seifert B, Wang X. Mineralization of bone-related SaOS-2 cells under physiological hypoxic conditions. FEBS J. 2016;283:74-87 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2b
Klar A, Gopinadh J, Kleber S, Wadle A, Renner C. Treatment with 5-Aza-2'-Deoxycytidine Induces Expression of NY-ESO-1 and Facilitates Cytotoxic T Lymphocyte-Mediated Tumor Cell Killing. PLoS ONE. 2015;10:e0139221 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Felli N, Errico M, Pedini F, Petrini M, Puglisi R, Bellenghi M, et al. AP2α controls the dynamic balance between miR-126&126* and miR-221&222 during melanoma progression. Oncogene. 2016;35:3016-26 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 3
Nawandar D, Wang A, Makielski K, Lee D, Ma S, Barlow E, et al. Differentiation-Dependent KLF4 Expression Promotes Lytic Epstein-Barr Virus Infection in Epithelial Cells. PLoS Pathog. 2015;11:e1005195 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
Voets E, Marsman J, Demmers J, Beijersbergen R, Wolthuis R. The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1. Sci Rep. 2015;5:14798 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Yokdang N, Hatakeyama J, Wald J, Simion C, Tellez J, Chang D, et al. LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells. Oncogene. 2016;35:2932-47 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Basheer W, Harris B, Mentrup H, Abreha M, Thames E, Lea J, et al. Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis. J Mol Cell Cardiol. 2015;88:1-13 pubmed 出版商
  • 免疫印迹; 人类; 1:2500; 图 2b
Ho D, Kim H, Kim J, Sim H, Ahn H, Kim J, et al. Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression. Mol Brain. 2015;8:54 pubmed 出版商
  • 免疫印迹; 人类; 1:30,000; 图 3c
D Amato N, Rogers T, Gordon M, Greene L, Cochrane D, Spoelstra N, et al. A TDO2-AhR signaling axis facilitates anoikis resistance and metastasis in triple-negative breast cancer. Cancer Res. 2015;75:4651-64 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Zagani R, El Assaad W, Gamache I, Teodoro J. Inhibition of adipose triglyceride lipase (ATGL) by the putative tumor suppressor G0S2 or a small molecule inhibitor attenuates the growth of cancer cells. Oncotarget. 2015;6:28282-95 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Zhou N, Yuan S, Wang R, Zhang W, Chen J. Role of dual specificity tyrosine-phosphorylation-regulated kinase 1B (Dyrk1B) in S-phase entry of HPV E7 expressing cells from quiescence. Oncotarget. 2015;6:30745-61 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 4
Kim S, Lee K, Choi J, Ringstad N, Dynlacht B. Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle. Nat Commun. 2015;6:8087 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1g
Galicia Vázquez G, Chu J, Pelletier J. eIF4AII is dispensable for miRNA-mediated gene silencing. RNA. 2015;21:1826-33 pubmed 出版商
  • 免疫印迹; 人类; 1:8000; 图 10a
Takata K, Tomida J, Reh S, Swanhart L, Takata M, Hukriede N, et al. Conserved overlapping gene arrangement, restricted expression, and biochemical activities of DNA polymerase ν (POLN). J Biol Chem. 2015;290:24278-93 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 1
  • 免疫印迹; 人类; 1:1000; 图 2
Kanfer G, Courtheoux T, Peterka M, Meier S, Soste M, Melnik A, et al. Mitotic redistribution of the mitochondrial network by Miro and Cenp-F. Nat Commun. 2015;6:8015 pubmed 出版商
  • 免疫印迹; 人类; 图 10
Genin M, Clement F, Fattaccioli A, Raes M, Michiels C. M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide. BMC Cancer. 2015;15:577 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Cymerman I, Gozdz A, Urbanska M, Milek J, Dziembowska M, Jaworski J. Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3β. PLoS ONE. 2015;10:e0134018 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s8
Sutani T, Sakata T, Nakato R, Masuda K, Ishibashi M, Yamashita D, et al. Condensin targets and reduces unwound DNA structures associated with transcription in mitotic chromosome condensation. Nat Commun. 2015;6:7815 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Navarro F, Lieberman J. miR-34 and p53: New Insights into a Complex Functional Relationship. PLoS ONE. 2015;10:e0132767 pubmed 出版商
  • 免疫印迹; 人类; 图 s6m
Li W, Hu Y, Oh S, Ma Q, Merkurjev D, Song X, et al. Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation. Mol Cell. 2015;59:188-202 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 3a
Rivas S, Armisén R, Rojas D, Maldonado E, Huerta H, Tapia J, et al. The Ski Protein is Involved in the Transformation Pathway of Aurora Kinase A. J Cell Biochem. 2016;117:334-43 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s1
Sadaie M, Dillon C, Narita M, Young A, Cairney C, Godwin L, et al. Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition. Mol Biol Cell. 2015;26:2971-85 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4b
Lebrun Julien F, Suter U. Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression. ASN Neuro. 2015;7: pubmed 出版商
  • 免疫印迹; 人类
Madrigal Matute J, Fernandez García C, Blanco Colio L, Burillo E, Fortuño A, Martinez Pinna R, et al. Thioredoxin-1/peroxiredoxin-1 as sensors of oxidative stress mediated by NADPH oxidase activity in atherosclerosis. Free Radic Biol Med. 2015;86:352-61 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Macvicar T, Mannack L, Lees R, Lane J. Targeted siRNA Screens Identify ER-to-Mitochondrial Calcium Exchange in Autophagy and Mitophagy Responses in RPE1 Cells. Int J Mol Sci. 2015;16:13356-80 pubmed 出版商
  • 免疫印迹; 人类
Galoian K, Qureshi A, D Ippolito G, Schiller P, Molinari M, Johnstone A, et al. Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1. Int J Oncol. 2015;47:465-72 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Heinemann A, Cullinane C, De Paoli Iseppi R, Wilmott J, Gunatilake D, Madore J, et al. Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling. Oncotarget. 2015;6:21507-21 pubmed
  • 免疫印迹; 人类
Faggi F, Codenotti S, Poliani P, Cominelli M, Chiarelli N, Colombi M, et al. MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line. PLoS ONE. 2015;10:e0130287 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 2
Aspalter I, Gordon E, Dubrac A, Ragab A, Narloch J, Vizan P, et al. Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch. Nat Commun. 2015;6:7264 pubmed 出版商
  • 免疫印迹; 小鼠; 1:4000; 图 1
Tian L, Ding S, You Y, Li T, Liu Y, Wu X, et al. Leiomodin-3-deficient mice display nemaline myopathy with fast-myofiber atrophy. Dis Model Mech. 2015;8:635-41 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 2
Moiseeva O, Lessard F, Acevedo Aquino M, Vernier M, Tsantrizos Y, Ferbeyre G. Mutant lamin A links prophase to a p53 independent senescence program. Cell Cycle. 2015;14:2408-21 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 4
Bosco D, Kenworthy R, Zorio D, Sang Q. Human mesenchymal stem cells are resistant to Paclitaxel by adopting a non-proliferative fibroblastic state. PLoS ONE. 2015;10:e0128511 pubmed 出版商
  • 免疫印迹; 小鼠
Tojo Y, Sekine H, Hirano I, Pan X, Souma T, Tsujita T, et al. Hypoxia Signaling Cascade for Erythropoietin Production in Hepatocytes. Mol Cell Biol. 2015;35:2658-72 pubmed 出版商
  • 免疫印迹; 人类
Yeh J, Kreimer S, Walker S, Emori M, Krystal H, Richardson A, et al. Granulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer. Genes Cancer. 2015;6:153-68 pubmed
  • 免疫印迹; 人类
Greenfeld H, Takasaki K, Walsh M, Ersing I, Bernhardt K, Ma Y, et al. TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation. PLoS Pathog. 2015;11:e1004890 pubmed 出版商
  • 免疫印迹; 人类; 1:50,000; 图 7
Heubach J, Monsior J, Deenen R, Niegisch G, Szarvas T, Niedworok C, et al. The long noncoding RNA HOTAIR has tissue and cell type-dependent effects on HOX gene expression and phenotype of urothelial cancer cells. Mol Cancer. 2015;14:108 pubmed 出版商
  • 免疫印迹; 人类
De Zio D, Molinari F, Rizza S, Gatta L, Ciotti M, Salvatore A, et al. Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth. Cell Mol Life Sci. 2015;72:4173-91 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Ketema M, Secades P, Kreft M, Nahidiazar L, Janssen H, Jalink K, et al. The rod domain is not essential for the function of plectin in maintaining tissue integrity. Mol Biol Cell. 2015;26:2402-17 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1
Prosser S, Sahota N, Pelletier L, Morrison C, Fry A. Nek5 promotes centrosome integrity in interphase and loss of centrosome cohesion in mitosis. J Cell Biol. 2015;209:339-48 pubmed 出版商
  • 免疫印迹; 人类
Bergeron D, Pal G, Beaulieu Y, Chabot B, Bachand F. Regulated Intron Retention and Nuclear Pre-mRNA Decay Contribute to PABPN1 Autoregulation. Mol Cell Biol. 2015;35:2503-17 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 1
  • 免疫印迹; 小鼠; 图 1
  • 免疫细胞化学; 犬; 图 1
  • 免疫印迹; 犬; 图 1
Castelli M, De Pascalis C, Distefano G, Ducano N, Oldani A, Lanzetti L, et al. Regulation of the microtubular cytoskeleton by Polycystin-1 favors focal adhesions turnover to modulate cell adhesion and migration. BMC Cell Biol. 2015;16:15 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200,000; 图 2
Liu P, Paulson J, Forster C, Shapiro S, Ashe K, Zahs K. Characterization of a Novel Mouse Model of Alzheimer's Disease--Amyloid Pathology and Unique β-Amyloid Oligomer Profile. PLoS ONE. 2015;10:e0126317 pubmed 出版商
  • 免疫印迹; 人类; 图 s3
Naipal K, Raams A, Bruens S, Brandsma I, Verkaik N, Jaspers N, et al. Attenuated XPC expression is not associated with impaired DNA repair in bladder cancer. PLoS ONE. 2015;10:e0126029 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
  • 免疫印迹; 人类; 图 1
Isogai T, van der Kammen R, Innocenti M. SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton. Sci Rep. 2015;5:9802 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Mishra D, Chaudhary S, Krishna B, Mishra S. Identification of Critical Elements for Regulation of Inorganic Pyrophosphatase (PPA1) in MCF7 Breast Cancer Cells. PLoS ONE. 2015;10:e0124864 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1
Caruso M, Ferranti F, Corano Scheri K, Dobrowolny G, Ciccarone F, Grammatico P, et al. R-spondin 1/dickkopf-1/beta-catenin machinery is involved in testicular embryonic angiogenesis. PLoS ONE. 2015;10:e0124213 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Sun Y, Ponz Sarvisé M, Chang S, Chang W, Chen C, Hsu J, et al. Proteasome inhibition enhances the killing effect of BikDD gene therapy. Am J Transl Res. 2015;7:319-27 pubmed
  • 免疫印迹; 人类
Pozo K, Hillmann A, Augustyn A, Plattner F, Hai T, Singh T, et al. Differential expression of cell cycle regulators in CDK5-dependent medullary thyroid carcinoma tumorigenesis. Oncotarget. 2015;6:12080-93 pubmed
  • 免疫印迹; 人类; 1:5000; 图 1
Khuperkar D, Helen M, Magre I, Joseph J. Inter-cellular transport of ran GTPase. PLoS ONE. 2015;10:e0125506 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
Brzoska E, Kowalski K, Markowska Zagrajek A, Kowalewska M, Archacki R, Plaskota I, et al. Sdf-1 (CXCL12) induces CD9 expression in stem cells engaged in muscle regeneration. Stem Cell Res Ther. 2015;6:46 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 4
Lu J, Luo C, Bali K, Xie R, Mains R, Eipper B, et al. A role for Kalirin-7 in nociceptive sensitization via activity-dependent modulation of spinal synapses. Nat Commun. 2015;6:6820 pubmed 出版商
  • 免疫印迹; 人类
Antonenkov V, Isomursu A, Mennerich D, Vapola M, Weiher H, Kietzmann T, et al. The Human Mitochondrial DNA Depletion Syndrome Gene MPV17 Encodes a Non-selective Channel That Modulates Membrane Potential. J Biol Chem. 2015;290:13840-61 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Ohashi M, Holthaus A, Calderwood M, Lai C, Krastins B, Sarracino D, et al. The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth. PLoS Pathog. 2015;11:e1004822 pubmed 出版商
  • 免疫印迹; 人类; 图 s6
Westcott J, Prechtl A, Maine E, Dang T, Esparza M, Sun H, et al. An epigenetically distinct breast cancer cell subpopulation promotes collective invasion. J Clin Invest. 2015;125:1927-43 pubmed 出版商
  • 免疫组化; 人类; 图 6
Bazellières E, Conte V, Elosegui Artola A, Serra Picamal X, Bintanel Morcillo M, Roca Cusachs P, et al. Control of cell-cell forces and collective cell dynamics by the intercellular adhesome. Nat Cell Biol. 2015;17:409-20 pubmed 出版商
  • 免疫印迹; 小鼠
Perdigão Henriques R, Petrocca F, Altschuler G, Thomas M, Le M, Tan S, et al. miR-200 promotes the mesenchymal to epithelial transition by suppressing multiple members of the Zeb2 and Snail1 transcriptional repressor complexes. Oncogene. 2016;35:158-72 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000
Philippou A, Minozzo F, Spinazzola J, Smith L, Lei H, Rassier D, et al. Masticatory muscles of mouse do not undergo atrophy in space. FASEB J. 2015;29:2769-79 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 3e
Han J, Song B, Kim J, Kodali V, Pottekat A, Wang M, et al. Antioxidants Complement the Requirement for Protein Chaperone Function to Maintain β-Cell Function and Glucose Homeostasis. Diabetes. 2015;64:2892-904 pubmed 出版商
  • 免疫印迹; 人类; 1:30000
Leclere L, Fransolet M, Côté F, Cambier P, Arnould T, Van Cutsem P, et al. Heat-modified citrus pectin induces apoptosis-like cell death and autophagy in HepG2 and A549 cancer cells. PLoS ONE. 2015;10:e0115831 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 1
Koh H, Chang C, Jeon S, Yoon H, Ahn Y, Kim H, et al. The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia. Nat Commun. 2015;6:6340 pubmed 出版商
  • 免疫印迹; 人类; 1:10000
Prosser S, Morrison C. Centrin2 regulates CP110 removal in primary cilium formation. J Cell Biol. 2015;208:693-701 pubmed 出版商
  • 免疫沉淀; 人类; 图 s3
Aguilar Arnal L, Katada S, Orozco Solis R, Sassone Corsi P. NAD(+)-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1. Nat Struct Mol Biol. 2015;22:312-8 pubmed 出版商
  • 免疫细胞化学; 人类
Voets E, Wolthuis R. MASTL promotes cyclin B1 destruction by enforcing Cdc20-independent binding of cyclin B1 to the APC/C. Biol Open. 2015;4:484-95 pubmed 出版商
  • 免疫组化; 人类; 1:3000; 图 3
Iemura K, Tanaka K. Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubules. Nat Commun. 2015;6:6447 pubmed 出版商
  • 免疫印迹; 人类
Martínez Torres A, Quiney C, Attout T, Boullet H, Herbi L, Vela L, et al. CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCγ1 activation: evidence from mice and humans. PLoS Med. 2015;12:e1001796 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 1:5000; 图 5
Thangavel S, Berti M, Levikova M, Pinto C, Gomathinayagam S, Vujanovic M, et al. DNA2 drives processing and restart of reversed replication forks in human cells. J Cell Biol. 2015;208:545-62 pubmed 出版商
  • 免疫印迹; 小鼠
Xiong J, Todorova D, Su N, Kim J, Lee P, Shen Z, et al. Stemness factor Sall4 is required for DNA damage response in embryonic stem cells. J Cell Biol. 2015;208:513-20 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Kratz A, Bärenz F, Richter K, Hoffmann I. Plk4-dependent phosphorylation of STIL is required for centriole duplication. Biol Open. 2015;4:370-7 pubmed 出版商
  • 免疫印迹; 人类
Wang Y, Tan B, Mu R, Chang Y, Wu M, Tu H, et al. Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling. J Biol Chem. 2015;290:10395-405 pubmed 出版商
  • 免疫细胞化学; 人类; 1:2000; 图 1a
Ohta S, Wood L, Toramoto I, Yagyu K, Fukagawa T, Earnshaw W. CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly. Mol Biol Cell. 2015;26:1225-37 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Guerrero A, Iglesias C, Raguz S, Floridia E, Gil J, Pombo C, et al. The cerebral cavernous malformation 3 gene is necessary for senescence induction. Aging Cell. 2015;14:274-83 pubmed 出版商
  • 免疫印迹; 人类
González N, Martín Duce A, Martínez Arrieta F, Moreno Villegas Z, Portal Núñez S, Sanz R, et al. Effect of bombesin receptor subtype-3 and its synthetic agonist on signaling, glucose transport and metabolism in myocytes from patients with obesity and type 2 diabetes. Int J Mol Med. 2015;35:925-31 pubmed 出版商
  • 免疫印迹; 人类
Michel S, Canonne M, Arnould T, Renard P. Inhibition of mitochondrial genome expression triggers the activation of CHOP-10 by a cell signaling dependent on the integrated stress response but not the mitochondrial unfolded protein response. Mitochondrion. 2015;21:58-68 pubmed 出版商
  • 免疫印迹; 人类
Kozlova N, Samoylenko A, Drobot L, Kietzmann T. Urokinase is a negative modulator of Egf-dependent proliferation and motility in the two breast cancer cell lines MCF-7 and MDA-MB-231. Mol Carcinog. 2016;55:170-81 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Kwun H, Shuda M, Camacho C, Gamper A, Thant M, Chang Y, et al. Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen. J Virol. 2015;89:4191-200 pubmed 出版商
  • 免疫印迹; 小鼠; 1:8000; 图 2
Piatti P, Lim C, Nat R, Villunger A, Geley S, Shue Y, et al. Embryonic stem cell differentiation requires full length Chd1. Sci Rep. 2015;5:8007 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s4
  • 免疫印迹; 人类; 图 1
Bele A, Mirza S, Zhang Y, Ahmad Mir R, Lin S, Kim J, et al. The cell cycle regulator ecdysoneless cooperates with H-Ras to promote oncogenic transformation of human mammary epithelial cells. Cell Cycle. 2015;14:990-1000 pubmed 出版商
  • 免疫印迹; 人类; 1:20,000; 图 1
Niemeyer B, Parrish J, Spoelstra N, Joyal T, Richer J, Jedlicka P. Variable expression of PIK3R3 and PTEN in Ewing Sarcoma impacts oncogenic phenotypes. PLoS ONE. 2015;10:e0116895 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 4B
  • 免疫印迹; 人类; 1:1000; 图 1A
Silva V, Plooster M, Leung J, Cassimeris L. A delay prior to mitotic entry triggers caspase 8-dependent cell death in p53-deficient Hela and HCT-116 cells. Cell Cycle. 2015;14:1070-81 pubmed 出版商
  • 免疫细胞化学; 猕猴; 图 2
van Bergeijk P, Adrian M, Hoogenraad C, Kapitein L. Optogenetic control of organelle transport and positioning. Nature. 2015;518:111-114 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 6
Renard H, Simunovic M, Lemière J, Boucrot E, Garcia Castillo M, Arumugam S, et al. Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis. Nature. 2015;517:493-6 pubmed 出版商
  • 免疫印迹; 小鼠; 1:4000
Katsunuma K, Yoshinaga K, Ohira Y, Eta R, Sato T, Horii T, et al. Z-100, extracted from Mycobacterium tuberculosis strain Aoyama B, promotes TNF-α production via nucleotide-binding oligomerization domain containing 2 (Nod2)-dependent NF-κB activation in RAW264.7 cells. Mol Immunol. 2015;64:218-27 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Shen W, Li H, Chen G, Chern Y, Tu P. Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism. Autophagy. 2015;11:685-700 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Diesenberg K, Beerbaum M, Fink U, Schmieder P, Krauss M. SEPT9 negatively regulates ubiquitin-dependent downregulation of EGFR. J Cell Sci. 2015;128:397-407 pubmed 出版商
  • 免疫印迹; 小鼠; 1:8000; 图 1
Meng L, Ward A, Chun S, Bennett C, Beaudet A, Rigo F. Towards a therapy for Angelman syndrome by targeting a long non-coding RNA. Nature. 2015;518:409-12 pubmed 出版商
  • 免疫印迹; 人类; 1:10000; 图 s1
Nijenhuis W, Vallardi G, Teixeira A, Kops G, Saurin A. Negative feedback at kinetochores underlies a responsive spindle checkpoint signal. Nat Cell Biol. 2014;16:1257-64 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Chen J, Shin J, Zhao R, Phan L, Wang H, Xue Y, et al. CSN6 drives carcinogenesis by positively regulating Myc stability. Nat Commun. 2014;5:5384 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Komaravolu R, Adam C, Moonen J, Harmsen M, Goebeler M, Schmidt M. Erk5 inhibits endothelial migration via KLF2-dependent down-regulation of PAK1. Cardiovasc Res. 2015;105:86-95 pubmed 出版商
  • 免疫印迹; 小鼠; 1:4000; 图 f7s2
Katz Y, Li F, Lambert N, Sokol E, Tam W, Cheng A, et al. Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state. elife. 2014;3:e03915 pubmed 出版商
  • 免疫印迹; fruit fly ; 1:2000
Carmena M, Lombardía M, Ogawa H, Earnshaw W. Polo kinase regulates the localization and activity of the chromosomal passenger complex in meiosis and mitosis in Drosophila melanogaster. Open Biol. 2014;4:140162 pubmed 出版商
  • 免疫印迹; 人类
Kim K, Ossipova O, Sokol S. Neural crest specification by inhibition of the ROCK/Myosin II pathway. Stem Cells. 2015;33:674-85 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:5000
  • 免疫细胞化学; 人类; 1:500
Sun Q, Luo T, Ren Y, Florey O, Shirasawa S, Sasazuki T, et al. Competition between human cells by entosis. Cell Res. 2014;24:1299-310 pubmed 出版商
  • 免疫印迹; 人类
Nishibuchi G, Machida S, Osakabe A, Murakoshi H, Hiragami Hamada K, Nakagawa R, et al. N-terminal phosphorylation of HP1α increases its nucleosome-binding specificity. Nucleic Acids Res. 2014;42:12498-511 pubmed 出版商
  • 免疫印迹; 人类; 图 5
  • 免疫印迹; 小鼠; 图 2
Van der Meulen J, Sanghvi V, Mavrakis K, Durinck K, Fang F, Matthijssens F, et al. The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia. Blood. 2015;125:13-21 pubmed 出版商
  • 免疫印迹; 人类; 1:4000
Van Deun J, Mestdagh P, Sormunen R, Cocquyt V, Vermaelen K, Vandesompele J, et al. The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling. J Extracell Vesicles. 2014;3: pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, et al. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex. J Exp Med. 2014;211:2249-63 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Charlaftis N, Suddason T, Wu X, Anwar S, Karin M, Gallagher E. The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines. EMBO J. 2014;33:2581-96 pubmed 出版商
  • 免疫印迹; 小鼠
Gelfand M, Hagan N, Tata A, Oh W, Lacoste B, Kang K, et al. Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding. elife. 2014;3:e03720 pubmed 出版商
  • 免疫细胞化学; 人类
Wrzesinski K, Rogowska Wrzesinska A, Kanlaya R, Borkowski K, Schwämmle V, Dai J, et al. The cultural divide: exponential growth in classical 2D and metabolic equilibrium in 3D environments. PLoS ONE. 2014;9:e106973 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
Yanagi T, Krajewska M, Matsuzawa S, Reed J. PCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells. Cancer Res. 2014;74:5795-807 pubmed 出版商
  • 免疫印迹; 小鼠
Saini Y, Dang H, Livraghi Butrico A, Kelly E, Jones L, O Neal W, et al. Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration. BMC Genomics. 2014;15:726 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000
Rharass T, Lemcke H, Lantow M, Kuznetsov S, Weiss D, Panàkovà D. Ca2+-mediated mitochondrial reactive oxygen species metabolism augments Wnt/?-catenin pathway activation to facilitate cell differentiation. J Biol Chem. 2014;289:27937-51 pubmed 出版商
  • 免疫印迹; 人类
Bazot Q, Deschamps T, Tafforeau L, Siouda M, Leblanc P, Harth Hertle M, et al. Epstein-Barr virus nuclear antigen 3A protein regulates CDKN2B transcription via interaction with MIZ-1. Nucleic Acids Res. 2014;42:9700-16 pubmed 出版商
  • 免疫印迹; 小鼠
  • 免疫印迹; 人类
Vassilopoulos A, Tominaga Y, Kim H, Lahusen T, Li B, Yu H, et al. WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis. Oncogene. 2015;34:3023-35 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
Silva P, Reis R, Bolanos Garcia V, Florindo C, Tavares A, Bousbaa H. Dynein-dependent transport of spindle assembly checkpoint proteins off kinetochores toward spindle poles. FEBS Lett. 2014;588:3265-73 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000
Requejo Aguilar R, Lopez Fabuel I, Fernandez E, Martins L, Almeida A, Bolanos J. PINK1 deficiency sustains cell proliferation by reprogramming glucose metabolism through HIF1. Nat Commun. 2014;5:4514 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
  • 免疫沉淀; 小鼠
  • 免疫细胞化学; 小鼠
  • 免疫印迹; 小鼠
Ro S, Semple I, Park H, Park H, Park H, Kim M, et al. Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1. FEBS J. 2014;281:3816-27 pubmed 出版商
  • 免疫印迹; 小鼠; 1:20,000; 图 3
Moorwood C, Philippou A, Spinazzola J, Keyser B, Macarak E, Barton E. Absence of ?-sarcoglycan alters the response of p70S6 kinase to mechanical perturbation in murine skeletal muscle. Skelet Muscle. 2014;4:13 pubmed 出版商
  • 免疫印迹; 人类
Mungamuri S, Wang S, Manfredi J, Gu W, Aaronson S. Ash2L enables P53-dependent apoptosis by favoring stable transcription pre-initiation complex formation on its pro-apoptotic target promoters. Oncogene. 2015;34:2461-70 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Chondrogiannis G, Kastamoulas M, Kanavaros P, Vartholomatos G, Bai M, Baltogiannis D, et al. Cytokine effects on cell viability and death of prostate carcinoma cells. Biomed Res Int. 2014;2014:536049 pubmed 出版商
  • 免疫印迹; 大鼠
Fernandes J, Vieira M, Carreto L, Santos M, Duarte C, Carvalho A, et al. In vitro ischemia triggers a transcriptional response to down-regulate synaptic proteins in hippocampal neurons. PLoS ONE. 2014;9:e99958 pubmed 出版商
  • 免疫细胞化学; 犬; 1:200
  • 免疫印迹; 犬; 1:1000; 图 7
  • 免疫细胞化学; 人类; 1:200
Glotfelty L, Zahs A, Hodges K, Shan K, Alto N, Hecht G. Enteropathogenic E. coli effectors EspG1/G2 disrupt microtubules, contribute to tight junction perturbation and inhibit restoration. Cell Microbiol. 2014;16:1767-83 pubmed 出版商
  • 免疫组化; 人类; 图 3
Antanavičiūtė I, Rysevaite K, Liutkevicius V, Marandykina A, Rimkute L, Sveikatiene R, et al. Long-distance communication between laryngeal carcinoma cells. PLoS ONE. 2014;9:e99196 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Qiu W, Kassem M. miR-141-3p inhibits human stromal (mesenchymal) stem cell proliferation and differentiation. Biochim Biophys Acta. 2014;1843:2114-21 pubmed 出版商
  • 免疫印迹; 小鼠
Mamouni K, Cristini A, Guirouilh Barbat J, Monferran S, Lemarie A, Faye J, et al. RhoB promotes ?H2AX dephosphorylation and DNA double-strand break repair. Mol Cell Biol. 2014;34:3144-55 pubmed 出版商
  • 免疫印迹; 小鼠
Premkumar M, Sule G, Nagamani S, Chakkalakal S, Nordin A, Jain M, et al. Argininosuccinate lyase in enterocytes protects from development of necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol. 2014;307:G347-54 pubmed 出版商
  • 免疫印迹; 人类
Sung P, Murayama A, Kang W, Kim M, Yoon S, Fukasawa M, et al. Hepatitis C virus entry is impaired by claudin-1 downregulation in diacylglycerol acyltransferase-1-deficient cells. J Virol. 2014;88:9233-44 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Fernandes K, Harder J, JOHN S, Shrager P, Libby R. DLK-dependent signaling is important for somal but not axonal degeneration of retinal ganglion cells following axonal injury. Neurobiol Dis. 2014;69:108-16 pubmed 出版商
  • 免疫细胞化学; 人类
Ling Y, Wong C, Li K, Chan K, Boukamp P, Liu W. CCHCR1 interacts with EDC4, suggesting its localization in P-bodies. Exp Cell Res. 2014;327:12-23 pubmed 出版商
  • 免疫印迹; 小鼠
Godde N, Sheridan J, Smith L, Pearson H, Britt K, Galea R, et al. Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland. PLoS Genet. 2014;10:e1004323 pubmed 出版商
  • 免疫印迹; 人类
Choi Y, Pan Y, Park E, Konstantinopoulos P, De S, D ANDREA A, et al. MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability. elife. 2014;3:e02445 pubmed 出版商
  • 免疫印迹; 人类; 1:10000
Hans F, Fiesel F, Strong J, J ckel S, Rasse T, Geisler S, et al. UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 protein ubiquitination. J Biol Chem. 2014;289:19164-79 pubmed 出版商
  • 免疫印迹; 人类
Barrios A, Gómez A, Sáez J, Ciossani G, Toffolo E, Battaglioli E, et al. Differential properties of transcriptional complexes formed by the CoREST family. Mol Cell Biol. 2014;34:2760-70 pubmed
  • 免疫印迹; 人类; 1:5000
Zhu Y, Liu C, Cui Y, Nadiminty N, Lou W, Gao A. Interleukin-6 induces neuroendocrine differentiation (NED) through suppression of RE-1 silencing transcription factor (REST). Prostate. 2014;74:1086-94 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Ma L, Aslanian A, Sun H, Jin M, Shi Y, Yates J, et al. Identification of small ubiquitin-like modifier substrates with diverse functions using the Xenopus egg extract system. Mol Cell Proteomics. 2014;13:1659-75 pubmed 出版商
  • 免疫印迹; 酵母菌目
  • 免疫印迹; fission yeast
Okada N, Toda T, Yamamoto M, Sato M. CDK-dependent phosphorylation of Alp7-Alp14 (TACC-TOG) promotes its nuclear accumulation and spindle microtubule assembly. Mol Biol Cell. 2014;25:1969-82 pubmed 出版商
  • 免疫印迹; 人类
Negishi M, Wongpalee S, Sarkar S, Park J, Lee K, Shibata Y, et al. A new lncRNA, APTR, associates with and represses the CDKN1A/p21 promoter by recruiting polycomb proteins. PLoS ONE. 2014;9:e95216 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Rydell G, Renard H, Garcia Castillo M, Dingli F, Loew D, Lamaze C, et al. Rab12 localizes to Shiga toxin-induced plasma membrane invaginations and controls toxin transport. Traffic. 2014;15:772-87 pubmed 出版商
  • 免疫印迹; 人类
Kuijt T, Omerzu M, Saurin A, Kops G. Conditional targeting of MAD1 to kinetochores is sufficient to reactivate the spindle assembly checkpoint in metaphase. Chromosoma. 2014;123:471-80 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500
Daems C, Martin L, Brousseau C, Tremblay J. MEF2 is restricted to the male gonad and regulates expression of the orphan nuclear receptor NR4A1. Mol Endocrinol. 2014;28:886-98 pubmed 出版商
  • 免疫印迹; 小鼠
Sutherland J, Fraser B, Sobinoff A, Pye V, Davidson T, Siddall N, et al. Developmental expression of Musashi-1 and Musashi-2 RNA-binding proteins during spermatogenesis: analysis of the deleterious effects of dysregulated expression. Biol Reprod. 2014;90:92 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Dubois V, Laurent M, Sinnesael M, Cielen N, Helsen C, Clinckemalie L, et al. A satellite cell-specific knockout of the androgen receptor reveals myostatin as a direct androgen target in skeletal muscle. FASEB J. 2014;28:2979-94 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Turgay Y, Champion L, Balázs C, Held M, Toso A, Gerlich D, et al. SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown. J Cell Biol. 2014;204:1099-109 pubmed 出版商
  • 免疫印迹; 人类
Waitkus M, Chandrasekharan U, Willard B, Tee T, Hsieh J, Przybycin C, et al. Signal integration and gene induction by a functionally distinct STAT3 phosphoform. Mol Cell Biol. 2014;34:1800-11 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
  • 免疫印迹; 人类; 图 6
Meehan A, Saenz D, Guevera R, Morrison J, Peretz M, Fadel H, et al. A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection. PLoS Pathog. 2014;10:e1003969 pubmed 出版商
  • 免疫印迹; 人类
Khan K, Schneider Poetsch T, Ishfaq M, Ito A, Yoshimoto R, Mukaida N, et al. Splicing inhibition induces gene expression through canonical NF-?B pathway and extracellular signal-related kinase activation. FEBS Lett. 2014;588:1053-7 pubmed 出版商
  • 免疫印迹; 人类
Gonçalves V, Henriques A, Henriques A, Pereira J, Pereira J, Neves Costa A, et al. Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells. RNA. 2014;20:474-82 pubmed 出版商
  • 免疫印迹; 小鼠
Wang Y, Kuramitsu Y, Tokuda K, Okada F, Baron B, Akada J, et al. Proteomic analysis indicates that overexpression and nuclear translocation of lactoylglutathione lyase (GLO1) is associated with tumor progression in murine fibrosarcoma. Electrophoresis. 2014;35:2195-202 pubmed 出版商
  • 免疫印迹; 人类
Martínez Diez M, Guillén Navarro M, Pera B, Bouchet B, Martinez Leal J, Barasoain I, et al. PM060184, a new tubulin binding agent with potent antitumor activity including P-glycoprotein over-expressing tumors. Biochem Pharmacol. 2014;88:291-302 pubmed 出版商
  • 免疫印迹; 人类
Cheng Y, Holloway M, Nguyen K, McCauley D, Landesman Y, Kauffman M, et al. XPO1 (CRM1) inhibition represses STAT3 activation to drive a survivin-dependent oncogenic switch in triple-negative breast cancer. Mol Cancer Ther. 2014;13:675-86 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
  • 免疫印迹; 人类; 图 1
Potthoff E, Franco D, D Alessandro V, Starck C, Falk V, Zambelli T, et al. Toward a rational design of surface textures promoting endothelialization. Nano Lett. 2014;14:1069-79 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1, 2
Ashraf M, Ebner M, Wallner C, Haller M, Khalid S, Schwelberger H, et al. A p38MAPK/MK2 signaling pathway leading to redox stress, cell death and ischemia/reperfusion injury. Cell Commun Signal. 2014;12:6 pubmed 出版商
  • 免疫细胞化学; 人类
Diagouraga B, Grichine A, Fertin A, Wang J, Khochbin S, Sadoul K. Motor-driven marginal band coiling promotes cell shape change during platelet activation. J Cell Biol. 2014;204:177-85 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5, 7
Zemljic Harpf A, Godoy J, Platoshyn O, Asfaw E, Busija A, Domenighetti A, et al. Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes. J Cell Sci. 2014;127:1104-16 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
Honarpour N, Rose C, Brumbaugh J, Anderson J, Graham R, Sweredoski M, et al. F-box protein FBXL16 binds PP2A-B55? and regulates differentiation of embryonic stem cells along the FLK1+ lineage. Mol Cell Proteomics. 2014;13:780-91 pubmed 出版商
  • 免疫印迹; 人类
D Anselmi F, Masiello M, Cucina A, Proietti S, Dinicola S, Pasqualato A, et al. Microenvironment promotes tumor cell reprogramming in human breast cancer cell lines. PLoS ONE. 2013;8:e83770 pubmed 出版商
  • 免疫印迹; 人类
Miura S, Hamada S, Masamune A, Satoh K, Shimosegawa T. CUB-domain containing protein 1 represses the epithelial phenotype of pancreatic cancer cells. Exp Cell Res. 2014;321:209-18 pubmed 出版商
  • 免疫印迹; 人类
Chen Y, Thang M, Chan Y, Huang Y, Ma N, Yu A, et al. Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. PLoS ONE. 2013;8:e82751 pubmed 出版商
  • 免疫印迹; 非洲爪蛙
Chu C, Gerstenzang E, Ossipova O, Sokol S. Lulu regulates Shroom-induced apical constriction during neural tube closure. PLoS ONE. 2013;8:e81854 pubmed 出版商
  • 免疫印迹; fission yeast; 1:30000
Rødland G, Tvegård T, Boye E, Grallert B. Crosstalk between the Tor and Gcn2 pathways in response to different stresses. Cell Cycle. 2014;13:453-61 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Liu X, Xiao W, Wang X, Li Y, Han J, Li Y. The p38-interacting protein (p38IP) regulates G2/M progression by promoting ?-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5. J Biol Chem. 2013;288:36648-61 pubmed 出版商
  • 免疫细胞化学; 人类
Singh A, Zapata M, Choi Y, Yoon S. GSI promotes vincristine-induced apoptosis by enhancing multi-polar spindle formation. Cell Cycle. 2014;13:157-66 pubmed 出版商
  • 免疫印迹; 人类; 图 2
de Poot S, Lai K, van der Wal L, Plasman K, Van Damme P, Porter A, et al. Granzyme M targets topoisomerase II alpha to trigger cell cycle arrest and caspase-dependent apoptosis. Cell Death Differ. 2014;21:416-26 pubmed 出版商
  • 免疫印迹; 人类
Eldin P, Chazal N, Fenard D, Bernard E, Guichou J, Briant L. Vpr expression abolishes the capacity of HIV-1 infected cells to repair uracilated DNA. Nucleic Acids Res. 2014;42:1698-710 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6
Pazos P, Lima L, Casanueva F, Dieguez C, Garcia M. Interleukin 6 deficiency modulates the hypothalamic expression of energy balance regulating peptides during pregnancy in mice. PLoS ONE. 2013;8:e72339 pubmed 出版商
  • 免疫印迹; 人类
Hosogane M, Funayama R, Nishida Y, Nagashima T, Nakayama K. Ras-induced changes in H3K27me3 occur after those in transcriptional activity. PLoS Genet. 2013;9:e1003698 pubmed 出版商
  • 免疫印迹; 小鼠
Lu J, Chang Y, Wang C, Lin Y, Lin C, Wu Z. Trichostatin A modulates thiazolidinedione-mediated suppression of tumor necrosis factor ?-induced lipolysis in 3T3-L1 adipocytes. PLoS ONE. 2013;8:e71517 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000
  • 免疫印迹; 人类; 1:1000
Tan E, Caro S, Potnis A, Lanza C, Slawson C. O-linked N-acetylglucosamine cycling regulates mitotic spindle organization. J Biol Chem. 2013;288:27085-99 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Boutros R, Mondesert O, Lorenzo C, Astuti P, McArthur G, Chircop M, et al. CDC25B overexpression stabilises centrin 2 and promotes the formation of excess centriolar foci. PLoS ONE. 2013;8:e67822 pubmed 出版商
  • 免疫印迹; 小鼠
van Boxtel R, Gomez Puerto C, Mokry M, Eijkelenboom A, van der Vos K, Nieuwenhuis E, et al. FOXP1 acts through a negative feedback loop to suppress FOXO-induced apoptosis. Cell Death Differ. 2013;20:1219-29 pubmed 出版商
  • 免疫印迹; 人类
Li W, Notani D, Ma Q, Tanasa B, Nunez E, Chen A, et al. Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature. 2013;498:516-20 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Tomida J, Itaya A, Shigechi T, Unno J, Uchida E, Ikura M, et al. A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair. Nucleic Acids Res. 2013;41:6930-41 pubmed 出版商
  • 免疫印迹; 大鼠
Kolupaeva V, Daempfling L, Basilico C. The B55? regulatory subunit of protein phosphatase 2A mediates fibroblast growth factor-induced p107 dephosphorylation and growth arrest in chondrocytes. Mol Cell Biol. 2013;33:2865-78 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Przewoźniak M, Czaplicka I, Czerwinska A, Markowska Zagrajek A, Moraczewski J, Stremińska W, et al. Adhesion proteins--an impact on skeletal myoblast differentiation. PLoS ONE. 2013;8:e61760 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10000
  • 免疫印迹; 人类; 1:10000
Scaramuzzino C, Monaghan J, Milioto C, Lanson N, Maltare A, Aggarwal T, et al. Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo. PLoS ONE. 2013;8:e61576 pubmed 出版商
  • 免疫印迹; 大鼠; 1:10,000
Li X, Xiao Z, Han J, Chen L, Xiao H, Ma F, et al. Promotion of neuronal differentiation of neural progenitor cells by using EGFR antibody functionalized collagen scaffolds for spinal cord injury repair. Biomaterials. 2013;34:5107-16 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000
Behrens A, Iacovino M, Lohr J, Ren Y, Zierold C, Harvey R, et al. Nkx2-5 mediates differential cardiac differentiation through interaction with Hoxa10. Stem Cells Dev. 2013;22:2211-20 pubmed 出版商
  • 免疫细胞化学; 小鼠
Trakala M, Fernández Miranda G, Perez de Castro I, Heeschen C, Malumbres M. Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1). Cell Cycle. 2013;12:1030-41 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400
Imbalzano K, Cohet N, Wu Q, Underwood J, Imbalzano A, Nickerson J. Nuclear shape changes are induced by knockdown of the SWI/SNF ATPase BRG1 and are independent of cytoskeletal connections. PLoS ONE. 2013;8:e55628 pubmed 出版商
  • 免疫印迹; 大鼠; 1:10000
Taylor D, Moser R, Regulier E, Breuillaud L, Dixon M, Beesen A, et al. MAP kinase phosphatase 1 (MKP-1/DUSP1) is neuroprotective in Huntington's disease via additive effects of JNK and p38 inhibition. J Neurosci. 2013;33:2313-25 pubmed 出版商
  • 免疫细胞化学; 鸡; 1:2000
Wang Y, Dantas T, Lalor P, Dockery P, Morrison C. Promoter hijack reveals pericentrin functions in mitosis and the DNA damage response. Cell Cycle. 2013;12:635-46 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Carra E, Barbieri F, Marubbi D, Pattarozzi A, Favoni R, Florio T, et al. Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures. Cell Cycle. 2013;12:491-500 pubmed 出版商
  • 免疫细胞化学; 人类
Blakemore L, Boes C, Cordell R, Manson M. Curcumin-induced mitotic arrest is characterized by spindle abnormalities, defects in chromosomal congression and DNA damage. Carcinogenesis. 2013;34:351-60 pubmed 出版商
  • 免疫印迹; fission yeast
Limbo O, Moiani D, Kertokalio A, Wyman C, Tainer J, Russell P. Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair. Nucleic Acids Res. 2012;40:11435-49 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Spiller C, Feng C, Jackson A, Gillis A, Rolland A, Looijenga L, et al. Endogenous Nodal signaling regulates germ cell potency during mammalian testis development. Development. 2012;139:4123-32 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 2
Xiao Y, Karnati S, Qian G, Nenicu A, Fan W, Tchatalbachev S, et al. Cre-mediated stress affects sirtuin expression levels, peroxisome biogenesis and metabolism, antioxidant and proinflammatory signaling pathways. PLoS ONE. 2012;7:e41097 pubmed 出版商
  • 免疫印迹; 人类
Hsin I, Hsiao Y, Wu M, Jan M, Tang S, Lin Y, et al. Lipocalin 2, a new GADD153 target gene, as an apoptosis inducer of endoplasmic reticulum stress in lung cancer cells. Toxicol Appl Pharmacol. 2012;263:330-7 pubmed 出版商
  • 免疫沉淀; 小鼠
Chao H, Lai Y, Lu Y, Lin C, Mai W, Huang Y. NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3. Nucleic Acids Res. 2012;40:8484-98 pubmed
  • 免疫印迹; 人类
Ren G, Baritaki S, Marathe H, Feng J, Park S, Beach S, et al. Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer. Cancer Res. 2012;72:3091-104 pubmed 出版商
  • 免疫细胞化学; fruit fly
  • 免疫印迹; fruit fly
Mohd Sarip A, Lagarou A, Doyen C, van der Knaap J, Aslan U, Bezstarosti K, et al. Transcription-independent function of Polycomb group protein PSC in cell cycle control. Science. 2012;336:744-7 pubmed 出版商
  • 免疫印迹; 小鼠
Lamming D, Ye L, Katajisto P, Goncalves M, Saitoh M, Stevens D, et al. Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity. Science. 2012;335:1638-43 pubmed 出版商
  • 免疫印迹; 家羊
Chkourko H, Guerrero Serna G, Lin X, Darwish N, Pohlmann J, Cook K, et al. Remodeling of mechanical junctions and of microtubule-associated proteins accompany cardiac connexin43 lateralization. Heart Rhythm. 2012;9:1133-1140.e6 pubmed 出版商
  • 免疫印迹; fission yeast
Koch A, Rode H, Richters A, Rauh D, Hauf S. A chemical genetic approach for covalent inhibition of analogue-sensitive aurora kinase. ACS Chem Biol. 2012;7:723-31 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Macia A, Gallel P, Vaquero M, Gou Fabregas M, Santacana M, Maliszewska A, et al. Sprouty1 is a candidate tumor-suppressor gene in medullary thyroid carcinoma. Oncogene. 2012;31:3961-72 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图  6
Balsas P, Galán Malo P, Marzo I, Naval J. Bortezomib resistance in a myeloma cell line is associated to PSM?5 overexpression and polyploidy. Leuk Res. 2012;36:212-8 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000; 图 1
Li D, Shin J, Duan D. iNOS ablation does not improve specific force of the extensor digitorum longus muscle in dystrophin-deficient mdx4cv mice. PLoS ONE. 2011;6:e21618 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000
Nasonkin I, Lazo K, Hambright D, Brooks M, Fariss R, Swaroop A. Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina. J Comp Neurol. 2011;519:1914-30 pubmed 出版商
  • 免疫印迹; 人类
Tsaytler P, Harding H, Ron D, Bertolotti A. Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. Science. 2011;332:91-4 pubmed 出版商
  • 免疫印迹; 猕猴; 图 6
Boichuk S, Hu L, Hein J, Gjoerup O. Multiple DNA damage signaling and repair pathways deregulated by simian virus 40 large T antigen. J Virol. 2010;84:8007-20 pubmed 出版商
  • 免疫印迹; 人类
Kramer O, Knauer S, Greiner G, Jandt E, Reichardt S, Gührs K, et al. A phosphorylation-acetylation switch regulates STAT1 signaling. Genes Dev. 2009;23:223-35 pubmed 出版商
  • 免疫印迹; 人类
Pandithage R, Lilischkis R, Harting K, Wolf A, Jedamzik B, Lüscher Firzlaff J, et al. The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility. J Cell Biol. 2008;180:915-29 pubmed 出版商
  • 免疫印迹; 猕猴
Martin Latil S, Mousson L, Autret A, Colbere Garapin F, Blondel B. Bax is activated during rotavirus-induced apoptosis through the mitochondrial pathway. J Virol. 2007;81:4457-64 pubmed
Jiang Q, Zheng N, Bu L, Zhang X, Zhang X, Wu Y, et al. SPOP-mediated ubiquitination and degradation of PDK1 suppresses AKT kinase activity and oncogenic functions. Mol Cancer. 2021;20:100 pubmed 出版商
Gras S, Blasco A, Mòdol Caballero G, Tarabal O, Casanovas A, Piedrafita L, et al. Beneficial effects of dietary supplementation with green tea catechins and cocoa flavanols on aging-related regressive changes in the mouse neuromuscular system. Aging (Albany NY). 2021;13:18051-18093 pubmed 出版商
Jeong A, Cheng S, Zhong R, Bennett D, Bergo M, Li L. Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice. Acta Neuropathol Commun. 2021;9:129 pubmed 出版商
Wu T, Wang Y, Xiao T, Ai Y, Li J, Zeng Y, et al. Lentiviral CRISPR-guided RNA library screening identified Adam17 as an upstream negative regulator of Procr in mammary epithelium. BMC Biotechnol. 2021;21:42 pubmed 出版商
Chrysostomou S, Roy R, Prischi F, Thamlikitkul L, Chapman K, Mufti U, et al. Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer. Sci Transl Med. 2021;13: pubmed 出版商
Templehof H, Moshe N, Avraham Davidi I, Yaniv K. Zebrafish mutants provide insights into Apolipoprotein B functions during embryonic development and pathological conditions. JCI Insight. 2021;6: pubmed 出版商
Su S, Chen J, Jiang Y, Wang Y, Vital T, Zhang J, et al. SPOP and OTUD7A Control EWS-FLI1 Protein Stability to Govern Ewing Sarcoma Growth. Adv Sci (Weinh). 2021;8:e2004846 pubmed 出版商
Trimarco J, Heaton B, Chaparian R, Burke K, Binder R, Gray G, et al. TMEM41B is a host factor required for the replication of diverse coronaviruses including SARS-CoV-2. PLoS Pathog. 2021;17:e1009599 pubmed 出版商
Gómez Ferrer M, Villanueva Badenas E, Sánchez Sánchez R, Sánchez López C, Baquero M, Sepulveda P, et al. HIF-1α and Pro-Inflammatory Signaling Improves the Immunomodulatory Activity of MSC-Derived Extracellular Vesicles. Int J Mol Sci. 2021;22: pubmed 出版商
Boulanger A, Thinat C, Zuchner S, Fradkin L, Lortat Jacob H, Dura J. Axonal chemokine-like Orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling. Nat Commun. 2021;12:1849 pubmed 出版商
Nam D, Kim A, Han S, Lee S, Park S, Seol W, et al. Analysis of α-synuclein levels related to LRRK2 kinase activity: from substantia nigra to urine of patients with Parkinson's disease. Anim Cells Syst (Seoul). 2021;25:28-36 pubmed 出版商
Castro Córdova P, Mora Uribe P, Reyes Ramírez R, Cofre Araneda G, Orozco Aguilar J, Brito Silva C, et al. Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection. Nat Commun. 2021;12:1140 pubmed 出版商
Zhang Z, Luo S, Barbosa G, Bai M, Kornberg T, Ma D. The conserved transmembrane protein TMEM-39 coordinates with COPII to promote collagen secretion and regulate ER stress response. PLoS Genet. 2021;17:e1009317 pubmed 出版商
Zhou M, Kamarshi V, Arvin A, Oliver S. Calcineurin phosphatase activity regulates Varicella-Zoster Virus induced cell-cell fusion. PLoS Pathog. 2020;16:e1009022 pubmed 出版商
Hall Roberts H, Agarwal D, Obst J, Smith T, Monzón Sandoval J, Di Daniel E, et al. TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages. Alzheimers Res Ther. 2020;12:151 pubmed 出版商
Ramesh N, Daley E, Gleixner A, Mann J, Kour S, Mawrie D, et al. RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3. Acta Neuropathol Commun. 2020;8:177 pubmed 出版商
Lee H, Park J, Yoo H, Lee H, Lee B, Kim J. The Selenoprotein MsrB1 Instructs Dendritic Cells to Induce T-Helper 1 Immune Responses. Antioxidants (Basel). 2020;9: pubmed 出版商
Wu L, Huang B, Lai S, Lin C, Lin H, Yang L, et al. SIRT1 activation by minocycline on regulation of microglial polarization homeostasis. Aging (Albany NY). 2020;12:17990-18007 pubmed 出版商
Sá Pessoa J, Przybyszewska K, Vasconcelos F, Dumigan A, Frank C, Hobley L, et al. Klebsiella pneumoniae Reduces SUMOylation To Limit Host Defense Responses. MBio. 2020;11: pubmed 出版商
Garbett D, Bisaria A, Yang C, McCarthy D, Hayer A, Moerner W, et al. T-Plastin reinforces membrane protrusions to bridge matrix gaps during cell migration. Nat Commun. 2020;11:4818 pubmed 出版商
Chou C, Yang R, Chan L, Li C, Sun L, Lee H, et al. The stabilization of PD-L1 by the endoplasmic reticulum stress protein GRP78 in triple-negative breast cancer. Am J Cancer Res. 2020;10:2621-2634 pubmed
Ramesh N, Kour S, Anderson E, Rajasundaram D, Pandey U. RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM. Acta Neuropathol Commun. 2020;8:138 pubmed 出版商
Briese M, Saal Bauernschubert L, Lüningschrör P, Moradi M, Dombert B, Surrey V, et al. Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function. Acta Neuropathol Commun. 2020;8:116 pubmed 出版商
Han B, Seah M, Brooks I, Quek D, Huxley D, Foo C, et al. Global translation during early development depends on the essential transcription factor PRDM10. Nat Commun. 2020;11:3603 pubmed 出版商
Jin L, Zhao K, Xu L, Zhao R, Werle K, Wang Y, et al. LKB1 inactivation leads to centromere defects and genome instability via p53-dependent upregulation of survivin. Aging (Albany NY). 2020;12:14341-14354 pubmed 出版商
Yan P, Patel H, Sharma S, Corben A, Wang T, Panchal P, et al. Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone. Cell Rep. 2020;31:107840 pubmed 出版商
Sobral L, Sechler M, Parrish J, McCann T, Jones K, Black J, et al. KDM3A/Ets1/MCAM axis promotes growth and metastatic properties in Rhabdomyosarcoma. Genes Cancer. 2020;11:53-65 pubmed 出版商
Do M, Lee J, Ahn J, Hong M, Kim J, Kim S. Isosamidin from Peucedanum japonicum Roots Prevents Methylglyoxal-Induced Glucotoxicity in Human Umbilical Vein Endothelial Cells via Suppression of ROS-Mediated Bax/Bcl-2. Antioxidants (Basel). 2020;9: pubmed 出版商
Schnormeier A, Pommerenke C, Kaufmann M, Drexler H, Koeppel M. Genomic deregulation of PRMT5 supports growth and stress tolerance in chronic lymphocytic leukemia. Sci Rep. 2020;10:9775 pubmed 出版商
Bobkov G, Huang A, van den Berg S, Mitra S, Anselm E, Lazou V, et al. Spt6 is a maintenance factor for centromeric CENP-A. Nat Commun. 2020;11:2919 pubmed 出版商
Hoxha S, Shepard A, Troutman S, Diao H, Doherty J, Janiszewska M, et al. YAP-Mediated Recruitment of YY1 and EZH2 Represses Transcription of Key Cell-Cycle Regulators. Cancer Res. 2020;80:2512-2522 pubmed 出版商
Williams G, Gokhale N, Snider D, Horner S. The mRNA Cap 2'-O-Methyltransferase CMTR1 Regulates the Expression of Certain Interferon-Stimulated Genes. mSphere. 2020;5: pubmed 出版商
Lima N, Atkinson E, Bunney T, Katan M, Huang P. Targeting the Src Pathway Enhances the Efficacy of Selective FGFR Inhibitors in Urothelial Cancers with FGFR3 Alterations. Int J Mol Sci. 2020;21: pubmed 出版商
Wu X, Gardashova G, Lan L, Han S, Zhong C, Marquez R, et al. Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis. Commun Biol. 2020;3:193 pubmed 出版商
Hartmann C, Schwietzer Y, Kummer D, Kirschnick N, Hoppe E, Thüring E, et al. The mitochondrial outer membrane protein SYNJ2BP interacts with the cell adhesion molecule TMIGD1 and can recruit it to mitochondria. BMC Mol Cell Biol. 2020;21:30 pubmed 出版商
Hoevenaar W, Janssen A, Quirindongo A, Ma H, Klaasen S, Teixeira A, et al. Degree and site of chromosomal instability define its oncogenic potential. Nat Commun. 2020;11:1501 pubmed 出版商
Hölper J, Klupp B, Luxton G, Franzke K, Mettenleiter T. Function of Torsin AAA+ ATPases in Pseudorabies Virus Nuclear Egress. Cells. 2020;9: pubmed 出版商
Chan A, Huber A, Lamia K. Cryptochromes modulate E2F family transcription factors. Sci Rep. 2020;10:4077 pubmed 出版商
Barroso Vilares M, Macedo J, Reis M, Warren J, Compton D, Logarinho E. Small-molecule inhibition of aging-associated chromosomal instability delays cellular senescence. EMBO Rep. 2020;21:e49248 pubmed 出版商
Liu J, Chen H, Ma L, He Z, Wang D, Liu Y, et al. Light-induced control of protein destruction by opto-PROTAC. Sci Adv. 2020;6:eaay5154 pubmed 出版商
Zhang Z, Bai M, Barbosa G, Chen A, Wei Y, Luo S, et al. Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking. Sci Adv. 2020;6:eaay7667 pubmed 出版商
Cao Y, Lipka J, Stucchi R, Burute M, Pan X, Portegies S, et al. Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization. Curr Biol. 2020;30:899-908.e6 pubmed 出版商
Luciani A, Schumann A, Berquez M, Chen Z, Nieri D, Failli M, et al. Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nat Commun. 2020;11:970 pubmed 出版商
Epstein Shochet G, Brook E, Bardenstein Wald B, Shitrit D. TGF-β pathway activation by idiopathic pulmonary fibrosis (IPF) fibroblast derived soluble factors is mediated by IL-6 trans-signaling. Respir Res. 2020;21:56 pubmed 出版商
Du M, Wang G, Barsukov I, Gross S, Smith R, Rudland P. Direct interaction of metastasis-inducing S100P protein with tubulin causes enhanced cell migration without changes in cell adhesion. Biochem J. 2020;477:1159-1178 pubmed 出版商
Oh L, Hainaut P, Blanchet S, Ariffin H. Expression of p53 N-terminal isoforms in B-cell precursor acute lymphoblastic leukemia and its correlation with clinicopathological profiles. BMC Cancer. 2020;20:110 pubmed 出版商
Yu L, Kim J, Jiang L, Feng B, Ying Y, Ji K, et al. MTR4 drives liver tumorigenesis by promoting cancer metabolic switch through alternative splicing. Nat Commun. 2020;11:708 pubmed 出版商
Mejhert N, Kuruvilla L, Gabriel K, Elliott S, Guie M, Wang H, et al. Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression. Mol Cell. 2020;77:1251-1264.e9 pubmed 出版商
Tian W, Czopka T, Lopez Schier H. Systemic loss of Sarm1 protects Schwann cells from chemotoxicity by delaying axon degeneration. Commun Biol. 2020;3:49 pubmed 出版商
Chew N, Nguyen E, Su S, Novy K, Chan H, Nguyen L, et al. FGFR3 signaling and function in triple negative breast cancer. Cell Commun Signal. 2020;18:13 pubmed 出版商
Lee J, Subedi L, Kim S. Effect of Cysteine on Methylglyoxal-Induced Renal Damage in Mesangial Cells. Cells. 2020;9: pubmed 出版商
Bersini S, Lytle N, Schulte R, Huang L, Wahl G, Hetzer M. Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling. Life Sci Alliance. 2020;3: pubmed 出版商
Mzoughi S, Di Tullio F, Low D, Motofeanu C, Ong S, Wollmann H, et al. PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly. Sci Adv. 2020;6:eaax9852 pubmed 出版商
Giró Perafita A, Luo L, Khodadadi Jamayran A, Thompson M, Akgöl Oksuz B, Tsirigos A, et al. LncRNA RP11-19E11 is an E2F1 target required for proliferation and survival of basal breast cancer. NPJ Breast Cancer. 2020;6:1 pubmed 出版商
Kim M, Sujkowski A, Namkoong S, Gu B, Cobb T, Kim B, et al. Sestrins are evolutionarily conserved mediators of exercise benefits. Nat Commun. 2020;11:190 pubmed 出版商
Lee E, Choi A, Jun Y, Kim N, Yook J, Kim S, et al. Glutathione peroxidase-1 regulates adhesion and metastasis of triple-negative breast cancer cells via FAK signaling. Redox Biol. 2020;29:101391 pubmed 出版商
Zhang Y, Schroeder L, Lessard M, Kidd P, Chung J, Song Y, et al. Nanoscale subcellular architecture revealed by multicolor three-dimensional salvaged fluorescence imaging. Nat Methods. 2020;17:225-231 pubmed 出版商
Li Y, Haarhuis J, Cacciatore Á, Oldenkamp R, van Ruiten M, Willems L, et al. The structural basis for cohesin-CTCF-anchored loops. Nature. 2020;: pubmed 出版商
Kronschnabl P, Grünweller A, Hartmann R, Aigner A, Weirauch U. Inhibition of PIM2 in liver cancer decreases tumor cell proliferation in vitro and in vivo primarily through the modulation of cell cycle progression. Int J Oncol. 2020;56:448-459 pubmed 出版商
Trötschel C, Hamzeh H, Alvarez L, Pascal R, Lavryk F, Bönigk W, et al. Absolute proteomic quantification reveals design principles of sperm flagellar chemosensation. EMBO J. 2020;39:e102723 pubmed 出版商
Jang H, Park S, Kim J, Kim J, Kim S, Cho S, et al. The Tumor Suppressor, p53, Negatively Regulates Non-Canonical NF-κB Signaling through miRNAInduced Silencing of NF-κB-Inducing Kinase. Mol Cells. 2020;43:23-33 pubmed 出版商
Oberhauser L, Granziera S, Colom A, Goujon A, Lavallard V, Matile S, et al. Palmitate and oleate modify membrane fluidity and kinase activities of INS-1E β-cells alongside altered metabolism-secretion coupling. Biochim Biophys Acta Mol Cell Res. 2020;1867:118619 pubmed 出版商
Lee J, Kim D, Griffin P, Sheehan P, Kim D, Musiek E, et al. Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer's disease. Aging Cell. 2020;19:e13078 pubmed 出版商
Chinen T, Yamamoto S, Takeda Y, Watanabe K, Kuroki K, Hashimoto K, et al. NuMA assemblies organize microtubule asters to establish spindle bipolarity in acentrosomal human cells. EMBO J. 2020;39:e102378 pubmed 出版商
Kueh A, Eccles S, Tang L, Garnham A, May R, Herold M, et al. HBO1 (KAT7) Does Not Have an Essential Role in Cell Proliferation, DNA Replication, or Histone 4 Acetylation in Human Cells. Mol Cell Biol. 2020;40: pubmed 出版商
Egusquiaguirre S, Liu S, Tošić I, Jiang K, Walker S, Nicolais M, et al. CDK5RAP3 is a co-factor for the oncogenic transcription factor STAT3. Neoplasia. 2020;22:47-59 pubmed 出版商
Saila S, Gyanwali G, Hussain M, Gianfelice A, Ireton K. The Host GTPase Arf1 and Its Effectors AP1 and PICK1 Stimulate Actin Polymerization and Exocytosis To Promote Entry of Listeria monocytogenes. Infect Immun. 2020;88: pubmed 出版商
Guarascio R, Salih D, Yasvoina M, Edwards F, Cheetham M, van der Spuy J. Negative Regulator of Ubiquitin-Like Protein 1 modulates the autophagy-lysosomal pathway via p62 to facilitate the extracellular release of tau following proteasome impairment. Hum Mol Genet. 2020;29:80-96 pubmed 出版商
Viau A, Kotsis F, Boehlke C, Braeg S, Klein M, Nitschke R, et al. Divergent function of polycystin 1 and polycystin 2 in cell size regulation. Biochem Biophys Res Commun. 2020;521:290-295 pubmed 出版商
Nihei Y, Mori K, Werner G, Arzberger T, Zhou Q, Khosravi B, et al. Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3. Acta Neuropathol. 2020;139:99-118 pubmed 出版商
Sjölander J, Sunnerhagen P. The fission yeast FHIT homolog affects checkpoint control of proliferation and is regulated by mitochondrial electron transport. Cell Biol Int. 2020;44:412-423 pubmed 出版商
Duquette P, Lamarche Vane N. The calcium-activated protease calpain regulates netrin-1 receptor deleted in colorectal cancer-induced axon outgrowth in cortical neurons. J Neurochem. 2020;152:315-332 pubmed 出版商
Grasso S, Cangelosi D, Chapelle J, Alzona M, Centonze G, Lamolinara A, et al. The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma. Cell Death Differ. 2020;27:790-807 pubmed 出版商
Balli M, Chui J, Athanasouli P, Abreu de Oliveira W, El Laithy Y, Sampaolesi M, et al. Activator Protein-1 Transcriptional Activity Drives Soluble Micrograft-Mediated Cell Migration and Promotes the Matrix Remodeling Machinery. Stem Cells Int. 2019;2019:6461580 pubmed 出版商
Morshneva A, Gnedina O, Marusova T, Igotti M. Expression of Adenoviral E1A in Transformed Cells as an Additional Factor of HDACi-Dependent FoxO Regulation. Cells. 2019;9: pubmed 出版商
Yang C, Kato H, Shindo M, Masai H. Cdc7 activates replication checkpoint by phosphorylating the Chk1-binding domain of Claspin in human cells. elife. 2019;8: pubmed 出版商
Ma Q, Wu K, Li H, Li H, Zhu Y, Hu G, et al. ONECUT2 overexpression promotes RAS-driven lung adenocarcinoma progression. Sci Rep. 2019;9:20021 pubmed 出版商
Park H, Helfman D. Up-regulated fibronectin in 3D culture facilitates spreading of triple negative breast cancer cells on 2D through integrin β-5 and Src. Sci Rep. 2019;9:19950 pubmed 出版商
Rossi F, Helbling Leclerc A, Kawasumi R, Jegadesan N, Xu X, Devulder P, et al. SMC5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability. EMBO Rep. 2019;:e48222 pubmed 出版商
Stevens A, Xiang M, Heppler L, Tošić I, Jiang K, Munoz J, et al. Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation. Blood Adv. 2019;3:4215-4227 pubmed 出版商
Bell E, Coelho P, Ratcliffe C, Rajadurai C, Peschard P, Vaillancourt R, et al. LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion. Cell Rep. 2019;29:4053-4068.e6 pubmed 出版商
Heinonen T, Ciarlo E, Rigoni E, Regina J, Le Roy D, Roger T. Dual Deletion of the Sirtuins SIRT2 and SIRT3 Impacts on Metabolism and Inflammatory Responses of Macrophages and Protects From Endotoxemia. Front Immunol. 2019;10:2713 pubmed 出版商
Ujihara Y, Kanagawa M, Mohri S, Takatsu S, Kobayashi K, Toda T, et al. Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associated heart failure. Nat Commun. 2019;10:5754 pubmed 出版商
Li X, Itani O, Haataja L, Dumas K, Yang J, Cha J, et al. Requirement for translocon-associated protein (TRAP) α in insulin biogenesis. Sci Adv. 2019;5:eaax0292 pubmed 出版商
Zhou J, Xue Z, He H, Liu X, Yin S, Wu D, et al. Resveratrol delays postovulatory aging of mouse oocytes through activating mitophagy. Aging (Albany NY). 2019;11:11504-11519 pubmed 出版商
Wu J, Tang Y, Zhang C. Targeting N-Terminal Huntingtin with a Dual-sgRNA Strategy by CRISPR/Cas9. Biomed Res Int. 2019;2019:1039623 pubmed 出版商
Llorens M, Rossi F, García I, Cooke M, Abba M, Lopez Haber C, et al. PKCα Modulates Epithelial-to-Mesenchymal Transition and Invasiveness of Breast Cancer Cells Through ZEB1. Front Oncol. 2019;9:1323 pubmed 出版商
Francisco Fernandez M, Charfi C, Piloto Ferrer J, Lidia González M, Lamy S, Annabi B. Targeting Ovarian Cancer Cell Cytotoxic Drug Resistance Phenotype with Xanthium strumarium L. Extract. Evid Based Complement Alternat Med. 2019;2019:6073019 pubmed 出版商
Bjørlykke Y, Søviknes A, Hoareau L, Vethe H, Mathisen A, Chera S, et al. Reprogrammed Cells Display Distinct Proteomic Signatures Associated with Colony Morphology Variability. Stem Cells Int. 2019;2019:8036035 pubmed 出版商
Aguanno S, Petrelli C, Di Siena S, De Angelis L, Pellegrini M, Naro F. A Three-Dimensional Culture Model of Reversibly Quiescent Myogenic Cells. Stem Cells Int. 2019;2019:7548160 pubmed 出版商
Hong S, Yi J, Lee S, Park C, Ryu J, Shin K, et al. Defective neurogenesis and schizophrenia-like behavior in PARP-1-deficient mice. Cell Death Dis. 2019;10:943 pubmed 出版商
Ranjbar S, Haridas V, Nambu A, Jasenosky L, Sadhukhan S, Ebert T, et al. Cytoplasmic RNA Sensor Pathways and Nitazoxanide Broadly Inhibit Intracellular Mycobacterium tuberculosis Growth. iScience. 2019;22:299-313 pubmed 出版商
Ysselstein D, Nguyen M, Young T, Severino A, Schwake M, Merchant K, et al. LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson's disease patients. Nat Commun. 2019;10:5570 pubmed 出版商
Po A, Giuliani A, Masiello M, Cucina A, Catizone A, Ricci G, et al. Phenotypic transitions enacted by simulated microgravity do not alter coherence in gene transcription profile. NPJ Microgravity. 2019;5:27 pubmed 出版商
Tonazzini I, van Woerden G, Masciullo C, Mientjes E, Elgersma Y, Cecchini M. The role of ubiquitin ligase E3A in polarized contact guidance and rescue strategies in UBE3A-deficient hippocampal neurons. Mol Autism. 2019;10:41 pubmed 出版商
Weber S, Koschade S, Hoffmann C, Dubash T, Giessler K, Dieter S, et al. The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo. BMC Cancer. 2019;19:1181 pubmed 出版商
Díaz López I, Toribio R, Berlanga J, Ventoso I. An mRNA-binding channel in the ES6S region of the translation 48S-PIC promotes RNA unwinding and scanning. elife. 2019;8: pubmed 出版商
Li Z, Chen B, Dong W, Kong M, Fan Z, Yu L, et al. MKL1 promotes endothelial-to-mesenchymal transition and liver fibrosis by activating TWIST1 transcription. Cell Death Dis. 2019;10:899 pubmed 出版商
Ruiz M, Bodhicharla R, Ståhlman M, Svensk E, Busayavalasa K, Palmgren H, et al. Evolutionarily conserved long-chain Acyl-CoA synthetases regulate membrane composition and fluidity. elife. 2019;8: pubmed 出版商
Costales Carrera A, Fernández Barral A, Bustamante Madrid P, Guerra L, Cantero R, Barbachano A, et al. Plocabulin Displays Strong Cytotoxic Activity in a Personalized Colon Cancer Patient-Derived 3D Organoid Assay. Mar Drugs. 2019;17: pubmed 出版商
Martin Rincon M, Pérez López A, Morales Alamo D, Perez Suarez I, de Pablos Velasco P, Perez Valera M, et al. Exercise Mitigates the Loss of Muscle Mass by Attenuating the Activation of Autophagy during Severe Energy Deficit. Nutrients. 2019;11: pubmed 出版商
Barthem C, Rossetti C, Carvalho D, da Silva W. Metformin ameliorates body mass gain and early metabolic changes in ovariectomized rats. Endocr Connect. 2019;8:1568-1578 pubmed 出版商
Iodice G, Perinetti G, Ludwig B, Polishchuk E, Polishchuk R. Biological Effects of Anodic Oxidation on Titanium Miniscrews: An In Vitro Study on Human Cells. Dent J (Basel). 2019;7: pubmed 出版商
Aguado J, Sola Carvajal A, Cancila V, Revêchon G, Ong P, Jones Weinert C, et al. Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson-Gilford Progeria Syndrome. Nat Commun. 2019;10:4990 pubmed 出版商
Howles S, Wiberg A, Goldsworthy M, Bayliss A, Gluck A, Ng M, et al. Genetic variants of calcium and vitamin D metabolism in kidney stone disease. Nat Commun. 2019;10:5175 pubmed 出版商
Oser M, Sabet A, Gao W, Chakraborty A, Schinzel A, Jennings R, et al. The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis. Genes Dev. 2019;33:1718-1738 pubmed 出版商
Sun B, Chang H, Salinger A, Tomita B, Bawadekar M, Holmes C, et al. Reciprocal regulation of Th2 and Th17 cells by PAD2-mediated citrullination. JCI Insight. 2019;4: pubmed 出版商
Yifa O, Weisinger K, Bassat E, Li H, Kain D, Barr H, et al. The small molecule Chicago Sky Blue promotes heart repair following myocardial infarction in mice. JCI Insight. 2019;4: pubmed 出版商
Hossain M, Larrous F, Rawlinson S, Zhan J, Sethi A, Ibrahim Y, et al. Structural Elucidation of Viral Antagonism of Innate Immunity at the STAT1 Interface. Cell Rep. 2019;29:1934-1945.e8 pubmed 出版商
Chung J, Wu X, Lambert T, Lai Z, Walther T, Farese R. LDAF1 and Seipin Form a Lipid Droplet Assembly Complex. Dev Cell. 2019;51:551-563.e7 pubmed 出版商
Grimaldi G, Vagaska B, Ievglevskyi O, Kondratskaya E, Glover J, Matthews J. Loss of Tiparp Results in Aberrant Layering of the Cerebral Cortex. Eneuro. 2019;6: pubmed 出版商
Feng F, Sun J, Radhakrishnan G, Lee T, Bozsoki Z, Fort S, et al. A combination of chitooligosaccharide and lipochitooligosaccharide recognition promotes arbuscular mycorrhizal associations in Medicago truncatula. Nat Commun. 2019;10:5047 pubmed 出版商
Hori A, Nishide K, Yasukuni Y, Haga K, Kakuta W, Ishikawa Y, et al. Prominin-1 Modulates Rho/ROCK-Mediated Membrane Morphology and Calcium-Dependent Intracellular Chloride Flux. Sci Rep. 2019;9:15911 pubmed 出版商
Rattila S, Dunk C, Im M, Grichenko O, Zhou Y, Yanez Mo M, et al. Interaction of Pregnancy-Specific Glycoprotein 1 With Integrin Α5β1 Is a Modulator of Extravillous Trophoblast Functions. Cells. 2019;8: pubmed 出版商
Ide M, Ohnishi T, Toyoshima M, Balan S, Maekawa M, Shimamoto Mitsuyama C, et al. Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology. EMBO Mol Med. 2019;11:e10695 pubmed 出版商
Pergolizzi B, Panuzzo C, Ali M, Lo Iacono M, Levra Levron C, Ponzone L, et al. Two conserved glycine residues in mammalian and Dictyostelium Rictor are required for mTORC2 activity and integrity. J Cell Sci. 2019;132: pubmed 出版商
Yoo T, Cho H, Park H, Lee J, Kim E. Shank3 Exons 14-16 Deletion in Glutamatergic Neurons Leads to Social and Repetitive Behavioral Deficits Associated With Increased Cortical Layer 2/3 Neuronal Excitability. Front Cell Neurosci. 2019;13:458 pubmed 出版商
Zhou Y, Wang X, Song M, He Z, Cui G, Peng G, et al. A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing. Nat Commun. 2019;10:4827 pubmed 出版商
Di Maira G, Gentilini A, Pastore M, Caligiuri A, Piombanti B, Raggi C, et al. The protein kinase CK2 contributes to the malignant phenotype of cholangiocarcinoma cells. Oncogenesis. 2019;8:61 pubmed 出版商
Hildebrandt A, Brüggemann M, Rücklé C, Boerner S, Heidelberger J, Busch A, et al. The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation. Genome Biol. 2019;20:216 pubmed 出版商
Alijagic A, Benada O, Kofronova O, Cigna D, Pinsino A. Sea Urchin Extracellular Proteins Design a Complex Protein Corona on Titanium Dioxide Nanoparticle Surface Influencing Immune Cell Behavior. Front Immunol. 2019;10:2261 pubmed 出版商
Shi Y, Manis M, Long J, Wang K, Sullivan P, Remolina Serrano J, et al. Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model. J Exp Med. 2019;216:2546-2561 pubmed 出版商
Papini D, Fant X, Ogawa H, Desban N, Samejima K, Feizbakhsh O, et al. Cell cycle-independent furrowing triggered by phosphomimetic mutations of the INCENP STD motif requires Plk1. J Cell Sci. 2019;132: pubmed 出版商
Rivière L, Quioc Salomon B, Fallot G, Halgand B, Feray C, Buendia M, et al. Hepatitis B virus replicating in hepatocellular carcinoma encodes HBx variants with preserved ability to antagonize restriction by Smc5/6. Antiviral Res. 2019;172:104618 pubmed 出版商
Buchwalter A, Schulte R, Tsai H, Capitanio J, Hetzer M. Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress. elife. 2019;8: pubmed 出版商
Lewis C, Bukhari A, Xiao E, Choi W, Smith J, Homola E, et al. Upregulation of Myt1 Promotes Acquired Resistance of Cancer Cells to Wee1 Inhibition. Cancer Res. 2019;79:5971-5985 pubmed 出版商
Orejudo M, Rodrigues Díez R, Rodrígues Díez R, García Redondo A, Santos Sánchez L, Rández Garbayo J, et al. Interleukin 17A Participates in Renal Inflammation Associated to Experimental and Human Hypertension. Front Pharmacol. 2019;10:1015 pubmed 出版商
Han D, Schomacher L, Schüle K, Mallick M, Musheev M, Karaulanov E, et al. NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress. elife. 2019;8: pubmed 出版商
Wu Y, Ding Y, Zheng X, Liao K. The molecular chaperone Hsp90 maintains Golgi organization and vesicular trafficking by regulating microtubule stability. J Mol Cell Biol. 2019;: pubmed 出版商
Laurin M, Gomez N, Levorse J, Sendoel A, Sribour M, Fuchs E. An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis. elife. 2019;8: pubmed 出版商
Pérez González C, Alert R, Blanch Mercader C, Gómez González M, Kolodziej T, Bazellieres E, et al. Active wetting of epithelial tissues. Nat Phys. 2019;15:79-88 pubmed 出版商
Gentsch G, Spruce T, Owens N, Smith J. Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals. Nat Commun. 2019;10:4269 pubmed 出版商
Huang A, Kremser L, Schüler F, Wilflingseder D, Lindner H, Geley S, et al. Phosphorylation of Drosophila CENP-A on serine 20 regulates protein turn-over and centromere-specific loading. Nucleic Acids Res. 2019;47:10754-10770 pubmed 出版商
CHENG A, Moraes S, Attarian C, Yockteng Melgar J, Jarvis M, Biolatti M, et al. A Conserved Mechanism of APOBEC3 Relocalization by Herpesviral Ribonucleotide Reductase Large Subunits. J Virol. 2019;93: pubmed 出版商
Cristini A, Ricci G, Britton S, Salimbeni S, Huang S, Marinello J, et al. Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks. Cell Rep. 2019;28:3167-3181.e6 pubmed 出版商
Lima Y, Kurauti M, da Fonseca Alves G, Ferezini J, Piovan S, Malta A, et al. Whey protein sweetened with Stevia rebaudiana Bertoni (Bert.) increases mitochondrial biogenesis markers in the skeletal muscle of resistance-trained rats. Nutr Metab (Lond). 2019;16:65 pubmed 出版商
Narula A, Ellis J, Taliaferro J, Rissland O. Coding regions affect mRNA stability in human cells. RNA. 2019;25:1751-1764 pubmed 出版商
Sawayama T, Nakashima K, Ichimura T, Sakai R, Uekita T. Homophilic complex formation of CDCP1 via the extracellular CUB2 domain facilitates SFK activation and promotes cancer cell migration. Oncol Rep. 2019;: pubmed 出版商
Dong Z, Jiang H, Liang S, Wang Y, Jiang W, Zhu C. Ribosomal Protein L15 is involved in Colon Carcinogenesis. Int J Med Sci. 2019;16:1132-1141 pubmed 出版商
Hoffman H, Fernandez M, Groves N, Freed E, Van Engelenburg S. Genomic tagging of endogenous human ESCRT-I complex preserves ESCRT-mediated membrane-remodeling functions. J Biol Chem. 2019;294:16266-16281 pubmed 出版商
Nousch M, Yeroslaviz A, Eckmann C. Stage-specific combinations of opposing poly(A) modifying enzymes guide gene expression during early oogenesis. Nucleic Acids Res. 2019;47:10881-10893 pubmed 出版商
Lombard A, Liu C, Armstrong C, D Abronzo L, Lou W, Evans C, et al. Wntless promotes cellular viability and resistance to enzalutamide in castration-resistant prostate cancer cells. Am J Clin Exp Urol. 2019;7:203-214 pubmed
Jeru I, Vantyghem M, Bismuth E, Cervera P, Barraud S, Auclair M, et al. Diagnostic Challenge in PLIN1-Associated Familial Partial Lipodystrophy. J Clin Endocrinol Metab. 2019;104:6025-6032 pubmed 出版商
Ravikumar S, Devanapally S, Jose A. Gene silencing by double-stranded RNA from C. elegans neurons reveals functional mosaicism of RNA interference. Nucleic Acids Res. 2019;47:10059-10071 pubmed 出版商
Liu X, Jiang Y, Takata K, Nowak B, Liu C, Wood R, et al. CNDAC-Induced DNA Double-Strand Breaks Cause Aberrant Mitosis Prior to Cell Death. Mol Cancer Ther. 2019;18:2283-2295 pubmed 出版商
Seoane Collazo P, Liñares Pose L, Rial Pensado E, Romero Picó A, Moreno Navarrete J, Martínez Sánchez N, et al. Central nicotine induces browning through hypothalamic κ opioid receptor. Nat Commun. 2019;10:4037 pubmed 出版商
Asperti M, Cantamessa L, Ghidinelli S, Gryzik M, Denardo A, Giacomini A, et al. The Antitumor Didox Acts as an Iron Chelator in Hepatocellular Carcinoma Cells. Pharmaceuticals (Basel). 2019;12: pubmed 出版商
Liang X, Arullampalam P, Yang Z, Ming X. Hypoxia Enhances Endothelial Intercellular Adhesion Molecule 1 Protein Level Through Upregulation of Arginase Type II and Mitochondrial Oxidative Stress. Front Physiol. 2019;10:1003 pubmed 出版商
Tapia R, Pérez Yépez E, Carlino M, Karandikar U, Kralicek S, Estes M, et al. Sperm Flagellar 1 Binds Actin in Intestinal Epithelial Cells and Contributes to Formation of Filopodia and Lamellipodia. Gastroenterology. 2019;157:1544-1555.e3 pubmed 出版商
Oya E, Nakagawa R, Yoshimura Y, Tanaka M, Nishibuchi G, Machida S, et al. H3K14 ubiquitylation promotes H3K9 methylation for heterochromatin assembly. EMBO Rep. 2019;20:e48111 pubmed 出版商
Lee G, Chang C, Chiu W, Hsiao T, Chen P, Wang K, et al. A thrombomodulin-like gene is crucial to the collective migration of epibolic blastomeres during germ layer formation and organogenesis in zebrafish. J Biomed Sci. 2019;26:60 pubmed 出版商
Alptekin A, Ye B, Yu Y, Poole C, van Riggelen J, Zha Y, et al. Glycine decarboxylase is a transcriptional target of MYCN required for neuroblastoma cell proliferation and tumorigenicity. Oncogene. 2019;38:7504-7520 pubmed 出版商
Li J, Ye J, Zhu S, Cui H. Down-Regulation of Phosphoribosyl Pyrophosphate Synthetase 1 Inhibits Neuroblastoma Cell Proliferation. Cells. 2019;8: pubmed 出版商
Lindhout F, Cao Y, Kevenaar J, Bodzęta A, Stucchi R, Boumpoutsari M, et al. VAP-SCRN1 interaction regulates dynamic endoplasmic reticulum remodeling and presynaptic function. EMBO J. 2019;:e101345 pubmed 出版商
Sonthonnax F, Besson B, Bonnaud E, Jouvion G, Merino D, Larrous F, et al. Lyssavirus matrix protein cooperates with phosphoprotein to modulate the Jak-Stat pathway. Sci Rep. 2019;9:12171 pubmed 出版商
Lee C, Li M, Feke A, Liu W, Saffer A, Gendron J. GIGANTEA recruits the UBP12 and UBP13 deubiquitylases to regulate accumulation of the ZTL photoreceptor complex. Nat Commun. 2019;10:3750 pubmed 出版商
Yang Y, Willis T, Button R, Strang C, Fu Y, Wen X, et al. Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response. Nat Commun. 2019;10:3759 pubmed 出版商
Contreras O, Cruz Soca M, Theret M, Soliman H, Tung L, Groppa E, et al. Cross-talk between TGF-β and PDGFRα signaling pathways regulates the fate of stromal fibro-adipogenic progenitors. J Cell Sci. 2019;132: pubmed 出版商
Andreadis C, Hulme L, Wensley K, Liu J. The TOR pathway modulates cytoophidium formation in Schizosaccharomyces pombe. J Biol Chem. 2019;294:14686-14703 pubmed 出版商
Buenaventura T, Bitsi S, Laughlin W, Burgoyne T, Lyu Z, Oqua A, et al. Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells. PLoS Biol. 2019;17:e3000097 pubmed 出版商
Sánchez Fernández E, García Moreno M, Arroba A, Aguilar Diosdado M, Padron J, García Hernández R, et al. Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and anti-inflammatory therapies. Eur J Med Chem. 2019;182:111604 pubmed 出版商
Coates H, Chua N, Brown A. Consulting prostate cancer cohort data uncovers transcriptional control: Regulation of the MARCH6 gene. Biochim Biophys Acta Mol Cell Biol Lipids. 2019;1864:1656-1668 pubmed 出版商
Liu L, Lauro B, Ding L, Rovere M, Wolfe M, Selkoe D. Multiple BACE1 inhibitors abnormally increase the BACE1 protein level in neurons by prolonging its half-life. Alzheimers Dement. 2019;15:1183-1194 pubmed 出版商
Dutta P, Islam S, Choppara S, Sengupta P, Kumar A, Kumar A, et al. The tumor suppressor FBXO31 preserves genomic integrity by regulating DNA replication and segregation through precise control of cyclin A levels. J Biol Chem. 2019;294:14879-14895 pubmed 出版商
Tang Z, Takahashi Y, He H, Hattori T, Chen C, Liang X, et al. TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion. Cell Rep. 2019;28:1744-1757.e5 pubmed 出版商
Danet L, Beauclair G, Berthet M, Moratorio G, Gracias S, Tangy F, et al. Midgut barriers prevent the replication and dissemination of the yellow fever vaccine in Aedes aegypti. PLoS Negl Trop Dis. 2019;13:e0007299 pubmed 出版商
Jacomin A, Geraki K, Brooks J, Tjendana Tjhin V, Collingwood J, Nezis I. Impact of Autophagy and Aging on Iron Load and Ferritin in Drosophila Brain. Front Cell Dev Biol. 2019;7:142 pubmed 出版商
Jasenosky L, Cadena C, Mire C, Borisevich V, Haridas V, Ranjbar S, et al. The FDA-Approved Oral Drug Nitazoxanide Amplifies Host Antiviral Responses and Inhibits Ebola Virus. iScience. 2019;19:1279-1290 pubmed 出版商
Chen H, Moreno Moral A, Pesce F, Devapragash N, Mancini M, Heng E, et al. WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling. Nat Commun. 2019;10:3616 pubmed 出版商
Zhang R, Kan J, Lu S, Tong P, Yang J, Xi L, et al. S100A16-induced adipogenesis is associated with up-regulation of 11 β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). Biosci Rep. 2019;39: pubmed 出版商
Plissonnier M, Cottarel J, Piver E, Kullolli M, Centonze F, Pitteri S, et al. LARP1 binding to hepatitis C virus particles is correlated with intracellular retention of viral infectivity. Virus Res. 2019;271:197679 pubmed 出版商
Lu H, Saha J, Beckmann P, Hendrickson E, Davis A. DNA-PKcs promotes chromatin decondensation to facilitate initiation of the DNA damage response. Nucleic Acids Res. 2019;47:9467-9479 pubmed 出版商
Mennie A, Moser B, Hoyle A, Low R, Tanaka K, Nakamura T. Tpz1TPP1 prevents telomerase activation and protects telomeres by modulating the Stn1-Ten1 complex in fission yeast. Commun Biol. 2019;2:297 pubmed 出版商
Méndez Barbero N, Gutiérrez Muñoz C, Madrigal Matute J, Minguez P, Egido J, Michel J, et al. A major role of TWEAK/Fn14 axis as a therapeutic target for post-angioplasty restenosis. EBioMedicine. 2019;46:274-289 pubmed 出版商
Chen C, Rodriguez Pino M, Haller P, Verde F. Conserved NDR/LATS kinase controls RAS GTPase activity to regulate cell growth and chronological lifespan. Mol Biol Cell. 2019;30:2598-2616 pubmed 出版商
Zhu W, Li J, Zhang R, Cai Y, Wang C, Qi S, et al. TRAF3IP3 mediates the recruitment of TRAF3 to MAVS for antiviral innate immunity. EMBO J. 2019;:e102075 pubmed 出版商
Jiang C, Trudeau S, Cheong T, Guo R, Teng M, Wang L, et al. CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation. Cell Rep. 2019;28:1307-1322.e8 pubmed 出版商
Li B, Gao Z, Liu X, Sun D, Tang W. Transcriptional Profiling Reveals a Time-of-Day-Specific Role of REVEILLE 4/8 in Regulating the First Wave of Heat Shock-Induced Gene Expression in Arabidopsis. Plant Cell. 2019;31:2353-2369 pubmed 出版商
Godínez Solís Y, Solís Heredia M, Roa Espitia A, Parra Forero L, Hernández González E, Hernandez Ochoa I, et al. Low concentrations of lead decrease the sperm fertilization ability by altering the acrosome reaction in mice. Toxicol Appl Pharmacol. 2019;380:114694 pubmed 出版商
Yu Y, Xiong Y, Ladeiras D, Yang Z, Ming X. Myosin 1b Regulates Nuclear AKT Activation by Preventing Localization of PTEN in the Nucleus. iScience. 2019;19:39-53 pubmed 出版商
Leung J, Cassimeris L. Reorganization of paclitaxel-stabilized microtubule arrays at mitotic entry: roles of depolymerizing kinesins and severing proteins. Cancer Biol Ther. 2019;20:1337-1347 pubmed 出版商
Tedeschi V, Petrozziello T, Sisalli M, Boscia F, Canzoniero L, Secondo A. The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance. Sci Rep. 2019;9:10743 pubmed 出版商
Geeurickx E, Tulkens J, Dhondt B, Van Deun J, Lippens L, Vergauwen G, et al. The generation and use of recombinant extracellular vesicles as biological reference material. Nat Commun. 2019;10:3288 pubmed 出版商
Palamidessi A, Malinverno C, Frittoli E, Corallino S, Barbieri E, Sigismund S, et al. Unjamming overcomes kinetic and proliferation arrest in terminally differentiated cells and promotes collective motility of carcinoma. Nat Mater. 2019;18:1252-1263 pubmed 出版商
Salmina K, Gerashchenko B, Hausmann M, Vainshelbaum N, Zayakin P, Erenpreiss J, et al. When Three Isn't a Crowd: A Digyny Concept for Treatment-Resistant, Near-Triploid Human Cancers. Genes (Basel). 2019;10: pubmed 出版商
Lee H, Wang Y, Xia W, Chen C, Rau K, Ye L, et al. Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy. Cancer Cell. 2019;36:168-178.e4 pubmed 出版商
Xu Y, Zhou P, Cheng S, Lu Q, Nowak K, Hopp A, et al. A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy. Cell. 2019;178:552-566.e20 pubmed 出版商
Park Y, Bava U, Lin J, Cornish J, Naot D, Reid I. Bone-Bound Bisphosphonates Inhibit Proliferation of Breast Cancer Cells. Calcif Tissue Int. 2019;105:497-505 pubmed 出版商
Imanikia S, Sheng M, Castro C, Griffin J, Taylor R. XBP-1 Remodels Lipid Metabolism to Extend Longevity. Cell Rep. 2019;28:581-589.e4 pubmed 出版商
Kreis N, Friemel A, Ritter A, Roth S, Rolle U, Louwen F, et al. Function of p21 (Cip1/Waf1/CDKN1A) in Migration and Invasion of Cancer and Trophoblastic Cells. Cancers (Basel). 2019;11: pubmed 出版商
Johnson S, Blount J, Libohova K, Ranxhi B, Paulson H, Tsou W, et al. Differential toxicity of ataxin-3 isoforms in Drosophila models of Spinocerebellar Ataxia Type 3. Neurobiol Dis. 2019;132:104535 pubmed 出版商
Imanikia S, Özbey N, Krueger C, Casanueva M, Taylor R. Neuronal XBP-1 Activates Intestinal Lysosomes to Improve Proteostasis in C. elegans. Curr Biol. 2019;29:2322-2338.e7 pubmed 出版商
García Ruiz I, Blanes Ruiz N, Rada P, Pardo V, Ruiz L, Blas García A, et al. Protein tyrosine phosphatase 1b deficiency protects against hepatic fibrosis by modulating nadph oxidases. Redox Biol. 2019;26:101263 pubmed 出版商
Akoume M, Elbakry M, Veillette M, Franco A, Nada D, Labelle H, et al. A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep. 2019;9:10074 pubmed 出版商
Xie L, Huang R, Liu S, Wu W, Su A, Li R, et al. A positive feedback loop of SIRT1 and miR17HG promotes the repair of DNA double-stranded breaks. Cell Cycle. 2019;18:2110-2123 pubmed 出版商
Yoo Y, Yoo T, Lee S, Lee J, Kim D, Han H, et al. Shank3 Mice Carrying the Human Q321R Mutation Display Enhanced Self-Grooming, Abnormal Electroencephalogram Patterns, and Suppressed Neuronal Excitability and Seizure Susceptibility. Front Mol Neurosci. 2019;12:155 pubmed 出版商
Abdel Nour M, Carneiro L, Downey J, Tsalikis J, Outlioua A, Prescott D, et al. The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling. Science. 2019;365: pubmed 出版商
Yamada M, Hayashi K. Microtubule nucleation in the cytoplasm of developing cortical neurons and its regulation by brain-derived neurotrophic factor. Cytoskeleton (Hoboken). 2019;76:339-345 pubmed 出版商
Mailler E, Waheed A, Park S, Gershlick D, Freed E, Bonifacino J. The autophagy protein ATG9A promotes HIV-1 infectivity. Retrovirology. 2019;16:18 pubmed 出版商
Bacci M, Lorito N, Ippolito L, Ramazzotti M, Luti S, Romagnoli S, et al. Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer. Cell Rep. 2019;28:104-118.e8 pubmed 出版商
Xu H, Shi J, Gao H, Liu Y, Yang Z, Shao F, et al. The N-end rule ubiquitin ligase UBR2 mediates NLRP1B inflammasome activation by anthrax lethal toxin. EMBO J. 2019;38:e101996 pubmed 出版商
Ravichandran R, Kodali K, Peng J, Potts P. Regulation of MAGE-A3/6 by the CRL4-DCAF12 ubiquitin ligase and nutrient availability. EMBO Rep. 2019;20:e47352 pubmed 出版商
Zhao J, Yang H, Wasala L, Zhang K, Yue Y, Duan D, et al. Dystrophin R16/17 protein therapy restores sarcolemmal nNOS in trans and improves muscle perfusion and function. Mol Med. 2019;25:31 pubmed 出版商
Cross S, McKie L, Keighren M, West K, Thaung C, Davey T, et al. Missense Mutations in the Human Nanophthalmos Gene TMEM98 Cause Retinal Defects in the Mouse. Invest Ophthalmol Vis Sci. 2019;60:2875-2887 pubmed 出版商
Parant M, Sohm B, Flayac J, Perrat E, Chuburu F, Cadiou C, et al. Impact of gadolinium-based contrast agents on the growth of fish cells lines. Ecotoxicol Environ Saf. 2019;182:109385 pubmed 出版商
Marro S, Chanda S, Yang N, Janas J, Valperga G, Trotter J, et al. Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons. Neuron. 2019;: pubmed 出版商
Zingkou E, Pampalakis G, Charla E, Nauroy P, Kiritsi D, Sotiropoulou G. A proinflammatory role of KLK6 protease in Netherton syndrome. J Dermatol Sci. 2019;95:28-35 pubmed 出版商
Nieminuszczy J, Broderick R, Bellani M, Smethurst E, Schwab R, Cherdyntseva V, et al. EXD2 Protects Stressed Replication Forks and Is Required for Cell Viability in the Absence of BRCA1/2. Mol Cell. 2019;75:605-619.e6 pubmed 出版商
Sneeggen M, Pedersen N, Campsteijn C, Haugsten E, Stenmark H, Schink K. WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling. Nat Commun. 2019;10:2850 pubmed 出版商
Raju D, Hansen J, Rassmann S, Stüven B, Jikeli J, Strünker T, et al. Cyclic Nucleotide-Specific Optogenetics Highlights Compartmentalization of the Sperm Flagellum into cAMP Microdomains. Cells. 2019;8: pubmed 出版商
El Zaoui I, Bucher M, Rimoldi D, Nicolas M, Kaya G, Pescini Gobert R, et al. Conjunctival Melanoma Targeted Therapy: MAPK and PI3K/mTOR Pathways Inhibition. Invest Ophthalmol Vis Sci. 2019;60:2764-2772 pubmed 出版商
Fujiwara D, Iwahara N, Sebori R, Hosoda R, Shimohama S, Kuno A, et al. SIRT1 deficiency interferes with membrane resealing after cell membrane injury. PLoS ONE. 2019;14:e0218329 pubmed 出版商
Liess A, Kučerová A, Schweimer K, Yu L, Roumeliotis T, Diebold M, et al. Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination. Structure. 2019;: pubmed 出版商
de Almeida L, Bauermeister A, Rezende Teixeira P, Dos Santos E, de Moraes L, Machado Neto J, et al. Pradimicin-IRD exhibits antineoplastic effects by inducing DNA damage in colon cancer cells. Biochem Pharmacol. 2019;: pubmed 出版商
Candiracci J, Migeot V, Chionh Y, Bauer F, Brochier T, Russell B, et al. Reciprocal regulation of TORC signaling and tRNA modifications by Elongator enforces nutrient-dependent cell fate. Sci Adv. 2019;5:eaav0184 pubmed 出版商
Zhao J, Zhang L, Liu N, Xu S, Yue Z, Zhang L, et al. Mutual regulation of receptor-like kinase SIT1 and B'κ-PP2A shapes the early response of rice to salt stress. Plant Cell. 2019;: pubmed 出版商
Kuldkepp A, Karakai M, Toomsoo E, Reinsalu O, Kurg R. Cancer-testis antigens MAGEA proteins are incorporated into extracellular vesicles released by cells. Oncotarget. 2019;10:3694-3708 pubmed 出版商
Zhang J, Lee Y, Dang F, Gan W, Menon A, Katon J, et al. PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage. Cancer Discov. 2019;: pubmed 出版商
Kummer S, Avinoam O, Kräusslich H. IFITM3 Clusters on Virus Containing Endosomes and Lysosomes Early in the Influenza A Infection of Human Airway Epithelial Cells. Viruses. 2019;11: pubmed 出版商
Diring J, Mouilleron S, McDonald N, Treisman R. RPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availability. Nat Cell Biol. 2019;: pubmed 出版商
Andrique L, Recher G, Alessandri K, Pujol N, Feyeux M, Bon P, et al. A model of guided cell self-organization for rapid and spontaneous formation of functional vessels. Sci Adv. 2019;5:eaau6562 pubmed 出版商
Holzmann J, Politi A, Nagasaka K, Hantsche Grininger M, Walther N, Koch B, et al. Absolute quantification of cohesin, CTCF and their regulators in human cells. elife. 2019;8: pubmed 出版商
Piacentini L, Marchetti M, Bucciarelli E, Casale A, Cappucci U, Bonifazi P, et al. A role of the Trx-G complex in Cid/CENP-A deposition at Drosophila melanogaster centromeres. Chromosoma. 2019;: pubmed 出版商
Gothe H, Bouwman B, Gusmao E, Piccinno R, Petrosino G, Sayols S, et al. Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations. Mol Cell. 2019;: pubmed 出版商
Le Berre G, Hossard V, Riou J, Guieysse Peugeot A. Repression of TERRA Expression by Subtelomeric DNA Methylation Is Dependent on NRF1 Binding. Int J Mol Sci. 2019;20: pubmed 出版商
Hoyt A, Moran A, Granger C, Sedani A, Saigh S, Brown J, et al. PRP‑1 significantly decreases the ALDHhigh cancer stem cell population and regulates the aberrant Wnt/β‑catenin pathway in human chondrosarcoma JJ012 cells. Oncol Rep. 2019;42:103-114 pubmed 出版商
Hossain D, Barbelanne M, Tsang W. Requirement of NPHP5 in the hierarchical assembly of basal feet associated with basal bodies of primary cilia. Cell Mol Life Sci. 2019;: pubmed 出版商
Liao S, Rajendraprasad G, Wang N, Eibes S, Gao J, Yu H, et al. Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis. Cell Res. 2019;: pubmed 出版商
Huang Y, Li W, Yan W, Wu J, Chen L, Yao X, et al. Loss of PICH promotes chromosome instability and cell death in triple-negative breast cancer. Cell Death Dis. 2019;10:428 pubmed 出版商
Choi Y, Park H, Jung H, Kweon H, Kim S, Lee S, et al. NGL-1/LRRC4C Deletion Moderately Suppresses Hippocampal Excitatory Synapse Development and Function in an Input-Independent Manner. Front Mol Neurosci. 2019;12:119 pubmed 出版商
Teramoto K, Katoh H. The cystine/glutamate antiporter xCT is a key regulator of EphA2 S897 phosphorylation under glucose-limited conditions. Cell Signal. 2019;62:109329 pubmed 出版商
Kozlova N, Mennerich D, Samoylenko A, Dimova E, Koivunen P, Biterova E, et al. The pro-oncogenic adaptor CIN85 acts as an inhibitory binding partner of hypoxia-inducible factor prolyl hydroxylase 2. Cancer Res. 2019;: pubmed 出版商
Caiazza C, D Agostino M, Passaro F, Faicchia D, Mallardo M, Paladino S, et al. Effects of Long-Term Citrate Treatment in the PC3 Prostate Cancer Cell Line. Int J Mol Sci. 2019;20: pubmed 出版商
Baek J, Vignesh A, Son H, Lee D, Roh G, Kang S, et al. Glutamine Supplementation Ameliorates Chronic Stress-induced Reductions in Glutamate and Glutamine Transporters in the Mouse Prefrontal Cortex. Exp Neurobiol. 2019;28:270-278 pubmed 出版商
Etemad B, Vértesy Á, Kuijt T, Sacristan C, van Oudenaarden A, Kops G. Spindle checkpoint silencing at kinetochores with submaximal microtubule occupancy. J Cell Sci. 2019;: pubmed 出版商
Shindo R, Ohmuraya M, Komazawa Sakon S, Miyake S, Deguchi Y, Yamazaki S, et al. Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal Ileitis. iScience. 2019;15:536-551 pubmed 出版商
Gu Y, Yang Y, Cao X, Zhao Y, Gao X, Sun C, et al. Plin3 protects against alcoholic liver injury by facilitating lipid export from the endoplasmic reticulum. J Cell Biochem. 2019;120:16075-16087 pubmed 出版商
Pedini F, De Luca G, Felicetti F, Puglisi R, Boe A, Arasi M, et al. Joint action of miR-126 and MAPK/PI3K inhibitors against metastatic melanoma. Mol Oncol. 2019;13:1836-1854 pubmed 出版商
Fang C, Kuo H, Hsu S, Yih L. HSP70 is required for the proper assembly of pericentriolar material and function of mitotic centrosomes. Cell Div. 2019;14:4 pubmed 出版商
Wan M, Wang X, Huang C, Xu D, Wang Z, Zhou Y, et al. A bacterial effector deubiquitinase specifically hydrolyses linear ubiquitin chains to inhibit host inflammatory signalling. Nat Microbiol. 2019;: pubmed 出版商
Viphakone N, Sudbery I, Griffith L, Heath C, Sims D, Wilson S. Co-transcriptional Loading of RNA Export Factors Shapes the Human Transcriptome. Mol Cell. 2019;: pubmed 出版商
von Samson Himmelstjerna F, Freundt G, Nitz J, Stelter F, Luedde M, Wieland T, et al. The orphan receptor GPRC5B modulates inflammatory and fibrotic pathways in cardiac fibroblasts and mice hearts. Biochem Biophys Res Commun. 2019;: pubmed 出版商
Lu W, Kim J, Tabara S, Kwon C, Mizukami H, Kimura K, et al. The N-terminal sequence of murine PRMT5 variant 2 is required for Hsp70 interaction and CHIP ligase-mediated degradation. Biochem Biophys Res Commun. 2019;: pubmed 出版商
Pirovano L, Culurgioni S, Carminati M, Alfieri A, Monzani S, Cecatiello V, et al. Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions. Nat Commun. 2019;10:2208 pubmed 出版商
Suzuki Y, Yamaguchi Y, Hanada H, Ishimi Y. Changes in MCM2-7 proteins at senescence. Genes Genet Syst. 2019;94:123-132 pubmed 出版商
To C, Jang J, Chen T, Park E, Mushajiang M, De Clercq D, et al. Single and dual targeting of mutant EGFR with an allosteric inhibitor. Cancer Discov. 2019;: pubmed 出版商
Hu X, Feng J, Huang X, Lu P, Wang Z, Dai H, et al. Histone deacetylases up-regulate C/EBPα expression through reduction of miR-124-3p and miR-25 in hepatocellular carcinoma. Biochem Biophys Res Commun. 2019;: pubmed 出版商
Stasic A, Chasen N, Dykes E, Vella S, Asady B, Starai V, et al. The Toxoplasma Vacuolar H+-ATPase Regulates Intracellular pH and Impacts the Maturation of Essential Secretory Proteins. Cell Rep. 2019;27:2132-2146.e7 pubmed 出版商
Domingo Prim J, Endara Coll M, Bonath F, Jimeno S, Prados Carvajal R, Friedländer M, et al. EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks. Nat Commun. 2019;10:2135 pubmed 出版商
Ansar M, Ullah F, Paracha S, Adams D, Lai A, Pais L, et al. Bi-allelic Variants in DYNC1I2 Cause Syndromic Microcephaly with Intellectual Disability, Cerebral Malformations, and Dysmorphic Facial Features. Am J Hum Genet. 2019;104:1073-1087 pubmed 出版商
Lombard A, Liu C, Armstrong C, D Abronzo L, Lou W, Chen H, et al. Overexpressed ABCB1 Induces Olaparib-Taxane Cross-Resistance in Advanced Prostate Cancer. Transl Oncol. 2019;12:871-878 pubmed 出版商
Mikoda N, Sonoda H, Oshikawa S, Hoshino Y, Matsuzaki T, Ikeda M. A bell-shaped pattern of urinary aquaporin-2-bearing extracellular vesicle release in an experimental model of nephronophthisis. Physiol Rep. 2019;7:e14092 pubmed 出版商
Sprott D, Poitz D, Korovina I, Ziogas A, Phieler J, Chatzigeorgiou A, et al. Endothelial-Specific Deficiency of ATG5 (Autophagy Protein 5) Attenuates Ischemia-Related Angiogenesis. Arterioscler Thromb Vasc Biol. 2019;39:1137-1148 pubmed 出版商
Hamon A, García García D, Ail D, Bitard J, Chesneau A, Dalkara D, et al. Linking YAP to Müller Glia Quiescence Exit in the Degenerative Retina. Cell Rep. 2019;27:1712-1725.e6 pubmed 出版商
Thawani A, Stone H, Shaevitz J, Petry S. Spatiotemporal organization of branched microtubule networks. elife. 2019;8: pubmed 出版商
Larochelle M, Bergeron D, Arcand B, Bachand F. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. J Cell Sci. 2019;132: pubmed 出版商
Zhao L, Li L, Xu H, Ke H, Zou L, Yang Q, et al. TDP-43 is required for mammary gland repopulation and proliferation of mammary epithelial cells. Stem Cells Dev. 2019;: pubmed 出版商
Nguyen E, Pereira B, Lawrence M, Ma X, Rebello R, Chan H, et al. Proteomic profiling of human prostate cancer-associated fibroblasts (CAF) reveals LOXL2-dependent regulation of the tumor microenvironment. Mol Cell Proteomics. 2019;: pubmed 出版商
Desuki A, Staib F, Gockel I, Moehler M, Lang H, Biesterfeld S, et al. Loss of LLGL1 Expression Correlates with Diffuse Gastric Cancer and Distant Peritoneal Metastases. Can J Gastroenterol Hepatol. 2019;2019:2920493 pubmed 出版商
Xian H, Yang Q, Xiao L, Shen H, Liou Y. STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism. Nat Commun. 2019;10:2059 pubmed 出版商
Cronise K, Hernandez B, Gustafson D, Duval D. Identifying the ErbB/MAPK Signaling Cascade as a Therapeutic Target in Canine Bladder Cancer. Mol Pharmacol. 2019;96:36-46 pubmed 出版商
Davis M, Delaleau M, Borden K. Nuclear eIF4E Stimulates 3'-End Cleavage of Target RNAs. Cell Rep. 2019;27:1397-1408.e4 pubmed 出版商
Chai Q, Wang X, Qiang L, Zhang Y, Ge P, Lu Z, et al. A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy. Nat Commun. 2019;10:1973 pubmed 出版商
Dewulf M, Köster D, Sinha B, Viaris de Lesegno C, Chambon V, Bigot A, et al. Dystrophy-associated caveolin-3 mutations reveal that caveolae couple IL6/STAT3 signaling with mechanosensing in human muscle cells. Nat Commun. 2019;10:1974 pubmed 出版商
Trautsch I, Heta E, Soong P, Levent E, Nikolaev V, Bogeski I, et al. Optogenetic Monitoring of the Glutathione Redox State in Engineered Human Myocardium. Front Physiol. 2019;10:272 pubmed 出版商
Grant M, Shapiro S, Ashe K, Liu P, Zahs K. A Cautionary Tale: Endogenous Biotinylated Proteins and Exogenously-Introduced Protein A Cause Antibody-Independent Artefacts in Western Blot Studies of Brain-Derived Proteins. Biol Proced Online. 2019;21:6 pubmed 出版商
Zhou X, Li W, Wang S, Zhang P, Wang Q, Xiao J, et al. YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis. Cell Rep. 2019;27:1176-1189.e5 pubmed 出版商
Barak B, Zhang Z, Liu Y, Nir A, Trangle S, Ennis M, et al. Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioral and myelin alterations rescuable by a remyelinating drug. Nat Neurosci. 2019;22:700-708 pubmed 出版商
Hytti M, Korhonen E, Hyttinen J, Roehrich H, Kaarniranta K, Ferrington D, et al. Antimycin A-Induced Mitochondrial Damage Causes Human RPE Cell Death despite Activation of Autophagy. Oxid Med Cell Longev. 2019;2019:1583656 pubmed 出版商
Chen W, Schwalie P, Pankevich E, Gubelmann C, Raghav S, Dainese R, et al. ZFP30 promotes adipogenesis through the KAP1-mediated activation of a retrotransposon-derived Pparg2 enhancer. Nat Commun. 2019;10:1809 pubmed 出版商
Yamamoto S, Kitagawa D. Self-organization of Plk4 regulates symmetry breaking in centriole duplication. Nat Commun. 2019;10:1810 pubmed 出版商
Rehman M, Vodret S, Braga L, Guarnaccia C, Celsi F, Rossetti G, et al. High-throughput screening discovers antifibrotic properties of haloperidol by hindering myofibroblast activation. JCI Insight. 2019;4: pubmed 出版商
Bazzoun D, Adissu H, Wang L, Urazaev A, Tenvooren I, Fostok S, et al. Connexin 43 maintains tissue polarity and regulates mitotic spindle orientation in the breast epithelium. J Cell Sci. 2019;132: pubmed 出版商
Wouters E, Marín A, Dalton J, Giraldo J, Stove C. Distinct Dopamine D₂ Receptor Antagonists Differentially Impact D₂ Receptor Oligomerization. Int J Mol Sci. 2019;20: pubmed 出版商
Princely Abudu Y, Pankiv S, Mathai B, Håkon Lystad A, Bindesbøll C, Brenne H, et al. NIPSNAP1 and NIPSNAP2 Act as "Eat Me" Signals for Mitophagy. Dev Cell. 2019;49:509-525.e12 pubmed 出版商
Pesce L, Cozzolino M, Lanzano L, Diaspro A, Bianchini P. Measuring expansion from macro- to nanoscale using NPC as intrinsic reporter. J Biophotonics. 2019;12:e201900018 pubmed 出版商
Pampalakis G, Zingkou E, Sidiropoulos K, Diamandis E, Zoumpourlis V, Yousef G, et al. Biochemical pathways mediated by KLK6 protease in breast cancer. Mol Oncol. 2019;13:2329-2343 pubmed 出版商
Ding J, Pan X, Du L, Yao Q, Xue J, Yao H, et al. Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector. Mol Cell. 2019;74:922-935.e6 pubmed 出版商
Guo S, Ran H, Xiao D, Huang H, Mi L, Wang X, et al. NT5DC2 promotes tumorigenicity of glioma stem-like cells by upregulating fyn. Cancer Lett. 2019;454:98-107 pubmed 出版商
Ducheyne K, Rizzo M, Daels P, Stout T, de Ruijter Villani M. Vitrifying immature equine oocytes impairs their ability to correctly align the chromosomes on the MII spindle. Reprod Fertil Dev. 2019;: pubmed 出版商
van Groningen T, Akogul N, Westerhout E, Chan A, Hasselt N, Zwijnenburg D, et al. A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma. Nat Commun. 2019;10:1530 pubmed 出版商
Jiang Y, Zhang Y, Leung J, Fan C, Popov K, Su S, et al. MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression. Nat Commun. 2019;10:1515 pubmed 出版商
Le Gal L, Pellegrin M, Santoro T, Mazzolai L, Kurtz A, Meda P, et al. Connexin37-Dependent Mechanisms Selectively Contribute to Modulate Angiotensin II -Mediated Hypertension. J Am Heart Assoc. 2019;8:e010823 pubmed 出版商
Lecland N, Hsu C, Chemin C, Merdes A, Bierkamp C. Epidermal development requires ninein for spindle orientation and cortical microtubule organization. Life Sci Alliance. 2019;2: pubmed 出版商
Cantù I, van de Werken H, Gillemans N, Stadhouders R, Heshusius S, Maas A, et al. The mouse KLF1 Nan variant impairs nuclear condensation and erythroid maturation. PLoS ONE. 2019;14:e0208659 pubmed 出版商
Werthebach M, Stewart F, Gahlen A, Mettler Altmann T, Akhtar I, Maas Enriquez K, et al. Control of Drosophila Growth and Survival by the Lipid Droplet-Associated Protein CG9186/Sturkopf. Cell Rep. 2019;26:3726-3740.e7 pubmed 出版商
Anticoli S, Amatore D, Matarrese P, De Angelis M, Palamara A, Nencioni L, et al. Counteraction of HCV-Induced Oxidative Stress Concurs to Establish Chronic Infection in Liver Cell Cultures. Oxid Med Cell Longev. 2019;2019:6452390 pubmed 出版商
Stroukov W, Rösch A, Schwan C, Jeney A, Römer W, Thuenauer R. Synchronizing Protein Traffic to the Primary Cilium. Front Genet. 2019;10:163 pubmed 出版商
Lee R, Zhang L, Berger A, Lawrence M, Song J, Niranjan B, et al. Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target. Neoplasia. 2019;21:389-400 pubmed 出版商
Bolduc V, Foley A, Solomon Degefa H, Sarathy A, Donkervoort S, Hu Y, et al. A recurrent COL6A1 pseudoexon insertion causes muscular dystrophy and is effectively targeted by splice-correction therapies. JCI Insight. 2019;4: pubmed 出版商
Chakraborty A, Laukka T, Myllykoski M, Ringel A, Booker M, Tolstorukov M, et al. Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate. Science. 2019;363:1217-1222 pubmed 出版商
Takacs Z, Sporbeck K, Stoeckle J, Prado Carvajal M, Grimmel M, Proikas Cezanne T. ATG-18 and EPG-6 are Both Required for Autophagy but Differentially Contribute to Lifespan Control in Caenorhabditis elegans. Cells. 2019;8: pubmed 出版商
Hartl M, Glasauer S, Gufler S, Raffeiner A, Puglisi K, Breuker K, et al. Differential regulation of myc homologs by Wnt/β-Catenin signaling in the early metazoan Hydra. FEBS J. 2019;286:2295-2310 pubmed 出版商
Scherzad A, Gehrke T, Meyer T, Ickrath P, Bregenzer M, Eiter R, et al. Wound fluid enhances cancer cell proliferation via activation of STAT3 signal pathway in vitro. Oncol Rep. 2019;41:2919-2926 pubmed 出版商
Sun Z, Liu J. mTOR-S6K1 pathway mediates cytoophidium assembly. J Genet Genomics. 2019;46:65-74 pubmed 出版商
Felip I, Moiola C, Megino Luque C, Lopez Gil C, Cabrera S, Solé Sánchez S, et al. Therapeutic potential of the new TRIB3-mediated cell autophagy anticancer drug ABTL0812 in endometrial cancer. Gynecol Oncol. 2019;153:425-435 pubmed 出版商
Xu S, Wu W, Huang H, Huang R, Xie L, Su A, et al. The p53/miRNAs/Ccna2 pathway serves as a novel regulator of cellular senescence: Complement of the canonical p53/p21 pathway. Aging Cell. 2019;18:e12918 pubmed 出版商
Zhao H, Chen Q, Fang C, Huang Q, Zhou J, Yan X, et al. Parental centrioles are dispensable for deuterosome formation and function during basal body amplification. EMBO Rep. 2019;20: pubmed 出版商
Ishikawa K, Kobayashi K, Yamada A, Umehara M, Oka T, Nakada K. Concentration of mitochondrial DNA mutations by cytoplasmic transfer from platelets to cultured mouse cells. PLoS ONE. 2019;14:e0213283 pubmed 出版商
Vallardi G, Allan L, Crozier L, Saurin A. Division of labour between PP2A-B56 isoforms at the centromere and kinetochore. elife. 2019;8: pubmed 出版商
Federico A, Sepe R, Cozzolino F, Piccolo C, Iannone C, Iacobucci I, et al. The complex CBX7-PRMT1 has a critical role in regulating E-cadherin gene expression and cell migration. Biochim Biophys Acta Gene Regul Mech. 2019;1862:509-521 pubmed 出版商
Chen S, Wang R, Zheng D, Zhang H, Chang X, Wang K, et al. The mRNA Export Receptor NXF1 Coordinates Transcriptional Dynamics, Alternative Polyadenylation, and mRNA Export. Mol Cell. 2019;74:118-131.e7 pubmed 出版商
Park J, Jin M, Hur M, Nam A, Bang J, Won J, et al. GC1118, a novel anti-EGFR antibody, has potent KRAS mutation-independent antitumor activity compared with cetuximab in gastric cancer. Gastric Cancer. 2019;: pubmed 出版商
Ali H, Mano M, Braga L, Naseem A, Marini B, Vu D, et al. Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation. Nat Commun. 2019;10:926 pubmed 出版商
Sharma N, Rao S, Kalivendi S. The deglycase activity of DJ-1 mitigates α-synuclein glycation and aggregation in dopaminergic cells: Role of oxidative stress mediated downregulation of DJ-1 in Parkinson's disease. Free Radic Biol Med. 2019;135:28-37 pubmed 出版商
Bergeron F, Boulende Sab A, Bouchard M, Taniguchi H, Souchkova O, Brousseau C, et al. Phosphorylation of GATA4 serine 105 but not serine 261 is required for testosterone production in the male mouse. Andrology. 2019;7:357-372 pubmed 出版商
Kim A, Choi K. TRiC/CCT chaperonins are essential for organ growth by interacting with insulin/TOR signaling in Drosophila. Oncogene. 2019;38:4739-4754 pubmed 出版商
Bizkarguenaga M, Gomez Santos L, Madrid J, Saez F, Alonso E. Increase of germ cell nuclear factor expression in globozoospermic Gopc-/- knockout mice. Andrology. 2019;7:319-328 pubmed 出版商
Lee S, Lee J, Lee E, Park S, Kang D, Min C, et al. Absence of Cytosolic 2-Cys Prx Subtypes I and II Exacerbates TNF-α-Induced Apoptosis via Different Routes. Cell Rep. 2019;26:2194-2211.e6 pubmed 出版商
Pachis S, Hiruma Y, Tromer E, Perrakis A, Kops G. Interactions between N-terminal Modules in MPS1 Enable Spindle Checkpoint Silencing. Cell Rep. 2019;26:2101-2112.e6 pubmed 出版商
Lacefield C, Pnevmatikakis E, Paninski L, Bruno R. Reinforcement Learning Recruits Somata and Apical Dendrites across Layers of Primary Sensory Cortex. Cell Rep. 2019;26:2000-2008.e2 pubmed 出版商
Wang Z, Gong Y, Peng B, Shi R, Fan D, Zhao H, et al. MRE11 UFMylation promotes ATM activation. Nucleic Acids Res. 2019;47:4124-4135 pubmed 出版商
Ivanov V, Wu J, Wang T, Hei T. Inhibition of ATM kinase upregulates levels of cell death induced by cannabidiol and γ-irradiation in human glioblastoma cells. Oncotarget. 2019;10:825-846 pubmed 出版商
Cordone V, Pecorelli A, Benedusi M, Santini S, Falone S, Hayek J, et al. Antiglycative Activity and RAGE Expression in Rett Syndrome. Cells. 2019;8: pubmed 出版商
Ling C, Liu Z, Song M, Zhang W, Wang S, Liu X, et al. Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells. Protein Cell. 2019;10:249-271 pubmed 出版商
Gendre D, Baral A, Dang X, Esnay N, Boutté Y, Stanislas T, et al. Rho-of-plant activated root hair formation requires Arabidopsis YIP4a/b gene function. Development. 2019;146: pubmed 出版商
Hirai Y, Domae E, Yoshikawa Y, Okamura H, Makino A, Tomonaga K. Intracellular dynamics of actin affects Borna disease virus replication in the nucleus. Virus Res. 2019;263:179-183 pubmed 出版商
Feleciano D, Juenemann K, Iburg M, Brás I, Holmberg C, Kirstein J. Crosstalk Between Chaperone-Mediated Protein Disaggregation and Proteolytic Pathways in Aging and Disease. Front Aging Neurosci. 2019;11:9 pubmed 出版商
Wang W, Hsu J, Wang Y, Lee H, Yamaguchi H, Liao H, et al. An essential role of PRMT1-mediated EGFR methylation in EGFR activation by ribonuclease 5. Am J Cancer Res. 2019;9:180-185 pubmed
McRae H, Garnham A, Hu Y, Witkowski M, Corbett M, Dixon M, et al. PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia. Blood. 2019;: pubmed 出版商
Tassinari V, De Gennaro V, La Sala G, Marazziti D, Bolasco G, Aguanno S, et al. Atrophy, oxidative switching and ultrastructural defects in skeletal muscle of the ataxia telangiectasia mouse model. J Cell Sci. 2019;132: pubmed 出版商
Bartholomew T, Kidd T, Sá Pessoa J, Conde Alvarez R, Bengoechea J. 2-Hydroxylation of Acinetobacter baumannii Lipid A Contributes to Virulence. Infect Immun. 2019;87: pubmed 出版商
Yeshaw W, van der Zwaag M, Pinto F, Lahaye L, Faber A, Gómez Sánchez R, et al. Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility. elife. 2019;8: pubmed 出版商
Fusté N, Guasch M, Guillen P, Anerillas C, Cemeli T, Pedraza N, et al. Barley β-glucan accelerates wound healing by favoring migration versus proliferation of human dermal fibroblasts. Carbohydr Polym. 2019;210:389-398 pubmed 出版商
Suvorova I, Knyazeva A, Petukhov A, Aksenov N, Pospelov V. Resveratrol enhances pluripotency of mouse embryonic stem cells by activating AMPK/Ulk1 pathway. Cell Death Discov. 2019;5:61 pubmed 出版商
Adriaans I, Basant A, Ponsioen B, Glotzer M, Lens S. PLK1 plays dual roles in centralspindlin regulation during cytokinesis. J Cell Biol. 2019;218:1250-1264 pubmed 出版商
Nandagopalan S, Agatheeswaran S, Vadlamudi Y, Biswas S, Biswas G, Pattnayak N, et al. PTBP2 exon 10 inclusion is associated with the progression of CML and it is BCR-ABL1 dependent. Int J Biochem Cell Biol. 2019;109:69-75 pubmed 出版商
Ramia E, Chiaravalli A, Bou Nasser Eddine F, Tedeschi A, Sessa F, Accolla R, et al. CIITA-related block of HLA class II expression, upregulation of HLA class I, and heterogeneous expression of immune checkpoints in hepatocarcinomas: implications for new therapeutic approaches. Oncoimmunology. 2019;8:1548243 pubmed 出版商
Lin C, Chao Y, Chen W, Ho H, Chou M, Li Y, et al. Regulatory cascade involving transcriptional and N-end rule pathways in rice under submergence. Proc Natl Acad Sci U S A. 2019;116:3300-3309 pubmed 出版商
Motuhi S, Feizbakhsh O, Foll Josselin B, Baratte B, Delehouze C, Cousseau A, et al. Neurymenolide A, a Novel Mitotic Spindle Poison from the New Caledonian Rhodophyta Phacelocarpus neurymenioides. Mar Drugs. 2019;17: pubmed 出版商
Pigna E, Simonazzi E, Sanna K, Bernadzki K, Proszynski T, Heil C, et al. Histone deacetylase 4 protects from denervation and skeletal muscle atrophy in a murine model of amyotrophic lateral sclerosis. EBioMedicine. 2019;40:717-732 pubmed 出版商
Fukuda M, Sakaue Sawano A, Shimura C, Tachibana M, Miyawaki A, Shinkai Y. G9a-dependent histone methylation can be induced in G1 phase of cell cycle. Sci Rep. 2019;9:956 pubmed 出版商
Terra L, Wailemann R, Dos Santos A, Gomes V, Silva R, Laporte A, et al. Heat shock protein B1 is a key mediator of prolactin-induced beta-cell cytoprotection against oxidative stress. Free Radic Biol Med. 2019;134:394-405 pubmed 出版商
Biskou O, Casanova V, Hooper K, Kemp S, Wright G, Satsangi J, et al. The type III intermediate filament vimentin regulates organelle distribution and modulates autophagy. PLoS ONE. 2019;14:e0209665 pubmed 出版商
Köhler K, Sanchez Pulido L, Höfer V, Marko A, Ponting C, Snijders A, et al. The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7. PLoS Biol. 2019;17:e2006767 pubmed 出版商
Milesi C, Alberici P, Pozzi B, Oldani A, Beznoussenko G, Raimondi A, et al. Redundant and nonredundant organismal functions of EPS15 and EPS15L1. Life Sci Alliance. 2019;2: pubmed 出版商
Salmina K, Huna A, Kalejs M, Pjanova D, Scherthan H, Cragg M, et al. The Cancer Aneuploidy Paradox: In the Light of Evolution. Genes (Basel). 2019;10: pubmed 出版商
Anderson M, Moss J, Szalai R, Lane J. Mathematical Modeling Highlights the Complex Role of AKT in TRAIL-Induced Apoptosis of Colorectal Carcinoma Cells. iScience. 2019;12:182-193 pubmed 出版商
Gong J, Zhou S, Yang S. Vanillic Acid Suppresses HIF-1α Expression via Inhibition of mTOR/p70S6K/4E-BP1 and Raf/MEK/ERK Pathways in Human Colon Cancer HCT116 Cells. Int J Mol Sci. 2019;20: pubmed 出版商
Cui H, Banerjee S, Guo S, Xie N, Ge J, Jiang D, et al. Long noncoding RNA Malat1 regulates differential activation of macrophages and response to lung injury. JCI Insight. 2019;4: pubmed 出版商
Hernandez G, Mahmoudi S, Cyr M, Diaz J, Blanchet P, Levesque D. Tardive dyskinesia is associated with altered putamen Akt/GSK-3β signaling in nonhuman primates. Mov Disord. 2019;34:717-726 pubmed 出版商
Pai C, Hsu K, Durley S, Keszthelyi A, Kearsey S, Rallis C, et al. An essential role for dNTP homeostasis following CDK-induced replication stress. J Cell Sci. 2019;132: pubmed 出版商
Becares N, Gage M, Voisin M, Shrestha E, Martin Gutierrez L, Liang N, et al. Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease. Cell Rep. 2019;26:984-995.e6 pubmed 出版商
Woeste M, Stern S, Raju D, Grahn E, Dittmann D, Gutbrod K, et al. Species-specific differences in nonlysosomal glucosylceramidase GBA2 function underlie locomotor dysfunction arising from loss-of-function mutations. J Biol Chem. 2019;294:3853-3871 pubmed 出版商
Ericksen R, Lim S, McDonnell E, Shuen W, Vadiveloo M, White P, et al. Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression. Cell Metab. 2019;: pubmed 出版商
Lee J, Ismail A, Lee J, Zhou X, Materne E, Chodosh J, et al. Impact of dynamin 2 on adenovirus nuclear entry. Virology. 2019;529:43-56 pubmed 出版商
Sanz M, González Almela E, Garcia Moreno M, Marina A, Carrasco L. A VIRAL RNA MOTIF INVOLVED IN SIGNALLING THE INITIATION OF TRANSLATION ON NON-AUG CODONS. RNA. 2019;: pubmed 出版商
Hoshino Y, Sonoda H, Nishimura R, Mori K, Ishibashi K, Ikeda M. Involvement of the NADPH oxidase 2 pathway in renal oxidative stress in Aqp11-/- mice. Biochem Biophys Rep. 2019;17:169-176 pubmed 出版商
Correia S, Chan A, Vaughan M, Zolboot N, Perea V, Huber A, et al. The circadian E3 ligase complex SCFFBXL3+CRY targets TLK2. Sci Rep. 2019;9:198 pubmed 出版商
Ma X, Zhang L, Song J, Nguyen E, Lee R, Rodgers S, et al. Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation. Nat Commun. 2019;10:296 pubmed 出版商
Wu M, Chang Y, Hu H, Mu R, Zhang Y, Qin X, et al. LUBAC controls chromosome alignment by targeting CENP-E to attached kinetochores. Nat Commun. 2019;10:273 pubmed 出版商
Arhzaouy K, Papadopoulos C, Schulze N, Pittman S, Meyer H, Weihl C. VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle. Autophagy. 2019;:1-18 pubmed 出版商
Ye W, Li Z, Tang T, Du J, Zhou X, Wu H, et al. ERp29 downregulation enhances lung adenocarcinoma cell chemosensitivity to gemcitabine by upregulating HSP27 phosphorylation. Exp Ther Med. 2019;17:817-823 pubmed 出版商
Yan K, Liu J, Guan X, Yin Y, Peng H, Chen H, et al. The Carboxyl Terminus of Tegument Protein pUL21 Contributes to Pseudorabies Virus Neuroinvasion. J Virol. 2019;93: pubmed 出版商
Gerber D, Ghidinelli M, Tinelli E, Somandin C, Gerber J, Pereira J, et al. Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function. elife. 2019;8: pubmed 出版商
Limbocker R, Chia S, Ruggeri F, Perni M, Cascella R, Heller G, et al. Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes. Nat Commun. 2019;10:225 pubmed 出版商
Solomon Zemler R, Pozniak Y, Geiger T, Werner H. Identification of nucleolar protein NOM1 as a novel nuclear IGF1R-interacting protein. Mol Genet Metab. 2019;126:259-265 pubmed 出版商
Bellissimo T, Tito C, Ganci F, Sacconi A, Masciarelli S, di Martino G, et al. Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells. Cell Death Dis. 2019;10:17 pubmed 出版商
Sergeeva O, van der Goot F. Anthrax toxin requires ZDHHC5-mediated palmitoylation of its surface-processing host enzymes. Proc Natl Acad Sci U S A. 2019;116:1279-1288 pubmed 出版商
Ishikawa K, Yamamoto S, Hattori S, Nishimura N, Tani H, Mito T, et al. Acquired Expression of Mutant Mitofusin 2 Causes Progressive Neurodegeneration and Abnormal Behavior. J Neurosci. 2019;39:1588-1604 pubmed 出版商
Garcia D, Hellberg K, Chaix A, Wallace M, Herzig S, Badur M, et al. Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD. Cell Rep. 2019;26:192-208.e6 pubmed 出版商
Zhang J, Chen M, Zhu Y, Dai X, Dang F, Ren J, et al. SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression. Dev Cell. 2019;48:329-344.e5 pubmed 出版商
Fang X, Zhao G, Zhang S, Li Y, Gu H, Li Y, et al. Chloroplast-to-Nucleus Signaling Regulates MicroRNA Biogenesis in Arabidopsis. Dev Cell. 2019;48:371-382.e4 pubmed 出版商
Chou A, Aslanian A, Sun H, Hunter T. An internal ribosome entry site in the coding region of tyrosyl-DNA phosphodiesterase 2 drives alternative translation start. J Biol Chem. 2019;294:2665-2677 pubmed 出版商
Nishibuchi G, Machida S, Nakagawa R, Yoshimura Y, Hiragami Hamada K, Abe Y, et al. Mitotic phosphorylation of HP1α regulates its cell cycle-dependent chromatin binding. J Biochem. 2019;165:433-446 pubmed 出版商
Festa B, Berquez M, Gassama A, Amrein I, Ismail H, Samardzija M, et al. OCRL deficiency impairs endolysosomal function in a humanized mouse model for Lowe syndrome and Dent disease. Hum Mol Genet. 2019;28:1931-1946 pubmed 出版商
Champion L, Pawar S, Luithle N, Ungricht R, Kutay U. Dissociation of membrane-chromatin contacts is required for proper chromosome segregation in mitosis. Mol Biol Cell. 2019;30:427-440 pubmed 出版商
Abbasi S, Schild Poulter C. Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells. J Proteome Res. 2019;18:1064-1077 pubmed 出版商
Volkmar N, Thezenas M, Louie S, Juszkiewicz S, Nomura D, Hegde R, et al. The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis. J Cell Sci. 2019;132: pubmed 出版商
Kasioumi P, Vrazeli P, Vezyraki P, Zerikiotis S, Katsouras C, Damalas A, et al. Hsp70 (HSP70A1A) downregulation enhances the metastatic ability of cancer cells. Int J Oncol. 2019;54:821-832 pubmed 出版商
Gambarotto D, Zwettler F, Le Guennec M, Schmidt Cernohorska M, Fortun D, Borgers S, et al. Imaging cellular ultrastructures using expansion microscopy (U-ExM). Nat Methods. 2019;16:71-74 pubmed 出版商
Forrester A, De Leonibus C, Grumati P, Fasana E, Piemontese M, Staiano L, et al. A selective ER-phagy exerts procollagen quality control via a Calnexin-FAM134B complex. EMBO J. 2019;38: pubmed 出版商
de Rosa V, Secondo A, Pannaccione A, Ciccone R, Formisano L, Guida N, et al. D-Aspartate treatment attenuates myelin damage and stimulates myelin repair. EMBO Mol Med. 2019;11: pubmed 出版商
Narayana Y, Gadgil C, Mote R, Rajan R, Subramanyam D. Clathrin-Mediated Endocytosis Regulates a Balance between Opposing Signals to Maintain the Pluripotent State of Embryonic Stem Cells. Stem Cell Reports. 2019;12:152-164 pubmed 出版商
Tsuruta Y, Shibutani S, Watanabe R, Iwata H. Apoptosis induced by Ibaraki virus does not affect virus replication and cell death in hamster lung HmLu-1 cells. J Vet Med Sci. 2019;81:197-203 pubmed 出版商
Vandemoortele G, De Sutter D, Moliere A, Pauwels J, Gevaert K, Eyckerman S. A Well-Controlled BioID Design for Endogenous Bait Proteins. J Proteome Res. 2019;18:95-106 pubmed 出版商
Liu X, Zhang S, McGeary M, Krykbaeva I, Lai L, Jansen D, et al. KDM5B Promotes Drug Resistance by Regulating Melanoma-Propagating Cell Subpopulations. Mol Cancer Ther. 2019;18:706-717 pubmed 出版商
Glenn S, Geyer P. Investigation of the Developmental Requirements of Drosophila HP1 and Insulator Protein Partner, HIPP1. G3 (Bethesda). 2019;9:345-357 pubmed 出版商
Nam A, Jin M, Park J, Bang J, Oh D, Bang Y. Therapeutic Targeting of the DNA Damage Response Using an ATR Inhibitor in Biliary Tract Cancer. Cancer Res Treat. 2019;51:1167-1179 pubmed 出版商
Liu Z, Cai H, Xue W, Wang M, Xia T, Li W, et al. G3BP1 promotes DNA binding and activation of cGAS. Nat Immunol. 2019;20:18-28 pubmed 出版商
Yu N, Xue M, Wang W, Xia D, Li Y, Zhou X, et al. RNF168 facilitates proliferation and invasion of esophageal carcinoma, possibly via stabilizing STAT1. J Cell Mol Med. 2019;23:1553-1561 pubmed 出版商
Kobayashi H, Shoji K, Kiyokawa K, Negishi L, Tomari Y. Iruka Eliminates Dysfunctional Argonaute by Selective Ubiquitination of Its Empty State. Mol Cell. 2019;73:119-129.e5 pubmed 出版商
Urbanska M, Kazmierska Grebowska P, Kowalczyk T, Caban B, Nader K, Pijet B, et al. GSK3β activity alleviates epileptogenesis and limits GluA1 phosphorylation. EBioMedicine. 2019;39:377-387 pubmed 出版商
Bikkul M, Faragher R, Worthington G, Meinke P, Kerr A, Sammy A, et al. Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform. Genes Chromosomes Cancer. 2019;58:341-356 pubmed 出版商
Torres Adorno A, Vitrac H, Qi Y, Tan L, Levental K, Fan Y, et al. Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux. Oncogene. 2019;38:2135-2150 pubmed 出版商
Minniti A, Arriagada H, Zúñiga S, Bravo Zehnder M, Alfaro I, Aldunate R. Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis. Aging Cell. 2019;18:e12855 pubmed 出版商
Okamoto Y, Abe M, Itaya A, Tomida J, Ishiai M, Takaori Kondo A, et al. FANCD2 protects genome stability by recruiting RNA processing enzymes to resolve R-loops during mild replication stress. FEBS J. 2019;286:139-150 pubmed 出版商
Chiang T, Lin M, Tsai M, Chen C, Jang L, Lee F. ADP-ribosylation factor-like 4A interacts with Robo1 to promote cell migration by regulating Cdc42 activation. Mol Biol Cell. 2019;30:69-81 pubmed 出版商
Du S, Sarver J, Trabbic C, Erhardt P, Schroering A, Maltese W. 6-MOMIPP, a novel brain-penetrant anti-mitotic indolyl-chalcone, inhibits glioblastoma growth and viability. Cancer Chemother Pharmacol. 2019;83:237-254 pubmed 出版商
Nguyen K, Lee C, Mun S, Truong N, Park S, Hwang C. N-terminal acetylation and the N-end rule pathway control degradation of the lipid droplet protein PLIN2. J Biol Chem. 2019;294:379-388 pubmed 出版商
Osmanagic Myers S, Kiss A, Manakanatas C, Hamza O, Sedlmayer F, Szabo P, et al. Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse. J Clin Invest. 2019;129:531-545 pubmed 出版商
CHENG A, Yockteng Melgar J, Jarvis M, Malik Soni N, Borozan I, Carpenter M, et al. Epstein-Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity. Nat Microbiol. 2019;4:78-88 pubmed 出版商
Uchida R, Xiang H, Arai H, Kitamura H, Nishida K. L-Type Calcium Channel-Mediated Zinc Wave Is Involved in the Regulation of IL-6 by Stimulating Non-IgE with LPS and IL-33 in Mast Cells and Dendritic Cells. Biol Pharm Bull. 2019;42:87-93 pubmed 出版商
Eichner L, Brun S, Herzig S, Young N, Curtis S, Shackelford D, et al. Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models. Cell Metab. 2019;29:285-302.e7 pubmed 出版商
Wang L, Yan Z, Vihinen H, Eriksson O, Wang W, Soliymani R, et al. FAM92A1 is a BAR domain protein required for mitochondrial ultrastructure and function. J Cell Biol. 2019;218:97-111 pubmed 出版商
Lu M, Banetta L, Young L, Smith E, Bates G, Zaccone A, et al. Live-cell super-resolution microscopy reveals a primary role for diffusion in polyglutamine-driven aggresome assembly. J Biol Chem. 2019;294:257-268 pubmed 出版商
Zerikiotis S, Angelidis C, Dhima I, Naka K, Kasioumi P, Kalfakakou V, et al. The increased expression of the inducible Hsp70 (HSP70A1A) in serum of patients with heart failure and its protective effect against the cardiotoxic agent doxorubicin. Mol Cell Biochem. 2019;455:41-59 pubmed 出版商
Reilly M, Stokman M, Magry V, Jeanpierre C, Alves M, Paydar M, et al. Loss-of-function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish. Hum Mol Genet. 2019;28:778-795 pubmed 出版商
Gong X, Du J, Parsons S, Merzoug F, Webster Y, Iversen P, et al. Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene. Cancer Discov. 2019;9:248-263 pubmed 出版商
Su H, Wu Y, Fang Y, Shen L, Fei Z, Xie C, et al. MicroRNA‑301a targets WNT1 to suppress cell proliferation and migration and enhance radiosensitivity in esophageal cancer cells. Oncol Rep. 2019;41:599-607 pubmed 出版商
Neelagandan N, Gonnella G, Dang S, Janiesch P, Miller K, Küchler K, et al. TDP-43 enhances translation of specific mRNAs linked to neurodegenerative disease. Nucleic Acids Res. 2019;47:341-361 pubmed 出版商
Bhalla M, Van Ngo H, Gyanwali G, Ireton K. The Host Scaffolding Protein Filamin A and the Exocyst Complex Control Exocytosis during InlB-Mediated Entry of Listeria monocytogenes. Infect Immun. 2019;87: pubmed 出版商
Astashchanka A, Shroka T, Jacobsen B. Mucin 2 (MUC2) modulates the aggressiveness of breast cancer. Breast Cancer Res Treat. 2019;173:289-299 pubmed 出版商
Lyu J, Kim J, Chu H, Taylor M, Jung S, Baek S, et al. Natural allelic variation of GVS1 confers diversity in the regulation of leaf senescence in Arabidopsis. New Phytol. 2019;221:2320-2334 pubmed 出版商
Petitalot A, Dardillac E, Jacquet E, Nhiri N, Guirouilh Barbat J, Julien P, et al. Combining Homologous Recombination and Phosphopeptide-binding Data to Predict the Impact of BRCA1 BRCT Variants on Cancer Risk. Mol Cancer Res. 2019;17:54-69 pubmed 出版商
Kusmic C, Giorgetti A, Barsanti C, Burchielli S, Petroni D, Kusch A, et al. Spatial Inhomogeneity of Cardiac Norepinephrine Transport Protein and Meta-[123I]Iodobenzylguanidine Uptake in Swine Myocardial Tissue. Mol Imaging Biol. 2019;21:482-490 pubmed 出版商
Esteves S, Oliveira S, Duarte Silva S, Cunha Garcia D, Teixeira Castro A, Maciel P. Preclinical Evidence Supporting Early Initiation of Citalopram Treatment in Machado-Joseph Disease. Mol Neurobiol. 2019;56:3626-3637 pubmed 出版商
Deurloo M, Turlova E, Chen W, Lin Y, Tam E, Tassew N, et al. Transcription Factor 2I Regulates Neuronal Development via TRPC3 in 7q11.23 Disorder Models. Mol Neurobiol. 2019;56:3313-3325 pubmed 出版商
Nixon B, Johnston S, Skerrett Byrne D, Anderson A, Stanger S, Bromfield E, et al. Modification of Crocodile Spermatozoa Refutes the Tenet That Post-testicular Sperm Maturation Is Restricted To Mammals. Mol Cell Proteomics. 2019;18:S59-S76 pubmed 出版商
Avalle L, Camporeale A, Morciano G, Caroccia N, Ghetti E, Orecchia V, et al. STAT3 localizes to the ER, acting as a gatekeeper for ER-mitochondrion Ca2+ fluxes and apoptotic responses. Cell Death Differ. 2019;26:932-942 pubmed 出版商
Ramos Fernández E, Tapia Rojas C, Ramirez V, Inestrosa N. Wnt-7a Stimulates Dendritic Spine Morphogenesis and PSD-95 Expression Through Canonical Signaling. Mol Neurobiol. 2019;56:1870-1882 pubmed 出版商
Carvajal Maldonado D, Byrum A, Jackson J, Wessel S, Lema on D, Guitton Sert L, et al. Perturbing cohesin dynamics drives MRE11 nuclease-dependent replication fork slowing. Nucleic Acids Res. 2019;47:1294-1310 pubmed 出版商
Ortiz Rodriguez A, Acaz Fonseca E, Boya P, Arevalo M, Garcia Segura L. Lipotoxic Effects of Palmitic Acid on Astrocytes Are Associated with Autophagy Impairment. Mol Neurobiol. 2019;56:1665-1680 pubmed 出版商
Finelli M, Paramo T, Pires E, Ryan B, Wade Martins R, Biggin P, et al. Oxidation Resistance 1 Modulates Glycolytic Pathways in the Cerebellum via an Interaction with Glucose-6-Phosphate Isomerase. Mol Neurobiol. 2019;56:1558-1577 pubmed 出版商
Piao X, Miura R, Miyake S, Komazawa Sakon S, Koike M, Shindo R, et al. Blockade of TNF receptor superfamily 1 (TNFR1)-dependent and TNFR1-independent cell death is crucial for normal epidermal differentiation. J Allergy Clin Immunol. 2019;143:213-228.e10 pubmed 出版商
Wang S, Cheng C, Chen C, Chan H, Chen H, Tang P, et al. Acute Heat Stress Changes Protein Expression in the Testes of a Broiler-Type Strain of Taiwan Country Chickens. Anim Biotechnol. 2019;30:129-145 pubmed 出版商
Li G, Zhang W, Gong L, Huang X. MicroRNA 125a-5p Inhibits Cell Proliferation and Induces Apoptosis in Hepatitis B Virus-Related Hepatocellular Carcinoma by Downregulation of ErbB3. Oncol Res. 2019;27:449-458 pubmed 出版商
Szulc Dąbrowska L, Gregorczyk Zboroch K, Struzik J, Wyżewski Z, Ostrowska A, Toka F, et al. Long actin-based cellular protrusions as novel evidence of the cytopathic effect induced in immune cells infected by the ectromelia virus. Cent Eur J Immunol. 2018;43:363-370 pubmed 出版商
Al Azzaz J, Rieu A, Aires V, Delmas D, Chluba J, Winckler P, et al. Resveratrol-Induced Xenophagy Promotes Intracellular Bacteria Clearance in Intestinal Epithelial Cells and Macrophages. Front Immunol. 2018;9:3149 pubmed 出版商
Bellizzi M, Hammond J, Li H, Gantz Marker M, Marker D, Freeman R, et al. The Mixed-Lineage Kinase Inhibitor URMC-099 Protects Hippocampal Synapses in Experimental Autoimmune Encephalomyelitis. Eneuro. 2018;5: pubmed 出版商
de Wit T, Baekelandt V, Lobbestael E. Inhibition of LRRK2 or Casein Kinase 1 Results in LRRK2 Protein Destabilization. Mol Neurobiol. 2018;: pubmed 出版商
Kinouchi K, Magnan C, Ceglia N, Liu Y, Cervantes M, Pastore N, et al. Fasting Imparts a Switch to Alternative Daily Pathways in Liver and Muscle. Cell Rep. 2018;25:3299-3314.e6 pubmed 出版商
Anderson B, Ikeda T, Moghadasi S, Martin A, Brown W, Harris R. Natural APOBEC3C variants can elicit differential HIV-1 restriction activity. Retrovirology. 2018;15:78 pubmed 出版商
Saeki E, Yasuhira S, Shibazaki M, Tada H, Doita M, Masuda T, et al. Involvement of C-terminal truncation mutation of kinesin-5 in resistance to kinesin-5 inhibitor. PLoS ONE. 2018;13:e0209296 pubmed 出版商
Hupalowska A, Jedrusik A, Zhu M, Bedford M, Glover D, Zernicka Goetz M. CARM1 and Paraspeckles Regulate Pre-implantation Mouse Embryo Development. Cell. 2018;175:1902-1916.e13 pubmed 出版商
Su H, Xu X, Yan C, Shi Y, Hu Y, Dong L, et al. LncRNA H19 promotes the proliferation of pulmonary artery smooth muscle cells through AT1R via sponging let-7b in monocrotaline-induced pulmonary arterial hypertension. Respir Res. 2018;19:254 pubmed 出版商
Higo A, Kawashima T, Borg M, Zhao M, Lopez Vidriero I, Sakayama H, et al. Transcription factor DUO1 generated by neo-functionalization is associated with evolution of sperm differentiation in plants. Nat Commun. 2018;9:5283 pubmed 出版商
Durand A, Wiesner T, Gardner M, Robitaille L, Bilodeau A, Gagné C, et al. A machine learning approach for online automated optimization of super-resolution optical microscopy. Nat Commun. 2018;9:5247 pubmed 出版商
Toyama M, Hamaoka Y, Katoh H. EphA3 is up-regulated by epidermal growth factor and promotes formation of glioblastoma cell aggregates. Biochem Biophys Res Commun. 2018;: pubmed 出版商
Fujii R, Komatsu R, Sato T, Seki I, Konomi K, Aono H, et al. SPACIA1/SAAL1 Deletion Results in a Moderate Delay in Collagen-Induced Arthritis Activity, along with mRNA Decay of Cyclin-dependent Kinase 6 Gene. Int J Mol Sci. 2018;19: pubmed 出版商
Sebori R, Kuno A, Hosoda R, Hayashi T, Horio Y. Resveratrol Decreases Oxidative Stress by Restoring Mitophagy and Improves the Pathophysiology of Dystrophin-Deficient mdx Mice. Oxid Med Cell Longev. 2018;2018:9179270 pubmed 出版商
Pettinati I, Grzechnik P, Ribeiro de Almeida C, Brem J, McDonough M, Dhir S, et al. Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease. elife. 2018;7: pubmed 出版商
Li M, Vera N, Yang Y, Zhang B, Ni W, Ziso Qejvanaj E, et al. Adipocyte OGT governs diet-induced hyperphagia and obesity. Nat Commun. 2018;9:5103 pubmed 出版商
Ott C, Federation A, Schwartz L, Kasar S, Klitgaard J, Lenci R, et al. Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia. Cancer Cell. 2018;34:982-995.e7 pubmed 出版商
Hwang J, Park J, Kim M, Kim W, Ha K, Choi B, et al. Isolinderalactone regulates the BCL-2/caspase-3/PARP pathway and suppresses tumor growth in a human glioblastoma multiforme xenograft mouse model. Cancer Lett. 2018;443:25-33 pubmed 出版商
Tse A, Lee A, Takahashi N, Gong A, Kasai H, Tse F. Strong stimulation triggers full fusion exocytosis and very slow endocytosis of the small dense core granules in carotid glomus cells. J Neurogenet. 2018;32:267-278 pubmed 出版商
Kochetkova E, Blinova G, Bystrova O, Martynova M, Pospelov V, Pospelova T. Suppression of mTORC1 activity in senescent Ras-transformed cells neither restores autophagy nor abrogates apoptotic death caused by inhibition of MEK/ERK kinases. Aging (Albany NY). 2018;10:3574-3589 pubmed 出版商
Liu B, Sureda Gómez M, Zhen Y, Amador V, Reverter D. A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25. Nat Commun. 2018;9:4973 pubmed 出版商
Findlay A, Carter R, Starbuck B, McKie L, Nováková K, Budd P, et al. Mouse Idh3a mutations cause retinal degeneration and reduced mitochondrial function. Dis Model Mech. 2018;11: pubmed 出版商
Joseph A, Bhardwaj S, Srivastava L. Role of Prefrontal Cortex Anti- and Pro-inflammatory Cytokines in the Development of Abnormal Behaviors Induced by Disconnection of the Ventral Hippocampus in Neonate Rats. Front Behav Neurosci. 2018;12:244 pubmed 出版商
Durdevic Z, Pillai R, Ephrussi A. Transposon silencing in the Drosophila female germline is essential for genome stability in progeny embryos. Life Sci Alliance. 2018;1:e201800179 pubmed 出版商
Iwakami Y, Yokoyama S, Watanabe K, Hayakawa Y. STAM-binding protein regulates melanoma metastasis through SLUG stabilization. Biochem Biophys Res Commun. 2018;507:484-488 pubmed 出版商
Grohmann M, Wiede F, Dodd G, Gurzov E, Ooi G, Butt T, et al. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. Cell. 2018;175:1289-1306.e20 pubmed 出版商
Decaesteker B, Denecker G, Van Neste C, Dolman E, Van Loocke W, Gartlgruber M, et al. TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets. Nat Commun. 2018;9:4866 pubmed 出版商
Liu C, Lou W, Yang J, Liu L, Armstrong C, Lombard A, et al. Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer. Nat Commun. 2018;9:4700 pubmed 出版商
Huang W, Chong I, Chen H, Li C, Hsieh C, Kuo H, et al. Pigment epithelium-derived factor inhibits lung cancer migration and invasion by upregulating exosomal thrombospondin 1. Cancer Lett. 2018;442:287-298 pubmed 出版商
Sheng J, Zhao Q, Zhao J, Zhang W, Sun Y, Qin P, et al. SRSF1 modulates PTPMT1 alternative splicing to regulate lung cancer cell radioresistance. EBioMedicine. 2018;38:113-126 pubmed 出版商
Bejarano D, Puertas M, Börner K, Martinez Picado J, Muller B, Kräusslich H. Detailed Characterization of Early HIV-1 Replication Dynamics in Primary Human Macrophages. Viruses. 2018;10: pubmed 出版商
Bonath F, Domingo Prim J, Tarbier M, Friedländer M, Visa N. Next-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks. Nucleic Acids Res. 2018;46:11869-11882 pubmed 出版商
Chen Y, Liu Y, Liu Y, Lee Y, Huang H, Chen Y, et al. Nitrite protects neurons against hypoxic damage through <i>S</i>-nitrosylation of caspase-6. Antioxid Redox Signal. 2018;: pubmed 出版商
Pereira C, Reis R, Gama J, Celestino R, Cheerambathur D, Carvalho A, et al. Self-Assembly of the RZZ Complex into Filaments Drives Kinetochore Expansion in the Absence of Microtubule Attachment. Curr Biol. 2018;28:3408-3421.e8 pubmed 出版商
Ho D, Kim H, Nam D, Sim H, Kim J, Kim H, et al. LRRK2 impairs autophagy by mediating phosphorylation of leucyl-tRNA synthetase. Cell Biochem Funct. 2018;36:431-442 pubmed 出版商
Firkowska M, Macias M, Jaworski J. ESCRT Proteins Control the Dendritic Morphology of Developing and Mature Hippocampal Neurons. Mol Neurobiol. 2018;: pubmed 出版商
Yoshida J, Abe H, Watanabe T, Kawada M. Intervenolin suppresses gastric cancer cell growth through the induction of TSP-1 secretion from fibroblast-like stromal cells. Oncol Lett. 2018;16:6777-6785 pubmed 出版商
Franco Iborra S, Cuadros T, Parent A, Romero Gimenez J, Vila M, Perier C. Defective mitochondrial protein import contributes to complex I-induced mitochondrial dysfunction and neurodegeneration in Parkinson's disease. Cell Death Dis. 2018;9:1122 pubmed 出版商
Shakya S, Sharma P, Bhatt A, Jani R, Delevoye C, Setty S. Rab22A recruits BLOC-1 and BLOC-2 to promote the biogenesis of recycling endosomes. EMBO Rep. 2018;19: pubmed 出版商
Vissers J, Froldi F, Schröder J, Papenfuss A, Cheng L, Harvey K. The Scalloped and Nerfin-1 Transcription Factors Cooperate to Maintain Neuronal Cell Fate. Cell Rep. 2018;25:1561-1576.e7 pubmed 出版商
Danhauser K, Alhaddad B, Makowski C, Piekutowska Abramczuk D, Syrbe S, Gomez Ospina N, et al. Bi-allelic ADPRHL2 Mutations Cause Neurodegeneration with Developmental Delay, Ataxia, and Axonal Neuropathy. Am J Hum Genet. 2018;103:817-825 pubmed 出版商
Kim S, Woo C. Laminar Flow Inhibits ER Stress-Induced Endothelial Apoptosis through PI3K/Akt-Dependent Signaling Pathway. Mol Cells. 2018;41:964-970 pubmed 出版商
Hamoud N, Tran V, Aimi T, Kakegawa W, Lahaie S, Thibault M, et al. Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion. Nat Commun. 2018;9:4470 pubmed 出版商
Yoo T, Cho H, Lee J, Park H, Yoo Y, Yang E, et al. GABA Neuronal Deletion of Shank3 Exons 14-16 in Mice Suppresses Striatal Excitatory Synaptic Input and Induces Social and Locomotor Abnormalities. Front Cell Neurosci. 2018;12:341 pubmed 出版商
Bayo J, Tran T, Wang L, Peña Llopis S, Das A, Martinez E. Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks. Cell Rep. 2018;25:1040-1050.e5 pubmed 出版商
Bärenz F, Kschonsak Y, Meyer A, Jafarpour A, Lorenz H, Hoffmann I. Ccdc61 controls centrosomal localization of Cep170 and is required for spindle assembly and symmetry. Mol Biol Cell. 2018;:mbcE18020115 pubmed 出版商
Kim J, Piao H, Kim B, Yao F, Han Z, Wang Y, et al. Long noncoding RNA MALAT1 suppresses breast cancer metastasis. Nat Genet. 2018;50:1705-1715 pubmed 出版商
Kuno A, Hosoda R, Sebori R, Hayashi T, Sakuragi H, Tanabe M, et al. Resveratrol Ameliorates Mitophagy Disturbance and Improves Cardiac Pathophysiology of Dystrophin-deficient mdx Mice. Sci Rep. 2018;8:15555 pubmed 出版商
Humphry N, Wheatley S. Survivin inhibits excessive autophagy in cancer cells but does so independently of its interaction with LC3. Biol Open. 2018;7: pubmed 出版商
Larochelle M, Robert M, Hébert J, Liu X, Matteau D, Rodrigue S, et al. Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast. Nat Commun. 2018;9:4364 pubmed 出版商
Rizzo M, Beffy P, Del Carratore R, Falleni A, Pretini V, D Aurizio R, et al. Activation of the interferon type I response rather than autophagy contributes to myogenesis inhibition in congenital DM1 myoblasts. Cell Death Dis. 2018;9:1071 pubmed 出版商
Fujibayashi E, Yabuta N, Nishikawa Y, Uchihashi T, Miura D, Kurioka K, et al. Isolation of cancer cells with augmented spheroid-forming capability using a novel tool equipped with removable filter. Oncotarget. 2018;9:33931-33946 pubmed 出版商
Murata H, Khine C, Nishikawa A, Yamamoto K, Kinoshita R, Sakaguchi M. c-Jun N-terminal kinase (JNK)-mediated phosphorylation of SARM1 regulates NAD+ cleavage activity to inhibit mitochondrial respiration. J Biol Chem. 2018;293:18933-18943 pubmed 出版商
Zhang H, Zhang C, Vincent J, Zala D, Benstaali C, Sainlos M, et al. Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington's disease models. Nat Commun. 2018;9:4272 pubmed 出版商
Moreau P, Cournac A, Palumbo G, Marbouty M, Mortaza S, Thierry A, et al. Tridimensional infiltration of DNA viruses into the host genome shows preferential contact with active chromatin. Nat Commun. 2018;9:4268 pubmed 出版商
Ceyzériat K, Ben Haim L, Denizot A, Pommier D, Matos M, Guillemaud O, et al. Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer's disease. Acta Neuropathol Commun. 2018;6:104 pubmed 出版商
Telekawa C, Boisvert F, Bachand F. Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome. Nucleic Acids Res. 2018;46:11169-11183 pubmed 出版商
Janssen A, Katrukha E, van Straaten W, Verlhac P, Reggiori F, Kapitein L. Probing aggrephagy using chemically-induced protein aggregates. Nat Commun. 2018;9:4245 pubmed 出版商
González García I, CONTRERAS C, Estévez Salguero Á, Ruiz Pino F, Colsh B, Pensado I, et al. Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress. Cell Rep. 2018;25:413-423.e5 pubmed 出版商
Boutchueng Djidjou M, Belleau P, Bilodeau N, Fortier S, Bourassa S, Droit A, et al. A type 2 diabetes disease module with a high collective influence for Cdk2 and PTPLAD1 is localized in endosomes. PLoS ONE. 2018;13:e0205180 pubmed 出版商
Malcher J, Heidt L, Goyenvalle A, Escobar H, Marg A, Beley C, et al. Exon Skipping in a Dysf-Missense Mutant Mouse Model. Mol Ther Nucleic Acids. 2018;13:198-207 pubmed 出版商
Sagredo E, Blanco A, Sagredo A, Perez P, Sepúlveda Hermosilla G, Morales F, et al. ADAR1-mediated RNA-editing of 3'UTRs in breast cancer. Biol Res. 2018;51:36 pubmed 出版商
Vink E, Lee S, Smiley J, Mohr I. Remodeling mTORC1 Responsiveness to Amino Acids by the Herpes Simplex Virus UL46 and Us3 Gene Products Supports Replication during Nutrient Insufficiency. J Virol. 2018;92: pubmed 出版商
Liu D, Carter N, Wu X, Hong W, Chen S, Zhu Y. Progestin and Nuclear Progestin Receptor Are Essential for Upregulation of Metalloproteinase in Zebrafish Preovulatory Follicles. Front Endocrinol (Lausanne). 2018;9:517 pubmed 出版商
Arora S, Heyza J, Chalfin E, Ruch R, Patrick S. Gap Junction Intercellular Communication Positively Regulates Cisplatin Toxicity by Inducing DNA Damage through Bystander Signaling. Cancers (Basel). 2018;10: pubmed 出版商
Munkley J, Maia T, Ibarluzea N, Livermore K, Vodák D, Ehrmann I, et al. Androgen-dependent alternative mRNA isoform expression in prostate cancer cells. F1000Res. 2018;7:1189 pubmed 出版商
Deguchi Y, Nishina T, Asano K, Ohmuraya M, Nakagawa Y, Nakagata N, et al. Generation of and characterization of anti-IL-11 antibodies using newly established Il11-deficient mice. Biochem Biophys Res Commun. 2018;505:453-459 pubmed 出版商
Hsieh H, Zhang W, Lin S, Yang W, Wang J, Shen J, et al. Systems biology approach reveals a link between mTORC1 and G2/M DNA damage checkpoint recovery. Nat Commun. 2018;9:3982 pubmed 出版商
Wang J, Wang Z, Li M, Zhang Z, Mi C, Zuo H, et al. Dictamnine promotes apoptosis and inhibits epithelial-mesenchymal transition, migration, invasion and proliferation by downregulating the HIF-1α and Slug signaling pathways. Chem Biol Interact. 2018;296:134-144 pubmed 出版商
Wang L, Failler M, Fu W, Dynlacht B. A distal centriolar protein network controls organelle maturation and asymmetry. Nat Commun. 2018;9:3938 pubmed 出版商
Zhang G, Tu S, Yu T, Zhang X, Parhad S, Weng Z, et al. Co-dependent Assembly of Drosophila piRNA Precursor Complexes and piRNA Cluster Heterochromatin. Cell Rep. 2018;24:3413-3422.e4 pubmed 出版商
Dai J, Zhou Q, Chen J, Rexius Hall M, Rehman J, Zhou G. Alpha-enolase regulates the malignant phenotype of pulmonary artery smooth muscle cells via the AMPK-Akt pathway. Nat Commun. 2018;9:3850 pubmed 出版商
Chatterjee A, Rodger E, Ahn A, Stockwell P, Parry M, Motwani J, et al. Marked Global DNA Hypomethylation Is Associated with Constitutive PD-L1 Expression in Melanoma. iScience. 2018;4:312-325 pubmed 出版商
Parrish J, McCann T, Sechler M, Sobral L, Ren W, Jones K, et al. The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth. Oncotarget. 2018;9:33110-33123 pubmed 出版商
Hinchy E, Gruszczyk A, Willows R, Navaratnam N, Hall A, Bates G, et al. Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly. J Biol Chem. 2018;293:17208-17217 pubmed 出版商
Traeger L, Gallitz I, Sekhri R, Baumer N, Kuhlmann T, Kemming C, et al. ALK3 undergoes ligand-independent homodimerization and BMP-induced heterodimerization with ALK2. Free Radic Biol Med. 2018;129:127-137 pubmed 出版商
Zulato E, Ciccarese F, Agnusdei V, Pinazza M, Nardo G, Iorio E, et al. LKB1 loss is associated with glutathione deficiency under oxidative stress and sensitivity of cancer cells to cytotoxic drugs and γ-irradiation. Biochem Pharmacol. 2018;156:479-490 pubmed 出版商
Kim J, Garcia Carbonell R, Yamachika S, Zhao P, Dhar D, Loomba R, et al. ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P. Cell. 2018;175:133-145.e15 pubmed 出版商
Lesbirel S, Viphakone N, Parker M, Parker J, Heath C, Sudbery I, et al. The m6A-methylase complex recruits TREX and regulates mRNA export. Sci Rep. 2018;8:13827 pubmed 出版商
Mouly L, Mamouni K, Gence R, Cristini A, Cherier J, Castinel A, et al. PARP-1-dependent RND1 transcription induced by topoisomerase I cleavage complexes confers cellular resistance to camptothecin. Cell Death Dis. 2018;9:931 pubmed 出版商
Xu Y, Luo X, Fang Z, Zheng X, Zeng Y, Zhu C, et al. Transcription coactivator Cited1 acts as an inducer of trophoblast-like state from mouse embryonic stem cells through the activation of BMP signaling. Cell Death Dis. 2018;9:924 pubmed 出版商
Luhtala N, Hunter T. Failure to detect functional transfer of active K-Ras protein from extracellular vesicles into recipient cells in culture. PLoS ONE. 2018;13:e0203290 pubmed 出版商
Cara F, Bülow M, Simmonds A, Rachubinski R. Dysfunctional peroxisomes compromise gut structure and host defense by increased cell death and Tor-dependent autophagy. Mol Biol Cell. 2018;29:2766-2783 pubmed 出版商
Abbasi F, Miyata H, Shimada K, Morohoshi A, Nozawa K, Matsumura T, et al. RSPH6A is required for sperm flagellum formation and male fertility in mice. J Cell Sci. 2018;131: pubmed 出版商
van den Berg J, G Manjón A, Kielbassa K, Feringa F, Freire R, Medema R. A limited number of double-strand DNA breaks is sufficient to delay cell cycle progression. Nucleic Acids Res. 2018;46:10132-10144 pubmed 出版商
Mi C, Wang Z, Li M, Zhang Z, Ma J, Jin X. Zinc finger protein 91 positively regulates the production of IL-1β in macrophages by activation of MAPKs and non-canonical caspase-8 inflammasome. Br J Pharmacol. 2018;175:4338-4352 pubmed 出版商
Choppara S, Ganga S, Manne R, Dutta P, Singh S, Santra M. The SCFFBXO46 ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence. J Biol Chem. 2018;293:16291-16306 pubmed 出版商
Scheri K, Leonetti E, Laino L, Gigantino V, Gesualdi L, Grammatico P, et al. c-MET receptor as potential biomarker and target molecule for malignant testicular germ cell tumors. Oncotarget. 2018;9:31842-31860 pubmed 出版商
Xu X, Tan X, Tampe B, Wilhelmi T, Hulshoff M, Saito S, et al. High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis. Nat Commun. 2018;9:3509 pubmed 出版商
Hirashima T, Tanaka R, Yamaguchi M, Yoshida H. The ABD on the nascent polypeptide and PH domain are required for the precise Anillin localization in Drosophila syncytial blastoderm. Sci Rep. 2018;8:12910 pubmed 出版商
Ganguly A, Guo L, Sun L, Suo F, Du L, Russell P. Tdp1 processes chromate-induced single-strand DNA breaks that collapse replication forks. PLoS Genet. 2018;14:e1007595 pubmed 出版商
Sarmento M, Oneto M, Pelicci S, Pesce L, Scipioni L, Faretta M, et al. Exploiting the tunability of stimulated emission depletion microscopy for super-resolution imaging of nuclear structures. Nat Commun. 2018;9:3415 pubmed 出版商
Tarade D, Robinson C, Lee J, Ohh M. HIF-2α-pVHL complex reveals broad genotype-phenotype correlations in HIF-2α-driven disease. Nat Commun. 2018;9:3359 pubmed 出版商
Demine S, Balhuizen A, Debaille V, Joosten L, Fereau M, Chilla S, et al. Imaging of Human Insulin Secreting Cells with Gd-DOTA-P88, a Paramagnetic Contrast Agent Targeting the Beta Cell Biomarker FXYD2γa. Molecules. 2018;23: pubmed 出版商
Furuya T, Hattori K, Kimori Y, Ishida S, Nishihama R, Kohchi T, et al. ANGUSTIFOLIA contributes to the regulation of three-dimensional morphogenesis in the liverwort Marchantia polymorpha. Development. 2018;145: pubmed 出版商
Morita K, Yamamoto Y, Hori A, Obata T, Uno Y, Shinohara K, et al. Expression, Functional Characterization, and Preliminary Crystallization of the Cochaperone Prefoldin from the Thermophilic Fungus Chaetomium thermophilum. Int J Mol Sci. 2018;19: pubmed 出版商
Janssen L, Averink T, Blomen V, Brummelkamp T, Medema R, Raaijmakers J. Loss of Kif18A Results in Spindle Assembly Checkpoint Activation at Microtubule-Attached Kinetochores. Curr Biol. 2018;28:2685-2696.e4 pubmed 出版商
Daniel K, Icha J, Horenburg C, Müller D, Norden C, Mansfeld J. Conditional control of fluorescent protein degradation by an auxin-dependent nanobody. Nat Commun. 2018;9:3297 pubmed 出版商
Zhou P, She Y, Dong N, Li P, He H, Borio A, et al. Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose. Nature. 2018;561:122-126 pubmed 出版商
Jin Y, Cong Q, Gvozdenovic Jeremic J, Hu J, Zhang Y, Terkeltaub R, et al. Enpp1 inhibits ectopic joint calcification and maintains articular chondrocytes by repressing hedgehog signaling. Development. 2018;145: pubmed 出版商
Lazaro I, Lopez Sanz L, Bernal S, Oguiza A, Recio C, Melgar A, et al. Nrf2 Activation Provides Atheroprotection in Diabetic Mice Through Concerted Upregulation of Antioxidant, Anti-inflammatory, and Autophagy Mechanisms. Front Pharmacol. 2018;9:819 pubmed 出版商
Jung H, Park H, Choi Y, Kang H, Lee E, Kweon H, et al. Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice. Nat Neurosci. 2018;21:1218-1228 pubmed 出版商
Mandemaker I, Geijer M, Kik I, Bezstarosti K, Rijkers E, Raams A, et al. DNA damage-induced replication stress results in PA200-proteasome-mediated degradation of acetylated histones. EMBO Rep. 2018;19: pubmed 出版商
Xu G, Li T, Chen J, Li C, Zhao H, Yao C, et al. Autosomal dominant retinitis pigmentosa-associated gene PRPF8 is essential for hypoxia-induced mitophagy through regulating ULK1 mRNA splicing. Autophagy. 2018;14:1818-1830 pubmed 出版商
Xing Y, Mi C, Wang Z, Zhang Z, Li M, Zuo H, et al. Fraxinellone has anticancer activity in vivo by inhibiting programmed cell death-ligand 1 expression by reducing hypoxia-inducible factor-1α and STAT3. Pharmacol Res. 2018;135:166-180 pubmed 出版商
Liu Y, Zou W, Yang P, Wang L, Ma Y, Zhang H, et al. Autophagy-dependent ribosomal RNA degradation is essential for maintaining nucleotide homeostasis during C. elegans development. elife. 2018;7: pubmed 出版商
Piras A, Burrai G, Ariu F, Falchi L, Zedda M, Pau S, et al. Structure of preantral follicles, oxidative status and developmental competence of in vitro matured oocytes after ovary storage at 4 °C in the domestic cat model. Reprod Biol Endocrinol. 2018;16:76 pubmed 出版商
Dai J, Zhou Q, Tang H, Chen T, Li J, Raychaudhuri P, et al. Smooth muscle cell-specific FoxM1 controls hypoxia-induced pulmonary hypertension. Cell Signal. 2018;51:119-129 pubmed 出版商
Matsumoto R, Dainichi T, Tsuchiya S, Nomura T, Kitoh A, Hayden M, et al. Epithelial TRAF6 drives IL-17-mediated psoriatic inflammation. JCI Insight. 2018;3: pubmed 出版商
Abe T, Kawasumi R, Giannattasio M, Dusi S, Yoshimoto Y, Miyata K, et al. AND-1 fork protection function prevents fork resection and is essential for proliferation. Nat Commun. 2018;9:3091 pubmed 出版商
Zhang X, Patel D, Xu Q, VEENSTRA R. Differences in Functional Expression of Connexin43 and NaV1.5 by Pan- and Class-Selective Histone Deacetylase Inhibition in Heart. Int J Mol Sci. 2018;19: pubmed 出版商
Vuong T, Rønning S, Ahmed T, Brathagen K, Høst V, Hincke M, et al. Processed eggshell membrane powder regulates cellular functions and increase MMP-activity important in early wound healing processes. PLoS ONE. 2018;13:e0201975 pubmed 出版商
Wu L, Cao J, Cai W, Lang S, Horton J, Jansen D, et al. KDM5 histone demethylases repress immune response via suppression of STING. PLoS Biol. 2018;16:e2006134 pubmed 出版商
Novais Cruz M, Alba Abad M, van IJcken W, Galjart N, Jeyaprakash A, Maiato H, et al. Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription. elife. 2018;7: pubmed 出版商
Frick P, Sellier C, Mackenzie I, Cheng C, Tahraoui Bories J, Martinat C, et al. Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers. Acta Neuropathol Commun. 2018;6:72 pubmed 出版商
Stonyte V, Boye E, Grallert B. Regulation of global translation during the cell cycle. J Cell Sci. 2018;131: pubmed 出版商
Canato S, Santos J, Carvalho A, Aloria K, Amaral M, Matthiesen R, et al. Proteomic interaction profiling reveals KIFC1 as a factor involved in early targeting of F508del-CFTR to degradation. Cell Mol Life Sci. 2018;75:4495-4509 pubmed 出版商
Li G, Huang S, Yang S, Wang J, Cao J, Czajkowsky D, et al. abLIM1 constructs non-erythroid cortical actin networks to prevent mechanical tension-induced blebbing. Cell Discov. 2018;4:42 pubmed 出版商
Krzyzosiak A, Sigurdardottir A, Luh L, Carrara M, Das I, Schneider K, et al. Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B. Cell. 2018;174:1216-1228.e19 pubmed 出版商
Kumar A, Daitsh Y, Ben Aderet L, Qiq O, Elayyan J, Batshon G, et al. A predicted unstructured C-terminal loop domain in SIRT1 is required for cathepsin B cleavage. J Cell Sci. 2018;131: pubmed 出版商
Bristol J, Djavadian R, Albright E, Coleman C, Ohashi M, Hayes M, et al. A cancer-associated Epstein-Barr virus BZLF1 promoter variant enhances lytic infection. PLoS Pathog. 2018;14:e1007179 pubmed 出版商
Welch S, Scholte F, Albarino C, Kainulainen M, Coleman McCray J, Guerrero L, et al. The S Genome Segment Is Sufficient to Maintain Pathogenicity in Intra-Clade Lassa Virus Reassortants in a Guinea Pig Model. Front Cell Infect Microbiol. 2018;8:240 pubmed 出版商
Muñoz B, Yevenes G, Förstera B, Lovinger D, Aguayo L. Presence of Inhibitory Glycinergic Transmission in Medium Spiny Neurons in the Nucleus Accumbens. Front Mol Neurosci. 2018;11:228 pubmed 出版商
Dhir A, Dhir S, Borowski L, Jimenez L, Teitell M, Rotig A, et al. Mitochondrial double-stranded RNA triggers antiviral signalling in humans. Nature. 2018;560:238-242 pubmed 出版商
Zhong Z, Liang S, Sanchez Lopez E, He F, Shalapour S, Lin X, et al. New mitochondrial DNA synthesis enables NLRP3 inflammasome activation. Nature. 2018;560:198-203 pubmed 出版商
Cunha Ferreira I, Chazeau A, Buijs R, Stucchi R, Will L, Pan X, et al. The HAUS Complex Is a Key Regulator of Non-centrosomal Microtubule Organization during Neuronal Development. Cell Rep. 2018;24:791-800 pubmed 出版商
Qian K, Wang S, Fu M, Zhou J, Singh J, Li M, et al. Transcriptional regulation of O-GlcNAc homeostasis is disrupted in pancreatic cancer. J Biol Chem. 2018;293:13989-14000 pubmed 出版商
Seidel H, Smith T, Evans J, Stamper J, Mast T, Kimble J. C. elegans germ cells divide and differentiate in a folded tissue. Dev Biol. 2018;442:173-187 pubmed 出版商
Chernick D, Ortiz Valle S, Jeong A, Swaminathan S, Kandimalla K, Rebeck G, et al. High-density lipoprotein mimetic peptide 4F mitigates amyloid-β-induced inhibition of apolipoprotein E secretion and lipidation in primary astrocytes and microglia. J Neurochem. 2018;147:647-662 pubmed 出版商
Macedo J, Vaz S, Bakker B, Ribeiro R, Bakker P, Escandell J, et al. FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence. Nat Commun. 2018;9:2834 pubmed 出版商
Kahn O, Schätzle P, van de Willige D, Tas R, Lindhout F, Portegies S, et al. APC2 controls dendrite development by promoting microtubule dynamics. Nat Commun. 2018;9:2773 pubmed 出版商
Liñares Pose L, Rial Pensado E, Estévez Salguero Á, Milbank E, González García I, Rodriguez C, et al. Genetic Targeting of GRP78 in the VMH Improves Obesity Independently of Food Intake. Genes (Basel). 2018;9: pubmed 出版商
Shen M, Cao Y, Jiang Y, Wei Y, Liu H. Melatonin protects mouse granulosa cells against oxidative damage by inhibiting FOXO1-mediated autophagy: Implication of an antioxidation-independent mechanism. Redox Biol. 2018;18:138-157 pubmed 出版商
Zhang Z, Krauchunas A, Huang S, Wolfner M. Maternal Proteins That Are Phosphoregulated upon Egg Activation Include Crucial Factors for Oogenesis, Egg Activation and Embryogenesis in Drosophila melanogaster. G3 (Bethesda). 2018;8:3005-3018 pubmed 出版商
Li D, Tian G, Wang J, Zhao L, Co O, Underill Z, et al. Inhibition of androgen receptor transactivation function by adenovirus type 12 E1A undermines prostate cancer cell survival. Prostate. 2018;78:1140-1156 pubmed 出版商
Zhan N, Wang C, Chen L, Yang H, Feng J, Gong X, et al. S-Nitrosylation Targets GSNO Reductase for Selective Autophagy during Hypoxia Responses in Plants. Mol Cell. 2018;71:142-154.e6 pubmed 出版商
Collins C, Malacrida B, Burke C, Kiely P, Dunleavy E. ATP synthase F1 subunits recruited to centromeres by CENP-A are required for male meiosis. Nat Commun. 2018;9:2702 pubmed 出版商
Li X, Zhang Y, Zheng L, Liu M, Chen C, Jiang H. UTX is an escape from X-inactivation tumor-suppressor in B cell lymphoma. Nat Commun. 2018;9:2720 pubmed 出版商
Gao P, Wu W, Ye J, Lu Y, Adam A, Singer H, et al. Transforming growth factor β1 suppresses proinflammatory gene program independent of its regulation on vascular smooth muscle differentiation and autophagy. Cell Signal. 2018;50:160-170 pubmed 出版商
Tokuo H, Bhawan J, Coluccio L. Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis. Sci Rep. 2018;8:10449 pubmed 出版商
Kumar N, Prasad P, Jash E, Jayasundar S, Singh I, Alam N, et al. cAMP regulated EPAC1 supports microvascular density, angiogenic and metastatic properties in a model of triple negative breast cancer. Carcinogenesis. 2018;39:1245-1253 pubmed 出版商
McDermott J, Goldblatt D, Paradis S. Class 4 Semaphorins and Plexin-B receptors regulate GABAergic and glutamatergic synapse development in the mammalian hippocampus. Mol Cell Neurosci. 2018;92:50-66 pubmed 出版商
Pavlaki I, Docquier F, Chernukhin I, Kita G, Gretton S, Clarkson C, et al. Poly(ADP-ribosyl)ation associated changes in CTCF-chromatin binding and gene expression in breast cells. Biochim Biophys Acta Gene Regul Mech. 2018;1861:718-730 pubmed 出版商
Martín A, Gómez SanMiguel A, Priego T, López Calderón A. Formoterol treatment prevents the effects of endotoxin on muscle TNF/NF-kB, Akt/mTOR, and proteolytic pathways in a rat model. Role of IGF-I and miRNA 29b. Am J Physiol Endocrinol Metab. 2018;315:E705-E714 pubmed 出版商
Tamai M, Inukai T, Kojika S, Abe M, Kagami K, Harama D, et al. T315I mutation of BCR-ABL1 into human Philadelphia chromosome-positive leukemia cell lines by homologous recombination using the CRISPR/Cas9 system. Sci Rep. 2018;8:9966 pubmed 出版商
Blache U, Vallmajo Martin Q, Horton E, Guerrero J, Djonov V, Scherberich A, et al. Notch-inducing hydrogels reveal a perivascular switch of mesenchymal stem cell fate. EMBO Rep. 2018;19: pubmed 出版商
Rauch A, Carlstedt A, Emmerich C, Mustafa A, Göder A, Knauer S, et al. Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cells. Oncotarget. 2018;9:27835-27850 pubmed 出版商
Santos E, Silva M, Amorim R, Giordano L, Silva D, Rasmussen L, et al. Aging and chromatoid body assembly: Are these two physiological events linked?. Exp Biol Med (Maywood). 2018;243:917-925 pubmed 出版商
Barutcu S, Girnius N, Vernia S, Davis R. Role of the MAPK/cJun NH2-terminal kinase signaling pathway in starvation-induced autophagy. Autophagy. 2018;14:1586-1595 pubmed 出版商
Jayson C, Arlt H, Fischer A, Lai Z, Farese R, Walther T. Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells. Mol Biol Cell. 2018;29:2045-2054 pubmed 出版商
Chen Y, Huang Q, Liu W, Zhu Q, Cui C, Xu L, et al. Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth. Nat Commun. 2018;9:2464 pubmed 出版商
Mauthe M, Orhon I, Rocchi C, Zhou X, Luhr M, Hijlkema K, et al. Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion. Autophagy. 2018;14:1435-1455 pubmed 出版商
Murakami T, Kim J, Li Y, Green G, Shikanov A, Ono A. Secondary lymphoid organ fibroblastic reticular cells mediate trans-infection of HIV-1 via CD44-hyaluronan interactions. Nat Commun. 2018;9:2436 pubmed 出版商
Ivanov M, Ladurner R, Poser I, Beveridge R, Rampler E, Hudecz O, et al. The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion. EMBO J. 2018;37: pubmed 出版商
Viau A, Bienaime F, Lukas K, Todkar A, Knoll M, Yakulov T, et al. Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney. EMBO J. 2018;37: pubmed 出版商
Sasaki Y, Hackett A, Kim S, Strickland A, Milbrandt J. Dysregulation of NAD+ Metabolism Induces a Schwann Cell Dedifferentiation Program. J Neurosci. 2018;38:6546-6562 pubmed 出版商
Pallavicini G, Sgrò F, Garello F, Falcone M, Bitonto V, Berto G, et al. Inactivation of Citron Kinase Inhibits Medulloblastoma Progression by Inducing Apoptosis and Cell Senescence. Cancer Res. 2018;78:4599-4612 pubmed 出版商
Murillo de Ozores A, Rodríguez Gama A, Bazúa Valenti S, Leyva Ríos K, Vazquez N, Pacheco Alvarez D, et al. C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity. J Biol Chem. 2018;293:12209-12221 pubmed 出版商
Sun J, Guo Y, Zhang Q, Bu S, Li B, Wang Q, et al. Chronic restraint stress disturbs meiotic resumption through APC/C-mediated cyclin B1 excessive degradation in mouse oocytes. Cell Cycle. 2018;17:1591-1601 pubmed 出版商
Thongrod S, Wanichanon C, Kankuan W, Siangcham T, Phadngam S, Morani F, et al. Autophagy-Associated Shrinkage of the Hepatopancreas in Fasting Male Macrobrachium rosenbergii Is Rescued by Neuropeptide F. Front Physiol. 2018;9:613 pubmed 出版商
Kim S, Knight D, Jones L, Vervoort S, Ng A, Seymour J, et al. JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias. Genes Dev. 2018;32:849-864 pubmed 出版商
Parua P, Booth G, Sansó M, Benjamin B, Tanny J, Lis J, et al. A Cdk9-PP1 switch regulates the elongation-termination transition of RNA polymerase II. Nature. 2018;558:460-464 pubmed 出版商
Marcassa E, Kallinos A, Jardine J, Rusilowicz Jones E, Martinez A, Kuehl S, et al. Dual role of USP30 in controlling basal pexophagy and mitophagy. EMBO Rep. 2018;19: pubmed 出版商
Dhar D, Antonucci L, Nakagawa H, Kim J, Glitzner E, Caruso S, et al. Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling. Cancer Cell. 2018;33:1061-1077.e6 pubmed 出版商
Yao F, Zhou Z, Kim J, Hang Q, Xiao Z, Ton B, et al. SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity. Nat Commun. 2018;9:2269 pubmed 出版商
Macdonald E, Brown L, Selvais A, Liu H, WARING T, Newman D, et al. HRS-WASH axis governs actin-mediated endosomal recycling and cell invasion. J Cell Biol. 2018;217:2549-2564 pubmed 出版商
Lombard A, Liu L, Cucchiara V, Liu C, Armstrong C, Zhao R, et al. Intra versus Inter Cross-resistance Determines Treatment Sequence between Taxane and AR-Targeting Therapies in Advanced Prostate Cancer. Mol Cancer Ther. 2018;17:2197-2205 pubmed 出版商
Chopard C, Tong P, Tóth P, Schatz M, Yezid H, Debaisieux S, et al. Cyclophilin A enables specific HIV-1 Tat palmitoylation and accumulation in uninfected cells. Nat Commun. 2018;9:2251 pubmed 出版商
Jatana S, Homer C, Madajka M, Ponti A, Kabi A, Papay F, et al. Pyrimidine synthesis inhibition enhances cutaneous defenses against antibiotic resistant bacteria through activation of NOD2 signaling. Sci Rep. 2018;8:8708 pubmed 出版商
Blount J, Libohova K, Marsh G, Sutton J, Todi S. Expression and Regulation of Deubiquitinase-Resistant, Unanchored Ubiquitin Chains in Drosophila. Sci Rep. 2018;8:8513 pubmed 出版商
Limbo O, Yamada Y, Russell P. Mre11-Rad50-dependent activity of ATM/Tel1 at DNA breaks and telomeres in the absence of Nbs1. Mol Biol Cell. 2018;29:1389-1399 pubmed 出版商
Kalem M, Gerasimov E, Vu P, Zimmer S. Gene expression to mitochondrial metabolism: Variability among cultured Trypanosoma cruzi strains. PLoS ONE. 2018;13:e0197983 pubmed 出版商
Nath S, Yu Z, Gipson T, Marsh G, Yoshidome E, Robins D, et al. Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. J Clin Invest. 2018;128:3630-3641 pubmed 出版商
Menon T, Nair S. Transient window of resilience during early development minimizes teratogenic effects of heat in zebrafish embryos. Dev Dyn. 2018;247:992-1004 pubmed 出版商
Turakhiya A, Meyer S, Marincola G, Böhm S, Vanselow J, Schlosser A, et al. ZFAND1 Recruits p97 and the 26S Proteasome to Promote the Clearance of Arsenite-Induced Stress Granules. Mol Cell. 2018;70:906-919.e7 pubmed 出版商
Ferreira L, Figueiredo A, Orr B, Lopes D, Maiato H. Dissecting the role of the tubulin code in mitosis. Methods Cell Biol. 2018;144:33-74 pubmed 出版商
Li Y, Kim R, Cho Y, Song W, Kim D, Kim K, et al. Lrfn2-Mutant Mice Display Suppressed Synaptic Plasticity and Inhibitory Synapse Development and Abnormal Social Communication and Startle Response. J Neurosci. 2018;38:5872-5887 pubmed 出版商
Xiao Y, Wang C, Chen J, Lu F, Wang J, Hou N, et al. Deficiency of PRKD2 triggers hyperinsulinemia and metabolic disorders. Nat Commun. 2018;9:2015 pubmed 出版商
Tomida J, Takata K, Bhetawal S, Person M, Chao H, Tang D, et al. FAM35A associates with REV7 and modulates DNA damage responses of normal and BRCA1-defective cells. EMBO J. 2018;37: pubmed 出版商
Habtemichael E, Li D, Alcazar Roman A, Westergaard X, Li M, Petersen M, et al. Usp25m protease regulates ubiquitin-like processing of TUG proteins to control GLUT4 glucose transporter translocation in adipocytes. J Biol Chem. 2018;293:10466-10486 pubmed 出版商
Dong Z, Zhu C, Zhan Q, Jiang W. Cdk phosphorylation licenses Kif4A chromosome localization required for early mitotic progression. J Mol Cell Biol. 2018;10:358-370 pubmed 出版商
Münch J, Billig G, Hübner C, Leinders Zufall T, Zufall F, Jentsch T. Ca2+-activated Cl- currents in the murine vomeronasal organ enhance neuronal spiking but are dispensable for male-male aggression. J Biol Chem. 2018;293:10392-10403 pubmed 出版商
Gonçalves S, Patat J, Guida M, Lachaussée N, Arrondel C, Helmstädter M, et al. A homozygous KAT2B variant modulates the clinical phenotype of ADD3 deficiency in humans and flies. PLoS Genet. 2018;14:e1007386 pubmed 出版商
Miyazaki M, Otomo R, Matsushima Hibiya Y, Suzuki H, Nakajima A, Abe N, et al. The p53 activator overcomes resistance to ALK inhibitors by regulating p53-target selectivity in ALK-driven neuroblastomas. Cell Death Discov. 2018;4:56 pubmed 出版商
PEREZ ORTIZ J, Mollema N, Toker N, Adamski C, O Callaghan B, Duvick L, et al. Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model. Neurobiol Dis. 2018;116:93-105 pubmed 出版商
Iuso A, Wiersma M, Schüller H, Pode Shakked B, Marek Yagel D, Grigat M, et al. Mutations in PPCS, Encoding Phosphopantothenoylcysteine Synthetase, Cause Autosomal-Recessive Dilated Cardiomyopathy. Am J Hum Genet. 2018;102:1018-1030 pubmed 出版商
Shrestha D, Choi D, Song K. Actin Dysfunction Induces Cell Cycle Delay at G2/M with Sustained ERK and RSK Activation in IMR-90 Normal Human Fibroblasts. Mol Cells. 2018;41:436-443 pubmed 出版商
Kota S, Hou S, Guerrant W, Madoux F, Troutman S, Fernandez Vega V, et al. A novel three-dimensional high-throughput screening approach identifies inducers of a mutant KRAS selective lethal phenotype. Oncogene. 2018;37:4372-4384 pubmed 出版商
Copeland S, McRae A, Guarguaglini G, Trinkle Mulcahy L, Copeland J. Actin-dependent regulation of cilia length by the inverted formin FHDC1. Mol Biol Cell. 2018;29:1611-1627 pubmed 出版商
Duan T, Geyer P. Spermiogenesis and Male Fertility Require the Function of Suppressor of Hairy-Wing in Somatic Cyst Cells of Drosophila. Genetics. 2018;209:757-772 pubmed 出版商
Clarisse D, Van Wesemael K, Tavernier J, Offner F, Beck I, De Bosscher K. Effect of combining glucocorticoids with Compound A on glucocorticoid receptor responsiveness in lymphoid malignancies. PLoS ONE. 2018;13:e0197000 pubmed 出版商
Kogenaru M, Isalan M. Drug-Inducible Control of Lethality Genes: A Low Background Destabilizing Domain Architecture Applied to the Gal4-UAS System in Drosophila. ACS Synth Biol. 2018;7:1496-1506 pubmed 出版商
Wang Y, Zhang W, Yu G, Liu Q, Jin Y. Cytoprotective effect of aquaporin 1 against lipopolysaccharide-induced apoptosis and inflammation of renal epithelial HK-2 cells. Exp Ther Med. 2018;15:4243-4252 pubmed 出版商
Schmidt A, Marabita F, Kiani N, Gross C, Johansson H, Elias S, et al. Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3. BMC Biol. 2018;16:47 pubmed 出版商
Liss K, McCommis K, Chambers K, Pietka T, Schweitzer G, Park S, et al. The impact of diet-induced hepatic steatosis in a murine model of hepatic ischemia/reperfusion injury. Liver Transpl. 2018;24:908-921 pubmed 出版商
Hossain D, Ferreira Barbosa J, Cohen E, Tsang W. HIV-1 Vpr hijacks EDD-DYRK2-DDB1DCAF1 to disrupt centrosome homeostasis. J Biol Chem. 2018;293:9448-9460 pubmed 出版商
Hsieh Y, Tung S, Pan H, Yen C, Xu H, Deng Y, et al. Upregulation of bone morphogenetic protein 1 is associated with poor prognosis of late-stage gastric Cancer patients. BMC Cancer. 2018;18:508 pubmed 出版商
Bütepage M, Preisinger C, von Kriegsheim A, Scheufen A, Lausberg E, Li J, et al. Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription. Sci Rep. 2018;8:6748 pubmed 出版商
Zhu Z, Chen D, Zhang W, Zhao J, Zhi L, Huang F, et al. Modulation of alternative splicing induced by paclitaxel in human lung cancer. Cell Death Dis. 2018;9:491 pubmed 出版商
Drpic D, Almeida A, Aguiar P, Renda F, Damas J, Lewin H, et al. Chromosome Segregation Is Biased by Kinetochore Size. Curr Biol. 2018;28:1344-1356.e5 pubmed 出版商
Ristić G, Sutton J, Libohova K, Todi S. Toxicity and aggregation of the polyglutamine disease protein, ataxin-3 is regulated by its binding to VCP/p97 in Drosophila melanogaster. Neurobiol Dis. 2018;116:78-92 pubmed 出版商
Kato M, Takemoto K, Shinkai Y. A somatic role for the histone methyltransferase Setdb1 in endogenous retrovirus silencing. Nat Commun. 2018;9:1683 pubmed 出版商
Feng J, Wickenhagen A, Turnbull M, Rezelj V, Kreher F, Tilston Lunel N, et al. Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20. J Virol. 2018;92: pubmed 出版商
Norrmen C, Figlia G, Pfistner P, Pereira J, Bachofner S, Suter U. mTORC1 Is Transiently Reactivated in Injured Nerves to Promote c-Jun Elevation and Schwann Cell Dedifferentiation. J Neurosci. 2018;38:4811-4828 pubmed 出版商
Hsu C, Lecland N, Pendaries V, Viodé C, Redoules D, Paul C, et al. Stabilization of microtubules restores barrier function after cytokine-induced defects in reconstructed human epidermis. J Dermatol Sci. 2018;91:87-96 pubmed 出版商
Kristen H, Sastre I, Muñoz Galdeano T, Recuero M, Aldudo J, Bullido M. The lysosome system is severely impaired in a cellular model of neurodegeneration induced by HSV-1 and oxidative stress. Neurobiol Aging. 2018;68:5-17 pubmed 出版商
Jones B, Buenaventura T, Kanda N, Chabosseau P, Owen B, Scott R, et al. Targeting GLP-1 receptor trafficking to improve agonist efficacy. Nat Commun. 2018;9:1602 pubmed 出版商
Mercado Matos J, Janusis J, Zhu S, Chen S, Shaw L. Identification of a Novel Invasion-Promoting Region in Insulin Receptor Substrate 2. Mol Cell Biol. 2018;38: pubmed 出版商
Dyshlovoy S, Otte K, Tabakmakher K, Hauschild J, Makarieva T, Shubina L, et al. Synthesis and anticancer activity of the derivatives of marine compound rhizochalin in castration resistant prostate cancer. Oncotarget. 2018;9:16962-16973 pubmed 出版商
Griveau A, Seano G, Shelton S, Kupp R, Jahangiri A, Obernier K, et al. A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment. Cancer Cell. 2018;33:874-889.e7 pubmed 出版商
Lancaster G, Langley K, Berglund N, Kammoun H, Reibe S, Estevez E, et al. Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism. Cell Metab. 2018;27:1096-1110.e5 pubmed 出版商
Vodicska B, Cerikan B, Schiebel E, Hoffmann I. MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression. Sci Rep. 2018;8:6330 pubmed 出版商
Hortua Triana M, Márquez Nogueras K, Chang L, Stasic A, Li C, Spiegel K, et al. Tagging of Weakly Expressed Toxoplasma gondii Calcium-Related Genes with High-Affinity Tags. J Eukaryot Microbiol. 2018;65:709-721 pubmed 出版商
Rodríguez Muela N, Parkhitko A, Grass T, Gibbs R, Norabuena E, Perrimon N, et al. Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes. J Clin Invest. 2018;128:3008-3023 pubmed 出版商
Dang Nguyen T, Nguyen H, Somfai T, Wells D, Men N, Viet Linh N, et al. Sucrose assists selection of high-quality oocytes in pigs. Anim Sci J. 2018;89:880-887 pubmed 出版商
Zhu S, Ward B, Yu J, Matthew Onabanjo A, Janusis J, Hsieh C, et al. IRS2 mutations linked to invasion in pleomorphic invasive lobular carcinoma. JCI Insight. 2018;3: pubmed 出版商
Liu H, Dai X, Cao X, Yan H, Ji X, Zhang H, et al. PRDM4 mediates YAP-induced cell invasion by activating leukocyte-specific integrin β2 expression. EMBO Rep. 2018;19: pubmed 出版商
Kschonsak Y, Hoffmann I. Activated ezrin controls MISP levels to ensure correct NuMA polarization and spindle orientation. J Cell Sci. 2018;131: pubmed 出版商
Frye M, Taddei A, Dierkes C, Martínez Corral I, Fielden M, Ortsäter H, et al. Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program. Nat Commun. 2018;9:1511 pubmed 出版商
Jiang W, Wei Y, Long Y, Owen A, Wang B, Wu X, et al. A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans. elife. 2018;7: pubmed 出版商
Huang S, Liu Y, Chen Y, Yeh Y, Huang H. CD69 partially inhibits apoptosis and erythroid differentiation via CD24, and their knockdown increase imatinib sensitivity in BCR-ABL-positive cells. J Cell Physiol. 2018;233:7467-7479 pubmed 出版商
Corallino S, Malinverno C, Neumann B, Tischer C, Palamidessi A, Frittoli E, et al. A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration. Nat Commun. 2018;9:1475 pubmed 出版商
Zolezzi J, Lindsay C, Serrano F, Ureta R, Theoduloz C, Schmeda Hirschmann G, et al. Neuroprotective Effects of Ferruginol, Jatrophone, and Junicedric Acid Against Amyloid-β Injury in Hippocampal Neurons. J Alzheimers Dis. 2018;63:705-723 pubmed 出版商
Chan X, Balasundaram G, Attia A, Goggi J, Ramasamy B, Han W, et al. Multimodal imaging approach to monitor browning of adipose tissue in vivo. J Lipid Res. 2018;59:1071-1078 pubmed 出版商
Montgomery K, Louis Sam Titus A, Wang L, D Mello S. Elevated MeCP2 in Mice Causes Neurodegeneration Involving Tau Dysregulation and Excitotoxicity: Implications for the Understanding and Treatment of MeCP2 Triplication Syndrome. Mol Neurobiol. 2018;55:9057-9074 pubmed 出版商
Porter L, Franczyk M, Pietka T, Yamaguchi S, Lin J, Sasaki Y, et al. NAD+-dependent deacetylase SIRT3 in adipocytes is dispensable for maintaining normal adipose tissue mitochondrial function and whole body metabolism. Am J Physiol Endocrinol Metab. 2018;315:E520-E530 pubmed 出版商
Kivinen N. The role of autophagy in age-related macular degeneration. Acta Ophthalmol. 2018;96 Suppl A110:1-50 pubmed 出版商
Eno C, Gomez T, Slusarski D, Pelegri F. Slow calcium waves mediate furrow microtubule reorganization and germ plasm compaction in the early zebrafish embryo. Development. 2018;145: pubmed 出版商
Cimino P, Kim Y, Wu H, Alexander J, Wirsching H, Szulzewsky F, et al. Increased HOXA5 expression provides a selective advantage for gain of whole chromosome 7 in IDH wild-type glioblastoma. Genes Dev. 2018;32:512-523 pubmed 出版商
Xiong J, Almeida M, O Brien C. The YAP/TAZ transcriptional co-activators have opposing effects at different stages of osteoblast differentiation. Bone. 2018;112:1-9 pubmed 出版商
Furlan T, Khalid S, Nguyen A, Günther J, Troppmair J. The oxidoreductase p66Shc acts as tumor suppressor in BRAFV600E-transformed cells. Mol Oncol. 2018;12:869-882 pubmed 出版商
Egusquiaguirre S, Yeh J, Walker S, Liu S, Frank D. The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway in Breast Cancer Cells. Neoplasia. 2018;20:489-498 pubmed 出版商
Liu Y, Chang Y, Chen L, Su P, Ko W, Tsai Y, et al. The ATP-P2X7 Signaling Axis Is an Essential Sentinel for Intracellular Clostridium difficile Pathogen-Induced Inflammasome Activation. Front Cell Infect Microbiol. 2018;8:84 pubmed 出版商
Morales Alamo D, Guerra B, Santana A, Martin Rincon M, Gelabert Rebato M, Dorado C, et al. Skeletal Muscle Pyruvate Dehydrogenase Phosphorylation and Lactate Accumulation During Sprint Exercise in Normoxia and Severe Acute Hypoxia: Effects of Antioxidants. Front Physiol. 2018;9:188 pubmed 出版商
Zhang Y, Ulvmar M, Stanczuk L, Martínez Corral I, Frye M, Alitalo K, et al. Heterogeneity in VEGFR3 levels drives lymphatic vessel hyperplasia through cell-autonomous and non-cell-autonomous mechanisms. Nat Commun. 2018;9:1296 pubmed 出版商
Tang H, Hu Y, Chen C, Xia B, ZIRIN J, Yuan M, et al. The TORC1-Regulated CPA Complex Rewires an RNA Processing Network to Drive Autophagy and Metabolic Reprogramming. Cell Metab. 2018;27:1040-1054.e8 pubmed 出版商
Wharton T, Nomie K, Wharton R. No significant regulation of bicoid mRNA by Pumilio or Nanos in the early Drosophila embryo. PLoS ONE. 2018;13:e0194865 pubmed 出版商
Hülsmann J, Kravic B, Weith M, Gstaiger M, Aebersold R, Collins B, et al. AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation. Mol Cell Proteomics. 2018;17:1295-1307 pubmed 出版商
Romero M, Sabaté Pérez A, Francis V, Castrillón Rodriguez I, Diaz Ramos A, Sánchez Feutrie M, et al. TP53INP2 regulates adiposity by activating β-catenin through autophagy-dependent sequestration of GSK3β. Nat Cell Biol. 2018;20:443-454 pubmed 出版商
Dema A, Macaluso F, Sgrò F, Berto G, Bianchi F, Chiotto A, et al. Citron kinase-dependent F-actin maintenance at midbody secondary ingression sites mediates abscission. J Cell Sci. 2018;131: pubmed 出版商
Kim M, Jeon S, Burbulla L, Krainc D. Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function. Hum Mol Genet. 2018;27:1972-1988 pubmed 出版商
Fan Q, Moen A, Anonsen J, Bindesbøll C, Sæther T, Carlson C, et al. O-GlcNAc site-mapping of liver X receptor-α and O-GlcNAc transferase. Biochem Biophys Res Commun. 2018;499:354-360 pubmed 出版商
Sivakrishna B, Islam S, Panda A, Saranya M, Santra M, Pal S. Synthesis and Anticancer Properties of Novel Truncated Carbocyclic Nucleoside Analogues. Anticancer Agents Med Chem. 2018;18:1425-1431 pubmed 出版商
Namkoong S, Ho A, Woo Y, Kwak H, Lee J. Systematic Characterization of Stress-Induced RNA Granulation. Mol Cell. 2018;70:175-187.e8 pubmed 出版商
Kim R, Kim J, Chung C, Ha S, Lee S, Lee E, et al. Cell-Type-Specific Shank2 Deletion in Mice Leads to Differential Synaptic and Behavioral Phenotypes. J Neurosci. 2018;38:4076-4092 pubmed 出版商
Díaz Viraqué F, Chiribao M, Trochine A, González Herrera F, Castillo C, Liempi A, et al. Old Yellow Enzyme from Trypanosoma cruzi Exhibits In Vivo Prostaglandin F2α Synthase Activity and Has a Key Role in Parasite Infection and Drug Susceptibility. Front Immunol. 2018;9:456 pubmed 出版商
Mendes M, Bonfleur M, Ribeiro R, Lubaczeuski C, Fêo A, Vargas R, et al. Duodeno-jejunal bypass restores β-cell hypersecretion and islet hypertrophy in western diet obese rats. Endocrine. 2018;60:407-414 pubmed 出版商
Courtheoux T, Diallo A, Damodaran A, Reboutier D, Watrin E, Prigent C. Aurora A kinase activity is required to maintain an active spindle assembly checkpoint during prometaphase. J Cell Sci. 2018;131: pubmed 出版商
Modi S, Yaluri N, Kokkola T. Strigolactone GR24 and pinosylvin attenuate adipogenesis and inflammation of white adipocytes. Biochem Biophys Res Commun. 2018;499:164-169 pubmed 出版商
Dubeaux G, Neveu J, Zelazny E, Vert G. Metal Sensing by the IRT1 Transporter-Receptor Orchestrates Its Own Degradation and Plant Metal Nutrition. Mol Cell. 2018;69:953-964.e5 pubmed 出版商
Martin M, Veloso A, Wu J, Katrukha E, Akhmanova A. Control of endothelial cell polarity and sprouting angiogenesis by non-centrosomal microtubules. elife. 2018;7: pubmed 出版商
Ben Djoudi Ouadda A, He Y, Calabrese V, Ishii H, Chidiac R, Gratton J, et al. CdGAP/ARHGAP31 is regulated by RSK phosphorylation and binding to 14-3-3β adaptor protein. Oncotarget. 2018;9:11646-11664 pubmed 出版商
Richter K, Paakkola T, Mennerich D, Kubaichuk K, Konzack A, Ali Kippari H, et al. USP28 Deficiency Promotes Breast and Liver Carcinogenesis as well as Tumor Angiogenesis in a HIF-independent Manner. Mol Cancer Res. 2018;16:1000-1012 pubmed 出版商
Daubriac J, Han S, Grahovac J, Smith E, Hosein A, Buchanan M, et al. The crosstalk between breast carcinoma-associated fibroblasts and cancer cells promotes RhoA-dependent invasion via IGF-1 and PAI-1. Oncotarget. 2018;9:10375-10387 pubmed 出版商
Schippers K, Nichols S. Evidence of Signaling and Adhesion Roles for ?-Catenin in the Sponge Ephydatia muelleri. Mol Biol Evol. 2018;35:1407-1421 pubmed 出版商
Guida N, Valsecchi V, Laudati G, Serani A, Mascolo L, Molinaro P, et al. The miR206-JunD Circuit Mediates the Neurotoxic Effect of Methylmercury in Cortical Neurons. Toxicol Sci. 2018;163:569-578 pubmed 出版商
Zhou L, Xiong J, Ruan C, Ruan Y, Liu D, Bao J, et al. ProBDNF/p75NTR/sortilin pathway is activated in peripheral blood of patients with alcohol dependence. Transl Psychiatry. 2018;7:2 pubmed 出版商
Teng Y, Wang Y, Hsu P, Xin G, Zhang Y, Morris Natschke S, et al. Mechanism of action of cytotoxic compounds from the seeds of Euphorbia lathyris. Phytomedicine. 2018;41:62-66 pubmed 出版商
Pietrovito L, Leo A, Gori V, Lulli M, Parri M, Becherucci V, et al. Bone marrow-derived mesenchymal stem cells promote invasiveness and transendothelial migration of osteosarcoma cells via a mesenchymal to amoeboid transition. Mol Oncol. 2018;12:659-676 pubmed 出版商
Rahnasto Rilla M, Tyni J, Huovinen M, Jarho E, Kulikowicz T, Ravichandran S, et al. Natural polyphenols as sirtuin 6 modulators. Sci Rep. 2018;8:4163 pubmed 出版商
Bozatzi P, Dingwell K, Wu K, Cooper F, Cummins T, Hutchinson L, et al. PAWS1 controls Wnt signalling through association with casein kinase 1α. EMBO Rep. 2018;19: pubmed 出版商
Kataoka K, Maehara N, Ayabe Y, Murata H, Huh N, Sakaguchi M. Tumor necrosis factor-α downregulates the REIC/Dkk-3 tumor suppressor gene in normal human skin keratinocytes. Mol Med Rep. 2018;17:6661-6666 pubmed 出版商
Li X, Ruan X, Zhang P, Yu Y, Gao M, Yuan S, et al. TBX3 promotes proliferation of papillary thyroid carcinoma cells through facilitating PRC2-mediated p57KIP2 repression. Oncogene. 2018;37:2773-2792 pubmed 出版商
Girnius N, Edwards Y, Davis R. The cJUN NH2-terminal kinase (JNK) pathway contributes to mouse mammary gland remodeling during involution. Cell Death Differ. 2018;25:1702-1715 pubmed 出版商
Sin Y, Ballantyne L, Richmond C, Funk C. Transplantation of Gene-Edited Hepatocyte-like Cells Modestly Improves Survival of Arginase-1-Deficient Mice. Mol Ther Nucleic Acids. 2018;10:122-130 pubmed 出版商
Lin C, Shih C, Lin Y, Yang Y, Chen B. MEKK1, JNK, and SMAD3 mediate CXCL12-stimulated connective tissue growth factor expression in human lung fibroblasts. J Biomed Sci. 2018;25:19 pubmed 出版商
Baranes Bachar K, Levy Barda A, Oehler J, Reid D, Soria Bretones I, Voss T, et al. The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair. Mol Cell. 2018;69:866-878.e7 pubmed 出版商
Bai M, Vozdek R, Hnizda A, Jiang C, Wang B, Kuchar L, et al. Conserved roles of C. elegans and human MANFs in sulfatide binding and cytoprotection. Nat Commun. 2018;9:897 pubmed 出版商
de Castro I, Gil R, Ligammari L, Di Giacinto M, Vagnarelli P. CDK1 and PLK1 coordinate the disassembly and reassembly of the nuclear envelope in vertebrate mitosis. Oncotarget. 2018;9:7763-7773 pubmed 出版商
Puglisi R, Bellenghi M, Pontecorvi G, Gulino A, Petrini M, Felicetti F, et al. SCD5 restored expression favors differentiation and epithelial-mesenchymal reversion in advanced melanoma. Oncotarget. 2018;9:7567-7581 pubmed 出版商
Gentsch G, Spruce T, Monteiro R, Owens N, Martin S, Smith J. Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus. Dev Cell. 2018;44:597-610.e10 pubmed 出版商
Elliott B, Zackery D, Eaton V, Jones R, Abebe F, RAGIN C, et al. Ethnic differences in TGFβ-signaling pathway may contribute to prostate cancer health disparity. Carcinogenesis. 2018;39:546-555 pubmed 出版商
Abdulrahman N, Jaspard Vinassa B, Fliegel L, Jabeen A, Riaz S, Gadeau A, et al. Na+/H+ exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase. Physiol Genomics. 2018;50:332-342 pubmed 出版商
Rizzi C, Tiberi A, Giustizieri M, Marrone M, Gobbo F, Carucci N, et al. NGF steers microglia toward a neuroprotective phenotype. Glia. 2018;66:1395-1416 pubmed 出版商
Yu Y, Xiong Y, Montani J, Yang Z, Ming X. Arginase-II activates mTORC1 through myosin-1b in vascular cell senescence and apoptosis. Cell Death Dis. 2018;9:313 pubmed 出版商
Göder A, Emmerich C, Nikolova T, Kiweler N, Schreiber M, Kühl T, et al. HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130. Nat Commun. 2018;9:764 pubmed 出版商
Contreras O, Villarreal M, Brandan E. Nilotinib impairs skeletal myogenesis by increasing myoblast proliferation. Skelet Muscle. 2018;8:5 pubmed 出版商
Sun X, Shi B, Zheng H, Min L, Yang J, Li X, et al. Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway. Cell Death Dis. 2018;9:260 pubmed 出版商
Su S, Flashner Abramson E, Klein S, Gal M, Lee R, Wu J, et al. Impact of the Anticancer Drug NT157 on Tyrosine Kinase Signaling Networks. Mol Cancer Ther. 2018;17:931-942 pubmed 出版商
Yu Y, Schleich K, Yue B, Ji S, Lohneis P, Kemper K, et al. Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma. Cancer Cell. 2018;33:322-336.e8 pubmed 出版商
Kutz L, Mukherji S, Wang X, Bryant A, Larre I, Heiny J, et al. Isoform-specific role of Na/K-ATPase α1 in skeletal muscle. Am J Physiol Endocrinol Metab. 2018;314:E620-E629 pubmed 出版商
Yamaguchi T, Suzuki T, Sato T, Takahashi A, Watanabe H, Kadowaki A, et al. The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function. Sci Signal. 2018;11: pubmed 出版商
Ufartes R, Schwenty Lara J, Freese L, Neuhofer C, Möller J, Wehner P, et al. Sema3a plays a role in the pathogenesis of CHARGE syndrome. Hum Mol Genet. 2018;27:1343-1352 pubmed 出版商
Nukina K, Hayashi A, Shiomi Y, Sugasawa K, Ohtsubo M, Nishitani H. Mutations at multiple CDK phosphorylation consensus sites on Cdt2 increase the affinity of CRL4Cdt2 for PCNA and its ubiquitination activity in S phase. Genes Cells. 2018;23:200-213 pubmed 出版商
Páez Moscoso D, Pan L, Sigauke R, Schroeder M, Tang W, Baumann P. Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast. Nat Commun. 2018;9:587 pubmed 出版商
Hor C, Goh E. Rab23 Regulates Radial Migration of Projection Neurons via N-cadherin. Cereb Cortex. 2018;28:1516-1531 pubmed 出版商
Mahoney S, Narayan S, Molz L, Berstler L, Kang S, Vlasuk G, et al. A small molecule inhibitor of Rheb selectively targets mTORC1 signaling. Nat Commun. 2018;9:548 pubmed 出版商
Galmarini C, Martin M, Bouchet B, Guillén Navarro M, Martínez Diez M, Martinez Leal J, et al. Plocabulin, a novel tubulin-binding agent, inhibits angiogenesis by modulation of microtubule dynamics in endothelial cells. BMC Cancer. 2018;18:164 pubmed 出版商
Hines T, Gao X, Sahu S, Lange M, Turner J, Twiss J, et al. An Essential Postdevelopmental Role for Lis1 in Mice. Eneuro. 2018;5: pubmed 出版商
Fauquenoy S, Migeot V, Finet O, Yague Sanz C, Khorosjutina O, Ekwall K, et al. Repression of Cell Differentiation by a cis-Acting lincRNA in Fission Yeast. Curr Biol. 2018;28:383-391.e3 pubmed 出版商
Okamoto Y, Iwasaki W, Kugou K, Takahashi K, Oda A, Sato K, et al. Replication stress induces accumulation of FANCD2 at central region of large fragile genes. Nucleic Acids Res. 2018;46:2932-2944 pubmed 出版商
Arrant A, Onyilo V, Unger D, Roberson E. Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis. J Neurosci. 2018;38:2341-2358 pubmed 出版商
Kizhakkedath P, John A, Al Gazali L, Ali B. Degradation routes of trafficking-defective VLDLR mutants associated with Dysequilibrium syndrome. Sci Rep. 2018;8:1583 pubmed 出版商
Kathayat R, Cao Y, Elvira P, Sandoz P, Zaballa M, Springer M, et al. Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes. Nat Commun. 2018;9:334 pubmed 出版商
Lv Z, Rosenbaum J, Aspelmeier T, Großhans J. A 'molecular guillotine' reveals the interphase function of Kinesin-5. J Cell Sci. 2018;131: pubmed 出版商
Uchino Y, Woodward A, Mauris J, Peterson K, Verma P, Nilsson U, et al. Galectin-3 is an amplifier of the interleukin-1β-mediated inflammatory response in corneal keratinocytes. Immunology. 2018;154:490-499 pubmed 出版商
Minns A, Hart K, Subramanian S, Hafenstein S, Lindner S. Nuclear, Cytosolic, and Surface-Localized Poly(A)-Binding Proteins of Plasmodium yoelii. mSphere. 2018;3: pubmed 出版商
Fiori M, Villanova L, Barbini C, De Angelis M, De Maria R. miR-663 sustains NSCLC by inhibiting mitochondrial outer membrane permeabilization (MOMP) through PUMA/BBC3 and BTG2. Cell Death Dis. 2018;9:49 pubmed 出版商
Wan L, Xu K, Wei Y, Zhang J, Han T, Fry C, et al. Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function. Mol Cell. 2018;69:279-291.e5 pubmed 出版商
Riquelme Guzman C, Contreras O, Brandan E. Expression of CTGF/CCN2 in response to LPA is stimulated by fibrotic extracellular matrix via the integrin/FAK axis. Am J Physiol Cell Physiol. 2018;314:C415-C427 pubmed 出版商
Beacham G, Partlow E, Lange J, Hollopeter G. NECAPs are negative regulators of the AP2 clathrin adaptor complex. elife. 2018;7: pubmed 出版商
Poirel O, Mella S, Videau C, Ramet L, Davoli M, Herzog E, et al. Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer's disease at various cognitive stages. Sci Rep. 2018;8:938 pubmed 出版商
Frattini V, Pagnotta S, Tala -, Fan J, Russo M, Lee S, et al. A metabolic function of FGFR3-TACC3 gene fusions in cancer. Nature. 2018;553:222-227 pubmed 出版商
Tani H, Ohnishi S, Shitara H, Mito T, Yamaguchi M, Yonekawa H, et al. Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal. Sci Rep. 2018;8:425 pubmed 出版商
Festa B, Chen Z, Berquez M, Debaix H, Tokonami N, Prange J, et al. Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney. Nat Commun. 2018;9:161 pubmed 出版商
Coll O, Guitart T, Villalba A, Papin C, Simonelig M, Gebauer F. Dicer-2 promotes mRNA activation through cytoplasmic polyadenylation. RNA. 2018;: pubmed 出版商
Lai S, Huang B, Liu Y, Lin H, Chen C, Tsai C, et al. Differential Characterization of Temozolomide-Resistant Human Glioma Cells. Int J Mol Sci. 2018;19: pubmed 出版商
Snyder A, Danthi P. Cleavage of the C-Terminal Fragment of Reovirus μ1 Is Required for Optimal Infectivity. J Virol. 2018;92: pubmed 出版商
Miret Casals L, Sebastian D, Brea J, Rico Leo E, Palacin M, Fernandez Salguero P, et al. Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism. Cell Chem Biol. 2018;25:268-278.e4 pubmed 出版商
Buenaventura T, Kanda N, Douzenis P, Jones B, Bloom S, Chabosseau P, et al. A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells. Diabetes. 2018;67:385-399 pubmed 出版商
Schlütermann D, Skowron M, Berleth N, Böhler P, Deitersen J, Stuhldreier F, et al. Targeting urothelial carcinoma cells by combining cisplatin with a specific inhibitor of the autophagy-inducing class III PtdIns3K complex. Urol Oncol. 2018;36:160.e1-160.e13 pubmed 出版商
Milanovic M, Fan D, Belenki D, Däbritz J, Zhao Z, Yu Y, et al. Senescence-associated reprogramming promotes cancer stemness. Nature. 2018;553:96-100 pubmed 出版商
Ingallina E, Sorrentino G, Bertolio R, Lisek K, Zannini A, Azzolin L, et al. Mechanical cues control mutant p53 stability through a mevalonate-RhoA axis. Nat Cell Biol. 2018;20:28-35 pubmed 出版商
Schmid F, Schou K, Vilhelm M, Holm M, Breslin L, Farinelli P, et al. IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases. J Cell Biol. 2018;217:151-161 pubmed 出版商
Bernard K, Logsdon N, Benavides G, SANDERS Y, Zhang J, Darley Usmar V, et al. Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation. J Biol Chem. 2018;293:1218-1228 pubmed 出版商
Krania P, Dimou E, Bantouna M, Kouvaros S, Tsiamaki E, Papatheodoropoulos C, et al. Adenosine A2A receptors are required for glutamate mGluR5- and dopamine D1 receptor-evoked ERK1/2 phosphorylation in rat hippocampus: involvement of NMDA receptor. J Neurochem. 2018;145:217-231 pubmed 出版商
Drebert Z, De Vlieghere E, Bridelance J, De Wever O, De Bosscher K, Bracke M, et al. Glucocorticoids indirectly decrease colon cancer cell proliferation and invasion via effects on cancer-associated fibroblasts. Exp Cell Res. 2018;362:332-342 pubmed 出版商
Burr S, Caldwell A, Chong M, Beretta M, Metcalf S, Hancock M, et al. Oxygen gradients can determine epigenetic asymmetry and cellular differentiation via differential regulation of Tet activity in embryonic stem cells. Nucleic Acids Res. 2018;46:1210-1226 pubmed 出版商
Urbanska M, Gozdz A, Macias M, Cymerman I, Liszewska E, Kondratiuk I, et al. GSK3β Controls mTOR and Prosurvival Signaling in Neurons. Mol Neurobiol. 2018;55:6050-6062 pubmed 出版商
Mygind K, Schwarz J, Sahgal P, Ivaska J, Kveiborg M. Loss of ADAM9 expression impairs β1 integrin endocytosis, focal adhesion formation and cancer cell migration. J Cell Sci. 2018;131: pubmed 出版商
Galoian K, Abrahamyan S, Chailyan G, Qureshi A, Patel P, Metser G, et al. Toll like receptors TLR1/2, TLR6 and MUC5B as binding interaction partners with cytostatic proline rich polypeptide 1 in human chondrosarcoma. Int J Oncol. 2018;52:139-154 pubmed 出版商
Ryan R, Failler M, Reilly M, Garfa Traoré M, Delous M, Filhol E, et al. Functional characterization of tektin-1 in motile cilia and evidence for TEKT1 as a new candidate gene for motile ciliopathies. Hum Mol Genet. 2018;27:266-282 pubmed 出版商
Cheng L, Tu K, Seidel C, Robb S, Guo F, SANCHEZ ALVARADO A. Cellular, ultrastructural and molecular analyses of epidermal cell development in the planarian Schmidtea mediterranea. Dev Biol. 2018;433:357-373 pubmed 出版商
Costa Besada M, Valenzuela R, Garrido Gil P, Villar Cheda B, Parga J, Lanciego J, et al. Paracrine and Intracrine Angiotensin 1-7/Mas Receptor Axis in the Substantia Nigra of Rodents, Monkeys, and Humans. Mol Neurobiol. 2018;55:5847-5867 pubmed 出版商
Martin C, Petersen K, Aoudjit L, Tilak M, Eremina V, Hardy W, et al. ShcA Adaptor Protein Promotes Nephrin Endocytosis and Is Upregulated in Proteinuric Nephropathies. J Am Soc Nephrol. 2018;29:92-103 pubmed 出版商
Lee I, Ho X, George S, Goh C, Sundaram J, Pang K, et al. Oxidative stress promotes SIRT1 recruitment to the GADD34/PP1α complex to activate its deacetylase function. Cell Death Differ. 2018;25:255-267 pubmed 出版商
Yamaguchi H, Du Y, Nakai K, Ding M, Chang S, Hsu J, et al. EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancer. Oncogene. 2018;37:208-217 pubmed 出版商
Wu C, Liu Z. Proteomic Profiling of Sweat Exosome Suggests its Involvement in Skin Immunity. J Invest Dermatol. 2018;138:89-97 pubmed 出版商
Shrestha D, Kim N, Song K. Stathmin/Op18 depletion induces genomic instability and leads to premature senescence in human normal fibroblasts. J Cell Biochem. 2018;119:2381-2395 pubmed 出版商
Sutherland J, Sobinoff A, Fraser B, Redgrove K, Siddall N, Koopman P, et al. RNA binding protein Musashi-2 regulates PIWIL1 and TBX1 in mouse spermatogenesis. J Cell Physiol. 2018;233:3262-3273 pubmed 出版商
Song G, Jeon H, Seo M, Jo M, Suk K. Interaction between optineurin and Rab1a regulates autophagosome formation in neuroblastoma cells. J Neurosci Res. 2018;96:407-415 pubmed 出版商
Kwon N, Lee M, Kong J, Park S, Hwang B, Kim B, et al. Transfer-RNA-mediated enhancement of ribosomal proteins S6 kinases signaling for cell proliferation. RNA Biol. 2018;15:635-648 pubmed 出版商
Sagredo A, Sagredo E, Cappelli C, Báez P, Andaur R, Blanco C, et al. TRPM4 regulates Akt/GSK3-? activity and enhances ?-catenin signaling and cell proliferation in prostate cancer cells. Mol Oncol. 2018;12:151-165 pubmed 出版商
Hay J, Jordan E, Browne G, Bottrill A, Prigent S, Dickens M. Transcriptional and Post-Translational Targeting of Myocyte Stress Protein 1 (MS1) by the JNK Pathway in Cardiac Myocytes. J Mol Signal. 2017;12:3 pubmed 出版商
Gatta L, Vitiello L, Gorini S, Chiandotto S, Costelli P, Giammarioli A, et al. Modulating the metabolism by trimetazidine enhances myoblast differentiation and promotes myogenesis in cachectic tumor-bearing c26 mice. Oncotarget. 2017;8:113938-113956 pubmed 出版商
Moloney J, Jayavelu A, Stanicka J, Roche S, O Brien R, Scholl S, et al. Nuclear membrane-localised NOX4D generates pro-survival ROS in FLT3-ITD-expressing AML. Oncotarget. 2017;8:105440-105457 pubmed 出版商
Sun Y, Zhang J, Chen S. Suppression of Alzheimer's disease-related phenotypes by the heat shock protein 70 inducer, geranylgeranylacetone, in APP/PS1 transgenic mice via the ERK/p38 MAPK signaling pathway. Exp Ther Med. 2017;14:5267-5274 pubmed 出版商
Subedi L, Kwon O, Pak C, Lee G, Lee K, Kim H, et al. N,N-disubstituted azines attenuate LPS-mediated neuroinflammation in microglia and neuronal apoptosis via inhibiting MAPK signaling pathways. BMC Neurosci. 2017;18:82 pubmed 出版商
Cao J, Ehling M, März S, Seebach J, Tarbashevich K, Sixta T, et al. Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis. Nat Commun. 2017;8:2210 pubmed 出版商
Lee J, Lee J, Chae B, Jang J, Lee E, Son Y. Fully Dedifferentiated Chondrocytes Expanded in Specific Mesenchymal Stem Cell Growth Medium with FGF2 Obtains Mesenchymal Stem Cell Phenotype In Vitro but Retains Chondrocyte Phenotype In Vivo. Cell Transplant. 2017;26:1673-1687 pubmed 出版商
Cerruti F, Jocollè G, Salio C, Oliva L, Paglietti L, Alessandria B, et al. Proteasome stress sensitizes malignant pleural mesothelioma cells to bortezomib-induced apoptosis. Sci Rep. 2017;7:17626 pubmed 出版商
Modi S, Yaluri N, Kokkola T, Laakso M. Plant-derived compounds strigolactone GR24 and pinosylvin activate SIRT1 and enhance glucose uptake in rat skeletal muscle cells. Sci Rep. 2017;7:17606 pubmed 出版商
Tapia Rojas C, Inestrosa N. Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20-APP transgenic and wild-type mice. J Neurochem. 2017;: pubmed 出版商
Hamada S, Taguchi K, Masamune A, Yamamoto M, Shimosegawa T. Nrf2 promotes mutant K-ras/p53-driven pancreatic carcinogenesis. Carcinogenesis. 2017;38:661-670 pubmed 出版商
Shin H, Haupt K, Kershner A, Kroll Conner P, Wickens M, Kimble J. SYGL-1 and LST-1 link niche signaling to PUF RNA repression for stem cell maintenance in Caenorhabditis elegans. PLoS Genet. 2017;13:e1007121 pubmed 出版商
Lu H, Shamanna R, de Freitas J, Okur M, Khadka P, Kulikowicz T, et al. Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair. Nat Commun. 2017;8:2039 pubmed 出版商
Espana Agusti J, Warren A, Chew S, Adams D, Matakidou A. Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis. Nat Commun. 2017;8:2026 pubmed 出版商
Shin H, Kim D, Helfman D. Tropomyosin isoform Tpm2.1 regulates collective and amoeboid cell migration and cell aggregation in breast epithelial cells. Oncotarget. 2017;8:95192-95205 pubmed 出版商
Haller S, Kapuria S, Riley R, O Leary M, Schreiber K, Andersen J, et al. mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance. Cell Stem Cell. 2017;21:806-818.e5 pubmed 出版商
Wutz G, Várnai C, Nagasaka K, Cisneros D, Stocsits R, Tang W, et al. Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins. EMBO J. 2017;36:3573-3599 pubmed 出版商
Shigeeda W, Shibazaki M, Yasuhira S, Masuda T, Tanita T, Kaneko Y, et al. Hyaluronic acid enhances cell migration and invasion via the YAP1/TAZ-RHAMM axis in malignant pleural mesothelioma. Oncotarget. 2017;8:93729-93740 pubmed 出版商
Woo S, Lee K, Lee G, Park J, Lee H, Bahn H, et al. Novel herbal medicine LA16001 ameliorates cisplatin-induced anorexia. Mol Med Rep. 2017;: pubmed 出版商
Moysés Oliveira M, Giannuzzi G, Fish R, Rosenfeld J, Petit F, de Fátima Soares M, et al. Inactivation of AMMECR1 is associated with growth, bone and heart alterations. Hum Mutat. 2017;: pubmed 出版商
Matilainen O, Sleiman M, Quirós P, Garcia S, Auwerx J. The chromatin remodeling factor ISW-1 integrates organismal responses against nuclear and mitochondrial stress. Nat Commun. 2017;8:1818 pubmed 出版商
Burguera D, Márquez Y, Racioppi C, Permanyer J, Torres Méndez A, Esposito R, et al. Evolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes. Nat Commun. 2017;8:1799 pubmed 出版商
Harrell J, Shroka T, Jacobsen B. Estrogen induces c-Kit and an aggressive phenotype in a model of invasive lobular breast cancer. Oncogenesis. 2017;6:396 pubmed 出版商
Kelsey I, Zbinden M, Byles V, Torrence M, Manning B. mTORC1 suppresses PIM3 expression via miR-33 encoded by the SREBP loci. Sci Rep. 2017;7:16112 pubmed 出版商
Wang Y, Zhao L, Hu Z, Wang Y, Zhao Z, Li L, et al. Quantitative performance evaluation of a back-illuminated sCMOS camera with 95% QE for super-resolution localization microscopy. Cytometry A. 2017;: pubmed 出版商
Allavena G, Cuomo F, Baumgartner G, Bele T, Sellgren A, Oo K, et al. Suppressed translation as a mechanism of initiation of CASP8 (caspase 8)-dependent apoptosis in autophagy-deficient NSCLC cells under nutrient limitation. Autophagy. 2017;:1-35 pubmed 出版商
Fusella F, Seclì L, Busso E, Krepelova A, Moiso E, Rocca S, et al. The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis. Nat Commun. 2017;8:1636 pubmed 出版商
Li P, Jiang W, Yu Q, Liu W, Zhou P, Li J, et al. Ubiquitination and degradation of GBPs by a Shigella effector to suppress host defence. Nature. 2017;551:378-383 pubmed 出版商
Braccioli L, Vervoort S, Adolfs Y, Heijnen C, Basak O, Pasterkamp R, et al. FOXP1 Promotes Embryonic Neural Stem Cell Differentiation by Repressing Jagged1 Expression. Stem Cell Reports. 2017;9:1530-1545 pubmed 出版商
Girnius N, Davis R. JNK Promotes Epithelial Cell Anoikis by Transcriptional and Post-translational Regulation of BH3-Only Proteins. Cell Rep. 2017;21:1910-1921 pubmed 出版商
Song D, Lee G, Nam S, Cheong J, Jeong D, Lee S, et al. TM4SF5 promotes metastatic behavior of cells in 3D extracellular matrix gels by reducing dependency on environmental cues. Oncotarget. 2017;8:83480-83494 pubmed 出版商
Dunleavy J, Okuda H, O Connor A, Merriner D, O Donnell L, Jamsai D, et al. Katanin-like 2 (KATNAL2) functions in multiple aspects of haploid male germ cell development in the mouse. PLoS Genet. 2017;13:e1007078 pubmed 出版商
Fei J, Jadaliha M, Harmon T, Li I, Hua B, Hao Q, et al. Quantitative analysis of multilayer organization of proteins and RNA in nuclear speckles at super resolution. J Cell Sci. 2017;130:4180-4192 pubmed 出版商
Molinari F, Pin F, Gorini S, Chiandotto S, Pontecorvo L, Penna F, et al. The mitochondrial metabolic reprogramming agent trimetazidine as an 'exercise mimetic' in cachectic C26-bearing mice. J Cachexia Sarcopenia Muscle. 2017;8:954-973 pubmed 出版商
Colecchia D, Stasi M, Leonardi M, Manganelli F, Nolano M, Veneziani B, et al. Alterations of autophagy in the peripheral neuropathy Charcot-Marie-Tooth type 2B. Autophagy. 2017;: pubmed 出版商
Chen Y, McCommis K, Ferguson D, Hall A, Harris C, Finck B. Inhibition of the Mitochondrial Pyruvate Carrier by Tolylfluanid. Endocrinology. 2017;: pubmed 出版商
Balhuizen A, Massa S, Mathijs I, Turatsinze J, De Vos J, Demine S, et al. A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells. Sci Rep. 2017;7:15130 pubmed 出版商
Helle S, Feng Q, Aebersold M, Hirt L, Grüter R, Vahid A, et al. Mechanical force induces mitochondrial fission. elife. 2017;6: pubmed 出版商
Yang J, Joshi S, Wang Q, Li P, Wang H, Xiong Y, et al. 14-3-3ζ loss leads to neonatal lethality by microRNA-126 downregulation-mediated developmental defects in lung vasculature. Cell Biosci. 2017;7:58 pubmed 出版商
Álvarez A, Uribe F, Canales J, Romero C, Soza A, Pena M, et al. KCTD5 and Ubiquitin Proteasome Signaling Are Required for Helicobacter pylori Adherence. Front Cell Infect Microbiol. 2017;7:450 pubmed 出版商
Zahreddine H, Culjkovic Kraljacic B, Emond A, Pettersson F, MIDURA R, Lauer M, et al. The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity. elife. 2017;6: pubmed 出版商
Tusco R, Jacomin A, Jain A, Penman B, Larsen K, Johansen T, et al. Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses. Nat Commun. 2017;8:1264 pubmed 出版商
Nakamuta S, Yang Y, Wang C, Gallo N, Yu J, Tai Y, et al. Dual role for DOCK7 in tangential migration of interneuron precursors in the postnatal forebrain. J Cell Biol. 2017;216:4313-4330 pubmed 出版商
Ivanov V, Wu J, Hei T. Regulation of human glioblastoma cell death by combined treatment of cannabidiol, ?-radiation and small molecule inhibitors of cell signaling pathways. Oncotarget. 2017;8:74068-74095 pubmed 出版商
Lewis C, Jin Z, Macdonald D, Wei W, Qian X, Choi W, et al. Prolonged mitotic arrest induced by Wee1 inhibition sensitizes breast cancer cells to paclitaxel. Oncotarget. 2017;8:73705-73722 pubmed 出版商
Rada P, Pardo V, Mobasher M, Garcia I, Ruiz L, Gonzalez Rodriguez A, et al. SIRT1 CONTROLS ACETAMINOPHEN HEPATOTOXICITY BY MODULATING INFLAMMATION AND OXIDATIVE STRESS. Antioxid Redox Signal. 2017;: pubmed 出版商
O Farrell F, Lobert V, Sneeggen M, Jain A, Katheder N, Wenzel E, et al. Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation. Nat Cell Biol. 2017;19:1412-1423 pubmed 出版商
Benke K, Mátyás C, Sayour A, Olah A, Németh B, Ruppert M, et al. Pharmacological preconditioning with gemfibrozil preserves cardiac function after heart transplantation. Sci Rep. 2017;7:14232 pubmed 出版商
Mizoguchi T, Ikeda S, Watanabe S, Sugawara M, Itoh M. Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway. Proc Natl Acad Sci U S A. 2017;114:E9280-E9289 pubmed 出版商
Yamada Y, Shimada T, Motomura Y, Sato F. Modulation of benzylisoquinoline alkaloid biosynthesis by heterologous expression of CjWRKY1 in Eschscholzia californica cells. PLoS ONE. 2017;12:e0186953 pubmed 出版商
Abate M, Laezza C, Pisanti S, Torelli G, Seneca V, Catapano G, et al. Deregulated expression and activity of Farnesyl Diphosphate Synthase (FDPS) in Glioblastoma. Sci Rep. 2017;7:14123 pubmed 出版商
Desgeorges M, Devillard X, Toutain J, Castells J, Divoux D, Arnould D, et al. Pharmacological inhibition of myostatin improves skeletal muscle mass and function in a mouse model of stroke. Sci Rep. 2017;7:14000 pubmed 出版商
Linder M, Köhler M, Boersema P, Weberruss M, Wandke C, Marino J, et al. Mitotic Disassembly of Nuclear Pore Complexes Involves CDK1- and PLK1-Mediated Phosphorylation of Key Interconnecting Nucleoporins. Dev Cell. 2017;43:141-156.e7 pubmed 出版商
Reza M, Subramaniyam N, Sim C, Ge X, Sathiakumar D, McFarlane C, et al. Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy. Nat Commun. 2017;8:1104 pubmed 出版商
Lehtimäki J, Fenix A, Kotila T, Balistreri G, Paavolainen L, Varjosalo M, et al. UNC-45a promotes myosin folding and stress fiber assembly. J Cell Biol. 2017;216:4053-4072 pubmed 出版商
Rothe C, Rødland G, Anda S, Stonyte V, Boye E, López Avilés S, et al. A checkpoint-independent mechanism delays entry into mitosis after UV irradiation. J Cell Sci. 2017;130:4028-4037 pubmed 出版商
Zhou W, Anderson A, Turner A, De Iuliis G, McCluskey A, McLaughlin E, et al. Characterization of a novel role for the dynamin mechanoenzymes in the regulation of human sperm acrosomal exocytosis. Mol Hum Reprod. 2017;23:657-673 pubmed 出版商
Tran D, Galletti R, Neumann E, Dubois A, Sharif Naeini R, Geitmann A, et al. A mechanosensitive Ca2+ channel activity is dependent on the developmental regulator DEK1. Nat Commun. 2017;8:1009 pubmed 出版商
Nadeem L, Shynlova O, Mesiano S, Lye S. Progesterone Via its Type-A Receptor Promotes Myometrial Gap Junction Coupling. Sci Rep. 2017;7:13357 pubmed 出版商
Jeon H, Park J, Shin J, Chang M. Insulin-like growth factor binding protein-6 released from human mesenchymal stem cells confers neuronal protection through IGF-1R-mediated signaling. Int J Mol Med. 2017;40:1860-1868 pubmed 出版商
Wang Z, Zhang F, He J, Wu P, Tay L, Cai M, et al. Binding of PLD2-Generated Phosphatidic Acid to KIF5B Promotes MT1-MMP Surface Trafficking and Lung Metastasis of Mouse Breast Cancer Cells. Dev Cell. 2017;43:186-197.e7 pubmed 出版商
Moriel Carretero M, Ovejero S, Gérus Durand M, Vryzas D, Constantinou A. Fanconi anemia FANCD2 and FANCI proteins regulate the nuclear dynamics of splicing factors. J Cell Biol. 2017;216:4007-4026 pubmed 出版商
Welch S, Scholte F, Flint M, Chatterjee P, Nichol S, Bergeron E, et al. Identification of 2'-deoxy-2'-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus. Antiviral Res. 2017;147:91-99 pubmed 出版商
Seoane M, Costoya J, Arce V. Uncoupling Oncogene-Induced Senescence (OIS) and DNA Damage Response (DDR) triggered by DNA hyper-replication: lessons from primary mouse embryo astrocytes (MEA). Sci Rep. 2017;7:12991 pubmed 出版商
Skrede S, González García I, Martins L, Berge R, Nogueiras R, Tena Sempere M, et al. Lack of ovarian secretions reverts the anabolic action of olanzapine in female rats. Int J Neuropsychopharmacol. 2017;: pubmed 出版商
Rüthemann P, Balbo Pogliano C, Codilupi T, Garajova Z, Naegeli H. Chromatin remodeler CHD1 promotes XPC-to-TFIIH handover of nucleosomal UV lesions in nucleotide excision repair. EMBO J. 2017;36:3372-3386 pubmed 出版商
Rajan A, Housden B, Wirtz Peitz F, Holderbaum L, Perrimon N. A Mechanism Coupling Systemic Energy Sensing to Adipokine Secretion. Dev Cell. 2017;43:83-98.e6 pubmed 出版商
Kirsch N, Chang L, Koch S, Glinka A, Dolde C, Colozza G, et al. Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. Dev Cell. 2017;43:71-82.e6 pubmed 出版商
Kawaguchi T, Machida S, Kurumizaka H, Tagami H, Nakayama J. Phosphorylation of CBX2 controls its nucleosome-binding specificity. J Biochem. 2017;162:343-355 pubmed 出版商
Zhang C, Liu X, He Q, Zheng H, Xu S, Xiong X, et al. miR?342?5p promotes Zmpste24?deficient mouse embryonic fibroblasts proliferation by suppressing GAS2. Mol Med Rep. 2017;16:8944-8952 pubmed 出版商
Zhang J, Jin Y, Pan J. Inhibitory effect of the anthelmintic drug pyrvinium pamoate on T315I BCR?ABL?positive CML cells. Mol Med Rep. 2017;16:9217-9223 pubmed 出版商
Yao L, Chen J, Wu X, Jia S, Meng A. Zebrafish cdc6 hypomorphic mutation causes Meier-Gorlin syndrome-like phenotype. Hum Mol Genet. 2017;26:4168-4180 pubmed 出版商
Haefliger J, Allagnat F, Hamard L, Le Gal L, Meda P, Nardelli Haefliger D, et al. Targeting Cx40 (Connexin40) Expression or Function Reduces Angiogenesis in the Developing Mouse Retina. Arterioscler Thromb Vasc Biol. 2017;37:2136-2146 pubmed 出版商
Jayaraman S, Chittiboyina S, Bai Y, Abad P, Vidi P, Stauffacher C, et al. The nuclear mitotic apparatus protein NuMA controls rDNA transcription and mediates the nucleolar stress response in a p53-independent manner. Nucleic Acids Res. 2017;45:11725-11742 pubmed 出版商
Yanagi T, Nagai K, Shimizu H, Matsuzawa S. Melanoma antigen A12 regulates cell cycle via tumor suppressor p21 expression. Oncotarget. 2017;8:68448-68459 pubmed 出版商
Leach J, Heallen T, Zhang M, Rahmani M, Morikawa Y, Hill M, et al. Hippo pathway deficiency reverses systolic heart failure after infarction. Nature. 2017;550:260-264 pubmed 出版商
Theil A, Mandemaker I, van den Akker E, Swagemakers S, Raams A, Wüst T, et al. Trichothiodystrophy causative TFIIE? mutation affects transcription in highly differentiated tissue. Hum Mol Genet. 2017;26:4689-4698 pubmed 出版商
Malone C, Emerson C, Ingraham R, Barbosa W, Guerra S, Yoon H, et al. mTOR and HDAC Inhibitors Converge on the TXNIP/Thioredoxin Pathway to Cause Catastrophic Oxidative Stress and Regression of RAS-Driven Tumors. Cancer Discov. 2017;7:1450-1463 pubmed 出版商
Zepeda Orozco D, Wen H, Hamilton B, Raikwar N, Thomas C. EGF regulation of proximal tubule cell proliferation and VEGF-A secretion. Physiol Rep. 2017;5: pubmed 出版商
Berndt N, Seib E, Kim S, Troost T, Lyga M, Langenbach J, et al. Ubiquitylation-independent activation of Notch signalling by Delta. elife. 2017;6: pubmed 出版商
Shi Y, Yamada K, Liddelow S, Smith S, Zhao L, Luo W, et al. ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy. Nature. 2017;549:523-527 pubmed 出版商
Hozumi S, Aoki S, Kikuchi Y. Nuclear movement regulated by non-Smad Nodal signaling via JNK is associated with Smad signaling during zebrafish endoderm specification. Development. 2017;144:4015-4025 pubmed 出版商
Solomon Zemler R, Sarfstein R, Werner H. Nuclear insulin-like growth factor-1 receptor (IGF1R) displays proliferative and regulatory activities in non-malignant cells. PLoS ONE. 2017;12:e0185164 pubmed 出版商
Méneret A, Franz E, Trouillard O, Oliver T, Zagar Y, Robertson S, et al. Mutations in the netrin-1 gene cause congenital mirror movements. J Clin Invest. 2017;127:3923-3936 pubmed 出版商
Song N, Liu Z, Xue W, Bai Z, Wang Q, Dai J, et al. NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation. Mol Cell. 2017;68:185-197.e6 pubmed 出版商
Lee C, Peng S, Shen L, Lee C, Du T, Kang M, et al. The Role of N-α-acetyltransferase 10 Protein in DNA Methylation and Genomic Imprinting. Mol Cell. 2017;68:89-103.e7 pubmed 出版商
Mai T, Hamai A, Hienzsch A, Cañeque T, Müller S, Wicinski J, et al. Salinomycin kills cancer stem cells by sequestering iron in lysosomes. Nat Chem. 2017;9:1025-1033 pubmed 出版商
Rashid M, Belmont J, Carpenter D, Turner C, Olson E. Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation. Development. 2017;144:4002-4014 pubmed 出版商
Borin D, Puzzi L, Martinelli V, Cibinel M, Lapasin R, Sbaizero O. An engineering insight into the relationship of selective cytoskeletal impairment and biomechanics of HeLa cells. Micron. 2017;102:88-96 pubmed 出版商
Daubriac J, Pandya U, Huang K, Pavlides S, Gama P, Blank S, et al. Hormonal and Growth Regulation of Epithelial and Stromal Cells From the Normal and Malignant Endometrium by Pigment Epithelium-Derived Factor. Endocrinology. 2017;158:2754-2773 pubmed 出版商
Ruan H, Ma Y, Torres S, Zhang B, Feriod C, Heck R, et al. Calcium-dependent O-GlcNAc signaling drives liver autophagy in adaptation to starvation. Genes Dev. 2017;31:1655-1665 pubmed 出版商
Pai C, Kishkevich A, Deegan R, Keszthelyi A, Folkes L, Kearsey S, et al. Set2 Methyltransferase Facilitates DNA Replication and Promotes Genotoxic Stress Responses through MBF-Dependent Transcription. Cell Rep. 2017;20:2693-2705 pubmed 出版商
Neu Yilik G, Raimondeau E, Eliseev B, Yeramala L, Amthor B, Deniaud A, et al. Dual function of UPF3B in early and late translation termination. EMBO J. 2017;36:2968-2986 pubmed 出版商
Barzago M, Kurosaki M, Fratelli M, Bolis M, Giudice C, Nordio L, et al. Generation of a new mouse model of glaucoma characterized by reduced expression of the AP-2β and AP-2δ proteins. Sci Rep. 2017;7:11140 pubmed 出版商
Cui Z, Tong A, Huo Y, Yan Z, Yang W, Yang X, et al. SKIP controls flowering time via the alternative splicing of SEF pre-mRNA in Arabidopsis. BMC Biol. 2017;15:80 pubmed 出版商
Weng T, Hung D, SU T, Tsai S. Loss of Sigma-1 Receptor Chaperone Promotes Astrocytosis and Enhances the Nrf2 Antioxidant Defense. Oxid Med Cell Longev. 2017;2017:4582135 pubmed 出版商
Stagni F, Giacomini A, Guidi S, Emili M, Uguagliati B, Salvalai M, et al. A flavonoid agonist of the TrkB receptor for BDNF improves hippocampal neurogenesis and hippocampus-dependent memory in the Ts65Dn mouse model of DS. Exp Neurol. 2017;298:79-96 pubmed 出版商
O Sullivan D, Dowling P, Joyce H, McAuley E, McCann A, Henry M, et al. A novel inhibitory anti-invasive MAb isolated using phenotypic screening highlights AnxA6 as a functionally relevant target protein in pancreatic cancer. Br J Cancer. 2017;117:1326-1335 pubmed 出版商
Villar Cheda B, Costa Besada M, Valenzuela R, Perez Costas E, Melendez Ferro M, Labandeira Garcia J. The intracellular angiotensin system buffers deleterious effects of the extracellular paracrine system. Cell Death Dis. 2017;8:e3044 pubmed 出版商
Figlia G, Norrmen C, Pereira J, Gerber D, Suter U. Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system. elife. 2017;6: pubmed 出版商
Feinberg K, Kolaj A, Wu C, Grinshtein N, Krieger J, Moran M, et al. A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria. J Cell Biol. 2017;216:3655-3675 pubmed 出版商
Theile D, Geng S, Denny E, Momand J, Kane S. t-Darpp stimulates protein kinase A activity by forming a complex with its RI regulatory subunit. Cell Signal. 2017;40:53-61 pubmed 出版商
Soares G, Cantelli K, Balbo S, Ribeiro R, Alegre Maller A, Barbosa Sampaio H, et al. Liver steatosis in hypothalamic obese rats improves after duodeno-jejunal bypass by reduction in de novo lipogenesis pathway. Life Sci. 2017;188:68-75 pubmed 出版商
Codenotti S, Vezzoli M, Poliani P, Cominelli M, Monti E, Fanzani A. Cavin-2 is a specific marker for detection of well-differentiated liposarcoma. Biochem Biophys Res Commun. 2017;493:660-665 pubmed 出版商
Joshi S, Yang J, Wang Q, Li P, Wang H, Zhang Q, et al. 14-3-3ζ loss impedes oncogene-induced mammary tumorigenesis and metastasis by attenuating oncogenic signaling. Am J Cancer Res. 2017;7:1654-1664 pubmed
Chiang T, Wu H, Lee F. ADP-ribosylation factor-like 4C binding to filamin-A modulates filopodium formation and cell migration. Mol Biol Cell. 2017;28:3013-3028 pubmed 出版商
Roccograndi L, Binder Z, Zhang L, Aceto N, Zhang Z, Bentires Alj M, et al. SHP2 regulates proliferation and tumorigenicity of glioma stem cells. J Neurooncol. 2017;135:487-496 pubmed 出版商
Kwun H, Wendzicki J, Shuda Y, Moore P, Chang Y. Merkel cell polyomavirus small T antigen induces genome instability by E3 ubiquitin ligase targeting. Oncogene. 2017;36:6784-6792 pubmed 出版商
Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, et al. Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nat Cell Biol. 2017;19:1116-1129 pubmed 出版商
Hildebrand S, Hultin S, Subramani A, Petropoulos S, Zhang Y, Cao X, et al. The E-cadherin/AmotL2 complex organizes actin filaments required for epithelial hexagonal packing and blastocyst hatching. Sci Rep. 2017;7:9540 pubmed 出版商
Gleixner A, Hutchison D, Sannino S, Bhatia T, Leak L, Flaherty P, et al. N-Acetyl-l-Cysteine Protects Astrocytes against Proteotoxicity without Recourse to Glutathione. Mol Pharmacol. 2017;92:564-575 pubmed 出版商
Gao C, Langbein L, Kamal F, George A, Walworth N. Kinetochore Components Required for Centromeric Chromatin Assembly Are Impacted by Msc1 in Schizosaccharomyces pombe. Genetics. 2017;207:559-569 pubmed 出版商
Zhang B, Holmlund M, Lorrain S, Norberg M, Bako L, Fankhauser C, et al. BLADE-ON-PETIOLE proteins act in an E3 ubiquitin ligase complex to regulate PHYTOCHROME INTERACTING FACTOR 4 abundance. elife. 2017;6: pubmed 出版商
Mikkonen E, Haglund C, Holmberg C. Immunohistochemical analysis reveals variations in proteasome tissue expression in C. elegans. PLoS ONE. 2017;12:e0183403 pubmed 出版商
Zhou J, Yao W, Li C, Wu W, Li Q, Liu H. Administration of follicle-stimulating hormone induces autophagy via upregulation of HIF-1? in mouse granulosa cells. Cell Death Dis. 2017;8:e3001 pubmed 出版商
Henriksson E, Huber A, Soto E, Kriebs A, Vaughan M, Duglan D, et al. The Liver Circadian Clock Modulates Biochemical and Physiological Responses to Metformin. J Biol Rhythms. 2017;32:345-358 pubmed 出版商
Becher A, Eiseler T, Porzner M, Walther P, Keil R, Bobrovich S, et al. The armadillo protein p0071 controls KIF3 motor transport. J Cell Sci. 2017;130:3374-3387 pubmed 出版商
Mainardi M, Spinelli M, Scala F, Mattera A, Fusco S, D Ascenzo M, et al. Loss of Leptin-Induced Modulation of Hippocampal Synaptic Trasmission and Signal Transduction in High-Fat Diet-Fed Mice. Front Cell Neurosci. 2017;11:225 pubmed 出版商
Gonnella R, Yadav S, Gilardini Montani M, Granato M, Santarelli R, Garufi A, et al. Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells. Free Radic Biol Med. 2017;112:327-335 pubmed 出版商
Rønning S, Andersen P, Pedersen M, Hollung K. Primary bovine skeletal muscle cells enters apoptosis rapidly via the intrinsic pathway when available oxygen is removed. PLoS ONE. 2017;12:e0182928 pubmed 出版商
Hultin S, Subramani A, Hildebrand S, Zheng Y, Majumdar A, Holmgren L. AmotL2 integrates polarity and junctional cues to modulate cell shape. Sci Rep. 2017;7:7548 pubmed 出版商
Reubens M, Rozenzhak S, Russell P. Multi-BRCT Domain Protein Brc1 Links Rhp18/Rad18 and ?H2A To Maintain Genome Stability during S Phase. Mol Cell Biol. 2017;37: pubmed 出版商
Sun B, Dwivedi N, Bechtel T, Paulsen J, Muth A, Bawadekar M, et al. Citrullination of NF-?B p65 promotes its nuclear localization and TLR-induced expression of IL-1? and TNF?. Sci Immunol. 2017;2: pubmed 出版商
Wan Makhtar W, Browne G, Karountzos A, Stevens C, Alghamdi Y, Bottrill A, et al. Short stretches of rare codons regulate translation of the transcription factor ZEB2 in cancer cells. Oncogene. 2017;36:6640-6648 pubmed 出版商
Govaere O, Petz M, Wouters J, Vandewynckel Y, Scott E, Topal B, et al. The PDGFRα-laminin B1-keratin 19 cascade drives tumor progression at the invasive front of human hepatocellular carcinoma. Oncogene. 2017;36:6605-6616 pubmed 出版商
Choi W, Han J, Kim J, Kim M, Park J, Song B, et al. eIF2α phosphorylation is required to prevent hepatocyte death and liver fibrosis in mice challenged with a high fructose diet. Nutr Metab (Lond). 2017;14:48 pubmed 出版商
Dall Acqua A, Sonego M, Pellizzari I, Pellarin I, Canzonieri V, D Andrea S, et al. CDK6 protects epithelial ovarian cancer from platinum-induced death via FOXO3 regulation. EMBO Mol Med. 2017;9:1415-1433 pubmed 出版商
Artigas N, Gámez B, Cubillos Rojas M, Sánchez de Diego C, Valer J, Pons G, et al. p53 inhibits SP7/Osterix activity in the transcriptional program of osteoblast differentiation. Cell Death Differ. 2017;24:2022-2031 pubmed 出版商
Johnson N, Deck K, Nizzi C, Eisenstein R. A synergistic role of IRP1 and FBXL5 proteins in coordinating iron metabolism during cell proliferation. J Biol Chem. 2017;292:15976-15989 pubmed 出版商
Skowron M, Niegisch G, Albrecht P, Van Koeveringe G, Romano A, Albers P, et al. Various Mechanisms Involve the Nuclear Factor (Erythroid-Derived 2)-Like (NRF2) to Achieve Cytoprotection in Long-Term Cisplatin-Treated Urothelial Carcinoma Cell Lines. Int J Mol Sci. 2017;18: pubmed 出版商
Shirai A, Kawaguchi T, Shimojo H, Muramatsu D, Ishida Yonetani M, Nishimura Y, et al. Impact of nucleic acid and methylated H3K9 binding activities of Suv39h1 on its heterochromatin assembly. elife. 2017;6: pubmed 出版商
Shao J, Gao F, Zhang B, Zhao M, Zhou Y, He J, et al. Aggregation of SND1 in Stress Granules is Associated with the Microtubule Cytoskeleton During Heat Shock Stimulus. Anat Rec (Hoboken). 2017;300:2192-2199 pubmed 出版商
Lander N, Chiurillo M, Vercesi A, Docampo R. Endogenous C-terminal Tagging by CRISPR/Cas9 in Trypanosoma cruzi. Bio Protoc. 2017;7: pubmed 出版商
Hu J, Yang H, Mu J, Lu T, Peng J, Deng X, et al. Nitric Oxide Regulates Protein Methylation during Stress Responses in Plants. Mol Cell. 2017;67:702-710.e4 pubmed 出版商
Feliú A, Bonilla Del Río I, Carrillo Salinas F, Hernández Torres G, Mestre L, Puente N, et al. 2-Arachidonoylglycerol Reduces Proteoglycans and Enhances Remyelination in a Progressive Model of Demyelination. J Neurosci. 2017;37:8385-8398 pubmed 出版商
Kriebs A, Jordan S, Soto E, Henriksson E, Sandate C, Vaughan M, et al. Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity. Proc Natl Acad Sci U S A. 2017;114:8776-8781 pubmed 出版商
Aguilera Gomez A, Zacharogianni M, van Oorschot M, Genau H, Grond R, Veenendaal T, et al. Phospho-Rasputin Stabilization by Sec16 Is Required for Stress Granule Formation upon Amino Acid Starvation. Cell Rep. 2017;20:935-948 pubmed 出版商
Moravcikova E, Krepela E, Donnenberg V, Donnenberg A, Benkova K, Rabachini T, et al. BOK displays cell death-independent tumor suppressor activity in non-small-cell lung carcinoma. Int J Cancer. 2017;141:2050-2061 pubmed 出版商
Margiotta A, Progida C, Bakke O, Bucci C. Characterization of the role of RILP in cell migration. Eur J Histochem. 2017;61:2783 pubmed 出版商
Shi L, Muthusamy N, Smith D, Bergson C. Dynein binds and stimulates axonal motility of the endosome adaptor and NEEP21 family member, calcyon. Int J Biochem Cell Biol. 2017;90:93-102 pubmed 出版商
Genovese I, Fiorillo A, Ilari A, Masciarelli S, Fazi F, Colotti G. Binding of doxorubicin to Sorcin impairs cell death and increases drug resistance in cancer cells. Cell Death Dis. 2017;8:e2950 pubmed 出版商
Guo X, Li F, Xu Z, Yin A, Yin H, Li C, et al. DOCK2 deficiency mitigates HFD-induced obesity by reducing adipose tissue inflammation and increasing energy expenditure. J Lipid Res. 2017;58:1777-1784 pubmed 出版商
Herdman C, Mars J, Stefanovsky V, Tremblay M, Sabourin Felix M, Lindsay H, et al. A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription. PLoS Genet. 2017;13:e1006899 pubmed 出版商
Kopinke D, Roberson E, Reiter J. Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis. Cell. 2017;170:340-351.e12 pubmed 出版商
Delestre Delacour C, Carmon O, Laguerre F, Estay Ahumada C, Courel M, Elias S, et al. Myosin 1b and F-actin are involved in the control of secretory granule biogenesis. Sci Rep. 2017;7:5172 pubmed 出版商
Li X, Lu J, Kan Q, Li X, Fan Q, Li Y, et al. Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells. Sci Rep. 2017;7:5081 pubmed 出版商
Lombard A, Liu C, Armstrong C, Cucchiara V, Gu X, Lou W, et al. ABCB1 Mediates Cabazitaxel-Docetaxel Cross-Resistance in Advanced Prostate Cancer. Mol Cancer Ther. 2017;16:2257-2266 pubmed 出版商
Pérez Garrastachu M, Arluzea J, Andrade R, Díez Torre A, Urtizberea M, Silio M, et al. Nucleoporins redistribute inside the nucleus after cell cycle arrest induced by histone deacetylases inhibition. Nucleus. 2017;8:515-533 pubmed 出版商
Yokota C, Astrand C, Takahashi S, Hagey D, Stenman J. Apolipoprotein C-I mediates Wnt/Ctnnb1 signaling during neural border formation and is required for neural crest development. Int J Dev Biol. 2017;61:415-425 pubmed 出版商
Skouteri M, Hochegger H, Carr A. Characterisation of a stably integrated expression system for exogenous protein expression in DT40. Wellcome Open Res. 2017;2:40 pubmed 出版商
Putranto E, Kinoshita R, Watanabe M, Sadahira T, Murata H, Yamamoto K, et al. Expression of tumor suppressor REIC/Dkk-3 by a newly improved adenovirus vector with insertion of a hTERT promoter at the 3'-side of the transgene. Oncol Lett. 2017;14:1041-1048 pubmed 出版商
Kasai S, Sasaki T, Watanabe A, Nishiya M, Yasuhira S, Shibazaki M, et al. Bcl-2/Bcl-xL inhibitor ABT-737 sensitizes pancreatic ductal adenocarcinoma to paclitaxel-induced cell death. Oncol Lett. 2017;14:903-908 pubmed 出版商
LeBlanc M, Lehmann R. Domain-specific control of germ cell polarity and migration by multifunction Tre1 GPCR. J Cell Biol. 2017;216:2945-2958 pubmed 出版商
Jiang P, Li Y, Poleshko A, Medvedeva V, Baulina N, Zhang Y, et al. The Protein Encoded by the CCDC170 Breast Cancer Gene Functions to Organize the Golgi-Microtubule Network. EBioMedicine. 2017;22:28-43 pubmed 出版商
Martínez Sánchez N, Seoane Collazo P, CONTRERAS C, Varela L, Villarroya J, Rial Pensado E, et al. Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance. Cell Metab. 2017;26:212-229.e12 pubmed 出版商
Rezelj V, Li P, Chaudhary V, Elliott R, Jin D, Brennan B. Differential Antagonism of Human Innate Immune Responses by Tick-Borne Phlebovirus Nonstructural Proteins. mSphere. 2017;2: pubmed 出版商
Avila F, Wolfner M. Cleavage of the Drosophila seminal protein Acp36DE in mated females enhances its sperm storage activity. J Insect Physiol. 2017;101:66-72 pubmed 出版商
Poplutz M, Levikova M, Lüscher Firzlaff J, Lesina M, Algül H, Luscher B, et al. Endotoxin tolerance in mast cells, its consequences for IgE-mediated signalling, and the effects of BCL3 deficiency. Sci Rep. 2017;7:4534 pubmed 出版商
Fan F, Matsunaga K, Wang H, Ishizaki R, Kobayashi E, Kiyonari H, et al. Exophilin-8 assembles secretory granules for exocytosis in the actin cortex via interaction with RIM-BP2 and myosin-VIIa. elife. 2017;6: pubmed 出版商
Cubizolle A, Guillou L, Mollereau B, Hamel C, Brabet P. Fatty acid transport protein 1 regulates retinoid metabolism and photoreceptor development in mouse retina. PLoS ONE. 2017;12:e0180148 pubmed 出版商
Subedi L, Venkatesan R, Kim S. Neuroprotective and Anti-Inflammatory Activities of Allyl Isothiocyanate through Attenuation of JNK/NF-κB/TNF-α Signaling. Int J Mol Sci. 2017;18: pubmed 出版商
Gozdz A, Nikolaienko O, Urbanska M, Cymerman I, Sitkiewicz E, Blazejczyk M, et al. GSK3? and GSK3? Phosphorylate Arc and Regulate its Degradation. Front Mol Neurosci. 2017;10:192 pubmed 出版商
Salemi L, Maitland M, Yefet E, Schild Poulter C. Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex. BMC Cancer. 2017;17:460 pubmed 出版商
Biferi M, Cohen Tannoudji M, Cappelletto A, Giroux B, Roda M, Astord S, et al. A New AAV10-U7-Mediated Gene Therapy Prolongs Survival and Restores Function in an ALS Mouse Model. Mol Ther. 2017;25:2038-2052 pubmed 出版商
Fan Q, Nørgaard R, Bindesbøll C, Lucas C, Dalen K, Babaie E, et al. LXRα Regulates Hepatic ChREBPα Activity and Lipogenesis upon Glucose, but Not Fructose Feeding in Mice. Nutrients. 2017;9: pubmed 出版商
Kang D, Lee D, Lee S, Lee S, Jun Y, Kim Y, et al. Interaction of tankyrase and peroxiredoxin II is indispensable for the survival of colorectal cancer cells. Nat Commun. 2017;8:40 pubmed 出版商
Showalter M, Hatakeyama J, Cajka T, VanderVorst K, Carraway K, Fiehn O. Replication Study: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. elife. 2017;6: pubmed 出版商
Roncacé V, Burattini C, Stagni F, Guidi S, Giacomini A, Emili M, et al. Neuroanatomical alterations and synaptic plasticity impairment in the perirhinal cortex of the Ts65Dn mouse model of Down syndrome. Neurobiol Dis. 2017;106:89-100 pubmed 出版商
Hindriksen S, Bramer A, Truong M, Vromans M, Post J, Verlaan Klink I, et al. Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells. PLoS ONE. 2017;12:e0179514 pubmed 出版商
Valigurová A, Vaškovicová N, Diakin A, Paskerova G, Simdyanov T, Kováčiková M. Motility in blastogregarines (Apicomplexa): Native and drug-induced organisation of Siedleckia nematoides cytoskeletal elements. PLoS ONE. 2017;12:e0179709 pubmed 出版商
Prusty A, Meduri R, Prusty B, Vanselow J, Schlosser A, Fischer U. Impaired spliceosomal UsnRNP assembly leads to Sm mRNA down-regulation and Sm protein degradation. J Cell Biol. 2017;216:2391-2407 pubmed 出版商
Gunarta I, Li R, Nakazato R, Suzuki R, Boldbaatar J, Suzuki T, et al. Critical role of glioma-associated oncogene homolog 1 in maintaining invasive and mesenchymal-like properties of melanoma cells. Cancer Sci. 2017;108:1602-1611 pubmed 出版商
Newkirk S, Lee S, Grandi F, Gaysinskaya V, Rosser J, Vanden Berg N, et al. Intact piRNA pathway prevents L1 mobilization in male meiosis. Proc Natl Acad Sci U S A. 2017;114:E5635-E5644 pubmed 出版商
Epstein Shochet G, Brook E, Israeli Shani L, Edelstein E, Shitrit D. Fibroblast paracrine TNF-? signaling elevates integrin A5 expression in idiopathic pulmonary fibrosis (IPF). Respir Res. 2017;18:122 pubmed 出版商
Kraus R, Yu X, Cordes B, Sathiamoorthi S, Iempridee T, Nawandar D, et al. Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter. PLoS Pathog. 2017;13:e1006404 pubmed 出版商
Hori I, Otomo T, Nakashima M, Miya F, Negishi Y, Shiraishi H, et al. Defects in autophagosome-lysosome fusion underlie Vici syndrome, a neurodevelopmental disorder with multisystem involvement. Sci Rep. 2017;7:3552 pubmed 出版商
Qi N, Shi Y, Zhang R, Zhu W, Yuan B, Li X, et al. Multiple truncated isoforms of MAVS prevent its spontaneous aggregation in antiviral innate immune signalling. Nat Commun. 2017;8:15676 pubmed 出版商
Karki M, Keyhaninejad N, Shuster C. Precocious centriole disengagement and centrosome fragmentation induced by mitotic delay. Nat Commun. 2017;8:15803 pubmed 出版商
Terry S, Manganaro L, Cuesta Dominguez A, Brinzevich D, Simon V, Mulder L. Expression of HERV-K108 envelope interferes with HIV-1 production. Virology. 2017;509:52-59 pubmed 出版商
Shen M, Jiang Y, Guan Z, Cao Y, Li L, Liu H, et al. Protective mechanism of FSH against oxidative damage in mouse ovarian granulosa cells by repressing autophagy. Autophagy. 2017;13:1364-1385 pubmed 出版商
Jo M, Chung A, Yachie N, Seo M, Jeon H, Nam Y, et al. Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target. Genome Res. 2017;27:1487-1500 pubmed 出版商
Bassat E, Mutlak Y, Genzelinakh A, Shadrin I, Baruch Umansky K, Yifa O, et al. The extracellular matrix protein agrin promotes heart regeneration in mice. Nature. 2017;547:179-184 pubmed 出版商
Tai Nagara I, Yoshikawa Y, Numata N, Ando T, Okabe K, Sugiura Y, et al. Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling. Development. 2017;144:2392-2401 pubmed 出版商
Inano S, Sato K, Katsuki Y, Kobayashi W, Tanaka H, Nakajima K, et al. RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination. Mol Cell. 2017;66:622-634.e8 pubmed 出版商
Salova A, Belyaeva T, Leontieva E, Kornilova E. EGF receptor lysosomal degradation is delayed in the cells stimulated with EGF-Quantum dot bioconjugate but earlier key events of endocytic degradative pathway are similar to that of native EGF. Oncotarget. 2017;8:44335-44350 pubmed 出版商
Takata K, Reh S, Yousefzadeh M, Zelazowski M, Bhetawal S, Trono D, et al. Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance. PLoS Genet. 2017;13:e1006818 pubmed 出版商
Quirós P, Prado M, Zamboni N, D Amico D, Williams R, Finley D, et al. Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals. J Cell Biol. 2017;216:2027-2045 pubmed 出版商
Bakula D, Müller A, Zuleger T, Takacs Z, Franz Wachtel M, Thost A, et al. WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy. Nat Commun. 2017;8:15637 pubmed 出版商
Hengeveld R, Vromans M, Vleugel M, Hadders M, Lens S. Inner centromere localization of the CPC maintains centromere cohesion and allows mitotic checkpoint silencing. Nat Commun. 2017;8:15542 pubmed 出版商
Cho J, Kim S, Seo Y, Park S, Park B, Kim J, et al. The p90 ribosomal S6 kinase-UBR5 pathway controls Toll-like receptor signaling via miRNA-induced translational inhibition of tumor necrosis factor receptor-associated factor 3. J Biol Chem. 2017;292:11804-11814 pubmed 出版商
Yost S, de Wolf B, Hanks S, Zachariou A, Marcozzi C, Clarke M, et al. Biallelic TRIP13 mutations predispose to Wilms tumor and chromosome missegregation. Nat Genet. 2017;49:1148-1151 pubmed 出版商
Pattarozzi A, Carra E, Favoni R, Würth R, Marubbi D, Filiberti R, et al. The inhibition of FGF receptor 1 activity mediates sorafenib antiproliferative effects in human malignant pleural mesothelioma tumor-initiating cells. Stem Cell Res Ther. 2017;8:119 pubmed 出版商
Andres L, Blong I, Evans A, Rumachik N, Yamaguchi T, Pham N, et al. Chemical Modulation of Protein O-GlcNAcylation via OGT Inhibition Promotes Human Neural Cell Differentiation. ACS Chem Biol. 2017;12:2030-2039 pubmed 出版商
Herrington K, Trinh A, Dang C, O Shaughnessy E, Hahn K, Gratton E, et al. Spatial analysis of Cdc42 activity reveals a role for plasma membrane-associated Cdc42 in centrosome regulation. Mol Biol Cell. 2017;28:2135-2145 pubmed 出版商
Sala V, Gallo S, Gatti S, Vigna E, Ponzetto A, Crepaldi T. Anti-Differentiation Effect of Oncogenic Met Receptor in Terminally-Differentiated Myotubes. Biomedicines. 2015;3:124-137 pubmed 出版商
Yonezawa T, Takahashi H, Shikata S, Liu X, Tamura M, Asada S, et al. The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1. J Biol Chem. 2017;292:12528-12541 pubmed 出版商
Jeske M, Müller C, Ephrussi A. The LOTUS domain is a conserved DEAD-box RNA helicase regulator essential for the recruitment of Vasa to the germ plasm and nuage. Genes Dev. 2017;31:939-952 pubmed 出版商
Juuti Uusitalo K, Koskela A, Kivinen N, Viiri J, Hyttinen J, Reinisalo M, et al. Autophagy Regulates Proteasome Inhibitor-Induced Pigmentation in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells. Int J Mol Sci. 2017;18: pubmed 出版商
Guilliam T, Brissett N, Ehlinger A, Keen B, Kolesar P, Taylor E, et al. Molecular basis for PrimPol recruitment to replication forks by RPA. Nat Commun. 2017;8:15222 pubmed 出版商
Chugh P, Clark A, Smith M, Cassani D, Dierkes K, Ragab A, et al. Actin cortex architecture regulates cell surface tension. Nat Cell Biol. 2017;19:689-697 pubmed 出版商
Amorim R, Daher I, Arcangelo F, Bellini M, Orcini W, Sarria G, et al. Short-term effects of green tea chronotherapy on the metabolic homeostasis of mice on different diets. Genet Mol Res. 2017;16: pubmed 出版商
Portugal R, Bauer A, Keil G. Selection of differently temporally regulated African swine fever virus promoters with variable expression activities and their application for transient and recombinant virus mediated gene expression. Virology. 2017;508:70-80 pubmed 出版商
Liu C, Armstrong C, Lou W, Lombard A, Cucchiara V, Gu X, et al. Niclosamide and Bicalutamide Combination Treatment Overcomes Enzalutamide- and Bicalutamide-Resistant Prostate Cancer. Mol Cancer Ther. 2017;16:1521-1530 pubmed 出版商
Varjak M, Maringer K, Watson M, Sreenu V, Fredericks A, Pondeville E, et al. Aedes aegypti Piwi4 Is a Noncanonical PIWI Protein Involved in Antiviral Responses. mSphere. 2017;2: pubmed 出版商
Nousch M, Minasaki R, Eckmann C. Polyadenylation is the key aspect of GLD-2 function in C. elegans. RNA. 2017;23:1180-1187 pubmed 出版商
Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, et al. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. 2017;545:365-369 pubmed 出版商
Bellissimo T, Ganci F, Gallo E, Sacconi A, Tito C, De Angelis L, et al. Thymic Epithelial Tumors phenotype relies on miR-145-5p epigenetic regulation. Mol Cancer. 2017;16:88 pubmed 出版商
Girolimetti G, Guerra F, Iommarini L, Kurelac I, Vergara D, Maffia M, et al. Platinum-induced mitochondrial DNA mutations confer lower sensitivity to paclitaxel by impairing tubulin cytoskeletal organization. Hum Mol Genet. 2017;26:2961-2974 pubmed 出版商
da Silva M, Peçanha F, de Oliveira A, da Silva W. 4-Phenyl butyric acid increases particulate hexokinase activity and protects against ROS injury in L6 myotubes. Life Sci. 2017;179:98-102 pubmed 出版商
Rogell B, Fischer B, Rettel M, Krijgsveld J, Castello A, Hentze M. Specific RNP capture with antisense LNA/DNA mixmers. RNA. 2017;23:1290-1302 pubmed 出版商
Ash P, Stanford E, Al Abdulatif A, Ramirez Cardenas A, Ballance H, Boudeau S, et al. Dioxins and related environmental contaminants increase TDP-43 levels. Mol Neurodegener. 2017;12:35 pubmed 出版商
Gu Y, Cohn S, Christie A, McKenzie T, Wolff N, Do Q, et al. Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade. Cancer Discov. 2017;7:900-917 pubmed 出版商
Shi Y, Yuan B, Zhu W, Zhang R, Li L, Hao X, et al. Ube2D3 and Ube2N are essential for RIG-I-mediated MAVS aggregation in antiviral innate immunity. Nat Commun. 2017;8:15138 pubmed 出版商
Vink E, Smiley J, Mohr I. Subversion of Host Responses to Energy Insufficiency by Us3 Supports Herpes Simplex Virus 1 Replication during Stress. J Virol. 2017;91: pubmed 出版商
Gordon M, D Amato N, Gu H, Babbs B, Wulfkuhle J, Petricoin E, et al. Synergy between Androgen Receptor Antagonism and Inhibition of mTOR and HER2 in Breast Cancer. Mol Cancer Ther. 2017;16:1389-1400 pubmed 出版商
Amankulor N, Kim Y, Arora S, Kargl J, Szulzewsky F, Hanke M, et al. Mutant IDH1 regulates the tumor-associated immune system in gliomas. Genes Dev. 2017;31:774-786 pubmed 出版商
Moleirinho S, Hoxha S, Mandati V, Curtale G, Troutman S, Ehmer U, et al. Regulation of localization and function of the transcriptional co-activator YAP by angiomotin. elife. 2017;6: pubmed 出版商
Yamamoto Y, Uno Y, Sha E, Ikegami K, Ishii N, Dohmae N, et al. Asymmetry in the function and dynamics of the cytosolic group II chaperonin CCT/TRiC. PLoS ONE. 2017;12:e0176054 pubmed 出版商
Smith N, Davies P, Levin T, Gallagher A, Keene D, Sengupta S, et al. Cell Adhesion Molecule CD166/ALCAM Functions Within the Crypt to Orchestrate Murine Intestinal Stem Cell Homeostasis. Cell Mol Gastroenterol Hepatol. 2017;3:389-409 pubmed 出版商
Bhalla M, Law D, Dowd G, Ireton K. Host Serine/Threonine Kinases mTOR and Protein Kinase C-? Promote InlB-Mediated Entry of Listeria monocytogenes. Infect Immun. 2017;85: pubmed 出版商
Liu Y, Lin H, Lai S, Huang C, Huang B, Chen P, et al. MiR-181b modulates EGFR-dependent VCAM-1 expression and monocyte adhesion in glioblastoma. Oncogene. 2017;36:5006-5022 pubmed 出版商
Fernández Laso V, Sastre C, Méndez Barbero N, Egido J, Martin Ventura J, Gomez Guerrero C, et al. TWEAK blockade decreases atherosclerotic lesion size and progression through suppression of STAT1 signaling in diabetic mice. Sci Rep. 2017;7:46679 pubmed 出版商
Dragano N, Solon C, Ramalho A, de Moura R, Razolli D, Christiansen E, et al. Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation. J Neuroinflammation. 2017;14:91 pubmed 出版商
Luo S, Cai S, Maxwell S, Yue D, Zhu W, Qiao K, et al. Novel mutations in the C-terminal region of GMPPB causing limb-girdle muscular dystrophy overlapping with congenital myasthenic syndrome. Neuromuscul Disord. 2017;27:557-564 pubmed 出版商
Cheng S, Wani W, Hottman D, Jeong A, Cao D, LeBlanc K, et al. Haplodeficiency of Cathepsin D does not affect cerebral amyloidosis and autophagy in APP/PS1 transgenic mice. J Neurochem. 2017;142:297-304 pubmed 出版商
Gumy L, Katrukha E, Grigoriev I, Jaarsma D, Kapitein L, Akhmanova A, et al. MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory Neurons. Neuron. 2017;94:347-362.e7 pubmed 出版商
Andreone B, Chow B, Tata A, Lacoste B, Ben Zvi A, Bullock K, et al. Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis. Neuron. 2017;94:581-594.e5 pubmed 出版商
Choquet K, Yang S, Moir R, Forget D, Lariviere R, Bouchard A, et al. Absence of neurological abnormalities in mice homozygous for the Polr3a G672E hypomyelinating leukodystrophy mutation. Mol Brain. 2017;10:13 pubmed 出版商
Montellese C, Montel Lehry N, Henras A, Kutay U, Gleizes P, O Donohue M. Poly(A)-specific ribonuclease is a nuclear ribosome biogenesis factor involved in human 18S rRNA maturation. Nucleic Acids Res. 2017;45:6822-6836 pubmed 出版商
Umegawachi T, Yoshida H, Koshida H, Yamada M, Ohkawa Y, Sato T, et al. Control of tissue size and development by a regulatory element in the yorkie 3'UTR. Am J Cancer Res. 2017;7:673-687 pubmed
Zhou W, De Iuliis G, Turner A, Reid A, Anderson A, McCluskey A, et al. Developmental expression of the dynamin family of mechanoenzymes in the mouse epididymis. Biol Reprod. 2017;96:159-173 pubmed 出版商
Elayyan J, Lee E, Gabay O, Smith C, Qiq O, Reich E, et al. LEF1-mediated MMP13 gene expression is repressed by SIRT1 in human chondrocytes. FASEB J. 2017;31:3116-3125 pubmed 出版商
Sidorchuk Y, Deineko E. Cytoskeletal mechanisms in positioning of the second-division spindles and meiotic restitution in tobacco (Nicotiana tabacum L.) microsporogenesis. Cell Biol Int. 2017;41:669-679 pubmed 出版商
López Soop G, Rønningen T, Rogala A, Richartz N, Blomhoff H, Thiede B, et al. AKAP95 interacts with nucleoporin TPR in mitosis and is important for the spindle assembly checkpoint. Cell Cycle. 2017;16:947-956 pubmed 出版商
Arrant A, Filiano A, Unger D, Young A, Roberson E. Restoring neuronal progranulin reverses deficits in a mouse model of frontotemporal dementia. Brain. 2017;140:1447-1465 pubmed 出版商
Ranieri D, Proietti S, Dinicola S, Masiello M, Rosato B, Ricci G, et al. Simulated microgravity triggers epithelial mesenchymal transition in human keratinocytes. Sci Rep. 2017;7:538 pubmed 出版商
Franz A, Shlyueva D, Brunner E, Stark A, Basler K. Probing the canonicity of the Wnt/Wingless signaling pathway. PLoS Genet. 2017;13:e1006700 pubmed 出版商
Pereira M, Mahú I, Seixas E, Martínez Sánchez N, Kubasova N, Pirzgalska R, et al. A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages. Nat Commun. 2017;8:14967 pubmed 出版商
Yeh Y, Liou J, Lee Y, Lin J, Huang H. MPT0B002, a novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells. Invest New Drugs. 2017;35:427-435 pubmed 出版商
Otsubo K, Goto H, Nishio M, Kawamura K, Yanagi S, Nishie W, et al. MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation. Oncogene. 2017;36:4201-4211 pubmed 出版商
Buonocore F, Kühnen P, Suntharalingham J, Del Valle I, Digweed M, Stachelscheid H, et al. Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans. J Clin Invest. 2017;127:1700-1713 pubmed 出版商
Martins H, Bazotte R, Vicentini G, Lima M, Guarnier F, Hermes Uliana C, et al. l-Glutamine supplementation promotes an improved energetic balance in Walker-256 tumor-bearing rats. Tumour Biol. 2017;39:1010428317695960 pubmed 出版商
Delbarre E, Ivanauskiene K, Spirkoski J, Shah A, Vekterud K, Moskaug J, et al. PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX. Genome Res. 2017;27:913-921 pubmed 出版商
Mi C, Ma J, Wang K, Zuo H, Wang Z, Li M, et al. Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1? via the mTOR/p70S6K/4E-BP1 and MAPK pathways. J Ethnopharmacol. 2017;203:27-38 pubmed 出版商
Baar M, Brandt R, Putavet D, Klein J, Derks K, Bourgeois B, et al. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell. 2017;169:132-147.e16 pubmed 出版商
Shi X, Hapiak V, Zheng J, Muller Greven J, Bowman D, Lingerak R, et al. A role of the SAM domain in EphA2 receptor activation. Sci Rep. 2017;7:45084 pubmed 出版商
Mercado Matos J, Clark J, Piper A, Janusis J, Shaw L. Differential involvement of the microtubule cytoskeleton in insulin receptor substrate 1 (IRS-1) and IRS-2 signaling to AKT determines the response to microtubule disruption in breast carcinoma cells. J Biol Chem. 2017;292:7806-7816 pubmed 出版商
Gama J, Pereira C, Simões P, Celestino R, Reis R, Barbosa D, et al. Molecular mechanism of dynein recruitment to kinetochores by the Rod-Zw10-Zwilch complex and Spindly. J Cell Biol. 2017;216:943-960 pubmed 出版商
Donato V, Bonora M, Simoneschi D, Sartini D, Kudo Y, Saraf A, et al. The TDH-GCN5L1-Fbxo15-KBP axis limits mitochondrial biogenesis in mouse embryonic stem cells. Nat Cell Biol. 2017;19:341-351 pubmed 出版商
Sechler M, Parrish J, Birks D, Jedlicka P. The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasis. Oncogene. 2017;36:4150-4160 pubmed 出版商
Grasso S, Chapelle J, Salemme V, Aramu S, Russo I, Vitale N, et al. The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries. Nat Commun. 2017;8:14797 pubmed 出版商
Balmer D, Bapst Wicht L, Pyakurel A, Emery M, Nanchen N, Bochet C, et al. Bis-Retinoid A2E Induces an Increase of Basic Fibroblast Growth Factor via Inhibition of Extracellular Signal-Regulated Kinases 1/2 Pathway in Retinal Pigment Epithelium Cells and Facilitates Phagocytosis. Front Aging Neurosci. 2017;9:43 pubmed 出版商
Dos Santos A, Terra L, Wailemann R, Oliveira T, Gomes V, Mineiro M, et al. Methylene blue photodynamic therapy induces selective and massive cell death in human breast cancer cells. BMC Cancer. 2017;17:194 pubmed 出版商
Hosogane M, Bosu L, Fukumoto E, Yamada H, Sato S, Nakayama K. Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells. Genes Cells. 2017;22:360-375 pubmed 出版商
Kashihara T, Nakada T, Kojima K, Takeshita T, Yamada M. Angiotensin II activates CaV 1.2 Ca2+ channels through ?-arrestin2 and casein kinase 2 in mouse immature cardiomyocytes. J Physiol. 2017;595:4207-4225 pubmed 出版商
Chien M, Chang W, Lee W, Chang Y, Lai T, Chan D, et al. A Fas Ligand (FasL)-Fused Humanized Antibody Against Tumor-Associated Glycoprotein 72 Selectively Exhibits the Cytotoxic Effect Against Oral Cancer Cells with a Low FasL/Fas Ratio. Mol Cancer Ther. 2017;16:1102-1113 pubmed 出版商
Malonis R, Fu W, Jelcic M, Thompson M, Canter B, Tsikitis M, et al. RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling. J Biol Chem. 2017;292:7435-7451 pubmed 出版商
Dubey D, McRae P, Rankin Gee E, Baranov E, Wandrey L, Rogers S, et al. Increased metalloproteinase activity in the hippocampus following status epilepticus. Epilepsy Res. 2017;132:50-58 pubmed 出版商
Peled M, Nishi H, Weinstock A, Barrett T, Zhou F, Quezada A, et al. A wild-type mouse-based model for the regression of inflammation in atherosclerosis. PLoS ONE. 2017;12:e0173975 pubmed 出版商
Petit M, Koziel R, Etemad S, Pircher H, Jansen Durr P. Depletion of oxaloacetate decarboxylase FAHD1 inhibits mitochondrial electron transport and induces cellular senescence in human endothelial cells. Exp Gerontol. 2017;92:7-12 pubmed 出版商
Nassal M, Wan X, Dale Z, Deschênes I, Wilson L, Piktel J. Mild hypothermia preserves myocardial conduction during ischemia by maintaining gap junction intracellular communication and Na+ channel function. Am J Physiol Heart Circ Physiol. 2017;312:H886-H895 pubmed 出版商
Roca Ho H, Riera M, Palau V, Pascual J, Soler M. Characterization of ACE and ACE2 Expression within Different Organs of the NOD Mouse. Int J Mol Sci. 2017;18: pubmed 出版商
Valitsky M, Hoffman A, Unterman T, Bar Tana J. Insulin sensitizer prevents and ameliorates experimental type 1 diabetes. Am J Physiol Endocrinol Metab. 2017;313:E672-E680 pubmed 出版商
Subedi L, Ji E, Shin D, Jin J, Yeo J, Kim S. Equol, a Dietary Daidzein Gut Metabolite Attenuates Microglial Activation and Potentiates Neuroprotection In Vitro. Nutrients. 2017;9: pubmed 出版商
Bertapelle C, Polese G, Di Cosmo A. Enriched Environment Increases PCNA and PARP1 Levels in Octopus vulgaris Central Nervous System: First Evidence of Adult Neurogenesis in Lophotrochozoa. J Exp Zool B Mol Dev Evol. 2017;328:347-359 pubmed 出版商
Kuzniar A, Laffeber C, Eppink B, Bezstarosti K, Dekkers D, Woelders H, et al. Semi-quantitative proteomics of mammalian cells upon short-term exposure to non-ionizing electromagnetic fields. PLoS ONE. 2017;12:e0170762 pubmed 出版商
Frémont S, Hammich H, Bai J, Wioland H, Klinkert K, Rocancourt M, et al. Oxidation of F-actin controls the terminal steps of cytokinesis. Nat Commun. 2017;8:14528 pubmed 出版商
Liu M, Ba Z, Costa Nunes P, Wei W, Li L, Kong F, et al. IDN2 Interacts with RPA and Facilitates DNA Double-Strand Break Repair by Homologous Recombination in Arabidopsis. Plant Cell. 2017;29:589-599 pubmed 出版商
Afiyatullov S, Leshchenko E, Berdyshev D, Sobolevskaya M, Antonov A, Denisenko V, et al. Zosteropenillines: Polyketides from the MarineDerived Fungus Penicillium thomii. Mar Drugs. 2017;15: pubmed 出版商
Crawford Parks T, Marcellus K, Langill J, Ravel Chapuis A, Michaud J, Cowan K, et al. Novel Roles for Staufen1 in Embryonal and Alveolar Rhabdomyosarcoma via c-myc-dependent and -independent events. Sci Rep. 2017;7:42342 pubmed 出版商
Bellanger A, Donini C, Vendrell J, Lavaud J, Machuca Gayet I, Ruel M, et al. The critical role of the ZNF217 oncogene in promoting breast cancer metastasis to the bone. J Pathol. 2017;242:73-89 pubmed 出版商
Christenson J, Butterfield K, Spoelstra N, Norris J, Josan J, Pollock J, et al. MMTV-PyMT and Derived Met-1 Mouse Mammary Tumor Cells as Models for Studying the Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression. Horm Cancer. 2017;8:69-77 pubmed 出版商
Ripa R, Dolfi L, Terrigno M, Pandolfini L, Savino A, Arcucci V, et al. MicroRNA miR-29 controls a compensatory response to limit neuronal iron accumulation during adult life and aging. BMC Biol. 2017;15:9 pubmed 出版商
Oikawa K, Mizusaki A, Takanashi M, Ozaki T, Sato F, Kuroda M, et al. PRG4 expression in myxoid liposarcoma maintains tumor cell growth through suppression of an antitumor cytokine IL-24. Biochem Biophys Res Commun. 2017;485:209-214 pubmed 出版商
Reynolds J, Bicknell L, Carroll P, Higgs M, Shaheen R, Murray J, et al. Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism. Nat Genet. 2017;49:537-549 pubmed 出版商
Shah P, Dupre T, Siskind L, Beverly L. Common cytotoxic chemotherapeutics induce epithelial-mesenchymal transition (EMT) downstream of ER stress. Oncotarget. 2017;8:22625-22639 pubmed 出版商
Shumilov A, Tsai M, Schlosser Y, Kratz A, Bernhardt K, Fink S, et al. Epstein-Barr virus particles induce centrosome amplification and chromosomal instability. Nat Commun. 2017;8:14257 pubmed 出版商
Kang S, Yi H, Choi M, Ryu M, Jung S, Chung H, et al. ANGPTL6 expression is coupled with mitochondrial OXPHOS function to regulate adipose FGF21. J Endocrinol. 2017;233:105-118 pubmed 出版商
Nawandar D, Ohashi M, Djavadian R, Barlow E, Makielski K, Ali A, et al. Differentiation-Dependent LMP1 Expression Is Required for Efficient Lytic Epstein-Barr Virus Reactivation in Epithelial Cells. J Virol. 2017;91: pubmed 出版商
Gómez Grau M, Albaigès J, Casas J, Auladell C, Dierssen M, Vilageliu L, et al. New murine Niemann-Pick type C models bearing a pseudoexon-generating mutation recapitulate the main neurobehavioural and molecular features of the disease. Sci Rep. 2017;7:41931 pubmed 出版商
Baxley R, Bullard J, Klein M, Fell A, Morales Rosado J, Duan T, et al. Deciphering the DNA code for the function of the Drosophila polydactyl zinc finger protein Suppressor of Hairy-wing. Nucleic Acids Res. 2017;45:4463-4478 pubmed 出版商
Sutton J, Blount J, Libohova K, Tsou W, Joshi G, Paulson H, et al. Interaction of the polyglutamine protein ataxin-3 with Rad23 regulates toxicity in Drosophila models of Spinocerebellar Ataxia Type 3. Hum Mol Genet. 2017;26:1419-1431 pubmed 出版商
Zhao L, Quinn A, Ng E, Veyrunes F, Koopman P. Reduced Activity of SRY and its Target Enhancer Sox9-TESCO in a Mouse Species with X*Y Sex Reversal. Sci Rep. 2017;7:41378 pubmed 出版商
Ohoka N, Okuhira K, Ito M, Nagai K, Shibata N, Hattori T, et al. In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs). J Biol Chem. 2017;292:4556-4570 pubmed 出版商
Zhu C, Yu Y, Montani J, Ming X, Yang Z. Arginase-I enhances vascular endothelial inflammation and senescence through eNOS-uncoupling. BMC Res Notes. 2017;10:82 pubmed 出版商
Hu Y, O Boyle K, Auer J, Raju S, You F, Wang P, et al. Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα. PLoS Pathog. 2017;13:e1006187 pubmed 出版商
He Y, Northey J, Pelletier A, Kos Z, Meunier L, Haibe Kains B, et al. The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer. Oncogene. 2017;36:3490-3503 pubmed 出版商
Schou K, Mogensen J, Morthorst S, Nielsen B, Aleliunaite A, Serra Marques A, et al. KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling. Nat Commun. 2017;8:14177 pubmed 出版商
Alt A, Dang H, Wells O, Polo L, Smith M, McGregor G, et al. Specialized interfaces of Smc5/6 control hinge stability and DNA association. Nat Commun. 2017;8:14011 pubmed 出版商
Wang X, Du H, Li L, Shao D, Zhong X, Hu Y, et al. Increased expression of S100A6 promotes cell proliferation in gastric cancer cells. Oncol Lett. 2017;13:222-230 pubmed 出版商
Chang Y, Huang Y. Midbody localization of vinexin recruits rhotekin to facilitate cytokinetic abscission. Cell Cycle. 2017;16:2046-2057 pubmed 出版商
Kim M, Deng H, Wong Y, Siddique T, Krainc D. The Parkinson's disease-linked protein TMEM230 is required for Rab8a-mediated secretory vesicle trafficking and retromer trafficking. Hum Mol Genet. 2017;26:729-741 pubmed 出版商
Jarad M, Kuczynski E, Morrison J, Viloria Petit A, Coomber B. Release of endothelial cell associated VEGFR2 during TGF-β modulated angiogenesis in vitro. BMC Cell Biol. 2017;18:10 pubmed 出版商
Andreev J, Thambi N, Perez Bay A, Delfino F, Martin J, Kelly M, et al. Bispecific Antibodies and Antibody-Drug Conjugates (ADCs) Bridging HER2 and Prolactin Receptor Improve Efficacy of HER2 ADCs. Mol Cancer Ther. 2017;16:681-693 pubmed 出版商
Lucena R, Alcaide Gavilán M, Anastasia S, Kellogg D. Wee1 and Cdc25 are controlled by conserved PP2A-dependent mechanisms in fission yeast. Cell Cycle. 2017;16:428-435 pubmed 出版商
Flanagan A, Stavenschi E, Basavaraju S, Gaboriau D, Hoey D, Morrison C. Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification. Mol Biol Cell. 2017;28:736-745 pubmed 出版商
Serrano Pozo A, Sánchez García M, Heras Garvín A, March Díaz R, Navarro V, Vizuete M, et al. Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo. PLoS ONE. 2017;12:e0170345 pubmed 出版商
Castañeda Bueno M, Arroyo J, Zhang J, Puthumana J, Yarborough O, Shibata S, et al. Phosphorylation by PKC and PKA regulate the kinase activity and downstream signaling of WNK4. Proc Natl Acad Sci U S A. 2017;114:E879-E886 pubmed 出版商
Coccia M, Rossi A, Riccio A, Trotta E, Santoro M. Human NF-κB repressing factor acts as a stress-regulated switch for ribosomal RNA processing and nucleolar homeostasis surveillance. Proc Natl Acad Sci U S A. 2017;114:1045-1050 pubmed 出版商
Zhang L, Peng S, Dai X, Gan W, Nie X, Wei W, et al. Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells. Cancer Lett. 2017;390:11-20 pubmed 出版商
Wienholz F, Vermeulen W, Marteijn J. Amplification of unscheduled DNA synthesis signal enables fluorescence-based single cell quantification of transcription-coupled nucleotide excision repair. Nucleic Acids Res. 2017;45:e68 pubmed 出版商
Zhou J, Tang Y, Xie Z, Lu J, Deng J, Huang X, et al. AKT activation was not essential for hepatocellular carcinoma cell survival under glucose deprivation. Anticancer Drugs. 2017;28:427-435 pubmed 出版商
Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar -, et al. DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas. Cell. 2016;167:1264-1280.e18 pubmed 出版商
Juan Mateu J, Rech T, Villate O, Lizárraga Mollinedo E, Wendt A, Turatsinze J, et al. Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival. J Biol Chem. 2017;292:3466-3480 pubmed 出版商
Peuchant E, Bats M, Moranvillier I, Lepoivre M, Guitton J, Wendum D, et al. Metastasis suppressor NM23 limits oxidative stress in mammals by preventing activation of stress-activated protein kinases/JNKs through its nucleoside diphosphate kinase activity. FASEB J. 2017;31:1531-1546 pubmed 出版商
Peirs S, Frismantas V, Matthijssens F, Van Loocke W, Pieters T, Vandamme N, et al. Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia. Leukemia. 2017;31:2037-2047 pubmed 出版商
Tanaka Y, Suzuki G, Matsuwaki T, Hosokawa M, Serrano G, Beach T, et al. Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes. Hum Mol Genet. 2017;26:969-988 pubmed 出版商
Sansregret L, Patterson J, Dewhurst S, Lopez Garcia C, Koch A, McGranahan N, et al. APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability. Cancer Discov. 2017;7:218-233 pubmed 出版商
Gao F, Shi L, Hines T, Hebbar S, Neufeld K, Smith D. Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein. Mol Biol Cell. 2017;28:587-599 pubmed 出版商
Vega Rubin de Celis S, Peña Llopis S, Konda M, Brugarolas J. Multistep regulation of TFEB by MTORC1. Autophagy. 2017;13:464-472 pubmed 出版商
Sunami Y, Araki M, Kan S, Ito A, Hironaka Y, Imai M, et al. Histone Acetyltransferase p300/CREB-binding Protein-associated Factor (PCAF) Is Required for All-trans-retinoic Acid-induced Granulocytic Differentiation in Leukemia Cells. J Biol Chem. 2017;292:2815-2829 pubmed 出版商
Shimizu K, Fukushima H, Ogura K, Lien E, Nihira N, Zhang J, et al. The SCF?-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis. Sci Signal. 2017;10: pubmed 出版商
Bernard K, Logsdon N, Miguel V, Benavides G, Zhang J, Carter A, et al. NADPH Oxidase 4 (Nox4) Suppresses Mitochondrial Biogenesis and Bioenergetics in Lung Fibroblasts via a Nuclear Factor Erythroid-derived 2-like 2 (Nrf2)-dependent Pathway. J Biol Chem. 2017;292:3029-3038 pubmed 出版商
Sahoo M, Gaikwad S, Khuperkar D, Ashok M, Helen M, Yadav S, et al. Nup358 binds to AGO proteins through its SUMO-interacting motifs and promotes the association of target mRNA with miRISC. EMBO Rep. 2017;18:241-263 pubmed 出版商
Kozlova N, Wottawa M, Katschinski D, Kristiansen G, Kietzmann T. Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer. Oncotarget. 2017;8:9885-9898 pubmed 出版商
Shao M, Ge G, Liu W, Xiao J, Xia H, Fan Y, et al. Characterization and phylogenetic analysis of Krüppel-like transcription factor (KLF) gene family in tree shrews (Tupaia belangeri chinensis). Oncotarget. 2017;8:16325-16339 pubmed 出版商
Lu J, Chiang Y, Lin Y, Chang Y, Lu C, Chen T, et al. Disruption of Lipid Raft Function Increases Expression and Secretion of Monocyte Chemoattractant Protein-1 in 3T3-L1 Adipocytes. PLoS ONE. 2016;11:e0169005 pubmed 出版商
de Pauli L, Santos E, Daher Arcangelo F, Orcini W, Peruquetti R. Differential expression of the nucleolar protein fibrillarin during mammalian spermatogenesis and its probable association with chromatoid body components. Micron. 2017;94:37-45 pubmed 出版商
Holland P, Knævelsrud H, Søreng K, Mathai B, Lystad A, Pankiv S, et al. HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels. Nat Commun. 2016;7:13889 pubmed 出版商
van de Ven R, de Groot J, Park D, van Domselaar R, de Jong D, Szuhai K, et al. p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis. Nat Commun. 2016;7:13874 pubmed 出版商
Wille C, Li Y, Rui L, JOHANNSEN E, Kenney S. Restricted TET2 Expression in Germinal Center Type B Cells Promotes Stringent Epstein-Barr Virus Latency. J Virol. 2017;91: pubmed 出版商
Karlsson T, Krakstad C, Tangen I, Hoivik E, Pollock P, Salvesen H, et al. Endometrial cancer cells exhibit high expression of p110β and its selective inhibition induces variable responses on PI3K signaling, cell survival and proliferation. Oncotarget. 2017;8:3881-3894 pubmed 出版商
Vakana E, Pratt S, Blosser W, Dowless M, Simpson N, Yuan X, et al. LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer. Oncotarget. 2017;8:9251-9266 pubmed 出版商
Zhao X, Khurana S, Charkraborty S, Tian Y, Sedor J, Bruggman L, et al. ? Actinin 4 (ACTN4) Regulates Glucocorticoid Receptor-mediated Transactivation and Transrepression in Podocytes. J Biol Chem. 2017;292:1637-1647 pubmed 出版商
Sha L, Daitoku H, Araoi S, Kaneko Y, Takahashi Y, Kako K, et al. Asymmetric Arginine Dimethylation Modulates Mitochondrial Energy Metabolism and Homeostasis in Caenorhabditis elegans. Mol Cell Biol. 2017;37: pubmed 出版商
Xu S, Zhang B, Zhu Y, Huang H, Yang W, Huang H, et al. miR-194 functions as a novel modulator of cellular senescence in mouse embryonic fibroblasts. Cell Biol Int. 2017;41:249-257 pubmed 出版商
Olsen S, Wronski A, Castaño Z, Dake B, Malone C, De Raedt T, et al. Loss of RasGAP Tumor Suppressors Underlies the Aggressive Nature of Luminal B Breast Cancers. Cancer Discov. 2017;7:202-217 pubmed 出版商
Zhu Z, Li C, Zeng Y, Ding J, Qu Z, Gu J, et al. PHB Associates with the HIRA Complex to Control an Epigenetic-Metabolic Circuit in Human ESCs. Cell Stem Cell. 2017;20:274-289.e7 pubmed 出版商
Matsunaga K, Taoka M, Isobe T, Izumi T. Rab2a and Rab27a cooperatively regulate the transition from granule maturation to exocytosis through the dual effector Noc2. J Cell Sci. 2017;130:541-550 pubmed 出版商
Kerosuo L, Bronner M. cMyc Regulates the Size of the Premigratory Neural Crest Stem Cell Pool. Cell Rep. 2016;17:2648-2659 pubmed 出版商
Raffeiner P, Schraffl A, Schwarz T, Röck R, Ledolter K, Hartl M, et al. Calcium-dependent binding of Myc to calmodulin. Oncotarget. 2017;8:3327-3343 pubmed 出版商
Huang J, Rajapakse A, Xiong Y, Montani J, Verrey F, Ming X, et al. Genetic Targeting of Arginase-II in Mouse Prevents Renal Oxidative Stress and Inflammation in Diet-Induced Obesity. Front Physiol. 2016;7:560 pubmed
Chen T, Zhou Q, Tang H, Bozkanat M, Yuan J, Raj J, et al. miR-17/20 Controls Prolyl Hydroxylase 2 (PHD2)/Hypoxia-Inducible Factor 1 (HIF1) to Regulate Pulmonary Artery Smooth Muscle Cell Proliferation. J Am Heart Assoc. 2016;5: pubmed
Chmiest D, Sharma N, Zanin N, Viaris de Lesegno C, Shafaq Zadah M, Sibut V, et al. Spatiotemporal control of interferon-induced JAK/STAT signalling and gene transcription by the retromer complex. Nat Commun. 2016;7:13476 pubmed 出版商
Majewski Ł, Maciąg F, Boguszewski P, Wasilewska I, Wiera G, Wójtowicz T, et al. Overexpression of STIM1 in neurons in mouse brain improves contextual learning and impairs long-term depression. Biochim Biophys Acta Mol Cell Res. 2017;1864:1071-1087 pubmed 出版商
Luhtala N, Aslanian A, Yates J, Hunter T. Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner. J Biol Chem. 2017;292:611-628 pubmed 出版商
Yeh Y, Cheng C, Yang S, Tseng C, Chang T, Tsai S, et al. Targeting the VEGF-C/VEGFR3 axis suppresses Slug-mediated cancer metastasis and stemness via inhibition of KRAS/YAP1 signaling. Oncotarget. 2017;8:5603-5618 pubmed 出版商
Shen M, Jiang Y, Guan Z, Cao Y, Sun S, Liu H. FSH protects mouse granulosa cells from oxidative damage by repressing mitophagy. Sci Rep. 2016;6:38090 pubmed 出版商
Galoian K, Luo S, Qureshi A, Patel P, Price R, Morse A, et al. Effect of cytostatic proline rich polypeptide-1 on tumor suppressors of inflammation pathway signaling in chondrosarcoma. Mol Clin Oncol. 2016;5:618-624 pubmed
Yu L, Liang Y, Cao X, Wang X, Gao H, Lin S, et al. Identification of MYST3 as a novel epigenetic activator of ERα frequently amplified in breast cancer. Oncogene. 2017;36:2910-2918 pubmed 出版商
Grabinger T, Bode K, Demgenski J, Seitz C, Delgado M, Kostadinova F, et al. Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-Mediated Destruction of Intestinal Epithelial Cells. Gastroenterology. 2017;152:867-879 pubmed 出版商
Margiotta A, Progida C, Bakke O, Bucci C. Rab7a regulates cell migration through Rac1 and vimentin. Biochim Biophys Acta Mol Cell Res. 2017;1864:367-381 pubmed 出版商
Wang K, Chen C, Tsai S, Shen C. Epigenetic Enhancement of the Post-replicative DNA Mismatch Repair of Mammalian Genomes by a Hemi-mCpG-Np95-Dnmt1 Axis. Sci Rep. 2016;6:37490 pubmed 出版商
McKinney C, Kim M, Chen D, McBride A. Brd4 Activates Early Viral Transcription upon Human Papillomavirus 18 Infection of Primary Keratinocytes. MBio. 2016;7: pubmed 出版商
Choudhury S, Singh A, McLeod T, Blanchette M, Jang B, Badenhorst P, et al. Exon junction complex proteins bind nascent transcripts independently of pre-mRNA splicing in Drosophila melanogaster. elife. 2016;5: pubmed 出版商
Mana G, Clapero F, Panieri E, Panero V, Böttcher R, Tseng H, et al. PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis. Nat Commun. 2016;7:13546 pubmed 出版商
Kaufmann T, Kukolj E, Brachner A, Beltzung E, Bruno M, Kostrhon S, et al. SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation. J Cell Sci. 2016;129:4607-4621 pubmed
Nishina T, Deguchi Y, Miura R, Yamazaki S, Shinkai Y, Kojima Y, et al. Critical Contribution of Nuclear Factor Erythroid 2-related Factor 2 (NRF2) to Electrophile-induced Interleukin-11 Production. J Biol Chem. 2017;292:205-216 pubmed 出版商
Okashita N, Suwa Y, Nishimura O, Sakashita N, Kadota M, Nagamatsu G, et al. PRDM14 Drives OCT3/4 Recruitment via Active Demethylation in the Transition from Primed to Naive Pluripotency. Stem Cell Reports. 2016;7:1072-1086 pubmed 出版商
Vicente Miranda H, Gomes M, Branco Santos J, Breda C, Lázaro D, Lopes L, et al. Glycation potentiates neurodegeneration in models of Huntington's disease. Sci Rep. 2016;6:36798 pubmed 出版商
Zhang Y, Xian Y, Gao L, Elaasar H, Wang Y, Tauhid L, et al. Novel Detection Strategy To Rapidly Evaluate the Efficacy of Antichlamydial Agents. Antimicrob Agents Chemother. 2017;61: pubmed 出版商
Choi H, Cho S, Kim M, Lee H, Moon S, Jang H, et al. SH003 enhances paclitaxel chemosensitivity in MCF-7/PAX breast cancer cells through inhibition of MDR1 activity. Mol Cell Biochem. 2017;426:1-8 pubmed 出版商
Sakata K, Araki K, Nakano H, Nishina T, Komazawa Sakon S, Murai S, et al. Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome. Sci Rep. 2016;6:37200 pubmed 出版商
Kory N, Grond S, Kamat S, Li Z, Krahmer N, Chitraju C, et al. Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism. J Lipid Res. 2017;58:226-235 pubmed 出版商
Vianna M, Poleto D, Gomes P, Valente V, Paçó Larson M. Drosophila ataxin-2 gene encodes two differentially expressed isoforms and its function in larval fat body is crucial for development of peripheral tissues. FEBS Open Bio. 2016;6:1040-1053 pubmed
Mbah N, Overmeyer J, Maltese W. Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based chalcones. Cell Biol Toxicol. 2017;33:263-282 pubmed 出版商
Talbert E, Yang J, Mace T, Farren M, Farris A, Young G, et al. Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities. Mol Cancer Ther. 2017;16:344-356 pubmed 出版商
Lai Y, Su C, Jiang S, Chang Y, Lai A, Huang Y. Deficiency of CPEB2-Confined Choline Acetyltransferase Expression in the Dorsal Motor Nucleus of Vagus Causes Hyperactivated Parasympathetic Signaling-Associated Bronchoconstriction. J Neurosci. 2016;36:12661-12676 pubmed
Natisvili T, Yandim C, Silva R, Emanuelli G, Krueger F, Nageshwaran S, et al. Transcriptional Activation of Pericentromeric Satellite Repeats and Disruption of Centromeric Clustering upon Proteasome Inhibition. PLoS ONE. 2016;11:e0165873 pubmed 出版商
Espigat Georger A, Dyachuk V, Chemin C, Emorine L, Merdes A. Nuclear alignment in myotubes requires centrosome proteins recruited by nesprin-1. J Cell Sci. 2016;129:4227-4237 pubmed
Guirouilh Barbat J, Gelot C, Xie A, Dardillac E, Scully R, Lopez B. 53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks. PLoS Genet. 2016;12:e1006230 pubmed 出版商
Abramowicz I, Carpenter G, Alfieri M, Colnaghi R, Outwin E, Parent P, et al. Oral-facial-digital syndrome type I cells exhibit impaired DNA repair; unanticipated consequences of defective OFD1 outside of the cilia network. Hum Mol Genet. 2017;26:19-32 pubmed 出版商
Liu C, Armstrong C, Lou W, Lombard A, Evans C, Gao A. Inhibition of AKR1C3 Activation Overcomes Resistance to Abiraterone in Advanced Prostate Cancer. Mol Cancer Ther. 2017;16:35-44 pubmed 出版商
Jacob A, Linklater E, Bayless B, Lyons T, Prekeris R. The role and regulation of Rab40b-Tks5 complex during invadopodia formation and cancer cell invasion. J Cell Sci. 2016;129:4341-4353 pubmed
Vranckx L, Demeulemeester J, Debyser Z, Gijsbers R. Towards a Safer, More Randomized Lentiviral Vector Integration Profile Exploring Artificial LEDGF Chimeras. PLoS ONE. 2016;11:e0164167 pubmed 出版商
Kim C, Shin D. Improper hydration induces global gene expression changes associated with renal development in infant mice. Genes Nutr. 2016;11:28 pubmed
Lammirato A, Patsch K, Feiereisen F, Maly K, Nofziger C, Paulmichl M, et al. TIS7 induces transcriptional cascade of methylosome components required for muscle differentiation. BMC Biol. 2016;14:95 pubmed
Wu F, Dai X, Gan W, Wan L, Li M, Mitsiades N, et al. Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation. Cancer Lett. 2017;385:207-214 pubmed 出版商
Tapia Rojas C, Burgos P, Inestrosa N. Inhibition of Wnt signaling induces amyloidogenic processing of amyloid precursor protein and the production and aggregation of Amyloid-? (A?)42 peptides. J Neurochem. 2016;139:1175-1191 pubmed 出版商
Akawi N, Ben Salem S, Hertecant J, John A, Pramathan T, Kizhakkedath P, et al. A homozygous splicing mutation in ELAC2 suggests phenotypic variability including intellectual disability with minimal cardiac involvement. Orphanet J Rare Dis. 2016;11:139 pubmed
Lin Y, Mori E, Kato M, Xiang S, Wu L, Kwon I, et al. Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers. Cell. 2016;167:789-802.e12 pubmed 出版商
Yasuhira S, Shibazaki M, Nishiya M, Maesawa C. Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53. Cell Cycle. 2016;15:3268-3277 pubmed
Valenzuela R, Costa Besada M, Iglesias González J, Perez Costas E, Villar Cheda B, Garrido Gil P, et al. Mitochondrial angiotensin receptors in dopaminergic neurons. Role in cell protection and aging-related vulnerability to neurodegeneration. Cell Death Dis. 2016;7:e2427 pubmed 出版商
Ballantyne L, Sin Y, Al Dirbashi O, Li X, Hurlbut D, Funk C. Liver-specific knockout of arginase-1 leads to a profound phenotype similar to inducible whole body arginase-1 deficiency. Mol Genet Metab Rep. 2016;9:54-60 pubmed
Luo W, Lieu Z, Manser E, Bershadsky A, Sheetz M. Formin DAAM1 Organizes Actin Filaments in the Cytoplasmic Nodal Actin Network. PLoS ONE. 2016;11:e0163915 pubmed 出版商
Wang Y, Hsu J, Kang Y, Wei Y, Lee P, Chang S, et al. Oncogenic Functions of Gli1 in Pancreatic Adenocarcinoma Are Supported by Its PRMT1-Mediated Methylation. Cancer Res. 2016;76:7049-7058 pubmed
Kratz A, Richter K, Schlosser Y, Schmitt M, Shumilov A, Delecluse H, et al. Fbxo28 promotes mitotic progression and regulates topoisomerase II?-dependent DNA decatenation. Cell Cycle. 2016;15:3419-3431 pubmed 出版商
Perrody E, Abrami L, Feldman M, Kunz B, Urbé S, van der Goot F. Ubiquitin-dependent folding of the Wnt signaling coreceptor LRP6. elife. 2016;5: pubmed 出版商
Coccia A, Mosca L, Puca R, Mangino G, Rossi A, Lendaro E. Extra-virgin olive oil phenols block cell cycle progression and modulate chemotherapeutic toxicity in bladder cancer cells. Oncol Rep. 2016;36:3095-3104 pubmed 出版商
Qi D, Cobrinik D. MDM2 but not MDM4 promotes retinoblastoma cell proliferation through p53-independent regulation of MYCN translation. Oncogene. 2017;36:1760-1769 pubmed 出版商
Reynaud C, Ferreras L, Di Mauro P, Kan C, Croset M, Bonnelye E, et al. Lysyl Oxidase Is a Strong Determinant of Tumor Cell Colonization in Bone. Cancer Res. 2017;77:268-278 pubmed 出版商
O Sullivan S, Tay M, Lin J, Bava U, Callon K, Cornish J, et al. Tyrosine Kinase Inhibitors Regulate OPG through Inhibition of PDGFR?. PLoS ONE. 2016;11:e0164727 pubmed 出版商
Rajgor D, Hanley J, Shanahan C. Identification of novel nesprin-1 binding partners and cytoplasmic matrin-3 in processing bodies. Mol Biol Cell. 2016;27:3894-3902 pubmed
Yi Lo J, O Connor A, Andrews Z, Lo C, Tiganis T, Watt M, et al. RABL2 Is Required for Hepatic Fatty Acid Homeostasis and Its Dysfunction Leads to Steatosis and a Diabetes-Like State. Endocrinology. 2016;157:4732-4743 pubmed
Losada A, Mu oz Alonso M, Garc a C, S nchez Murcia P, Mart nez Leal J, Dom nguez J, et al. Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin. Sci Rep. 2016;6:35100 pubmed 出版商
Sannino G, Armbruster N, Bodenhöfer M, Haerle U, Behrens D, Buchholz M, et al. Role of BCL9L in transforming growth factor-β (TGF-β)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer. Oncotarget. 2016;7:73725-73738 pubmed 出版商
Beauvais G, Bode N, Watson J, Wen H, Glenn K, Kawano H, et al. Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis. J Neurosci. 2016;36:10245-10256 pubmed
Shintaku J, Peterson J, Talbert E, Gu J, Ladner K, Williams D, et al. MyoD Regulates Skeletal Muscle Oxidative Metabolism Cooperatively with Alternative NF-?B. Cell Rep. 2016;17:514-526 pubmed 出版商
Bandiera E, Todeschini P, Romani C, Zanotti L, Erba E, Colmegna B, et al. The HIV-protease inhibitor saquinavir reduces proliferation, invasion and clonogenicity in cervical cancer cell lines. Oncol Lett. 2016;12:2493-2500 pubmed
Chang T, Wang S, Chen L, Shih Y, Chang L, Liu S, et al. Regulation of the Abundance of Kaposi's Sarcoma-Associated Herpesvirus ORF50 Protein by Oncoprotein MDM2. PLoS Pathog. 2016;12:e1005918 pubmed 出版商
Landry Voyer A, Bilodeau S, Bergeron D, Dionne K, Port S, Rouleau C, et al. Human PDCD2L Is an Export Substrate of CRM1 That Associates with 40S Ribosomal Subunit Precursors. Mol Cell Biol. 2016;36:3019-3032 pubmed
Jin Y, Han Y, Khadka D, Zhao C, Lee K, Cho W. Discovery of Isoquinolinoquinazolinones as a Novel Class of Potent PPAR? Antagonists with Anti-adipogenic Effects. Sci Rep. 2016;6:34661 pubmed 出版商
Matijasevic Z, Krzywicka Racka A, Sluder G, Gallant J, Jones S. The Zn-finger domain of MdmX suppresses cancer progression by promoting genome stability in p53-mutant cells. Oncogenesis. 2016;5:e262 pubmed 出版商
Githaka J, Vega A, Baird M, Davidson M, Jaqaman K, Touret N. Ligand-induced growth and compaction of CD36 nanoclusters enriched in Fyn induces Fyn signaling. J Cell Sci. 2016;129:4175-4189 pubmed
Zhang Y, Wang X, Matakatsu H, Fehon R, Blair S. The novel SH3 domain protein Dlish/CG10933 mediates fat signaling in Drosophila by binding and regulating Dachs. elife. 2016;5: pubmed 出版商
Li J, Chauve L, Phelps G, Brielmann R, Morimoto R. E2F coregulates an essential HSF developmental program that is distinct from the heat-shock response. Genes Dev. 2016;30:2062-2075 pubmed
Yadav S, Magre I, Singh A, Khuperkar D, Joseph J. Regulation of aPKC activity by Nup358 dependent SUMO modification. Sci Rep. 2016;6:34100 pubmed 出版商
Boo H, Min H, Jang H, Yun H, Smith J, Jin Q, et al. The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells. Nat Commun. 2016;7:12961 pubmed 出版商
Flex E, Niceta M, Cecchetti S, Thiffault I, Au M, Capuano A, et al. Biallelic Mutations in TBCD, Encoding the Tubulin Folding Cofactor D, Perturb Microtubule Dynamics and Cause Early-Onset Encephalopathy. Am J Hum Genet. 2016;99:962-973 pubmed 出版商
Anantharaman A, Jadaliha M, Tripathi V, Nakagawa S, Hirose T, Jantsch M, et al. Paraspeckles modulate the intranuclear distribution of paraspeckle-associated Ctn RNA. Sci Rep. 2016;6:34043 pubmed 出版商
Guida N, Laudati G, Mascolo L, Cuomo O, Anzilotti S, Sirabella R, et al. MC1568 Inhibits Thimerosal-Induced Apoptotic Cell Death by Preventing HDAC4 Up-Regulation in Neuronal Cells and in Rat Prefrontal Cortex. Toxicol Sci. 2016;154:227-240 pubmed
Ma H, Song T, Wang T, Wang S. Influence of Human p53 on Plant Development. PLoS ONE. 2016;11:e0162840 pubmed 出版商
Jin Y, Zhou J, Xu F, Jin B, Cui L, Wang Y, et al. Targeting methyltransferase PRMT5 eliminates leukemia stem cells in chronic myelogenous leukemia. J Clin Invest. 2016;126:3961-3980 pubmed 出版商
CONTRERAS C, González García I, Seoane Collazo P, Martínez Sánchez N, Liñares Pose L, Rial Pensado E, et al. Reduction of Hypothalamic Endoplasmic Reticulum Stress Activates Browning of White Fat and Ameliorates Obesity. Diabetes. 2017;66:87-99 pubmed 出版商
Gross S, Devraj K, Feng Y, Macas J, Liebner S, Wieland T. Nucleoside diphosphate kinase B regulates angiogenic responses in the endothelium via caveolae formation and c-Src-mediated caveolin-1 phosphorylation. J Cereb Blood Flow Metab. 2017;37:2471-2484 pubmed 出版商
Haller M, Khalid S, Kremser L, Fresser F, Furlan T, Hermann M, et al. Novel Insights into the PKC?-dependent Regulation of the Oxidoreductase p66Shc. J Biol Chem. 2016;291:23557-23568 pubmed
Swart P, Currin C, Russell V, Dimatelis J. Early ethanol exposure and vinpocetine treatment alter learning- and memory-related proteins in the rat hippocampus and prefrontal cortex. J Neurosci Res. 2017;95:1204-1215 pubmed 出版商
Mauri M, Kirchner M, Aharoni R, Ciolli Mattioli C, van den Bruck D, Gutkovitch N, et al. Conservation of miRNA-mediated silencing mechanisms across 600 million years of animal evolution. Nucleic Acids Res. 2017;45:938-950 pubmed 出版商
Fernandes M, Melo S, Velho S, Carneiro P, Carneiro F, Seruca R. Specific inhibition of p110α subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancers. Oncotarget. 2016;7:68546-68558 pubmed 出版商
Li D, Li K, Chen G, Xia J, Yang T, Cai P, et al. S100B suppresses the differentiation of C3H/10T1/2 murine embryonic mesenchymal cells into osteoblasts. Mol Med Rep. 2016;14:3878-86 pubmed 出版商
Gastebois C, Chanon S, Rome S, Durand C, Pelascini E, Jalabert A, et al. Transition from physical activity to inactivity increases skeletal muscle miR-148b content and triggers insulin resistance. Physiol Rep. 2016;4: pubmed 出版商
Richard G, Dalle S, Monet M, Ligier M, Boespflug A, Pommier R, et al. ZEB1-mediated melanoma cell plasticity enhances resistance to MAPK inhibitors. EMBO Mol Med. 2016;8:1143-1161 pubmed 出版商
Chen W, Hill H, Christie A, Kim M, Holloman E, Pavía Jiménez A, et al. Targeting renal cell carcinoma with a HIF-2 antagonist. Nature. 2016;539:112-117 pubmed 出版商
Su C, Chang T, Hsu H, Lai H, Li J, Lyu Y, et al. A novel application of E1A in combination therapy with EGFR-TKI treatment in breast cancer. Oncotarget. 2016;7:63924-63936 pubmed 出版商
Gai M, Bianchi F, Vagnoni C, Vernì F, Bonaccorsi S, Pasquero S, et al. ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules. EMBO Rep. 2016;17:1396-1409 pubmed
Oza J, Ganguly B, Kulkarni A, Ginjala V, Yao M, Ganesan S. A Novel Role of Chromodomain Protein CBX8 in DNA Damage Response. J Biol Chem. 2016;291:22881-22893 pubmed
Yamada Y, Sato F. Tyrosine phosphorylation and protein degradation control the transcriptional activity of WRKY involved in benzylisoquinoline alkaloid biosynthesis. Sci Rep. 2016;6:31988 pubmed 出版商
Bonsignore L, Passelli K, Pelzer C, Perroud M, Konrad A, Thurau M, et al. A role for MALT1 activity in Kaposi's sarcoma-associated herpes virus latency and growth of primary effusion lymphoma. Leukemia. 2017;31:614-624 pubmed 出版商
Xiang M, Kim H, Ho V, Walker S, Bar Natan M, Anahtar M, et al. Gene expression-based discovery of atovaquone as a STAT3 inhibitor and anticancer agent. Blood. 2016;128:1845-1853 pubmed 出版商
Kockel L, Huq L, Ayyar A, Herold E, MacAlpine E, Logan M, et al. A Drosophila LexA Enhancer-Trap Resource for Developmental Biology and Neuroendocrine Research. G3 (Bethesda). 2016;6:3017-3026 pubmed 出版商
Yao C, Chow J, Yang C, Kuo H, Chang C, Lee H, et al. Chinese Herbal Mixture, Tien-Hsien Liquid, Induces G2/M Cycle Arrest and Radiosensitivity in MCF-7 Human Breast Cancer Cells through Mechanisms Involving DNMT1 and Rad51 Downregulation. Evid Based Complement Alternat Med. 2016;2016:3251046 pubmed 出版商
Di Cecilia S, Zhang F, Sancho A, Li S, Aguilo F, Sun Y, et al. RBM5-AS1 Is Critical for Self-Renewal of Colon Cancer Stem-like Cells. Cancer Res. 2016;76:5615-5627 pubmed
Pfister J, D Mello S. Regulation of Neuronal Survival by Nucleophosmin 1 (NPM1) Is Dependent on Its Expression Level, Subcellular Localization, and Oligomerization Status. J Biol Chem. 2016;291:20787-97 pubmed 出版商
Geekiyanage H, Galanis E. MiR-31 and miR-128 regulates poliovirus receptor-related 4 mediated measles virus infectivity in tumors. Mol Oncol. 2016;10:1387-1403 pubmed 出版商
Ota S, Zhou Z, Romero M, Yang G, Hurlin P. HDAC6 deficiency or inhibition blocks FGFR3 accumulation and improves bone growth in a model of achondroplasia. Hum Mol Genet. 2016;25:4227-4243 pubmed 出版商
Hendrick J, Franz Wachtel M, Moeller Y, Schmid S, Macek B, Olayioye M. The polarity protein Scribble positions DLC3 at adherens junctions to regulate Rho signaling. J Cell Sci. 2016;129:3583-3596 pubmed
Shin J, Jeon H, Park J, Chang M. Epigallocatechin-3-gallate prevents oxidative stress-induced cellular senescence in human mesenchymal stem cells via Nrf2. Int J Mol Med. 2016;38:1075-82 pubmed 出版商
McAllaster M, Sinclair Davis A, Hilton N, de Graffenried C. A unified approach towards Trypanosoma brucei functional genomics using Gibson assembly. Mol Biochem Parasitol. 2016;210:13-21 pubmed 出版商
Ahsan S, Ge Y, Tainsky M. Combinatorial therapeutic targeting of BMP2 and MEK-ERK pathways in NF1-associated malignant peripheral nerve sheath tumors. Oncotarget. 2016;7:57171-57185 pubmed 出版商
Nakashima H, Okimura C, Iwadate Y. The molecular dynamics of crawling migration in microtubule-disrupted keratocytes. Biophys Physicobiol. 2015;12:21-9 pubmed 出版商
Rocha D, Marques A, Andrade C, Guyot R, Chaluvadi S, Pedrosa Harand A, et al. Developmental programmed cell death during asymmetric microsporogenesis in holocentric species of Rhynchospora (Cyperaceae). J Exp Bot. 2016;67:5391-5401 pubmed
Sanchez M, Tran K, Valli J, Hobbs S, Johnson E, Gluenz E, et al. KHARON Is an Essential Cytoskeletal Protein Involved in the Trafficking of Flagellar Membrane Proteins and Cell Division in African Trypanosomes. J Biol Chem. 2016;291:19760-73 pubmed 出版商
Marques A, Schubert V, Houben A, Pedrosa Harand A. Restructuring of Holocentric Centromeres During Meiosis in the Plant Rhynchospora pubera. Genetics. 2016;204:555-568 pubmed
Velinder M, Singer J, Bareyan D, Meznarich J, Tracy C, Fulcher J, et al. GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1. Biochem J. 2016;473:3355-69 pubmed 出版商
Fante T, Simino L, Reginato A, Payolla T, Vitoréli D, Souza M, et al. Diet-Induced Maternal Obesity Alters Insulin Signalling in Male Mice Offspring Rechallenged with a High-Fat Diet in Adulthood. PLoS ONE. 2016;11:e0160184 pubmed 出版商
Lim Y, Bacchiocchi A, Qiu J, Straub R, Bruckner A, Bercovitch L, et al. GNA14 Somatic Mutation Causes Congenital and Sporadic Vascular Tumors by MAPK Activation. Am J Hum Genet. 2016;99:443-50 pubmed 出版商
Dai L, Chen K, Youngren B, Kulina J, Yang A, Guo Z, et al. Cytoplasmic Drosha activity generated by alternative splicing. Nucleic Acids Res. 2016;44:10454-10466 pubmed
Brinkmann B, Steinbacher T, Hartmann C, Kummer D, Pajonczyk D, Mirzapourshafiyi F, et al. VE-cadherin interacts with cell polarity protein Pals1 to regulate vascular lumen formation. Mol Biol Cell. 2016;27:2811-21 pubmed 出版商
Zhang P, Wang S, Wang S, Qiao J, Zhang L, Zhang Z, et al. Dual function of partitioning-defective 3 in the regulation of YAP phosphorylation and activation. Cell Discov. 2016;2:16021 pubmed 出版商
Aversa Z, Pin F, Lucia S, Penna F, Verzaro R, Fazi M, et al. Autophagy is induced in the skeletal muscle of cachectic cancer patients. Sci Rep. 2016;6:30340 pubmed 出版商
Terao M, Barzago M, Kurosaki M, Fratelli M, Bolis M, Borsotti A, et al. Mouse aldehyde-oxidase-4 controls diurnal rhythms, fat deposition and locomotor activity. Sci Rep. 2016;6:30343 pubmed 出版商
Moutel S, Bery N, Bernard V, Keller L, Lemesre E, de Marco A, et al. NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies. elife. 2016;5: pubmed 出版商
Kallens V, Tobar N, Molina J, Bidegain A, Smith P, Porras O, et al. Glucose Promotes a Pro-Oxidant and Pro-Inflammatory Stromal Microenvironment Which Favors Motile Properties in Breast Tumor Cells. J Cell Biochem. 2017;118:994-1002 pubmed 出版商
Mohibi S, Srivastava S, Bele A, Mirza S, Band H, Band V. Acetylation of Mammalian ADA3 Is Required for Its Functional Roles in Histone Acetylation and Cell Proliferation. Mol Cell Biol. 2016;36:2487-502 pubmed 出版商
de Queiroz R, Madan R, Chien J, Dias W, Slawson C. Changes in O-Linked N-Acetylglucosamine (O-GlcNAc) Homeostasis Activate the p53 Pathway in Ovarian Cancer Cells. J Biol Chem. 2016;291:18897-914 pubmed 出版商
Liu X, Zhang Z, Ruan J, Pan Y, Magupalli V, Wu H, et al. Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores. Nature. 2016;535:153-8 pubmed 出版商
Martin Sanchez D, Ruiz Andrés O, Poveda J, Carrasco S, Cannata Ortiz P, Sanchez Niño M, et al. Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid-Induced AKI. J Am Soc Nephrol. 2017;28:218-229 pubmed 出版商
Fujiwara M, Kato S, Niwa Y, Suzuki T, Tsuchiya M, Sasazawa Y, et al. C-mannosylation of R-spondin3 regulates its secretion and activity of Wnt/?-catenin signaling in cells. FEBS Lett. 2016;590:2639-49 pubmed 出版商
Rausell A, Muñoz M, Martinez R, Roger T, Telenti A, Ciuffi A. Innate immune defects in HIV permissive cell lines. Retrovirology. 2016;13:43 pubmed 出版商
Hahm E, Singh K, Singh S. c-Myc is a novel target of cell cycle arrest by honokiol in prostate cancer cells. Cell Cycle. 2016;15:2309-20 pubmed 出版商
Kim J, Kang H, Park J, Kim W, Yoo J, Lee N, et al. PIF1-Interacting Transcription Factors and Their Binding Sequence Elements Determine the in Vivo Targeting Sites of PIF1. Plant Cell. 2016;28:1388-405 pubmed 出版商
Ormeño F, Barrientos C, Ramirez S, Ponce I, Valenzuela L, Sepúlveda S, et al. Expression and the Peculiar Enzymatic Behavior of the Trypanosoma cruzi NTH1 DNA Glycosylase. PLoS ONE. 2016;11:e0157270 pubmed 出版商
Norman M, Vuilleumier R, Springhorn A, Gawlik J, Pyrowolakis G. Pentagone internalises glypicans to fine-tune multiple signalling pathways. elife. 2016;5: pubmed 出版商
Li X, Zhong Y, Lu J, Axcrona K, Eide L, Syljuåsen R, et al. MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features. Oncotarget. 2016;7:40297-40313 pubmed 出版商
Wardman J, Gomes I, Bobeck E, Stockert J, Kapoor A, Bisignano P, et al. Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake. Sci Signal. 2016;9:ra55 pubmed 出版商
Ferraro E, Pin F, Gorini S, Pontecorvo L, Ferri A, Mollace V, et al. Improvement of skeletal muscle performance in ageing by the metabolic modulator Trimetazidine. J Cachexia Sarcopenia Muscle. 2016;7:449-57 pubmed 出版商
Penna F, Bonetto A, Aversa Z, Minero V, Rossi Fanelli F, Costelli P, et al. Effect of the specific proteasome inhibitor bortezomib on cancer-related muscle wasting. J Cachexia Sarcopenia Muscle. 2016;7:345-54 pubmed 出版商
Colombo S, Cardani S, Maroli A, Vitiello A, Soffientini P, Crespi A, et al. Tail-anchored Protein Insertion in Mammals: FUNCTION AND RECIPROCAL INTERACTIONS OF THE TWO SUBUNITS OF THE TRC40 RECEPTOR. J Biol Chem. 2016;291:15292-306 pubmed 出版商
Harris K, Akbergenova Y, Cho R, Baas Thomas M, Littleton J. Shank Modulates Postsynaptic Wnt Signaling to Regulate Synaptic Development. J Neurosci. 2016;36:5820-32 pubmed 出版商
Gale M, Sayegh J, Cao J, Norcia M, Gareiss P, Hoyer D, et al. Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance. Oncotarget. 2016;7:39931-39944 pubmed 出版商
Lobo M, Amaral M, Zaccolo M, Farinha C. EPAC1 activation by cAMP stabilizes CFTR at the membrane by promoting its interaction with NHERF1. J Cell Sci. 2016;129:2599-612 pubmed 出版商
Koskela A, Reinisalo M, Petrovski G, Sinha D, Olmiere C, Karjalainen R, et al. Nutraceutical with Resveratrol and Omega-3 Fatty Acids Induces Autophagy in ARPE-19 Cells. Nutrients. 2016;8: pubmed 出版商
Al Massadi O, Porteiro B, Kuhlow D, Köhler M, Gonzalez Rellan M, Garcia Lavandeira M, et al. Pharmacological and Genetic Manipulation of p53 in Brown Fat at Adult But Not Embryonic Stages Regulates Thermogenesis and Body Weight in Male Mice. Endocrinology. 2016;157:2735-49 pubmed 出版商
Gómez SanMiguel A, Villanúa M, Martín A, López Calderón A. D-TRP(8)-γMSH Prevents the Effects of Endotoxin in Rat Skeletal Muscle Cells through TNFα/NF-KB Signalling Pathway. PLoS ONE. 2016;11:e0155645 pubmed 出版商
Markert S, Britz S, Proppert S, Lang M, Witvliet D, Mulcahy B, et al. Filling the gap: adding super-resolution to array tomography for correlated ultrastructural and molecular identification of electrical synapses at the C. elegans connectome. Neurophotonics. 2016;3:041802 pubmed 出版商
Materne P, Vazquez E, Sanchez M, Yague Sanz C, Anandhakumar J, Migeot V, et al. Histone H2B ubiquitylation represses gametogenesis by opposing RSC-dependent chromatin remodeling at the ste11 master regulator locus. elife. 2016;5: pubmed 出版商
Reid D, Tay A, Sundaram J, Lee I, Chen Q, George S, et al. Complementary Roles of GADD34- and CReP-Containing Eukaryotic Initiation Factor 2? Phosphatases during the Unfolded Protein Response. Mol Cell Biol. 2016;36:1868-80 pubmed 出版商
Waku T, Nakajima Y, Yokoyama W, Nomura N, Kako K, Kobayashi A, et al. NML-mediated rRNA base methylation links ribosomal subunit formation to cell proliferation in a p53-dependent manner. J Cell Sci. 2016;129:2382-93 pubmed 出版商
Nixon B, Anderson A, Smith N, McLeod R, Johnston S. The Australian saltwater crocodile (Crocodylus porosus) provides evidence that the capacitation of spermatozoa may extend beyond the mammalian lineage. Proc Biol Sci. 2016;283: pubmed 出版商
Ma J, Mi C, Wang K, Lee J, Jin X. Zinc finger protein 91 (ZFP91) activates HIF-1? via NF-?B/p65 to promote proliferation and tumorigenesis of colon cancer. Oncotarget. 2016;7:36551-36562 pubmed 出版商
Mansouri M, Bellón Echeverría I, Rizk A, Ehsaei Z, Cianciolo Cosentino C, Silva C, et al. Highly efficient baculovirus-mediated multigene delivery in primary cells. Nat Commun. 2016;7:11529 pubmed 出版商
Wilhelm T, Ragu S, Magdalou I, Machon C, Dardillac E, Técher H, et al. Slow Replication Fork Velocity of Homologous Recombination-Defective Cells Results from Endogenous Oxidative Stress. PLoS Genet. 2016;12:e1006007 pubmed 出版商
Tsuchiya M, Niwa Y, Simizu S. N-glycosylation of R-spondin1 at Asn137 negatively regulates its secretion and Wnt/?-catenin signaling-enhancing activity. Oncol Lett. 2016;11:3279-3286 pubmed
Choi H, Kim M, Choi Y, Shin Y, Cho S, Ko S. Rhus verniciflua Stokes (RVS) and butein induce apoptosis of paclitaxel-resistant SKOV-3/PAX ovarian cancer cells through inhibition of AKT phosphorylation. BMC Complement Altern Med. 2016;16:122 pubmed 出版商
Absalon S, Robbins J, Dvorin J. An essential malaria protein defines the architecture of blood-stage and transmission-stage parasites. Nat Commun. 2016;7:11449 pubmed 出版商
Gomes I, Bobeck E, Margolis E, Gupta A, Sierra S, Fakira A, et al. Identification of GPR83 as the receptor for the neuroendocrine peptide PEN. Sci Signal. 2016;9:ra43 pubmed 出版商
Sundvold H, Sundvold Gjerstad V, Malerød Fjeld H, Haglund K, Stenmark H, Malerød L. Arv1 promotes cell division by recruiting IQGAP1 and myosin to the cleavage furrow. Cell Cycle. 2016;15:628-43 pubmed 出版商
Tang A, Shi P, Song A, Zou D, Zhou Y, Gu P, et al. PP2A regulates kinetochore-microtubule attachment during meiosis I in oocyte. Cell Cycle. 2016;15:1450-61 pubmed 出版商
Chapdelaine P, Gerard C, Sanchez N, Cherif K, Rousseau J, Ouellet D, et al. Development of an AAV9 coding for a 3XFLAG-TALEfrat#8-VP64 able to increase in vivo the human frataxin in YG8R mice. Gene Ther. 2016;23:606-14 pubmed 出版商
Byrne A, Roche S, Ruiz Lopez A, Jackson A, Cotter T. The synthetic progestin norgestrel acts to increase LIF levels in the rd10 mouse model of retinitis pigmentosa. Mol Vis. 2016;22:264-74 pubmed
Pourchet A, Fuhrmann S, Pilones K, Demaria S, Frey A, Mulvey M, et al. CD8(+) T-cell Immune Evasion Enables Oncolytic Virus Immunotherapy. EBioMedicine. 2016;5:59-67 pubmed 出版商
Lanza C, Tan E, Zhang Z, Machacek M, Brinker A, Azuma M, et al. Reduced O-GlcNAcase expression promotes mitotic errors and spindle defects. Cell Cycle. 2016;15:1363-75 pubmed 出版商
Merino D, Villar A, Garcia R, Tramullas M, Ruiz L, Ribas C, et al. BMP-7 attenuates left ventricular remodelling under pressure overload and facilitates reverse remodelling and functional recovery. Cardiovasc Res. 2016;110:331-45 pubmed 出版商
Dowd G, Bhalla M, Kean B, Thomas R, Ireton K. Role of Host Type IA Phosphoinositide 3-Kinase Pathway Components in Invasin-Mediated Internalization of Yersinia enterocolitica. Infect Immun. 2016;84:1826-1841 pubmed 出版商
Barbelanne M, Chiu A, Qian J, Tsang W. Opposing post-translational modifications regulate Cep76 function to suppress centriole amplification. Oncogene. 2016;35:5377-5387 pubmed 出版商
Buck S, Maqani N, Matecic M, Hontz R, Fine R, Li M, et al. RNA Polymerase I and Fob1 contributions to transcriptional silencing at the yeast rDNA locus. Nucleic Acids Res. 2016;44:6173-84 pubmed 出版商
Liu C, Armstrong C, Zhu Y, Lou W, Gao A. Niclosamide enhances abiraterone treatment via inhibition of androgen receptor variants in castration resistant prostate cancer. Oncotarget. 2016;7:32210-20 pubmed 出版商
Hoban A, Stilling R, Ryan F, Shanahan F, Dinan T, Claesson M, et al. Regulation of prefrontal cortex myelination by the microbiota. Transl Psychiatry. 2016;6:e774 pubmed 出版商
Kasai S, Arakawa N, Okubo A, Shigeeda W, Yasuhira S, Masuda T, et al. NAD(P)H:Quinone Oxidoreductase-1 Expression Sensitizes Malignant Melanoma Cells to the HSP90 Inhibitor 17-AAG. PLoS ONE. 2016;11:e0153181 pubmed 出版商
Murata K, Ishida J, Ishimaru T, Mizukami H, Hamada J, Saito C, et al. Lactation Is a Risk Factor of Postpartum Heart Failure in Mice with Cardiomyocyte-specific Apelin Receptor (APJ) Overexpression. J Biol Chem. 2016;291:11241-51 pubmed 出版商
Belichenko P, Madani R, Rey Bellet L, Pihlgren M, Becker A, Plassard A, et al. An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome. PLoS ONE. 2016;11:e0152471 pubmed 出版商
Skalecka A, Liszewska E, Bilinski R, Gkogkas C, Khoutorsky A, Malik A, et al. mTOR kinase is needed for the development and stabilization of dendritic arbors in newly born olfactory bulb neurons. Dev Neurobiol. 2016;76:1308-1327 pubmed 出版商
Zhang Y, Gendron T, Grima J, Sasaguri H, Jansen West K, Xu Y, et al. C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins. Nat Neurosci. 2016;19:668-677 pubmed 出版商
Bezbradica J, Coll R, Schroder K. Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signals. Cell Mol Immunol. 2017;14:118-126 pubmed 出版商
Blazejczyk M, Macias M, Korostynski M, Firkowska M, Piechota M, Skalecka A, et al. Kainic Acid Induces mTORC1-Dependent Expression of Elmo1 in Hippocampal Neurons. Mol Neurobiol. 2017;54:2562-2578 pubmed 出版商
Yang L, Wang H, Wang Y, He Z, Chen H, Liang S, et al. Prostate tumor overexpressed-1, in conjunction with human papillomavirus status, predicts outcome in early-stage human laryngeal squamous cell carcinoma. Oncotarget. 2016;7:31878-91 pubmed 出版商
Leocadio D, Mitchell A, Winder S. ?-Secretase Dependent Nuclear Targeting of Dystroglycan. J Cell Biochem. 2016;117:2149-57 pubmed 出版商
Takahashi Y, Tsotakos N, Liu Y, Young M, Serfass J, Tang Z, et al. The Bif-1-Dynamin 2 membrane fission machinery regulates Atg9-containing vesicle generation at the Rab11-positive reservoirs. Oncotarget. 2016;7:20855-68 pubmed 出版商
Grampa V, Delous M, Zaidan M, Odye G, Thomas S, Elkhartoufi N, et al. Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation. PLoS Genet. 2016;12:e1005894 pubmed 出版商
Choi H, Lee K, Kim M, Lee K, Shin Y, Cho S, et al. DSGOST inhibits tumor growth by blocking VEGF/VEGFR2-activated angiogenesis. Oncotarget. 2016;7:21775-85 pubmed 出版商
Eno C, SOLANKI B, Pelegri F. aura (mid1ip1l) regulates the cytoskeleton at the zebrafish egg-to-embryo transition. Development. 2016;143:1585-99 pubmed 出版商
Wang G, Liu X, Gaertig M, Li S, Li X. Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis. Proc Natl Acad Sci U S A. 2016;113:3359-64 pubmed 出版商
Kilinc S, Savarino A, Coleman J, Schwob J, Lane R. Lysine-specific demethylase-1 (LSD1) is compartmentalized at nuclear chromocenters in early post-mitotic cells of the olfactory sensory neuronal lineage. Mol Cell Neurosci. 2016;74:58-70 pubmed 出版商
de la Ballina L, Cano Crespo S, González Muñoz E, Bial S, Estrach S, Cailleteau L, et al. Amino Acid Transport Associated to Cluster of Differentiation 98 Heavy Chain (CD98hc) Is at the Cross-road of Oxidative Stress and Amino Acid Availability. J Biol Chem. 2016;291:9700-11 pubmed 出版商
Janssens V, Zwaenepoel K, Rosse C, Petit M, Goris J, Parker P. PP2A binds to the LIM domains of lipoma-preferred partner through its PR130/B″ subunit to regulate cell adhesion and migration. J Cell Sci. 2016;129:1605-18 pubmed 出版商
Takemata N, Oda A, Yamada T, Galipon J, Miyoshi T, Suzuki Y, et al. Local potentiation of stress-responsive genes by upstream noncoding transcription. Nucleic Acids Res. 2016;44:5174-89 pubmed 出版商
Woo S, Choi Y, Kim A, Yun Y, Shin Y, Cho S, et al. Sip-jeon-dea-bo-tang, a traditional herbal medicine, ameliorates cisplatin-induced anorexia via the activation of JAK1/STAT3-mediated leptin and IL-6 production in the fat tissue of mice. Mol Med Rep. 2016;13:2967-72 pubmed 出版商
Dubon M, Park K. The mechanisms of substance P-mediated migration of bone marrow-derived mesenchymal stem cell-like ST2 cells. Int J Mol Med. 2016;37:1105-11 pubmed 出版商
Takekawa Y, Sato Y, Yamaki Y, Imai M, Noto K, Sumi M, et al. An Approach to Improve Intestinal Absorption of Poorly Absorbed Water-Insoluble Components via Niemann-Pick C1-Like 1. Biol Pharm Bull. 2016;39:301-7 pubmed 出版商
Pema M, Drusian L, Chiaravalli M, Castelli M, Yao Q, Ricciardi S, et al. mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex. Nat Commun. 2016;7:10786 pubmed 出版商
Anda S, Rothe C, Boye E, Grallert B. Consequences of abnormal CDK activity in S phase. Cell Cycle. 2016;15:963-73 pubmed 出版商
Ristić G, Tsou W, Guzi E, Kanack A, SCAGLIONE K, Todi S. USP5 Is Dispensable for Monoubiquitin Maintenance in Drosophila. J Biol Chem. 2016;291:9161-72 pubmed 出版商
Kumar A, Zhang J, Tallaksen Greene S, Crowley M, Crossman D, Morton A, et al. Allelic series of Huntington's disease knock-in mice reveals expression discorrelates. Hum Mol Genet. 2016;25:1619-36 pubmed 出版商
Arora G, Tran S, Rizzo N, Jain A, Welte M. Temporal control of bidirectional lipid-droplet motion in Drosophila depends on the ratio of kinesin-1 and its co-factor Halo. J Cell Sci. 2016;129:1416-28 pubmed 出版商
Heinnickel M, Kim R, Wittkopp T, Yang W, Walters K, Herbert S, et al. Tetratricopeptide repeat protein protects photosystem I from oxidative disruption during assembly. Proc Natl Acad Sci U S A. 2016;113:2774-9 pubmed 出版商
Chu T, MacNeil D, Autexier C. Multiple Mechanisms Contribute to the Cell Growth Defects Imparted by Human Telomerase Insertion in Fingers Domain Mutations Associated with Premature Aging Diseases. J Biol Chem. 2016;291:8374-86 pubmed 出版商
Mei Y, Monteiro P, Zhou Y, Kim J, Gao X, Fu Z, et al. Adult restoration of Shank3 expression rescues selective autistic-like phenotypes. Nature. 2016;530:481-4 pubmed 出版商
Bhargava A, Anant M, Mack H. Registered report: Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF. elife. 2016;5: pubmed 出版商
Kim M, Sandford E, Gatica D, Qiu Y, Liu X, Zheng Y, et al. Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay. elife. 2016;5: pubmed 出版商
Schafer J, McRae R, Manning E, Lapierre L, Goldenring J. Rab11-FIP1A regulates early trafficking into the recycling endosomes. Exp Cell Res. 2016;340:259-73 pubmed 出版商
Leng G, Song K. Direct interaction of Ste11 and Mkk1/2 through Nst1 integrates high-osmolarity glycerol and pheromone pathways to the cell wall integrity MAPK pathway. FEBS Lett. 2016;590:148-60 pubmed 出版商
Fu X, Gao X, Ge L, Cui X, Su C, Yang W, et al. Malonate induces the assembly of cytoplasmic stress granules. FEBS Lett. 2016;590:22-33 pubmed 出版商
Ávila Arroyo S, Nuñez G, García Fernández L, Galmarini C. Synergistic Effect of Trabectedin and Olaparib Combination Regimen in Breast Cancer Cell Lines. J Breast Cancer. 2015;18:329-38 pubmed 出版商
Niwa Y, Suzuki T, Dohmae N, Simizu S. Identification of DPY19L3 as the C-mannosyltransferase of R-spondin1 in human cells. Mol Biol Cell. 2016;27:744-56 pubmed 出版商
Kalebic N, Taverna E, Tavano S, Wong F, Suchold D, Winkler S, et al. CRISPR/Cas9-induced disruption of gene expression in mouse embryonic brain and single neural stem cells in vivo. EMBO Rep. 2016;17:338-48 pubmed 出版商
Ho N, Morrison J, Silva A, Coomber B. The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression. Biosci Rep. 2016;36:e00299 pubmed 出版商
Arimbasseri A, Blewett N, Iben J, Lamichhane T, Cherkasova V, Hafner M, et al. RNA Polymerase III Output Is Functionally Linked to tRNA Dimethyl-G26 Modification. PLoS Genet. 2015;11:e1005671 pubmed 出版商
López Soldado I, Niisuke K, Veiga C, Adrover A, Manzano A, Martínez Redondo V, et al. Neuregulin improves response to glucose tolerance test in control and diabetic rats. Am J Physiol Endocrinol Metab. 2016;310:E440-51 pubmed 出版商
Tilston Lunel N, Acrani G, Randall R, Elliott R. Generation of Recombinant Oropouche Viruses Lacking the Nonstructural Protein NSm or NSs. J Virol. 2015;90:2616-27 pubmed 出版商
Sujkowski A, Rainier S, Fink J, Wessells R. Delayed Induction of Human NTE (PNPLA6) Rescues Neurodegeneration and Mobility Defects of Drosophila swiss cheese (sws) Mutants. PLoS ONE. 2015;10:e0145356 pubmed 出版商
Lämke J, Brzezinka K, Altmann S, Bäurle I. A hit-and-run heat shock factor governs sustained histone methylation and transcriptional stress memory. EMBO J. 2016;35:162-75 pubmed 出版商
Pazos P, Lima L, Tovar S, González Touceda D, Diéguez C, García M. Divergent responses to thermogenic stimuli in BAT and subcutaneous adipose tissue from interleukin 18 and interleukin 18 receptor 1-deficient mice. Sci Rep. 2015;5:17977 pubmed 出版商
Spiller C, Gillis A, Burnet G, Stoop H, Koopman P, Bowles J, et al. Cripto: Expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors. Mol Oncol. 2016;10:526-37 pubmed 出版商
Rafehi S, Ramos Valdes Y, Bertrand M, McGee J, Préfontaine M, Sugimoto A, et al. TGFβ signaling regulates epithelial-mesenchymal plasticity in ovarian cancer ascites-derived spheroids. Endocr Relat Cancer. 2016;23:147-59 pubmed 出版商
Lastwika K, Wilson W, Li Q, Norris J, Xu H, Ghazarian S, et al. Control of PD-L1 Expression by Oncogenic Activation of the AKT-mTOR Pathway in Non-Small Cell Lung Cancer. Cancer Res. 2016;76:227-38 pubmed 出版商
Suvorova I, Grigorash B, Chuykin I, Pospelova T, Pospelov V. G1 checkpoint is compromised in mouse ESCs due to functional uncoupling of p53-p21Waf1 signaling. Cell Cycle. 2016;15:52-63 pubmed 出版商
Duan S, Yuan G, Liu X, Ren R, Li J, Zhang W, et al. PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype. Nat Commun. 2015;6:10068 pubmed 出版商
Xu Y, Zhao S, Cui M, Wang Q. Down-regulation of microRNA-135b inhibited growth of cervical cancer cells by targeting FOXO1. Int J Clin Exp Pathol. 2015;8:10294-304 pubmed
Ventura S, Aryee D, Felicetti F, De Feo A, Mancarella C, Manara M, et al. CD99 regulates neural differentiation of Ewing sarcoma cells through miR-34a-Notch-mediated control of NF-κB signaling. Oncogene. 2016;35:3944-54 pubmed 出版商
Jang S, Oh D, Lee Y, Hosy E, Shin H, van Riesen C, et al. Synaptic adhesion molecule IgSF11 regulates synaptic transmission and plasticity. Nat Neurosci. 2016;19:84-93 pubmed 出版商
Cerveró C, Montull N, Tarabal O, Piedrafita L, Esquerda J, Calderó J. Chronic Treatment with the AMPK Agonist AICAR Prevents Skeletal Muscle Pathology but Fails to Improve Clinical Outcome in a Mouse Model of Severe Spinal Muscular Atrophy. Neurotherapeutics. 2016;13:198-216 pubmed 出版商
Vesci L, Milazzo F, Anastasi A, Petronzelli F, Chiapparino C, Carollo V, et al. Intra-tumor AvidinOX allows efficacy of low dose systemic biotinylated Cetuximab in a model of head and neck cancer. Oncotarget. 2016;7:914-28 pubmed 出版商
Liao H, Hsu J, Xia W, Wang H, Wang Y, Chang W, et al. PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response. J Clin Invest. 2015;125:4529-43 pubmed 出版商
Quiñones M, Folgueira C, Sánchez Rebordelo E, Al Massadi O. Circulating Irisin Levels Are Not Regulated by Nutritional Status, Obesity, or Leptin Levels in Rodents. Mediators Inflamm. 2015;2015:620919 pubmed 出版商
Murata H, Takamatsu H, Liu S, Kataoka K, Huh N, Sakaguchi M. NRF2 Regulates PINK1 Expression under Oxidative Stress Conditions. PLoS ONE. 2015;10:e0142438 pubmed 出版商
Kamenz J, Mihaljev T, Kubis A, Legewie S, Hauf S. Robust Ordering of Anaphase Events by Adaptive Thresholds and Competing Degradation Pathways. Mol Cell. 2015;60:446-59 pubmed 出版商
Min J, Holden S, Carlini L, Unser M, Manley S, Ye J. 3D high-density localization microscopy using hybrid astigmatic/ biplane imaging and sparse image reconstruction. Biomed Opt Express. 2014;5:3935-48 pubmed 出版商
Maier H, Wang Eckhardt L, Hartmann D, Gieselmann V, Eckhardt M. N-Acetylaspartate Synthase Deficiency Corrects the Myelin Phenotype in a Canavan Disease Mouse Model But Does Not Affect Survival Time. J Neurosci. 2015;35:14501-16 pubmed 出版商
Agarwal S, Kim H, Chan R, Agarwal S, Williamson R, Cho W, et al. Autophagy and endosomal trafficking inhibition by Vibrio cholerae MARTX toxin phosphatidylinositol-3-phosphate-specific phospholipase A1 activity. Nat Commun. 2015;6:8745 pubmed 出版商
Bevilacqua V, Gioia U, Di Carlo V, Tortorelli A, Colombo T, Bozzoni I, et al. Identification of linc-NeD125, a novel long non coding RNA that hosts miR-125b-1 and negatively controls proliferation of human neuroblastoma cells. RNA Biol. 2015;12:1323-37 pubmed 出版商
Kokkinopoulos I, Ishida H, Saba R, Ruchaya P, Cabrera C, Struebig M, et al. Single-Cell Expression Profiling Reveals a Dynamic State of Cardiac Precursor Cells in the Early Mouse Embryo. PLoS ONE. 2015;10:e0140831 pubmed 出版商
Jensen B, Monnerie H, Mannell M, Gannon P, Espinoza C, Erickson M, et al. Altered Oligodendrocyte Maturation and Myelin Maintenance: The Role of Antiretrovirals in HIV-Associated Neurocognitive Disorders. J Neuropathol Exp Neurol. 2015;74:1093-118 pubmed 出版商
Jackson A, Roche S, Byrne A, Ruiz Lopez A, Cotter T. Progesterone receptor signalling in retinal photoreceptor neuroprotection. J Neurochem. 2016;136:63-77 pubmed 出版商
Mitchell M, Denais C, Chan M, Wang Z, Lammerding J, King M. Lamin A/C deficiency reduces circulating tumor cell resistance to fluid shear stress. Am J Physiol Cell Physiol. 2015;309:C736-46 pubmed 出版商
Liu X, Qu X, Jiang Y, Chang M, Zhang R, Wu Y, et al. Profilin Regulates Apical Actin Polymerization to Control Polarized Pollen Tube Growth. Mol Plant. 2015;8:1694-709 pubmed 出版商
Christenson J, Denny E, Kane S. t-Darpp overexpression in HER2-positive breast cancer confers a survival advantage in lapatinib. Oncotarget. 2015;6:33134-45 pubmed 出版商
Pinsino A, Russo R, Bonaventura R, Brunelli A, Marcomini A, Matranga V. Titanium dioxide nanoparticles stimulate sea urchin immune cell phagocytic activity involving TLR/p38 MAPK-mediated signalling pathway. Sci Rep. 2015;5:14492 pubmed 出版商
Lu M, Boschetti C, Tunnacliffe A. Long Term Aggresome Accumulation Leads to DNA Damage, p53-dependent Cell Cycle Arrest, and Steric Interference in Mitosis. J Biol Chem. 2015;290:27986-8000 pubmed 出版商
Garfinkel B, Arad S, Le P, Bustin M, Rosen C, Gabet Y, et al. Proportionate Dwarfism in Mice Lacking Heterochromatin Protein 1 Binding Protein 3 (HP1BP3) Is Associated With Alterations in the Endocrine IGF-1 Pathway. Endocrinology. 2015;156:4558-70 pubmed 出版商
Gleixner A, Posimo J, Pant D, Henderson M, Leak R. Astrocytes Surviving Severe Stress Can Still Protect Neighboring Neurons from Proteotoxic Injury. Mol Neurobiol. 2016;53:4939-60 pubmed 出版商
Teixeira Castro A, Jalles A, Esteves S, Kang S, da Silva Santos L, Silva Fernandes A, et al. Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease. Brain. 2015;138:3221-37 pubmed 出版商
Giacomin P, Moy R, Noti M, Osborne L, Siracusa M, Alenghat T, et al. Epithelial-intrinsic IKKα expression regulates group 3 innate lymphoid cell responses and antibacterial immunity. J Exp Med. 2015;212:1513-28 pubmed 出版商
Komaba S, Coluccio L. Myosin 1b Regulates Amino Acid Transport by Associating Transporters with the Apical Plasma Membrane of Kidney Cells. PLoS ONE. 2015;10:e0138012 pubmed 出版商
Rønningen T, Shah A, Oldenburg A, Vekterud K, Delbarre E, Moskaug J, et al. Prepatterning of differentiation-driven nuclear lamin A/C-associated chromatin domains by GlcNAcylated histone H2B. Genome Res. 2015;25:1825-35 pubmed 出版商
Cochran J, Rush T, Buckingham S, Roberson E. The Alzheimer's disease risk factor CD2AP maintains blood-brain barrier integrity. Hum Mol Genet. 2015;24:6667-74 pubmed 出版商
Liu Y, Li Y, Liu J, Wu Y, Zhu Q. MicroRNA-132 inhibits cell growth and metastasis in osteosarcoma cell lines possibly by targeting Sox4. Int J Oncol. 2015;47:1672-84 pubmed 出版商
Yoo S, Kim H, Rho J, Jeong S, Yun J, Yun I, et al. Targeted inhibition of mitochondrial Hsp90 induces mitochondrial elongation in Hep3B hepatocellular carcinoma cells undergoing apoptosis by increasing the ROS level. Int J Oncol. 2015;47:1783-92 pubmed 出版商
van der Tuin S, Kühnast S, Berbée J, Verschuren L, Pieterman E, Havekes L, et al. Anacetrapib reduces (V)LDL cholesterol by inhibition of CETP activity and reduction of plasma PCSK9. J Lipid Res. 2015;56:2085-93 pubmed 出版商
Leinhäuser I, Richter A, Lee M, Höfig I, Anastasov N, Fend F, et al. Oncogenic features of the bone morphogenic protein 7 (BMP7) in pheochromocytoma. Oncotarget. 2015;6:39111-26 pubmed 出版商
Caputo L, Witzel H, Kolovos P, Cheedipudi S, Looso M, Mylona A, et al. The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors. Cell Stem Cell. 2015;17:287-99 pubmed 出版商
Sato T, Ishikawa M, Yoshihara T, Nakazato R, Higashida H, Asano M, et al. Critical role of JSAP1 and JLP in axonal transport in the cerebellar Purkinje cells of mice. FEBS Lett. 2015;589:2805-11 pubmed 出版商
Bernard K, Logsdon N, Ravi S, Xie N, Persons B, Rangarajan S, et al. Metabolic Reprogramming Is Required for Myofibroblast Contractility and Differentiation. J Biol Chem. 2015;290:25427-38 pubmed 出版商
Tuncay H, Brinkmann B, Steinbacher T, Schürmann A, Gerke V, Iden S, et al. JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis. Nat Commun. 2015;6:8128 pubmed 出版商
Xiao L, Xian H, Lee K, Xiao B, Wang H, Yu F, et al. Death-associated Protein 3 Regulates Mitochondrial-encoded Protein Synthesis and Mitochondrial Dynamics. J Biol Chem. 2015;290:24961-74 pubmed 出版商
Tan B, Mu R, Chang Y, Wang Y, Wu M, Tu H, et al. RNF4 negatively regulates NF-κB signaling by down-regulating TAB2. FEBS Lett. 2015;589:2850-8 pubmed 出版商
Flores H, Bubnell J, Aquadro C, Barbash D. The Drosophila bag of marbles Gene Interacts Genetically with Wolbachia and Shows Female-Specific Effects of Divergence. PLoS Genet. 2015;11:e1005453 pubmed 出版商
Kruiswijk F, Hasenfuss S, Sivapatham R, Baar M, Putavet D, Naipal K, et al. Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling. Oncogene. 2016;35:2166-77 pubmed 出版商
Hattori T, Watanabe Takahashi M, Ohoka N, Hamabata T, Furukawa K, Nishikawa K, et al. Proteasome inhibitors prevent cell death and prolong survival of mice challenged by Shiga toxin. FEBS Open Bio. 2015;5:605-14 pubmed 出版商
Singh D, Spillane C, Siddiqi I. PATRONUS1 is expressed in meiotic prophase I to regulate centromeric cohesion in Arabidopsis and shows synthetic lethality with OSD1. BMC Plant Biol. 2015;15:201 pubmed 出版商
Mikhaylova M, Cloin B, Finan K, van den Berg R, Teeuw J, Kijanka M, et al. Resolving bundled microtubules using anti-tubulin nanobodies. Nat Commun. 2015;6:7933 pubmed 出版商
Lin S, Ewen Campen B, Ni X, Housden B, Perrimon N. In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila. Genetics. 2015;201:433-42 pubmed 出版商
Mendus D, Rankin Gee E, Mustapha M, Porter B. Increased sensitivity to kindling in mice lacking TSP1. Neuroscience. 2015;305:302-8 pubmed 出版商
Li Y, Peng L, Seto E. Histone Deacetylase 10 Regulates the Cell Cycle G2/M Phase Transition via a Novel Let-7-HMGA2-Cyclin A2 Pathway. Mol Cell Biol. 2015;35:3547-65 pubmed 出版商
Wandrey F, Montellese C, Koos K, Badertscher L, Bammert L, Cook A, et al. The NF45/NF90 Heterodimer Contributes to the Biogenesis of 60S Ribosomal Subunits and Influences Nucleolar Morphology. Mol Cell Biol. 2015;35:3491-503 pubmed 出版商
Ishihara Y, Takemoto T, Itoh K, Ishida A, Yamazaki T. Dual role of superoxide dismutase 2 induced in activated microglia: oxidative stress tolerance and convergence of inflammatory responses. J Biol Chem. 2015;290:22805-17 pubmed 出版商
Capel F, Chabrier G, Pitois E, Rigaudière J, Le Plenier S, Durand C, et al. Combining citrulline with atorvastatin preserves glucose homeostasis in a murine model of diet-induced obesity. Br J Pharmacol. 2015;172:4996-5008 pubmed 出版商
Chang K, Anishkin A, Patwardhan G, Beverly L, Siskind L, Colombini M. Ceramide channels: destabilization by Bcl-xL and role in apoptosis. Biochim Biophys Acta. 2015;1848:2374-84 pubmed 出版商
Ying X, Jing L, Ma S, Li Q, Luo X, Pan Z, et al. GSK3β mediates pancreatic cancer cell invasion in vitro via the CXCR4/MMP-2 Pathway. Cancer Cell Int. 2015;15:70 pubmed 出版商
Kokkola T, Suuronen T, Pesonen M, Filippakopoulos P, Salminen A, Jarho E, et al. BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses. Chembiochem. 2015;16:1997-2001 pubmed 出版商
Drießen S, Berleth N, Friesen O, Löffler A, Böhler P, Hieke N, et al. Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy. Autophagy. 2015;11:1458-70 pubmed 出版商
Ryan C, Brown J, Bourke E, Prendergast Ã, Kavanagh C, Liu Z, et al. ROCK activity and the Gβγ complex mediate chemotactic migration of mouse bone marrow-derived stromal cells. Stem Cell Res Ther. 2015;6:136 pubmed 出版商
Eiring A, Khorashad J, Anderson D, Yu F, Redwine H, Mason C, et al. β-Catenin is required for intrinsic but not extrinsic BCR-ABL1 kinase-independent resistance to tyrosine kinase inhibitors in chronic myeloid leukemia. Leukemia. 2015;29:2328-37 pubmed 出版商
Zeng Z, Huang W, Gao Q, Su M, Yang Y, Liu Z, et al. Arnebin-1 promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway. Int J Mol Med. 2015;36:685-97 pubmed 出版商
Shimoda Y, Okada S, Yamada E, Pessin J, Yamada M. Tctex1d2 Is a Negative Regulator of GLUT4 Translocation and Glucose Uptake. Endocrinology. 2015;156:3548-58 pubmed 出版商
Yin H, Frontini M, Arpino J, Nong Z, O Neil C, Xu Y, et al. Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases. J Biol Chem. 2015;290:22127-42 pubmed 出版商
Shi Y, Yuan B, Qi N, Zhu W, Su J, Li X, et al. An autoinhibitory mechanism modulates MAVS activity in antiviral innate immune response. Nat Commun. 2015;6:7811 pubmed 出版商
Hu T, Yeh J, Pinello L, Jacob J, Chakravarthy S, Yuan G, et al. Impact of the N-Terminal Domain of STAT3 in STAT3-Dependent Transcriptional Activity. Mol Cell Biol. 2015;35:3284-300 pubmed 出版商
Rein K, Yanez D, Terré B, Palenzuela L, Aivio S, Wei K, et al. EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele. Nucleic Acids Res. 2015;43:7371-87 pubmed 出版商
Papini D, Langemeyer L, Abad M, Kerr A, Samejima I, Eyers P, et al. TD-60 links RalA GTPase function to the CPC in mitosis. Nat Commun. 2015;6:7678 pubmed 出版商
Stayrook K, Mack J, Cerabona D, Edwards D, Bui H, Niewolna M, et al. TGFβ-Mediated induction of SphK1 as a potential determinant in human MDA-MB-231 breast cancer cell bone metastasis. Bonekey Rep. 2015;4:719 pubmed 出版商
Mouguelar V, Coux G. Activation of spleen tyrosine kinase (Syk) at fertilization in Rhinella arenarum eggs. Int J Dev Biol. 2014;58:811-8 pubmed 出版商
Abuhatzira L, Xu H, Tahhan G, Boulougoura A, Schäffer A, Notkins A. Multiple microRNAs within the 14q32 cluster target the mRNAs of major type 1 diabetes autoantigens IA-2, IA-2β, and GAD65. FASEB J. 2015;29:4374-83 pubmed 出版商
Denny E, Kane S. t-Darpp Promotes Enhanced EGFR Activation and New Drug Synergies in Her2-Positive Breast Cancer Cells. PLoS ONE. 2015;10:e0132267 pubmed 出版商
ToruÅ„ A, SzymaÅ„ska E, Castanon I, WoliÅ„ska NizioÅ‚ L, Bartosik A, JastrzÄ™bski K, et al. Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling. PLoS ONE. 2015;10:e0130818 pubmed 出版商
Cáceres M, Ortiz L, Recabarren T, Romero A, Colombo A, Leiva Salcedo E, et al. TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility. PLoS ONE. 2015;10:e0130540 pubmed 出版商
Uren P, Vo D, de Araújo P, Pötschke R, Burns S, Bahrami Samani E, et al. RNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma. Mol Cell Biol. 2015;35:2965-78 pubmed 出版商
Kim M, Semple I, Kim B, Kiers A, Nam S, Park H, et al. Drosophila Gyf/GRB10 interacting GYF protein is an autophagy regulator that controls neuron and muscle homeostasis. Autophagy. 2015;11:1358-72 pubmed 出版商
Jacinto F, Benner C, Hetzer M. The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing. Genes Dev. 2015;29:1224-38 pubmed 出版商
Renard H, Garcia Castillo M, Chambon V, Lamaze C, Johannes L. Shiga toxin stimulates clathrin-independent endocytosis of the VAMP2, VAMP3 and VAMP8 SNARE proteins. J Cell Sci. 2015;128:2891-902 pubmed 出版商
Pan L, Hildebrand K, Stutz C, Thomä N, Baumann P. Minishelterins separate telomere length regulation and end protection in fission yeast. Genes Dev. 2015;29:1164-74 pubmed 出版商
Ghule P, Xie R, Colby J, Jones S, Lian J, Wijnen A, et al. p53 checkpoint ablation exacerbates the phenotype of Hinfp dependent histone H4 deficiency. Cell Cycle. 2015;14:2501-8 pubmed 出版商
Lin Y, Long J, Huang F, Duim W, Kirschbaum S, Zhang Y, et al. Quantifying and optimizing single-molecule switching nanoscopy at high speeds. PLoS ONE. 2015;10:e0128135 pubmed 出版商
Tsou W, Ouyang M, Hosking R, Sutton J, Blount J, Burr A, et al. The deubiquitinase ataxin-3 requires Rad23 and DnaJ-1 for its neuroprotective role in Drosophila melanogaster. Neurobiol Dis. 2015;82:12-21 pubmed 出版商
Codenotti S, Battistelli M, Burattini S, Salucci S, Falcieri E, Rezzani R, et al. Melatonin decreases cell proliferation, impairs myogenic differentiation and triggers apoptotic cell death in rhabdomyosarcoma cell lines. Oncol Rep. 2015;34:279-87 pubmed 出版商
Liu C, Lou W, Armstrong C, Zhu Y, Evans C, Gao A. Niclosamide suppresses cell migration and invasion in enzalutamide resistant prostate cancer cells via Stat3-AR axis inhibition. Prostate. 2015;75:1341-53 pubmed 出版商
Miron K, Golan Lev T, Dvir R, Ben David E, Kerem B. Oncogenes create a unique landscape of fragile sites. Nat Commun. 2015;6:7094 pubmed 出版商
Ba Z, Meng F, Gostissa M, Huang P, Ke Q, Wang Z, et al. A Rapid Embryonic Stem Cell-Based Mouse Model for B-cell Lymphomas Driven by Epstein-Barr Virus Protein LMP1. Cancer Immunol Res. 2015;3:641-9 pubmed 出版商
Lan L, Appelman C, Smith A, Yu J, Larsen S, Marquez R, et al. Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1. Mol Oncol. 2015;9:1406-20 pubmed 出版商
Yang N, Gilman P, Mirzayans R, Sun X, Touret N, Weinfeld M, et al. Characterization of the apoptotic response induced by the cyanine dye D112: a potentially selective anti-cancer compound. PLoS ONE. 2015;10:e0125381 pubmed 出版商
Kajikawa M, Sawaragi Y, Shinkawa H, Yamano T, Ando A, Kato M, et al. Algal dual-specificity tyrosine phosphorylation-regulated kinase, triacylglycerol accumulation regulator1, regulates accumulation of triacylglycerol in nitrogen or sulfur deficiency. Plant Physiol. 2015;168:752-64 pubmed 出版商
Brown Clay J, Shenoy D, Timofeeva O, Kallakury B, Nandi A, Banerjee P. PBK/TOPK enhances aggressive phenotype in prostate cancer via β-catenin-TCF/LEF-mediated matrix metalloproteinases production and invasion. Oncotarget. 2015;6:15594-609 pubmed
Stein A, Stroobants S, Gieselmann V, D Hooge R, Matzner U. Anti-inflammatory Therapy With Simvastatin Improves Neuroinflammation and CNS Function in a Mouse Model of Metachromatic Leukodystrophy. Mol Ther. 2015;23:1160-1168 pubmed 出版商
Rebucci M, Sermeus A, Leonard E, Delaive E, Dieu M, Fransolet M, et al. miRNA-196b inhibits cell proliferation and induces apoptosis in HepG2 cells by targeting IGF2BP1. Mol Cancer. 2015;14:79 pubmed 出版商
Fahrenkamp D, de Leur H, Küster A, Chatain N, Müller Newen G. Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction. Cell Commun Signal. 2015;13:10 pubmed 出版商
Szabó A, Xiao X, Haughney M, Spector A, Sahin Tóth M, Lowe M. A novel mutation in PNLIP causes pancreatic triglyceride lipase deficiency through protein misfolding. Biochim Biophys Acta. 2015;1852:1372-9 pubmed 出版商
Wang Z, Rabouille C, Geisbrecht E. Loss of a Clueless-dGRASP complex results in ER stress and blocks Integrin exit from the perinuclear endoplasmic reticulum in Drosophila larval muscle. Biol Open. 2015;4:636-48 pubmed 出版商
Zhang B, Zhang T, Wang G, Wang G, Chi W, Jiang Q, et al. GSK3β-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis. PLoS Biol. 2015;13:e1002129 pubmed 出版商
Cramer S, Popa L, Carter R, Chen G, Ebner T. Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse. J Neurosci. 2015;35:5664-79 pubmed 出版商
Gonnella R, Granato M, Farina A, Santarelli R, Faggioni A, Cirone M. PKC theta and p38 MAPK activate the EBV lytic cycle through autophagy induction. Biochim Biophys Acta. 2015;1853:1586-95 pubmed 出版商
Pardo V, González Rodríguez Ã, Guijas C, Balsinde J, Valverde Ã. Opposite cross-talk by oleate and palmitate on insulin signaling in hepatocytes through macrophage activation. J Biol Chem. 2015;290:11663-77 pubmed 出版商
Mojica S, Hovis K, Frieman M, Tran B, Hsia R, Ravel J, et al. SINC, a type III secreted protein of Chlamydia psittaci, targets the inner nuclear membrane of infected cells and uninfected neighbors. Mol Biol Cell. 2015;26:1918-34 pubmed 出版商
Huang X, Leggas M, Dickson R. Drug synergy drives conserved pathways to increase fission yeast lifespan. PLoS ONE. 2015;10:e0121877 pubmed 出版商
Okamoto A, Yabuta N, Mukai S, Torigata K, Nojima H. Phosphorylation of CHO1 by Lats1/2 regulates the centrosomal activation of LIMK1 during cytokinesis. Cell Cycle. 2015;14:1568-82 pubmed 出版商
Sutherland J, Sobinoff A, Fraser B, Redgrove K, Davidson T, Siddall N, et al. RNA binding protein Musashi-1 directly targets Msi2 and Erh during early testis germ cell development and interacts with IPO5 upon translocation to the nucleus. FASEB J. 2015;29:2759-68 pubmed 出版商
Hsu P, Xu B, Mukai J, Karayiorgou M, Gogos J. The BDNF Val66Met variant affects gene expression through miR-146b. Neurobiol Dis. 2015;77:228-37 pubmed 出版商
Fang X, Shi Y, Lu X, Chen Z, Qi Y. CMA33/XCT Regulates Small RNA Production through Modulating the Transcription of Dicer-Like Genes in Arabidopsis. Mol Plant. 2015;8:1227-36 pubmed 出版商
Broderick R, Nieminuszczy J, Blackford A, Winczura A, Niedzwiedz W. TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution. Nat Commun. 2015;6:6572 pubmed 出版商
Sopko R, Lin Y, Makhijani K, Alexander B, Perrimon N, Brückner K. A systems-level interrogation identifies regulators of Drosophila blood cell number and survival. PLoS Genet. 2015;11:e1005056 pubmed 出版商
van Knippenberg I, Elliott R. Flexibility of bunyavirus genomes: creation of an orthobunyavirus with an ambisense S segment. J Virol. 2015;89:5525-35 pubmed 出版商
Dhir A, Dhir S, Proudfoot N, Jopling C. Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs. Nat Struct Mol Biol. 2015;22:319-27 pubmed 出版商
Bindesbøll C, Fan Q, Nørgaard R, MacPherson L, Ruan H, Wu J, et al. Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity. J Lipid Res. 2015;56:771-85 pubmed 出版商
Schweitzer G, Chen Z, Gan C, McCommis K, Soufi N, Chrast R, et al. Liver-specific loss of lipin-1-mediated phosphatidic acid phosphatase activity does not mitigate intrahepatic TG accumulation in mice. J Lipid Res. 2015;56:848-58 pubmed 出版商
Le Gal L, Alonso F, Mazzolai L, Meda P, Haefliger J. Interplay between connexin40 and nitric oxide signaling during hypertension. Hypertension. 2015;65:910-5 pubmed 出版商
von Alpen D, Tran H, Guex N, Venturini G, Munier F, Schorderet D, et al. Differential dimerization of variants linked to enhanced S-cone sensitivity syndrome (ESCS) located in the NR2E3 ligand-binding domain. Hum Mutat. 2015;36:599-610 pubmed 出版商
Hu J, Huang X, Chen L, Sun X, Lu C, Zhang L, et al. Site-specific nitrosoproteomic identification of endogenously S-nitrosylated proteins in Arabidopsis. Plant Physiol. 2015;167:1731-46 pubmed 出版商
Major A, Hogarth C, Miyamoto Y, Sarraj M, Smith C, Koopman P, et al. Specific interaction with the nuclear transporter importin α2 can modulate paraspeckle protein 1 delivery to nuclear paraspeckles. Mol Biol Cell. 2015;26:1543-58 pubmed 出版商
Wu J, Yang Z, Wang Y, Zheng L, Ye R, Ji Y, et al. Viral-inducible Argonaute18 confers broad-spectrum virus resistance in rice by sequestering a host microRNA. elife. 2015;4: pubmed 出版商
Coll R, Robertson A, Chae J, Higgins S, Muñoz Planillo R, Inserra M, et al. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat Med. 2015;21:248-55 pubmed 出版商
Komai K, Niwa Y, Sasazawa Y, Simizu S. Pirin regulates epithelial to mesenchymal transition independently of Bcl3-Slug signaling. FEBS Lett. 2015;589:738-43 pubmed 出版商
Vogel G, Ebner H, de Araujo M, Schmiedinger T, Eiter O, Pircher H, et al. Ultrastructural Morphometry Points to a New Role for LAMTOR2 in Regulating the Endo/Lysosomal System. Traffic. 2015;16:617-34 pubmed 出版商
Rezelj V, Överby A, Elliott R. Generation of mutant Uukuniemi viruses lacking the nonstructural protein NSs by reverse genetics indicates that NSs is a weak interferon antagonist. J Virol. 2015;89:4849-56 pubmed 出版商
Gomi H, Morikawa S, Shinmura N, Moki H, Yasui T, Tsukise A, et al. Expression of Secretogranin III in Chicken Endocrine Cells: Its Relevance to the Secretory Granule Properties of Peptide Prohormone Processing and Bioactive Amine Content. J Histochem Cytochem. 2015;63:350-66 pubmed 出版商
Rumpf T, Schiedel M, Karaman B, Roessler C, North B, Lehotzky A, et al. Selective Sirt2 inhibition by ligand-induced rearrangement of the active site. Nat Commun. 2015;6:6263 pubmed 出版商
Yang H, Mu J, Chen L, Feng J, Hu J, Li L, et al. S-nitrosylation positively regulates ascorbate peroxidase activity during plant stress responses. Plant Physiol. 2015;167:1604-15 pubmed 出版商
Garfinkel B, Melamed Book N, Anuka E, Bustin M, Orly J. HP1BP3 is a novel histone H1 related protein with essential roles in viability and growth. Nucleic Acids Res. 2015;43:2074-90 pubmed 出版商
Raju P, Nyamsuren G, Elkenani M, Kata A, Tsagaan E, Engel W, et al. Pelota mediates gonocyte maturation and maintenance of spermatogonial stem cells in mouse testes. Reproduction. 2015;149:213-21 pubmed 出版商
Liu C, Lou W, Zhu Y, Yang J, Nadiminty N, Gaikwad N, et al. Intracrine Androgens and AKR1C3 Activation Confer Resistance to Enzalutamide in Prostate Cancer. Cancer Res. 2015;75:1413-22 pubmed 出版商
Johnstone C, Smith Y, Cao Y, Burrows A, Cross R, Ling X, et al. Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer. Dis Model Mech. 2015;8:237-51 pubmed 出版商
Wheatley S. The functional repertoire of survivin's tails. Cell Cycle. 2015;14:261-8 pubmed 出版商
Spinazzola J, Smith T, Liu M, Luna E, Barton E. Gamma-sarcoglycan is required for the response of archvillin to mechanical stimulation in skeletal muscle. Hum Mol Genet. 2015;24:2470-81 pubmed 出版商
Van Bockstal M, Lambein K, Van Gele M, De Vlieghere E, Limame R, Braems G, et al. Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion. Oncoscience. 2014;1:634-48 pubmed
Yanagi T, Reed J, Matsuzawa S. PCTAIRE1 regulates p27 stability, apoptosis and tumor growth in malignant melanoma. Oncoscience. 2014;1:624-33 pubmed
Munkley J, Lafferty N, Kalna G, Robson C, Leung H, Rajan P, et al. Androgen-regulation of the protein tyrosine phosphatase PTPRR activates ERK1/2 signalling in prostate cancer cells. BMC Cancer. 2015;15:9 pubmed 出版商
Pircher H, von Grafenstein S, Diener T, Metzger C, Albertini E, Taferner A, et al. Identification of FAH domain-containing protein 1 (FAHD1) as oxaloacetate decarboxylase. J Biol Chem. 2015;290:6755-62 pubmed 出版商
Sato T, Ishikawa M, Mochizuki M, Ohta M, Ohkura M, Nakai J, et al. JSAP1/JIP3 and JLP regulate kinesin-1-dependent axonal transport to prevent neuronal degeneration. Cell Death Differ. 2015;22:1260-74 pubmed 出版商
Tomida J, Takata K, Lange S, Schibler A, Yousefzadeh M, Bhetawal S, et al. REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ?. Nucleic Acids Res. 2015;43:1000-11 pubmed 出版商
Xin Y, Yuan B, Yu B, Wang Y, Wu J, Zhou W, et al. Tet1-mediated DNA demethylation regulates neuronal cell death induced by oxidative stress. Sci Rep. 2015;5:7645 pubmed 出版商
Susa T, Ikaga R, Kajitani T, Iizuka M, Okinaga H, Tamamori Adachi M, et al. Wild-type and specific mutant androgen receptor mediates transcription via 17β-estradiol in sex hormone-sensitive cancer cells. J Cell Physiol. 2015;230:1594-606 pubmed 出版商
Gianfelice A, Le P, Rigano L, Saila S, Dowd G, McDivitt T, et al. Host endoplasmic reticulum COPII proteins control cell-to-cell spread of the bacterial pathogen Listeria monocytogenes. Cell Microbiol. 2015;17:876-92 pubmed 出版商
Hennig D, Müller S, Wichmann C, Drube S, Pietschmann K, Pelzl L, et al. Antagonism between granulocytic maturation and deacetylase inhibitor-induced apoptosis in acute promyelocytic leukaemia cells. Br J Cancer. 2015;112:329-37 pubmed 出版商
Frock R, Hu J, Meyers R, Ho Y, Kii E, Alt F. Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases. Nat Biotechnol. 2015;33:179-86 pubmed 出版商
Brownlow N, Pike T, Zicha D, Collinson L, Parker P. Mitotic catenation is monitored and resolved by a PKCε-regulated pathway. Nat Commun. 2014;5:5685 pubmed 出版商
Palagani A, Op de Beeck K, Naulaerts S, Diddens J, Sekhar Chirumamilla C, Van Camp G, et al. Ectopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cells. PLoS ONE. 2014;9:e113842 pubmed 出版商
Galoian K, Qureshi A, Wideroff G, Temple H. Restoration of desmosomal junction protein expression and inhibition of H3K9-specific histone demethylase activity by cytostatic proline-rich polypeptide-1 leads to suppression of tumorigenic potential in human chondrosarcoma cells. Mol Clin Oncol. 2015;3:171-178 pubmed
Wang Y, Wang Z. Efficient backsplicing produces translatable circular mRNAs. RNA. 2015;21:172-9 pubmed 出版商
Kuang Z, Huang Z, Li Y, Yang G, Liu M, Yuan H. Overexpression of CYP3A5 attenuates inducibility and activity of CYP3A4 in HepG2 cells. Mol Med Rep. 2015;11:2868-74 pubmed 出版商
Zhang L, Huang H, Zhang L, Hou T, Wu S, Huang Q, et al. URG4 overexpression is correlated with cervical cancer progression and poor prognosis in patients with early-stage cervical cancer. BMC Cancer. 2014;14:885 pubmed 出版商
Liu Z, Shen M, Wu W, Li B, Weng Q, Li M, et al. Expression of PUMA in Follicular Granulosa Cells Regulated by FoxO1 Activation During Oxidative Stress. Reprod Sci. 2015;22:696-705 pubmed 出版商
Kedashiro S, Pastuhov S, Nishioka T, Watanabe T, Kaibuchi K, Matsumoto K, et al. LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends. J Cell Sci. 2015;128:385-96 pubmed 出版商
Richter C, Viergutz T, Schwerin M, Weitzel J. Prostaglandin E synthase interacts with inducible heat shock protein 70 after heat stress in bovine primary dermal fibroblast cells. Cytometry A. 2015;87:61-7 pubmed 出版商
Reusch J, Nawandar D, Wright K, Kenney S, Mertz J. Cellular differentiation regulator BLIMP1 induces Epstein-Barr virus lytic reactivation in epithelial and B cells by activating transcription from both the R and Z promoters. J Virol. 2015;89:1731-43 pubmed 出版商
BOWMAN C, Ayer D, Dynlacht B. Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs. Nat Cell Biol. 2014;16:1202-14 pubmed 出版商
Shiratsuchi G, Takaoka K, Ashikawa T, Hamada H, Kitagawa D. RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity. EMBO J. 2015;34:97-114 pubmed 出版商
Seifert T, Malo M, Kokkola T, Engen K, Fridén Saxin M, Wallén E, et al. Chroman-4-one- and chromone-based sirtuin 2 inhibitors with antiproliferative properties in cancer cells. J Med Chem. 2014;57:9870-88 pubmed 出版商
Hugosson F, Sjögren C, Birve A, Hedlund L, Eriksson T, Palmer R. The Drosophila midkine/pleiotrophin homologues Miple1 and Miple2 affect adult lifespan but are dispensable for alk signaling during embryonic gut formation. PLoS ONE. 2014;9:e112250 pubmed 出版商
Alique M, Sánchez López E, Rayego Mateos S, Egido J, Ortiz A, Ruiz Ortega M. Angiotensin II, via angiotensin receptor type 1/nuclear factor-κB activation, causes a synergistic effect on interleukin-1-β-induced inflammatory responses in cultured mesangial cells. J Renin Angiotensin Aldosterone Syst. 2015;16:23-32 pubmed 出版商
Sun Q, Cibas E, Huang H, Hodgson L, Overholtzer M. Induction of entosis by epithelial cadherin expression. Cell Res. 2014;24:1288-98 pubmed 出版商
Dombert B, Sivadasan R, Simon C, Jablonka S, Sendtner M. Presynaptic localization of Smn and hnRNP R in axon terminals of embryonic and postnatal mouse motoneurons. PLoS ONE. 2014;9:e110846 pubmed 出版商
Bremmer F, Jarry H, Strauß A, Behnes C, Trojan L, Thelen P. Increased expression of CYP17A1 indicates an effective targeting of the androgen receptor axis in castration resistant prostate cancer (CRPC). Springerplus. 2014;3:574 pubmed 出版商
DaRosa P, Wang Z, Jiang X, Pruneda J, Cong F, Klevit R, et al. Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal. Nature. 2015;517:223-6 pubmed 出版商
Aughey G, Grice S, Shen Q, Xu Y, Chang C, Azzam G, et al. Nucleotide synthesis is regulated by cytoophidium formation during neurodevelopment and adaptive metabolism. Biol Open. 2014;3:1045-56 pubmed 出版商
Henry R, Kuo Y, Bhattacharjee V, Yen T, Andrews A. Changing the selectivity of p300 by acetyl-CoA modulation of histone acetylation. ACS Chem Biol. 2015;10:146-56 pubmed 出版商
Li Y, Arao Y, Hall J, Burkett S, Liu L, Gerrish K, et al. Research Resource: STR DNA profile and gene expression comparisons of human BG-1 cells and a BG-1/MCF-7 clonal variant. Mol Endocrinol. 2014;28:2072-81 pubmed 出版商
Pedraza N, Ortiz R, Cornadó A, Llobet A, Aldea M, Gallego C. KIS, a kinase associated with microtubule regulators, enhances translation of AMPA receptors and stimulates dendritic spine remodeling. J Neurosci. 2014;34:13988-97 pubmed 出版商
Mihailovska E, Raith M, Valencia R, Fischer I, Al Banchaabouchi M, Herbst R, et al. Neuromuscular synapse integrity requires linkage of acetylcholine receptors to postsynaptic intermediate filament networks via rapsyn-plectin 1f complexes. Mol Biol Cell. 2014;25:4130-49 pubmed 出版商
Pernet L, Faure V, Gilquin B, Dufour Guérin S, Khochbin S, Vourc h C. HDAC6-ubiquitin interaction controls the duration of HSF1 activation after heat shock. Mol Biol Cell. 2014;25:4187-94 pubmed 出版商
Cheng S, LeBlanc K, Li L. Triptolide preserves cognitive function and reduces neuropathology in a mouse model of Alzheimer's disease. PLoS ONE. 2014;9:e108845 pubmed 出版商
Waraky A, Akopyan K, Parrow V, Strömberg T, Axelson M, Abrahmsén L, et al. Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via insulin-like growth factor-1 receptor-independent mechanism. Oncotarget. 2014;5:8379-92 pubmed
Millonigg S, Minasaki R, Nousch M, Novak J, Eckmann C. GLD-4-mediated translational activation regulates the size of the proliferative germ cell pool in the adult C. elegans germ line. PLoS Genet. 2014;10:e1004647 pubmed 出版商
Momose I, Abe H, Watanabe T, Ohba S, Yamazaki K, Dan S, et al. Antitumor effects of tyropeptin-boronic acid derivatives: New proteasome inhibitors. Cancer Sci. 2014;105:1609-15 pubmed 出版商
Gasparini F, Caicci F, Rigon F, Zaniolo G, Manni L. Testing an unusual in vivo vessel network model: a method to study angiogenesis in the colonial tunicate Botryllus schlosseri. Sci Rep. 2014;4:6460 pubmed 出版商
De Santis R, Rosi A, Anastasi A, Chiapparino C, Albertoni C, Leoni B, et al. Efficacy of aerosol therapy of lung cancer correlates with EGFR paralysis induced by AvidinOX-anchored biotinylated Cetuximab. Oncotarget. 2014;5:9239-55 pubmed
Brai E, Marathe S, Zentilin L, Giacca M, Nimpf J, Kretz R, et al. Notch1 activity in the olfactory bulb is odour-dependent and contributes to olfactory behaviour. Eur J Neurosci. 2014;40:3436-49 pubmed 出版商
Nousch M, Yeroslaviz A, Habermann B, Eckmann C. The cytoplasmic poly(A) polymerases GLD-2 and GLD-4 promote general gene expression via distinct mechanisms. Nucleic Acids Res. 2014;42:11622-33 pubmed 出版商
Masiello M, Cucina A, Proietti S, Palombo A, Coluccia P, D Anselmi F, et al. Phenotypic switch induced by simulated microgravity on MDA-MB-231 breast cancer cells. Biomed Res Int. 2014;2014:652434 pubmed 出版商
Ducroux A, Benhenda S, Rivière L, Semmes O, Benkirane M, Neuveut C. The Tudor domain protein Spindlin1 is involved in intrinsic antiviral defense against incoming hepatitis B Virus and herpes simplex virus type 1. PLoS Pathog. 2014;10:e1004343 pubmed 出版商
Best A, James K, Dalgliesh C, Hong E, Kheirolahi Kouhestani M, Curk T, et al. Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons. Nat Commun. 2014;5:4760 pubmed 出版商
Sewduth R, Jaspard Vinassa B, Peghaire C, Guillabert A, Franzl N, Larrieu Lahargue F, et al. The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling. Nat Commun. 2014;5:4832 pubmed 出版商
Nishibuchi G, Shibata Y, Hayakawa T, Hayakawa N, Ohtani Y, Sinmyozu K, et al. Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex. J Biol Chem. 2014;289:28956-70 pubmed 出版商
Park H, Park H, Semple I, Jang I, Ro S, Kim M, et al. Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers. Nat Commun. 2014;5:4834 pubmed 出版商
Bailey S, Zhou B, Damrauer J, Krishnan B, Wilson H, Smith A, et al. mTOR inhibition induces compensatory, therapeutically targetable MEK activation in renal cell carcinoma. PLoS ONE. 2014;9:e104413 pubmed 出版商
Wu G, Cai J, Han Y, Chen J, Huang Z, Chen C, et al. LincRNA-p21 regulates neointima formation, vascular smooth muscle cell proliferation, apoptosis, and atherosclerosis by enhancing p53 activity. Circulation. 2014;130:1452-1465 pubmed 出版商
Sutinen E, Korolainen M, Häyrinen J, Alafuzoff I, Petratos S, Salminen A, et al. Interleukin-18 alters protein expressions of neurodegenerative diseases-linked proteins in human SH-SY5Y neuron-like cells. Front Cell Neurosci. 2014;8:214 pubmed 出版商
Stathem M, Marimuthu S, O Neal J, Rathmell J, CHESNEY J, Beverly L, et al. Glucose availability and glycolytic metabolism dictate glycosphingolipid levels. J Cell Biochem. 2015;116:67-80 pubmed 出版商
Blount J, Tsou W, Ristić G, Burr A, Ouyang M, Galante H, et al. Ubiquitin-binding site 2 of ataxin-3 prevents its proteasomal degradation by interacting with Rad23. Nat Commun. 2014;5:4638 pubmed 出版商
Granato M, Santarelli R, Farina A, Gonnella R, Lotti L, Faggioni A, et al. Epstein-barr virus blocks the autophagic flux and appropriates the autophagic machinery to enhance viral replication. J Virol. 2014;88:12715-26 pubmed 出版商
Kao T, Chu C, Lee G, Hsiao T, Cheng N, Chang N, et al. Folate deficiency-induced oxidative stress contributes to neuropathy in young and aged zebrafish--implication in neural tube defects and Alzheimer's diseases. Neurobiol Dis. 2014;71:234-44 pubmed 出版商
Lorenzo F, Huff C, Myllymäki M, Olenchock B, Swierczek S, Tashi T, et al. A genetic mechanism for Tibetan high-altitude adaptation. Nat Genet. 2014;46:951-6 pubmed 出版商
Christenson J, Kane S. Darpp-32 and t-Darpp are differentially expressed in normal and malignant mouse mammary tissue. Mol Cancer. 2014;13:192 pubmed 出版商
Luo X, Tai W, Sun L, Qiu Q, Xia Z, Chung S, et al. Central administration of C-X-C chemokine receptor type 4 antagonist alleviates the development and maintenance of peripheral neuropathic pain in mice. PLoS ONE. 2014;9:e104860 pubmed 出版商
Bagci H, Laurin M, Huber J, Muller W, Côté J. Impaired cell death and mammary gland involution in the absence of Dock1 and Rac1 signaling. Cell Death Dis. 2014;5:e1375 pubmed 出版商
Gao Y, Zhang W, Han X, Li F, Wang X, Wang R, et al. YAP inhibits squamous transdifferentiation of Lkb1-deficient lung adenocarcinoma through ZEB2-dependent DNp63 repression. Nat Commun. 2014;5:4629 pubmed 出版商
Hua K, Wang M, Chen M, Wei L, Chen C, Ko C, et al. The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasis. Mol Cancer. 2014;13:189 pubmed 出版商
Felician G, Collesi C, Lusic M, Martinelli V, Ferro M, Zentilin L, et al. Epigenetic modification at Notch responsive promoters blunts efficacy of inducing notch pathway reactivation after myocardial infarction. Circ Res. 2014;115:636-49 pubmed 出版商
Herzog V, Lempradl A, Trupke J, Okulski H, Altmutter C, Ruge F, et al. A strand-specific switch in noncoding transcription switches the function of a Polycomb/Trithorax response element. Nat Genet. 2014;46:973-981 pubmed 出版商
Alfonso Parra C, Avila F, Deewatthanawong P, Sirot L, Wolfner M, Harrington L. Synthesis, depletion and cell-type expression of a protein from the male accessory glands of the dengue vector mosquito Aedes aegypti. J Insect Physiol. 2014;70:117-24 pubmed 出版商
Tam J, Seah C, Pasternak S. The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid. Mol Brain. 2014;7:54 pubmed 出版商
Marín T, Contreras P, Castro J, Chamorro D, Balboa E, Bosch Morató M, et al. Vitamin E dietary supplementation improves neurological symptoms and decreases c-Abl/p73 activation in Niemann-Pick C mice. Nutrients. 2014;6:3000-17 pubmed 出版商
Calo S, Shertz Wall C, Lee S, Bastidas R, Nicolas F, Granek J, et al. Antifungal drug resistance evoked via RNAi-dependent epimutations. Nature. 2014;513:555-8 pubmed 出版商
Wolfe A, Singh K, Zhong Y, Drewe P, Rajasekhar V, Sanghvi V, et al. RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer. Nature. 2014;513:65-70 pubmed 出版商
Fang D, He K, Wang N, Sang Z, Qiu X, Xu G, et al. NEDD4 ubiquitinates TRAF3 to promote CD40-mediated AKT activation. Nat Commun. 2014;5:4513 pubmed 出版商
Mukherjee K, Slawson J, Christmann B, Griffith L. Neuron-specific protein interactions of Drosophila CASK-? are revealed by mass spectrometry. Front Mol Neurosci. 2014;7:58 pubmed 出版商
Tsai H, Li Y, Hsieh W, Lin M, Ahn J, Wu S. HUA ENHANCER1 is involved in posttranscriptional regulation of positive and negative regulators in Arabidopsis photomorphogenesis. Plant Cell. 2014;26:2858-72 pubmed 出版商
Ivanauskiene K, Delbarre E, McGhie J, Küntziger T, Wong L, Collas P. The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity. Genome Res. 2014;24:1584-94 pubmed 出版商
Graves J, Kordich J, Huang T, Piasecki J, Bush T, Sullivan T, et al. Apo2L/TRAIL and the death receptor 5 agonist antibody AMG 655 cooperate to promote receptor clustering and antitumor activity. Cancer Cell. 2014;26:177-89 pubmed 出版商
Ediger B, Du A, Liu J, Hunter C, Walp E, Schug J, et al. Islet-1 Is essential for pancreatic ?-cell function. Diabetes. 2014;63:4206-17 pubmed 出版商
Rowlands D, Nelson A, Phillips S, Faulkner J, Clarke J, Burd N, et al. Protein-leucine fed dose effects on muscle protein synthesis after endurance exercise. Med Sci Sports Exerc. 2015;47:547-55 pubmed 出版商
Durzynska J, Barton E. IGF expression in HPV-related and HPV-unrelated human cancer cells. Oncol Rep. 2014;32:893-900 pubmed 出版商
Rajabi H, Takahashi C, Ewen M. Retinoblastoma protein and MyoD function together to effect the repression of Fra-1 and in turn cyclin D1 during terminal cell cycle arrest associated with myogenesis. J Biol Chem. 2014;289:23417-27 pubmed 出版商
Huang Z, Ruan H, Xian L, Chen W, Jiang S, Song A, et al. The stem cell factor/Kit signalling pathway regulates mitochondrial function and energy expenditure. Nat Commun. 2014;5:4282 pubmed 出版商
Machicoane M, de Frutos C, Fink J, Rocancourt M, Lombardi Y, Garel S, et al. SLK-dependent activation of ERMs controls LGN-NuMA localization and spindle orientation. J Cell Biol. 2014;205:791-9 pubmed 出版商
Marcelli F, Boisset G, Schorderet D. A dimerized HMX1 inhibits EPHA6/epha4b in mouse and zebrafish retinas. PLoS ONE. 2014;9:e100096 pubmed 出版商
Guo S, Cheng X, Lim J, Liu Y, Kao H. Control of antioxidative response by the tumor suppressor protein PML through regulating Nrf2 activity. Mol Biol Cell. 2014;25:2485-98 pubmed 出版商
Fadel H, Morrison J, Saenz D, Fuchs J, Kvaratskhelia M, Ekker S, et al. TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism. J Virol. 2014;88:9704-17 pubmed 出版商
Glotfelty L, Zahs A, Iancu C, Shen L, Hecht G. Microtubules are required for efficient epithelial tight junction homeostasis and restoration. Am J Physiol Cell Physiol. 2014;307:C245-54 pubmed 出版商
Masciarelli S, Quaranta R, Iosue I, Colotti G, Padula F, Varchi G, et al. A small-molecule targeting the microRNA binding domain of argonaute 2 improves the retinoic acid differentiation response of the acute promyelocytic leukemia cell line NB4. ACS Chem Biol. 2014;9:1674-9 pubmed 出版商
Krisenko M, Cartagena A, Raman A, Geahlen R. Nanomechanical property maps of breast cancer cells as determined by multiharmonic atomic force microscopy reveal Syk-dependent changes in microtubule stability mediated by MAP1B. Biochemistry. 2015;54:60-8 pubmed 出版商
Lamparter C, Winn L. Tissue-specific effects of valproic acid on DNA repair genes and apoptosis in postimplantation mouse embryos. Toxicol Sci. 2014;141:59-67 pubmed 出版商
Lopez J, Lim R, Cruceanu C, Crapper L, Fasano C, Labonte B, et al. miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment. Nat Med. 2014;20:764-8 pubmed 出版商
Moorwood C, Barton E. Caspase-12 ablation preserves muscle function in the mdx mouse. Hum Mol Genet. 2014;23:5325-41 pubmed 出版商
Zahreddine H, Culjkovic Kraljacic B, Assouline S, Gendron P, Romeo A, Morris S, et al. The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation. Nature. 2014;511:90-3 pubmed 出版商
Rajgor D, Mellad J, Soong D, Rattner J, Fritzler M, Shanahan C. Mammalian microtubule P-body dynamics are mediated by nesprin-1. J Cell Biol. 2014;205:457-75 pubmed 出版商
Gupta A, Pirruccello M, Cheng F, Kang H, Fernandez T, Baskin J, et al. Rare deleterious mutations of the gene EFR3A in autism spectrum disorders. Mol Autism. 2014;5:31 pubmed 出版商
Olofsson A, Nygård Skalman L, Obi I, Lundmark R, Arnqvist A. Uptake of Helicobacter pylori vesicles is facilitated by clathrin-dependent and clathrin-independent endocytic pathways. MBio. 2014;5:e00979-14 pubmed 出版商
Carvalho S, Vítor A, Sridhara S, Martins F, Raposo A, Desterro J, et al. SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint. elife. 2014;3:e02482 pubmed 出版商
Rotter D, Grinsfelder D, Parra V, Pedrozo Z, Singh S, Sachan N, et al. Calcineurin and its regulator, RCAN1, confer time-of-day changes in susceptibility of the heart to ischemia/reperfusion. J Mol Cell Cardiol. 2014;74:103-11 pubmed 出版商
Müller S, Chen Y, Ginter T, Schafer C, Buchwald M, Schmitz L, et al. SIAH2 antagonizes TYK2-STAT3 signaling in lung carcinoma cells. Oncotarget. 2014;5:3184-96 pubmed
Vega Naredo I, Loureiro R, Mesquita K, Barbosa I, Tavares L, Branco A, et al. Mitochondrial metabolism directs stemness and differentiation in P19 embryonal carcinoma stem cells. Cell Death Differ. 2014;21:1560-74 pubmed 出版商
Jongjitwimol J, Feng M, Zhou L, Wilkinson O, Small L, Baldock R, et al. The S. pombe translation initiation factor eIF4G is Sumoylated and associates with the SUMO protease Ulp2. PLoS ONE. 2014;9:e94182 pubmed 出版商
White E, Schlackow M, Kamieniarz Gdula K, Proudfoot N, Gullerova M. Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA. Nat Struct Mol Biol. 2014;21:552-9 pubmed 出版商
Schumpert C, Handy I, Dudycha J, Patel R. Relationship between heat shock protein 70 expression and life span in Daphnia. Mech Ageing Dev. 2014;139:1-10 pubmed 出版商
Licht V, Noack K, Schlott B, Forster M, Schlenker Y, Licht A, et al. Caspase-3 and caspase-6 cleave STAT1 in leukemic cells. Oncotarget. 2014;5:2305-17 pubmed
Choi Y, Battelli C, Watson J, Liu J, Curtis J, Morse A, et al. Sublethal concentrations of 17-AAG suppress homologous recombination DNA repair and enhance sensitivity to carboplatin and olaparib in HR proficient ovarian cancer cells. Oncotarget. 2014;5:2678-87 pubmed
Veenendaal T, Jarvela T, Grieve A, van Es J, Linstedt A, Rabouille C. GRASP65 controls the cis Golgi integrity in vivo. Biol Open. 2014;3:431-43 pubmed 出版商
Huang P, Hsiao Y, Kao S, Chen C, Chen Y, Chiang C, et al. Adenosine A(2A) receptor up-regulates retinal wave frequency via starburst amacrine cells in the developing rat retina. PLoS ONE. 2014;9:e95090 pubmed 出版商
Pfisterer S, Bakula D, Frickey T, Cezanne A, Brigger D, Tschan M, et al. Lipid droplet and early autophagosomal membrane targeting of Atg2A and Atg14L in human tumor cells. J Lipid Res. 2014;55:1267-78 pubmed 出版商
Behrens A, Zierold C, Shi X, Ren Y, Koyano Nakagawa N, Garry D, et al. Sox7 is regulated by ETV2 during cardiovascular development. Stem Cells Dev. 2014;23:2004-13 pubmed 出版商
Golubeva A, Zhdanov A, Mallel G, Dinan T, Cryan J. The mouse cyclophosphamide model of bladder pain syndrome: tissue characterization, immune profiling, and relationship to metabotropic glutamate receptors. Physiol Rep. 2014;2:e00260 pubmed 出版商
Harris D, Bandyopadhyay S, Maxwell T, Willard B, DiCorleto P. Tumor necrosis factor (TNF)-? induction of CXCL10 in endothelial cells requires protein arginine methyltransferase 5 (PRMT5)-mediated nuclear factor (NF)-?B p65 methylation. J Biol Chem. 2014;289:15328-39 pubmed 出版商
Naka K K, Vezyraki P, Kalaitzakis A, Zerikiotis S, Michalis L, Angelidis C. Hsp70 regulates the doxorubicin-mediated heart failure in Hsp70-transgenic mice. Cell Stress Chaperones. 2014;19:853-64 pubmed 出版商
Dogan I, Kawabata S, Bergbower E, Gills J, Ekmekci A, Wilson W, et al. SOX2 expression is an early event in a murine model of EGFR mutant lung cancer and promotes proliferation of a subset of EGFR mutant lung adenocarcinoma cell lines. Lung Cancer. 2014;85:1-6 pubmed 出版商
Kojima S, Borisy G. An image-based, dual fluorescence reporter assay to evaluate the efficacy of shRNA for gene silencing at the single-cell level. F1000Res. 2014;3:60 pubmed 出版商
Liu C, Lou W, Zhu Y, Nadiminty N, Schwartz C, Evans C, et al. Niclosamide inhibits androgen receptor variants expression and overcomes enzalutamide resistance in castration-resistant prostate cancer. Clin Cancer Res. 2014;20:3198-3210 pubmed 出版商
Aaltonen V, Kinnunen K, Jouhilahti E, Peltonen J, Nikinmaa M, Kaarniranta K, et al. Hypoxic conditions stimulate the release of B-type natriuretic peptide from human retinal pigment epithelium cell culture. Acta Ophthalmol. 2014;92:740-4 pubmed 出版商
Wu D, Chen L, Sun Q, Wu X, Jia S, Meng A. Uracil-DNA glycosylase is involved in DNA demethylation and required for embryonic development in the zebrafish embryo. J Biol Chem. 2014;289:15463-73 pubmed 出版商
Tahmasebi S, Ghorbani M, Savage P, Gocevski G, Yang X. The SUMO conjugating enzyme Ubc9 is required for inducing and maintaining stem cell pluripotency. Stem Cells. 2014;32:1012-20 pubmed 出版商
Barton L, Wilmington S, Martin M, Skopec H, Lovander K, Pinto B, et al. Unique and shared functions of nuclear lamina LEM domain proteins in Drosophila. Genetics. 2014;197:653-65 pubmed 出版商
Min J, Vonesch C, Kirshner H, Carlini L, Olivier N, Holden S, et al. FALCON: fast and unbiased reconstruction of high-density super-resolution microscopy data. Sci Rep. 2014;4:4577 pubmed 出版商
Tapia Alveal C, Lin S, Yeoh A, Jabado O, O Connell M. H2A.Z-dependent regulation of cohesin dynamics on chromosome arms. Mol Cell Biol. 2014;34:2092-104 pubmed 出版商
Kokkola T, Suuronen T, Molnár F, Määttä J, Salminen A, Jarho E, et al. AROS has a context-dependent effect on SIRT1. FEBS Lett. 2014;588:1523-8 pubmed 出版商
Walker S, Liu S, Xiang M, Nicolais M, Hatzi K, Giannopoulou E, et al. The transcriptional modulator BCL6 as a molecular target for breast cancer therapy. Oncogene. 2015;34:1073-82 pubmed 出版商
Marín Aguilera M, Codony Servat J, Reig O, Lozano J, Fernandez P, Pereira M, et al. Epithelial-to-mesenchymal transition mediates docetaxel resistance and high risk of relapse in prostate cancer. Mol Cancer Ther. 2014;13:1270-84 pubmed 出版商
Cai K, Mulatz K, Ard R, Nguyen T, Gee S. Increased diacylglycerol kinase ? expression in human metastatic colon cancer cells augments Rho GTPase activity and contributes to enhanced invasion. BMC Cancer. 2014;14:208 pubmed 出版商
Macvicar T, Lane J. Impaired OMA1-dependent cleavage of OPA1 and reduced DRP1 fission activity combine to prevent mitophagy in cells that are dependent on oxidative phosphorylation. J Cell Sci. 2014;127:2313-25 pubmed 出版商
Aune S, Herr D, Mani S, Menick D. Selective inhibition of class I but not class IIb histone deacetylases exerts cardiac protection from ischemia reperfusion. J Mol Cell Cardiol. 2014;72:138-45 pubmed 出版商
Vangala J, Dudem S, Jain N, Kalivendi S. Regulation of PSMB5 protein and ? subunits of mammalian proteasome by constitutively activated signal transducer and activator of transcription 3 (STAT3): potential role in bortezomib-mediated anticancer therapy. J Biol Chem. 2014;289:12612-22 pubmed 出版商
Chakraborty A, Prasanth K, Prasanth S. Dynamic phosphorylation of HP1? regulates mitotic progression in human cells. Nat Commun. 2014;5:3445 pubmed 出版商
Gressette M, Verillaud B, Jimenez Pailhes A, Lelièvre H, Lo K, Ferrand F, et al. Treatment of nasopharyngeal carcinoma cells with the histone-deacetylase inhibitor abexinostat: cooperative effects with cis-platin and radiotherapy on patient-derived xenografts. PLoS ONE. 2014;9:e91325 pubmed 出版商
Le Gal L, Alonso F, Wagner C, Germain S, Nardelli Haefliger D, Meda P, et al. Restoration of connexin 40 (Cx40) in Renin-producing cells reduces the hypertension of Cx40 null mice. Hypertension. 2014;63:1198-204 pubmed 出版商
Keller D, Orpinell M, Olivier N, Wachsmuth M, Mahen R, Wyss R, et al. Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells. J Cell Biol. 2014;204:697-712 pubmed 出版商
Avery Cooper G, Doerr M, Gilbert R, Youssef M, Richard A, Huether P, et al. Par6 is an essential mediator of apoptotic response to transforming growth factor beta in NMuMG immortalized mammary cells. Cancer Cell Int. 2014;14:19 pubmed 出版商
Nobusue H, Onishi N, Shimizu T, Sugihara E, Oki Y, Sumikawa Y, et al. Regulation of MKL1 via actin cytoskeleton dynamics drives adipocyte differentiation. Nat Commun. 2014;5:3368 pubmed 出版商
Okada N, Lin C, Ribeiro M, Biton A, Lai G, He X, et al. A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression. Genes Dev. 2014;28:438-50 pubmed 出版商
Joy M, Vollmer L, HULKOWER K, Stern A, Peterson C, Boltz R, et al. A high-content, multiplexed screen in human breast cancer cells identifies profilin-1 inducers with anti-migratory activities. PLoS ONE. 2014;9:e88350 pubmed 出版商
LaFlamme B, Avila F, Michalski K, Wolfner M. A Drosophila protease cascade member, seminal metalloprotease-1, is activated stepwise by male factors and requires female factors for full activity. Genetics. 2014;196:1117-29 pubmed 出版商
Ribarska T, Goering W, Droop J, Bastian K, Ingenwerth M, Schulz W. Deregulation of an imprinted gene network in prostate cancer. Epigenetics. 2014;9:704-17 pubmed 出版商
Piao H, Yuan Y, Wang M, Sun Y, Liang H, Ma L. ?-catenin acts as a tumour suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-?B signalling. Nat Cell Biol. 2014;16:245-54 pubmed 出版商
Tonazzini I, Pellegrini M, Pellegrino M, Cecchini M. Interaction of leech neurons with topographical gratings: comparison with rodent and human neuronal lines and primary cells. Interface Focus. 2014;4:20130047 pubmed 出版商
Gray C, Remouchamps C, McCorkell K, Solt L, Dejardin E, Orange J, et al. Noncanonical NF-?B signaling is limited by classical NF-?B activity. Sci Signal. 2014;7:ra13 pubmed 出版商
Schulze N, Graessl M, Blancke Soares A, Geyer M, Dehmelt L, Nalbant P. FHOD1 regulates stress fiber organization by controlling the dynamics of transverse arcs and dorsal fibers. J Cell Sci. 2014;127:1379-93 pubmed 出版商
Xiang M, Birkbak N, Vafaizadeh V, Walker S, Yeh J, Liu S, et al. STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-?B to IL-6 signaling axis and STAT3-driven cancer phenotypes. Sci Signal. 2014;7:ra11 pubmed 出版商
Lin L, Chen K, Abdel Khalek W, Ward J, Yang H, Chabi B, et al. Regulation of skeletal muscle oxidative capacity and muscle mass by SIRT3. PLoS ONE. 2014;9:e85636 pubmed 出版商
Eritja N, Domingo M, Dosil M, Mirantes C, Santacana M, Valls J, et al. Combinatorial therapy using dovitinib and ICI182.780 (fulvestrant) blocks tumoral activity of endometrial cancer cells. Mol Cancer Ther. 2014;13:776-87 pubmed 出版商
Faggi F, Mitola S, Sorci G, Riuzzi F, Donato R, Codenotti S, et al. Phosphocaveolin-1 enforces tumor growth and chemoresistance in rhabdomyosarcoma. PLoS ONE. 2014;9:e84618 pubmed 出版商
Parmar M, Jaumotte J, Wyrostek S, Zigmond M, Cavanaugh J. Role of ERK1, 2, and 5 in dopamine neuron survival during aging. Neurobiol Aging. 2014;35:669-79 pubmed 出版商
Rigano L, Dowd G, Wang Y, Ireton K. Listeria monocytogenes antagonizes the human GTPase Cdc42 to promote bacterial spread. Cell Microbiol. 2014;16:1068-79 pubmed 出版商
Saborowski M, Saborowski A, Morris J, Bosbach B, Dow L, Pelletier J, et al. A modular and flexible ESC-based mouse model of pancreatic cancer. Genes Dev. 2014;28:85-97 pubmed 出版商
Qu S, Wang K, Xue H, Wang Y, Wu R, Liu C, et al. Enhanced anticancer activity of a combination of docetaxel and Aneustat (OMN54) in a patient-derived, advanced prostate cancer tissue xenograft model. Mol Oncol. 2014;8:311-22 pubmed 出版商
Parrish J, Sechler M, Winn R, Jedlicka P. The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma. Oncogene. 2015;34:257-62 pubmed 出版商
Lim R, Anand A, Nishimiya Fujisawa C, Kobayashi S, Kai T. Analysis of Hydra PIWI proteins and piRNAs uncover early evolutionary origins of the piRNA pathway. Dev Biol. 2014;386:237-51 pubmed 出版商
Long J, Ray B, Lahiri D. MicroRNA-339-5p down-regulates protein expression of ?-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects. J Biol Chem. 2014;289:5184-98 pubmed 出版商
Zou Y, Zwolanek D, Izu Y, Gandhy S, Schreiber G, Brockmann K, et al. Recessive and dominant mutations in COL12A1 cause a novel EDS/myopathy overlap syndrome in humans and mice. Hum Mol Genet. 2014;23:2339-52 pubmed 出版商
Panda D, Rose P, Hanna S, Gold B, Hopkins K, Lyde R, et al. Genome-wide RNAi screen identifies SEC61A and VCP as conserved regulators of Sindbis virus entry. Cell Rep. 2013;5:1737-48 pubmed 出版商
Bachmann V, Bister K, Stefan E. Interplay of PKA and Rac: fine-tuning of Rac localization and signaling. Small Gtpases. 2013;4:247-51 pubmed 出版商
De Leon Vazquez E, Juillard F, Rosner B, Kaye K. A short sequence immediately upstream of the internal repeat elements is critical for KSHV LANA mediated DNA replication and impacts episome persistence. Virology. 2014;448:344-55 pubmed 出版商
Liu C, Zhu Y, Lou W, Cui Y, Evans C, Gao A. Inhibition of constitutively active Stat3 reverses enzalutamide resistance in LNCaP derivative prostate cancer cells. Prostate. 2014;74:201-9 pubmed 出版商
Nakayama A, Nakayama M, Turner C, Höing S, Lepore J, Adams R. Ephrin-B2 controls PDGFR? internalization and signaling. Genes Dev. 2013;27:2576-89 pubmed 出版商
Goitre L, De Luca E, Braggion S, Trapani E, Guglielmotto M, Biasi F, et al. KRIT1 loss of function causes a ROS-dependent upregulation of c-Jun. Free Radic Biol Med. 2014;68:134-47 pubmed 出版商
Okuda H, Ohdan H, Nakayama M, Koseki H, Nakagawa T, Ito T. The USP21 short variant (USP21SV) lacking NES, located mostly in the nucleus in vivo, activates transcription by deubiquitylating ubH2A in vitro. PLoS ONE. 2013;8:e79813 pubmed 出版商
Sakakibara N, Chen D, Jang M, Kang D, Luecke H, Wu S, et al. Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA. PLoS Pathog. 2013;9:e1003777 pubmed 出版商
Beitnere U, van Groen T, Kumar A, Jansone B, Klusa V, Kadish I. Mildronate improves cognition and reduces amyloid-? pathology in transgenic Alzheimer's disease mice. J Neurosci Res. 2014;92:338-46 pubmed 出版商
Ijiri T, Vadnais M, Huang A, Lin A, Levin L, Buck J, et al. Thiol changes during epididymal maturation: a link to flagellar angulation in mouse spermatozoa?. Andrology. 2014;2:65-75 pubmed 出版商
Kubo T, Yanagisawa H, Liu Z, Shibuya R, Hirono M, Kamiya R. A conserved flagella-associated protein in Chlamydomonas, FAP234, is essential for axonemal localization of tubulin polyglutamylase TTLL9. Mol Biol Cell. 2014;25:107-17 pubmed 出版商
Marzinke M, Mavencamp T, Duratinsky J, Clagett Dame M. 14-3-3? and NAV2 interact to regulate neurite outgrowth and axon elongation. Arch Biochem Biophys. 2013;540:94-100 pubmed 出版商
Castelli M, Boca M, Chiaravalli M, Ramalingam H, Rowe I, Distefano G, et al. Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis. Nat Commun. 2013;4:2658 pubmed 出版商
Geiling B, Vandal G, Posner A, de Bruyns A, Dutchak K, Garnett S, et al. A modular lentiviral and retroviral construction system to rapidly generate vectors for gene expression and gene knockdown in vitro and in vivo. PLoS ONE. 2013;8:e76279 pubmed 出版商
Ji X, Wu Y, Yan J, Mehrens J, Yang H, Delucia M, et al. Mechanism of allosteric activation of SAMHD1 by dGTP. Nat Struct Mol Biol. 2013;20:1304-9 pubmed 出版商
Wang Y, Feng Y, Fu Q, Li L. Panax notoginsenoside Rb1 ameliorates Alzheimer's disease by upregulating brain-derived neurotrophic factor and downregulating Tau protein expression. Exp Ther Med. 2013;6:826-830 pubmed
Falkenberg N, Anastasov N, Rappl K, Braselmann H, Auer G, Walch A, et al. MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion. Br J Cancer. 2013;109:2714-23 pubmed 出版商
O Uchi J, Jhun B, Hurst S, Bisetto S, Gross P, Chen M, et al. Overexpression of ryanodine receptor type 1 enhances mitochondrial fragmentation and Ca2+-induced ATP production in cardiac H9c2 myoblasts. Am J Physiol Heart Circ Physiol. 2013;305:H1736-51 pubmed 出版商
Horiuchi K, Kawamura T, Iwanari H, Ohashi R, Naito M, Kodama T, et al. Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle. J Biol Chem. 2013;288:33292-302 pubmed 出版商
Ferranti F, D Anselmi F, Caruso M, Lei V, Dinicola S, Pasqualato A, et al. TCam-2 seminoma cells exposed to egg-derived microenvironment modify their shape, adhesive pattern and migratory behaviour: a molecular and morphometric analysis. PLoS ONE. 2013;8:e76192 pubmed 出版商
Grabarz A, Guirouilh Barbat J, Barascu A, Pennarun G, Genet D, Rass E, et al. A role for BLM in double-strand break repair pathway choice: prevention of CtIP/Mre11-mediated alternative nonhomologous end-joining. Cell Rep. 2013;5:21-8 pubmed 出版商
Moshkin Y, Doyen C, Kan T, Chalkley G, Sap K, Bezstarosti K, et al. Histone chaperone NAP1 mediates sister chromatid resolution by counteracting protein phosphatase 2A. PLoS Genet. 2013;9:e1003719 pubmed 出版商
Matsubayashi M, Teramoto Kimata I, Uni S, Lillehoj H, Matsuda H, Furuya M, et al. Elongation factor-1? is a novel protein associated with host cell invasion and a potential protective antigen of Cryptosporidium parvum. J Biol Chem. 2013;288:34111-20 pubmed 出版商
Dubuis C, May L, Alonso F, Luca L, Mylonaki I, Meda P, et al. Atorvastatin-loaded hydrogel affects the smooth muscle cells of human veins. J Pharmacol Exp Ther. 2013;347:574-81 pubmed 出版商
Mallat Y, Tritsch E, Ladouce R, Winter D, Friguet B, Li Z, et al. Proteome modulation in H9c2 cardiac cells by microRNAs miR-378 and miR-378. Mol Cell Proteomics. 2014;13:18-29 pubmed 出版商
Goodfellow V, Loweth C, Ravula S, WIEMANN T, Nguyen T, Xu Y, et al. Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3. J Med Chem. 2013;56:8032-48 pubmed 出版商
Kalra R, Bapat S. Enhanced levels of double-strand DNA break repair proteins protect ovarian cancer cells against genotoxic stress-induced apoptosis. J Ovarian Res. 2013;6:66 pubmed 出版商
Saldana S, Lee H, Lowery F, Khotskaya Y, Xia W, Zhang C, et al. Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis. PLoS ONE. 2013;8:e73406 pubmed 出版商
Lorda Diez C, Montero J, Choe S, Garcia Porrero J, Hurle J. Ligand- and stage-dependent divergent functions of BMP signaling in the differentiation of embryonic skeletogenic progenitors in vitro. J Bone Miner Res. 2014;29:735-48 pubmed 出版商
Díaz Mendoza M, Lorda Diez C, Montero J, Garcia Porrero J, Hurle J. Interdigital cell death in the embryonic limb is associated with depletion of Reelin in the extracellular matrix. Cell Death Dis. 2013;4:e800 pubmed 出版商
McLaughlin S, Olsen S, Dake B, De Raedt T, Lim E, Bronson R, et al. The RasGAP gene, RASAL2, is a tumor and metastasis suppressor. Cancer Cell. 2013;24:365-78 pubmed 出版商
Abrieux A, Debernard S, Maria A, Gaertner C, Anton S, Gadenne C, et al. Involvement of the G-protein-coupled dopamine/ecdysteroid receptor DopEcR in the behavioral response to sex pheromone in an insect. PLoS ONE. 2013;8:e72785 pubmed 出版商
Lu X, Goke J, Sachs F, Jacques P, Liang H, Feng B, et al. SON connects the splicing-regulatory network with pluripotency in human embryonic stem cells. Nat Cell Biol. 2013;15:1141-1152 pubmed 出版商
Zeng L, Wan Y, Li D, Wu J, Shao M, Chen J, et al. The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control. J Biol Chem. 2013;288:30087-93 pubmed 出版商
Patel P, Yan P, Seidler P, Patel H, Sun W, Yang C, et al. Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2. Nat Chem Biol. 2013;9:677-84 pubmed 出版商
Gamell C, Schofield A, Suryadinata R, Sarcevic B, Bernard O. LIMK2 mediates resistance to chemotherapeutic drugs in neuroblastoma cells through regulation of drug-induced cell cycle arrest. PLoS ONE. 2013;8:e72850 pubmed 出版商
Liu Y, Xie Q, Wang B, Shao J, Zhang T, Liu T, et al. Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics. Protein Cell. 2013;4:702-10 pubmed 出版商
Bueno M, Richard S. SUMOylation negatively modulates target gene occupancy of the KDM5B, a histone lysine demethylase. Epigenetics. 2013;8:1162-75 pubmed 出版商
Vafaie F, Yin H, O Neil C, Nong Z, Watson A, Arpino J, et al. Collagenase-resistant collagen promotes mouse aging and vascular cell senescence. Aging Cell. 2014;13:121-30 pubmed 出版商
Samsonov A, Zenser N, Zhang F, Zhang H, Fetter J, Malkov D. Tagging of genomic STAT3 and STAT1 with fluorescent proteins and insertion of a luciferase reporter in the cyclin D1 gene provides a modified A549 cell line to screen for selective STAT3 inhibitors. PLoS ONE. 2013;8:e68391 pubmed 出版商
O Farrell F, Wang S, Katheder N, Rusten T, Samakovlis C. Two-tiered control of epithelial growth and autophagy by the insulin receptor and the ret-like receptor, stitcher. PLoS Biol. 2013;11:e1001612 pubmed 出版商
Koziel K, Smigelskaite J, Drasche A, Enthammer M, Ashraf M, Khalid S, et al. RAF and antioxidants prevent cell death induction after growth factor abrogation through regulation of Bcl-2 proteins. Exp Cell Res. 2013;319:2728-38 pubmed 出版商
Lapierre L, De Magalhaes Filho C, McQuary P, Chu C, Visvikis O, Chang J, et al. The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans. Nat Commun. 2013;4:2267 pubmed 出版商
Oku Y, Huganir R. AGAP3 and Arf6 regulate trafficking of AMPA receptors and synaptic plasticity. J Neurosci. 2013;33:12586-98 pubmed 出版商
Zhdanov A, Waters A, Golubeva A, Dmitriev R, Papkovsky D. Availability of the key metabolic substrates dictates the respiratory response of cancer cells to the mitochondrial uncoupling. Biochim Biophys Acta. 2014;1837:51-62 pubmed 出版商
Murata H, Sakaguchi M, Kataoka K, Huh N. SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria. Mol Biol Cell. 2013;24:2772-84 pubmed 出版商
Olivier N, Keller D, GONCZY P, Manley S. Resolution doubling in 3D-STORM imaging through improved buffers. PLoS ONE. 2013;8:e69004 pubmed 出版商
Intawicha P, Wang S, Hsieh Y, Lo N, Lee K, Huang S, et al. Proteomic profiling of rabbit embryonic stem cells derived from parthenotes and fertilized embryos. PLoS ONE. 2013;8:e67772 pubmed 出版商
Herbomel G, Kloster Landsberg M, Folco E, Col E, Usson Y, Vourc h C, et al. Dynamics of the full length and mutated heat shock factor 1 in human cells. PLoS ONE. 2013;8:e67566 pubmed 出版商
Garrido Godino A, García López M, Navarro F. Correct assembly of RNA polymerase II depends on the foot domain and is required for multiple steps of transcription in Saccharomyces cerevisiae. Mol Cell Biol. 2013;33:3611-26 pubmed 出版商
Kim M, Park H, Park H, Ro S, Nam S, Reed J, et al. Drosophila Fip200 is an essential regulator of autophagy that attenuates both growth and aging. Autophagy. 2013;9:1201-13 pubmed 出版商
Lu J, Zavorotinskaya T, Dai Y, Niu X, Castillo J, Sim J, et al. Pim2 is required for maintaining multiple myeloma cell growth through modulating TSC2 phosphorylation. Blood. 2013;122:1610-20 pubmed 出版商
Kyrmizi I, Gresnigt M, Akoumianaki T, Samonis G, Sidiropoulos P, Boumpas D, et al. Corticosteroids block autophagy protein recruitment in Aspergillus fumigatus phagosomes via targeting dectin-1/Syk kinase signaling. J Immunol. 2013;191:1287-99 pubmed 出版商
Ivanov A, Pawlikowski J, Manoharan I, van Tuyn J, Nelson D, Rai T, et al. Lysosome-mediated processing of chromatin in senescence. J Cell Biol. 2013;202:129-43 pubmed 出版商
Elsum I, Martin C, Humbert P. Scribble regulates an EMT polarity pathway through modulation of MAPK-ERK signaling to mediate junction formation. J Cell Sci. 2013;126:3990-9 pubmed 出版商
Barton L, Pinto B, Wallrath L, Geyer P. The Drosophila nuclear lamina protein otefin is required for germline stem cell survival. Dev Cell. 2013;25:645-54 pubmed 出版商
Caron M, Morissette M, Thériault M, Nikota J, Stampfli M, Debigare R. Alterations in skeletal muscle cell homeostasis in a mouse model of cigarette smoke exposure. PLoS ONE. 2013;8:e66433 pubmed 出版商
Tummala R, Nadiminty N, Lou W, Zhu Y, Gandour Edwards R, Chen H, et al. Lin28 promotes growth of prostate cancer cells and activates the androgen receptor. Am J Pathol. 2013;183:288-95 pubmed 出版商
Sominsky L, Sobinoff A, Jobling M, Pye V, McLaughlin E, Hodgson D. Immune regulation of ovarian development: programming by neonatal immune challenge. Front Neurosci. 2013;7:100 pubmed 出版商
Elsum I, Humbert P. Localization, not important in all tumor-suppressing properties: a lesson learnt from scribble. Cells Tissues Organs. 2013;198:1-11 pubmed 出版商
Marker D, Tremblay M, Puccini J, Barbieri J, Gantz Marker M, Loweth C, et al. The new small-molecule mixed-lineage kinase 3 inhibitor URMC-099 is neuroprotective and anti-inflammatory in models of human immunodeficiency virus-associated neurocognitive disorders. J Neurosci. 2013;33:9998-10010 pubmed 出版商
Olivier N, Keller D, Rajan V, GONCZY P, Manley S. Simple buffers for 3D STORM microscopy. Biomed Opt Express. 2013;4:885-99 pubmed 出版商
Kalebic N, Sorrentino S, Perlas E, Bolasco G, Martínez C, Heppenstall P. αTAT1 is the major α-tubulin acetyltransferase in mice. Nat Commun. 2013;4:1962 pubmed 出版商
Kim G, Li L, Ghorbani M, You L, Yang X. Mice lacking α-tubulin acetyltransferase 1 are viable but display α-tubulin acetylation deficiency and dentate gyrus distortion. J Biol Chem. 2013;288:20334-50 pubmed 出版商
Yamazaki A, Nishizawa Y, Matsuura I, Hayashi F, Usukura J, Bondarenko V. Microtubule-associated protein tau in bovine retinal photoreceptor rod outer segments: comparison with brain tau. Biochim Biophys Acta. 2013;1832:1549-59 pubmed 出版商
Kuroshima S, Mecano R, Tanoue R, Koi K, Yamashita J. Distinctive tooth-extraction socket healing: bisphosphonate versus parathyroid hormone therapy. J Periodontol. 2014;85:24-33 pubmed 出版商
Gylfe A, Kondelin J, Turunen M, Ristolainen H, Katainen R, Pitkänen E, et al. Identification of candidate oncogenes in human colorectal cancers with microsatellite instability. Gastroenterology. 2013;145:540-3.e22 pubmed 出版商
Müller R, Jenny A, Stanley P. The EGF repeat-specific O-GlcNAc-transferase Eogt interacts with notch signaling and pyrimidine metabolism pathways in Drosophila. PLoS ONE. 2013;8:e62835 pubmed 出版商
Cartelli D, Casagrande F, Busceti C, Bucci D, Molinaro G, Traficante A, et al. Microtubule alterations occur early in experimental parkinsonism and the microtubule stabilizer epothilone D is neuroprotective. Sci Rep. 2013;3:1837 pubmed 出版商
Fleming J, Gable D, Samadzadeh Tarighat S, Cheng L, Yu L, Gillespie J, et al. Differential expression of miR-1, a putative tumor suppressing microRNA, in cancer resistant and cancer susceptible mice. Peerj. 2013;1:e68 pubmed 出版商
Nair S, Marlow F, ABRAMS E, KAPP L, Mullins M, Pelegri F. The chromosomal passenger protein birc5b organizes microfilaments and germ plasm in the zebrafish embryo. PLoS Genet. 2013;9:e1003448 pubmed 出版商
Han J, Back S, Hur J, Lin Y, Gildersleeve R, Shan J, et al. ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. Nat Cell Biol. 2013;15:481-90 pubmed 出版商
Zhou X, Gewurz B, Ritchie J, Takasaki K, Greenfeld H, Kieff E, et al. A Vibrio parahaemolyticus T3SS effector mediates pathogenesis by independently enabling intestinal colonization and inhibiting TAK1 activation. Cell Rep. 2013;3:1690-702 pubmed 出版商
Wu J, Chen C, Coumar M, Lin W, Chen Z, Hsu J, et al. Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules. Proc Natl Acad Sci U S A. 2013;110:E1779-87 pubmed 出版商
Kuchay S, Duan S, Schenkein E, Peschiaroli A, Saraf A, Florens L, et al. FBXL2- and PTPL1-mediated degradation of p110-free p85? regulatory subunit controls the PI(3)K signalling cascade. Nat Cell Biol. 2013;15:472-80 pubmed 出版商
Perez Lozano M, Sandoval P, Rynne Vidal A, Aguilera A, Jiménez Heffernan J, Albar Vizcaino P, et al. Functional relevance of the switch of VEGF receptors/co-receptors during peritoneal dialysis-induced mesothelial to mesenchymal transition. PLoS ONE. 2013;8:e60776 pubmed 出版商
Ludyga N, Englert S, Pflieger K, Rauser S, Braselmann H, Walch A, et al. The impact of cysteine-rich intestinal protein 1 (CRIP1) in human breast cancer. Mol Cancer. 2013;12:28 pubmed 出版商
Zoltowska K, Webster R, Finlayson S, Maxwell S, Cossins J, Müller J, et al. Mutations in GFPT1 that underlie limb-girdle congenital myasthenic syndrome result in reduced cell-surface expression of muscle AChR. Hum Mol Genet. 2013;22:2905-13 pubmed 出版商
Greussing R, Hackl M, Charoentong P, Pauck A, Monteforte R, Cavinato M, et al. Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts. BMC Genomics. 2013;14:224 pubmed 出版商
Nussbaum Krammer C, Park K, Li L, Melki R, Morimoto R. Spreading of a prion domain from cell-to-cell by vesicular transport in Caenorhabditis elegans. PLoS Genet. 2013;9:e1003351 pubmed 出版商
Moore H, Bai B, Matilainen O, Colis L, Peltonen K, Laiho M. Proteasome activity influences UV-mediated subnuclear localization changes of NPM. PLoS ONE. 2013;8:e59096 pubmed 出版商
Fujii W, Kano K, Sugiura K, Naito K. Repeatable construction method for engineered zinc finger nuclease based on overlap extension PCR and TA-cloning. PLoS ONE. 2013;8:e59801 pubmed 出版商
Posimo J, Titler A, Choi H, Unnithan A, Leak R. Neocortex and allocortex respond differentially to cellular stress in vitro and aging in vivo. PLoS ONE. 2013;8:e58596 pubmed 出版商
Rowe I, Chiaravalli M, Mannella V, Ulisse V, Quilici G, Pema M, et al. Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy. Nat Med. 2013;19:488-93 pubmed 出版商
Moiseeva O, Deschênes Simard X, St Germain E, Igelmann S, Huot G, Cadar A, et al. Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-?B activation. Aging Cell. 2013;12:489-98 pubmed 出版商
Lecland N, Debec A, Delmas A, Moutinho Pereira S, Malmanche N, Bouissou A, et al. Establishment and mitotic characterization of new Drosophila acentriolar cell lines from DSas-4 mutant. Biol Open. 2013;2:314-23 pubmed 出版商
Uekita T, Fujii S, Miyazawa Y, Hashiguchi A, Abe H, Sakamoto M, et al. Suppression of autophagy by CUB domain-containing protein 1 signaling is essential for anchorage-independent survival of lung cancer cells. Cancer Sci. 2013;104:865-70 pubmed 出版商
Betin V, Singleton B, Parsons S, Anstee D, Lane J. Autophagy facilitates organelle clearance during differentiation of human erythroblasts: evidence for a role for ATG4 paralogs during autophagosome maturation. Autophagy. 2013;9:881-93 pubmed 出版商
Lemons M. Characterizing Mystery Cell Lines: Student-driven Research Projects in an Undergraduate Neuroscience Laboratory Course. J Undergrad Neurosci Educ. 2012;10:A96-A104 pubmed
Kim N, Tresse E, Kolaitis R, Molliex A, Thomas R, Alami N, et al. VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations. Neuron. 2013;78:65-80 pubmed 出版商
Li J, D Angiolella V, Seeley E, Kim S, Kobayashi T, Fu W, et al. USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110. Nature. 2013;495:255-9 pubmed 出版商
Han G, Bian L, Li F, Cotrim A, Wang D, Lu J, et al. Preventive and therapeutic effects of Smad7 on radiation-induced oral mucositis. Nat Med. 2013;19:421-8 pubmed 出版商
Huang L, Jin J, Deighan P, Kiner E, McReynolds L, Lieberman J. Efficient and specific gene knockdown by small interfering RNAs produced in bacteria. Nat Biotechnol. 2013;31:350-6 pubmed 出版商
Don Salu Hewage A, Chan S, McAndrews K, Chetram M, Dawson M, Bethea D, et al. Cysteine (C)-x-C receptor 4 undergoes transportin 1-dependent nuclear localization and remains functional at the nucleus of metastatic prostate cancer cells. PLoS ONE. 2013;8:e57194 pubmed 出版商
Fu J, Zhang Q, Woods C, Zheng H, Yang B, Qu W, et al. Divergent effects of sulforaphane on basal and glucose-stimulated insulin secretion in ?-cells: role of reactive oxygen species and induction of endogenous antioxidants. Pharm Res. 2013;30:2248-59 pubmed 出版商
Sunami Y, Araki M, Hironaka Y, Morishita S, Kobayashi M, Liew E, et al. Inhibition of the NAD-dependent protein deacetylase SIRT2 induces granulocytic differentiation in human leukemia cells. PLoS ONE. 2013;8:e57633 pubmed 出版商
Mirón García M, Garrido Godino A, García Molinero V, Hernández Torres F, Rodriguez Navarro S, Navarro F. The prefoldin bud27 mediates the assembly of the eukaryotic RNA polymerases in an rpb5-dependent manner. PLoS Genet. 2013;9:e1003297 pubmed 出版商
Cogli L, Progida C, Bramato R, Bucci C. Vimentin phosphorylation and assembly are regulated by the small GTPase Rab7a. Biochim Biophys Acta. 2013;1833:1283-93 pubmed 出版商
Randazzo D, Giacomello E, Lorenzini S, Rossi D, Pierantozzi E, Blaauw B, et al. Obscurin is required for ankyrinB-dependent dystrophin localization and sarcolemma integrity. J Cell Biol. 2013;200:523-36 pubmed 出版商
Chang Y, Wang S, Wang Y, Zhou J, Li W, Wang N, et al. ECHS1 interacts with STAT3 and negatively regulates STAT3 signaling. FEBS Lett. 2013;587:607-13 pubmed 出版商
Absood A, Gandomani B, Zaki A, Nasta V, Michail A, Habib P, et al. Insulin therapy for pre-hyperglycemic beta-cell endoplasmic reticulum crowding. PLoS ONE. 2013;8:e54351 pubmed 出版商
Durzynska J, Philippou A, Brisson B, Nguyen McCarty M, Barton E. The pro-forms of insulin-like growth factor I (IGF-I) are predominant in skeletal muscle and alter IGF-I receptor activation. Endocrinology. 2013;154:1215-24 pubmed 出版商
Boittin F, Alonso F, Le Gal L, Allagnat F, Beny J, Haefliger J. Connexins and M3 muscarinic receptors contribute to heterogeneous Ca(2+) signaling in mouse aortic endothelium. Cell Physiol Biochem. 2013;31:166-78 pubmed 出版商
Dynoodt P, Speeckaert R, De Wever O, Chevolet I, Brochez L, Lambert J, et al. miR-145 overexpression suppresses the migration and invasion of metastatic melanoma cells. Int J Oncol. 2013;42:1443-51 pubmed 出版商
Liang X, Hart C, Crooke S. Transfection of siRNAs can alter miRNA levels and trigger non-specific protein degradation in mammalian cells. Biochim Biophys Acta. 2013;1829:455-68 pubmed 出版商
Berti M, Ray Chaudhuri A, Thangavel S, Gomathinayagam S, Kenig S, Vujanovic M, et al. Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition. Nat Struct Mol Biol. 2013;20:347-54 pubmed 出版商
Wu Y, Zhang Y, Wang M, Li Q, Qu Z, Shi V, et al. Downregulation of HER3 by a novel antisense oligonucleotide, EZN-3920, improves the antitumor activity of EGFR and HER2 tyrosine kinase inhibitors in animal models. Mol Cancer Ther. 2013;12:427-37 pubmed 出版商
Hendrix A, Sormunen R, Westbroek W, Lambein K, Denys H, Sys G, et al. Vacuolar H+ ATPase expression and activity is required for Rab27B-dependent invasive growth and metastasis of breast cancer. Int J Cancer. 2013;133:843-54 pubmed 出版商
Ludyga N, Anastasov N, Rosemann M, Seiler J, Lohmann N, Braselmann H, et al. Effects of simultaneous knockdown of HER2 and PTK6 on malignancy and tumor progression in human breast cancer cells. Mol Cancer Res. 2013;11:381-92 pubmed 出版商
Valencia R, Walko G, Janda L, Novacek J, Mihailovska E, Reipert S, et al. Intermediate filament-associated cytolinker plectin 1c destabilizes microtubules in keratinocytes. Mol Biol Cell. 2013;24:768-84 pubmed 出版商
Kirchner P, Bug M, Meyer H. Ubiquitination of the N-terminal region of caveolin-1 regulates endosomal sorting by the VCP/p97 AAA-ATPase. J Biol Chem. 2013;288:7363-72 pubmed 出版商
Grau L, Luque Garcia J, Gonzalez Peramato P, Theodorescu D, Palou J, Fernández Gómez J, et al. A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness. PLoS ONE. 2013;8:e53328 pubmed 出版商
Herzog N, Hartkamp J, Verheugd P, Treude F, Forst A, Feijs K, et al. Caspase-dependent cleavage of the mono-ADP-ribosyltransferase ARTD10 interferes with its pro-apoptotic function. FEBS J. 2013;280:1330-43 pubmed 出版商
Hua H, Namdar M, Ganier O, Gregan J, Mechali M, Kearsey S. Sequential steps in DNA replication are inhibited to ensure reduction of ploidy in meiosis. Mol Biol Cell. 2013;24:578-87 pubmed 出版商
Heinnickel M, Alric J, Wittkopp T, Yang W, Catalanotti C, Dent R, et al. Novel thylakoid membrane GreenCut protein CPLD38 impacts accumulation of the cytochrome b6f complex and associated regulatory processes. J Biol Chem. 2013;288:7024-36 pubmed 出版商
Ornelas I, Silva T, Fragel Madeira L, Ventura A. Inhibition of PI3K/Akt pathway impairs G2/M transition of cell cycle in late developing progenitors of the avian embryo retina. PLoS ONE. 2013;8:e53517 pubmed 出版商
Vervoort S, Lourenço A, van Boxtel R, Coffer P. SOX4 mediates TGF-?-induced expression of mesenchymal markers during mammary cell epithelial to mesenchymal transition. PLoS ONE. 2013;8:e53238 pubmed 出版商
Wang L, Feng J, Da L, Li Y, Li Z, Zhao M. Adenovirus-mediated delivery of siRNA targeting TM4SF4 attenuated liver cancer cell growth in vitro and in vivo. Acta Biochim Biophys Sin (Shanghai). 2013;45:213-9 pubmed 出版商
Jackson T, Salmina K, Huna A, Inashkina I, Jankevics E, Riekstina U, et al. DNA damage causes TP53-dependent coupling of self-renewal and senescence pathways in embryonal carcinoma cells. Cell Cycle. 2013;12:430-41 pubmed 出版商
Wannenes F, Magni L, Bonini M, Dimauro I, Caporossi D, Moretti C, et al. In vitro effects of Beta-2 agonists on skeletal muscle differentiation, hypertrophy, and atrophy. World Allergy Organ J. 2012;5:66-72 pubmed 出版商
Kalebic N, Martínez C, Perlas E, Hublitz P, Bilbao Cortes D, Fiedorczuk K, et al. Tubulin acetyltransferase ?TAT1 destabilizes microtubules independently of its acetylation activity. Mol Cell Biol. 2013;33:1114-23 pubmed 出版商
Lee M, Roy M, Ong S, Mertins P, Villani A, Li W, et al. Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach. Nat Immunol. 2013;14:179-85 pubmed 出版商
Macurek L, Benada J, Müllers E, Halim V, Krejcikova K, Burdova K, et al. Downregulation of Wip1 phosphatase modulates the cellular threshold of DNA damage signaling in mitosis. Cell Cycle. 2013;12:251-62 pubmed 出版商
Piao X, Komazawa Sakon S, Nishina T, Koike M, Piao J, Ehlken H, et al. c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis. Sci Signal. 2012;5:ra93 pubmed 出版商
Dessalle K, Euthine V, Chanon S, Delarichaudy J, Fujii I, Rome S, et al. SREBP-1 transcription factors regulate skeletal muscle cell size by controlling protein synthesis through myogenic regulatory factors. PLoS ONE. 2012;7:e50878 pubmed 出版商
Kitamura K, Fujiwara H. The type-2 N-end rule peptide recognition activity of Ubr11 ubiquitin ligase is required for the expression of peptide transporters. FEBS Lett. 2013;587:214-9 pubmed 出版商
Buchwald M, Pietschmann K, Brand P, Gunther A, Mahajan N, Heinzel T, et al. SIAH ubiquitin ligases target the nonreceptor tyrosine kinase ACK1 for ubiquitinylation and proteasomal degradation. Oncogene. 2013;32:4913-20 pubmed 出版商
Cogli L, Progida C, Thomas C, Spencer Dene B, Donno C, Schiavo G, et al. Charcot-Marie-Tooth type 2B disease-causing RAB7A mutant proteins show altered interaction with the neuronal intermediate filament peripherin. Acta Neuropathol. 2013;125:257-72 pubmed 出版商
Xie Q, Liu Y, Shao J, Yang J, Liu T, Zhang T, et al. Male contraceptive Adjudin is a potential anti-cancer drug. Biochem Pharmacol. 2013;85:345-55 pubmed 出版商
Figueiredo M, Philip P, Stenberg P, Larsson J. HP1a recruitment to promoters is independent of H3K9 methylation in Drosophila melanogaster. PLoS Genet. 2012;8:e1003061 pubmed 出版商
Shimamura S, Sasaki K, Tanaka M. The Src substrate SKAP2 regulates actin assembly by interacting with WAVE2 and cortactin proteins. J Biol Chem. 2013;288:1171-83 pubmed 出版商
Kula A, Gharu L, Marcello A. HIV-1 pre-mRNA commitment to Rev mediated export through PSF and Matrin 3. Virology. 2013;435:329-40 pubmed 出版商
Yüce O, West S. Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response. Mol Cell Biol. 2013;33:406-17 pubmed 出版商
Ming X, Rajapakse A, Yepuri G, Xiong Y, Carvas J, Ruffieux J, et al. Arginase II Promotes Macrophage Inflammatory Responses Through Mitochondrial Reactive Oxygen Species, Contributing to Insulin Resistance and Atherogenesis. J Am Heart Assoc. 2012;1:e000992 pubmed 出版商
Loedige I, Gaidatzis D, Sack R, Meister G, Filipowicz W. The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function. Nucleic Acids Res. 2013;41:518-32 pubmed 出版商
Guastafierro T, Catizone A, Calabrese R, Zampieri M, Martella O, Bacalini M, et al. ADP-ribose polymer depletion leads to nuclear Ctcf re-localization and chromatin rearrangement(1). Biochem J. 2013;449:623-30 pubmed 出版商
Selvaraj B, Frank N, Bender F, Asan E, Sendtner M. Local axonal function of STAT3 rescues axon degeneration in the pmn model of motoneuron disease. J Cell Biol. 2012;199:437-51 pubmed 出版商
Gierl M, Gruhn W, von Seggern A, Maltry N, Niehrs C. GADD45G functions in male sex determination by promoting p38 signaling and Sry expression. Dev Cell. 2012;23:1032-42 pubmed 出版商
Liang C, Tao Y, Shen C, Tan Z, Xiong W, Mei L. Erbin is required for myelination in regenerated axons after injury. J Neurosci. 2012;32:15169-80 pubmed 出版商
Chiang C, Chen Y, Lu J, Hsiao Y, Chang C, Huang P, et al. Synaptotagmin I regulates patterned spontaneous activity in the developing rat retina via calcium binding to the C2AB domains. PLoS ONE. 2012;7:e47465 pubmed 出版商
Suijkerbuijk S, Vleugel M, Teixeira A, Kops G. Integration of kinase and phosphatase activities by BUBR1 ensures formation of stable kinetochore-microtubule attachments. Dev Cell. 2012;23:745-55 pubmed 出版商
Ricci G, Guglielmo M, Caruso M, Ferranti F, Canipari R, Galdieri M, et al. Hepatocyte growth factor is a mouse fetal Leydig cell terminal differentiation factor. Biol Reprod. 2012;87:146 pubmed 出版商
Stavik B, Skretting G, Olstad O, Sletten M, Dehli Vigeland M, Sandset P, et al. TFPI alpha and beta regulate mRNAs and microRNAs involved in cancer biology and in the immune system in breast cancer cells. PLoS ONE. 2012;7:e47184 pubmed 出版商
Tosoni K, Stobbart M, Cassidy D, Venerando A, Pagano M, Luz S, et al. CFTR mutations altering CFTR fragmentation. Biochem J. 2013;449:295-305 pubmed 出版商
Raghavan B, Martin S, Esser P, Goebeler M, Schmidt M. Metal allergens nickel and cobalt facilitate TLR4 homodimerization independently of MD2. EMBO Rep. 2012;13:1109-15 pubmed 出版商
Kim M, Kim S, Lim J, Lee C, Choi H, Woo C. Laminar flow activation of ERK5 protein in vascular endothelium leads to atheroprotective effect via NF-E2-related factor 2 (Nrf2) activation. J Biol Chem. 2012;287:40722-31 pubmed 出版商
Lin Y, Richards F, Krippendorff B, Bramhall J, Harrington J, Bapiro T, et al. Paclitaxel and CYC3, an aurora kinase A inhibitor, synergise in pancreatic cancer cells but not bone marrow precursor cells. Br J Cancer. 2012;107:1692-701 pubmed 出版商
Brisson B, Barton E. Insulin-like growth factor-I E-peptide activity is dependent on the IGF-I receptor. PLoS ONE. 2012;7:e45588 pubmed 出版商
Li H, Li J, Li Y, Singh P, Cao L, Xu L, et al. Sonic hedgehog promotes autophagy of vascular smooth muscle cells. Am J Physiol Heart Circ Physiol. 2012;303:H1319-31 pubmed 出版商
Willoughby L, Schlosser T, Manning S, Parisot J, Street I, Richardson H, et al. An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery. Dis Model Mech. 2013;6:521-9 pubmed 出版商
Ciarlo E, Massone S, Penna I, Nizzari M, Gigoni A, Dieci G, et al. An intronic ncRNA-dependent regulation of SORL1 expression affecting A? formation is upregulated in post-mortem Alzheimer's disease brain samples. Dis Model Mech. 2013;6:424-33 pubmed 出版商
Simmons M, Serra R, Hermance N, Kelliher M. NOTCH1 inhibition in vivo results in mammary tumor regression and reduced mammary tumorsphere-forming activity in vitro. Breast Cancer Res. 2012;14:R126 pubmed 出版商
Defour A, Dessalle K, Castro Perez A, Poyot T, Castells J, Gallot Y, et al. Sirtuin 1 regulates SREBP-1c expression in a LXR-dependent manner in skeletal muscle. PLoS ONE. 2012;7:e43490 pubmed 出版商
Wehler T, Hamdi S, Maderer A, Graf C, Gockel I, Schmidtmann I, et al. Single-agent therapy with sorafenib or 5-FU is equally effective in human colorectal cancer xenograft--no benefit of combination therapy. Int J Colorectal Dis. 2013;28:385-98 pubmed 出版商
Wang Z, Inuzuka H, Zhong J, Fukushima H, Wan L, Liu P, et al. DNA damage-induced activation of ATM promotes ?-TRCP-mediated Mdm2 ubiquitination and destruction. Oncotarget. 2012;3:1026-35 pubmed
Wiezlak M, Diring J, Abella J, Mouilleron S, Way M, McDonald N, et al. G-actin regulates the shuttling and PP1 binding of the RPEL protein Phactr1 to control actomyosin assembly. J Cell Sci. 2012;125:5860-72 pubmed 出版商
Guazzi P, Goitre L, Ferro E, Cutano V, Martino C, Trabalzini L, et al. Identification of the Kelch family protein Nd1-L as a novel molecular interactor of KRIT1. PLoS ONE. 2012;7:e44705 pubmed 出版商
Lin L, Huang H, Juan H. Revealing the molecular mechanism of gastric cancer marker annexin A4 in cancer cell proliferation using exon arrays. PLoS ONE. 2012;7:e44615 pubmed 出版商
Lee J, Lee J, Trembly J, Wilusz J, Tian B, Wilusz C. The PARN deadenylase targets a discrete set of mRNAs for decay and regulates cell motility in mouse myoblasts. PLoS Genet. 2012;8:e1002901 pubmed 出版商
Sadoul K, Wang J, Diagouraga B, Vitte A, Buchou T, Rossini T, et al. HDAC6 controls the kinetics of platelet activation. Blood. 2012;120:4215-8 pubmed 出版商
Lin L, Huang H, Ogihara S, Wang J, Wu M, McNeil P, et al. Helicobacter pylori disrupts host cell membranes, initiating a repair response and cell proliferation. Int J Mol Sci. 2012;13:10176-92 pubmed 出版商
Bui K, Yagi T, Yamamoto R, Kamiya R, Ishikawa T. Polarity and asymmetry in the arrangement of dynein and related structures in the Chlamydomonas axoneme. J Cell Biol. 2012;198:913-25 pubmed 出版商
Zhdanov A, Dmitriev R, Papkovsky D. Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling. Biosci Rep. 2012;32:587-95 pubmed 出版商
Pietschmann K, Bolck H, Buchwald M, Spielberg S, Polzer H, Spiekermann K, et al. Breakdown of the FLT3-ITD/STAT5 axis and synergistic apoptosis induction by the histone deacetylase inhibitor panobinostat and FLT3-specific inhibitors. Mol Cancer Ther. 2012;11:2373-83 pubmed 出版商
Yepuri G, Velagapudi S, Xiong Y, Rajapakse A, Montani J, Ming X, et al. Positive crosstalk between arginase-II and S6K1 in vascular endothelial inflammation and aging. Aging Cell. 2012;11:1005-16 pubmed 出版商
Luo X, Chen L, Dai J, Gao Y, Wang H, Wang N, et al. Gankyrin gene deletion followed by proteomic analysis: insight into the roles of Gankyrin in tumorigenesis and metastasis. BMC Med Genomics. 2012;5:36 pubmed 出版商
Peruquetti R, de Mateo S, Sassone Corsi P. Circadian proteins CLOCK and BMAL1 in the chromatoid body, a RNA processing granule of male germ cells. PLoS ONE. 2012;7:e42695 pubmed 出版商
Wang C, Ma N, Lin Y, Wu C, Hsiao M, Lu F, et al. A shRNA functional screen reveals Nme6 and Nme7 are crucial for embryonic stem cell renewal. Stem Cells. 2012;30:2199-211 pubmed 出版商
Jahn D, Schramm S, Schnolzer M, Heilmann C, de Koster C, Schütz W, et al. A truncated lamin A in the Lmna -/- mouse line: implications for the understanding of laminopathies. Nucleus. 2012;3:463-74 pubmed 出版商
Shaked H, Hofseth L, Chumanevich A, Chumanevich A, Wang J, Wang Y, et al. Chronic epithelial NF-?B activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation. Proc Natl Acad Sci U S A. 2012;109:14007-12 pubmed 出版商
Krauchunas A, Horner V, Wolfner M. Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. Dev Biol. 2012;370:125-34 pubmed 出版商
Bode N, Massey C, Gonzalez Alegre P. DYT1 knock-in mice are not sensitized against mitochondrial complex-II inhibition. PLoS ONE. 2012;7:e42644 pubmed 出版商
Oda M, Kanoh Y, Watanabe Y, Masai H. Regulation of DNA replication timing on human chromosome by a cell-type specific DNA binding protein SATB1. PLoS ONE. 2012;7:e42375 pubmed 出版商
Shih M, Cherng J. Protective effects of Chlorella-derived peptide against UVC-induced cytotoxicity through inhibition of caspase-3 activity and reduction of the expression of phosphorylated FADD and cleaved PARP-1 in skin fibroblasts. Molecules. 2012;17:9116-28 pubmed 出版商
Carlsten J, Szilagyi Z, Liu B, López M, Szászi E, Djupedal I, et al. Mediator promotes CENP-a incorporation at fission yeast centromeres. Mol Cell Biol. 2012;32:4035-43 pubmed 出版商
Izumi N, Helker C, Ehling M, Behrens A, Herzog W, Adams R. Fbxw7 controls angiogenesis by regulating endothelial Notch activity. PLoS ONE. 2012;7:e41116 pubmed 出版商
Patel R, Forinash K, Pireddu R, Sun Y, Sun N, Martin M, et al. RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer. Cancer Res. 2012;72:5025-34 pubmed 出版商
Cromer L, Heyman J, Touati S, Harashima H, Araou E, Girard C, et al. OSD1 promotes meiotic progression via APC/C inhibition and forms a regulatory network with TDM and CYCA1;2/TAM. PLoS Genet. 2012;8:e1002865 pubmed 出版商
Lamers F, Schild L, Koster J, Speleman F, Øra I, Westerhout E, et al. Identification of BIRC6 as a novel intervention target for neuroblastoma therapy. BMC Cancer. 2012;12:285 pubmed 出版商
Allen R, Marquart T, Albert C, Suchy F, Wang D, Ananthanarayanan M, et al. miR-33 controls the expression of biliary transporters, and mediates statin- and diet-induced hepatotoxicity. EMBO Mol Med. 2012;4:882-95 pubmed 出版商
Ardestani P, Liang F. Sub-cellular localization, expression and functions of Sirt6 during the cell cycle in HeLa cells. Nucleus. 2012;3:442-51 pubmed 出版商
Königsberger S, Prodöhl J, Stegner D, Weis V, Andreas M, Stehling M, et al. Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state. EMBO J. 2012;31:3363-74 pubmed 出版商
Grynberg M, Pierre A, Rey R, Leclerc A, Arouche N, Hesters L, et al. Differential regulation of ovarian anti-müllerian hormone (AMH) by estradiol through ?- and ?-estrogen receptors. J Clin Endocrinol Metab. 2012;97:E1649-57 pubmed 出版商
Hupalowska A, Pyrzynska B, Miaczynska M. APPL1 regulates basal NF-?B activity by stabilizing NIK. J Cell Sci. 2012;125:4090-102 pubmed 出版商
Shen M, Lin F, Zhang J, Tang Y, Chen W, Liu H. Involvement of the up-regulated FoxO1 expression in follicular granulosa cell apoptosis induced by oxidative stress. J Biol Chem. 2012;287:25727-40 pubmed 出版商
Hirata T, Watanabe M, Kaku H, Kobayashi Y, Yamada H, Sakaguchi M, et al. REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer. Int J Oncol. 2012;41:559-64 pubmed 出版商
O Donnell L, Rhodes D, Smith S, Merriner D, Clark B, Borg C, et al. An essential role for katanin p80 and microtubule severing in male gamete production. PLoS Genet. 2012;8:e1002698 pubmed 出版商
Halidi N, Alonso F, Burt J, Beny J, Haefliger J, Meister J. Intercellular calcium waves in primary cultured rat mesenteric smooth muscle cells are mediated by connexin43. Cell Commun Adhes. 2012;19:25-37 pubmed 出版商
Chiyoda T, Sugiyama N, Shimizu T, Naoe H, Kobayashi Y, Ishizawa J, et al. LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression. J Cell Biol. 2012;197:625-41 pubmed 出版商
Gannon H, Woda B, Jones S. ATM phosphorylation of Mdm2 Ser394 regulates the amplitude and duration of the DNA damage response in mice. Cancer Cell. 2012;21:668-79 pubmed 出版商
Guo L, Ghassemian M, Komives E, Russell P. Cadmium-induced proteome remodeling regulated by Spc1/Sty1 and Zip1 in fission yeast. Toxicol Sci. 2012;129:200-12 pubmed 出版商
Ginestier C, Monville F, Wicinski J, Cabaud O, Cervera N, Josselin E, et al. Mevalonate metabolism regulates Basal breast cancer stem cells and is a potential therapeutic target. Stem Cells. 2012;30:1327-37 pubmed 出版商
Galicia Vázquez G, Cencic R, Robert F, Agenor A, Pelletier J. A cellular response linking eIF4AI activity to eIF4AII transcription. RNA. 2012;18:1373-84 pubmed 出版商
Oikawa K, Tanaka M, Itoh S, Takanashi M, Ozaki T, Muragaki Y, et al. A novel oncogenic pathway by TLS-CHOP involving repression of MDA-7/IL-24 expression. Br J Cancer. 2012;106:1976-9 pubmed 出版商
Martino L, Masini M, Novelli M, Beffy P, Bugliani M, Marselli L, et al. Palmitate activates autophagy in INS-1E ?-cells and in isolated rat and human pancreatic islets. PLoS ONE. 2012;7:e36188 pubmed 出版商
Yang X, Wang W, Qin J, Wang M, Sharma H, Buolamwini J, et al. JKA97, a novel benzylidene analog of harmine, exerts anti-cancer effects by inducing G1 arrest, apoptosis, and p53-independent up-regulation of p21. PLoS ONE. 2012;7:e34303 pubmed 出版商
McIver S, Stanger S, Santarelli D, Roman S, Nixon B, McLaughlin E. A unique combination of male germ cell miRNAs coordinates gonocyte differentiation. PLoS ONE. 2012;7:e35553 pubmed 出版商
Yang H, Han Z, Cao Y, Fan D, Li H, Mo H, et al. A companion cell-dominant and developmentally regulated H3K4 demethylase controls flowering time in Arabidopsis via the repression of FLC expression. PLoS Genet. 2012;8:e1002664 pubmed 出版商
Kan A, van Erp S, Derijck A, de Wit M, Hessel E, O Duibhir E, et al. Genome-wide microRNA profiling of human temporal lobe epilepsy identifies modulators of the immune response. Cell Mol Life Sci. 2012;69:3127-45 pubmed 出版商
St Amour C, Sansó M, Bösken C, Lee K, Larochelle S, Zhang C, et al. Separate domains of fission yeast Cdk9 (P-TEFb) are required for capping enzyme recruitment and primed (Ser7-phosphorylated) Rpb1 carboxyl-terminal domain substrate recognition. Mol Cell Biol. 2012;32:2372-83 pubmed 出版商
Helsen C, Marchand A, Chaltin P, Munck S, Voet A, Verstuyf A, et al. Identification and characterization of MEL-3, a novel AR antagonist that suppresses prostate cancer cell growth. Mol Cancer Ther. 2012;11:1257-68 pubmed 出版商
Freund A, Laberge R, Demaria M, Campisi J. Lamin B1 loss is a senescence-associated biomarker. Mol Biol Cell. 2012;23:2066-75 pubmed 出版商
Place S, Smith B. Effects of seawater acidification on cell cycle control mechanisms in Strongylocentrotus purpuratus embryos. PLoS ONE. 2012;7:e34068 pubmed 出版商
Mungamuri S, Benson E, Wang S, Gu W, Lee S, Aaronson S. p53-mediated heterochromatin reorganization regulates its cell fate decisions. Nat Struct Mol Biol. 2012;19:478-84, S1 pubmed 出版商
Maheshwari S, Barbash D. Cis-by-Trans regulatory divergence causes the asymmetric lethal effects of an ancestral hybrid incompatibility gene. PLoS Genet. 2012;8:e1002597 pubmed 出版商
Lin L, Pang W, Chen K, Wang F, Gengler J, Sun Y, et al. Adipocyte expression of PU.1 transcription factor causes insulin resistance through upregulation of inflammatory cytokine gene expression and ROS production. Am J Physiol Endocrinol Metab. 2012;302:E1550-9 pubmed 出版商
Wei W, Ba Z, Gao M, Wu Y, Ma Y, Amiard S, et al. A role for small RNAs in DNA double-strand break repair. Cell. 2012;149:101-12 pubmed 出版商
Betin V, Macvicar T, Parsons S, Anstee D, Lane J. A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochondrial import and oxidative stress. Autophagy. 2012;8:664-76 pubmed 出版商
Cardeal L, Boccardo E, Termini L, Rabachini T, Andreoli M, Di Loreto C, et al. HPV16 oncoproteins induce MMPs/RECK-TIMP-2 imbalance in primary keratinocytes: possible implications in cervical carcinogenesis. PLoS ONE. 2012;7:e33585 pubmed 出版商
Zhou C, Licciulli S, Avila J, Cho M, Troutman S, Jiang P, et al. The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis. Oncogene. 2013;32:903-9 pubmed 出版商
Tanaka T, Iino M, Goto K. Knockdown of Sec6 improves cell-cell adhesion by increasing ?-E-catenin in oral cancer cells. FEBS Lett. 2012;586:924-33 pubmed 出版商
Klaić L, Morimoto R, Silverman R. Celastrol analogues as inducers of the heat shock response. Design and synthesis of affinity probes for the identification of protein targets. ACS Chem Biol. 2012;7:928-37 pubmed 出版商
Zhang L, McCabe T, Condra J, Ni Y, Peterson L, Wang W, et al. An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes. Int J Biol Sci. 2012;8:310-27 pubmed 出版商
Sun D, Tainsky M, Haddad R. Oncogene Mutation Survey in MPNST Cell Lines Enhances the Dominant Role of Hyperactive Ras in NF1 Associated Pro-Survival and Malignancy. Transl Oncogenomics. 2012;5:1-7 pubmed 出版商
Kalderon B, Azazmeh N, Azulay N, Vissler N, Valitsky M, Bar Tana J. Suppression of adipose lipolysis by long-chain fatty acid analogs. J Lipid Res. 2012;53:868-78 pubmed 出版商
Ryan J, Altamura S, Devitt E, Mullins S, Lawless M, Muckenthaler M, et al. Pegylated interferon-α induced hypoferremia is associated with the immediate response to treatment in hepatitis C. Hepatology. 2012;56:492-500 pubmed 出版商
Turlo K, Noel O, Vora R, Larussa M, Fassler R, Hall Glenn F, et al. An essential requirement for ?1 integrin in the assembly of extracellular matrix proteins within the vascular wall. Dev Biol. 2012;365:23-35 pubmed 出版商
Xu M, Takanashi M, Oikawa K, Nishi H, Isaka K, Yoshimoto T, et al. Identification of a novel role of Septin 10 in paclitaxel-resistance in cancers through a functional genomics screen. Cancer Sci. 2012;103:821-7 pubmed 出版商
Lu L, Zhou L, Chen E, Sun K, Jiang P, Wang L, et al. A Novel YY1-miR-1 regulatory circuit in skeletal myogenesis revealed by genome-wide prediction of YY1-miRNA network. PLoS ONE. 2012;7:e27596 pubmed 出版商
Long M, Huang S, Wu C, Shackleford G, Jong A. Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cells. J Biomed Sci. 2012;19:19 pubmed 出版商
Havens C, Shobnam N, Guarino E, Centore R, Zou L, Kearsey S, et al. Direct role for proliferating cell nuclear antigen in substrate recognition by the E3 ubiquitin ligase CRL4Cdt2. J Biol Chem. 2012;287:11410-21 pubmed 出版商
Bahtz R, Seidler J, Arnold M, Haselmann Weiss U, Antony C, Lehmann W, et al. GCP6 is a substrate of Plk4 and required for centriole duplication. J Cell Sci. 2012;125:486-96 pubmed 出版商
Urbé S, Liu H, Hayes S, Heride C, Rigden D, Clague M. Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions. Mol Biol Cell. 2012;23:1095-103 pubmed 出版商
Batailler B, Lemaitre T, Vilaine F, Sanchez C, Renard D, Cayla T, et al. Soluble and filamentous proteins in Arabidopsis sieve elements. Plant Cell Environ. 2012;35:1258-73 pubmed 出版商
Zaprazna K, Atchison M. YY1 controls immunoglobulin class switch recombination and nuclear activation-induced deaminase levels. Mol Cell Biol. 2012;32:1542-54 pubmed 出版商
Stauber R, Knauer S, Habtemichael N, Bier C, Unruhe B, Weisheit S, et al. A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer. Oncotarget. 2012;3:31-43 pubmed
Kyrou I, Papakostas J, Ioachim E, Koulouras V, Arnaoutoglou E, Angelidis C, et al. Early ischaemic preconditioning of spinal cord enhanced the binding profile of heat shock protein 70 with neurofilaments and promoted its nuclear translocation after thoraco-abdominal aortic occlusion in pigs. Eur J Vasc Endovasc Surg. 2012;43:408-14 pubmed 出版商
Velarde M, Flynn J, Day N, Melov S, Campisi J. Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin. Aging (Albany NY). 2012;4:3-12 pubmed
Tran H, Sanchez L, Brody D. Inhibition of JNK by a peptide inhibitor reduces traumatic brain injury-induced tauopathy in transgenic mice. J Neuropathol Exp Neurol. 2012;71:116-29 pubmed 出版商
Gao Y, Wei J, Han J, Wang X, Su G, Zhao Y, et al. The novel function of OCT4B isoform-265 in genotoxic stress. Stem Cells. 2012;30:665-72 pubmed 出版商
Silva M, Fox S, Beam M, Thakkar H, Amaral M, Morimoto R. A genetic screening strategy identifies novel regulators of the proteostasis network. PLoS Genet. 2011;7:e1002438 pubmed 出版商
Li Y, Wang L, Qiu J, Da L, Tiollais P, Li Z, et al. Human tetraspanin transmembrane 4 superfamily member 4 or intestinal and liver tetraspan membrane protein is overexpressed in hepatocellular carcinoma and accelerates tumor cell growth. Acta Biochim Biophys Sin (Shanghai). 2012;44:224-32 pubmed 出版商
Mitchell A, Leak R, Zigmond M, Cameron J, Mirnics K. Gene transcripts associated with BMI in the motor cortex and caudate nucleus of calorie restricted rhesus monkeys. Genomics. 2012;99:144-51 pubmed 出版商
Schnerch D, Follo M, Krohs J, Felthaus J, Engelhardt M, Wasch R. Monitoring APC/C activity in the presence of chromosomal misalignment in unperturbed cell populations. Cell Cycle. 2012;11:310-21 pubmed 出版商
Dialynas G, Flannery K, Zirbel L, Nagy P, Mathews K, Moore S, et al. LMNA variants cause cytoplasmic distribution of nuclear pore proteins in Drosophila and human muscle. Hum Mol Genet. 2012;21:1544-56 pubmed 出版商
Westendorp B, Mokry M, Groot Koerkamp M, Holstege F, Cuppen E, de Bruin A. E2F7 represses a network of oscillating cell cycle genes to control S-phase progression. Nucleic Acids Res. 2012;40:3511-23 pubmed 出版商
Lee M, Kim H, Kim T, Lee J. Gefitinib resistance of cancer cells correlated with TM4SF5-mediated epithelial-mesenchymal transition. Biochim Biophys Acta. 2012;1823:514-23 pubmed 出版商
Roggli E, Gattesco S, Pautz A, Regazzi R. Involvement of the RNA-binding protein ARE/poly(U)-binding factor 1 (AUF1) in the cytotoxic effects of proinflammatory cytokines on pancreatic beta cells. Diabetologia. 2012;55:1699-708 pubmed 出版商
Jiwani S, Wang Y, Dowd G, Gianfelice A, Pichestapong P, Gavicherla B, et al. Identification of components of the host type IA phosphoinositide 3-kinase pathway that promote internalization of Listeria monocytogenes. Infect Immun. 2012;80:1252-66 pubmed 出版商
Sharma S, Ma L, Bagui T, Forinash K, Pledger W. A p27Kip1 mutant that does not inhibit CDK activity promotes centrosome amplification and micronucleation. Oncogene. 2012;31:3989-98 pubmed 出版商
Gutierrez Uzquiza A, Arechederra M, Bragado P, Aguirre Ghiso J, Porras A. p38? mediates cell survival in response to oxidative stress via induction of antioxidant genes: effect on the p70S6K pathway. J Biol Chem. 2012;287:2632-42 pubmed 出版商
Coxon F. Fluorescence imaging of osteoclasts using confocal microscopy. Methods Mol Biol. 2012;816:401-24 pubmed 出版商
Tsai K, Thikmyanova N, Wojcechowskyj J, Delecluse H, Lieberman P. EBV tegument protein BNRF1 disrupts DAXX-ATRX to activate viral early gene transcription. PLoS Pathog. 2011;7:e1002376 pubmed 出版商
Xiang C, Baubet V, Pal S, Holderbaum L, Tatard V, Jiang P, et al. RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion. Cell Death Differ. 2012;19:692-702 pubmed 出版商
Sarantis K, Antoniou K, Matsokis N, Angelatou F. Exposure to novel environment is characterized by an interaction of D1/NMDA receptors underlined by phosphorylation of the NMDA and AMPA receptor subunits and activation of ERK1/2 signaling, leading to epigenetic changes and gene expression in rat hi. Neurochem Int. 2012;60:55-67 pubmed 出版商
Caron M, Charette S, Maltais F, Debigare R. Variability of protein level and phosphorylation status caused by biopsy protocol design in human skeletal muscle analyses. BMC Res Notes. 2011;4:488 pubmed 出版商
Hamada S, Satoh K, Fujibuchi W, Hirota M, Kanno A, Unno J, et al. MiR-126 acts as a tumor suppressor in pancreatic cancer cells via the regulation of ADAM9. Mol Cancer Res. 2012;10:3-10 pubmed 出版商
Merabova N, Kaminski R, Krynska B, Amini S, Khalili K, Darbinyan A. JCV agnoprotein-induced reduction in CXCL5/LIX secretion by oligodendrocytes is associated with activation of apoptotic signaling in neurons. J Cell Physiol. 2012;227:3119-27 pubmed 出版商
Zhang Y, Castaneda S, Dumble M, Wang M, Mileski M, Qu Z, et al. Reduced expression of the androgen receptor by third generation of antisense shows antitumor activity in models of prostate cancer. Mol Cancer Ther. 2011;10:2309-19 pubmed 出版商
Morioka M, Parameswaran H, Naruse K, Kondo M, Sokabe M, Hasegawa Y, et al. Microtubule dynamics regulate cyclic stretch-induced cell alignment in human airway smooth muscle cells. PLoS ONE. 2011;6:e26384 pubmed 出版商
Sommer G, Rossa C, Chi A, Neville B, Heise T. Implication of RNA-binding protein La in proliferation, migration and invasion of lymph node-metastasized hypopharyngeal SCC cells. PLoS ONE. 2011;6:e25402 pubmed 出版商
Zammarchi F, de Stanchina E, Bournazou E, Supakorndej T, Martires K, Riedel E, et al. Antitumorigenic potential of STAT3 alternative splicing modulation. Proc Natl Acad Sci U S A. 2011;108:17779-84 pubmed 出版商
Baron Gaillard C, Pallesi Pocachard E, Massey Harroche D, Richard F, Arsanto J, Chauvin J, et al. Hook2 is involved in the morphogenesis of the primary cilium. Mol Biol Cell. 2011;22:4549-62 pubmed 出版商
James R, Walter I, Seebacher F. Variation in expression of calcium-handling proteins is associated with inter-individual differences in mechanical performance of rat (Rattus norvegicus) skeletal muscle. J Exp Biol. 2011;214:3542-8 pubmed 出版商
Chekulaeva M, Mathys H, Zipprich J, Attig J, Colic M, Parker R, et al. miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs. Nat Struct Mol Biol. 2011;18:1218-26 pubmed 出版商
Jing H, Kase J, Dörr J, Milanovic M, Lenze D, Grau M, et al. Opposing roles of NF-?B in anti-cancer treatment outcome unveiled by cross-species investigations. Genes Dev. 2011;25:2137-46 pubmed 出版商
Song B, Liu X, Davis K, Liu X. Plk1 phosphorylation of Orc2 promotes DNA replication under conditions of stress. Mol Cell Biol. 2011;31:4844-56 pubmed 出版商
Du Y, Chou C, Klimstra D, Varmus H. Receptor for hyaluronan-mediated motility isoform B promotes liver metastasis in a mouse model of multistep tumorigenesis and a tail vein assay for metastasis. Proc Natl Acad Sci U S A. 2011;108:16753-8 pubmed 出版商
Wu Y, Wan Y, Jin X, Ouyang B, Bai T, Zhao Y, et al. 25-OCH3-PPD induces the apoptosis of activated t-HSC/Cl-6 cells via c-FLIP-mediated NF-?B activation. Chem Biol Interact. 2011;194:106-12 pubmed 出版商
LeFave C, Squatrito M, Vorlova S, Rocco G, Brennan C, Holland E, et al. Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas. EMBO J. 2011;30:4084-97 pubmed 出版商
Locke J, da Silva Xavier G, Rutter G, Harries L. An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes. Diabetologia. 2011;54:3078-82 pubmed 出版商
Ohno Y, Hattori A, Ueda M, Kageyama S, Yoshiki T, Kakeya H. Multiple NF-Y-binding CCAAT boxes are essential for transcriptional regulation of the human C7orf24 gene, a novel tumor-associated gene. FEBS J. 2011;278:4088-99 pubmed 出版商
Coppe J, Rodier F, Patil C, Freund A, Desprez P, Campisi J. Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype. J Biol Chem. 2011;286:36396-403 pubmed 出版商
Itman C, Wong C, Whiley P, Fernando D, Loveland K. TGFβ superfamily signaling regulators are differentially expressed in the developing and adult mouse testis. Spermatogenesis. 2011;1:63-72 pubmed
Pribat A, Sormani R, Rousseau Gueutin M, Julkowska M, Testerink C, Joubès J, et al. A novel class of PTEN protein in Arabidopsis displays unusual phosphoinositide phosphatase activity and efficiently binds phosphatidic acid. Biochem J. 2012;441:161-71 pubmed 出版商
An H, Shin H, Jo S, Kim Y, Lee J, Paik S, et al. The survival effect of mitochondrial Higd-1a is associated with suppression of cytochrome C release and prevention of caspase activation. Biochim Biophys Acta. 2011;1813:2088-98 pubmed 出版商
Stavik B, Skretting G, Aasheim H, Tinholt M, Zernichow L, Sletten M, et al. Downregulation of TFPI in breast cancer cells induces tyrosine phosphorylation signaling and increases metastatic growth by stimulating cell motility. BMC Cancer. 2011;11:357 pubmed 出版商
Catizone A, Ricci G, Caruso M, Ferranti F, Canipari R, Galdieri M. Hepatocyte growth factor (HGF) regulates blood-testis barrier (BTB) in adult rats. Mol Cell Endocrinol. 2012;348:135-46 pubmed 出版商
Zhou B, Margariti A, Zeng L, Habi O, Xiao Q, Martin D, et al. Splicing of histone deacetylase 7 modulates smooth muscle cell proliferation and neointima formation through nuclear ?-catenin translocation. Arterioscler Thromb Vasc Biol. 2011;31:2676-84 pubmed 出版商
Yim S, Kim Y, Oh S, Fujii J, Zhang Y, Gladyshev V, et al. Identification and characterization of alternatively transcribed form of peroxiredoxin IV gene that is specifically expressed in spermatids of postpubertal mouse testis. J Biol Chem. 2011;286:39002-12 pubmed 出版商
Wei R, Ngo B, Wu G, Lee W. Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint. Mol Biol Cell. 2011;22:3584-94 pubmed 出版商
Evans J, Crown R, Sohn J, Seeger C. West Nile virus infection induces depletion of IFNAR1 protein levels. Viral Immunol. 2011;24:253-63 pubmed 出版商
Feng L, Wang J, Jin H, Qian K, Geng J. SH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complex. Cell Biochem Funct. 2011;29:589-96 pubmed 出版商
Hwang H, Ji J, Jang Y. Phosphorylation of Ran-binding protein-1 by Polo-like kinase-1 is required for interaction with Ran and early mitotic progression. J Biol Chem. 2011;286:33012-20 pubmed 出版商
Ding L, Forsburg S. Schizosaccharomyces pombe minichromosome maintenance-binding protein (MCM-BP) antagonizes MCM helicase. J Biol Chem. 2011;286:32918-30 pubmed 出版商
Tosi G, Forlani G, Andresen V, Turci M, Bertazzoni U, Franchini G, et al. Major histocompatibility complex class II transactivator CIITA is a viral restriction factor that targets human T-cell lymphotropic virus type 1 Tax-1 function and inhibits viral replication. J Virol. 2011;85:10719-29 pubmed 出版商
Ijiri T, Merdiushev T, Cao W, Gerton G. Identification and validation of mouse sperm proteins correlated with epididymal maturation. Proteomics. 2011;11:4047-62 pubmed 出版商
Kwak S, Suk J, Choi J, Yang S, Kim J, Sohn S, et al. Autophagy induction by tetrahydrobiopterin deficiency. Autophagy. 2011;7:1323-34 pubmed 出版商
Kobayashi Y, Shimizu T, Naoe H, Ueki A, Ishizawa J, Chiyoda T, et al. Establishment of a choriocarcinoma model from immortalized normal extravillous trophoblast cells transduced with HRASV12. Am J Pathol. 2011;179:1471-82 pubmed 出版商
Kula A, Guerra J, Knezevich A, Kleva D, Myers M, Marcello A. Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function. Retrovirology. 2011;8:60 pubmed 出版商
Papetti M, Augenlicht L. Mybl2, downregulated during colon epithelial cell maturation, is suppressed by miR-365. Am J Physiol Gastrointest Liver Physiol. 2011;301:G508-18 pubmed 出版商
Drusenheimer N, Nayernia K, Meinhardt A, Jung B, Arnold H, Engel W. Overexpression of Lis1 in different stages of spermatogenesis does not result in an aberrant phenotype. Cytogenet Genome Res. 2011;134:269-82 pubmed 出版商
Grellscheid S, Dalgliesh C, Rozanska A, Grellscheid D, Bourgeois C, Stevenin J, et al. Molecular design of a splicing switch responsive to the RNA binding protein Tra2?. Nucleic Acids Res. 2011;39:8092-104 pubmed 出版商
Seyer P, Grandemange S, Rochard P, Busson M, Pessemesse L, Casas F, et al. P43-dependent mitochondrial activity regulates myoblast differentiation and slow myosin isoform expression by control of Calcineurin expression. Exp Cell Res. 2011;317:2059-71 pubmed 出版商
Baxley R, Soshnev A, Koryakov D, Zhimulev I, Geyer P. The role of the Suppressor of Hairy-wing insulator protein in Drosophila oogenesis. Dev Biol. 2011;356:398-410 pubmed 出版商
Singhmar P, Kumar A. Angelman syndrome protein UBE3A interacts with primary microcephaly protein ASPM, localizes to centrosomes and regulates chromosome segregation. PLoS ONE. 2011;6:e20397 pubmed 出版商
Massone S, Vassallo I, Castelnuovo M, Fiorino G, Gatta E, Robello M, et al. RNA polymerase III drives alternative splicing of the potassium channel-interacting protein contributing to brain complexity and neurodegeneration. J Cell Biol. 2011;193:851-66 pubmed 出版商
Lee K, Kenny A, Rieder C. Caspase activity is not required for the mitotic checkpoint or mitotic slippage in human cells. Mol Biol Cell. 2011;22:2470-9 pubmed 出版商
Lindemann C, Hackmann O, Delic S, Schmidt N, Reifenberger G, Riemenschneider M. SOCS3 promoter methylation is mutually exclusive to EGFR amplification in gliomas and promotes glioma cell invasion through STAT3 and FAK activation. Acta Neuropathol. 2011;122:241-51 pubmed 出版商
Ballmer Hofer K, Andersson A, Ratcliffe L, Berger P. Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output. Blood. 2011;118:816-26 pubmed 出版商
Jin G, Zhang F, Chan K, Xavier Wong H, Liu B, Cheah K, et al. MT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell development. EMBO J. 2011;30:2281-93 pubmed 出版商
Xing Z, Tang X, Gao Y, Da L, Song H, Wang S, et al. The human LIS1 is downregulated in hepatocellular carcinoma and plays a tumor suppressor function. Biochem Biophys Res Commun. 2011;409:193-9 pubmed 出版商
Borysov S, Granic A, Padmanabhan J, Walczak C, Potter H. Alzheimer A? disrupts the mitotic spindle and directly inhibits mitotic microtubule motors. Cell Cycle. 2011;10:1397-410 pubmed
Pefani D, Dimaki M, Spella M, Karantzelis N, Mitsiki E, Kyrousi C, et al. Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression. J Biol Chem. 2011;286:23234-46 pubmed 出版商
Jones C, Ehrlich H. Fibroblast expression of ?-smooth muscle actin, ?2?1 integrin and ?v?3 integrin: influence of surface rigidity. Exp Mol Pathol. 2011;91:394-9 pubmed 出版商
Chen J, Zhang B, Wong N, Lo A, To K, Chan A, et al. Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth. Cancer Res. 2011;71:4138-49 pubmed 出版商
Billig G, Pál B, Fidzinski P, Jentsch T. Ca2+-activated Cl? currents are dispensable for olfaction. Nat Neurosci. 2011;14:763-9 pubmed 出版商
Astiazaran P, Bueno M, Morales E, Kugelman J, Garcia Rivera J, Llano M. HIV-1 integrase modulates the interaction of the HIV-1 cellular cofactor LEDGF/p75 with chromatin. Retrovirology. 2011;8:27 pubmed 出版商
George I, Sabbah H, Xu K, Wang N, Wang J. ?-adrenergic receptor blockade reduces endoplasmic reticulum stress and normalizes calcium handling in a coronary embolization model of heart failure in canines. Cardiovasc Res. 2011;91:447-55 pubmed 出版商
Guarino E, Shepherd M, Salguero I, Hua H, Deegan R, Kearsey S. Cdt1 proteolysis is promoted by dual PIP degrons and is modulated by PCNA ubiquitylation. Nucleic Acids Res. 2011;39:5978-90 pubmed 出版商
Krycer J, Brown A. Cross-talk between the androgen receptor and the liver X receptor: implications for cholesterol homeostasis. J Biol Chem. 2011;286:20637-47 pubmed 出版商
Lanson N, Maltare A, King H, Smith R, Kim J, Taylor J, et al. A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43. Hum Mol Genet. 2011;20:2510-23 pubmed 出版商
Streb J, Long X, Lee T, Sun Q, Kitchen C, Georger M, et al. Retinoid-induced expression and activity of an immediate early tumor suppressor gene in vascular smooth muscle cells. PLoS ONE. 2011;6:e18538 pubmed 出版商
Garcia A, Buisson M, Bertrand P, Rimokh R, Rouleau E, Lopez B, et al. Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers. EMBO Mol Med. 2011;3:279-90 pubmed 出版商
Hegi M, Diserens A, Bady P, Kamoshima Y, Kouwenhoven M, Delorenzi M, et al. Pathway analysis of glioblastoma tissue after preoperative treatment with the EGFR tyrosine kinase inhibitor gefitinib--a phase II trial. Mol Cancer Ther. 2011;10:1102-12 pubmed 出版商
Hamada S, Satoh K, Hirota M, Kanno A, Umino J, Ito H, et al. The homeobox gene MSX2 determines chemosensitivity of pancreatic cancer cells via the regulation of transporter gene ABCG2. J Cell Physiol. 2012;227:729-38 pubmed 出版商
Moshe Y, Bar On O, Ganoth D, Hershko A. Regulation of the action of early mitotic inhibitor 1 on the anaphase-promoting complex/cyclosome by cyclin-dependent kinases. J Biol Chem. 2011;286:16647-57 pubmed 出版商
Alakhras R, Stephanou G, Demopoulos N, Nikolaropoulos S. Genotoxicity of all-trans retinoic acid (ATRA) and its steroidal analogue EA-4 in human lymphocytes and mouse cells in vitro. Cancer Lett. 2011;306:15-26 pubmed 出版商
Bernabo N, Berardinelli P, Mauro A, Russo V, Lucidi P, Mattioli M, et al. The role of actin in capacitation-related signaling: an in silico and in vitro study. BMC Syst Biol. 2011;5:47 pubmed 出版商
Bier C, Knauer S, Docter D, Schneider G, Kramer O, Stauber R. The importin-alpha/nucleophosmin switch controls taspase1 protease function. Traffic. 2011;12:703-14 pubmed 出版商
Das M, Garlick D, Greiner D, Davis R. The role of JNK in the development of hepatocellular carcinoma. Genes Dev. 2011;25:634-45 pubmed 出版商
Zhang R, Wang J, Ma S, Huang Z, Zhang G. Requirement of Osteopontin in the migration and protection against Taxol-induced apoptosis via the ATX-LPA axis in SGC7901 cells. BMC Cell Biol. 2011;12:11 pubmed 出版商
Kveiborg M, Instrell R, Rowlands C, Howell M, Parker P. PKC? and PKC? regulate ADAM17-mediated ectodomain shedding of heparin binding-EGF through separate pathways. PLoS ONE. 2011;6:e17168 pubmed 出版商
Gore A, Li Z, Fung H, Young J, Agarwal S, Antosiewicz Bourget J, et al. Somatic coding mutations in human induced pluripotent stem cells. Nature. 2011;471:63-7 pubmed 出版商
Brumby A, Goulding K, Schlosser T, Loi S, Galea R, Khoo P, et al. Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis. Genetics. 2011;188:105-25 pubmed 出版商
Morency E, Anguish L, Coonrod S. Subcellular localization of cytoplasmic lattice-associated proteins is dependent upon fixation and processing procedures. PLoS ONE. 2011;6:e17226 pubmed 出版商
Thorslund S, Edgren T, Pettersson J, Nordfelth R, Sellin M, Ivanova E, et al. The RACK1 signaling scaffold protein selectively interacts with Yersinia pseudotuberculosis virulence function. PLoS ONE. 2011;6:e16784 pubmed 出版商
Vande Velde G, Rangarajan J, Toelen J, Dresselaers T, Ibrahimi A, Krylychkina O, et al. Evaluation of the specificity and sensitivity of ferritin as an MRI reporter gene in the mouse brain using lentiviral and adeno-associated viral vectors. Gene Ther. 2011;18:594-605 pubmed 出版商
Liu G, Barkho B, Ruiz S, Diep D, Qu J, Yang S, et al. Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome. Nature. 2011;472:221-5 pubmed 出版商
Chen R, Dioum E, Hogg R, Gerard R, Garcia J. Hypoxia increases sirtuin 1 expression in a hypoxia-inducible factor-dependent manner. J Biol Chem. 2011;286:13869-78 pubmed 出版商
Hein N, Jiang K, Cornelissen C, Luscher B. TGF?1 enhances MAD1 expression and stimulates promoter-bound Pol II phosphorylation: basic functions of C/EBP, SP and SMAD3 transcription factors. BMC Mol Biol. 2011;12:9 pubmed 出版商
Mouguelar V, Cabada M, Coux G. The integrin-binding motif RGDS induces protein tyrosine phosphorylation without activation in Bufo arenarum (Amphibia) oocytes. Reproduction. 2011;141:581-93 pubmed 出版商
Gannon H, Donehower L, Lyle S, Jones S. Mdm2-p53 signaling regulates epidermal stem cell senescence and premature aging phenotypes in mouse skin. Dev Biol. 2011;353:1-9 pubmed 出版商
Münch C, O BRIEN J, Bertolotti A. Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells. Proc Natl Acad Sci U S A. 2011;108:3548-53 pubmed 出版商
Liang X, Crooke S. Depletion of key protein components of the RISC pathway impairs pre-ribosomal RNA processing. Nucleic Acids Res. 2011;39:4875-89 pubmed 出版商
Li H, Daculsi R, Grellier M, Bareille R, Bourget C, Remy M, et al. The role of vascular actors in two dimensional dialogue of human bone marrow stromal cell and endothelial cell for inducing self-assembled network. PLoS ONE. 2011;6:e16767 pubmed 出版商
Kim J, Burghardt R, Wu G, Johnson G, Spencer T, Bazer F. Select nutrients in the ovine uterine lumen. IX. Differential effects of arginine, leucine, glutamine, and glucose on interferon tau, ornithine decarboxylase, and nitric oxide synthase in the ovine conceptus. Biol Reprod. 2011;84:1139-47 pubmed 出版商
Cheong J, Nguyen T, Wang H, Tan P, Voorhoeve P, Lee S, et al. IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1?/? and Wnt/?-catenin independent inhibition of mitotic spindle formation. Oncogene. 2011;30:2558-69 pubmed 出版商
Barrett R, Colnaghi R, Wheatley S. Threonine 48 in the BIR domain of survivin is critical to its mitotic and anti-apoptotic activities and can be phosphorylated by CK2 in vitro. Cell Cycle. 2011;10:538-48 pubmed
Hiragami Hamada K, Shinmyozu K, Hamada D, Tatsu Y, Uegaki K, Fujiwara S, et al. N-terminal phosphorylation of HP1{alpha} promotes its chromatin binding. Mol Cell Biol. 2011;31:1186-200 pubmed 出版商
Vaishnav M, MacFarlane M, Dickens M. Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis. Exp Cell Res. 2011;317:1028-39 pubmed 出版商
Masuda H, Fong C, Ohtsuki C, Haraguchi T, Hiraoka Y. Spatiotemporal regulations of Wee1 at the G2/M transition. Mol Biol Cell. 2011;22:555-69 pubmed 出版商
Perez V, Ali Z, Alastalo T, Ikeno F, Sawada H, Lai Y, et al. BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways. J Cell Biol. 2011;192:171-88 pubmed 出版商
Lazzari C, Peggion C, Stella R, Massimino M, Lim D, Bertoli A, et al. Cellular prion protein is implicated in the regulation of local Ca2+ movements in cerebellar granule neurons. J Neurochem. 2011;116:881-90 pubmed 出版商
de Oliveira V, Almeida S, Soares H, Crespo A, Marshall Clarke S, Parkhouse R. A novel TLR3 inhibitor encoded by African swine fever virus (ASFV). Arch Virol. 2011;156:597-609 pubmed 出版商
Rico Bautista E, Yang C, Lu L, Roth G, Wolf D. Chemical genetics approach to restoring p27Kip1 reveals novel compounds with antiproliferative activity in prostate cancer cells. BMC Biol. 2010;8:153 pubmed 出版商
Zhang Y, Qu Z, Kim S, Shi V, Liao B, Kraft P, et al. Down-modulation of cancer targets using locked nucleic acid (LNA)-based antisense oligonucleotides without transfection. Gene Ther. 2011;18:326-33 pubmed 出版商
Takezawa J, Ishimi Y, Aiba N, Yamada K. Rev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation. J Nucleic Acids. 2010;2010:750296 pubmed 出版商
Wang S, Durrant W, Song J, Spivey N, Dong X. Arabidopsis BRCA2 and RAD51 proteins are specifically involved in defense gene transcription during plant immune responses. Proc Natl Acad Sci U S A. 2010;107:22716-21 pubmed 出版商
Kan R, Yurttas P, Kim B, Jin M, Wo L, Lee B, et al. Regulation of mouse oocyte microtubule and organelle dynamics by PADI6 and the cytoplasmic lattices. Dev Biol. 2011;350:311-22 pubmed 出版商
Soshnikova N, Montavon T, Leleu M, Galjart N, Duboule D. Functional analysis of CTCF during mammalian limb development. Dev Cell. 2010;19:819-30 pubmed 出版商
Takiguchi M, James C, Josefsson E, Carmichael C, Premsrirut P, Lowe S, et al. Transgenic, inducible RNAi in megakaryocytes and platelets in mice. J Thromb Haemost. 2010;8:2751-6 pubmed 出版商
Ayala Y, De Conti L, Avendaño Vázquez S, Dhir A, Romano M, D Ambrogio A, et al. TDP-43 regulates its mRNA levels through a negative feedback loop. EMBO J. 2011;30:277-88 pubmed 出版商
Rodier F, Muñoz D, Teachenor R, Chu V, Le O, Bhaumik D, et al. DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion. J Cell Sci. 2011;124:68-81 pubmed 出版商
Allen E, Carlson K, Zigmond M, Cavanaugh J. L-DOPA reverses motor deficits associated with normal aging in mice. Neurosci Lett. 2011;489:1-4 pubmed 出版商
Gao X, Shin Y, Li M, Wang F, Tong Q, Zhang P. The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice. PLoS ONE. 2010;5:e14005 pubmed 出版商
Furuya K, Miyabe I, Tsutsui Y, Paderi F, Kakusho N, Masai H, et al. DDK phosphorylates checkpoint clamp component Rad9 and promotes its release from damaged chromatin. Mol Cell. 2010;40:606-18 pubmed 出版商
Mendoza Maldonado R, Paolinelli R, Galbiati L, Giadrossi S, Giacca M. Interaction of the retinoblastoma protein with Orc1 and its recruitment to human origins of DNA replication. PLoS ONE. 2010;5:e13720 pubmed 出版商
Tougan T, Kasama T, Ohtaka A, Okuzaki D, Saito T, Russell P, et al. The Mek1 phosphorylation cascade plays a role in meiotic recombination of Schizosaccharomyces pombe. Cell Cycle. 2010;9:4688-702 pubmed
Takahashi Y, Meyerkord C, Hori T, Runkle K, Fox T, Kester M, et al. Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy. Autophagy. 2011;7:61-73 pubmed
Liang X, Vickers T, Guo S, Crooke S. Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice. Nucleic Acids Res. 2011;39:e13 pubmed 出版商
Lewis Tuffin L, Rodriguez F, Giannini C, Scheithauer B, Necela B, Sarkaria J, et al. Misregulated E-cadherin expression associated with an aggressive brain tumor phenotype. PLoS ONE. 2010;5:e13665 pubmed 出版商
Llewellyn G, Hogue I, Grover J, Ono A. Nucleocapsid promotes localization of HIV-1 gag to uropods that participate in virological synapses between T cells. PLoS Pathog. 2010;6:e1001167 pubmed 出版商
Delekta P, Apel I, Gu S, Siu K, Hattori Y, McAllister Lucas L, et al. Thrombin-dependent NF-{kappa}B activation and monocyte/endothelial adhesion are mediated by the CARMA3·Bcl10·MALT1 signalosome. J Biol Chem. 2010;285:41432-42 pubmed 出版商
Hendrix J, Gijsbers R, De Rijck J, Voet A, Hotta J, McNeely M, et al. The transcriptional co-activator LEDGF/p75 displays a dynamic scan-and-lock mechanism for chromatin tethering. Nucleic Acids Res. 2011;39:1310-25 pubmed 出版商
Malekkou A, Lederer C, Lamond A, Santama N. The nuclear ATPase/adenylate kinase hCINAP is recruited to perinucleolar caps generated upon RNA pol.II inhibition. FEBS Lett. 2010;584:4559-64 pubmed 出版商
Keech O, Pesquet E, Gutierrez L, Ahad A, Bellini C, Smith S, et al. Leaf senescence is accompanied by an early disruption of the microtubule network in Arabidopsis. Plant Physiol. 2010;154:1710-20 pubmed 出版商
Riley M, McBride K, Cole S. NOTCH1 missense alleles associated with left ventricular outflow tract defects exhibit impaired receptor processing and defective EMT. Biochim Biophys Acta. 2011;1812:121-9 pubmed 出版商
Laloux G, Deghelt M, de Barsy M, Letesson J, De Bolle X. Identification of the essential Brucella melitensis porin Omp2b as a suppressor of Bax-induced cell death in yeast in a genome-wide screening. PLoS ONE. 2010;5:e13274 pubmed 出版商
Klein A, Maldonado C, Vargas L, Gonzalez M, Robledo F, Perez de Arce K, et al. Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons. Neurobiol Dis. 2011;41:209-18 pubmed 出版商
Nedelsky N, Pennuto M, Smith R, Palazzolo I, Moore J, Nie Z, et al. Native functions of the androgen receptor are essential to pathogenesis in a Drosophila model of spinobulbar muscular atrophy. Neuron. 2010;67:936-52 pubmed 出版商
Durieux A, Vignaud A, Prudhon B, Viou M, Beuvin M, Vassilopoulos S, et al. A centronuclear myopathy-dynamin 2 mutation impairs skeletal muscle structure and function in mice. Hum Mol Genet. 2010;19:4820-36 pubmed 出版商
Kim J, Burghardt R, Wu G, Johnson G, Spencer T, Bazer F. Select nutrients in the ovine uterine lumen. VII. Effects of arginine, leucine, glutamine, and glucose on trophectoderm cell signaling, proliferation, and migration. Biol Reprod. 2011;84:62-9 pubmed 出版商
Kim J, Burghardt R, Wu G, Johnson G, Spencer T, Bazer F. Select nutrients in the ovine uterine lumen. VIII. Arginine stimulates proliferation of ovine trophectoderm cells through MTOR-RPS6K-RPS6 signaling cascade and synthesis of nitric oxide and polyamines. Biol Reprod. 2011;84:70-8 pubmed 出版商
Uetake Y, Sluder G. Prolonged prometaphase blocks daughter cell proliferation despite normal completion of mitosis. Curr Biol. 2010;20:1666-71 pubmed 出版商
Choi H, Chang J, Jung Y. Peroxiredoxin 6 interferes with TRAIL-induced death-inducing signaling complex formation by binding to death effector domain caspase. Cell Death Differ. 2011;18:405-14 pubmed 出版商
Sobinoff A, Pye V, Nixon B, Roman S, McLaughlin E. Adding insult to injury: effects of xenobiotic-induced preantral ovotoxicity on ovarian development and oocyte fusibility. Toxicol Sci. 2010;118:653-66 pubmed 出版商
Gavicherla B, Ritchey L, Gianfelice A, Kolokoltsov A, Davey R, Ireton K. Critical role for the host GTPase-activating protein ARAP2 in InlB-mediated entry of Listeria monocytogenes. Infect Immun. 2010;78:4532-41 pubmed 出版商
Zhao R, Hou Y, Xue P, Woods C, Fu J, Feng B, et al. Long isoforms of NRF1 contribute to arsenic-induced antioxidant response in human keratinocytes. Environ Health Perspect. 2011;119:56-62 pubmed 出版商
Jin H, Jin X, Lee J. Zinc-finger protein 91 plays a key role in LIGHT-induced activation of non-canonical NF-?B pathway. Biochem Biophys Res Commun. 2010;400:581-6 pubmed 出版商
Alonso F, Boittin F, Beny J, Haefliger J. Loss of connexin40 is associated with decreased endothelium-dependent relaxations and eNOS levels in the mouse aorta. Am J Physiol Heart Circ Physiol. 2010;299:H1365-73 pubmed 出版商
Göb E, Schmitt J, Benavente R, Alsheimer M. Mammalian sperm head formation involves different polarization of two novel LINC complexes. PLoS ONE. 2010;5:e12072 pubmed 出版商
Madison D, Lundblad J. C-terminal binding protein and poly(ADP)ribose polymerase 1 contribute to repression of the p21(waf1/cip1) promoter. Oncogene. 2010;29:6027-39 pubmed 出版商
Altamura S, D Alessio F, Selle B, Muckenthaler M. A novel TMPRSS6 mutation that prevents protease auto-activation causes IRIDA. Biochem J. 2010;431:363-71 pubmed 出版商
Aubele M, Spears M, Ludyga N, Braselmann H, Feuchtinger A, Taylor K, et al. In situ quantification of HER2-protein tyrosine kinase 6 (PTK6) protein-protein complexes in paraffin sections from breast cancer tissues. Br J Cancer. 2010;103:663-7 pubmed 出版商
Jin X, Jin H, Jung H, Lee S, Lee J, Lee J. An atypical E3 ligase zinc finger protein 91 stabilizes and activates NF-kappaB-inducing kinase via Lys63-linked ubiquitination. J Biol Chem. 2010;285:30539-47 pubmed 出版商
Kraniak J, Sun D, Mattingly R, Reiners J, Tainsky M. The role of neurofibromin in N-Ras mediated AP-1 regulation in malignant peripheral nerve sheath tumors. Mol Cell Biochem. 2010;344:267-76 pubmed 出版商
Cho R, Song Y, Littleton J. Comparative analysis of Drosophila and mammalian complexins as fusion clamps and facilitators of neurotransmitter release. Mol Cell Neurosci. 2010;45:389-97 pubmed 出版商
Goitre L, Balzac F, Degani S, Degan P, Marchi S, Pinton P, et al. KRIT1 regulates the homeostasis of intracellular reactive oxygen species. PLoS ONE. 2010;5:e11786 pubmed 出版商
Divecha N. Methods to assess changes in the pattern of nuclear phosphoinositides. Methods Mol Biol. 2010;645:165-77 pubmed 出版商
Heilmann A, Calderwood M, Johannsen E. Epstein-Barr virus LF2 protein regulates viral replication by altering Rta subcellular localization. J Virol. 2010;84:9920-31 pubmed 出版商
Leak R, Castro S, Jaumotte J, Smith A, Zigmond M. Assaying multiple biochemical variables from the same tissue sample. J Neurosci Methods. 2010;191:234-8 pubmed 出版商
D Angiolella V, Donato V, Vijayakumar S, Saraf A, Florens L, Washburn M, et al. SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation. Nature. 2010;466:138-42 pubmed 出版商
Wang X, Zhang L, Zhong X, Xing X, Liu Y, Niu Z, et al. S100A6 overexpression is associated with poor prognosis and is epigenetically up-regulated in gastric cancer. Am J Pathol. 2010;177:586-97 pubmed 出版商
Friboulet L, Gourzones C, Tsao S, Morel Y, Paturel C, Temam S, et al. Poly(I:C) induces intense expression of c-IAP2 and cooperates with an IAP inhibitor in induction of apoptosis in cancer cells. BMC Cancer. 2010;10:327 pubmed 出版商
del Rey J, Prat E, Ponsa I, Lloreta J, Gelabert A, Algaba F, et al. Centrosome clustering and cyclin D1 gene amplification in double minutes are common events in chromosomal unstable bladder tumors. BMC Cancer. 2010;10:280 pubmed 出版商
Chekulaeva M, Parker R, Filipowicz W. The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression. Nucleic Acids Res. 2010;38:6673-83 pubmed 出版商
Chapman S, Liu X, Meyers C, Schlegel R, McBride A. Human keratinocytes are efficiently immortalized by a Rho kinase inhibitor. J Clin Invest. 2010;120:2619-26 pubmed 出版商
Buchwald M, Pietschmann K, Muller J, Bohmer F, Heinzel T, Krämer O. Ubiquitin conjugase UBCH8 targets active FMS-like tyrosine kinase 3 for proteasomal degradation. Leukemia. 2010;24:1412-21 pubmed 出版商
Temme C, Zhang L, Kremmer E, Ihling C, Chartier A, Sinz A, et al. Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation. RNA. 2010;16:1356-70 pubmed 出版商
Hendrix A, Maynard D, Pauwels P, Braems G, Denys H, Van Den Broecke R, et al. Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis. J Natl Cancer Inst. 2010;102:866-80 pubmed 出版商
Van Marck V, Stove C, Jacobs K, Van den Eynden G, Bracke M. P-cadherin in adhesion and invasion: opposite roles in colon and bladder carcinoma. Int J Cancer. 2011;128:1031-44 pubmed 出版商
Arora S, Kothandapani A, Tillison K, Kalman Maltese V, Patrick S. Downregulation of XPF-ERCC1 enhances cisplatin efficacy in cancer cells. DNA Repair (Amst). 2010;9:745-53 pubmed 出版商
Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, et al. Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy. J Neurosci. 2010;30:5702-12 pubmed 出版商
Woodward E, Prele C, Nicholson S, Kolesnik T, Hart P. The anti-inflammatory effects of interleukin-4 are not mediated by suppressor of cytokine signalling-1 (SOCS1). Immunology. 2010;131:118-27 pubmed 出版商
Dovey O, Foster C, Cowley S. Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation. Proc Natl Acad Sci U S A. 2010;107:8242-7 pubmed 出版商
Claeys K, Sozanska M, Martin J, Lacene E, Vignaud L, Stockholm D, et al. DNAJB2 expression in normal and diseased human and mouse skeletal muscle. Am J Pathol. 2010;176:2901-10 pubmed 出版商
Tall E, Bernstein A, Oliver N, Gray J, Masur S. TGF-?-stimulated CTGF production enhanced by collagen and associated with biogenesis of a novel 31-kDa CTGF form in human corneal fibroblasts. Invest Ophthalmol Vis Sci. 2010;51:5002-11 pubmed 出版商
Schulte J, Sepp K, Jorquera R, Wu C, Song Y, Hong P, et al. DMob4/Phocein regulates synapse formation, axonal transport, and microtubule organization. J Neurosci. 2010;30:5189-203 pubmed 出版商
Imamura M, Long X, Nanda V, Miano J. Expression and functional activity of four myocardin isoforms. Gene. 2010;464:1-10 pubmed 出版商
Geoui T, Urlaub H, Plessmann U, Porschewski P. Extraction of proteins from formalin-fixed, paraffin-embedded tissue using the Qproteome extraction technique and preparation of tryptic peptides for liquid chromatography/mass spectrometry analysis. Curr Protoc Mol Biol. 2010;Chapter 10:Unit 10.27.1-12 pubmed 出版商
Nuutinen T, Suuronen T, Kauppinen A, Salminen A. Valproic acid stimulates clusterin expression in human astrocytes: Implications for Alzheimer's disease. Neurosci Lett. 2010;475:64-8 pubmed 出版商
Terreni M, Valentini P, Liverani V, Gutierrez M, Di Primio C, Di Fenza A, et al. GCN5-dependent acetylation of HIV-1 integrase enhances viral integration. Retrovirology. 2010;7:18 pubmed 出版商
Elloul S, Vaksman O, Stavnes H, Trope C, Davidson B, Reich R. Mesenchymal-to-epithelial transition determinants as characteristics of ovarian carcinoma effusions. Clin Exp Metastasis. 2010;27:161-72 pubmed 出版商
Ge X, Frank C, Calderon de Anda F, Tsai L. Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesis. Neuron. 2010;65:191-203 pubmed 出版商
Kuo H, Lee D, Chen C, Liu M, Chou C, Lee H, et al. ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Sci Signal. 2010;3:ra9 pubmed 出版商
Sluss H, Gannon H, Coles A, Shen Q, Eischen C, Jones S. Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis. Mol Cancer Res. 2010;8:216-22 pubmed 出版商
Cronin T, Raffelsberger W, Lee Rivera I, Jaillard C, Niepon M, Kinzel B, et al. The disruption of the rod-derived cone viability gene leads to photoreceptor dysfunction and susceptibility to oxidative stress. Cell Death Differ. 2010;17:1199-210 pubmed 出版商
Barton E, DeMeo J, Lei H. The insulin-like growth factor (IGF)-I E-peptides are required for isoform-specific gene expression and muscle hypertrophy after local IGF-I production. J Appl Physiol (1985). 2010;108:1069-76 pubmed 出版商
Beauclair L, Yu A, Bouche N. microRNA-directed cleavage and translational repression of the copper chaperone for superoxide dismutase mRNA in Arabidopsis. Plant J. 2010;62:454-62 pubmed 出版商
Czymai T, Viemann D, Sticht C, Molema G, Goebeler M, Schmidt M. FOXO3 modulates endothelial gene expression and function by classical and alternative mechanisms. J Biol Chem. 2010;285:10163-78 pubmed 出版商
Alonso F, Krattinger N, Mazzolai L, Simon A, Waeber G, Meda P, et al. An angiotensin II- and NF-kappaB-dependent mechanism increases connexin 43 in murine arteries targeted by renin-dependent hypertension. Cardiovasc Res. 2010;87:166-76 pubmed 出版商
Solinger J, Paolinelli R, Klöss H, Scorza F, Marchesi S, Sauder U, et al. The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation. PLoS Genet. 2010;6:e1000820 pubmed 出版商
Sepulveda F, Bustos F, Inostroza E, Zuniga F, Neve R, Montecino M, et al. Differential roles of NMDA Receptor Subtypes NR2A and NR2B in dendritic branch development and requirement of RasGRF1. J Neurophysiol. 2010;103:1758-70 pubmed 出版商
Macurek L, Lindqvist A, Voets O, Kool J, Vos H, Medema R. Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition. Oncogene. 2010;29:2281-91 pubmed 出版商
Jinwal U, Koren J, Borysov S, Schmid A, Abisambra J, Blair L, et al. The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules. J Neurosci. 2010;30:591-9 pubmed 出版商
Wang Z, Udeshi N, Slawson C, Compton P, Sakabe K, Cheung W, et al. Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis. Sci Signal. 2010;3:ra2 pubmed 出版商
Zimmermann T, Moehler M, Gockel I, Sgourakis G, Biesterfeld S, Muller M, et al. Low expression of chemokine receptor CCR5 in human colorectal cancer correlates with lymphatic dissemination and reduced CD8+ T-cell infiltration. Int J Colorectal Dis. 2010;25:417-24 pubmed 出版商
Almeida A, Wise H, Hindley C, Slevin M, Hartley R, Philpott A. The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevis. Neural Dev. 2010;5:1 pubmed 出版商
Penna F, Bonetto A, Muscaritoli M, Costamagna D, Minero V, Bonelli G, et al. Muscle atrophy in experimental cancer cachexia: is the IGF-1 signaling pathway involved?. Int J Cancer. 2010;127:1706-17 pubmed 出版商
Granic A, Padmanabhan J, Norden M, Potter H. Alzheimer Abeta peptide induces chromosome mis-segregation and aneuploidy, including trisomy 21: requirement for tau and APP. Mol Biol Cell. 2010;21:511-20 pubmed 出版商
Parada Bustamante A, Orihuela P, Rios M, Cuevas C, Oróstica M, Velasquez L, et al. A non-genomic signaling pathway shut down by mating changes the estradiol-induced gene expression profile in the rat oviduct. Reproduction. 2010;139:631-44 pubmed 出版商
Whelan S, Dias W, Thiruneelakantapillai L, Lane M, Hart G. Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytes. J Biol Chem. 2010;285:5204-11 pubmed 出版商
Cleveland B, Weber G. Effects of insulin-like growth factor-I, insulin, and leucine on protein turnover and ubiquitin ligase expression in rainbow trout primary myocytes. Am J Physiol Regul Integr Comp Physiol. 2010;298:R341-50 pubmed 出版商
Cohen E, Du D, Joyce D, Kapernick E, Volovik Y, Kelly J, et al. Temporal requirements of insulin/IGF-1 signaling for proteotoxicity protection. Aging Cell. 2010;9:126-34 pubmed 出版商
Jablonski J, Amelio A, Giacca M, Caputi M. The transcriptional transactivator Tat selectively regulates viral splicing. Nucleic Acids Res. 2010;38:1249-60 pubmed 出版商
Hsu S, Miller S, Wang Y, Hung M. Nuclear EGFR is required for cisplatin resistance and DNA repair. Am J Transl Res. 2009;1:249-58 pubmed
Castanotto D, Lingeman R, Riggs A, Rossi J. CRM1 mediates nuclear-cytoplasmic shuttling of mature microRNAs. Proc Natl Acad Sci U S A. 2009;106:21655-9 pubmed 出版商
Bouissou A, Verollet C, Sousa A, Sampaio P, Wright M, Sunkel C, et al. {gamma}-Tubulin ring complexes regulate microtubule plus end dynamics. J Cell Biol. 2009;187:327-34 pubmed 出版商
Xiong S, Salazar G, San Martin A, Ahmad M, Patrushev N, Hilenski L, et al. PGC-1 alpha serine 570 phosphorylation and GCN5-mediated acetylation by angiotensin II drive catalase down-regulation and vascular hypertrophy. J Biol Chem. 2010;285:2474-87 pubmed 出版商
Zwerger M, Kolb T, Richter K, Karakesisoglou I, Herrmann H. Induction of a massive endoplasmic reticulum and perinuclear space expansion by expression of lamin B receptor mutants and the related sterol reductases TM7SF2 and DHCR7. Mol Biol Cell. 2010;21:354-68 pubmed 出版商
Averette K, Pratt M, Yang Y, Bassilian S, Whitelegge J, Loo J, et al. Anthrax lethal toxin induced lysosomal membrane permeabilization and cytosolic cathepsin release is Nlrp1b/Nalp1b-dependent. PLoS ONE. 2009;4:e7913 pubmed 出版商
Leivar P, Tepperman J, Monte E, Calderon R, Liu T, Quail P. Definition of early transcriptional circuitry involved in light-induced reversal of PIF-imposed repression of photomorphogenesis in young Arabidopsis seedlings. Plant Cell. 2009;21:3535-53 pubmed 出版商
DUPART J, Trent J, Lee H, Hess K, Godwin A, Taguchi T, et al. Insulin-like growth factor binding protein-3 has dual effects on gastrointestinal stromal tumor cell viability and sensitivity to the anti-tumor effects of imatinib mesylate in vitro. Mol Cancer. 2009;8:99 pubmed 出版商
Li H, Lu Y. Phenotypic inheritance induced by hairpin RNA in Drosophila. Acta Biochim Biophys Sin (Shanghai). 2009;41:922-8 pubmed
Nakamura N, Mori C, Eddy E. Molecular complex of three testis-specific isozymes associated with the mouse sperm fibrous sheath: hexokinase 1, phosphofructokinase M, and glutathione S-transferase mu class 5. Biol Reprod. 2010;82:504-15 pubmed 出版商
Garcia Rivera J, Bueno M, Morales E, Kugelman J, Rodriguez D, Llano M. Implication of serine residues 271, 273, and 275 in the human immunodeficiency virus type 1 cofactor activity of lens epithelium-derived growth factor/p75. J Virol. 2010;84:740-52 pubmed 出版商
Zhu D, Fang J, Li Y, Zhang J. Mbd3, a component of NuRD/Mi-2 complex, helps maintain pluripotency of mouse embryonic stem cells by repressing trophectoderm differentiation. PLoS ONE. 2009;4:e7684 pubmed 出版商
Schulze S, Curio Penny B, Speese S, Dialynas G, Cryderman D, McDonough C, et al. A comparative study of Drosophila and human A-type lamins. PLoS ONE. 2009;4:e7564 pubmed 出版商
Heliövaara E, Raitila A, Launonen V, Paetau A, Arola J, Lehtonen H, et al. The expression of AIP-related molecules in elucidation of cellular pathways in pituitary adenomas. Am J Pathol. 2009;175:2501-7 pubmed 出版商
Pham Y, Tu Y, Wu T, Allen T, Calkin A, Watson A, et al. Cell division autoantigen 1 plays a profibrotic role by modulating downstream signalling of TGF-beta in a murine diabetic model of atherosclerosis. Diabetologia. 2010;53:170-9 pubmed 出版商
Williams T, Forsberg L, Viollet B, Brenman J. Basal autophagy induction without AMP-activated protein kinase under low glucose conditions. Autophagy. 2009;5:1155-65 pubmed
Alexandrova E, Sokol S. Xenopus axin-related protein: a link between its centrosomal localization and function in the Wnt/beta-catenin pathway. Dev Dyn. 2010;239:261-70 pubmed 出版商
Iliopoulos D, Polytarchou C, Hatziapostolou M, Kottakis F, Maroulakou I, Struhl K, et al. MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells. Sci Signal. 2009;2:ra62 pubmed 出版商
Stratman A, Malotte K, Mahan R, Davis M, Davis G. Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood. 2009;114:5091-101 pubmed 出版商
Zong F, Fthenou E, Wolmer N, Hollosi P, Kovalszky I, Szilak L, et al. Syndecan-1 and FGF-2, but not FGF receptor-1, share a common transport route and co-localize with heparanase in the nuclei of mesenchymal tumor cells. PLoS ONE. 2009;4:e7346 pubmed 出版商
Wang Y, Cheong C, Hall T, Wang Z. Engineering splicing factors with designed specificities. Nat Methods. 2009;6:825-30 pubmed 出版商
Long X, Tharp D, Georger M, Slivano O, Lee M, Wamhoff B, et al. The smooth muscle cell-restricted KCNMB1 ion channel subunit is a direct transcriptional target of serum response factor and myocardin. J Biol Chem. 2009;284:33671-82 pubmed 出版商
Rajabian T, Gavicherla B, Heisig M, Müller Altrock S, Goebel W, Gray Owen S, et al. The bacterial virulence factor InlC perturbs apical cell junctions and promotes cell-to-cell spread of Listeria. Nat Cell Biol. 2009;11:1212-8 pubmed 出版商
Miyamoto M, Aoki M, Hirai K, Sugimoto S, Kawasaki K, Imai R. A nonsense mutation in Gnat1, encoding the alpha subunit of rod transducin, in spontaneous mouse models of retinal dysfunction. Exp Eye Res. 2010;90:63-9 pubmed 出版商
Ohayon D, Pattyn A, Venteo S, Valmier J, Carroll P, Garces A. Zfh1 promotes survival of a peripheral glia subtype by antagonizing a Jun N-terminal kinase-dependent apoptotic pathway. EMBO J. 2009;28:3228-43 pubmed 出版商
Fontanes V, Raychaudhuri S, Dasgupta A. A cell-permeable peptide inhibits hepatitis C virus replication by sequestering IRES transacting factors. Virology. 2009;394:82-90 pubmed 出版商
Dodson H, Morrison C. Increased sister chromatid cohesion and DNA damage response factor localization at an enzyme-induced DNA double-strand break in vertebrate cells. Nucleic Acids Res. 2009;37:6054-63 pubmed 出版商
Castets P, Maugenre S, Gartioux C, Rederstorff M, Krol A, Lescure A, et al. Selenoprotein N is dynamically expressed during mouse development and detected early in muscle precursors. BMC Dev Biol. 2009;9:46 pubmed 出版商
Vogt A, McPherson P, Shen X, Balachandran R, Zhu G, Raccor B, et al. High-content analysis of cancer-cell-specific apoptosis and inhibition of in vivo angiogenesis by synthetic (-)-pironetin and analogs. Chem Biol Drug Des. 2009;74:358-68 pubmed 出版商
Chera S, Ghila L, Dobretz K, Wenger Y, Bauer C, Buzgariu W, et al. Apoptotic cells provide an unexpected source of Wnt3 signaling to drive hydra head regeneration. Dev Cell. 2009;17:279-89 pubmed 出版商
Rudinskiy N, Kaneko Y, Beesen A, Gokce O, Regulier E, Déglon N, et al. Diminished hippocalcin expression in Huntington's disease brain does not account for increased striatal neuron vulnerability as assessed in primary neurons. J Neurochem. 2009;111:460-72 pubmed 出版商
Kawamura T, Suzuki J, Wang Y, Menendez S, Morera L, Raya A, et al. Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature. 2009;460:1140-4 pubmed 出版商
Solt L, Madge L, May M. NEMO-binding domains of both IKKalpha and IKKbeta regulate IkappaB kinase complex assembly and classical NF-kappaB activation. J Biol Chem. 2009;284:27596-608 pubmed 出版商
Shah A, Friedman M, Huang S, Roberts M, Li X, Li S. Transcriptional dysregulation of TrkA associates with neurodegeneration in spinocerebellar ataxia type 17. Hum Mol Genet. 2009;18:4141-52 pubmed 出版商
Jeninga E, Bugge A, Nielsen R, Kersten S, Hamers N, Dani C, et al. Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81). J Biol Chem. 2009;284:26385-93 pubmed 出版商
Hsiao Y, Tong Z, Westfall J, Ault J, Page McCaw P, Ferland R. Ahi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle trafficking. Hum Mol Genet. 2009;18:3926-41 pubmed 出版商
Rodier F, Coppe J, Patil C, Hoeijmakers W, Muñoz D, Raza S, et al. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat Cell Biol. 2009;11:973-9 pubmed 出版商
Minichsdorfer C, Hohenegger M. Autocrine amplification loop in statin-induced apoptosis of human melanoma cells. Br J Pharmacol. 2009;157:1278-90 pubmed 出版商
Freedman J, Chang J, Jakoi L, Nevins J. A combinatorial mechanism for determining the specificity of E2F activation and repression. Oncogene. 2009;28:2873-81 pubmed 出版商
Moiseeva O, Bourdeau V, Roux A, Deschênes Simard X, Ferbeyre G. Mitochondrial dysfunction contributes to oncogene-induced senescence. Mol Cell Biol. 2009;29:4495-507 pubmed 出版商
Ricci E, Mure F, Gruffat H, Decimo D, Medina Palazon C, Ohlmann T, et al. Translation of intronless RNAs is strongly stimulated by the Epstein-Barr virus mRNA export factor EB2. Nucleic Acids Res. 2009;37:4932-43 pubmed 出版商
Dormann D, Capell A, Carlson A, Shankaran S, Rodde R, Neumann M, et al. Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin. J Neurochem. 2009;110:1082-94 pubmed 出版商
Morin P, Flors C, Olson M. Constitutively active RhoA inhibits proliferation by retarding G(1) to S phase cell cycle progression and impairing cytokinesis. Eur J Cell Biol. 2009;88:495-507 pubmed 出版商
Chang J, Baloh R, Milbrandt J. The NIMA-family kinase Nek3 regulates microtubule acetylation in neurons. J Cell Sci. 2009;122:2274-82 pubmed 出版商
Gao D, Inuzuka H, Korenjak M, Tseng A, Wu T, Wan L, et al. Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways. Mol Biol Cell. 2009;20:3305-16 pubmed 出版商
Kingeter L, Schaefer B. Expanding the multicolor capabilities of basic confocal microscopes by employing red and near-infrared quantum dot conjugates. BMC Biotechnol. 2009;9:49 pubmed 出版商
Casas F, Pessemesse L, Grandemange S, Seyer P, Baris O, Gueguen N, et al. Overexpression of the mitochondrial T3 receptor induces skeletal muscle atrophy during aging. PLoS ONE. 2009;4:e5631 pubmed 出版商
Liao Y, Wei Y, Zhou X, Yang J, Dai C, Chen Y, et al. Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation. Oncogene. 2009;28:2436-45 pubmed 出版商
Baus D, Nonnenmacher F, Jankowski S, Doring C, Brautigam C, Frank M, et al. STAT6 and STAT1 are essential antagonistic regulators of cell survival in classical Hodgkin lymphoma cell line. Leukemia. 2009;23:1885-93 pubmed 出版商
Cochrane D, Spoelstra N, Howe E, Nordeen S, Richer J. MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents. Mol Cancer Ther. 2009;8:1055-66 pubmed 出版商
Kostan J, Gregor M, Walko G, Wiche G. Plectin isoform-dependent regulation of keratin-integrin alpha6beta4 anchorage via Ca2+/calmodulin. J Biol Chem. 2009;284:18525-36 pubmed 出版商
Schimanski C, Frerichs K, Rahman F, Berger M, Lang H, Galle P, et al. High miR-196a levels promote the oncogenic phenotype of colorectal cancer cells. World J Gastroenterol. 2009;15:2089-96 pubmed
Wittkopp N, Huntzinger E, Weiler C, Sauliere J, Schmidt S, Sonawane M, et al. Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival. Mol Cell Biol. 2009;29:3517-28 pubmed 出版商
Trompouki E, Tsagaratou A, Kosmidis S, Dolle P, Qian J, Kontoyiannis D, et al. Truncation of the catalytic domain of the cylindromatosis tumor suppressor impairs lung maturation. Neoplasia. 2009;11:469-76 pubmed
Gao Y, Wang B, Xiao Z, Chen B, Han J, Wang X, et al. Nogo-66 regulates nanog expression through stat3 pathway in murine embryonic stem cells. Stem Cells Dev. 2010;19:53-60 pubmed 出版商
Johnson J, Lu C, Raharjo E, McNally K, McNally F, Mains P. Levels of the ubiquitin ligase substrate adaptor MEL-26 are inversely correlated with MEI-1/katanin microtubule-severing activity during both meiosis and mitosis. Dev Biol. 2009;330:349-57 pubmed 出版商
Yagi T, Uematsu K, Liu Z, Kamiya R. Identification of dyneins that localize exclusively to the proximal portion of Chlamydomonas flagella. J Cell Sci. 2009;122:1306-14 pubmed 出版商
Guo Y, Schoell M, Freeman R. The von Hippel-Lindau protein sensitizes renal carcinoma cells to apoptotic stimuli through stabilization of BIM(EL). Oncogene. 2009;28:1864-74 pubmed 出版商
Chekulaeva M, Filipowicz W, Parker R. Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila. RNA. 2009;15:794-803 pubmed 出版商
Naughton R, Quiney C, Turner S, Cotter T. Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway. Leukemia. 2009;23:1432-40 pubmed 出版商
Alazard Dany N, Nicolas A, Ploquin A, Strasser R, Greco A, Epstein A, et al. Definition of herpes simplex virus type 1 helper activities for adeno-associated virus early replication events. PLoS Pathog. 2009;5:e1000340 pubmed 出版商
Hontz R, Niederer R, Johnson J, Smith J. Genetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae. Genetics. 2009;182:105-19 pubmed 出版商
Chartier A, Raz V, Sterrenburg E, Verrips C, van der Maarel S, Simonelig M. Prevention of oculopharyngeal muscular dystrophy by muscular expression of Llama single-chain intrabodies in vivo. Hum Mol Genet. 2009;18:1849-59 pubmed 出版商
Rudinskiy N, Grishchuk Y, Vaslin A, Puyal J, Delacourte A, Hirling H, et al. Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration. J Biol Chem. 2009;284:12447-58 pubmed 出版商
Sánchez Cañete M, Carvalho L, Pérez Victoria F, Gamarro F, Castanys S. Low plasma membrane expression of the miltefosine transport complex renders Leishmania braziliensis refractory to the drug. Antimicrob Agents Chemother. 2009;53:1305-13 pubmed 出版商
Sotiriou E, Vassilatis D, Vila M, Stefanis L. Selective noradrenergic vulnerability in α-synuclein transgenic mice. Neurobiol Aging. 2010;31:2103-14 pubmed 出版商
Rounbehler R, Li W, Hall M, Yang C, Fallahi M, Cleveland J. Targeting ornithine decarboxylase impairs development of MYCN-amplified neuroblastoma. Cancer Res. 2009;69:547-53 pubmed 出版商
de Jesus Perez V, Alastalo T, Wu J, Axelrod J, Cooke J, Amieva M, et al. Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. J Cell Biol. 2009;184:83-99 pubmed 出版商
Asp P, Acosta Alvear D, Tsikitis M, van Oevelen C, Dynlacht B. E2f3b plays an essential role in myogenic differentiation through isoform-specific gene regulation. Genes Dev. 2009;23:37-53 pubmed 出版商
Pai C, Garcia I, Wang S, Cotterill S, MacNeill S, Kearsey S. GINS inactivation phenotypes reveal two pathways for chromatin association of replicative alpha and epsilon DNA polymerases in fission yeast. Mol Biol Cell. 2009;20:1213-22 pubmed 出版商
Norris A, Bianchet M, Boeke J. Compensatory interactions between Sir3p and the nucleosomal LRS surface imply their direct interaction. PLoS Genet. 2008;4:e1000301 pubmed 出版商
Schnoor M, Betanzos A, Weber D, Parkos C. Guanylate-binding protein-1 is expressed at tight junctions of intestinal epithelial cells in response to interferon-gamma and regulates barrier function through effects on apoptosis. Mucosal Immunol. 2009;2:33-42 pubmed 出版商
Cohn M, Kee Y, Haas W, Gygi S, D Andrea A. UAF1 is a subunit of multiple deubiquitinating enzyme complexes. J Biol Chem. 2009;284:5343-51 pubmed 出版商
Yi X, de Vries H, Siudeja K, Rana A, Lemstra W, Brunsting J, et al. Stwl modifies chromatin compaction and is required to maintain DNA integrity in the presence of perturbed DNA replication. Mol Biol Cell. 2009;20:983-94 pubmed 出版商
Lagresle Peyrou C, Six E, Picard C, Rieux Laucat F, Michel V, Ditadi A, et al. Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness. Nat Genet. 2009;41:106-11 pubmed 出版商
Wang F, Tong Q. SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARgamma. Mol Biol Cell. 2009;20:801-8 pubmed 出版商
Seoane M, Iglesias P, Gonzalez T, Dominguez F, Fraga M, Aliste C, et al. Retinoblastoma loss modulates DNA damage response favoring tumor progression. PLoS ONE. 2008;3:e3632 pubmed 出版商
Ayala Y, Zago P, D Ambrogio A, Xu Y, Petrucelli L, Buratti E, et al. Structural determinants of the cellular localization and shuttling of TDP-43. J Cell Sci. 2008;121:3778-85 pubmed 出版商
Di Certo M, Batassa E, Casella I, Serafino A, Floridi A, Passananti C, et al. Delayed internalization and lack of recycling in a beta2-adrenergic receptor fused to the G protein alpha-subunit. BMC Cell Biol. 2008;9:56 pubmed 出版商
Polytarchou C, Pfau R, Hatziapostolou M, Tsichlis P. The JmjC domain histone demethylase Ndy1 regulates redox homeostasis and protects cells from oxidative stress. Mol Cell Biol. 2008;28:7451-64 pubmed 出版商
Rodriguez M, Aladowicz E, Lanfrancone L, Goding C. Tbx3 represses E-cadherin expression and enhances melanoma invasiveness. Cancer Res. 2008;68:7872-81 pubmed 出版商
Krattinger N, Alonso F, Capponi A, Mazzolai L, Nicod P, Meda P, et al. Increased expression of renal cyclooxygenase-2 and neuronal nitric oxide synthase in hypertensive Cx40-deficient mice. J Vasc Res. 2009;46:188-98 pubmed 出版商
Dickson M, Tian X, Liu X, Davis D, Sigmund C. Upstream stimulatory factor is required for human angiotensinogen expression and differential regulation by the A-20C polymorphism. Circ Res. 2008;103:940-7 pubmed 出版商
Saini Y, Harkema J, LaPres J. HIF1alpha is essential for normal intrauterine differentiation of alveolar epithelium and surfactant production in the newborn lung of mice. J Biol Chem. 2008;283:33650-7 pubmed 出版商
Cao W, Aghajanian H, Haig Ladewig L, Gerton G. Sorbitol can fuel mouse sperm motility and protein tyrosine phosphorylation via sorbitol dehydrogenase. Biol Reprod. 2009;80:124-33 pubmed 出版商
Ajduk A, Ciemerych M, Nixon V, Swann K, Maleszewski M. Fertilization differently affects the levels of cyclin B1 and M-phase promoting factor activity in maturing and metaphase II mouse oocytes. Reproduction. 2008;136:741-52 pubmed 出版商
Morelli M, Barberi M, Gambardella A, Borini A, Cecconi S, Coticchio G, et al. Characterization, expression, and functional activity of pituitary adenylate cyclase-activating polypeptide and its receptors in human granulosa-luteal cells. J Clin Endocrinol Metab. 2008;93:4924-32 pubmed 出版商
Fujita N, Hayashi Nishino M, Fukumoto H, Omori H, Yamamoto A, Noda T, et al. An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure. Mol Biol Cell. 2008;19:4651-9 pubmed 出版商
Kaiser C, Dobrikova E, Bradrick S, Shveygert M, Herbert J, Gromeier M. Activation of cap-independent translation by variant eukaryotic initiation factor 4G in vivo. RNA. 2008;14:2170-82 pubmed 出版商
Liu H, Jia Z, Jia Z, Soodvilai S, Guan G, Wang M, et al. Nitro-oleic acid protects the mouse kidney from ischemia and reperfusion injury. Am J Physiol Renal Physiol. 2008;295:F942-9 pubmed 出版商
Schneekloth A, Pucheault M, Tae H, Crews C. Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomics. Bioorg Med Chem Lett. 2008;18:5904-8 pubmed 出版商
Pinto B, Wilmington S, Hornick E, Wallrath L, Geyer P. Tissue-specific defects are caused by loss of the Drosophila MAN1 LEM domain protein. Genetics. 2008;180:133-45 pubmed 出版商
Brandon M, Pennington J, Isoe J, Zamora J, Schillinger A, Miesfeld R. TOR signaling is required for amino acid stimulation of early trypsin protein synthesis in the midgut of Aedes aegypti mosquitoes. Insect Biochem Mol Biol. 2008;38:916-22 pubmed 出版商
Chen Q, Xiong X, Lee T, Liu Y, Wetsel W, Zhang X. Neural plasticity and addiction: integrin-linked kinase and cocaine behavioral sensitization. J Neurochem. 2008;107:679-89 pubmed 出版商
Zovoilis A, Nolte J, Drusenheimer N, Zechner U, Hada H, Guan K, et al. Multipotent adult germline stem cells and embryonic stem cells have similar microRNA profiles. Mol Hum Reprod. 2008;14:521-9 pubmed 出版商
Mannava S, Grachtchouk V, Wheeler L, Im M, Zhuang D, Slavina E, et al. Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells. Cell Cycle. 2008;7:2392-400 pubmed
Miyagi E, Schwartzkopff F, Plishka R, Buckler White A, Clouse K, Strebel K. APOBEC3G-independent reduction in virion infectivity during long-term HIV-1 replication in terminally differentiated macrophages. Virology. 2008;379:266-74 pubmed 出版商
Gómez A, Galleguillos D, Maass J, Battaglioli E, Kukuljan M, Andrés M. CoREST represses the heat shock response mediated by HSF1. Mol Cell. 2008;31:222-31 pubmed 出版商
Kawasaki K, Watanabe M, Sakaguchi M, Ogasawara Y, Ochiai K, Nasu Y, et al. REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer. Cancer Gene Ther. 2009;16:65-72 pubmed 出版商
Dow L, Elsum I, King C, Kinross K, Richardson H, Humbert P. Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling. Oncogene. 2008;27:5988-6001 pubmed 出版商
Mori Y, Koike M, Moriishi E, Kawabata A, Tang H, Oyaizu H, et al. Human herpesvirus-6 induces MVB formation, and virus egress occurs by an exosomal release pathway. Traffic. 2008;9:1728-42 pubmed 出版商
Ding H, Dolan P, Johnson G. Histone deacetylase 6 interacts with the microtubule-associated protein tau. J Neurochem. 2008;106:2119-30 pubmed 出版商
Rai R, Phadnis A, Haralkar S, Badwe R, Dai H, Li K, et al. Differential regulation of centrosome integrity by DNA damage response proteins. Cell Cycle. 2008;7:2225-33 pubmed
Nielsen S, Møllgård K, Clement C, Veland I, Awan A, Yoder B, et al. Characterization of primary cilia and Hedgehog signaling during development of the human pancreas and in human pancreatic duct cancer cell lines. Dev Dyn. 2008;237:2039-52 pubmed 出版商
Burnette D, Ji L, Schaefer A, Medeiros N, Danuser G, Forscher P. Myosin II activity facilitates microtubule bundling in the neuronal growth cone neck. Dev Cell. 2008;15:163-9 pubmed 出版商
Strumane K, Rygiel T, van der Valk M, Collard J. Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice. J Cancer Res Clin Oncol. 2009;135:69-80 pubmed 出版商
Murphy L, Wilkerson D, Hong Y, Sarge K. PRC1 associates with the hsp70i promoter and interacts with HSF2 during mitosis. Exp Cell Res. 2008;314:2224-30 pubmed 出版商
Whelan S, Lane M, Hart G. Regulation of the O-linked beta-N-acetylglucosamine transferase by insulin signaling. J Biol Chem. 2008;283:21411-7 pubmed 出版商
Nakamura N, Miranda Vizuete A, Miki K, Mori C, Eddy E. Cleavage of disulfide bonds in mouse spermatogenic cell-specific type 1 hexokinase isozyme is associated with increased hexokinase activity and initiation of sperm motility. Biol Reprod. 2008;79:537-45 pubmed 出版商
Strasser M, Mackenzie N, Dumstrei K, Nakkrasae L, Stebler J, Raz E. Control over the morphology and segregation of Zebrafish germ cell granules during embryonic development. BMC Dev Biol. 2008;8:58 pubmed 出版商
Pispa J, Palmén S, Holmberg C, Jantti J. C. elegans dss-1 is functionally conserved and required for oogenesis and larval growth. BMC Dev Biol. 2008;8:51 pubmed 出版商
Benoit P, Papin C, Kwak J, Wickens M, Simonelig M. PAP- and GLD-2-type poly(A) polymerases are required sequentially in cytoplasmic polyadenylation and oogenesis in Drosophila. Development. 2008;135:1969-79 pubmed 出版商
Cui J, Sackton K, Horner V, Kumar K, Wolfner M. Wispy, the Drosophila homolog of GLD-2, is required during oogenesis and egg activation. Genetics. 2008;178:2017-29 pubmed 出版商
Temime Smaali N, Guittat L, Wenner T, Bayart E, Douarre C, Gomez D, et al. Topoisomerase IIIalpha is required for normal proliferation and telomere stability in alternative lengthening of telomeres. EMBO J. 2008;27:1513-24 pubmed 出版商
Tworkowski K, Chakraborty A, Samuelson A, Seger Y, Narita M, Hannon G, et al. Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc. Proc Natl Acad Sci U S A. 2008;105:6103-8 pubmed 出版商
Westbroek W, Tuchman M, Tinloy B, De Wever O, Vilboux T, Hertz J, et al. A novel missense mutation (G43S) in the switch I region of Rab27A causing Griscelli syndrome. Mol Genet Metab. 2008;94:248-54 pubmed 出版商
Elsherif L, Huang M, Shai S, Yang Y, Li R, Chun J, et al. Combined deficiency of dystrophin and beta1 integrin in the cardiac myocyte causes myocardial dysfunction, fibrosis and calcification. Circ Res. 2008;102:1109-17 pubmed 出版商
Fujita N, Itoh T, Omori H, Fukuda M, Noda T, Yoshimori T. The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell. 2008;19:2092-100 pubmed 出版商
Ayala Y, Misteli T, Baralle F. TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression. Proc Natl Acad Sci U S A. 2008;105:3785-9 pubmed 出版商
Tanaka M, Jin G, Yamazaki Y, Takahara T, Takuwa M, Nakamura T. Identification of candidate cooperative genes of the Apc mutation in transformation of the colon epithelial cell by retroviral insertional mutagenesis. Cancer Sci. 2008;99:979-85 pubmed 出版商
Laoukili J, Alvarez M, Meijer L, Stahl M, Mohammed S, Kleij L, et al. Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain. Mol Cell Biol. 2008;28:3076-87 pubmed 出版商
Famulski J, Vos L, Sun X, Chan G. Stable hZW10 kinetochore residency, mediated by hZwint-1 interaction, is essential for the mitotic checkpoint. J Cell Biol. 2008;180:507-20 pubmed 出版商
Wahrle S, Jiang H, Parsadanian M, Kim J, Li A, Knoten A, et al. Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease. J Clin Invest. 2008;118:671-82 pubmed 出版商
Kamachi Y, Okuda Y, Kondoh H. Quantitative assessment of the knockdown efficiency of morpholino antisense oligonucleotides in zebrafish embryos using a luciferase assay. Genesis. 2008;46:1-7 pubmed 出版商
Kitagawa Y, Kameoka M, Shoji Kawata S, Iwabu Y, Mizuta H, Tokunaga K, et al. Inhibitory function of adapter-related protein complex 2 alpha 1 subunit in the process of nuclear translocation of human immunodeficiency virus type 1 genome. Virology. 2008;373:171-80 pubmed 出版商
Goemans C, Boya P, Skirrow C, Tolkovsky A. Intra-mitochondrial degradation of Tim23 curtails the survival of cells rescued from apoptosis by caspase inhibitors. Cell Death Differ. 2008;15:545-54 pubmed 出版商
Hutt K, Shi Z, Albertini D, Petroff B. The environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin disrupts morphogenesis of the rat pre-implantation embryo. BMC Dev Biol. 2008;8:1 pubmed 出版商
O Driscoll C, O Connor J, O Brien C, Cotter T. Basic fibroblast growth factor-induced protection from light damage in the mouse retina in vivo. J Neurochem. 2008;105:524-36 pubmed
Kramer O, Müller S, Buchwald M, Reichardt S, Heinzel T. Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha. FASEB J. 2008;22:1369-79 pubmed
Cann G, Guignabert C, Ying L, Deshpande N, Bekker J, Wang L, et al. Developmental expression of LC3alpha and beta: absence of fibronectin or autophagy phenotype in LC3beta knockout mice. Dev Dyn. 2008;237:187-95 pubmed
Lajoie Mazenc I, Tovar D, Penary M, Lortal B, Allart S, Favard C, et al. MAP1A light chain-2 interacts with GTP-RhoB to control epidermal growth factor (EGF)-dependent EGF receptor signaling. J Biol Chem. 2008;283:4155-64 pubmed
Arakawa Y, Cordeiro J, Way M. F11L-mediated inhibition of RhoA-mDia signaling stimulates microtubule dynamics during vaccinia virus infection. Cell Host Microbe. 2007;1:213-26 pubmed
Bouchard C, Lee S, Paulus Hock V, Loddenkemper C, Eilers M, Schmitt C. FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf. Genes Dev. 2007;21:2775-87 pubmed
Payeli S, Schiene Fischer C, Steffel J, Camici G, Rozenberg I, Luscher T, et al. Cyclophilin A differentially activates monocytes and endothelial cells: role of purity, activity, and endotoxin contamination in commercial preparations. Atherosclerosis. 2008;197:564-71 pubmed
Vickers T, Lima W, Nichols J, Crooke S. Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells. Nucleic Acids Res. 2007;35:6598-610 pubmed
Ripper D, Schwarz H, Stierhof Y. Cryo-section immunolabelling of difficult to preserve specimens: advantages of cryofixation, freeze-substitution and rehydration. Biol Cell. 2008;100:109-23 pubmed
Schüller U, Zhao Q, Godinho S, Heine V, Medema R, Pellman D, et al. Forkhead transcription factor FoxM1 regulates mitotic entry and prevents spindle defects in cerebellar granule neuron precursors. Mol Cell Biol. 2007;27:8259-70 pubmed
Williams B, Bateman J, Novikov N, Wu C. Disruption of topoisomerase II perturbs pairing in drosophila cell culture. Genetics. 2007;177:31-46 pubmed
Dokainish H, Gavicherla B, Shen Y, Ireton K. The carboxyl-terminal SH3 domain of the mammalian adaptor CrkII promotes internalization of Listeria monocytogenes through activation of host phosphoinositide 3-kinase. Cell Microbiol. 2007;9:2497-516 pubmed
Boyault C, Zhang Y, Fritah S, Caron C, Gilquin B, Kwon S, et al. HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates. Genes Dev. 2007;21:2172-81 pubmed
Meyers J, Taverna J, Chaves J, Makkinje A, Lerner A. Phosphodiesterase 4 inhibitors augment levels of glucocorticoid receptor in B cell chronic lymphocytic leukemia but not in normal circulating hematopoietic cells. Clin Cancer Res. 2007;13:4920-7 pubmed
Causeret F, Jacobs T, Terao M, Heath O, Hoshino M, Nikolic M. Neurabin-I is phosphorylated by Cdk5: implications for neuronal morphogenesis and cortical migration. Mol Biol Cell. 2007;18:4327-42 pubmed
Moniz S, Verissimo F, Matos P, Brazão R, Silva E, Kotelevets L, et al. Protein kinase WNK2 inhibits cell proliferation by negatively modulating the activation of MEK1/ERK1/2. Oncogene. 2007;26:6071-81 pubmed
Barberi M, Muciaccia B, Morelli M, Stefanini M, Cecconi S, Canipari R. Expression localisation and functional activity of pituitary adenylate cyclase-activating polypeptide, vasoactive intestinal polypeptide and their receptors in mouse ovary. Reproduction. 2007;134:281-92 pubmed
Werner H, Kuhlmann K, Shen S, Uecker M, Schardt A, Dimova K, et al. Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. J Neurosci. 2007;27:7717-30 pubmed
Sekine K, Chen Y, Kojima N, Ogata K, Fukamizu A, Miyajima A. Foxo1 links insulin signaling to C/EBPalpha and regulates gluconeogenesis during liver development. EMBO J. 2007;26:3607-15 pubmed
Sodek K, Ringuette M, Brown T. MT1-MMP is the critical determinant of matrix degradation and invasion by ovarian cancer cells. Br J Cancer. 2007;97:358-67 pubmed
Kurosu T, Hernandez A, Schwartz J. Serotonin induces selective cleavage of the PKA RI subunit but not RII subunit in Aplysia neurons. Biochem Biophys Res Commun. 2007;359:563-7 pubmed
Lu B, Gong Z, Wang J, Zhang J, Liang J. Microtubule dynamics in relation to osmotic stress-induced ABA accumulation in Zea mays roots. J Exp Bot. 2007;58:2565-72 pubmed
Wang F, Nguyen M, Qin F, Tong Q. SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction. Aging Cell. 2007;6:505-14 pubmed
Finzi A, Orthwein A, Mercier J, Cohen E. Productive human immunodeficiency virus type 1 assembly takes place at the plasma membrane. J Virol. 2007;81:7476-90 pubmed
Nelson R, Glenn K, Zhang Y, Wen H, Knutson T, Gouvion C, et al. Selective cochlear degeneration in mice lacking the F-box protein, Fbx2, a glycoprotein-specific ubiquitin ligase subunit. J Neurosci. 2007;27:5163-71 pubmed
Fung M, Cheung H, Wong H, Yuen H, Ling M, Chan K, et al. MAD2 expression and its significance in mitotic checkpoint control in testicular germ cell tumour. Biochim Biophys Acta. 2007;1773:821-32 pubmed
Chen J, Lee C, Errico S, Becker K, Freed W. Increases in expression of 14-3-3 eta and 14-3-3 zeta transcripts during neuroprotection induced by delta9-tetrahydrocannabinol in AF5 cells. J Neurosci Res. 2007;85:1724-33 pubmed
Momose I, Iijima M, Kawada M, Ikeda D. A new proteasome inhibitor, TP-110, induces apoptosis in human prostate cancer PC-3 cells. Biosci Biotechnol Biochem. 2007;71:1036-43 pubmed
Cui H, Hu B, Li T, Ma J, Alam G, Gunning W, et al. Bmi-1 is essential for the tumorigenicity of neuroblastoma cells. Am J Pathol. 2007;170:1370-8 pubmed
Rezniczek G, Konieczny P, Nikolic B, Reipert S, Schneller D, Abrahamsberg C, et al. Plectin 1f scaffolding at the sarcolemma of dystrophic (mdx) muscle fibers through multiple interactions with beta-dystroglycan. J Cell Biol. 2007;176:965-77 pubmed
Mavrakis K, Andrew R, Lee K, Petropoulou C, Dixon J, Navaratnam N, et al. Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover. PLoS Biol. 2007;5:e67 pubmed
Lartey J, Smith M, Pawade J, Strachan B, Mellor H, Lopez Bernal A. Up-regulation of myometrial RHO effector proteins (PKN1 and DIAPH1) and CPI-17 (PPP1R14A) phosphorylation in human pregnancy is associated with increased GTP-RHOA in spontaneous preterm labor. Biol Reprod. 2007;76:971-82 pubmed
Robert A, Margall Ducos G, Guidotti J, Bregerie O, Celati C, Brechot C, et al. The intraflagellar transport component IFT88/polaris is a centrosomal protein regulating G1-S transition in non-ciliated cells. J Cell Sci. 2007;120:628-37 pubmed
Milovic Holm K, Krieghoff E, Jensen K, Will H, Hofmann T. FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies. EMBO J. 2007;26:391-401 pubmed
Solt L, Madge L, Orange J, May M. Interleukin-1-induced NF-kappaB activation is NEMO-dependent but does not require IKKbeta. J Biol Chem. 2007;282:8724-33 pubmed
Oricchio E, Sciamanna I, Beraldi R, Tolstonog G, Schumann G, Spadafora C. Distinct roles for LINE-1 and HERV-K retroelements in cell proliferation, differentiation and tumor progression. Oncogene. 2007;26:4226-33 pubmed
Crepaldi T, Bersani F, Scuoppo C, Accornero P, Prunotto C, Taulli R, et al. Conditional activation of MET in differentiated skeletal muscle induces atrophy. J Biol Chem. 2007;282:6812-22 pubmed
Lawrence C, Maekawa H, Worthington J, Reiter W, Wilkinson C, Jones N. Regulation of Schizosaccharomyces pombe Atf1 protein levels by Sty1-mediated phosphorylation and heterodimerization with Pcr1. J Biol Chem. 2007;282:5160-70 pubmed
Shimazu T, Horinouchi S, Yoshida M. Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing. J Biol Chem. 2007;282:4470-8 pubmed
Boeras D, Granic A, Padmanabhan J, Crespo N, Rojiani A, Potter H. Alzheimer's presenilin 1 causes chromosome missegregation and aneuploidy. Neurobiol Aging. 2008;29:319-28 pubmed
Rujano M, Bosveld F, Salomons F, Dijk F, van Waarde M, van der Want J, et al. Polarised asymmetric inheritance of accumulated protein damage in higher eukaryotes. PLoS Biol. 2006;4:e417 pubmed
Miettinen P, Ustinov J, Ormio P, Gao R, Palgi J, Hakonen E, et al. Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth. Diabetes. 2006;55:3299-308 pubmed
Knauer S, Kramer O, Knösel T, Engels K, Rodel F, Kovacs A, et al. Nuclear export is essential for the tumor-promoting activity of survivin. FASEB J. 2007;21:207-16 pubmed
Ralph E, Boye E, Kearsey S. DNA damage induces Cdt1 proteolysis in fission yeast through a pathway dependent on Cdt2 and Ddb1. EMBO Rep. 2006;7:1134-9 pubmed
Beardsley A, Robertson D, O Donnell L. A complex containing alpha6beta1-integrin and phosphorylated focal adhesion kinase between Sertoli cells and elongated spermatids during spermatid release from the seminiferous epithelium. J Endocrinol. 2006;190:759-70 pubmed
Schlief M, West T, Craig A, Holtzman D, Gitlin J. Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity. Proc Natl Acad Sci U S A. 2006;103:14919-24 pubmed
Lee H, Overall C, McCulloch C, Sodek J. A critical role for the membrane-type 1 matrix metalloproteinase in collagen phagocytosis. Mol Biol Cell. 2006;17:4812-26 pubmed
Leak R, Liou A, Zigmond M. Effect of sublethal 6-hydroxydopamine on the response to subsequent oxidative stress in dopaminergic cells: evidence for preconditioning. J Neurochem. 2006;99:1151-63 pubmed
An H, Maeng O, Kang K, Lee J, Kim Y, Paik S, et al. Activation of Ras up-regulates pro-apoptotic BNIP3 in nitric oxide-induced cell death. J Biol Chem. 2006;281:33939-48 pubmed
Sorin M, Yung E, Wu X, Kalpana G. HIV-1 replication in cell lines harboring INI1/hSNF5 mutations. Retrovirology. 2006;3:56 pubmed
Tian G, Huang M, Parvari R, Diaz G, Cowan N. Cryptic out-of-frame translational initiation of TBCE rescues tubulin formation in compound heterozygous HRD. Proc Natl Acad Sci U S A. 2006;103:13491-6 pubmed
Vercammen L, Van der Perren A, Vaudano E, Gijsbers R, Debyser Z, Van den Haute C, et al. Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease. Mol Ther. 2006;14:716-23 pubmed
Clements D, Mayer R, Johnson S. Subcellular distribution of the TSC2 gene product tuberin in human airway smooth muscle cells is driven by multiple localization sequences and is cell-cycle dependent. Am J Physiol Lung Cell Mol Physiol. 2007;292:L258-66 pubmed
Tsuji T, Ficarro S, Jiang W. Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells. Mol Biol Cell. 2006;17:4459-72 pubmed
Song Y, Lee Y, Narasimhan P, Chan P. Reduced oxidative stress promotes NF-kappaB-mediated neuroprotective gene expression after transient focal cerebral ischemia: lymphocytotrophic cytokines and antiapoptotic factors. J Cereb Blood Flow Metab. 2007;27:764-75 pubmed
Russo A, Magro P, Hu Z, Li W, Peters R, Mandola J, et al. E2F-1 overexpression in U2OS cells increases cyclin B1 levels and cdc2 kinase activity and sensitizes cells to antimitotic agents. Cancer Res. 2006;66:7253-60 pubmed
Wallace D, Donovan M, Cotter T. Histone deacetylase activity regulates apaf-1 and caspase 3 expression in the developing mouse retina. Invest Ophthalmol Vis Sci. 2006;47:2765-72 pubmed
Le Boeuf F, Houle F, Sussman M, Huot J. Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2-mediated phosphorylation of FAK on Tyr407 in response to vascular endothelial growth factor. Mol Biol Cell. 2006;17:3508-20 pubmed
Parra M, Gómez R, Viera A, Page J, Calvente A, Wordeman L, et al. A perikinetochoric ring defined by MCAK and Aurora-B as a novel centromere domain. PLoS Genet. 2006;2:e84 pubmed
Germano S, Barberis D, Santoro M, Penengo L, Citri A, Yarden Y, et al. Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling. J Biol Chem. 2006;281:21710-9 pubmed
Pastuglia M, Azimzadeh J, Goussot M, Camilleri C, Belcram K, Evrard J, et al. Gamma-tubulin is essential for microtubule organization and development in Arabidopsis. Plant Cell. 2006;18:1412-25 pubmed
Catizone A, Ricci G, Del Bravo J, Galdieri M. Hepatocyte growth factor modulates in vitro survival and proliferation of germ cells during postnatal testis development. J Endocrinol. 2006;189:137-46 pubmed
Pereira P, Teixeira A, Pinho S, Ferreira P, Fernandes J, Oliveira C, et al. E-cadherin missense mutations, associated with hereditary diffuse gastric cancer (HDGC) syndrome, display distinct invasive behaviors and genetic interactions with the Wnt and Notch pathways in Drosophila epithelia. Hum Mol Genet. 2006;15:1704-12 pubmed
Foster K, McCrary W, Ross J, Wright C. Members of the hSWI/SNF chromatin remodeling complex associate with and are phosphorylated by protein kinase B/Akt. Oncogene. 2006;25:4605-12 pubmed
Lartey J, Gampel A, Pawade J, Mellor H, Bernal A. Expression of RND proteins in human myometrium. Biol Reprod. 2006;75:452-61 pubmed
Geoffroy M, Chadeuf G, Orr A, Salvetti A, Everett R. Impact of the interaction between herpes simplex virus type 1 regulatory protein ICP0 and ubiquitin-specific protease USP7 on activation of adeno-associated virus type 2 rep gene expression. J Virol. 2006;80:3650-4 pubmed
Leslie K, Lang C, Devgan G, Azare J, Berishaj M, Gerald W, et al. Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3. Cancer Res. 2006;66:2544-52 pubmed
Verollet C, Colombié N, Daubon T, Bourbon H, Wright M, Raynaud Messina B. Drosophila melanogaster gamma-TuRC is dispensable for targeting gamma-tubulin to the centrosome and microtubule nucleation. J Cell Biol. 2006;172:517-28 pubmed
Ayala Y, Pagani F, Baralle F. TDP43 depletion rescues aberrant CFTR exon 9 skipping. FEBS Lett. 2006;580:1339-44 pubmed
Oliveira J, Colf L, McBride A. Variations in the association of papillomavirus E2 proteins with mitotic chromosomes. Proc Natl Acad Sci U S A. 2006;103:1047-52 pubmed
Moore Carrasco R, Garcia Martinez C, Busquets S, Ametller E, Barreiro E, Lopez Soriano F, et al. The AP-1/CJUN signaling cascade is involved in muscle differentiation: implications in muscle wasting during cancer cachexia. FEBS Lett. 2006;580:691-6 pubmed
Krueger A, Fas S, Giaisi M, Bleumink M, Merling A, Stumpf C, et al. HTLV-1 Tax protects against CD95-mediated apoptosis by induction of the cellular FLICE-inhibitory protein (c-FLIP). Blood. 2006;107:3933-9 pubmed
Aston K, Li G, Hicks B, Sessions B, Pate B, Hammon D, et al. Effect of the time interval between fusion and activation on nuclear state and development in vitro and in vivo of bovine somatic cell nuclear transfer embryos. Reproduction. 2006;131:45-51 pubmed
Cartegni L, Hastings M, Calarco J, de Stanchina E, Krainer A. Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2. Am J Hum Genet. 2006;78:63-77 pubmed
Kamimoto T, Shoji S, Hidvegi T, Mizushima N, Umebayashi K, Perlmutter D, et al. Intracellular inclusions containing mutant alpha1-antitrypsin Z are propagated in the absence of autophagic activity. J Biol Chem. 2006;281:4467-76 pubmed
Choi W, Karim Z, Whiteheart S. Arf6 plays an early role in platelet activation by collagen and convulxin. Blood. 2006;107:3145-52 pubmed
Akins M, Greer C. Cytoskeletal organization of the developing mouse olfactory nerve layer. J Comp Neurol. 2006;494:358-67 pubmed
Alarcon Vargas D, Zhang Z, Agarwal B, Challagulla K, Mani S, Kalpana G. Targeting cyclin D1, a downstream effector of INI1/hSNF5, in rhabdoid tumors. Oncogene. 2006;25:722-34 pubmed
Gill M, Murphy J, Fingeroth J. Functional divergence of Kaposi's sarcoma-associated herpesvirus and related gamma-2 herpesvirus thymidine kinases: novel cytoplasmic phosphoproteins that alter cellular morphology and disrupt adhesion. J Virol. 2005;79:14647-59 pubmed
Stähli B, Greutert H, Mei S, Graf P, Frischknecht K, Stalder M, et al. Absence of histamine-induced nitric oxide release in the human radial artery: implications for vasospasm of coronary artery bypass vessels. Am J Physiol Heart Circ Physiol. 2006;290:H1182-9 pubmed
Ogawa T, Hayashi T, Tokunou M, Nakachi K, Trosko J, Chang C, et al. Suberoylanilide hydroxamic acid enhances gap junctional intercellular communication via acetylation of histone containing connexin 43 gene locus. Cancer Res. 2005;65:9771-8 pubmed
Alonso M, Fueyo J, Shay J, Aldape K, Jiang H, Lee O, et al. Expression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance. J Natl Cancer Inst. 2005;97:1589-600 pubmed
Wong H, Fricker M, Wyttenbach A, Villunger A, Michalak E, Strasser A, et al. Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite. Mol Cell Biol. 2005;25:8732-47 pubmed
Tsikitis M, Zhang Z, Edelman W, Zagzag D, Kalpana G. Genetic ablation of Cyclin D1 abrogates genesis of rhabdoid tumors resulting from Ini1 loss. Proc Natl Acad Sci U S A. 2005;102:12129-34 pubmed
Rushlow W, Seah Y, Belliveau D, Rajakumar N. Changes in calcineurin expression induced in the rat brain by the administration of antipsychotics. J Neurochem. 2005;94:587-96 pubmed
Nishida K, Yamasaki S, Ito Y, Kabu K, Hattori K, Tezuka T, et al. Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane. J Cell Biol. 2005;170:115-26 pubmed
Schulze S, Curio Penny B, Li Y, Imani R, Rydberg L, Geyer P, et al. Molecular genetic analysis of the nested Drosophila melanogaster lamin C gene. Genetics. 2005;171:185-96 pubmed
Yang X, Gregan J, Lindner K, Young H, Kearsey S. Nuclear distribution and chromatin association of DNA polymerase alpha-primase is affected by TEV protease cleavage of Cdc23 (Mcm10) in fission yeast. BMC Mol Biol. 2005;6:13 pubmed
Kim H, Kang J, Yumura S, Walsh C, Cho J, Lee J. De novo formation of basal bodies in Naegleria gruberi: regulation by phosphorylation. J Cell Biol. 2005;169:719-24 pubmed
Hut H, Kampinga H, Sibon O. Hsp70 protects mitotic cells against heat-induced centrosome damage and division abnormalities. Mol Biol Cell. 2005;16:3776-85 pubmed
Yuen C, Sedbrook J, Perrin R, Carroll K, Masson P. Loss-of-function mutations of ROOT HAIR DEFECTIVE3 suppress root waving, skewing, and epidermal cell file rotation in Arabidopsis. Plant Physiol. 2005;138:701-14 pubmed
Jiao W, Lin H, Timmons J, Nagaich A, Ng S, Misteli T, et al. E2F-dependent repression of topoisomerase II regulates heterochromatin formation and apoptosis in cells with melanoma-prone mutation. Cancer Res. 2005;65:4067-77 pubmed
Sciamanna I, Landriscina M, Pittoggi C, Quirino M, Mearelli C, Beraldi R, et al. Inhibition of endogenous reverse transcriptase antagonizes human tumor growth. Oncogene. 2005;24:3923-31 pubmed
Haberman Y, Ziv I, Gorzalczany Y, Fukuda M, Sagi Eisenberg R. Classical protein kinase C(s) regulates targeting of synaptotagmin IX to the endocytic recycling compartment. J Cell Sci. 2005;118:1641-9 pubmed
Basar T, Shen Y, Ireton K. Redundant roles for Met docking site tyrosines and the Gab1 pleckstrin homology domain in InlB-mediated entry of Listeria monocytogenes. Infect Immun. 2005;73:2061-74 pubmed
Waltregny D, Glenisson W, Tran S, North B, Verdin E, Colige A, et al. Histone deacetylase HDAC8 associates with smooth muscle alpha-actin and is essential for smooth muscle cell contractility. FASEB J. 2005;19:966-8 pubmed
Vries R, Bezrookove V, Zuijderduijn L, Kia S, Houweling A, Oruetxebarria I, et al. Cancer-associated mutations in chromatin remodeler hSNF5 promote chromosomal instability by compromising the mitotic checkpoint. Genes Dev. 2005;19:665-70 pubmed
Dong F, Pirbhai M, Xiao Y, Zhong Y, Wu Y, Zhong G. Degradation of the proapoptotic proteins Bik, Puma, and Bim with Bcl-2 domain 3 homology in Chlamydia trachomatis-infected cells. Infect Immun. 2005;73:1861-4 pubmed
Franck N, Le Seyec J, Guguen Guillouzo C, Erdtmann L. Hepatitis C virus NS2 protein is phosphorylated by the protein kinase CK2 and targeted for degradation to the proteasome. J Virol. 2005;79:2700-8 pubmed
Claessens Y, Park S, Dubart Kupperschmitt A, Mariot V, Garrido C, Chretien S, et al. Rescue of early-stage myelodysplastic syndrome-deriving erythroid precursors by the ectopic expression of a dominant-negative form of FADD. Blood. 2005;105:4035-42 pubmed
St Pierre B, Liu X, Kha L, Zhu X, Ryan O, Jiang Z, et al. Conserved and specific functions of mammalian ssu72. Nucleic Acids Res. 2005;33:464-77 pubmed
Chan H, Narita M, Lowe S, Livingston D. The p400 E1A-associated protein is a novel component of the p53 --> p21 senescence pathway. Genes Dev. 2005;19:196-201 pubmed
Miller R, Zhang P, Smith M, Beaulieu V, Paunescu T, Brown D, et al. V-ATPase B1-subunit promoter drives expression of EGFP in intercalated cells of kidney, clear cells of epididymis and airway cells of lung in transgenic mice. Am J Physiol Cell Physiol. 2005;288:C1134-44 pubmed
Komati H, Naro F, Mebarek S, De Arcangelis V, Adamo S, Lagarde M, et al. Phospholipase D is involved in myogenic differentiation through remodeling of actin cytoskeleton. Mol Biol Cell. 2005;16:1232-44 pubmed
Patzke S, Hauge H, Sioud M, Finne E, Sivertsen E, Delabie J, et al. Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization. Oncogene. 2005;24:1159-73 pubmed
Paredes J, Stove C, Stove V, Milanezi F, Van Marck V, Derycke L, et al. P-cadherin is up-regulated by the antiestrogen ICI 182,780 and promotes invasion of human breast cancer cells. Cancer Res. 2004;64:8309-17 pubmed
Orbán Németh Z, Simader H, Badurek S, Trancikova A, Propst F. Microtubule-associated protein 1S, a short and ubiquitously expressed member of the microtubule-associated protein 1 family. J Biol Chem. 2005;280:2257-65 pubmed
Rajabi H, Baluchamy S, Kolli S, Nag A, Srinivas R, Raychaudhuri P, et al. Effects of depletion of CREB-binding protein on c-Myc regulation and cell cycle G1-S transition. J Biol Chem. 2005;280:361-74 pubmed
Strachan L, Condic M. Cranial neural crest recycle surface integrins in a substratum-dependent manner to promote rapid motility. J Cell Biol. 2004;167:545-54 pubmed
Karaca G, Hargett D, McLean T, Aguilar J, Ghazal P, Wagner E, et al. Inhibition of the stress-activated kinase, p38, does not affect the virus transcriptional program of herpes simplex virus type 1. Virology. 2004;329:142-56 pubmed
Zhang J, Shridhar R, Dai Q, Song J, Barlow S, Yin L, et al. Cystatin m: a novel candidate tumor suppressor gene for breast cancer. Cancer Res. 2004;64:6957-64 pubmed
Geoffroy M, Epstein A, Toublanc E, Moullier P, Salvetti A. Herpes simplex virus type 1 ICP0 protein mediates activation of adeno-associated virus type 2 rep gene expression from a latent integrated form. J Virol. 2004;78:10977-86 pubmed
Wang G, Dombkowski A, Chuang L, Xu X. The involvement of XPC protein in the cisplatin DNA damaging treatment-mediated cellular response. Cell Res. 2004;14:303-14 pubmed
Chaplet M, Detry C, Deroanne C, Fisher L, Castronovo V, Bellahcene A. Zoledronic acid up-regulates bone sialoprotein expression in osteoblastic cells through Rho GTPase inhibition. Biochem J. 2004;384:591-8 pubmed
Lachat Y, Diserens A, Nozaki M, Kobayashi H, Hamou M, Godard S, et al. INK4a/Arf is required for suppression of EGFR/DeltaEGFR(2-7)-dependent ERK activation in mouse astrocytes and glioma. Oncogene. 2004;23:6854-63 pubmed
Rahn J, Shen Q, Mah B, Hugh J. MUC1 initiates a calcium signal after ligation by intercellular adhesion molecule-1. J Biol Chem. 2004;279:29386-90 pubmed
Sedbrook J, Ehrhardt D, Fisher S, Scheible W, Somerville C. The Arabidopsis sku6/spiral1 gene encodes a plus end-localized microtubule-interacting protein involved in directional cell expansion. Plant Cell. 2004;16:1506-20 pubmed
Zhang K, Barron T, Turco S, Beverley S. The LPG1 gene family of Leishmania major. Mol Biochem Parasitol. 2004;136:11-23 pubmed
Salasznyk R, Williams W, Boskey A, Batorsky A, Plopper G. Adhesion to Vitronectin and Collagen I Promotes Osteogenic Differentiation of Human Mesenchymal Stem Cells. J Biomed Biotechnol. 2004;2004:24-34 pubmed
Iida S, Hirota T, Morisaki T, Marumoto T, Hara T, Kuninaka S, et al. Tumor suppressor WARTS ensures genomic integrity by regulating both mitotic progression and G1 tetraploidy checkpoint function. Oncogene. 2004;23:5266-74 pubmed
St Pierre B, Cooper M, Jiang Z, Zacksenhaus E, Egan S. Dynamic regulation of the Stra13/Sharp/Dec bHLH repressors in mammary epithelium. Dev Dyn. 2004;230:124-30 pubmed
Corcoran L, Mitchison T, Liu Q. A novel action of histone deacetylase inhibitors in a protein aggresome disease model. Curr Biol. 2004;14:488-92 pubmed
Liu Y, Encinas M, Comella J, Aldea M, Gallego C. Basic helix-loop-helix proteins bind to TrkB and p21(Cip1) promoters linking differentiation and cell cycle arrest in neuroblastoma cells. Mol Cell Biol. 2004;24:2662-72 pubmed
Yanagisawa H, Kamiya R. A tektin homologue is decreased in chlamydomonas mutants lacking an axonemal inner-arm dynein. Mol Biol Cell. 2004;15:2105-15 pubmed
Yung E, Sorin M, Wang E, Perumal S, Ott D, Kalpana G. Specificity of interaction of INI1/hSNF5 with retroviral integrases and its functional significance. J Virol. 2004;78:2222-31 pubmed
Holmfeldt P, Stenmark S, Gullberg M. Differential functional interplay of TOGp/XMAP215 and the KinI kinesin MCAK during interphase and mitosis. EMBO J. 2004;23:627-37 pubmed
Moser M, Li Y, Vaupel K, Kretzschmar D, Kluge R, Glynn P, et al. Placental failure and impaired vasculogenesis result in embryonic lethality for neuropathy target esterase-deficient mice. Mol Cell Biol. 2004;24:1667-79 pubmed
Mingo Sion A, Marietta P, Koller E, Wolf D, Van Den Berg C. Inhibition of JNK reduces G2/M transit independent of p53, leading to endoreduplication, decreased proliferation, and apoptosis in breast cancer cells. Oncogene. 2004;23:596-604 pubmed
Cassimeris L, Morabito J. TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly. Mol Biol Cell. 2004;15:1580-90 pubmed
Sen G, Wehrman T, Myers J, Blau H. Restriction enzyme-generated siRNA (REGS) vectors and libraries. Nat Genet. 2004;36:183-9 pubmed
Young A, Longmore G. Ras protects Rb family null fibroblasts from cell death: a role for AP-1. J Biol Chem. 2004;279:10931-8 pubmed
Yanagisawa M, Kaverina I, Wang A, Fujita Y, Reynolds A, Anastasiadis P. A novel interaction between kinesin and p120 modulates p120 localization and function. J Biol Chem. 2004;279:9512-21 pubmed
Boonsirichai K, Sedbrook J, Chen R, Gilroy S, Masson P. ALTERED RESPONSE TO GRAVITY is a peripheral membrane protein that modulates gravity-induced cytoplasmic alkalinization and lateral auxin transport in plant statocytes. Plant Cell. 2003;15:2612-25 pubmed
Gregan J, Lindner K, Brimage L, Franklin R, Namdar M, Hart E, et al. Fission yeast Cdc23/Mcm10 functions after pre-replicative complex formation to promote Cdc45 chromatin binding. Mol Biol Cell. 2003;14:3876-87 pubmed
Horne M, Guadagno T. A requirement for MAP kinase in the assembly and maintenance of the mitotic spindle. J Cell Biol. 2003;161:1021-8 pubmed
Maxwell C, Keats J, Crainie M, Sun X, Yen T, Shibuya E, et al. RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability. Mol Biol Cell. 2003;14:2262-76 pubmed
Hut H, Lemstra W, Blaauw E, Van Cappellen G, Kampinga H, Sibon O. Centrosomes split in the presence of impaired DNA integrity during mitosis. Mol Biol Cell. 2003;14:1993-2004 pubmed
Ho J, Watts F. Characterization of SUMO-conjugating enzyme mutants in Schizosaccharomyces pombe identifies a dominant-negative allele that severely reduces SUMO conjugation. Biochem J. 2003;372:97-104 pubmed
Roehrich M, Mooser V, Lenain V, Herz J, Nimpf J, Azhar S, et al. Insulin-secreting beta-cell dysfunction induced by human lipoproteins. J Biol Chem. 2003;278:18368-75 pubmed
Swenson K, Winkler K, Means A. A new identity for MLK3 as an NIMA-related, cell cycle-regulated kinase that is localized near centrosomes and influences microtubule organization. Mol Biol Cell. 2003;14:156-72 pubmed
Lu L, Schulz H, Wolf D. The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells. BMC Cell Biol. 2002;3:22 pubmed
Llano M, Kelly T, Vanegas M, Peretz M, Peterson T, Simari R, et al. Blockade of human immunodeficiency virus type 1 expression by caveolin-1. J Virol. 2002;76:9152-64 pubmed
Martin J, Bluhm W, He H, Mestril R, Dillmann W. Mutation of COOH-terminal lysines in overexpressed alpha B-crystallin abrogates ischemic protection in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2002;283:H85-91 pubmed
Crespo N, Delarue F, Ohkanda J, Carrico D, Hamilton A, Sebti S. The farnesyltransferase inhibitor, FTI-2153, inhibits bipolar spindle formation during mitosis independently of transformation and Ras and p53 mutation status. Cell Death Differ. 2002;9:702-9 pubmed
Ferbeyre G, de Stanchina E, Lin A, Querido E, McCurrach M, Hannon G, et al. Oncogenic ras and p53 cooperate to induce cellular senescence. Mol Cell Biol. 2002;22:3497-508 pubmed
Hu K, Roos D, Murray J. A novel polymer of tubulin forms the conoid of Toxoplasma gondii. J Cell Biol. 2002;156:1039-50 pubmed
Lindner K, Gregan J, Montgomery S, Kearsey S. Essential role of MCM proteins in premeiotic DNA replication. Mol Biol Cell. 2002;13:435-44 pubmed
Pandya K, Townes T. Basic residues within the Kruppel zinc finger DNA binding domains are the critical nuclear localization determinants of EKLF/KLF-1. J Biol Chem. 2002;277:16304-12 pubmed
Liang D, Forsburg S. Characterization of Schizosaccharomyces pombe mcm7(+) and cdc23(+) (MCM10) and interactions with replication checkpoints. Genetics. 2001;159:471-86 pubmed
Tanaka K, Hao Z, Kai M, Okayama H. Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism. EMBO J. 2001;20:5779-90 pubmed
Webley S, Welsh S, Jackman A, Aherne G. The ability to accumulate deoxyuridine triphosphate and cellular response to thymidylate synthase (TS) inhibition. Br J Cancer. 2001;85:446-52 pubmed
Adams R, Maiato H, Earnshaw W, Carmena M. Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation. J Cell Biol. 2001;153:865-80 pubmed
Kasahara Y, Tuder R, Cool C, Lynch D, Flores S, Voelkel N. Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am J Respir Crit Care Med. 2001;163:737-44 pubmed
Crespo N, Ohkanda J, Yen T, Hamilton A, Sebti S. The farnesyltransferase inhibitor, FTI-2153, blocks bipolar spindle formation and chromosome alignment and causes prometaphase accumulation during mitosis of human lung cancer cells. J Biol Chem. 2001;276:16161-7 pubmed
Miyake S, Sellers W, Safran M, Li X, Zhao W, Grossman S, et al. Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle. Mol Cell Biol. 2000;20:8889-902 pubmed
Cheng Q, Lee H, Li Y, Parks T, Cheng G. Upregulation of Bcl-x and Bfl-1 as a potential mechanism of chemoresistance, which can be overcome by NF-kappaB inhibition. Oncogene. 2000;19:4936-40 pubmed
Osaka F, Saeki M, Katayama S, Aida N, Toh e A, Kominami K, et al. Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast. EMBO J. 2000;19:3475-84 pubmed
Umino T, Wang H, Zhu Y, Liu X, Manouilova L, Spurzem J, et al. Modification of type I collagenous gels by alveolar epithelial cells. Am J Respir Cell Mol Biol. 2000;22:702-7 pubmed
Hirota T, Morisaki T, Nishiyama Y, Marumoto T, Tada K, Hara T, et al. Zyxin, a regulator of actin filament assembly, targets the mitotic apparatus by interacting with h-warts/LATS1 tumor suppressor. J Cell Biol. 2000;149:1073-86 pubmed
Grandjean V, Smith J, Schofield P, Ferguson Smith A. Increased IGF-II protein affects p57kip2 expression in vivo and in vitro: implications for Beckwith-Wiedemann syndrome. Proc Natl Acad Sci U S A. 2000;97:5279-84 pubmed
Murakami H, Nurse P. Meiotic DNA replication checkpoint control in fission yeast. Genes Dev. 1999;13:2581-93 pubmed
Chen T, Boisvert F, Bazett Jones D, Richard S. A role for the GSG domain in localizing Sam68 to novel nuclear structures in cancer cell lines. Mol Biol Cell. 1999;10:3015-33 pubmed
Myster S, Knott J, Wysocki K, O TOOLE E, Porter M. Domains in the 1alpha dynein heavy chain required for inner arm assembly and flagellar motility in Chlamydomonas. J Cell Biol. 1999;146:801-18 pubmed
Eiserich J, Estevez A, Bamberg T, Ye Y, Chumley P, Beckman J, et al. Microtubule dysfunction by posttranslational nitrotyrosination of alpha-tubulin: a nitric oxide-dependent mechanism of cellular injury. Proc Natl Acad Sci U S A. 1999;96:6365-70 pubmed
Sherman D, Forsburg S. Schizosaccharomyces pombe Mcm3p, an essential nuclear protein, associates tightly with Nda4p (Mcm5p). Nucleic Acids Res. 1998;26:3955-60 pubmed
Sherman D, Pasion S, Forsburg S. Multiple domains of fission yeast Cdc19p (MCM2) are required for its association with the core MCM complex. Mol Biol Cell. 1998;9:1833-45 pubmed
Stern B, Nurse P. Cyclin B proteolysis and the cyclin-dependent kinase inhibitor rum1p are required for pheromone-induced G1 arrest in fission yeast. Mol Biol Cell. 1998;9:1309-21 pubmed
Yamaguchi S, Murakami H, Okayama H. A WD repeat protein controls the cell cycle and differentiation by negatively regulating Cdc2/B-type cyclin complexes. Mol Biol Cell. 1997;8:2475-86 pubmed
Forsburg S, Sherman D, Ottilie S, Yasuda J, Hodson J. Mutational analysis of Cdc19p, a Schizosaccharomyces pombe MCM protein. Genetics. 1997;147:1025-41 pubmed
Baum B, Wuarin J, Nurse P. Control of S-phase periodic transcription in the fission yeast mitotic cycle. EMBO J. 1997;16:4676-88 pubmed
Zhang Q, Magnusson M, Mosher D. Lysophosphatidic acid and microtubule-destabilizing agents stimulate fibronectin matrix assembly through Rho-dependent actin stress fiber formation and cell contraction. Mol Biol Cell. 1997;8:1415-25 pubmed
Rieder C, Khodjakov A, Paliulis L, Fortier T, Cole R, Sluder G. Mitosis in vertebrate somatic cells with two spindles: implications for the metaphase/anaphase transition checkpoint and cleavage. Proc Natl Acad Sci U S A. 1997;94:5107-12 pubmed
Stern B, Nurse P. Fission yeast pheromone blocks S-phase by inhibiting the G1 cyclin B-p34cdc2 kinase. EMBO J. 1997;16:534-44 pubmed
Elefanty A, Antoniou M, Custodio N, Carmo Fonseca M, Grosveld F. GATA transcription factors associate with a novel class of nuclear bodies in erythroblasts and megakaryocytes. EMBO J. 1996;15:319-33 pubmed
LeDizet M, Piperno G. Detection of acetylated alpha-tubulin by specific antibodies. Methods Enzymol. 1991;196:264-74 pubmed
产品信息
Product No. :
T5168
产品名称 :
Monoclonal Anti-α-Tubulin antibody produced in mouse
宿主 :
小鼠
共轭标签 :
未共轭
抗体类型 :
单克隆
Clone Number (if monoclonal) :
B-5-1-2
应用/描述 :
Suitable for indirect immunofluorescence: 1:2,000 using cultured human or chicken fibroblasts; western blot: 1:4,000 using human fibroblast cell extract; radioimmunoassay
物种活性 :
human, Chlamydomonas, African green monkey, chicken, kangaroo rat, bovine, mouse, rat, sea urchin
抗体亚型 :
IgG1
储存 :
存放在-20°C
更多信息或购买 :
公司信息
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http://www.sigmaaldrich.com/china-mainland.html
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