产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
产品类型 :
抗体
产品名称 :
Monoclonal Anti-α-Tubulin antibody produced in mouse
目录 :
T6074
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
B-5-1-2
反应物种 :
fission yeast, 仓鼠, 酵母菌目, 中国人仓鼠, groundhog, 衣藻, 人类, 小鼠, 大鼠, , , fruit fly , 家羊, 非洲爪蛙, 拟南芥, domestic rabbit, roundworm , 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 1064
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:10,000; 图 2f
Urdiciain A, Erausquin E, Zelaya M, Zazpe I, Lanciego J, Melendez B, et al. Silencing of Histone Deacetylase 6 Decreases Cellular Malignancy and Contributes to Primary Cilium Restoration, Epithelial-to-Mesenchymal Transition Reversion, and Autophagy Inhibition in Glioblastoma Cell Lines. Biology (Basel). 2021;10: pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:13,000; 图 s3a
Chenouard N, Xuan F, Tsien R. Synaptic vesicle traffic is supported by transient actin filaments and regulated by PKA and NO. Nat Commun. 2020;11:5318 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3d
Alonso Herranz L, Sahún Español Á, Paredes A, Gonzalo P, Gkontra P, Núñez V, et al. Macrophages promote endothelial-to-mesenchymal transition via MT1-MMP/TGFβ1 after myocardial infarction. elife. 2020;9: pubmed 出版商
  • 免疫沉淀; 人类; 图 1c
Fenech E, Lari F, Charles P, Fischer R, Laétitia Thézénas M, Bagola K, et al. Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Reynders M, Matsuura B, Bérouti M, Simoneschi D, Marzio A, Pagano M, et al. PHOTACs enable optical control of protein degradation. Sci Adv. 2020;6:eaay5064 pubmed 出版商
  • 免疫印迹; 人类; 1:4000; 图 s4f
Ahfeldt T, Ordureau A, Bell C, Sarrafha L, Sun C, Piccinotti S, et al. Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons. Stem Cell Reports. 2020;14:75-90 pubmed 出版商
  • 免疫印迹; roundworm ; 图 10e
Ji J, Yuan J, Guo X, Ji R, Quan Q, Ding M, et al. Harmine suppresses hyper-activated Ras-MAPK pathway by selectively targeting oncogenic mutated Ras/Raf in Caenorhabditis elegans. Cancer Cell Int. 2019;19:159 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b
Ducommun S, Deak M, Zeigerer A, Göransson O, Seitz S, Collodet C, et al. Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates. Cell Signal. 2019;57:45-57 pubmed 出版商
  • 免疫印迹; 人类; 图 5d
Craxton A, Munnur D, Jukes Jones R, Skalka G, Langlais C, Cain K, et al. PAXX and its paralogs synergistically direct DNA polymerase λ activity in DNA repair. Nat Commun. 2018;9:3877 pubmed 出版商
  • 免疫印迹; 人类; 图 2b
Bianchi Smiraglia A, Bagati A, Fink E, Affronti H, Lipchick B, Moparthy S, et al. Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma. J Clin Invest. 2018;128:4682-4696 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Kane M, Rebensburg S, Takata M, Zang T, Yamashita M, Kvaratskhelia M, et al. Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2. elife. 2018;7: pubmed 出版商
  • 免疫细胞化学; 非洲爪蛙; 图 3c
Cagnetta R, Frese C, Shigeoka T, Krijgsveld J, Holt C. Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome. Neuron. 2018;99:29-46.e4 pubmed 出版商
  • 免疫印迹; 人类; 1:4000; 图 s11d
Trepte P, Kruse S, Kostova S, Hoffmann S, Buntru A, Tempelmeier A, et al. LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells. Mol Syst Biol. 2018;14:e8071 pubmed 出版商
  • 免疫组化-冰冻切片; 拟南芥; 1:100; 图 6c
Reipert S, Goldammer H, Richardson C, Goldberg M, Hawkins T, Hollergschwandtner E, et al. Agitation Modules: Flexible Means to Accelerate Automated Freeze Substitution. J Histochem Cytochem. 2018;66:903-921 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Bernal A, Moltó Abad M, Dominguez D, Tusell L. Acute telomere deprotection prevents ongoing BFB cycles and rampant instability in p16INK4a-deficient epithelial cells. Oncotarget. 2018;9:27151-27170 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 ex3g
Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, de Tullio P, et al. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2018;558:605-609 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1c
Gozdecka M, Meduri E, Mazan M, Tzelepis K, Dudek M, Knights A, et al. UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs. Nat Genet. 2018;50:883-894 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s6a
Clemente C, Rius C, Alonso Herranz L, Martín Alonso M, Pollán A, Camafeita E, et al. MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis. Nat Commun. 2018;9:910 pubmed 出版商
  • 免疫印迹; 人类; 图 8
Bartusch C, Döring T, Prange R. Rab33B Controls Hepatitis B Virus Assembly by Regulating Core Membrane Association and Nucleocapsid Processing. Viruses. 2017;9: pubmed 出版商
  • 免疫细胞化学; 人类; 1:2000; 图 1a
Dong C, Xu H, Zhang R, Tanaka N, Takeichi M, Meng W. CAMSAP3 accumulates in the pericentrosomal area and accompanies microtubule release from the centrosome via katanin. J Cell Sci. 2017;130:1709-1715 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:10; 图 5a
  • 免疫组化; 人类; 1:10; 图 3
Grzelak C, Sigglekow N, Tirnitz Parker J, Hamson E, Warren A, Maneck B, et al. Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease. PLoS ONE. 2017;12:e0171480 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3a
Tormos A, Rius Pérez S, Jorques M, Rada P, Ramírez L, Valverde A, et al. p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging. PLoS ONE. 2017;12:e0171738 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Lin J, Kumari S, Kim C, Van T, Wachsmuth L, Polykratis A, et al. RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Nature. 2016;540:124-128 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 2
Vasconcelos F, Sessa A, Laranjeira C, Raposo A, Teixeira V, Hagey D, et al. MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate Neurogenesis. Cell Rep. 2016;17:469-483 pubmed 出版商
  • 免疫印迹; 中国人仓鼠; 1:5000; 图 1
  • 免疫印迹; 人类; 1:5000; 图 2
Qi L, Jafari N, Li X, Chen Z, Li L, Hytönen V, et al. Talin2-mediated traction force drives matrix degradation and cell invasion. J Cell Sci. 2016;129:3661-3674 pubmed
  • 免疫印迹; 小鼠; 1:2000; 图 2
Wolfe S, Workman E, Heaney C, Niere F, Namjoshi S, Cacheaux L, et al. FMRP regulates an ethanol-dependent shift in GABABR function and expression with rapid antidepressant properties. Nat Commun. 2016;7:12867 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 4
Hu H, Umemori H, Hsueh Y. Postsynaptic SDC2 induces transsynaptic signaling via FGF22 for bidirectional synaptic formation. Sci Rep. 2016;6:33592 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1
Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 7
  • 免疫印迹; 小鼠; 1:5000; 图 3
Fern ndez Majada V, Welz P, Ermolaeva M, Schell M, Adam A, Dietlein F, et al. The tumour suppressor CYLD regulates the p53 DNA damage response. Nat Commun. 2016;7:12508 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3a
Li L, Han L, Zhang J, Liu X, Ma R, Hou X, et al. Epsin2 promotes polarity establishment and meiotic division through activating Cdc42 in mouse oocyte. Oncotarget. 2016;7:50927-50936 pubmed 出版商
  • 免疫印迹; 人类; 1:50,000; 图 1
Li L, Shi L, Yang S, Yan R, Zhang D, Yang J, et al. SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability. Nat Commun. 2016;7:12235 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Lu R, Hu X, Zhou J, Sun J, Zhu A, Xu X, et al. COPS5 amplification and overexpression confers tamoxifen-resistance in ER?-positive breast cancer by degradation of NCoR. Nat Commun. 2016;7:12044 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
  • 免疫印迹; 人类; 图 2
Skoge R, Ziegler M. SIRT2 inactivation reveals a subset of hyperacetylated perinuclear microtubules inaccessible to HDAC6. J Cell Sci. 2016;129:2972-82 pubmed 出版商
  • 免疫印迹; 非洲爪蛙; 1:5000; 图 2
Konopacki F, Wong H, Dwivedy A, Bellon A, Blower M, Holt C. ESCRT-II controls retinal axon growth by regulating DCC receptor levels and local protein synthesis. Open Biol. 2016;6:150218 pubmed 出版商
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Nutter C, Jaworski E, Verma S, Deshmukh V, Wang Q, Botvinnik O, et al. Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes. Cell Rep. 2016;15:2200-2213 pubmed 出版商
  • 免疫印迹; fission yeast; 图 5
Ma N, Ma Y, Nakashima A, Kikkawa U, Furuyashiki T. The Loss of Lam2 and Npr2-Npr3 Diminishes the Vacuolar Localization of Gtr1-Gtr2 and Disinhibits TORC1 Activity in Fission Yeast. PLoS ONE. 2016;11:e0156239 pubmed 出版商
  • 免疫印迹; 人类; 1:4000; 图 4
Lopez A, Kugelman J, Garcia Rivera J, Urias E, Salinas S, Fernandez Zapico M, et al. The Structure-Specific Recognition Protein 1 Associates with Lens Epithelium-Derived Growth Factor Proteins and Modulates HIV-1 Replication. J Mol Biol. 2016;428:2814-31 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 2
Ramesh S, Singh A, Cibi D, Hausenloy D, Singh M. In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart. J Vis Exp. 2016;: pubmed 出版商
  • 免疫印迹; 小鼠; 图 s4
Pourcet B, Gage M, León T, Waddington K, Pello O, Steffensen K, et al. The nuclear receptor LXR modulates interleukin-18 levels in macrophages through multiple mechanisms. Sci Rep. 2016;6:25481 pubmed 出版商
  • 免疫印迹; 人类; 图 6
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  • 免疫印迹; 人类; 1:10,000; 图 4
Krall A, Xu S, Graeber T, Braas D, Christofk H. Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. Nat Commun. 2016;7:11457 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Kim S, Choi K, Cho S, Yun S, Jeon J, Koh Y, et al. Fisetin stimulates autophagic degradation of phosphorylated tau via the activation of TFEB and Nrf2 transcription factors. Sci Rep. 2016;6:24933 pubmed 出版商
  • 免疫印迹; 小鼠; 1:25,000; 图 1
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  • 免疫印迹; fruit fly ; 1:10,000; 图 1
Kwenda L, Collins C, Dattoli A, Dunleavy E. Nucleolar activity and CENP-C regulate CENP-A and CAL1 availability for centromere assembly in meiosis. Development. 2016;143:1400-12 pubmed 出版商
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Saito A, Ferhadian D, Sowd G, Serrao E, Shi J, Halambage U, et al. Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74. J Virol. 2016;90:5808-5823 pubmed 出版商
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Chu C, Ossipova O, Ioannou A, Sokol S. Prickle3 synergizes with Wtip to regulate basal body organization and cilia growth. Sci Rep. 2016;6:24104 pubmed 出版商
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Li Y, Liu D, López Paz C, OLSON B, Umen J. A new class of cyclin dependent kinase in Chlamydomonas is required for coupling cell size to cell division. elife. 2016;5:e10767 pubmed 出版商
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Vlantis K, Wullaert A, Polykratis A, Kondylis V, Dannappel M, Schwarzer R, et al. NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions. Immunity. 2016;44:553-567 pubmed 出版商
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Atiq R, Hertz R, Eldad S, Smeir E, Bar Tana J. Suppression of B-Raf(V600E) cancers by MAPK hyper-activation. Oncotarget. 2016;7:18694-704 pubmed 出版商
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Swenson S, Cannon A, Harris N, Taylor N, Fox J, Khalimonchuk O. Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes. J Biol Chem. 2016;291:10411-25 pubmed 出版商
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Moiseeva O, Lopes Paciencia S, Huot G, Lessard F, Ferbeyre G. Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase. Aging (Albany NY). 2016;8:366-81 pubmed
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Ost M, Coleman V, Voigt A, van Schothorst E, Keipert S, van der Stelt I, et al. Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action. Mol Metab. 2016;5:79-90 pubmed 出版商
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Ren C, Yang Y, Sun J, Wu Z, Zhang R, Shen D, et al. Exercise Training Improves the Altered Renin-Angiotensin System in the Rostral Ventrolateral Medulla of Hypertensive Rats. Oxid Med Cell Longev. 2016;2016:7413963 pubmed 出版商
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Kim N, Kim M, Sung P, Bae Y, Shin E, Yoo J. Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A. Nat Commun. 2016;7:10631 pubmed 出版商
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Chen S, Blank M, Iyer A, Huang B, Wang L, Grummt I, et al. SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing. Nat Commun. 2016;7:10734 pubmed 出版商
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Sansó M, Levin R, Lipp J, Wang V, Greifenberg A, Quezada E, et al. P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates. Genes Dev. 2016;30:117-31 pubmed 出版商
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Ghosh A, Ghosh S, Dasgupta D, Ghosh A, Datta S, Sikdar N, et al. Hepatitis B Virus X Protein Upregulates hELG1/ ATAD5 Expression through E2F1 in Hepatocellular Carcinoma. Int J Biol Sci. 2016;12:30-41 pubmed 出版商
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Drusenheimer N, Migdal B, Jäckel S, Tveriakhina L, Scheider K, Schulz K, et al. The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling. PLoS Genet. 2015;11:e1005749 pubmed 出版商
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Dias J, Rito T, Torlai Triglia E, Kukalev A, Ferrai C, Chotalia M, et al. Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells. elife. 2015;4: pubmed 出版商
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Lee E, Jin D, Lee B, Kim Y, Han J, Shim Y, et al. Negative effect of cyclin D1 overexpression on recurrence-free survival in stage II-IIIA lung adenocarcinoma and its expression modulation by vorinostat in vitro. BMC Cancer. 2015;15:982 pubmed 出版商
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Edmonds M, Boyd K, Moyo T, Mitra R, Duszynski R, Arrate M, et al. MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer. J Clin Invest. 2016;126:349-64 pubmed 出版商
  • 免疫细胞化学; 人类; 1:2000; 图 1
Pillai S, Nguyen J, Johnson J, Haura E, Coppola D, Chellappan S. Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis. Nat Commun. 2015;6:10072 pubmed 出版商
  • 免疫印迹; 人类; 0.2 ug/ml; 图 4b
Leclercq A, Veillat V, Loriot S, Spuul P, Madonna F, Roques X, et al. A Methodology for Concomitant Isolation of Intimal and Adventitial Endothelial Cells from the Human Thoracic Aorta. PLoS ONE. 2015;10:e0143144 pubmed 出版商
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Ksionda O, Melton A, Bache J, Tenhagen M, Bakker J, Harvey R, et al. RasGRP1 overexpression in T-ALL increases basal nucleotide exchange on Ras rendering the Ras/PI3K/Akt pathway responsive to protumorigenic cytokines. Oncogene. 2016;35:3658-68 pubmed 出版商
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Tonsing Carter E, Bailey B, Saadatzadeh M, Ding J, Wang H, Sinn A, et al. Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model. Mol Cancer Ther. 2015;14:2850-63 pubmed 出版商
  • 免疫印迹; 家羊; 1:1000; 图 1a
Teng R, Wu T, Afolayan A, Konduri G. Nitrotyrosine impairs mitochondrial function in fetal lamb pulmonary artery endothelial cells. Am J Physiol Cell Physiol. 2016;310:C80-8 pubmed 出版商
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Han L, Ge J, Zhang L, Ma R, Hou X, Li B, et al. Sirt6 depletion causes spindle defects and chromosome misalignment during meiosis of mouse oocyte. Sci Rep. 2015;5:15366 pubmed 出版商
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产品信息
Product No. :
T6074
产品名称 :
Monoclonal Anti-α-Tubulin antibody produced in mouse
宿主 :
小鼠
共轭标签 :
未共轭
抗体类型 :
单克隆
Clone Number (if monoclonal) :
B-5-1-2
应用/描述 :
Suitable for immunocytochemistry: 0.5-1 μg/mL using cultured chicken fibroblasts (CFB); western blot: 0.25-0.5 μg/mL using total cell extract of human foreskin fibroblast cell line (FS11); microarray; immunoprecipitation (IP)
物种活性 :
human, Chlamydomonas, African green monkey, chicken, kangaroo rat, bovine, mouse, rat, sea urchin
抗体亚型 :
IgG1
浓度 :
~2 mg/毫升
储存 :
存放在-20°C
更多信息或购买 :
公司信息
西格玛奥德里奇
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http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
公司总部: 美国
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