Francis V, Alshafie W, Kumar R, Girard M, Brais B, McPherson P. The ARSACS disease protein sacsin controls lysosomal positioning and reformation by regulating microtubule dynamics. J Biol Chem. 2022;298:102320 pubmed 出版商

Ikari S, Yang Q, Lu S, Liu Y, Hao F, Tong G, et al. Quercetin in Tartary Buckwheat Induces Autophagy against Protein Aggregations. Antioxidants (Basel). 2021;10: pubmed 出版商

Wang L, Rajah A, Brown C, McCaffrey L. CD13 orients the apical-basal polarity axis necessary for lumen formation. Nat Commun. 2021;12:4697 pubmed 出版商

Watson A, Grant A, Parker S, Hill S, Whalen M, Chakrabarti J, et al. Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning. Cell Rep. 2021;35:109293 pubmed 出版商

Ramos Morales E, Bayam E, Del Pozo Rodríguez J, Salinas Giegé T, Marek M, Tilly P, et al. The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination. Nucleic Acids Res. 2021;49:6529-6548 pubmed 出版商

Kildey K, Gandhi N, Sahin K, Shah E, Boittier E, Duijf P, et al. Elevating CDCA3 levels in non-small cell lung cancer enhances sensitivity to platinum-based chemotherapy. Commun Biol. 2021;4:638 pubmed 出版商

Nakajima W, Miyazaki K, Asano Y, Kubota S, Tanaka N. Krüppel-Like Factor 4 and Its Activator APTO-253 Induce NOXA-Mediated, p53-Independent Apoptosis in Triple-Negative Breast Cancer Cells. Genes (Basel). 2021;12: pubmed 出版商

Kariya Y, Oyama M, Suzuki T, Kariya Y. αvβ3 Integrin induces partial EMT independent of TGF-β signaling. Commun Biol. 2021;4:490 pubmed 出版商

Goldfarb A, Freeman K, Sahu R, Elagib K, Holy M, Arneja A, et al. Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia. Nat Commun. 2021;12:1645 pubmed 出版商

Li T, Huang T, Du M, Chen X, Du F, Ren J, et al. Phosphorylation and chromatin tethering prevent cGAS activation during mitosis. Science. 2021;371: pubmed 出版商

Vergarajauregui S, Becker R, Steffen U, Sharkova M, Esser T, Petzold J, et al. AKAP6 orchestrates the nuclear envelope microtubule-organizing center by linking golgi and nucleus via AKAP9. elife. 2020;9: pubmed 出版商

Fomicheva M, Macara I. Genome-wide CRISPR screen identifies noncanonical NF-κB signaling as a regulator of density-dependent proliferation. elife. 2020;9: pubmed 出版商

Yan J, Bengtson C, Buchthal B, Hagenston A, Bading H. Coupling of NMDA receptors and TRPM4 guides discovery of unconventional neuroprotectants. Science. 2020;370: pubmed 出版商

Rogerson C, Ogden S, Britton E, Ang Y, Sharrocks A. Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to oesophageal adenocarcinoma. elife. 2020;9: pubmed 出版商

Varela Eirin M, Carpintero Fernández P, Sánchez Temprano A, Varela Vazquez A, Paíno C, Casado Diaz A, et al. Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis. Aging (Albany NY). 2020;12:15882-15905 pubmed 出版商

Berges R, Tchoghandjian A, Serge A, Honore S, Figarella Branger D, Bachmann F, et al. EB1-dependent long survival of glioblastoma-grafted mice with the oral tubulin-binder BAL101553 is associated with inhibition of tumor angiogenesis. Oncotarget. 2020;11:759-774 pubmed 出版商

Nagaoka S, Nakaki F, Miyauchi H, Nosaka Y, Ohta H, Yabuta Y, et al. ZGLP1 is a determinant for the oogenic fate in mice. Science. 2020;: pubmed 出版商

Bodrug T, Wilson Kubalek E, Nithianantham S, Thompson A, Alfieri A, Gaska I, et al. The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding. elife. 2020;9: pubmed 出版商

Lehmann M, Lukonin I, Noe F, Schmoranzer J, Clementi C, Loerke D, et al. Nanoscale coupling of endocytic pit growth and stability. Sci Adv. 2019;5:eaax5775 pubmed 出版商

Larson G, Tran V, Yu S, Cai Y, Higgins C, Smith D, et al. EPS8 Facilitates Uncoating of Influenza A Virus. Cell Rep. 2019;29:2175-2183.e4 pubmed 出版商

Vohnoutka R, Gulvady A, Goreczny G, Alpha K, Handelman S, Sexton J, et al. The focal adhesion scaffold protein Hic-5 regulates vimentin organization in fibroblasts. Mol Biol Cell. 2019;30:3037-3056 pubmed 出版商

Morris J, Yashinskie J, Koche R, Chandwani R, Tian S, Chen C, et al. α-Ketoglutarate links p53 to cell fate during tumour suppression. Nature. 2019;573:595-599 pubmed 出版商

Morishita H, Zhao Y, Tamura N, Nishimura T, Kanda Y, Sakamaki Y, et al. A critical role of VMP1 in lipoprotein secretion. elife. 2019;8: pubmed 出版商

Barbero G, Castro M, Villanueva M, Quezada M, Fernández N, Demorrow S, et al. An Autocrine Wnt5a Loop Promotes NF-κB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma. Cells. 2019;8: pubmed 出版商

Wang R, Yu R, Zhu C, Lin H, Lu X, Wang H. Tubulin detyrosination promotes human trophoblast syncytium formation. J Mol Cell Biol. 2019;: pubmed 出版商

Hartono -, Hazawa M, Lim K, Dewi F, Kobayashi A, Wong R. Nucleoporin Nup58 localizes to centrosomes and mid-bodies during mitosis. Cell Div. 2019;14:7 pubmed 出版商

Dorsch L, Schuldt M, dos Remedios C, Schinkel A, de Jong P, Michels M, et al. Protein Quality Control Activation and Microtubule Remodeling in Hypertrophic Cardiomyopathy. Cells. 2019;8: pubmed 出版商

Marcus J, Bejerano Sagie M, Patterson N, Bagchi S, Verkhusha V, Connolly D, et al. Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions. Oncogene. 2019;38:5839-5859 pubmed 出版商

Sajini A, Choudhury N, Wagner R, Bornelöv S, Selmi T, Spanos C, et al. Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation. Nat Commun. 2019;10:2550 pubmed 出版商

Sonego M, Pellarin I, Costa A, Vinciguerra G, Coan M, Kraut A, et al. USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability. Sci Adv. 2019;5:eaav3235 pubmed 出版商

A M, Fung T, Kettenbach A, Chakrabarti R, Higgs H. A complex containing lysine-acetylated actin inhibits the formin INF2. Nat Cell Biol. 2019;21:592-602 pubmed 出版商

Pluvinage J, Haney M, Smith B, Sun J, Iram T, Bonanno L, et al. CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. Nature. 2019;568:187-192 pubmed 出版商

Tsai C, Tsai C, Yi J, Kao H, Huang Y, Wang C, et al. Activin A regulates the epidermal growth factor receptor promoter by activating the PI3K/SP1 pathway in oral squamous cell carcinoma cells. Sci Rep. 2019;9:5197 pubmed 出版商

Patel N, Wang J, Shiozawa K, Jones K, Zhang Y, Prokop J, et al. HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression. iScience. 2019;13:43-54 pubmed 出版商

Smith B, Wang S, Jaime Figueroa S, Harbin A, Wang J, Hamman B, et al. Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase. Nat Commun. 2019;10:131 pubmed 出版商

Weinberg S, Singer B, Steinert E, Martinez C, Mehta M, Martínez Reyes I, et al. Mitochondrial complex III is essential for suppressive function of regulatory T cells. Nature. 2019;565:495-499 pubmed 出版商

Cui Y, Carosi J, Yang Z, Ariotti N, Kerr M, Parton R, et al. Retromer has a selective function in cargo sorting via endosome transport carriers. J Cell Biol. 2019;218:615-631 pubmed 出版商

Makhoul C, Gosavi P, Duffield R, Delbridge B, Williamson N, Gleeson P. Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture. Mol Biol Cell. 2019;30:370-386 pubmed 出版商

Arii J, Watanabe M, Maeda F, Tokai Nishizumi N, Chihara T, Miura M, et al. ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity. Nat Commun. 2018;9:3379 pubmed 出版商

Zhang J, Wu T, Simon J, Takada M, Saito R, Fan C, et al. VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma. Science. 2018;361:290-295 pubmed 出版商

Song P, Perkins B. Developmental expression of the zebrafish Arf-like small GTPase paralogs arl13a and arl13b. Gene Expr Patterns. 2018;29:82-87 pubmed 出版商

Peltzer N, Darding M, Montinaro A, Dráber P, Draberova H, Kupka S, et al. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. Nature. 2018;557:112-117 pubmed 出版商

Muhar M, Ebert A, Neumann T, Umkehrer C, Jude J, Wieshofer C, et al. SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis. Science. 2018;360:800-805 pubmed 出版商

Qin L, Ma K, Wang Z, Hu Z, Matas E, Wei J, et al. Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. Nat Neurosci. 2018;21:564-575 pubmed 出版商

Ruppert J, Samejima K, Platani M, Molina O, Kimura H, Jeyaprakash A, et al. HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry. EMBO J. 2018;37: pubmed 出版商

Matson J, Dumitru R, Coryell P, Baxley R, Chen W, Twaroski K, et al. Rapid DNA replication origin licensing protects stem cell pluripotency. elife. 2017;6: pubmed 出版商

Qu X, Yuan F, Corona C, Pasini S, Pero M, Gundersen G, et al. Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ1-42 synaptotoxicity. J Cell Biol. 2017;216:3161-3178 pubmed 出版商

Magescas J, Sengmanivong L, Viau A, Mayeux A, Dang T, Burtin M, et al. Spindle pole cohesion requires glycosylation-mediated localization of NuMA. Sci Rep. 2017;7:1474 pubmed 出版商

Allison R, Edgar J, Pearson G, Rizo T, Newton T, Günther S, et al. Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia. J Cell Biol. 2017;216:1337-1355 pubmed 出版商

Filipescu D, Naughtin M, Podsypanina K, Lejour V, Wilson L, Gurard Levin Z, et al. Essential role for centromeric factors following p53 loss and oncogenic transformation. Genes Dev. 2017;31:463-480 pubmed 出版商

Bohnacker T, Prota A, Beaufils F, Burke J, Melone A, Inglis A, et al. Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention. Nat Commun. 2017;8:14683 pubmed 出版商

Martínez Martín N, Maldonado P, Gasparrini F, Frederico B, Aggarwal S, Gaya M, et al. A switch from canonical to noncanonical autophagy shapes B cell responses. Science. 2017;355:641-647 pubmed 出版商

Francis J, Newman L, Cunningham L, Kahn R. A Trimer Consisting of the Tubulin-specific Chaperone D (TBCD), Regulatory GTPase ARL2, and β-Tubulin Is Required for Maintaining the Microtubule Network. J Biol Chem. 2017;292:4336-4349 pubmed 出版商

Inoue D, Stemmer M, Thumberger T, Ruppert T, Bärenz F, Wittbrodt J, et al. Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses. Nat Commun. 2017;8:14090 pubmed 出版商

Bendre S, Rondelet A, Hall C, Schmidt N, Lin Y, Brouhard G, et al. GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK. J Cell Biol. 2016;215:631-647 pubmed

Qu Y, Hahn I, Webb S, Pearce S, Prokop A. Periodic actin structures in neuronal axons are required to maintain microtubules. Mol Biol Cell. 2017;28:296-308 pubmed 出版商

Capalbo L, Mela I, Abad M, Jeyaprakash A, Edwardson J, D Avino P. Coordinated regulation of the ESCRT-III component CHMP4C by the chromosomal passenger complex and centralspindlin during cytokinesis. Open Biol. 2016;6: pubmed

Nowacka J, Baumgartner C, Pelorosso C, Roth M, Zuber J, Baccarini M. MEK1 is required for the development of NRAS-driven leukemia. Oncotarget. 2016;7:80113-80130 pubmed 出版商

Andriani G, Almeida V, Faggioli F, Mauro M, Tsai W, Santambrogio L, et al. Whole Chromosome Instability induces senescence and promotes SASP. Sci Rep. 2016;6:35218 pubmed 出版商

Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed

Koch K, Hartmann R, Schröter F, Suwala A, Maciaczyk D, Krüger A, et al. Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells. Oncotarget. 2016;7:73414-73431 pubmed 出版商

Truong D, Puleo J, Llave A, Mouneimne G, Kamm R, Nikkhah M. Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment. Sci Rep. 2016;6:34094 pubmed 出版商

Frolikova M, Sebkova N, Ded L, Dvorakova Hortova K. Characterization of CD46 and ?1 integrin dynamics during sperm acrosome reaction. Sci Rep. 2016;6:33714 pubmed 出版商

Kotoku T, Kosaka K, Nishio M, Ishida Y, Kawaichi M, Matsuda E. CIBZ Regulates Mesodermal and Cardiac Differentiation of by Suppressing T and Mesp1 Expression in Mouse Embryonic Stem Cells. Sci Rep. 2016;6:34188 pubmed 出版商

Chung I, Reichelt M, Shao L, Akita R, Koeppen H, Rangell L, et al. High cell-surface density of HER2 deforms cell membranes. Nat Commun. 2016;7:12742 pubmed 出版商

Hong X, Liu W, Song R, Shah J, Feng X, Tsang C, et al. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res. 2016;44:8855-8869 pubmed

Padhan N, Nordling T, Sundstrom M, Akerud P, Birgisson H, Nygren P, et al. High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer. BMC Cancer. 2016;16:683 pubmed 出版商

Meghini F, Martins T, Tait X, Fujimitsu K, Yamano H, Glover D, et al. Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit. Nat Commun. 2016;7:12607 pubmed 出版商

Perez C, Pérez Zúñiga F, Garrido F, Reytor E, Portillo F, Pajares M. The Oncogene PDRG1 Is an Interaction Target of Methionine Adenosyltransferases. PLoS ONE. 2016;11:e0161672 pubmed 出版商

Fokkelman M, BalcıoÄŸlu H, Klip J, Yan K, Verbeek F, Danen E, et al. Cellular adhesome screen identifies critical modulators of focal adhesion dynamics, cellular traction forces and cell migration behaviour. Sci Rep. 2016;6:31707 pubmed 出版商

Saatcioglu H, Cuevas I, Castrillon D. Control of Oocyte Reawakening by Kit. PLoS Genet. 2016;12:e1006215 pubmed 出版商

Furukawa Y, Tanemura K, Igarashi K, Ideta Otsuka M, Aisaki K, Kitajima S, et al. Learning and Memory Deficits in Male Adult Mice Treated with a Benzodiazepine Sleep-Inducing Drug during the Juvenile Period. Front Neurosci. 2016;10:339 pubmed 出版商

Liang J, Cao R, Zhang Y, Xia Y, Zheng Y, Li X, et al. PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis. Nat Commun. 2016;7:12431 pubmed 出版商

Dhamad A, Zhou Z, Zhou J, Du Y. Systematic Proteomic Identification of the Heat Shock Proteins (Hsp) that Interact with Estrogen Receptor Alpha (ER?) and Biochemical Characterization of the ER?-Hsp70 Interaction. PLoS ONE. 2016;11:e0160312 pubmed 出版商

Fritsch K, Mernberger M, Nist A, Stiewe T, Brehm A, Jacob R. Galectin-3 interacts with components of the nuclear ribonucleoprotein complex. BMC Cancer. 2016;16:502 pubmed 出版商

Meitinger F, Anzola J, Kaulich M, Richardson A, Stender J, Benner C, et al. 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J Cell Biol. 2016;214:155-66 pubmed 出版商

Belvedere R, Bizzarro V, Forte G, Dal Piaz F, Parente L, Petrella A. Annexin A1 contributes to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of Formyl Peptide Receptor pathway. Sci Rep. 2016;6:29660 pubmed 出版商

Miles D, de Vries N, Gisler S, Lieftink C, Akhtar W, Gogola E, et al. TRIM28 is an Epigenetic Barrier to Induced Pluripotent Stem Cell Reprogramming. Stem Cells. 2017;35:147-157 pubmed 出版商

Yang D, Yuan Q, Balakrishnan A, Bantel H, Klusmann J, Manns M, et al. MicroRNA-125b-5p mimic inhibits acute liver failure. Nat Commun. 2016;7:11916 pubmed 出版商

Bennesch M, Segala G, Wider D, Picard D. LSD1 engages a corepressor complex for the activation of the estrogen receptor ? by estrogen and cAMP. Nucleic Acids Res. 2016;44:8655-8670 pubmed

Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed 出版商

Eymery A, Liu Z, Ozonov E, Stadler M, Peters A. The methyltransferase Setdb1 is essential for meiosis and mitosis in mouse oocytes and early embryos. Development. 2016;143:2767-79 pubmed 出版商

Yin Y, Gao D, Wang Y, Wang Z, Wang X, Ye J, et al. Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling. Proc Natl Acad Sci U S A. 2016;113:E3773-81 pubmed 出版商

Matsumura S, Kojidani T, Kamioka Y, Uchida S, Haraguchi T, Kimura A, et al. Interphase adhesion geometry is transmitted to an internal regulator for spindle orientation via caveolin-1. Nat Commun. 2016;7:ncomms11858 pubmed 出版商

Bergstralh D, Lovegrove H, Kujawiak I, Dawney N, Zhu J, Cooper S, et al. Pins is not required for spindle orientation in the Drosophila wing disc. Development. 2016;143:2573-81 pubmed 出版商

Yin Y, Wang Y, Gao D, Ye J, Wang X, Fang L, et al. Accumulation of human full-length tau induces degradation of nicotinic acetylcholine receptor α4 via activating calpain-2. Sci Rep. 2016;6:27283 pubmed 出版商

van Ree J, Nam H, Jeganathan K, Kanakkanthara A, van Deursen J. Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes. Nat Cell Biol. 2016;18:814-21 pubmed 出版商

Daubon T, Spuul P, Alonso F, Fremaux I, Genot E. VEGF-A stimulates podosome-mediated collagen-IV proteolysis in microvascular endothelial cells. J Cell Sci. 2016;129:2586-98 pubmed 出版商

Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka I. A dual molecular analogue tuner for dissecting protein function in mammalian cells. Nat Commun. 2016;7:11742 pubmed 出版商

Kobayashi E, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, et al. Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription. Nat Commun. 2016;7:11624 pubmed 出版商

Umezu K, Hiradate Y, Oikawa T, Ishiguro H, Numabe T, Hara K, et al. Exogenous neurotensin modulates sperm function in Japanese Black cattle. J Reprod Dev. 2016;62:409-14 pubmed 出版商

Kessler S, Laggai S, Van Wonterg E, Gemperlein K, Muller R, Haybaeck J, et al. Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation. Front Physiol. 2016;7:147 pubmed 出版商

Guinot A, Oeztuerk Winder F, Ventura J. miR-17-92/p38? Dysregulation Enhances Wnt Signaling and Selects Lgr6+ Cancer Stem-like Cells during Lung Adenocarcinoma Progression. Cancer Res. 2016;76:4012-22 pubmed 出版商

de Jong P, Taniguchi K, Harris A, Bertin S, Takahashi N, Duong J, et al. ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun. 2016;7:11551 pubmed 出版商

Chang C, Hsu W, Tsai J, Tang C, Tang T. CEP295 interacts with microtubules and is required for centriole elongation. J Cell Sci. 2016;129:2501-13 pubmed 出版商

Rao S, Flores Rodriguez N, Page S, Wong C, Robinson P, Chircop M. The Clathrin-dependent Spindle Proteome. Mol Cell Proteomics. 2016;15:2537-53 pubmed 出版商

Takenaka N, Nihata Y, Satoh T. Rac1 Activation Caused by Membrane Translocation of a Guanine Nucleotide Exchange Factor in Akt2-Mediated Insulin Signaling in Mouse Skeletal Muscle. PLoS ONE. 2016;11:e0155292 pubmed 出版商

Marei H, Carpy A, Macek B, Malliri A. Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors. Cell Cycle. 2016;15:1961-74 pubmed 出版商

Riaz M, Raz Y, van Putten M, Paniagua Soriano G, Krom Y, Florea B, et al. PABPN1-Dependent mRNA Processing Induces Muscle Wasting. PLoS Genet. 2016;12:e1006031 pubmed 出版商

Marthandan S, Baumgart M, Priebe S, Groth M, Schaer J, Kaether C, et al. Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq. PLoS ONE. 2016;11:e0154531 pubmed 出版商

Rapiteanu R, Davis L, Williamson J, Timms R, Paul Luzio J, Lehner P. A Genetic Screen Identifies a Critical Role for the WDR81-WDR91 Complex in the Trafficking and Degradation of Tetherin. Traffic. 2016;17:940-58 pubmed 出版商

Strappazzon F, Di Rita A, Cianfanelli V, D Orazio M, Nazio F, Fimia G, et al. Prosurvival AMBRA1 turns into a proapoptotic BH3-like protein during mitochondrial apoptosis. Autophagy. 2016;12:963-75 pubmed 出版商

Lee K, Lee H, Lin H, Tsay H, Tsai F, Shyue S, et al. Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease. J Neuroinflammation. 2016;13:92 pubmed 出版商

Mata Garrido J, Casafont I, Tapia O, Berciano M, Lafarga M. Neuronal accumulation of unrepaired DNA in a novel specific chromatin domain: structural, molecular and transcriptional characterization. Acta Neuropathol Commun. 2016;4:41 pubmed 出版商

Kwenda L, Collins C, Dattoli A, Dunleavy E. Nucleolar activity and CENP-C regulate CENP-A and CAL1 availability for centromere assembly in meiosis. Development. 2016;143:1400-12 pubmed 出版商

Brüggen B, Kremser C, Bickert A, Ebel P, Vom Dorp K, Schultz K, et al. Defective ceramide synthases in mice cause reduced amplitudes in electroretinograms and altered sphingolipid composition in retina and cornea. Eur J Neurosci. 2016;44:1700-13 pubmed 出版商

Waisbourd Zinman O, Koh H, Tsai S, Lavrut P, Dang C, Zhao X, et al. The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17. Hepatology. 2016;64:880-93 pubmed 出版商

Chiang T, le Sage C, Larrieu D, Demir M, Jackson S. CRISPR-Cas9(D10A) nickase-based genotypic and phenotypic screening to enhance genome editing. Sci Rep. 2016;6:24356 pubmed 出版商

Taguchi K, Takaku M, Egner P, Morita M, Kaneko T, Mashimo T, et al. Generation of a New Model Rat: Nrf2 Knockout Rats Are Sensitive to Aflatoxin B1 Toxicity. Toxicol Sci. 2016;152:40-52 pubmed 出版商

Juárez Vicente F, Luna Pelaez N, Garcia Dominguez M. The Sumo protease Senp7 is required for proper neuronal differentiation. Biochim Biophys Acta. 2016;1863:1490-8 pubmed 出版商

Strickland S, Vande Pol S. The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC. J Virol. 2016;90:5611-5621 pubmed 出版商

McKenzie C, Bassi Z, Debski J, Gottardo M, Callaini G, Dadlez M, et al. Cross-regulation between Aurora B and Citron kinase controls midbody architecture in cytokinesis. Open Biol. 2016;6: pubmed 出版商

Zhao W, Liu J, Zhang X, Deng L. MLL5 maintains spindle bipolarity by preventing aberrant cytosolic aggregation of PLK1. J Cell Biol. 2016;212:829-43 pubmed 出版商

Chavali P, Chandrasekaran G, Barr A, Tátrai P, Taylor C, Papachristou E, et al. A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer. Nat Commun. 2016;7:11005 pubmed 出版商

Mitxelena J, Apraiz A, Vallejo Rodríguez J, Malumbres M, Zubiaga A. E2F7 regulates transcription and maturation of multiple microRNAs to restrain cell proliferation. Nucleic Acids Res. 2016;: pubmed

Makani V, Jang Y, Christopher K, Judy W, Eckstein J, Hensley K, et al. BBB-Permeable, Neuroprotective, and Neurotrophic Polysaccharide, Midi-GAGR. PLoS ONE. 2016;11:e0149715 pubmed 出版商

Nakayama R, Zhang Y, Czaplinski J, Anatone A, Sicinska E, Fletcher J, et al. Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma. Oncotarget. 2016;7:16581-92 pubmed 出版商

McLaughlin D, Coey C, Yang W, Drohat A, Matunis M. Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo. J Biol Chem. 2016;291:9014-24 pubmed 出版商

Xu Q, Zhang Y, Wei Q, Huang Y, Hu J, Ling K. Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis. Nat Commun. 2016;7:10777 pubmed 出版商

Jia L, Li B, Yu H. The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation. Nat Commun. 2016;7:10818 pubmed 出版商

Jackson S, Olufs Z, Tran K, Zaidan N, Sridharan R. Alternative Routes to Induced Pluripotent Stem Cells Revealed by Reprogramming of the Neural Lineage. Stem Cell Reports. 2016;6:302-11 pubmed 出版商

del Río C, Navarrete C, Collado J, Bellido M, Gómez Cañas M, Pazos M, et al. The cannabinoid quinol VCE-004.8 alleviates bleomycin-induced scleroderma and exerts potent antifibrotic effects through peroxisome proliferator-activated receptor-γ and CB2 pathways. Sci Rep. 2016;6:21703 pubmed 出版商

Baron A, von Schubert C, Cubizolles F, Siemeister G, Hitchcock M, Mengel A, et al. Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524. elife. 2016;5: pubmed 出版商

Malecova B, Dall Agnese A, Madaro L, Gatto S, Coutinho Toto P, Albini S, et al. TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells. elife. 2016;5: pubmed 出版商

Liu A, Zhou Z, Dang R, Zhu Y, Qi J, He G, et al. Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization. J Cell Biol. 2016;212:449-63 pubmed 出版商

Wike C, Graves H, Hawkins R, Gibson M, Ferdinand M, Zhang T, et al. Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis. elife. 2016;5:e11402 pubmed 出版商

Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed 出版商

Sharma A, Lyashchenko A, Lu L, Nasrabady S, Elmaleh M, Mendelsohn M, et al. ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function. Nat Commun. 2016;7:10465 pubmed 出版商

Dos Santos E, Carneiro Lobo T, Aoki M, Levantini E, Bassères D. Aurora kinase targeting in lung cancer reduces KRAS-induced transformation. Mol Cancer. 2016;15:12 pubmed 出版商

Swaminathan V, Fischer R, Waterman C. The FAK-Arp2/3 interaction promotes leading edge advance and haptosensing by coupling nascent adhesions to lamellipodia actin. Mol Biol Cell. 2016;27:1085-100 pubmed 出版商

Franz A, Pirson P, Pilger D, Halder S, Achuthankutty D, Kashkar H, et al. Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression. Nat Commun. 2016;7:10612 pubmed 出版商

Stevenson J, Conaty E, Walsh R, Poidomani P, Samoriski C, Scollins B, et al. The Amyloid Precursor Protein of Alzheimer's Disease Clusters at the Organelle/Microtubule Interface on Organelles that Bind Microtubules in an ATP Dependent Manner. PLoS ONE. 2016;11:e0147808 pubmed 出版商

Button R, Vincent J, Strang C, Luo S. Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget. 2016;7:5157-75 pubmed 出版商

Rasmussen R, Gajjar M, Jensen K, Hamerlik P. Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma. Mol Oncol. 2016;10:751-63 pubmed 出版商

Luchsinger L, de Almeida M, Corrigan D, Mumau M, Snoeck H. Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential. Nature. 2016;529:528-31 pubmed 出版商

Kelkar M, Senthilkumar K, Jadhav S, Gupta S, Ahn B, De A. Enhancement of human sodium iodide symporter gene therapy for breast cancer by HDAC inhibitor mediated transcriptional modulation. Sci Rep. 2016;6:19341 pubmed 出版商

Mauvezin C, Neisch A, Ayala C, Kim J, Beltrame A, Braden C, et al. Coordination of autophagosome-lysosome fusion and transport by a Klp98A-Rab14 complex in Drosophila. J Cell Sci. 2016;129:971-82 pubmed 出版商

Hori A, Barnouin K, Snijders A, Toda T. A non-canonical function of Plk4 in centriolar satellite integrity and ciliogenesis through PCM1 phosphorylation. EMBO Rep. 2016;17:326-37 pubmed 出版商

Murakami K, Günesdogan U, Zylicz J, Tang W, Sengupta R, Kobayashi T, et al. NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers. Nature. 2016;529:403-407 pubmed 出版商

Zhou H, Wang T, Zheng T, Teng J, Chen J. Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2. Nat Commun. 2016;7:10151 pubmed 出版商

Kajtez J, Solomatina A, Novak M, Polak B, VukuÅ¡ić K, Rüdiger J, et al. Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores. Nat Commun. 2016;7:10298 pubmed 出版商

Nelson J, Cook E, Loregger A, Hoeksema M, Scheij S, Kovacevic I, et al. Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake. J Biol Chem. 2016;291:4813-25 pubmed 出版商

Ge C, Che L, Du C. The UBC Domain Is Required for BRUCE to Promote BRIT1/MCPH1 Function in DSB Signaling and Repair Post Formation of BRUCE-USP8-BRIT1 Complex. PLoS ONE. 2015;10:e0144957 pubmed 出版商

Stanic J, Carta M, Eberini I, Pelucchi S, Marcello E, Genazzani A, et al. Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex. Nat Commun. 2015;6:10181 pubmed 出版商

Giampietro C, Disanza A, Bravi L, Barrios Rodiles M, Corada M, Frittoli E, et al. The actin-binding protein EPS8 binds VE-cadherin and modulates YAP localization and signaling. J Cell Biol. 2015;211:1177-92 pubmed 出版商

Franco Villanueva A, Wandosell F, Antón I. Neuritic complexity of hippocampal neurons depends on WIP-mediated mTORC1 and Abl family kinases activities. Brain Behav. 2015;5:e00359 pubmed 出版商

Mills K, Brocardo M, Henderson B. APC binds the Miro/Milton motor complex to stimulate transport of mitochondria to the plasma membrane. Mol Biol Cell. 2016;27:466-82 pubmed 出版商

Müller Schiffmann A, Herring A, Abdel Hafiz L, Chepkova A, Schäble S, Wedel D, et al. Amyloid-β dimers in the absence of plaque pathology impair learning and synaptic plasticity. Brain. 2016;139:509-25 pubmed 出版商

Dupont T, Yang S, Patel J, Hatzi K, Malik A, Tam W, et al. Selective targeting of BCL6 induces oncogene addiction switching to BCL2 in B-cell lymphoma. Oncotarget. 2016;7:3520-32 pubmed 出版商

Ageta Ishihara N, Yamazaki M, Konno K, Nakayama H, Abe M, Hashimoto K, et al. A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance. Nat Commun. 2015;6:10090 pubmed 出版商

Ohashi A, Ohori M, Iwai K, Nambu T, Miyamoto M, Kawamoto T, et al. A Novel Time-Dependent CENP-E Inhibitor with Potent Antitumor Activity. PLoS ONE. 2015;10:e0144675 pubmed 出版商

Grandy R, Whitfield T, Wu H, Fitzgerald M, VanOudenhove J, Zaidi S, et al. Genome-Wide Studies Reveal that H3K4me3 Modification in Bivalent Genes Is Dynamically Regulated during the Pluripotent Cell Cycle and Stabilized upon Differentiation. Mol Cell Biol. 2016;36:615-27 pubmed 出版商

Garcia Manteiga J, Bonfiglio S, Folladori L, Malosio M, Lazarevic D, Stupka E, et al. REST-Governed Gene Expression Profiling in a Neuronal Cell Model Reveals Novel Direct and Indirect Processes of Repression and Up-Regulation. Front Cell Neurosci. 2015;9:438 pubmed 出版商

Cuttano R, Rudini N, Bravi L, Corada M, Giampietro C, Papa E, et al. KLF4 is a key determinant in the development and progression of cerebral cavernous malformations. EMBO Mol Med. 2016;8:6-24 pubmed 出版商

Ni Y, Tao L, Chen C, Song H, Li Z, Gao Y, et al. The Deubiquitinase USP17 Regulates the Stability and Nuclear Function of IL-33. Int J Mol Sci. 2015;16:27956-66 pubmed 出版商

Gao X, Krokowski D, Guan B, Bederman I, Majumder M, Parisien M, et al. Quantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the integrated stress response. elife. 2015;4:e10067 pubmed 出版商

dos Santos N, Matias A, Higa G, Kihara A, Cerchiaro G. Copper Uptake in Mammary Epithelial Cells Activates Cyclins and Triggers Antioxidant Response. Oxid Med Cell Longev. 2015;2015:162876 pubmed 出版商

Gogendeau D, Siudeja K, Gambarotto D, Pennetier C, Bardin A, Basto R. Aneuploidy causes premature differentiation of neural and intestinal stem cells. Nat Commun. 2015;6:8894 pubmed 出版商

Jahic A, Khundadze M, Jaenisch N, Schüle R, Klimpe S, Klebe S, et al. The spectrum of KIAA0196 variants, and characterization of a murine knockout: implications for the mutational mechanism in hereditary spastic paraplegia type SPG8. Orphanet J Rare Dis. 2015;10:147 pubmed 出版商

Iarriccio L, Manguán García C, Pintado Berninches L, Mancheño J, Molina A, Perona R, et al. GSE4, a Small Dyskerin- and GSE24.2-Related Peptide, Induces Telomerase Activity, Cell Proliferation and Reduces DNA Damage, Oxidative Stress and Cell Senescence in Dyskerin Mutant Cells. PLoS ONE. 2015;10:e0142980 pubmed 出版商

Furuta M, Hori T, Fukagawa T. Chromatin binding of RCC1 during mitosis is important for its nuclear localization in interphase. Mol Biol Cell. 2016;27:371-81 pubmed 出版商

Fontinha D, Lopes F, Marques S, Alenquer M, Simas J. Murid Gammaherpesvirus Latency-Associated Protein M2 Promotes the Formation of Conjugates between Transformed B Lymphoma Cells and T Helper Cells. PLoS ONE. 2015;10:e0142540 pubmed 出版商

Stanojlović M, GuÅ¡evac I, Grković I, Zlatković J, Mitrović N, Zarić M, et al. Effects of chronic cerebral hypoperfusion and low-dose progesterone treatment on apoptotic processes, expression and subcellular localization of key elements within Akt and Erk signaling pathways in rat hippocampus. Neuroscience. 2015;311:308-21 pubmed 出版商

Jia D, Tan Y, Liu H, Ooi S, Li L, Wright K, et al. Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo. Oncotarget. 2016;7:771-85 pubmed 出版商

Dumas A, Lê Bury G, Marie Anaïs F, Herit F, Mazzolini J, Guilbert T, et al. The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking. J Cell Biol. 2015;211:359-72 pubmed 出版商

Zampieri A, Champagne J, Auzemery B, Fuentes I, Maurel B, Bienvenu F. Hyper sensitive protein detection by Tandem-HTRF reveals Cyclin D1 dynamics in adult mouse. Sci Rep. 2015;5:15739 pubmed 出版商

Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, et al. Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat Immunol. 2015;16:1235-44 pubmed 出版商

Radford S, Hoang T, Głuszek A, Ohkura H, McKim K. Lateral and End-On Kinetochore Attachments Are Coordinated to Achieve Bi-orientation in Drosophila Oocytes. PLoS Genet. 2015;11:e1005605 pubmed 出版商

Yuzugullu H, Baitsch L, Von T, Steiner A, Tong H, Ni J, et al. A PI3K p110β-Rac signalling loop mediates Pten-loss-induced perturbation of haematopoiesis and leukaemogenesis. Nat Commun. 2015;6:8501 pubmed 出版商

Miles W, Lepesant J, Bourdeaux J, Texier M, Kerenyi M, Nakakido M, et al. The LSD1 Family of Histone Demethylases and the Pumilio Posttranscriptional Repressor Function in a Complex Regulatory Feedback Loop. Mol Cell Biol. 2015;35:4199-211 pubmed 出版商

Bagulho A, Vilas Boas F, Pena A, Peneda C, Santos F, Jerónimo A, et al. The extracellular matrix modulates H2O2 degradation and redox signaling in endothelial cells. Redox Biol. 2015;6:454-460 pubmed 出版商

Hasanagic M, van Meel E, Luan S, Aurora R, Kornfeld S, Eissenberg J. The lysosomal enzyme receptor protein (LERP) is not essential, but is implicated in lysosomal function in Drosophila melanogaster. Biol Open. 2015;4:1316-25 pubmed 出版商

Beck K, Ehmann N, Andlauer T, Ljaschenko D, Strecker K, Fischer M, et al. Loss of the Coffin-Lowry syndrome-associated gene RSK2 alters ERK activity, synaptic function and axonal transport in Drosophila motoneurons. Dis Model Mech. 2015;8:1389-400 pubmed 出版商

Nemazanyy I, Montagnac G, Russell R, Morzyglod L, Burnol A, Guan K, et al. Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling. Nat Commun. 2015;6:8283 pubmed 出版商

Zhu L, Wang Z, Wang W, Wang C, Hua S, Su Z, et al. Mitotic Protein CSPP1 Interacts with CENP-H Protein to Coordinate Accurate Chromosome Oscillation in Mitosis. J Biol Chem. 2015;290:27053-66 pubmed 出版商

Qiao Y, Lin S, Chen Y, Voon D, Zhu F, Chuang L, et al. RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer. Oncogene. 2016;35:2664-74 pubmed 出版商

Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, et al. The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. PLoS Genet. 2015;11:e1005503 pubmed 出版商

Hu M, Wang Z, Teng Y, Jiang Z, Ma X, Hou N, et al. Loss of protein phosphatase 6 in oocytes causes failure of meiosis II exit and impaired female fertility. J Cell Sci. 2015;128:3769-80 pubmed 出版商

Plescher M, Teleman A, Demetriades C. TSC2 mediates hyperosmotic stress-induced inactivation of mTORC1. Sci Rep. 2015;5:13828 pubmed 出版商

Marthandan S, Priebe S, Baumgart M, Groth M, Cellerino A, Guthke R, et al. Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts. Biomed Res Int. 2015;2015:731938 pubmed 出版商

Van de Mark D, Kong D, Loncarek J, Stearns T. MDM1 is a microtubule-binding protein that negatively regulates centriole duplication. Mol Biol Cell. 2015;26:3788-802 pubmed 出版商

Bida O, Gidoni M, Ideses D, Efroni S, Ginsberg D. A novel mitosis-associated lncRNA, MA-linc1, is required for cell cycle progression and sensitizes cancer cells to Paclitaxel. Oncotarget. 2015;6:27880-90 pubmed 出版商

Moreau K, Ghislat G, Hochfeld W, Renna M, Zavodszky E, Runwal G, et al. Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy. Nat Commun. 2015;6:8045 pubmed 出版商

Archibald A, Al Masri M, Liew Spilger A, McCaffrey L. Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling. Mol Biol Cell. 2015;26:3578-95 pubmed 出版商

Meraviglia V, Azzimato V, Colussi C, Florio M, Binda A, Panariti A, et al. Acetylation mediates Cx43 reduction caused by electrical stimulation. J Mol Cell Cardiol. 2015;87:54-64 pubmed 出版商

Guo Y, Zheng Y. Lamins position the nuclear pores and centrosomes by modulating dynein. Mol Biol Cell. 2015;26:3379-89 pubmed 出版商

Roncero A, López Nieva P, Cobos Fernández M, Villa Morales M, González Sánchez L, López Lorenzo J, et al. Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development. Leukemia. 2016;30:94-103 pubmed 出版商

Kortüm F, Harms F, Hennighausen N, Rosenberger G. αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor. PLoS ONE. 2015;10:e0132737 pubmed 出版商

Schraivogel D, Schindler S, Danner J, Kremmer E, Pfaff J, Hannus S, et al. Importin-β facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels. Nucleic Acids Res. 2015;43:7447-61 pubmed 出版商

Felzen V, Hiebel C, Koziollek Drechsler I, Reißig S, Wolfrum U, Kögel D, et al. Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis. 2015;6:e1812 pubmed 出版商

Ohashi A, Ohori M, Iwai K, Nakayama Y, Nambu T, Morishita D, et al. Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells. Nat Commun. 2015;6:7668 pubmed 出版商

Lin Y, Bhuwania R, Gromova K, Failla A, Lange T, Riecken K, et al. Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion. Oncotarget. 2015;6:18577-89 pubmed

Salinas Saavedra M, Stephenson T, Dunn C, Martindale M. Par system components are asymmetrically localized in ectodermal epithelia, but not during early development in the sea anemone Nematostella vectensis. Evodevo. 2015;6:20 pubmed 出版商

Whalley H, Porter A, Diamantopoulou Z, White G, Castañeda Saucedo E, Malliri A. Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation. Nat Commun. 2015;6:7437 pubmed 出版商

Kim D, Yeom J, Lee B, Lee K, Bae J, Rhee S. Inhibition of discoidin domain receptor 2-mediated lung cancer cells progression by gold nanoparticle-aptamer-assisted delivery of peptides containing transmembrane-juxtamembrane 1/2 domain. Biochem Biophys Res Commun. 2015;464:392-5 pubmed 出版商

Rato L, Alves M, Dias T, Cavaco J, Oliveira P. Testicular Metabolic Reprogramming in Neonatal Streptozotocin-Induced Type 2 Diabetic Rats Impairs Glycolytic Flux and Promotes Glycogen Synthesis. J Diabetes Res. 2015;2015:973142 pubmed 出版商

Selvaraj D, Gangadharan V, Michalski C, Kurejova M, Stösser S, Srivastava K, et al. A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain. Cancer Cell. 2015;27:780-96 pubmed 出版商

Luo W, Liu W, Hu X, Hanna M, Caravaca A, Paul S. Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody. Sci Rep. 2015;5:11161 pubmed 出版商

Dille S, Kleinschnitz E, Kontchou C, Nölke T, Häcker G. In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transport. Infect Immun. 2015;83:3268-80 pubmed 出版商

Krokowski D, Jobava R, Guan B, Farabaugh K, Wu J, Majumder M, et al. Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity. J Biol Chem. 2015;290:17822-37 pubmed 出版商

Barr A, Bakal C. A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. Sci Rep. 2015;5:10564 pubmed 出版商

Urban B, Collard T, Eagle C, Southern S, Greenhough A, Hamdollah Zadeh M, et al. BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling. Gut. 2016;65:1151-64 pubmed 出版商

Kim J, Kim B, Lee H, Thakkar S, Babbitt D, Eguchi S, et al. Shear stress-induced mitochondrial biogenesis decreases the release of microparticles from endothelial cells. Am J Physiol Heart Circ Physiol. 2015;309:H425-33 pubmed 出版商

Herms A, Bosch M, Reddy B, Schieber N, Fajardo A, Rupérez C, et al. AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation. Nat Commun. 2015;6:7176 pubmed 出版商

Alonso Curbelo D, Osterloh L, Cañón E, Calvo T, Martínez Herranz R, Karras P, et al. RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development. Oncotarget. 2015;6:11848-62 pubmed

Panic M, Hata S, Neuner A, Schiebel E. The centrosomal linker and microtubules provide dual levels of spatial coordination of centrosomes. PLoS Genet. 2015;11:e1005243 pubmed 出版商

Reales E, Bernabé Rubio M, Casares Arias J, Rentero C, Fernández Barrera J, Rangel L, et al. The MAL protein is crucial for proper membrane condensation at the ciliary base, which is required for primary cilium elongation. J Cell Sci. 2015;128:2261-70 pubmed 出版商

Tanas M, Ma S, Jadaan F, Ng C, Weigelt B, Reis Filho J, et al. Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein. Oncogene. 2016;35:929-38 pubmed 出版商

Moldovan J, Moran J. The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition. PLoS Genet. 2015;11:e1005121 pubmed 出版商

Breznau E, Semack A, Higashi T, Miller A. MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell-cell junctions in epithelial cells. Mol Biol Cell. 2015;26:2439-55 pubmed 出版商

Thress K, Paweletz C, Felip E, Cho B, Stetson D, Dougherty B, et al. Acquired EGFR C797S mutation mediates resistance to AZD9291 in non-small cell lung cancer harboring EGFR T790M. Nat Med. 2015;21:560-2 pubmed 出版商

Williamson R, Cowell C, Reville T, Roper J, Rendall T, Bass M. Coronin-1C Protein and Caveolin Protein Provide Constitutive and Inducible Mechanisms of Rac1 Protein Trafficking. J Biol Chem. 2015;290:15437-49 pubmed 出版商

Sato S, Kawamata Y, Takahashi A, Imai Y, Hanyu A, Okuma A, et al. Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice. Nat Commun. 2015;6:7035 pubmed 出版商

Carrigan I, Croll R, Wyeth R. Morphology, innervation, and peripheral sensory cells of the siphon of aplysia californica. J Comp Neurol. 2015;523:2409-25 pubmed 出版商

Vicuña L, Strochlic D, Latremoliere A, Bali K, Simonetti M, Husainie D, et al. The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase. Nat Med. 2015;21:518-23 pubmed 出版商

Gago Fuentes R, Fernández Puente P, Megias D, Carpintero Fernández P, Mateos J, Acea B, et al. Proteomic Analysis of Connexin 43 Reveals Novel Interactors Related to Osteoarthritis. Mol Cell Proteomics. 2015;14:1831-45 pubmed 出版商

Ceballos Chávez M, Subtil Rodríguez A, Giannopoulou E, Soronellas D, Vázquez Chávez E, Vicent G, et al. The chromatin Remodeler CHD8 is required for activation of progesterone receptor-dependent enhancers. PLoS Genet. 2015;11:e1005174 pubmed 出版商

Koizume S, Ito S, Nakamura Y, Yoshihara M, Furuya M, Yamada R, et al. Lipid starvation and hypoxia synergistically activate ICAM1 and multiple genes in an Sp1-dependent manner to promote the growth of ovarian cancer. Mol Cancer. 2015;14:77 pubmed 出版商

Tebbi A, Guittet O, Tuphile K, Cabrié A, Lepoivre M. Caspase-dependent Proteolysis of Human Ribonucleotide Reductase Small Subunits R2 and p53R2 during Apoptosis. J Biol Chem. 2015;290:14077-90 pubmed 出版商

Hori A, Peddie C, Collinson L, Toda T. Centriolar satellite- and hMsd1/SSX2IP-dependent microtubule anchoring is critical for centriole assembly. Mol Biol Cell. 2015;26:2005-19 pubmed 出版商

Chen A, Akhshi T, Lavoie B, Wilde A. Importin β2 Mediates the Spatio-temporal Regulation of Anillin through a Noncanonical Nuclear Localization Signal. J Biol Chem. 2015;290:13500-9 pubmed 出版商

Tabariès S, Annis M, Hsu B, Tam C, Savage P, Park M, et al. Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis. Oncotarget. 2015;6:9476-87 pubmed

Dorgau B, Herrling R, Schultz K, Greb H, Segelken J, Ströh S, et al. Connexin50 couples axon terminals of mouse horizontal cells by homotypic gap junctions. J Comp Neurol. 2015;523:2062-81 pubmed 出版商

Li L, Xu Z, Liu G, Xu C, Wang Z, Li X, et al. Expression of 1N3R-Tau isoform inhibits cell proliferation by inducing S phase arrest in N2a cells. PLoS ONE. 2015;10:e0119865 pubmed 出版商

Shin C, Grossmann A, Holmen S, Robinson J. The BRAF kinase domain promotes the development of gliomas in vivo. Genes Cancer. 2015;6:9-18 pubmed

Ainsua Enrich E, Serrano Candelas E, Álvarez Errico D, Picado C, Sayós J, Rivera J, et al. The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival. J Immunol. 2015;194:4309-18 pubmed 出版商

Takada S, Collins E, Kurahashi K. The FHA domain determines Drosophila Chk2/Mnk localization to key mitotic structures and is essential for early embryonic DNA damage responses. Mol Biol Cell. 2015;26:1811-28 pubmed 出版商

Coon B, Baeyens N, Han J, Budatha M, Ross T, Fang J, et al. Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex. J Cell Biol. 2015;208:975-86 pubmed 出版商

Kobayashi A, Hashizume C, Dowaki T, Wong R. Therapeutic potential of mitotic interaction between the nucleoporin Tpr and aurora kinase A. Cell Cycle. 2015;14:1447-58 pubmed 出版商

Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, et al. Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFα-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. PLoS ONE. 2015;10:e0119415 pubmed 出版商

Tassinari V, Campolo F, Cesarini V, Todaro F, Dolci S, Rossi P. Fgf9 inhibition of meiotic differentiation in spermatogonia is mediated by Erk-dependent activation of Nodal-Smad2/3 signaling and is antagonized by Kit Ligand. Cell Death Dis. 2015;6:e1688 pubmed 出版商

Cheng H, Chern Y, Chen I, Liu C, Li S, Chun S, et al. Effects on murine behavior and lifespan of selectively decreasing expression of mutant huntingtin allele by supt4h knockdown. PLoS Genet. 2015;11:e1005043 pubmed 出版商

Wengrod J, Wang D, Weiss S, Zhong H, Osman I, Gardner L. Phosphorylation of eIF2α triggered by mTORC1 inhibition and PP6C activation is required for autophagy and is aberrant in PP6C-mutated melanoma. Sci Signal. 2015;8:ra27 pubmed 出版商

Gillespie M, Gold E, Ramsey S, Podolsky I, Aderem A, Ranish J. An LXR-NCOA5 gene regulatory complex directs inflammatory crosstalk-dependent repression of macrophage cholesterol efflux. EMBO J. 2015;34:1244-58 pubmed 出版商

Tsuru A, Setoguchi T, Matsunoshita Y, Nagao Kitamoto H, Nagano S, Yokouchi M, et al. Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression. Br J Cancer. 2015;112:1232-40 pubmed 出版商

Xie Q, Wu Q, Horbinski C, Flavahan W, Yang K, Zhou W, et al. Mitochondrial control by DRP1 in brain tumor initiating cells. Nat Neurosci. 2015;18:501-10 pubmed 出版商

Carvallo L, Lopez L, Che F, Lim J, Eugenin E, Williams D, et al. Buprenorphine decreases the CCL2-mediated chemotactic response of monocytes. J Immunol. 2015;194:3246-58 pubmed 出版商

Banks C, Boanca G, Lee Z, Florens L, Washburn M. Proteins interacting with cloning scars: a source of false positive protein-protein interactions. Sci Rep. 2015;5:8530 pubmed 出版商

Beaven R, Dzhindzhev N, Qu Y, Hahn I, Dajas Bailador F, Ohkura H, et al. Drosophila CLIP-190 and mammalian CLIP-170 display reduced microtubule plus end association in the nervous system. Mol Biol Cell. 2015;26:1491-508 pubmed 出版商

Ito T, Taniguchi H, Fukagai K, Okamuro S, Kobayashi A. Inhibitory mechanism of FAT4 gene expression in response to actin dynamics during Src-induced carcinogenesis. PLoS ONE. 2015;10:e0118336 pubmed 出版商

Morris E, Assi K, Salh B, Dedhar S. Integrin-linked kinase links dynactin-1/dynactin-2 with cortical integrin receptors to orient the mitotic spindle relative to the substratum. Sci Rep. 2015;5:8389 pubmed 出版商

Kondapalli K, Llongueras J, Capilla González V, Prasad H, Hack A, Smith C, et al. A leak pathway for luminal protons in endosomes drives oncogenic signalling in glioblastoma. Nat Commun. 2015;6:6289 pubmed 出版商

Chen J, Ren J, Jing Q, Lu S, Zhang Y, Liu Y, et al. TSH/TSHR Signaling Suppresses Fatty Acid Synthase (FASN) Expression in Adipocytes. J Cell Physiol. 2015;230:2233-9 pubmed 出版商

Okumura M, Sakuma C, Miura M, Chihara T. Linking cell surface receptors to microtubules: tubulin folding cofactor D mediates Dscam functions during neuronal morphogenesis. J Neurosci. 2015;35:1979-90 pubmed 出版商

Horstick E, Jordan D, Bergeron S, Tabor K, Serpe M, Feldman B, et al. Increased functional protein expression using nucleotide sequence features enriched in highly expressed genes in zebrafish. Nucleic Acids Res. 2015;43:e48 pubmed 出版商

Santhana Kumar K, Tripolitsioti D, Ma M, Grählert J, Egli K, Fiaschetti G, et al. The Ser/Thr kinase MAP4K4 drives c-Met-induced motility and invasiveness in a cell-based model of SHH medulloblastoma. Springerplus. 2015;4:19 pubmed 出版商

Marsolier J, Perichon M, Debarry J, Villoutreix B, Chluba J, Lopez T, et al. Theileria parasites secrete a prolyl isomerase to maintain host leukocyte transformation. Nature. 2015;520:378-82 pubmed 出版商

López de Figueroa P, Lotz M, Blanco F, Caramés B. Autophagy activation and protection from mitochondrial dysfunction in human chondrocytes. Arthritis Rheumatol. 2015;67:966-76 pubmed 出版商

Thomas Y, Peter M, Mechali F, Blanchard J, Coux O, Baldin V. Kizuna is a novel mitotic substrate for CDC25B phosphatase. Cell Cycle. 2014;13:3867-77 pubmed 出版商

Brandstaetter H, Kishi Itakura C, Tumbarello D, Manstein D, Buss F. Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion. Autophagy. 2014;10:2310-23 pubmed 出版商

Kim J, Ishiguro K, Nambu A, Akiyoshi B, Yokobayashi S, Kagami A, et al. Meikin is a conserved regulator of meiosis-I-specific kinetochore function. Nature. 2015;517:466-71 pubmed 出版商

Imajo M, Ebisuya M, Nishida E. Dual role of YAP and TAZ in renewal of the intestinal epithelium. Nat Cell Biol. 2015;17:7-19 pubmed 出版商

Ling X, Xu C, Fan C, Zhong K, Li F, Wang X. FL118 induces p53-dependent senescence in colorectal cancer cells by promoting degradation of MdmX. Cancer Res. 2014;74:7487-97 pubmed 出版商

Qiao X, Roth I, Féraille E, Hasler U. Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion. Cell Cycle. 2014;13:3059-75 pubmed 出版商

Li M, Bian C, Yu X. Poly(ADP-ribosyl)ation is recognized by ECT2 during mitosis. Cell Cycle. 2014;13:2944-51 pubmed 出版商

Hoon J, Li H, Koh C. POPX2 phosphatase regulates cell polarity and centrosome placement. Cell Cycle. 2014;13:2459-68 pubmed 出版商

Meng L, Ward A, Chun S, Bennett C, Beaudet A, Rigo F. Towards a therapy for Angelman syndrome by targeting a long non-coding RNA. Nature. 2015;518:409-12 pubmed 出版商

Pickholtz I, Saadyan S, Keshet G, Wang V, Cohen R, Bouwman P, et al. Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and growth inhibition of breast cancer cells and cancer stem-like cells. Oncotarget. 2014;5:11827-46 pubmed

Leyk J, Goldbaum O, Noack M, Richter Landsberg C. Inhibition of HDAC6 modifies tau inclusion body formation and impairs autophagic clearance. J Mol Neurosci. 2015;55:1031-46 pubmed 出版商

Green C, Fraser S, Day M. Insulin-like growth factor 1 increases apical fibronectin in blastocysts to increase blastocyst attachment to endometrial epithelial cells in vitro. Hum Reprod. 2015;30:284-98 pubmed 出版商

Boscia F, Passaro C, Gigantino V, Perdonà S, Franco R, Portella G, et al. High levels of GPR30 protein in human testicular carcinoma in situ and seminomas correlate with low levels of estrogen receptor-beta and indicate a switch in estrogen responsiveness. J Cell Physiol. 2015;230:1290-7 pubmed 出版商

Kararigas G, Fliegner D, Forler S, Klein O, Schubert C, Gustafsson J, et al. Comparative proteomic analysis reveals sex and estrogen receptor β effects in the pressure overloaded heart. J Proteome Res. 2014;13:5829-36 pubmed 出版商

Andlauer T, Scholz Kornehl S, Tian R, Kirchner M, Babikir H, Depner H, et al. Drep-2 is a novel synaptic protein important for learning and memory. elife. 2014;3: pubmed 出版商

Husedzinovic A, Neumann B, Reymann J, Draeger Meurer S, Chari A, Erfle H, et al. The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization. Mol Biol Cell. 2015;26:161-71 pubmed 出版商

Korobko E, Kiselev S, Korobko I. Characterization of Rabaptin-5 γ isoform. Biochemistry (Mosc). 2014;79:856-64 pubmed 出版商

Martínez Vega R, Garrido F, Partearroyo T, Cediel R, Zeisel S, Martínez Álvarez C, et al. Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism. FASEB J. 2015;29:418-32 pubmed 出版商

Katz Y, Li F, Lambert N, Sokol E, Tam W, Cheng A, et al. Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state. elife. 2014;3:e03915 pubmed 出版商

Israeli Rosenberg S, Chen C, Li R, Deussen D, Niesman I, Okada H, et al. Caveolin modulates integrin function and mechanical activation in the cardiomyocyte. FASEB J. 2015;29:374-84 pubmed 出版商

Kraus Y, Flici H, Hensel K, Plickert G, Leitz T, Frank U. The embryonic development of the cnidarian Hydractinia echinata. Evol Dev. 2014;16:323-38 pubmed 出版商

Mardilovich K, Gabrielsen M, McGarry L, Orange C, Patel R, Shanks E, et al. Elevated LIM kinase 1 in nonmetastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation. Mol Cancer Ther. 2015;14:246-58 pubmed 出版商

Bultema J, Boyle J, Malenke P, Martin F, Dell Angelica E, Cheney R, et al. Myosin vc interacts with Rab32 and Rab38 proteins and works in the biogenesis and secretion of melanosomes. J Biol Chem. 2014;289:33513-28 pubmed 出版商

Agircan F, Schiebel E. Sensors at centrosomes reveal determinants of local separase activity. PLoS Genet. 2014;10:e1004672 pubmed 出版商

Cabral G, Marques A, Schubert V, Pedrosa Harand A, Schlögelhofer P. Chiasmatic and achiasmatic inverted meiosis of plants with holocentric chromosomes. Nat Commun. 2014;5:5070 pubmed 出版商

Reese J, Suman V, Subramaniam M, Wu X, Negron V, Gingery A, et al. ERβ1: characterization, prognosis, and evaluation of treatment strategies in ERα-positive and -negative breast cancer. BMC Cancer. 2014;14:749 pubmed 出版商

Ilagan J, Ramakrishnan A, Hayes B, Murphy M, Zebari A, Bradley P, et al. U2AF1 mutations alter splice site recognition in hematological malignancies. Genome Res. 2015;25:14-26 pubmed 出版商

Jia D, Yang W, Li L, Liu H, Tan Y, Ooi S, et al. β-Catenin and NF-κB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer. Cell Death Differ. 2015;22:298-310 pubmed 出版商

Chan Y, West S. Spatial control of the GEN1 Holliday junction resolvase ensures genome stability. Nat Commun. 2014;5:4844 pubmed 出版商

Ribeiro Varandas E, Pereira H, Monteiro S, Neves E, Brito L, Ferreira R, et al. Bisphenol A disrupts transcription and decreases viability in aging vascular endothelial cells. Int J Mol Sci. 2014;15:15791-805 pubmed 出版商

Rocha C, Martins A, Rato L, Silva B, Oliveira P, Alves M. Melatonin alters the glycolytic profile of Sertoli cells: implications for male fertility. Mol Hum Reprod. 2014;20:1067-76 pubmed 出版商

Tao L, Chen C, Song H, Piccioni M, Shi G, Li B. Deubiquitination and stabilization of IL-33 by USP21. Int J Clin Exp Pathol. 2014;7:4930-7 pubmed

Liu J, Zheng L, Ma L, Wang B, Zhao Y, Wu N, et al. Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy. J Nutr Biochem. 2014;25:1154-1160 pubmed 出版商

Rotunno M, Auclair J, Maniatis S, Shaffer S, AGAR J, Bosco D. Identification of a misfolded region in superoxide dismutase 1 that is exposed in amyotrophic lateral sclerosis. J Biol Chem. 2014;289:28527-38 pubmed 出版商

Peng M, Emmadi R, Wang Z, Wiley E, Gann P, Khan S, et al. PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors. Oncotarget. 2014;5:6038-48 pubmed

Ishii H, Saitoh M, Sakamoto K, Kondo T, Katoh R, Tanaka S, et al. Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms. J Biol Chem. 2014;289:27386-99 pubmed 出版商

Passaro C, Volpe M, Botta G, Scamardella E, Perruolo G, Gillespie D, et al. PARP inhibitor olaparib increases the oncolytic activity of dl922-947 in in vitro and in vivo model of anaplastic thyroid carcinoma. Mol Oncol. 2015;9:78-92 pubmed 出版商

Xu M, Nagati J, Xie J, Li J, Walters H, Moon Y, et al. An acetate switch regulates stress erythropoiesis. Nat Med. 2014;20:1018-26 pubmed 出版商

James S, Banta T, Barra J, Ciraku L, Coile C, Cuda Z, et al. Restraint of the G2/M transition by the SR/RRM family mRNA shuttling binding protein SNXAHRB1 in Aspergillus nidulans. Genetics. 2014;198:617-33 pubmed 出版商

Lee Y, Santé J, Comerci C, Cyge B, Menezes L, Li F, et al. Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function. Mol Biol Cell. 2014;25:2919-33 pubmed 出版商

Isogaya K, Koinuma D, Tsutsumi S, Saito R, Miyazawa K, Aburatani H, et al. A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression. Cell Res. 2014;24:994-1008 pubmed 出版商

Smith C, Matheson T, Trombly D, Sun X, Campeau E, Han X, et al. A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli. Mol Biol Cell. 2014;25:2866-81 pubmed 出版商

Galletta B, Guillen R, Fagerstrom C, Brownlee C, Lerit D, Megraw T, et al. Drosophila pericentrin requires interaction with calmodulin for its function at centrosomes and neuronal basal bodies but not at sperm basal bodies. Mol Biol Cell. 2014;25:2682-94 pubmed 出版商

Nickerson K, Homer C, Kessler S, Dixon L, Kabi A, Gordon I, et al. The dietary polysaccharide maltodextrin promotes Salmonella survival and mucosal colonization in mice. PLoS ONE. 2014;9:e101789 pubmed 出版商

Lodato S, Molyneaux B, Zuccaro E, Goff L, Chen H, Yuan W, et al. Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Nat Neurosci. 2014;17:1046-54 pubmed 出版商

Hopkins J, Hwang G, Jacob J, Sapp N, Bedigian R, Oka K, et al. Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. PLoS Genet. 2014;10:e1004413 pubmed 出版商

Manguan García C, Pintado Berninches L, Carrillo J, Machado Pinilla R, Sastre L, Perez Quilis C, et al. Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells. PLoS ONE. 2014;9:e101424 pubmed 出版商

Takeda A, Oberoi Khanuja T, Glatz G, Schulenburg K, Scholz R, Carpy A, et al. Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1. EMBO J. 2014;33:1784-801 pubmed 出版商

O Rourke B, Gomez Ferreria M, Berk R, Hackl A, Nicholas M, O Rourke S, et al. Cep192 controls the balance of centrosome and non-centrosomal microtubules during interphase. PLoS ONE. 2014;9:e101001 pubmed 出版商

Kim D, Birendra K, Zhu W, Motamedchaboki K, Doye V, Roux K. Probing nuclear pore complex architecture with proximity-dependent biotinylation. Proc Natl Acad Sci U S A. 2014;111:E2453-61 pubmed 出版商

Soares F, Tattoli I, Rahman M, Robertson S, Belcheva A, Liu D, et al. The mitochondrial protein NLRX1 controls the balance between extrinsic and intrinsic apoptosis. J Biol Chem. 2014;289:19317-30 pubmed 出版商

Kielar M, Tuy F, Bizzotto S, Lebrand C, de Juan Romero C, Poirier K, et al. Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human. Nat Neurosci. 2014;17:923-33 pubmed 出版商

Li R, Tan J, Chen L, Feng J, Liang W, Guo X, et al. Iqcg is essential for sperm flagellum formation in mice. PLoS ONE. 2014;9:e98053 pubmed 出版商

Cheong F, Feng L, Sarkeshik A, Yates J, Schroer T. Dynactin integrity depends upon direct binding of dynamitin to Arp1. Mol Biol Cell. 2014;25:2171-80 pubmed 出版商

Kitagawa K, Shibata K, Matsumoto A, Matsumoto M, Ohhata T, Nakayama K, et al. Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development. Mol Cell Biol. 2014;34:2732-44 pubmed

Zavodszky E, Seaman M, Moreau K, Jimenez Sanchez M, Breusegem S, Harbour M, et al. Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy. Nat Commun. 2014;5:3828 pubmed 出版商

Shaw Hallgren G, Chmielarska Masoumi K, Zarrizi R, Hellman U, Karlsson P, Helou K, et al. Association of nuclear-localized Nemo-like kinase with heat-shock protein 27 inhibits apoptosis in human breast cancer cells. PLoS ONE. 2014;9:e96506 pubmed 出版商

Thoresen S, Campsteijn C, Vietri M, Schink K, Liestøl K, Andersen J, et al. ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4. Nat Cell Biol. 2014;16:550-60 pubmed 出版商

Garimella S, Gehlhaus K, Dine J, Pitt J, Grandin M, Chakka S, et al. Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening. Breast Cancer Res. 2014;16:R41 pubmed 出版商

Hayes S, Hng K, Clark P, Thistlethwaite F, Hawkins R, Ang Y. Immunohistochemical assessment of NY-ESO-1 expression in esophageal adenocarcinoma resection specimens. World J Gastroenterol. 2014;20:4011-6 pubmed 出版商

Touat Hamici Z, Legrain Y, Bulteau A, Chavatte L. Selective up-regulation of human selenoproteins in response to oxidative stress. J Biol Chem. 2014;289:14750-61 pubmed 出版商

Han X, Cheng D, Song F, Zeng T, An L, Xie K. Decelerated transport and its mechanism of 2,5-hexanedione on middle-molecular-weight neurofilament in rat dorsal root ganglia cells. Neuroscience. 2014;269:192-8 pubmed 出版商

Feuer S, Liu X, Donjacour A, Lin W, Simbulan R, Giritharan G, et al. Use of a mouse in vitro fertilization model to understand the developmental origins of health and disease hypothesis. Endocrinology. 2014;155:1956-69 pubmed 出版商

Kuo P, Huang Y, Hsieh C, Lee J, Lin B, Hung L. STK31 is a cell-cycle regulated protein that contributes to the tumorigenicity of epithelial cancer cells. PLoS ONE. 2014;9:e93303 pubmed 出版商

Rennoll S, Scott S, Yochum G. Targeted repression of AXIN2 and MYC gene expression using designer TALEs. Biochem Biophys Res Commun. 2014;446:1120-5 pubmed 出版商

Gunkel M, Flottmann B, Heilemann M, Reymann J, Erfle H. Integrated and correlative high-throughput and super-resolution microscopy. Histochem Cell Biol. 2014;141:597-603 pubmed 出版商

Mackeh R, Lorin S, Ratier A, Mejdoubi Charef N, Baillet A, Bruneel A, et al. Reactive oxygen species, AMP-activated protein kinase, and the transcription cofactor p300 regulate ?-tubulin acetyltransferase-1 (?TAT-1/MEC-17)-dependent microtubule hyperacetylation during cell stress. J Biol Chem. 2014;289:11816-28 pubmed 出版商

Herve D, Philippi A, Belbouab R, Zerah M, Chabrier S, Collardeau Frachon S, et al. Loss of ?1?1 soluble guanylate cyclase, the major nitric oxide receptor, leads to moyamoya and achalasia. Am J Hum Genet. 2014;94:385-94 pubmed 出版商

Imamura K, Maeda S, Kawamura I, Matsuyama K, Shinohara N, Yahiro Y, et al. Human immunodeficiency virus type 1 enhancer-binding protein 3 is essential for the expression of asparagine-linked glycosylation 2 in the regulation of osteoblast and chondrocyte differentiation. J Biol Chem. 2014;289:9865-79 pubmed 出版商

Uno M, Saitoh Y, Mochida K, Tsuruyama E, Kiyono T, Imoto I, et al. NF-?B inducing kinase, a central signaling component of the non-canonical pathway of NF-?B, contributes to ovarian cancer progression. PLoS ONE. 2014;9:e88347 pubmed 出版商

Ryszawy D, Sarna M, Rak M, Szpak K, Kedracka Krok S, Michalik M, et al. Functional links between Snail-1 and Cx43 account for the recruitment of Cx43-positive cells into the invasive front of prostate cancer. Carcinogenesis. 2014;35:1920-30 pubmed 出版商

Wong Y, Holzbaur E. The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation. J Neurosci. 2014;34:1293-305 pubmed 出版商

Xu C, Fan C, Wang X. Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase. Oncogene. 2015;34:281-9 pubmed 出版商

Sike A, Nagy E, Vedelek B, Pusztai D, Szerémy P, Venetianer A, et al. mRNA levels of related Abcb genes change opposite to each other upon histone deacetylase inhibition in drug-resistant rat hepatoma cells. PLoS ONE. 2014;9:e84915 pubmed 出版商

Manil Ségalen M, Culetto E, Legouis R, Lefebvre C. Interactions between endosomal maturation and autophagy: analysis of ESCRT machinery during Caenorhabditis elegans development. Methods Enzymol. 2014;534:93-118 pubmed 出版商

Klinger M, Wang W, Kuhns S, Bärenz F, Dräger Meurer S, Pereira G, et al. The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone. Mol Biol Cell. 2014;25:495-507 pubmed 出版商

Sharma Walia N, Chandran K, Patel K, Veettil M, Marginean A. The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis. J Virol. 2014;88:2131-56 pubmed 出版商

Mielcarek M, Landles C, Weiss A, Bradaia A, Seredenina T, Inuabasi L, et al. HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration. PLoS Biol. 2013;11:e1001717 pubmed 出版商

Rennoll S, Konsavage W, Yochum G. Nuclear AXIN2 represses MYC gene expression. Biochem Biophys Res Commun. 2014;443:217-22 pubmed 出版商

Tan S, Shui G, Zhou J, Shi Y, Huang J, Xia D, et al. Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway. Autophagy. 2014;10:226-42 pubmed 出版商

Alves M, Martins A, Vaz C, Correia S, Moreira P, Oliveira P, et al. Metformin and male reproduction: effects on Sertoli cell metabolism. Br J Pharmacol. 2014;171:1033-42 pubmed 出版商

Cochrane A. HIV-1 Rev function and RNA nuclear-cytoplasmic export. Methods Mol Biol. 2014;1087:103-14 pubmed 出版商

Garcia E, Santana Martínez R, Silva Islas C, Colín González A, Galvan Arzate S, Heras Y, et al. S-allyl cysteine protects against MPTP-induced striatal and nigral oxidative neurotoxicity in mice: participation of Nrf2. Free Radic Res. 2014;48:159-67 pubmed 出版商

Aukkarasongsup P, Haruyama N, Matsumoto T, Shiga M, Moriyama K. Periostin inhibits hypoxia-induced apoptosis in human periodontal ligament cells via TGF-? signaling. Biochem Biophys Res Commun. 2013;441:126-32 pubmed 出版商

Hashizume C, Kobayashi A, Wong R. Down-modulation of nucleoporin RanBP2/Nup358 impaired chromosomal alignment and induced mitotic catastrophe. Cell Death Dis. 2013;4:e854 pubmed 出版商

Hashizume C, Moyori A, Kobayashi A, Yamakoshi N, Endo A, Wong R. Nucleoporin Nup62 maintains centrosome homeostasis. Cell Cycle. 2013;12:3804-16 pubmed 出版商

Martinez Sanchez A, Murphy C. miR-1247 functions by targeting cartilage transcription factor SOX9. J Biol Chem. 2013;288:30802-14 pubmed 出版商

Kim Y, Zheng Y. Generation and characterization of a conditional deletion allele for Lmna in mice. Biochem Biophys Res Commun. 2013;440:8-13 pubmed 出版商

Chen Y, Kamili A, Hardy J, Groblewski G, Khanna K, Byrne J. Tumor protein D52 represents a negative regulator of ATM protein levels. Cell Cycle. 2013;12:3083-97 pubmed 出版商

Horton J, Stefanick D, Gassman N, Williams J, Gabel S, Cuneo M, et al. Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses. DNA Repair (Amst). 2013;12:774-85 pubmed 出版商

Yuki K, Yoshida T, Miyake S, Tsubota K, Ozawa Y. Neuroprotective role of superoxide dismutase 1 in retinal ganglion cells and inner nuclear layer cells against N-methyl-d-aspartate-induced cytotoxicity. Exp Eye Res. 2013;115:230-8 pubmed 出版商

Alfonso Pérez T, Domínguez Sánchez M, Garcia Dominguez M, Reyes J. Cytoplasmic interaction of the tumour suppressor protein hSNF5 with dynamin-2 controls endocytosis. Oncogene. 2014;33:3064-74 pubmed 出版商

Walser R, Burke J, Gogvadze E, Bohnacker T, Zhang X, Hess D, et al. PKC? phosphorylates PI3K? to activate it and release it from GPCR control. PLoS Biol. 2013;11:e1001587 pubmed 出版商

Zhang L, Wahlin K, Li Y, Masuda T, Yang Z, Zack D, et al. RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors. Mol Vis. 2013;19:1371-86 pubmed

Maddaluno L, Rudini N, Cuttano R, Bravi L, Giampietro C, Corada M, et al. EndMT contributes to the onset and progression of cerebral cavernous malformations. Nature. 2013;498:492-6 pubmed 出版商

Samwer M, Dehne H, Spira F, Kollmar M, Gerlich D, Urlaub H, et al. The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO J. 2013;32:1886-902 pubmed 出版商

Brochier C, Dennis G, Rivieccio M, McLaughlin K, Coppola G, Ratan R, et al. Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. J Neurosci. 2013;33:8621-32 pubmed 出版商

Grabole N, Tischler J, Hackett J, Kim S, Tang F, Leitch H, et al. Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation. EMBO Rep. 2013;14:629-37 pubmed 出版商

Moreno A, Soleto I, García Sanz P, Moreno Bueno G, Palmero I. ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth. Oncogene. 2014;33:1945-53 pubmed 出版商

Reginensi A, Scott R, Gregorieff A, Bagherie Lachidan M, Chung C, Lim D, et al. Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development. PLoS Genet. 2013;9:e1003380 pubmed 出版商

Luo M, Ling T, Xie W, Sun H, Zhou Y, Zhu Q, et al. NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells. Stem Cells. 2013;31:1278-86 pubmed 出版商

Dush M, Nascone Yoder N. Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut. Development. 2013;140:1457-66 pubmed 出版商

Trakala M, Fernández Miranda G, Perez de Castro I, Heeschen C, Malumbres M. Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1). Cell Cycle. 2013;12:1030-41 pubmed 出版商

Peng X, Gao H, Wang Y, Yang B, Liu T, Sun Y, et al. Conversion of rat embryonic stem cells into neural precursors in chemical-defined medium. Biochem Biophys Res Commun. 2013;431:783-7 pubmed 出版商

Gu B, Eick D, Bensaude O. CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo. Nucleic Acids Res. 2013;41:1591-603 pubmed 出版商

Tattoli I, Philpott D, Girardin S. The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole. Biol Open. 2012;1:1215-25 pubmed 出版商

Newman A, Scholefield C, Kemp A, Newman M, McIver E, Kamal A, et al. TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling. PLoS ONE. 2012;7:e50672 pubmed 出版商

Fan C, Lum M, Xu C, Black J, Wang X. Ubiquitin-dependent regulation of phospho-AKT dynamics by the ubiquitin E3 ligase, NEDD4-1, in the insulin-like growth factor-1 response. J Biol Chem. 2013;288:1674-84 pubmed 出版商

Jullien L, Mestre M, Roux P, Gire V. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response. Nucleic Acids Res. 2013;41:900-11 pubmed 出版商

Gao M, Rendtlew Danielsen J, Wei L, Zhou D, Xu Q, Li M, et al. A novel role of human holliday junction resolvase GEN1 in the maintenance of centrosome integrity. PLoS ONE. 2012;7:e49687 pubmed 出版商

Ribeiro Varandas E, Viegas W, Sofia Pereira H, Delgado M. Bisphenol A at concentrations found in human serum induces aneugenic effects in endothelial cells. Mutat Res. 2013;751:27-33 pubmed 出版商

Aivar P, Fernandez Orth J, Gomis Pèrez C, Alberdi A, Alaimo A, Rodriguez M, et al. Surface expression and subunit specific control of steady protein levels by the Kv7.2 helix A-B linker. PLoS ONE. 2012;7:e47263 pubmed 出版商

Dinh P, Beura L, Das P, Panda D, Das A, Pattnaik A. Induction of stress granule-like structures in vesicular stomatitis virus-infected cells. J Virol. 2013;87:372-83 pubmed 出版商

Coffey K, Blackburn T, Cook S, Golding B, Griffin R, Hardcastle I, et al. Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. PLoS ONE. 2012;7:e45539 pubmed 出版商

Pakala S, Nair V, Reddy S, Kumar R. Signaling-dependent phosphorylation of mitotic centromere-associated kinesin regulates microtubule depolymerization and its centrosomal localization. J Biol Chem. 2012;287:40560-9 pubmed 出版商

Hebras C, McDougall A. Urochordate ascidians possess a single isoform of Aurora kinase that localizes to the midbody via TPX2 in eggs and cleavage stage embryos. PLoS ONE. 2012;7:e45431 pubmed 出版商

Wallmen B, Schrempp M, Hecht A. Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/?-catenin target gene expression. Nucleic Acids Res. 2012;40:9455-69 pubmed 出版商

Ma M, Chircop M. SNX9, SNX18 and SNX33 are required for progression through and completion of mitosis. J Cell Sci. 2012;125:4372-82 pubmed 出版商

Liu K, Wang H, Long Y, Ye J, Yuan L. Coordinate lentiviral expression of Cre recombinase and RFP/EGFP mediated by FMDV 2A and analysis of Cre activity. J Cell Biochem. 2012;113:2909-19 pubmed 出版商

Shia W, Okumura A, Yan M, Sarkeshik A, Lo M, Matsuura S, et al. PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential. Blood. 2012;119:4953-62 pubmed 出版商

Mikeladze Dvali T, von Tobel L, Strnad P, Knott G, Leonhardt H, Schermelleh L, et al. Analysis of centriole elimination during C. elegans oogenesis. Development. 2012;139:1670-9 pubmed 出版商

Austenaa L, Barozzi I, Chronowska A, Termanini A, Ostuni R, Prosperini E, et al. The histone methyltransferase Wbp7 controls macrophage function through GPI glycolipid anchor synthesis. Immunity. 2012;36:572-85 pubmed 出版商

Herz H, Mohan M, Garrett A, Miller C, Casto D, Zhang Y, et al. Polycomb repressive complex 2-dependent and -independent functions of Jarid2 in transcriptional regulation in Drosophila. Mol Cell Biol. 2012;32:1683-93 pubmed 出版商

Houben A, Kumke K, Nagaki K, Hause G. CENH3 distribution and differential chromatin modifications during pollen development in rye (Secale cereale L.). Chromosome Res. 2011;19:471-80 pubmed 出版商

Clarke J, Emson P, Irvine R. Distribution and neuronal expression of phosphatidylinositol phosphate kinase IIgamma in the mouse brain. J Comp Neurol. 2009;517:296-312 pubmed 出版商

Jin L, Zhang G, Jamison C, Takano H, Haydon P, Selzer M. Axon regeneration in the absence of growth cones: acceleration by cyclic AMP. J Comp Neurol. 2009;515:295-312 pubmed 出版商

Ramsey C, Yeung F, Stoddard P, Li D, Creutz C, Mayo M. Copine-I represses NF-kappaB transcription by endoproteolysis of p65. Oncogene. 2008;27:3516-26 pubmed 出版商

Young D, Jonnalagadda J, Gatei M, Jans D, Meyn S, Khanna K. Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association. J Biol Chem. 2005;280:27587-94 pubmed

Madison D, Yaciuk P, Kwok R, Lundblad J. Acetylation of the adenovirus-transforming protein E1A determines nuclear localization by disrupting association with importin-alpha. J Biol Chem. 2002;277:38755-63 pubmed

Cisneros Aguirre M, Lopezcolorado F, Tsai L, Bhargava R, Stark J. The importance of DNAPKcs for blunt DNA end joining is magnified when XLF is weakened. Nat Commun. 2022;13:3662 pubmed 出版商

Moalem Y, Malis Y, Voloshin K, Dukhovny A, Hirschberg K, Sklan E. Sandfly Fever Viruses Attenuate the Type I Interferon Response by Targeting the Phosphorylation of JAK-STAT Components. Front Immunol. 2022;13:865797 pubmed 出版商

Wang Y, Ma B, Liu X, Gao G, Che Z, Fan M, et al. ZFP281-BRCA2 prevents R-loop accumulation during DNA replication. Nat Commun. 2022;13:3493 pubmed 出版商

Marchi P, Marrone L, Brasseur L, Coens A, Webster C, Bousset L, et al. C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons. Life Sci Alliance. 2022;5: pubmed 出版商

Mac Kain A, Maarifi G, Aicher S, Arhel N, Baidaliuk A, Munier S, et al. Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen. Nat Commun. 2022;13:2442 pubmed 出版商

Courtellemont T, De Leo M, Gopaldass N, Mayer A. CROP: a retromer-PROPPIN complex mediating membrane fission in the endo-lysosomal system. EMBO J. 2022;41:e109646 pubmed 出版商

Cabello Lobato M, Jenner M, Cisneros Aguirre M, Brüninghoff K, Sandy Z, da Costa I, et al. Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining. Nucleic Acids Res. 2022;50:4732-4754 pubmed 出版商

Sathyanarayana S, Saunders J, Slaughter J, Tariq K, Chakrabarti R, Sadanandappa M, et al. Pten heterozygosity restores neuronal morphology in fragile X syndrome mice. Proc Natl Acad Sci U S A. 2022;119:e2109448119 pubmed 出版商

Haimovici A, Hofer C, Badr M, Bavafaye Haghighi E, Amer T, Boerries M, et al. Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse. Cell Death Dis. 2022;13:315 pubmed 出版商

Gogleva A, Polychronopoulos D, Pfeifer M, Poroshin V, Ughetto M, Martin M, et al. Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer. Nat Commun. 2022;13:1667 pubmed 出版商

Takenoshita Y, Hara M, Fukagawa T. Recruitment of two Ndc80 complexes via the CENP-T pathway is sufficient for kinetochore functions. Nat Commun. 2022;13:851 pubmed 出版商

Tan M, Li S, Juillard F, Chitas R, Custodio T, Xue H, et al. MLL1 is regulated by KSHV LANA and is important for virus latency. Nucleic Acids Res. 2021;49:12895-12911 pubmed 出版商

Park S, Frake R, Karabiyik C, Son S, Siddiqi F, Bento C, et al. Vinexin contributes to autophagic decline in brain ageing across species. Cell Death Differ. 2021;: pubmed 出版商

Wang L, Proulx M, Kim A, Lelarge V, McCaffrey L. A proximity proteomics screen in three-dimensional spheroid cultures identifies novel regulators of lumen formation. Sci Rep. 2021;11:22807 pubmed 出版商

Nie L, He K, Xie F, Xiao S, Li S, Xu J, et al. Loganin substantially ameliorates molecular deficits, pathologies and cognitive impairment in a mouse model of Alzheimer's disease. Aging (Albany NY). 2021;13:23739-23756 pubmed 出版商

Basic M, Hertel A, Bajdzienko J, Bonn F, Tellechea M, Stolz A, et al. The deubiquitinase USP11 is a versatile and conserved regulator of autophagy. J Biol Chem. 2021;297:101263 pubmed 出版商

Soto Faguás C, Sanchez Molina P, Saura C. Loss of presenilin function enhances tau phosphorylation and aggregation in mice. Acta Neuropathol Commun. 2021;9:162 pubmed 出版商

Evron T, Caspi M, Kazelnik M, Shor Nareznoy Y, Armoza Eilat S, Kariv R, et al. A CRISPR knockout screen reveals new regulators of canonical Wnt signaling. Oncogenesis. 2021;10:63 pubmed 出版商

Nicholas T, Metcalf S, Greulich B, Hollenhorst P. Androgen signaling connects short isoform production to breakpoint formation at Ewing sarcoma breakpoint region 1. NAR Cancer. 2021;3:zcab033 pubmed 出版商

Olbrich T, Vega Sendino M, Tillo D, Wu W, Zolnerowich N, Pavani R, et al. CTCF is a barrier for 2C-like reprogramming. Nat Commun. 2021;12:4856 pubmed 出版商

Feliciano D, Ott C, Espinosa Medina I, Weigel A, Benedetti L, Milano K, et al. YAP1 nuclear efflux and transcriptional reprograming follow membrane diminution upon VSV-G-induced cell fusion. Nat Commun. 2021;12:4502 pubmed 出版商

Nowicka U, Chrościcki P, Stroobants K, Sladowska M, Turek M, Uszczynska Ratajczak B, et al. Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins. elife. 2021;10: pubmed 出版商

Li M, McGhee E, Shinno L, Lee K, Lin Y. Exposure to Microbial Metabolite Butyrate Prolongs the Survival Time and Changes the Growth Pattern of Human Papillomavirus 16 E6/E7-Immortalized Keratinocytes in Vivo. Am J Pathol. 2021;191:1822-1836 pubmed 出版商

Ramirez Alvarez C, Kee C, Sharma A, Thomas L, Schmidt F, Stanifer M, et al. The endogenous cellular protease inhibitor SPINT2 controls SARS-CoV-2 viral infection and is associated to disease severity. PLoS Pathog. 2021;17:e1009687 pubmed 出版商

Zhang J, He X, Wu H, Zhang X, Yang S, Liu C, et al. Loss of DRC1 function leads to multiple morphological abnormalities of the sperm flagella and male infertility in human and mouse. Hum Mol Genet. 2021;: pubmed 出版商

Hatzopoulos G, Kükenshöner T, Banterle N, Favez T, Flückiger I, Hamel V, et al. Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly. Nat Commun. 2021;12:3805 pubmed 出版商

Dahlet T, Truss M, Frede U, Al Adhami H, Bardet A, Dumas M, et al. E2F6 initiates stable epigenetic silencing of germline genes during embryonic development. Nat Commun. 2021;12:3582 pubmed 出版商

Scott G, Mahoney S, Scott M, Loureiro A, Lopez Ramirez A, Tanner J, et al. N-Propargylglycine: a unique suicide inhibitor of proline dehydrogenase with anticancer activity and brain-enhancing mitohormesis properties. Amino Acids. 2021;53:1927-1939 pubmed 出版商

Wright G, Sonavane M, Gassman N. Activated STAT3 Is a Novel Regulator of the XRCC1 Promoter and Selectively Increases XRCC1 Protein Levels in Triple Negative Breast Cancer. Int J Mol Sci. 2021;22: pubmed 出版商

Meyer F, Goebel S, Spangel S, Leovsky C, Hoelzer D, Thierbach R. Metformin alters therapeutic effects in the BALB/c tumor therapy model. BMC Cancer. 2021;21:629 pubmed 出版商

Bi Y, Chen X, Wei B, Wang L, Gong L, Li H, et al. DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells. Theranostics. 2021;11:6355-6369 pubmed 出版商

Kochanowski P, Catapano J, Pudełek M, Wrobel T, Madeja Z, Ryszawy D, et al. Temozolomide Induces the Acquisition of Invasive Phenotype by O6-Methylguanine-DNA Methyltransferase (MGMT)+ Glioblastoma Cells in a Snail-1/Cx43-Dependent Manner. Int J Mol Sci. 2021;22: pubmed 出版商

Klouwer F, Falkenberg K, Ofman R, Koster J, van Gent D, Ferdinandusse S, et al. Autophagy Inhibitors Do Not Restore Peroxisomal Functions in Cells With the Most Common Peroxisome Biogenesis Defect. Front Cell Dev Biol. 2021;9:661298 pubmed 出版商

Michaluk P, Heller J, Rusakov D. Rapid recycling of glutamate transporters on the astroglial surface. elife. 2021;10: pubmed 出版商

Herrero Ruíz A, Martínez García P, Terron Bautista J, Millán Zambrano G, Lieberman J, Jimeno González S, et al. Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing. Cell Rep. 2021;35:108977 pubmed 出版商

Giebel N, de Jaime Soguero A, García Del Arco A, Landry J, Tietje M, Villacorta L, et al. USP42 protects ZNRF3/RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling. EMBO Rep. 2021;22:e51415 pubmed 出版商

Fujino T, Goyama S, Sugiura Y, Inoue D, Asada S, Yamasaki S, et al. Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway. Nat Commun. 2021;12:1826 pubmed 出版商

Baxley R, Leung W, Schmit M, Matson J, Yin L, Oram M, et al. Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening. Nat Commun. 2021;12:1626 pubmed 出版商

Liu L, Lauro B, Wolfe M, Selkoe D. Hydrophilic loop 1 of Presenilin-1 and the APP GxxxG transmembrane motif regulate γ-secretase function in generating Alzheimer-causing Aβ peptides. J Biol Chem. 2021;296:100393 pubmed 出版商

Miskin R, Warren J, Ndoye A, Wu L, Lamar J, DiPersio C. Integrin α3β1 Promotes Invasive and Metastatic Properties of Breast Cancer Cells through Induction of the Brn-2 Transcription Factor. Cancers (Basel). 2021;13: pubmed 出版商

Chen T, Huang B, Tang T, Chao Y, Xiao X, Lee P, et al. Genotoxic stress-activated DNA-PK-p53 cascade and autophagy cooperatively induce ciliogenesis to maintain the DNA damage response. Cell Death Differ. 2021;: pubmed 出版商

Fan X, Zeng Y, Fan Z, Cui L, Song W, Wu Q, et al. Dihydromyricetin promotes longevity and activates the transcription factors FOXO and AOP in Drosophila. Aging (Albany NY). 2020;13:460-476 pubmed 出版商

Hachimi M, Grabowski C, Campanario S, Herranz G, Baonza G, Serrador J, et al. Smoothelin-like 2 Inhibits Coronin-1B to Stabilize the Apical Actin Cortex during Epithelial Morphogenesis. Curr Biol. 2020;: pubmed 出版商

Cui L, Song W, Zeng Y, Wu Q, Fan Z, Huang T, et al. Deubiquitinase USP7 regulates Drosophila aging through ubiquitination and autophagy. Aging (Albany NY). 2020;12:23082-23095 pubmed 出版商

Tomorsky J, Parker P, Doe C, Niell C. Precise levels of nectin-3 are required for proper synapse formation in postnatal visual cortex. Neural Dev. 2020;15:13 pubmed 出版商

Ebert K, Zwingenberger G, Barbaria E, Keller S, Heck C, Arnold R, et al. Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines. BMC Cancer. 2020;20:1039 pubmed 出版商

Saldana Caboverde A, Nissanka N, Garcia S, Lombes A, Diaz F. Hypoxia Promotes Mitochondrial Complex I Abundance via HIF-1α in Complex III and Complex IV Eficient Cells. Cells. 2020;9: pubmed 出版商

Chakravarti D, Hu B, Mao X, Rashid A, Li J, Li J, et al. Telomere dysfunction activates YAP1 to drive tissue inflammation. Nat Commun. 2020;11:4766 pubmed 出版商

He Z, Duan Z, Chen L, Li B, Zhou Y. Long non-coding RNA Loc490 inhibits gastric cancer cell proliferation and metastasis by upregulating RNA-binding protein Quaking. Aging (Albany NY). 2020;12:17681-17693 pubmed 出版商

Chen Y, Zhang P, Lin X, Zhang H, Miao J, Zhou Y, et al. Mitophagy impairment is involved in sevoflurane-induced cognitive dysfunction in aged rats. Aging (Albany NY). 2020;12:17235-17256 pubmed 出版商

Nakazawa K, Shichino Y, Iwasaki S, Shiina N. Implications of RNG140 (caprin2)-mediated translational regulation in eye lens differentiation. J Biol Chem. 2020;295:15029-15044 pubmed 出版商

Shen J, Zhu X, Liu H. MiR-483 induces senescence of human adipose-derived mesenchymal stem cells through IGF1 inhibition. Aging (Albany NY). 2020;12:15756-15770 pubmed 出版商

Yang R, Zhan M, Guo M, Yuan H, Wang Y, Zhang Y, et al. Yolk sac-derived Pdcd11-positive cells modulate zebrafish microglia differentiation through the NF-κB-Tgfβ1 pathway. Cell Death Differ. 2020;: pubmed 出版商

Muller A, Dickmanns A, Resch C, Schakel K, Hailfinger S, Dobbelstein M, et al. The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. J Clin Invest. 2020;: pubmed 出版商

Geisinger J, Stearns T. CRISPR/Cas9 treatment causes extended TP53-dependent cell cycle arrest in human cells. Nucleic Acids Res. 2020;48:9067-9081 pubmed 出版商

Bobkov G, Huang A, van den Berg S, Mitra S, Anselm E, Lazou V, et al. Spt6 is a maintenance factor for centromeric CENP-A. Nat Commun. 2020;11:2919 pubmed 出版商

Bae B, Gruner H, Lynch M, Feng T, So K, Oliver D, et al. Elimination of Calm1 long 3' UTR mRNA isoform by CRISPR-Cas9 gene editing impairs dorsal root ganglion development and hippocampal neuron activation in mice. RNA. 2020;: pubmed 出版商

Penas C, Apraiz A, Muñoa I, Arroyo Berdugo Y, Rasero J, Ezkurra P, et al. RKIP Regulates Differentiation-Related Features in Melanocytic Cells. Cancers (Basel). 2020;12: pubmed 出版商

Yang A, Shao T, Bofill De Ros X, Lian C, Villanueva P, Dai L, et al. AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2. Nat Commun. 2020;11:2765 pubmed 出版商

Valbuena Perez J, Linnenberger R, Dembek A, Bruscoli S, Riccardi C, Schulz M, et al. Altered glucocorticoid metabolism represents a feature of macroph-aging. Aging Cell. 2020;19:e13156 pubmed 出版商

Bai G, Kermi C, Stoy H, Schiltz C, Bacal J, Zaino A, et al. HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis. Mol Cell. 2020;78:1237-1251.e7 pubmed 出版商

Rickman K, Noonan R, Lach F, Sridhar S, Wang A, Abhyankar A, et al. Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links. Genes Dev. 2020;34:832-846 pubmed 出版商

Kiepas A, Voorand E, Senecal J, Ahn R, Annis M, Jacquet K, et al. The SHCA adapter protein cooperates with lipoma-preferred partner in the regulation of adhesion dynamics and invadopodia formation. J Biol Chem. 2020;: pubmed 出版商

D Souza R, Woodhead J, Hedges C, Zeng N, Wan J, Kumagai H, et al. Increased expression of the mitochondrial derived peptide, MOTS-c, in skeletal muscle of healthy aging men is associated with myofiber composition. Aging (Albany NY). 2020;12:5244-5258 pubmed 出版商

Nishiyama A, Mulholland C, Bultmann S, Kori S, Endo A, Saeki Y, et al. Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nat Commun. 2020;11:1222 pubmed 出版商

Luo H, Yu Q, Liu Y, Tang M, Liang M, Zhang D, et al. LATS kinase-mediated CTCF phosphorylation and selective loss of genomic binding. Sci Adv. 2020;6:eaaw4651 pubmed 出版商

Wang Y, Maeda Y, Liu Y, Takada Y, Ninomiya A, Hirata T, et al. Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation. Nat Commun. 2020;11:860 pubmed 出版商

Gulmez Karaca K, Kupke J, Brito D, Zeuch B, Thome C, Weichenhan D, et al. Neuronal ensemble-specific DNA methylation strengthens engram stability. Nat Commun. 2020;11:639 pubmed 出版商

Mitra S, Bodor D, David A, Abdul Zani I, Mata J, Neumann B, et al. Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin. Nat Commun. 2020;11:501 pubmed 出版商

Turchi R, Tortolici F, Guidobaldi G, Iacovelli F, Falconi M, Rufini S, et al. Frataxin deficiency induces lipid accumulation and affects thermogenesis in brown adipose tissue. Cell Death Dis. 2020;11:51 pubmed 出版商

An H, Fan C, Sharif M, Kim D, Poitelon Y, Park Y. Functional mechanism and pathogenic potential of MYRF ICA domain mutations implicated in birth defects. Sci Rep. 2020;10:814 pubmed 出版商

Shan S, Xu F, Bleyer M, Becker S, Melbaum T, Wemheuer W, et al. Association of α/β-Hydrolase D16B with Bovine Conception Rate and Sperm Plasma Membrane Lipid Composition. Int J Mol Sci. 2020;21: pubmed 出版商

Ramos H, Calheiros J, Almeida J, Barcherini V, Santos S, Carvalho A, et al. SLMP53-1 Inhibits Tumor Cell Growth through Regulation of Glucose Metabolism and Angiogenesis in a P53-Dependent Manner. Int J Mol Sci. 2020;21: pubmed 出版商

Zhang S, Liu Y, Huang Q, Yuan S, Liu H, Shi L, et al. Murine germ cell-specific disruption of Ift172 causes defects in spermiogenesis and male fertility. Reproduction. 2020;159:409-421 pubmed 出版商

Wang D, Wu H, Phua S, Yang G, Qi Lim W, Gu L, et al. Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor. Nat Commun. 2020;11:357 pubmed 出版商

Emidio G, Placidi M, Rea F, Rossi G, Falone S, Cristiano L, et al. Methylglyoxal-Dependent Glycative Stress and Deregulation of SIRT1 Functional Network in the Ovary of PCOS Mice. Cells. 2020;9: pubmed 出版商

Hanniford D, Ulloa Morales A, Karz A, Berzoti Coelho M, Moubarak R, Sánchez Sendra B, et al. Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis. Cancer Cell. 2020;37:55-70.e15 pubmed 出版商

Duan Y, Qiu Y, Huang X, Dai C, Yang J, He W. Deletion of FHL2 in fibroblasts attenuates fibroblasts activation and kidney fibrosis via restraining TGF-β1-induced Wnt/β-catenin signaling. J Mol Med (Berl). 2020;98:291-307 pubmed 出版商

Iaea D, Spahr Z, Singh R, Chan R, Zhou B, Bareja R, et al. Stable reduction of STARD4 alters cholesterol regulation and lipid homeostasis. Biochim Biophys Acta Mol Cell Biol Lipids. 2020;1865:158609 pubmed 出版商

Fierro Fernández M, Miguel V, Marquez Exposito L, Nuevo Tapioles C, Herrero J, Blanco Ruiz E, et al. MiR-9-5p protects from kidney fibrosis by metabolic reprogramming. FASEB J. 2020;34:410-431 pubmed 出版商

You E, Ko P, Jeong J, Keum S, Kim J, Seo Y, et al. Dynein-mediated nuclear translocation of yes-associated protein through microtubule acetylation controls fibroblast activation. Cell Mol Life Sci. 2020;: pubmed 出版商

Kundu A, Shelar S, Ghosh A, Ballestas M, Kirkman R, Nam H, et al. 14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation. J Biol Chem. 2020;295:1754-1766 pubmed 出版商

Chao A, Chen C, Wu M, Hou B, Yang D. Roles of Id1/HIF-1 and CDK5/HIF-1 in cell cycle reentry induced by amyloid-beta peptide in post-mitotic cortical neuron. Biochim Biophys Acta Mol Cell Res. 2020;1867:118628 pubmed 出版商

Nguyen A, Zhou J, Sicairos B, Sonney S, Du Y. Upregulation of CD73 Confers Acquired Radioresistance and is Required for Maintaining Irradiation-selected Pancreatic Cancer Cells in a Mesenchymal State. Mol Cell Proteomics. 2020;19:375-389 pubmed 出版商

Di M, Wang M, Miao J, Chen B, Huang H, Lin C, et al. CHAF1B induces radioresistance by promoting DNA damage repair in nasopharyngeal carcinoma. Biomed Pharmacother. 2020;123:109748 pubmed 出版商

Vymětalová L, Kučírková T, Knopfova L, Pospíšilová V, Kasko T, Lejdarova H, et al. Large-Scale Automated Hollow-Fiber Bioreactor Expansion of Umbilical Cord-Derived Human Mesenchymal Stromal Cells for Neurological Disorders. Neurochem Res. 2020;45:204-214 pubmed 出版商

Zhang S, Zhang J, Wei D, An H, Liu W, Lai Y, et al. Dengzhan Shengmai capsules and their active component scutellarin prevent cognitive decline in APP/PS1 mice by accelerating Aβ aggregation and reducing oligomers formation. Biomed Pharmacother. 2020;121:109682 pubmed 出版商

Oshima M, Pechberty S, Bellini L, Gopel S, Campana M, Rouch C, et al. Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity. Diabetologia. 2020;63:395-409 pubmed 出版商

Palese F, Bonomi E, Nuzzo T, Benussi A, Mellone M, Zianni E, et al. Anti-GluA3 antibodies in frontotemporal dementia: effects on glutamatergic neurotransmission and synaptic failure. Neurobiol Aging. 2020;86:143-155 pubmed 出版商

Kowal J, Schmal H, Halekoh U, Hjelmborg J, Kassem M. Single-cell high-content imaging parameters predict functional phenotype of cultured human bone marrow stromal stem cells. Stem Cells Transl Med. 2020;9:189-202 pubmed 出版商

Tan J, Fourrière L, Wang J, Perez F, Boncompain G, Gleeson P. Distinct anterograde trafficking pathways of BACE1 and amyloid precursor protein from the TGN and the regulation of amyloid-β production. Mol Biol Cell. 2020;31:27-44 pubmed 出版商

Alsabban A, Morikawa M, Tanaka Y, Takei Y, Hirokawa N. Kinesin Kif3b mutation reduces NMDAR subunit NR2A trafficking and causes schizophrenia-like phenotypes in mice. EMBO J. 2020;39:e101090 pubmed 出版商

Xu X, Eshima S, Kato S, Fisher D, Sakurai H, Hayakawa Y, et al. Rational Combination Therapy for Melanoma with Dinaciclib by Targeting BAK-Dependent Cell Death. Mol Cancer Ther. 2020;19:627-636 pubmed 出版商

Sieben C, Jeganathan K, Nelson G, Sturmlechner I, Zhang C, van Deursen W, et al. BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome. J Clin Invest. 2020;130:171-188 pubmed 出版商

Oh J, Park E, Song K, Bae G, Choi G. PHYTOCHROME INTERACTING FACTOR8 Inhibits Phytochrome A-Mediated Far-Red Light Responses in Arabidopsis. Plant Cell. 2020;32:186-205 pubmed 出版商

Jubrail J, Africano Gomez K, Herit F, Mularski A, Bourdoncle P, Oberg L, et al. Arpin is critical for phagocytosis in macrophages and is targeted by human rhinovirus. EMBO Rep. 2020;21:e47963 pubmed 出版商

Pistono C, Monti M, Boiocchi C, Berzolari F, Osera C, Mallucci G, et al. Response to oxidative stress of peripheral blood mononuclear cells from multiple sclerosis patients and healthy controls. Cell Stress Chaperones. 2020;25:81-91 pubmed 出版商

Herhaus L, Bhaskara R, Lystad A, Gestal Mato U, Covarrubias Pinto A, Bonn F, et al. TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease. EMBO Rep. 2020;21:e48317 pubmed 出版商

Bousquet Mur E, Bernardo S, Papon L, Mancini M, Fabbrizio E, Goussard M, et al. Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma. J Clin Invest. 2020;130:612-624 pubmed 出版商

Ishii Y, Taguchi A, Kukimoto I. The homeobox transcription factor HOXC13 upregulates human papillomavirus E1 gene expression and contributes to viral genome maintenance. FEBS Lett. 2020;594:751-762 pubmed 出版商

Ryszawy D, Pudełek M, Kochanowski P, Janik Olchawa N, Bogusz J, Rąpała M, et al. High bisphenol A concentrations augment the invasiveness of tumor cells through Snail-1/Cx43/ERRγ-dependent epithelial-mesenchymal transition. Toxicol In Vitro. 2020;62:104676 pubmed 出版商

Baby N, Alagappan N, Dheen S, Sajikumar S. MicroRNA-134-5p inhibition rescues long-term plasticity and synaptic tagging/capture in an Aβ(1-42)-induced model of Alzheimer's disease. Aging Cell. 2020;19:e13046 pubmed 出版商

Rein B, Yan Z, Wang Z. Diminished social interaction incentive contributes to social deficits in mouse models of autism spectrum disorder. Genes Brain Behav. 2020;19:e12610 pubmed 出版商

Palencia Campos A, Martínez Fernández M, Altunoglu U, Soto Bielicka P, Torres A, Marín P, et al. Heterozygous pathogenic variants in GLI1 are a common finding in isolated postaxial polydactyly A/B. Hum Mutat. 2020;41:265-276 pubmed 出版商

Odeh M, Tamir Livne Y, Haas T, Bengal E. P38α MAPK coordinates the activities of several metabolic pathways that together induce atrophy of denervated muscles. FEBS J. 2020;287:73-93 pubmed 出版商

Cebrià Costa J, Pascual Reguant L, Gonzalez Perez A, Serra Bardenys G, Querol J, Cosín M, et al. LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells. Oncogene. 2020;39:79-121 pubmed 出版商

Feng Q, Luo Y, Zhang X, Yang X, Hong X, Sun D, et al. MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration. Autophagy. 2020;16:641-658 pubmed 出版商

Varga J, Dér N, Zsindely N, Bodai L. Green tea infusion alleviates neurodegeneration induced by mutant Huntingtin in Drosophila. Nutr Neurosci. 2020;23:183-189 pubmed 出版商

Pepin M, Koentges C, Pfeil K, Gollmer J, Kersting S, Wiese S, et al. Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1. Front Endocrinol (Lausanne). 2019;10:872 pubmed 出版商

Schaub T, Gürgen D, Maus D, Lange C, Tarabykin V, Dragun D, et al. mTORC1 and mTORC2 Differentially Regulate Cell Fate Programs to Coordinate Osteoblastic Differentiation in Mesenchymal Stromal Cells. Sci Rep. 2019;9:20071 pubmed 出版商

Lorenzon I, Pellarin I, Pellizzari I, D Andrea S, Belletti B, Sonego M, et al. Identification and Characterization of a New Platinum-Induced TP53 Mutation in MDAH Ovarian Cancer Cells. Cells. 2019;9: pubmed 出版商

Schmeisser S, Li S, Bouchard B, Ruiz M, Des Rosiers C, Roy R. Muscle-Specific Lipid Hydrolysis Prolongs Lifespan through Global Lipidomic Remodeling. Cell Rep. 2019;29:4540-4552.e8 pubmed 出版商

Lee H, Lee K, Chen C, Lee T. Genetic deletion of soluble epoxide hydrolase delays the progression of Alzheimer's disease. J Neuroinflammation. 2019;16:267 pubmed 出版商

Lee D, Hokinson D, Park S, Elvira R, Kusuma F, Lee J, et al. ER Stress Induces Cell Cycle Arrest at the G2/M Phase Through eIF2α Phosphorylation and GADD45α. Int J Mol Sci. 2019;20: pubmed 出版商

Park S, Kang N, Song E, Wie M, Lee E, Hwang S, et al. ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress. Nat Commun. 2019;10:5718 pubmed 出版商

Jonker C, Deo C, Zager P, Tkachuk A, Weinstein A, Rodriguez Boulan E, et al. Accurate measurement of fast endocytic recycling kinetics in real time. J Cell Sci. 2019;: pubmed 出版商

Hussain S, Bedekovics T, Ali A, Zaid O, May D, Roux K, et al. A cysteine near the C-terminus of UCH-L1 is dispensable for catalytic activity but is required to promote AKT phosphorylation, eIF4F assembly, and malignant B-cell survival. Cell Death Discov. 2019;5:152 pubmed 出版商

Young R, Ewan K, Ferrer V, Allende M, Godovac Zimmermann J, Dale T, et al. Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation. elife. 2019;8: pubmed 出版商

Casanova M, Moscatelli M, Chauvière L, Huret C, Samson J, Liyakat Ali T, et al. A primate-specific retroviral enhancer wires the XACT lncRNA into the core pluripotency network in humans. Nat Commun. 2019;10:5652 pubmed 出版商

Kouloulia S, Hallin E, Simbriger K, Amorim I, Lach G, Amvrosiadis T, et al. Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity. Cell Rep. 2019;29:3620-3635.e7 pubmed 出版商

Sabatino M, Castellaro A, Racca A, Carbajosa González S, Pansa M, Soria G, et al. Krüppel-Like Factor 6 Is Required for Oxidative and Oncogene-Induced Cellular Senescence. Front Cell Dev Biol. 2019;7:297 pubmed 出版商

Ferron M, Cadiet J, Persello A, Prat V, Denis M, Erraud A, et al. O-GlcNAc stimulation: A new metabolic approach to treat septic shock. Sci Rep. 2019;9:18751 pubmed 出版商

Napoli B, Gumeni S, Forgiarini A, Fantin M, De Filippis C, Panzeri E, et al. Naringenin Ameliorates Drosophila ReepA Hereditary Spastic Paraplegia-Linked Phenotypes. Front Neurosci. 2019;13:1202 pubmed 出版商

Pancholi S, Leal M, Ribas R, Simigdala N, Schuster E, Chateau Joubert S, et al. Combination of mTORC1/2 inhibitor vistusertib plus fulvestrant in vitro and in vivo targets oestrogen receptor-positive endocrine-resistant breast cancer. Breast Cancer Res. 2019;21:135 pubmed 出版商

Schäfer I, Kaisler J, Scheller A, Kirchhoff F, Haghikia A, Faissner A. Conditional Deletion of LRP1 Leads to Progressive Loss of Recombined NG2-Expressing Oligodendrocyte Precursor Cells in a Novel Mouse Model. Cells. 2019;8: pubmed 出版商

Bosseboeuf A, Baron A, Duval E, Gautier A, Sourdaine P, Auvray P. K092A and K092B, Two Peptides Isolated from the Dogfish (Scyliorhinus canicula L.), with Potential Antineoplastic Activity Against Human Prostate and Breast Cancer Cells. Mar Drugs. 2019;17: pubmed 出版商

Delviks Frankenberry K, Ackerman D, Timberlake N, Hamscher M, Nikolaitchik O, HU W, et al. Development of Lentiviral Vectors for HIV-1 Gene Therapy with Vif-Resistant APOBEC3G. Mol Ther Nucleic Acids. 2019;18:1023-1038 pubmed 出版商

Albig C, Wang C, Dann G, Wojcik F, Schauer T, Krause S, et al. JASPer controls interphase histone H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila. Nat Commun. 2019;10:5343 pubmed 出版商

Piriya Ananda Babu L, Wang H, Eguchi K, Guillaud L, Takahashi T. Microtubule and Actin Differentially Regulate Synaptic Vesicle Cycling to Maintain High-frequency Neurotransmission. J Neurosci. 2019;: pubmed 出版商

Ferrari R, de Llobet Cucalon L, Di Vona C, Le Dilly F, Vidal E, Lioutas A, et al. TFIIIC Binding to Alu Elements Controls Gene Expression via Chromatin Looping and Histone Acetylation. Mol Cell. 2019;: pubmed 出版商

Cisse O, Quraishi M, Gulluni F, Guffanti F, Mavrommati I, Suthanthirakumaran M, et al. Downregulation of class II phosphoinositide 3-kinase PI3K-C2β delays cell division and potentiates the effect of docetaxel on cancer cell growth. J Exp Clin Cancer Res. 2019;38:472 pubmed 出版商

Hwang J, Seo J, Beshiri M, Wankowicz S, Liu D, Cheung A, et al. CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer. Cell Rep. 2019;29:2355-2370.e6 pubmed 出版商

Ljepoja B, Schreiber C, Gegenfurtner F, García Román J, Köhler B, Zahler S, et al. Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A. PLoS ONE. 2019;14:e0224314 pubmed 出版商

Madhukar N, Khade P, Huang L, Gayvert K, Galletti G, Stogniew M, et al. A Bayesian machine learning approach for drug target identification using diverse data types. Nat Commun. 2019;10:5221 pubmed 出版商

Zurlo G, Liu X, Takada M, Fan C, Simon J, Ptacek T, et al. Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer. Nat Commun. 2019;10:5177 pubmed 出版商

Montero J, Gstalder C, Kim D, Sadowicz D, Miles W, Manos M, et al. Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies. Nat Commun. 2019;10:5157 pubmed 出版商

Nagati J, Xu M, Garcia T, Comerford S, Hammer R, Garcia J. A substitution mutation in a conserved domain of mammalian acetate-dependent acetyl CoA synthetase 2 results in destabilized protein and impaired HIF-2 signaling. PLoS ONE. 2019;14:e0225105 pubmed 出版商

Huang Q, Chan K, Tobey I, Chan Y, Poterba T, Boutros C, et al. Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids. PLoS ONE. 2019;14:e0225206 pubmed 出版商

Hua R, Wei H, Liu C, Zhang Y, Liu S, Guo Y, et al. FBXO47 regulates telomere-inner nuclear envelope integration by stabilizing TRF2 during meiosis. Nucleic Acids Res. 2019;47:11755-11770 pubmed 出版商

Murányi J, Varga A, Gyulavári P, Pénzes K, Németh C, Csala M, et al. Novel Crizotinib-GnRH Conjugates Revealed the Significance of Lysosomal Trapping in GnRH-Based Drug Delivery Systems. Int J Mol Sci. 2019;20: pubmed 出版商

Marcozzi S, Rossi V, Salvatore G, Di Rella F, De Felici M, Klinger F. Distinct effects of epirubicin, cisplatin and cyclophosphamide on ovarian somatic cells of prepuberal ovaries. Aging (Albany NY). 2019;11:10532-10556 pubmed 出版商

Millen S, Gross C, Donhauser N, Mann M, Peloponese J, Thoma Kress A. Collagen IV (COL4A1, COL4A2), a Component of the Viral Biofilm, Is Induced by the HTLV-1 Oncoprotein Tax and Impacts Virus Transmission. Front Microbiol. 2019;10:2439 pubmed 出版商

Hatanaka Y, Kawasaki T, Abe T, Shioi G, Kohno T, Hattori M, et al. Semaphorin 6A-Plexin A2/A4 Interactions with Radial Glia Regulate Migration Termination of Superficial Layer Cortical Neurons. iScience. 2019;21:359-374 pubmed 出版商

Baron O, Grieshober D, Dias C, Fanto M. Fat cadherins in mouse models of degenerative ataxias. Sci Rep. 2019;9:16155 pubmed 出版商

Abaffy P, Tomankova S, Naraine R, Kubista M, Sindelka R. The role of nitric oxide during embryonic wound healing. BMC Genomics. 2019;20:815 pubmed 出版商

Osada A, Endo K, Kimura Y, Sakamoto K, Nakamura R, Sakamoto K, et al. Addiction of mesenchymal phenotypes on the FGF/FGFR axis in oral squamous cell carcinoma cells. PLoS ONE. 2019;14:e0217451 pubmed 出版商

Miah S, Banks C, Ogunbolude Y, Bagu E, Berg J, Saraf A, et al. BRK phosphorylates SMAD4 for proteasomal degradation and inhibits tumor suppressor FRK to control SNAIL, SLUG, and metastatic potential. Sci Adv. 2019;5:eaaw3113 pubmed 出版商

Dudka D, Castrogiovanni C, Liaudet N, Vassal H, Meraldi P. Spindle-Length-Dependent HURP Localization Allows Centrosomes to Control Kinetochore-Fiber Plus-End Dynamics. Curr Biol. 2019;29:3563-3578.e6 pubmed 出版商

Bott A, Shen J, Tonelli C, Zhan L, Sivaram N, Jiang Y, et al. Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism. Cell Rep. 2019;29:1287-1298.e6 pubmed 出版商

Sommer A, Falcenberg M, Ljepoja B, Frohlich T, Arnold G, Wagner E, et al. Downregulation of GRK5 hampers the migration of breast cancer cells. Sci Rep. 2019;9:15548 pubmed 出版商

Laforet P, Inoue M, Goillot E, Lefeuvre C, Cagin U, Streichenberger N, et al. Deep morphological analysis of muscle biopsies from type III glycogenesis (GSDIII), debranching enzyme deficiency, revealed stereotyped vacuolar myopathy and autophagy impairment. Acta Neuropathol Commun. 2019;7:167 pubmed 出版商

Jiang J, Srivastava S, Seim G, Pavlova N, King B, Zou L, et al. Promoter demethylation of the asparagine synthetase gene is required for ATF4-dependent adaptation to asparagine depletion. J Biol Chem. 2019;294:18674-18684 pubmed 出版商

Zhou D, Fu H, Han Y, Zhang L, Liu S, Lin L, et al. Sonic hedgehog connects podocyte injury to mesangial activation and glomerulosclerosis. JCI Insight. 2019;4: pubmed 出版商

Wang C, Su M, Cheng H, Kuo P, Tsai P. Fetuin-A Inhibits Placental Cell Growth and Ciliogenesis in Gestational Diabetes Mellitus. Int J Mol Sci. 2019;20: pubmed 出版商

Srikantan S, Deng Y, Cheng Z, Luo A, Qin Y, Gao Q, et al. The tumor suppressor TMEM127 regulates insulin sensitivity in a tissue-specific manner. Nat Commun. 2019;10:4720 pubmed 出版商

Bosseboeuf A, Baron A, Duval E, Gautier A, Sourdaine P, Auvray P. A Potential Antineoplastic Peptide of Human Prostate Cancer Cells Derived from the Lesser Spotted Dogfish (Scyliorhinus canicula L.). Mar Drugs. 2019;17: pubmed 出版商

Kumari A, Srivastava S, Manne R, Sisodiya S, Santra M, Guchhait S, et al. C12, a combretastatin-A4 analog, exerts anticancer activity by targeting microtubules. Biochem Pharmacol. 2019;170:113663 pubmed 出版商

Leon Aparicio D, Salvador C, Aparicio Trejo O, Briones Herrera A, Pedraza Chaverri J, Vaca L, et al. Novel Potassium Channels in Kidney Mitochondria: The Hyperpolarization-Activated and Cyclic Nucleotide-Gated HCN Channels. Int J Mol Sci. 2019;20: pubmed 出版商

Eshelman M, Matthews S, Schleicher E, Fleeman R, Kawasawa Y, Stumpo D, et al. Tristetraprolin targets Nos2 expression in the colonic epithelium. Sci Rep. 2019;9:14413 pubmed 出版商

Moss Taylor L, Upadhyay A, Pan X, Kim M, O Connor M. Body Size and Tissue-Scaling Is Regulated by Motoneuron-Derived Activinß in Drosophila melanogaster. Genetics. 2019;213:1447-1464 pubmed 出版商

Mousavi S, Skjeldal F, Fønhus M, Haugen L, Eskild W, Berg T, et al. Receptor-Mediated Endocytosis of VEGF-A in Rat Liver Sinusoidal Endothelial Cells. Biomed Res Int. 2019;2019:5496197 pubmed 出版商

Sarraf S, Sideris D, Giagtzoglou N, Ni L, Kankel M, Sen A, et al. PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. Cell Rep. 2019;29:225-235.e5 pubmed 出版商

Azzi Martin L, He W, Péré Védrenne C, Korolik V, Alix C, Prochazkova Carlotti M, et al. Cytolethal distending toxin induces the formation of transient messenger-rich ribonucleoprotein nuclear invaginations in surviving cells. PLoS Pathog. 2019;15:e1007921 pubmed 出版商

Codony Servat J, Viteri S, Codony Servat C, Ito M, Bracht J, Berenguer J, et al. Hsp90 inhibitors enhance the antitumoral effect of osimertinib in parental and osimertinib-resistant non-small cell lung cancer cell lines. Transl Lung Cancer Res. 2019;8:340-351 pubmed 出版商

Pauleau A, Bergner A, Kajtez J, Erhardt S. The checkpoint protein Zw10 connects CAL1-dependent CENP-A centromeric loading and mitosis duration in Drosophila cells. PLoS Genet. 2019;15:e1008380 pubmed 出版商

Lucà R, di Blasio G, Gallo D, Monteleone V, Manni I, Fici L, et al. Estrogens Counteract Platinum-Chemosensitivity by Modifying the Subcellular Localization of MDM4. Cancers (Basel). 2019;11: pubmed 出版商

Keller B, Maier J, Weldle M, Segan S, Traenkle B, Rothbauer U. A Strategy to Optimize the Generation of Stable Chromobody Cell Lines for Visualization and Quantification of Endogenous Proteins in Living Cells. Antibodies (Basel). 2019;8: pubmed 出版商

He J, Wink S, de Bont H, Le Dévédec S, Zhang Y, van de Water B. FRET biosensor-based kinase inhibitor screen for ERK and AKT activity reveals differential kinase dependencies for proliferation in TNBC cells. Biochem Pharmacol. 2019;169:113640 pubmed 出版商

van der Noord V, McLaughlin R, Smid M, Foekens J, Martens J, Zhang Y, et al. An increased cell cycle gene network determines MEK and Akt inhibitor double resistance in triple-negative breast cancer. Sci Rep. 2019;9:13308 pubmed 出版商

Asai Y, Fukuchi K, Tanno Y, Koitabashi Kiyozuka S, Kiyozuka T, Noda Y, et al. Aurora B kinase activity is regulated by SET/TAF1 on Sgo2 at the inner centromere. J Cell Biol. 2019;218:3223-3236 pubmed 出版商

Campbell S, Amin M, Varma D, Bidone T. Computational model demonstrates that Ndc80-associated proteins strengthen kinetochore-microtubule attachments in metaphase. Cytoskeleton (Hoboken). 2019;76:549-561 pubmed 出版商

Zhou H, Zheng T, Wang T, Li Q, Wang F, Liang X, et al. CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment. BMC Biol. 2019;17:73 pubmed 出版商

Franchini L, Stanic J, Ponzoni L, Mellone M, Carrano N, Musardo S, et al. Linking NMDA Receptor Synaptic Retention to Synaptic Plasticity and Cognition. iScience. 2019;19:927-939 pubmed 出版商

Vardhana S, Arnold P, Rosen B, Chen Y, Carey B, Huangfu D, et al. Glutamine independence is a selectable feature of pluripotent stem cells. Nat Metab. 2019;1:676-687 pubmed 出版商

Spracklen A, Lamb M, Groen C, Tootle T. Pharmaco-Genetic Screen To Uncover Actin Regulators Targeted by Prostaglandins During Drosophila Oogenesis. G3 (Bethesda). 2019;9:3555-3565 pubmed 出版商

Olah J, Szunyogh S, Szénási T, Szaniszlo T, Szabó A, Lehotzky A, et al. Interactions between two regulatory proteins of microtubule dynamics, HDAC6, TPPP/p25, and the hub protein, DYNLL/LC8. Biochim Biophys Acta Mol Cell Res. 2019;1866:118556 pubmed 出版商

Zhao W, Cao L, Ying H, Zhang W, Li D, Zhu X, et al. Endothelial CDS2 deficiency causes VEGFA-mediated vascular regression and tumor inhibition. Cell Res. 2019;29:895-910 pubmed 出版商

Steinparzer I, Sedlyarov V, Rubin J, Eislmayr K, Galbraith M, Levandowski C, et al. Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions. Mol Cell. 2019;76:485-499.e8 pubmed 出版商

Grudina C, Kouroupi G, Nonaka T, Hasegawa M, Matsas R, Zurzolo C. Human NPCs can degrade α-syn fibrils and transfer them preferentially in a cell contact-dependent manner possibly through TNT-like structures. Neurobiol Dis. 2019;132:104609 pubmed 出版商

Walker R, Keynton J, Grimes D, Sreekumar V, Williams D, Esapa C, et al. Ciliary exclusion of Polycystin-2 promotes kidney cystogenesis in an autosomal dominant polycystic kidney disease model. Nat Commun. 2019;10:4072 pubmed 出版商

Pan D, Walstein K, Take A, Bier D, Kaiser N, Musacchio A. Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing. Nat Commun. 2019;10:4046 pubmed 出版商

Greenberg R, Long H, Swigut T, Wysocka J. Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome. Cell. 2019;178:1421-1436.e24 pubmed 出版商

Roesler M, Lombino F, Freitag S, Schweizer M, Hermans Borgmeyer I, Schwarz J, et al. Myosin XVI Regulates Actin Cytoskeleton Dynamics in Dendritic Spines of Purkinje Cells and Affects Presynaptic Organization. Front Cell Neurosci. 2019;13:330 pubmed 出版商

Schneeberger P, Bierhals T, Neu A, Hempel M, Kutsche K. de novo MEPCE nonsense variant associated with a neurodevelopmental disorder causes disintegration of 7SK snRNP and enhanced RNA polymerase II activation. Sci Rep. 2019;9:12516 pubmed 出版商

Niu J, Sun Y, Chen B, Zheng B, Jarugumilli G, Walker S, et al. Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation through S-palmitoylation. Nature. 2019;573:139-143 pubmed 出版商

Rouillon C, Depince A, Chenais N, Le Bail P, Labbe C. Somatic cell nuclear transfer in non-enucleated goldfish oocytes: understanding DNA fate during oocyte activation and first cellular division. Sci Rep. 2019;9:12462 pubmed 出版商

Ganesan S, Roy C. Host cell depletion of tryptophan by IFNγ-induced Indoleamine 2,3-dioxygenase 1 (IDO1) inhibits lysosomal replication of Coxiella burnetii. PLoS Pathog. 2019;15:e1007955 pubmed 出版商

Rathod M, Chatterjee S, Dutta S, Kalraiya R, Bhattacharyya D, De A. Mannose glycosylation is an integral step for NIS localization and function in human breast cancer cells. J Cell Sci. 2019;132: pubmed 出版商

Sheng X, Li Y, Li Y, Liu W, Lu Z, Zhan J, et al. PLOD2 contributes to drug resistance in laryngeal cancer by promoting cancer stem cell-like characteristics. BMC Cancer. 2019;19:840 pubmed 出版商

Schipper K, Seinstra D, Paulien Drenth A, van der Burg E, Ramovs V, Sonnenberg A, et al. Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin. Nat Commun. 2019;10:3800 pubmed 出版商

Miller C, Wells R, McKenzie N, Trick M, Ball J, Fatihi A, et al. Variation in Expression of the HECT E3 Ligase UPL3 Modulates LEC2 Levels, Seed Size, and Crop Yields in Brassica napus. Plant Cell. 2019;31:2370-2385 pubmed 出版商

Gómez H L, Felipe Medina N, Condezo Y, García Valiente R, Ramos I, Suja J, et al. The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility. PLoS Genet. 2019;15:e1008316 pubmed 出版商

Pinto C, Khandekar A, Bhavna R, Kiesel P, Pigino G, Sonawane M. Microridges are apical epithelial projections formed of F-actin networks that organize the glycan layer. Sci Rep. 2019;9:12191 pubmed 出版商

Guo L, Mohd K, Ren H, Xin G, Jiang Q, Clarke P, et al. Phosphorylation of importin-α1 by CDK1-cyclin B1 controls mitotic spindle assembly. J Cell Sci. 2019;132: pubmed 出版商

Kim J, Wojcik M, Wang Y, Moon S, Zin E, Marnani N, et al. Oblique-plane single-molecule localization microscopy for tissues and small intact animals. Nat Methods. 2019;16:853-857 pubmed 出版商

Swartz S, McKay L, Su K, Bury L, Padeganeh A, Maddox P, et al. Quiescent Cells Actively Replenish CENP-A Nucleosomes to Maintain Centromere Identity and Proliferative Potential. Dev Cell. 2019;51:35-48.e7 pubmed 出版商

Ranjan P, Awasthi M, Snell W. Transient Internalization and Microtubule-Dependent Trafficking of a Ciliary Signaling Receptor from the Plasma Membrane to the Cilium. Curr Biol. 2019;29:2942-2947.e2 pubmed 出版商

Fung T, Ji W, Higgs H, Chakrabarti R. Two distinct actin filament populations have effects on mitochondria, with differences in stimuli and assembly factors. J Cell Sci. 2019;132: pubmed 出版商

Zhuo H, Zhou D, Wang Y, Mo H, Yu Y, Liu Y. Sonic hedgehog selectively promotes lymphangiogenesis after kidney injury through noncanonical pathway. Am J Physiol Renal Physiol. 2019;317:F1022-F1033 pubmed 出版商

Xiao L, Chen Y, Yuan Y, Xu B, Gao Q, Chen P, et al. PC-1 NF suppresses high glucose-stimulated inflammation and extracellular matrix accumulation in glomerular mesangial cells via the Wnt/β-catenin signaling. Exp Ther Med. 2019;18:2029-2036 pubmed 出版商

Zeeshan M, Ferguson D, Abel S, Burrrell A, Rea E, Brady D, et al. Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission. Life Sci Alliance. 2019;2: pubmed 出版商

Gąsiorowski L, Furu A, Hejnol A. Morphology of the nervous system of monogonont rotifer Epiphanes senta with a focus on sexual dimorphism between feeding females and dwarf males. Front Zool. 2019;16:33 pubmed 出版商

Hoppstädter J, Dembek A, Linnenberger R, Dahlem C, Barghash A, Fecher Trost C, et al. Toll-Like Receptor 2 Release by Macrophages: An Anti-inflammatory Program Induced by Glucocorticoids and Lipopolysaccharide. Front Immunol. 2019;10:1634 pubmed 出版商

Lauzier A, Normandeau Guimond J, Vaillancourt Lavigueur V, Boivin V, Charbonneau M, Rivard N, et al. Colorectal cancer cells respond differentially to autophagy inhibition in vivo. Sci Rep. 2019;9:11316 pubmed 出版商

Nader K, Krysiak A, Beroun A, Pekala M, Szymanska M, Kuzniewska B, et al. Loss of serum response factor in mature neurons in the dentate gyrus alters the morphology of dendritic spines and hippocampus-dependent behavioral tasks. Brain Struct Funct. 2019;224:2691-2701 pubmed 出版商

Bloodgood R, Tetreault J, Sloboda R. The Chlamydomonas flagellar membrane glycoprotein FMG-1B is necessary for expression of force at the flagellar surface. J Cell Sci. 2019;132: pubmed 出版商

Yeoh L, Goodman C, Mollard V, McHugh E, Lee V, Sturm A, et al. Alternative splicing is required for stage differentiation in malaria parasites. Genome Biol. 2019;20:151 pubmed 出版商

Marrugal A, Ferrer I, Pastor M, Ojeda L, Quintanal Villalonga Á, Carnero A, et al. Impact of Heat Shock Protein 90 Inhibition on the Proteomic Profile of Lung Adenocarcinoma as Measured by Two-Dimensional Electrophoresis Coupled with Mass Spectrometry. Cells. 2019;8: pubmed 出版商

Cabrera E, Raninga P, Khanna K, Freire R. GSK3-β Stimulates Claspin Degradation via β-TrCP Ubiquitin Ligase and Alters Cancer Cell Survival. Cancers (Basel). 2019;11: pubmed 出版商

Quesada López T, Gavaldà Navarro A, Morón Ros S, Campderros L, Iglesias R, Giralt M, et al. GPR120 controls neonatal brown adipose tissue thermogenic induction. Am J Physiol Endocrinol Metab. 2019;317:E742-E750 pubmed 出版商

Logsdon G, Gambogi C, Liskovykh M, Barrey E, Larionov V, Miga K, et al. Human Artificial Chromosomes that Bypass Centromeric DNA. Cell. 2019;178:624-639.e19 pubmed 出版商

Pasquier A, Vivot K, Erbs E, Spiegelhalter C, Zhang Z, Aubert V, et al. Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes. Nat Commun. 2019;10:3312 pubmed 出版商

Tomay F, Marinelli A, Leoni V, Caccia C, Matros A, Mock H, et al. Purple corn extract induces long-lasting reprogramming and M2 phenotypic switch of adipose tissue macrophages in obese mice. J Transl Med. 2019;17:237 pubmed 出版商

McMahon K, Wu Y, Gambin Y, Sierecki E, Tillu V, HALL T, et al. Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis. Nat Commun. 2019;10:3279 pubmed 出版商

Kazakevych J, Stoyanova E, Liebert A, Varga Weisz P. Transcriptome analysis identifies a robust gene expression program in the mouse intestinal epithelium on aging. Sci Rep. 2019;9:10410 pubmed 出版商

Kumar A, Shutova M, Tanaka K, Iwamoto D, Calderwood D, Svitkina T, et al. Filamin A mediates isotropic distribution of applied force across the actin network. J Cell Biol. 2019;218:2481-2491 pubmed 出版商

Olbrich T, Vega Sendino M, Murga M, de Carcer G, Malumbres M, Ortega S, et al. A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells. Cell Rep. 2019;28:597-604.e4 pubmed 出版商

Wood K, Rowlands C, Qureshi W, Thomas H, Buczek W, Briggs T, et al. Disease modeling of core pre-mRNA splicing factor haploinsufficiency. Hum Mol Genet. 2019;28:3704-3723 pubmed 出版商

Runwal G, Stamatakou E, Siddiqi F, Puri C, Zhu Y, Rubinsztein D. LC3-positive structures are prominent in autophagy-deficient cells. Sci Rep. 2019;9:10147 pubmed 出版商

Wang S, Lin H, Chen Y, Hsu T, Chuang J, Kao T, et al. CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation. J Neuroinflammation. 2019;16:146 pubmed 出版商

Zierhut C, Yamaguchi N, Paredes M, Luo J, Carroll T, Funabiki H. The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death. Cell. 2019;178:302-315.e23 pubmed 出版商

Mandati V, Del Maestro L, Dingli F, Lombard B, Loew D, Molinie N, et al. Phosphorylation of Merlin by Aurora A kinase appears necessary for mitotic progression. J Biol Chem. 2019;294:12992-13005 pubmed 出版商

Kute P, Ramakrishna S, Neelagandan N, Chattarji S, Muddashetty R. NMDAR mediated translation at the synapse is regulated by MOV10 and FMRP. Mol Brain. 2019;12:65 pubmed 出版商

Nogueira Recalde U, Lorenzo Gómez I, Blanco F, Loza M, Grassi D, Shirinsky V, et al. Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy. EBioMedicine. 2019;45:588-605 pubmed 出版商

Koedoot E, Fokkelman M, Rogkoti V, Smid M, van de Sandt I, de Bont H, et al. Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes. Nat Commun. 2019;10:2983 pubmed 出版商

Van Haute L, Lee S, McCann B, Powell C, Bansal D, Vasiliauskaite L, et al. NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs. Nucleic Acids Res. 2019;47:8720-8733 pubmed 出版商

Lee M, Hwang Y, Yoon J, Sun J, Harned A, Nagashima K, et al. Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled. J Cell Biol. 2019;: pubmed 出版商

Wagner W, Lippmann K, Heisler F, Gromova K, Lombino F, Roesler M, et al. Myosin VI Drives Clathrin-Mediated AMPA Receptor Endocytosis to Facilitate Cerebellar Long-Term Depression. Cell Rep. 2019;28:11-20.e9 pubmed 出版商

Zhang Y, Du X, Liu M, Tang F, Zhang P, Ai C, et al. Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy. Cell Res. 2019;29:609-627 pubmed 出版商

Platanitis E, Demiröz D, Schneller A, Fischer K, Capelle C, Hartl M, et al. A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription. Nat Commun. 2019;10:2921 pubmed 出版商

McLaughlin R, He J, van der Noord V, Redel J, Foekens J, Martens J, et al. A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy. Breast Cancer Res. 2019;21:77 pubmed 出版商

Chiticariu E, Regamey A, Huber M, Hohl D. CENPV is a CYLD-interacting molecule regulating ciliary acetylated α-tubulin. J Invest Dermatol. 2019;: pubmed 出版商

Brkić Z, Milosavljevic M, Glavonic E, Adzic M. Mitochondrial signaling in inflammation-induced depressive behavior in female and male rats: The role of glucocorticoid receptor. Brain Res Bull. 2019;150:317-327 pubmed 出版商

Manning C, Biga V, Boyd J, Kursawe J, Ymisson B, Spiller D, et al. Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis. Nat Commun. 2019;10:2835 pubmed 出版商

Rageot D, Bohnacker T, Keles E, McPhail J, Hoffmann R, Melone A, et al. (S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine (PQR530), a Potent, Orally Bioavailable, and Brain-Penetrable Dual Inhibitor of Class I PI3K and mTOR Kinase. J Med Chem. 2019;62:6241-6261 pubmed 出版商

Tettey T, Gao X, Shao W, Li H, Story B, Chitsazan A, et al. A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing. Cell Rep. 2019;27:3770-3779.e7 pubmed 出版商

Feldmann L, Le Prieult F, Felzen V, Thal S, Engelhard K, Behl C, et al. Proteasome and Autophagy-Mediated Impairment of Late Long-Term Potentiation (l-LTP) after Traumatic Brain Injury in the Somatosensory Cortex of Mice. Int J Mol Sci. 2019;20: pubmed 出版商

Najafov A, Mookhtiar A, Luu H, Ordureau A, Pan H, Amin P, et al. TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL. Mol Cell. 2019;: pubmed 出版商

Li J, Ma C, Long F, Yang D, Liu X, Hu Y, et al. Parkin Impairs Antiviral Immunity by Suppressing the Mitochondrial Reactive Oxygen Species-Nlrp3 Axis and Antiviral Inflammation. iScience. 2019;16:468-484 pubmed 出版商

Martín Cortázar C, Chiodo Y, Jiménez P R, Bernabé M, Cayuela M, Iglesias T, et al. CDCA7 finely tunes cytoskeleton dynamics to promote lymphoma migration and invasion. Haematologica. 2019;: pubmed 出版商

Li G, Wang M, Ren L, Li H, Liu Q, Ouyang Y, et al. Regulator of G protein signaling 20 promotes proliferation and migration in bladder cancer via NF-κB signaling. Biomed Pharmacother. 2019;117:109112 pubmed 出版商

Piacentini L, Marchetti M, Bucciarelli E, Casale A, Cappucci U, Bonifazi P, et al. A role of the Trx-G complex in Cid/CENP-A deposition at Drosophila melanogaster centromeres. Chromosoma. 2019;: pubmed 出版商

Dankner M, Ouellet V, Communal L, Schmitt E, Perkins D, Annis M, et al. CCN3/Nephroblastoma Overexpressed Is a Functional Mediator of Prostate Cancer Bone Metastasis That Is Associated with Poor Patient Prognosis. Am J Pathol. 2019;189:1451-1461 pubmed 出版商

Morii K, Yamasaki S, Doi S, Irifuku T, Sasaki K, Doi T, et al. microRNA-200c regulates KLOTHO expression in human kidney cells under oxidative stress. PLoS ONE. 2019;14:e0218468 pubmed 出版商

Zhu L, Liao S, Fukunaga R. Drosophila Regnase-1 RNase is required for mRNA and miRNA profile remodelling during larva-to-adult metamorphosis. RNA Biol. 2019;16:1386-1400 pubmed 出版商

Alcala S, Martinelli P, Hermann P, Heeschen C, Sainz B. The Anthrax Toxin Receptor 1 (ANTXR1) Is Enriched in Pancreatic Cancer Stem Cells Derived from Primary Tumor Cultures. Stem Cells Int. 2019;2019:1378639 pubmed 出版商

Singh P, Roukounakis A, Weber A, Das K, Sohm B, Villunger A, et al. Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim. Cell Death Differ. 2019;: pubmed 出版商

Trapp Fragnet L, Courvoisier K, Remy S, Pape G, Loustalot F, Denesvre C. Identification of Marek's Disease Virus VP22 Tegument Protein Domains Essential for Virus Cell-to-Cell Spread, Nuclear Localization, Histone Association and Cell-Cycle Arrest. Viruses. 2019;11: pubmed 出版商

Alfano D, Altomonte A, Cortes C, Bilio M, Kelly R, Baldini A. Tbx1 regulates extracellular matrix-cell interactions in the second heart field. Hum Mol Genet. 2019;28:2295-2308 pubmed 出版商

Li G, Jin D, Zhong T. Tubgcp3 Is Required for Retinal Progenitor Cell Proliferation During Zebrafish Development. Front Mol Neurosci. 2019;12:126 pubmed 出版商

Good A, Haemmerle M, Oguh A, Doliba N, Stoffers D. Metabolic stress activates an ERK/hnRNPK/DDX3X pathway in pancreatic β cells. Mol Metab. 2019;: pubmed 出版商

Whitfield M, Thomas L, Bequignon E, Schmitt A, Stouvenel L, Montantin G, et al. Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia. Am J Hum Genet. 2019;: pubmed 出版商

Kono K, Yoshiura S, Fujita I, Okada Y, Shitamukai A, Shibata T, et al. Reconstruction of Par-dependent polarity in apolar cells reveals a dynamic process of cortical polarization. elife. 2019;8: pubmed 出版商

Magre I, Fandade V, Damle I, Banerjee P, Yadav S, Sonawane M, et al. Nup358 regulates microridge length by controlling SUMOylation-dependent activity of aPKC in zebrafish epidermis. J Cell Sci. 2019;132: pubmed 出版商

Liu Y, Sugiura Y, Sudhof T, Lin W. Ablation of all synaptobrevin vSNAREs blocks evoked but not spontaneous neurotransmitter release at neuromuscular synapses. J Neurosci. 2019;: pubmed 出版商

Hambleton E, Jones V, Maegele I, Kvaskoff D, Sachsenheimer T, Guse A. Sterol transfer by atypical cholesterol-binding NPC2 proteins in coral-algal symbiosis. elife. 2019;8: pubmed 出版商

Wang C, Ma S, Bi S, Su L, Huang S, Miao J, et al. Enhancing autophagy protects platelets in immune thrombocytopenia patients. Ann Transl Med. 2019;7:134 pubmed 出版商

Bauer C, Schneeberger P, Kortüm F, Altmuller J, Santos Simarro F, Baker L, et al. Gain-of-Function Mutations in KCNN3 Encoding the Small-Conductance Ca2+-Activated K+ Channel SK3 Cause Zimmermann-Laband Syndrome. Am J Hum Genet. 2019;104:1139-1157 pubmed 出版商

Liu X, Wang M, Jiang T, He J, Fu X, Xu Y. IDO1 Maintains Pluripotency of Primed Human Embryonic Stem Cells by Promoting Glycolysis. Stem Cells. 2019;: pubmed 出版商

Luo Y, Barrios Rodiles M, Gupta G, Zhang Y, Ogunjimi A, Bashkurov M, et al. Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility. Nat Commun. 2019;10:2356 pubmed 出版商

Lin S, Liu Y. Mechanical Stretch Induces mTOR Recruitment and Activation at the Phosphatidic Acid-Enriched Macropinosome in Muscle Cell. Front Cell Dev Biol. 2019;7:78 pubmed 出版商

Napolioni V, Pariano M, Borghi M, Oikonomou V, Galosi C, De Luca A, et al. Genetic Polymorphisms Affecting IDO1 or IDO2 Activity Differently Associate With Aspergillosis in Humans. Front Immunol. 2019;10:890 pubmed 出版商

Iwai K, Nambu T, Dairiki R, Ohori M, Yu J, Burke K, et al. Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor. Sci Adv. 2019;5:eaav3660 pubmed 出版商

Gambarotto D, Pennetier C, Ryniawec J, Buster D, Gogendeau D, Goupil A, et al. Plk4 Regulates Centriole Asymmetry and Spindle Orientation in Neural Stem Cells. Dev Cell. 2019;: pubmed 出版商

Lismont C, Koster J, Provost S, Baes M, Van Veldhoven P, Waterham H, et al. Deciphering the potential involvement of PXMP2 and PEX11B in hydrogen peroxide permeation across the peroxisomal membrane reveals a role for PEX11B in protein sorting. Biochim Biophys Acta Biomembr. 2019;: pubmed 出版商

Lichtig H, Cohen Y, Bin Nun N, Golubkov V, Frank D. PTK7 proteolytic fragment proteins function during early Xenopus development. Dev Biol. 2019;: pubmed 出版商

Hayashishita M, Kawahara H, Yokota N. BAG6 deficiency induces mis-distribution of mitochondrial clusters under depolarization. FEBS Open Bio. 2019;9:1281-1291 pubmed 出版商

Zhao Y, Zhong S, Zhang S, Bi J, Xiao Z, Wang S, et al. UBN2 promotes tumor progression via the Ras/MAPK pathway and predicts poor prognosis in colorectal cancer. Cancer Cell Int. 2019;19:126 pubmed 出版商

Fouquerel E, Barnes R, Uttam S, Watkins S, Bruchez M, Opresko P. Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis. Mol Cell. 2019;: pubmed 出版商

Reyes Fermín L, Avila Rojas S, Aparicio Trejo O, Tapia E, Rivero I, Pedraza Chaverri J. The Protective Effect of Alpha-Mangostin against Cisplatin-Induced Cell Death in LLC-PK1 Cells is Associated to Mitochondrial Function Preservation. Antioxidants (Basel). 2019;8: pubmed 出版商

Slobodnyuk K, Radic N, Ivanova S, Lladó A, Trempolec N, Zorzano A, et al. Autophagy-induced senescence is regulated by p38α signaling. Cell Death Dis. 2019;10:376 pubmed 出版商

Che L, Yang X, Ge C, El Amouri S, Wang Q, Pan D, et al. Loss of BRUCE reduces cellular energy level and induces autophagy by driving activation of the AMPK-ULK1 autophagic initiating axis. PLoS ONE. 2019;14:e0216553 pubmed 出版商

Gravotta D, Perez Bay A, Jonker C, Zager P, Benedicto I, Schreiner R, et al. Clathrin and clathrin adaptor AP-1 control apical trafficking of megalin in the biosynthetic and recycling routes. Mol Biol Cell. 2019;30:1716-1728 pubmed 出版商

Strutt H, Gamage J, Strutt D. Reciprocal action of Casein Kinase Iε on core planar polarity proteins regulates clustering and asymmetric localisation. elife. 2019;8: pubmed 出版商

Boeckel S, Hrabalkova L, Baker T, MacPherson H, Frew L, Boyle A, et al. Cathelicidins and the Onset of Labour. Sci Rep. 2019;9:7356 pubmed 出版商

Nakajima Y, Lee Z, McKinney S, Swanson S, Florens L, Gibson M. Junctional tumor suppressors interact with 14-3-3 proteins to control planar spindle alignment. J Cell Biol. 2019;218:1824-1838 pubmed 出版商

Zdankowski P, McGloin D, Swedlow J. Full volume super-resolution imaging of thick mitotic spindle using 3D AO STED microscope. Biomed Opt Express. 2019;10:1999-2009 pubmed 出版商

Giriwono P, Shirakawa H, Ohsaki Y, Sato S, Aoyama Y, Ho H, et al. Geranylgeraniol Suppresses the Expression of IRAK1 and TRAF6 to Inhibit NFκB Activation in Lipopolysaccharide-Induced Inflammatory Responses in Human Macrophage-Like Cells. Int J Mol Sci. 2019;20: pubmed 出版商

Kurolap A, Eshach Adiv O, Konnikova L, Werner L, Gonzaga Jauregui C, Steinberg M, et al. A Unique Presentation of Infantile-Onset Colitis and Eosinophilic Disease without Recurrent Infections Resulting from a Novel Homozygous CARMIL2 Variant. J Clin Immunol. 2019;39:430-439 pubmed 出版商

Xu M, Wang F, Li G, Wang X, Fang X, Jin H, et al. MED12 exerts an emerging role in actin-mediated cytokinesis via LIMK2/cofilin pathway in NSCLC. Mol Cancer. 2019;18:93 pubmed 出版商

Mazloomian A, Araki S, Ohori M, El Naggar A, Yap D, Bashashati A, et al. Pharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation. Commun Biol. 2019;2:165 pubmed 出版商

Xiao Z, Sperl B, Gartner S, Nedelko T, Stacher Priehse E, Ullrich A, et al. Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach. Oncotarget. 2019;10:2546-2560 pubmed 出版商

Zhaojie L, Yuchen L, Miao C, Yacun C, Shayi W, Anbang H, et al. Gelsolin-like actin-capping protein has prognostic value and promotes tumorigenesis and epithelial-mesenchymal transition via the Hippo signaling pathway in human bladder cancer. Ther Adv Med Oncol. 2019;11:1758835919841235 pubmed 出版商

Hamon A, García García D, Ail D, Bitard J, Chesneau A, Dalkara D, et al. Linking YAP to Müller Glia Quiescence Exit in the Degenerative Retina. Cell Rep. 2019;27:1712-1725.e6 pubmed 出版商

Felipe Abrio B, Verdugo Sivianes E, Carnero A. c-MYB- and PGC1a-dependent metabolic switch induced by MYBBP1A loss in renal cancer. Mol Oncol. 2019;: pubmed 出版商

Vezzoli E, Caron I, Talpo F, Besusso D, Conforti P, Battaglia E, et al. Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease. J Clin Invest. 2019;130:2390-2403 pubmed 出版商

Shariati S, Domínguez A, Xie S, Wernig M, Qi L, Skotheim J. Reversible Disruption of Specific Transcription Factor-DNA Interactions Using CRISPR/Cas9. Mol Cell. 2019;74:622-633.e4 pubmed 出版商

Luo Q, Xiao Y, Alex A, Cummins T, Bhatwadekar A. The Diurnal Rhythm of Insulin Receptor Substrate-1 (IRS-1) and Kir4.1 in Diabetes: Implications for a Clock Gene Bmal1. Invest Ophthalmol Vis Sci. 2019;60:1928-1936 pubmed 出版商

Tufi R, Gleeson T, von Stockum S, Hewitt V, Lee J, Terriente Félix A, et al. Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo. Cell Rep. 2019;27:1541-1550.e5 pubmed 出版商

Lee S, Kieu C, Martin C, Han J, Chen W, Kim J, et al. NFATc3 plays an oncogenic role in oral/oropharyngeal squamous cell carcinomas by promoting cancer stemness via expression of OCT4. Oncotarget. 2019;10:2306-2319 pubmed 出版商

Goto T, Kanda K, Nishikata T. Non-centrosomal microtubule structures regulated by egg activation signaling contribute to cytoplasmic and cortical reorganization in the ascidian egg. Dev Biol. 2019;448:161-172 pubmed 出版商

Xiao C, Qiu S, Li X, Luo D, Liu G. EDTP/MTMR14: A novel target for improved survivorship to prolonged anoxia and cellular protein aggregates. Neurosci Lett. 2019;705:151-158 pubmed 出版商

Texada M, Jørgensen A, Christensen C, Koyama T, Malita A, Smith D, et al. A fat-tissue sensor couples growth to oxygen availability by remotely controlling insulin secretion. Nat Commun. 2019;10:1955 pubmed 出版商

Moncho Amor V, Pintado Berninches L, Ibanez de Caceres I, Martín Villar E, Quintanilla M, Chakravarty P, et al. Role of Dusp6 Phosphatase as a Tumor Suppressor in Non-Small Cell Lung Cancer. Int J Mol Sci. 2019;20: pubmed 出版商

Gui Y, Lu Q, Gu M, Wang M, Liang Y, Zhu X, et al. Fibroblast mTOR/PPARγ/HGF axis protects against tubular cell death and acute kidney injury. Cell Death Differ. 2019;: pubmed 出版商

Good A, Cannon C, Haemmerle M, Yang J, Stanescu D, Doliba N, et al. JUND regulates pancreatic β cell survival during metabolic stress. Mol Metab. 2019;25:95-106 pubmed 出版商

Parker S, Krantz J, Kwak E, Barker N, Deer C, Lee N, et al. Insulin Induces Microtubule Stabilization and Regulates the Microtubule Plus-End Tracking Protein Network in Adipocytes. Mol Cell Proteomics. 2019;: pubmed 出版商

Farina F, Ramkumar N, Brown L, Samandar Eweis D, Anstatt J, WARING T, et al. Local actin nucleation tunes centrosomal microtubule nucleation during passage through mitosis. EMBO J. 2019;38: pubmed 出版商

Wu Z, Qiu M, Guo Y, Zhao J, Liu Z, Wang H, et al. OTU deubiquitinase 4 is silenced and radiosensitizes non-small cell lung cancer cells via inhibiting DNA repair. Cancer Cell Int. 2019;19:99 pubmed 出版商

Emanuelli A, Manikoth Ayyathan D, Koganti P, Shah P, Apel Sarid L, Paolini B, et al. Altered Expression and Localization of Tumor Suppressive E3 Ubiquitin Ligase SMURF2 in Human Prostate and Breast Cancer. Cancers (Basel). 2019;11: pubmed 出版商

Siddiqi F, Menzies F, Lopez A, Stamatakou E, Karabiyik C, Ureshino R, et al. Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing. Nat Commun. 2019;10:1817 pubmed 出版商

Huang X, Xue H, Ma J, Zhang Y, Zhang J, Liu Y, et al. Salidroside ameliorates Adriamycin nephropathy in mice by inhibiting β-catenin activity. J Cell Mol Med. 2019;23:4443-4453 pubmed 出版商

Marcello E, Musardo S, Vandermeulen L, Pelucchi S, Gardoni F, Santo N, et al. Amyloid-β Oligomers Regulate ADAM10 Synaptic Localization Through Aberrant Plasticity Phenomena. Mol Neurobiol. 2019;: pubmed 出版商

Tsai J, Hsu W, Liu J, Chang C, Tang T. CEP120 interacts with C2CD3 and Talpid3 and is required for centriole appendage assembly and ciliogenesis. Sci Rep. 2019;9:6037 pubmed 出版商

Lau L, Porciuncula A, Yu A, Iwakura Y, David G. Uncoupling the Senescence-Associated Secretory Phenotype from Cell Cycle Exit via Interleukin-1 Inactivation Unveils Its Protumorigenic Role. Mol Cell Biol. 2019;39: pubmed 出版商

Maslon M, Braunschweig U, Aitken S, Mann A, Kilanowski F, Hunter C, et al. A slow transcription rate causes embryonic lethality and perturbs kinetic coupling of neuronal genes. EMBO J. 2019;38: pubmed 出版商

Wang Y, Brady K, Caiello B, Ackerson S, Stewart J. Human CST suppresses origin licensing and promotes AND-1/Ctf4 chromatin association. Life Sci Alliance. 2019;2: pubmed 出版商

Liao S, Kandasamy S, Zhu L, Fukunaga R. DEAD-box RNA helicase Belle post-transcriptionally promotes gene expression in an ATPase activity-dependent manner. RNA. 2019;: pubmed 出版商

Xu W, Gulvady A, Goreczny G, Olson E, Turner C. Paxillin-dependent regulation of apical-basal polarity in mammary gland morphogenesis. Development. 2019;146: pubmed 出版商

Scharner J, Qi S, Rigo F, Bennett C, Krainer A. Delivery of GalNAc-Conjugated Splice-Switching ASOs to Non-hepatic Cells through Ectopic Expression of Asialoglycoprotein Receptor. Mol Ther Nucleic Acids. 2019;16:313-325 pubmed 出版商

Rogerson C, Britton E, Withey S, Hanley N, Ang Y, Sharrocks A. Identification of a primitive intestinal transcription factor network shared between esophageal adenocarcinoma and its pre-cancerous precursor state. Genome Res. 2019;: pubmed 出版商

Chakraborty D, Felzen V, Hiebel C, Stürner E, Perumal N, Manicam C, et al. Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress. Redox Biol. 2019;24:101181 pubmed 出版商

Iershov A, Nemazanyy I, Alkhoury C, Girard M, Barth E, Cagnard N, et al. The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα. Nat Commun. 2019;10:1566 pubmed 出版商

Dilsizoglu Senol A, Pepe A, Grudina C, Sassoon N, Reiko U, Bousset L, et al. Effect of tolytoxin on tunneling nanotube formation and function. Sci Rep. 2019;9:5741 pubmed 出版商

Schwarzerová K, Bellinvia E, Martinek J, Sikorová L, Dostal V, Libusova L, et al. Tubulin is actively exported from the nucleus through the Exportin1/CRM1 pathway. Sci Rep. 2019;9:5725 pubmed 出版商

Gan C, Sam K, Yee P, Zainal N, Lee B, Abdul Rahman Z, et al. IFITM3 knockdown reduces the expression of CCND1 and CDK4 and suppresses the growth of oral squamous cell carcinoma cells. Cell Oncol (Dordr). 2019;: pubmed 出版商

Ho D, Lee H, Son I, Seol W. G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses. Anim Cells Syst (Seoul). 2019;23:106-111 pubmed 出版商

Ravindran S, Nalavadi V, Muddashetty R. BDNF Induced Translation of Limk1 in Developing Neurons Regulates Dendrite Growth by Fine-Tuning Cofilin1 Activity. Front Mol Neurosci. 2019;12:64 pubmed 出版商

Aparisi Rey A, Karaulanov E, Sharopov S, Arab K, Schäfer A, Gierl M, et al. Gadd45α modulates aversive learning through post-transcriptional regulation of memory-related mRNAs. EMBO Rep. 2019;20: pubmed 出版商

Celaya A, Sanchez Perez I, Bermúdez Muñoz J, Rodriguez de la Rosa L, Pintado Berninches L, Perona R, et al. Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss. elife. 2019;8: pubmed 出版商

Cho I, Hunter C, Ye S, Pongos A, Chan A. Combination of stem cell and gene therapy ameliorates symptoms in Huntington's disease mice. NPJ Regen Med. 2019;4:7 pubmed 出版商

Peñalver González B, Vallejo Rodríguez J, Mentxaka G, Fullaondo A, Iglesias Ara A, Field S, et al. Golgi Oncoprotein GOLPH3 Gene Expression Is Regulated by Functional E2F and CREB/ATF Promoter Elements. Genes (Basel). 2019;10: pubmed 出版商

Zarei M, Pujol E, Quesada López T, Villarroya F, Barroso E, Vazquez S, et al. Oral administration of a new HRI activator as a new strategy to improve high-fat-diet-induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21. Br J Pharmacol. 2019;176:2292-2305 pubmed 出版商

El Houjeiri L, Possik E, Vijayaraghavan T, Paquette M, Martina J, Kazan J, et al. The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance. Cell Rep. 2019;26:3613-3628.e6 pubmed 出版商

Zinn A, Goicoechea S, Kreider Letterman G, Maity D, Awadia S, Cedeno Rosario L, et al. The small GTPase RhoG regulates microtubule-mediated focal adhesion disassembly. Sci Rep. 2019;9:5163 pubmed 出版商

Tsalikis J, Abdel Nour M, Farahvash A, Sorbara M, Poon S, Philpott D, et al. Isoginkgetin, a Natural Biflavonoid Proteasome Inhibitor, Sensitizes Cancer Cells to Apoptosis via Disruption of Lysosomal Homeostasis and Impaired Protein Clearance. Mol Cell Biol. 2019;39: pubmed 出版商

Uzair I, Conte Grand J, Flamini M, Sanchez A. Molecular Actions of Thyroid Hormone on Breast Cancer Cell Migration and Invasion via Cortactin/N-WASP. Front Endocrinol (Lausanne). 2019;10:139 pubmed 出版商

Yamaguchi T, Hayashi M, Ida L, Yamamoto M, Lu C, Kajino T, et al. ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma. Oncogene. 2019;: pubmed 出版商

Akande O, Damle P, Pop M, Sherman N, Szomju B, Litovchick L, et al. DBC1 Regulates p53 Stability via Inhibition of CBP-Dependent p53 Polyubiquitination. Cell Rep. 2019;26:3323-3335.e4 pubmed 出版商

Aziz K, Limzerwala J, Sturmlechner I, Hurley E, Zhang C, Jeganathan K, et al. Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice. Gastroenterology. 2019;: pubmed 出版商

Wiegand C, Abel M, Hipler U, Elsner P. Effect of non-adhering dressings on promotion of fibroblast proliferation and wound healing in vitro. Sci Rep. 2019;9:4320 pubmed 出版商

Li K, Qiu C, Sun P, Liu D, Wu T, Wang K, et al. Ets1-Mediated Acetylation of FoxO1 Is Critical for Gluconeogenesis Regulation during Feed-Fast Cycles. Cell Rep. 2019;26:2998-3010.e5 pubmed 出版商

Hong A, Tseng Y, Wala J, Kim W, Kynnap B, Doshi M, et al. Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition. elife. 2019;8: pubmed 出版商

Crerar H, Scott Solomon E, Bodkin Clarke C, Andreassi C, Hazbon M, Logie E, et al. Regulation of NGF Signaling by an Axonal Untranslated mRNA. Neuron. 2019;102:553-563.e8 pubmed 出版商

Ichisima J, Suzuki N, Samata B, Awaya T, Takahashi J, Hagiwara M, et al. Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model. J Hum Genet. 2019;64:445-458 pubmed 出版商

Zhang D, Liu X, Xu X, Xu J, Yi Z, Shan B, et al. HPCAL1 promotes glioblastoma proliferation via activation of Wnt/β-catenin signalling pathway. J Cell Mol Med. 2019;23:3108-3117 pubmed 出版商

Böhme M, McCarthy A, Grasskamp A, Beuschel C, Goel P, Jusyte M, et al. Rapid active zone remodeling consolidates presynaptic potentiation. Nat Commun. 2019;10:1085 pubmed 出版商

Gleason C, Oses Prieto J, Li K, Saha B, Situ G, Burlingame A, et al. Phosphorylation at distinct subcellular locations underlies specificity in mTORC2-mediated activation of SGK1 and Akt. J Cell Sci. 2019;132: pubmed 出版商

Zhou R, Yang Y, Park S, Seo Y, Jung S, Kim K, et al. p300/CBP-associated factor promotes autophagic degradation of δ-catenin through acetylation and decreases prostate cancer tumorigenicity. Sci Rep. 2019;9:3351 pubmed 出版商

Li L, Wu S, Yan M, Lian Q, Ge R, Cheng C. Regulation of blood-testis barrier dynamics by the mTORC1/rpS6 signaling complex: An in vitro study. Asian J Androl. 2019;21:365-375 pubmed 出版商

Mylavarapu S, Kumar H, Kumari S, Sravanthi L, Jain M, Basu A, et al. Activation of Epithelial-Mesenchymal Transition and Altered β-Catenin Signaling in a Novel Indian Colorectal Carcinoma Cell Line. Front Oncol. 2019;9:54 pubmed 出版商

Pudełek M, Catapano J, Kochanowski P, Mrowiec K, Janik Olchawa N, Czyz J, et al. Therapeutic potential of monoterpene α-thujone, the main compound of Thuja occidentalis L. essential oil, against malignant glioblastoma multiforme cells in vitro. Fitoterapia. 2019;134:172-181 pubmed 出版商

Choi S, Martínez T, Kim S, Donaldson C, Shokhirev M, Saghatelian A, et al. CDK12 phosphorylates 4E-BP1 to enable mTORC1-dependent translation and mitotic genome stability. Genes Dev. 2019;33:418-435 pubmed 出版商

Chen S, Yue J, Zhang J, Jiang M, Hu T, Leng W, et al. Continuous exposure of isoprenaline inhibits myoblast differentiation and fusion through PKA/ERK1/2-FOXO1 signaling pathway. Stem Cell Res Ther. 2019;10:70 pubmed 出版商

Duciel L, Anezo O, Mandal K, Laurent C, Planque N, Coquelle F, et al. Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) promotes the aggressiveness of human uveal melanoma through dephosphorylation of CRMP2. Sci Rep. 2019;9:2990 pubmed 出版商

Göktuna S. IKBKE inhibits TSC1 to activate the mTOR/S6K pathway for oncogenic transformation. Turk J Biol. 2018;42:268-278 pubmed 出版商

Antas P, Novellasdemunt L, Kucharska A, Massie I, Carvalho J, Oukrif D, et al. SH3BP4 Regulates Intestinal Stem Cells and Tumorigenesis by Modulating β-Catenin Nuclear Localization. Cell Rep. 2019;26:2266-2273.e4 pubmed 出版商

Li L, Mao B, Yan M, Wu S, Ge R, Lian Q, et al. Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organization. Cell Death Dis. 2019;10:194 pubmed 出版商

Baron D, Matheny T, Lin Y, Leszyk J, Kenna K, Gall K, et al. Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS. Hum Mol Genet. 2019;: pubmed 出版商

Grigelioniene G, Suzuki H, Taylan F, Mirzamohammadi F, Borochowitz Z, Ayturk U, et al. Gain-of-function mutation of microRNA-140 in human skeletal dysplasia. Nat Med. 2019;25:583-590 pubmed 出版商

Senturk M, Lin G, Zuo Z, Mao D, Watson E, Mikos A, et al. Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification. Nat Cell Biol. 2019;21:384-396 pubmed 出版商

Carim S, Ben El Kadhi K, Yan G, Sweeney S, Hickson G, Carreno S, et al. IPIP27 Coordinates PtdIns(4,5)P2 Homeostasis for Successful Cytokinesis. Curr Biol. 2019;: pubmed 出版商

Zhao M, Xie J, Shu W, Wang H, Bi J, Jiang W, et al. MiR-15b and miR-322 inhibit SETD3 expression to repress muscle cell differentiation. Cell Death Dis. 2019;10:183 pubmed 出版商

Gültekin Y, Steller H. Axin proteolysis by Iduna is required for the regulation of stem cell proliferation and intestinal homeostasis in Drosophila. Development. 2019;146: pubmed 出版商

Liao M, Liao W, Xu N, Li B, Liu F, Zhang S, et al. LncRNA EPB41L4A-AS1 regulates glycolysis and glutaminolysis by mediating nucleolar translocation of HDAC2. EBioMedicine. 2019;41:200-213 pubmed 出版商

Mirkovic M, Guilgur L, Tavares A, Passagem Santos D, Oliveira R. Induced aneuploidy in neural stem cells triggers a delayed stress response and impairs adult life span in flies. PLoS Biol. 2019;17:e3000016 pubmed 出版商

Legge D, Shephard A, Collard T, Greenhough A, Chambers A, Clarkson R, et al. BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells. Dis Model Mech. 2019;12: pubmed 出版商

Lampi Y, Van Looveren D, Vranckx L, Thiry I, Bornschein S, Debyser Z, et al. Targeted editing of the PSIP1 gene encoding LEDGF/p75 protects cells against HIV infection. Sci Rep. 2019;9:2389 pubmed 出版商

Izumi H, Li Y, Shibaki M, Mori D, Yasunami M, Sato S, et al. Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region. Sci Rep. 2019;9:2236 pubmed 出版商

Shi P, Wang Y, Huang Y, Zhang C, Li Y, Liu Y, et al. Arp2/3-branched actin regulates microtubule acetylation level and affects mitochondrial distribution. J Cell Sci. 2019;: pubmed 出版商

Felipe Abrio B, Verdugo Sivianes E, Saez C, Carnero A. Loss of MYBBP1A Induces Cancer Stem Cell Activity in Renal Cancer. Cancers (Basel). 2019;11: pubmed 出版商

Kaya Aksoy E, Cingöz A, Senbabaoglu F, Seker F, Sur Erdem I, Kayabolen A, et al. The pro-apoptotic Bcl-2 family member Harakiri (HRK) induces cell death in glioblastoma multiforme. Cell Death Discov. 2019;5:64 pubmed 出版商

Ibrahim D, Ko J, Iwata W, Okumichi H, Kiuchi Y. An in vitro study of scarring formation mediated by human Tenon fibroblasts: Effect of Y-27632, a Rho kinase inhibitor. Cell Biochem Funct. 2019;37:113-124 pubmed 出版商

Di Emidio G, Santini S, D Alessandro A, Vetuschi A, Sferra R, Artini P, et al. SIRT1 participates in the response to methylglyoxal-dependent glycative stress in mouse oocytes and ovary. Biochim Biophys Acta Mol Basis Dis. 2019;1865:1389-1401 pubmed 出版商

Estañ M, Fernández Núñez E, Zaki M, Esteban M, Donkervoort S, Hawkins C, et al. Recessive mutations in muscle-specific isoforms of FXR1 cause congenital multi-minicore myopathy. Nat Commun. 2019;10:797 pubmed 出版商

Maio N, Kim K, Holmes Hampton G, Singh A, Rouault T. Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis. Haematologica. 2019;: pubmed 出版商

Webster K, Henke K, Ingalls D, Nahrin A, Harris M, Siegfried K. Cyclin-dependent kinase 21 is a novel regulator of proliferation and meiosis in the male germline of zebrafish. Reproduction. 2018;157:383-398 pubmed 出版商

Hepburn A, Steele R, Veeratterapillay R, Wilson L, Kounatidou E, Barnard A, et al. The induction of core pluripotency master regulators in cancers defines poor clinical outcomes and treatment resistance. Oncogene. 2019;38:4412-4424 pubmed 出版商

Araki K, Kawauchi K, Sugimoto W, Tsuda D, Oda H, Yoshida R, et al. Mitochondrial protein E2F3d, a distinctive E2F3 product, mediates hypoxia-induced mitophagy in cancer cells. Commun Biol. 2019;2:3 pubmed 出版商

Takenaka N, Araki N, Satoh T. Involvement of the protein kinase Akt2 in insulin-stimulated Rac1 activation leading to glucose uptake in mouse skeletal muscle. PLoS ONE. 2019;14:e0212219 pubmed 出版商

Hu J, Lessard C, Longstaff C, O Brien M, Palmer K, Reinholdt L, et al. ENU-induced mutant allele of Dnah1, ferf1, causes abnormal sperm behavior and fertilization failure in mice. Mol Reprod Dev. 2019;86:416-425 pubmed 出版商

Stefanski A, Martinez N, Peterson L, Callahan T, Treacy E, Luck M, et al. Murine trophoblast-derived and pregnancy-associated exosome-enriched extracellular vesicle microRNAs: Implications for placenta driven effects on maternal physiology. PLoS ONE. 2019;14:e0210675 pubmed 出版商

Pierce E, Graham B, Stiff M, Osborne J, Haigler C. Cultures of Gossypium barbadense cotton ovules offer insights into the microtubule-mediated control of fiber cell expansion. Planta. 2019;249:1551-1563 pubmed 出版商

Wehrle A, Witkos T, Unger S, Schneider J, Follit J, Hermann J, et al. Hypomorphic mutations of TRIP11 cause odontochondrodysplasia. JCI Insight. 2019;4: pubmed 出版商

Sanchez Ruderisch H, Queirós A, Fliegner D, Eschen C, Kararigas G, Regitz Zagrosek V. Sex-specific regulation of cardiac microRNAs targeting mitochondrial proteins in pressure overload. Biol Sex Differ. 2019;10:8 pubmed 出版商

Hoppstädter J, Diesel B, Linnenberger R, Hachenthal N, Flamini S, Minet M, et al. Amplified Host Defense by Toll-Like Receptor-Mediated Downregulation of the Glucocorticoid-Induced Leucine Zipper (GILZ) in Macrophages. Front Immunol. 2018;9:3111 pubmed 出版商

Ho D, Seol W, Son I. Upregulation of the p53-p21 pathway by G2019S LRRK2 contributes to the cellular senescence and accumulation of α-synuclein. Cell Cycle. 2019;18:467-475 pubmed 出版商

Sanidas I, Morris R, Fella K, Rumde P, Boukhali M, Tai E, et al. A Code of Mono-phosphorylation Modulates the Function of RB. Mol Cell. 2019;73:985-1000.e6 pubmed 出版商

Vacca F, Vossio S, Mercier V, Moreau D, Johnson S, Scott C, et al. Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells. J Lipid Res. 2019;60:832-843 pubmed 出版商

Villafañez F, García I, Carbajosa S, Pansa M, Mansilla S, Llorens M, et al. AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress. Oncogene. 2019;38:4310-4324 pubmed 出版商

Rivero S, Gómez Marín E, Guerrero Martínez J, García Martínez J, Reyes J. TBL1 is required for the mesenchymal phenotype of transformed breast cancer cells. Cell Death Dis. 2019;10:95 pubmed 出版商

de Pins B, Cifuentes Diaz C, Farah A, López Molina L, Montalban E, Sancho Balsells A, et al. Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease. J Neurosci. 2019;39:2441-2458 pubmed 出版商

Kern S, Truebenbach I, Höhn M, Gorges J, Kazmaier U, Zahler S, et al. Combined antitumoral effects of pretubulysin and methotrexate. Pharmacol Res Perspect. 2019;7:e00460 pubmed 出版商

Tabariès S, McNulty A, Ouellet V, Annis M, Dessureault M, Vinette M, et al. Afadin cooperates with Claudin-2 to promote breast cancer metastasis. Genes Dev. 2019;33:180-193 pubmed 出版商

Stewart M, Lau P, Banks G, Bains R, Castroflorio E, Oliver P, et al. Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities. Dis Model Mech. 2019;12: pubmed 出版商

Wu Z, Qiu M, Mi Z, Meng M, Guo Y, Jiang X, et al. WT1-interacting protein inhibits cell proliferation and tumorigenicity in non-small-cell lung cancer via the AKT/FOXO1 axis. Mol Oncol. 2019;13:1059-1074 pubmed 出版商

Isgrig K, McDougald D, Zhu J, Wang H, Bennett J, Chien W. AAV2.7m8 is a powerful viral vector for inner ear gene therapy. Nat Commun. 2019;10:427 pubmed 出版商

Abe Y, Suzuki Y, Kawamura K, Tanaka N. MEP50/PRMT5-mediated methylation activates GLI1 in Hedgehog signalling through inhibition of ubiquitination by the ITCH/NUMB complex. Commun Biol. 2019;2:23 pubmed 出版商

Rabouw H, Langereis M, Anand A, Visser L, de Groot R, Walter P, et al. Small molecule ISRIB suppresses the integrated stress response within a defined window of activation. Proc Natl Acad Sci U S A. 2019;116:2097-2102 pubmed 出版商

Dwivedi D, Kumari A, Rathi S, Mylavarapu S, Sharma M. The dynein adaptor Hook2 plays essential roles in mitotic progression and cytokinesis. J Cell Biol. 2019;: pubmed 出版商

Wen S, Lima L, Lobb R, Norris E, Hastie M, Krumeich S, et al. Breast Cancer-Derived Exosomes Reflect the Cell-of-Origin Phenotype. Proteomics. 2019;19:e1800180 pubmed 出版商

Li Z, Zhang X, Guo Z, Zhong Y, Wang P, Li J, et al. SIRT6 Suppresses NFATc4 Expression and Activation in Cardiomyocyte Hypertrophy. Front Pharmacol. 2018;9:1519 pubmed 出版商

Di Giacomo S, Briz O, Monte M, Sanchez Vicente L, Abete L, Lozano E, et al. Chemosensitization of hepatocellular carcinoma cells to sorafenib by β-caryophyllene oxide-induced inhibition of ABC export pumps. Arch Toxicol. 2019;93:623-634 pubmed 出版商

Nagano T, Yamao S, Terachi A, Yarimizu H, Itoh H, Katasho R, et al. d-amino acid oxidase promotes cellular senescence via the production of reactive oxygen species. Life Sci Alliance. 2019;2: pubmed 出版商

Jiménez M, Urtasun R, Elizalde M, Azkona M, Latasa M, Uriarte I, et al. Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins. Nucleic Acids Res. 2019;47:3450-3466 pubmed 出版商

Lodyga M, Cambridge E, Karvonen H, Pakshir P, Wu B, Boo S, et al. Cadherin-11-mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β. Sci Signal. 2019;12: pubmed 出版商

Jiménez López J, El Hammadi M, Ortiz R, Cayero Otero M, Cabeza L, Perazzoli G, et al. A novel nanoformulation of PLGA with high non-ionic surfactant content improves in vitro and in vivo PTX activity against lung cancer. Pharmacol Res. 2019;141:451-465 pubmed 出版商

Karampini E, Schillemans M, Hofman M, van Alphen F, de Boer M, Kuijpers T, et al. Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells. Haematologica. 2019;: pubmed 出版商

Garrido Rodríguez M, Ortea I, Calzado M, Munoz E, Garcia V. SWATH proteomic profiling of prostate cancer cells identifies NUSAP1 as a potential molecular target for Galiellalactone. J Proteomics. 2019;193:217-229 pubmed 出版商

Zhu Q, Fang L, Heuberger J, Kranz A, Schipper J, Scheckenbach K, et al. The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer. Cell Rep. 2019;26:415-428.e5 pubmed 出版商

Picco M, Castro M, Quezada M, Barbero G, Villanueva M, Fernández N, et al. STAT3 enhances the constitutive activity of AGC kinases in melanoma by transactivating PDK1. Cell Biosci. 2019;9:3 pubmed 出版商

Morgan M, Kabayama Y, Much C, Ivanova I, Di Giacomo M, Auchynnikava T, et al. A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis. Cell Res. 2019;29:221-232 pubmed 出版商

Del Olmo T, Lauzier A, Normandin C, Larcher R, Lecours M, Jean D, et al. APEX2-mediated RAB proximity labeling identifies a role for RAB21 in clathrin-independent cargo sorting. EMBO Rep. 2019;20: pubmed 出版商

Budka J, Ferris M, Capone M, Hollenhorst P. Common ELF1 deletion in prostate cancer bolsters oncogenic ETS function, inhibits senescence and promotes docetaxel resistance. Genes Cancer. 2018;9:198-214 pubmed 出版商

Tona R, Chen W, Nakano Y, Reyes L, Petralia R, Wang Y, et al. The phenotypic landscape of a Tbc1d24 mutant mouse includes convulsive seizures resembling human early infantile epileptic encephalopathy. Hum Mol Genet. 2019;28:1530-1547 pubmed 出版商

Broekema M, Massink M, Donato C, de Ligt J, Schaarschmidt J, Borgman A, et al. Natural helix 9 mutants of PPARγ differently affect its transcriptional activity. Mol Metab. 2019;20:115-127 pubmed 出版商

Porokuokka L, Virtanen H, Lindén J, Sidorova Y, Danilova T, Lindahl M, et al. Gfra1 Underexpression Causes Hirschsprung's Disease and Associated Enterocolitis in Mice. Cell Mol Gastroenterol Hepatol. 2019;7:655-678 pubmed 出版商

Yang X, Lou Y, Wang M, Liu C, Liu Y, Huang W. miR‑675 promotes colorectal cancer cell growth dependent on tumor suppressor DMTF1. Mol Med Rep. 2019;19:1481-1490 pubmed 出版商

Cejas R, Lorenz V, Garay Y, Irazoqui F. Biosynthesis of O-N-acetylgalactosamine glycans in the human cell nucleus. J Biol Chem. 2019;294:2997-3011 pubmed 出版商

Tornillo G, Knowlson C, Kendrick H, Cooke J, Mirza H, Aurrekoetxea Rodríguez I, et al. Dual Mechanisms of LYN Kinase Dysregulation Drive Aggressive Behavior in Breast Cancer Cells. Cell Rep. 2018;25:3674-3692.e10 pubmed 出版商

Ramani A, Mariappan A, Gottardo M, Mandad S, Urlaub H, Avidor Reiss T, et al. Plk1/Polo Phosphorylates Sas-4 at the Onset of Mitosis for an Efficient Recruitment of Pericentriolar Material to Centrosomes. Cell Rep. 2018;25:3618-3630.e6 pubmed 出版商

Tiedemann K, Sadvakassova G, Mikolajewicz N, Juhas M, Sabirova Z, Tabariès S, et al. Exosomal Release of L-Plastin by Breast Cancer Cells Facilitates Metastatic Bone Osteolysis. Transl Oncol. 2019;12:462-474 pubmed 出版商

Singh R, Haka A, Bhardwaj P, Zha X, Maxfield F. Dynamic Actin Reorganization and Vav/Cdc42-Dependent Actin Polymerization Promote Macrophage Aggregated LDL (Low-Density Lipoprotein) Uptake and Catabolism. Arterioscler Thromb Vasc Biol. 2018;:ATVBAHA118312087 pubmed 出版商

Antúnez Mojica M, Rojas Sepúlveda A, Mendieta Serrano M, González Maya L, Marquina S, Salas Vidal E, et al. Lignans from Bursera fagaroides Affect In Vivo Cell Behavior by Disturbing the Tubulin Cytoskeleton in Zebrafish Embryos. Molecules. 2018;24: pubmed 出版商

Zhao Z, Kesti T, Uğurlu H, Baur A, Fagerlund R, Saksela K. Tyrosine phosphorylation directs TACE into extracellular vesicles via unconventional secretion. Traffic. 2019;20:202-212 pubmed 出版商

Guijarro T, Magro Lopez E, Manso J, Garcia Martinez R, Fernandez Aceñero M, Liste I, et al. Detrimental pro-senescence effects of vitamin D on lung fibrosis. Mol Med. 2018;24:64 pubmed 出版商

Nagy S, Maurer G, Hentze J, Rose M, Werge T, Rewitz K. AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance. PLoS Genet. 2018;14:e1007623 pubmed 出版商

Todaro F, Campolo F, Barrios F, Pellegrini M, Di Cesare S, Tessarollo L, et al. Regulation of Kit Expression in Early Mouse Embryos and ES Cells. Stem Cells. 2019;37:332-344 pubmed 出版商

John C, Grune J, Ott C, Nowotny K, Deubel S, Kühne A, et al. Sex Differences in Cardiac Mitochondria in the New Zealand Obese Mouse. Front Endocrinol (Lausanne). 2018;9:732 pubmed 出版商

Normand S, Waldschmitt N, Neerincx A, Martinez Torres R, Chauvin C, Couturier Maillard A, et al. Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens. Nat Commun. 2018;9:5338 pubmed 出版商

Yin W, Satkunendran T, Mo R, Morrissy S, Zhang X, Huang E, et al. Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma. Dev Cell. 2019;48:167-183.e5 pubmed 出版商

Le Dily F, Vidal E, Cuartero Y, Quilez J, Nacht A, Vicent G, et al. Hormone-control regions mediate steroid receptor-dependent genome organization. Genome Res. 2019;29:29-39 pubmed 出版商

Park S, Lim Y, Lee D, Elvira R, Lee J, Lee M, et al. Modulation of Protein Synthesis by eIF2α Phosphorylation Protects Cell from Heat Stress-Mediated Apoptosis. Cells. 2018;7: pubmed 出版商

Menzies S, Volkmar N, van den Boomen D, Timms R, Dickson A, Nathan J, et al. The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1. elife. 2018;7: pubmed 出版商

Perrucci G, Barbagallo V, Corlianò M, Tosi D, Santoro R, Nigro P, et al. Integrin ανβ5 in vitro inhibition limits pro-fibrotic response in cardiac fibroblasts of spontaneously hypertensive rats. J Transl Med. 2018;16:352 pubmed 出版商

Lafarga V, Sung H, Haneke K, Roessig L, Pauleau A, Bruer M, et al. TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress. EMBO Rep. 2019;20: pubmed 出版商

Packer L, Stehbens S, Bonazzi V, Gunter J, Ju R, Ward M, et al. Bcl-2 inhibitors enhance FGFR inhibitor-induced mitochondrial-dependent cell death in FGFR2-mutant endometrial cancer. Mol Oncol. 2019;13:738-756 pubmed 出版商

Relic B, Charlier E, Deroyer C, Malaise O, Crine Y, Neuville S, et al. Serum starvation raises turnover of phosphorylated p62/SQSTM1 (Serine 349), reveals expression of proteasome and N-glycanase1 interactive protein RAD23B and sensitizes human synovial fibroblasts to BAY 11-7085-induced cell death. Oncotarget. 2018;9:35830-35843 pubmed 出版商

Shirai Y, Mizutani A, Nishijima S, Horie M, Kikuguchi C, Elisseeva O, et al. CNOT3 targets negative cell cycle regulators in non-small cell lung cancer development. Oncogene. 2019;38:2580-2594 pubmed 出版商

Khan M, Muzumdar D, Shiras A. Attenuation of Tumor Suppressive Function of FBXO16 Ubiquitin Ligase Activates Wnt Signaling In Glioblastoma. Neoplasia. 2019;21:106-116 pubmed 出版商

Varela Eirin M, Varela Vazquez A, Guitián Caamaño A, Paíno C, Mato V, Largo R, et al. Targeting of chondrocyte plasticity via connexin43 modulation attenuates cellular senescence and fosters a pro-regenerative environment in osteoarthritis. Cell Death Dis. 2018;9:1166 pubmed 出版商

Ciuba K, Hawkes W, Tojkander S, Kogan K, Engel U, Iskratsch T, et al. Calponin-3 is critical for coordinated contractility of actin stress fibers. Sci Rep. 2018;8:17670 pubmed 出版商

Ikeuchi T, de Vega S, Forcinito P, Doyle A, Amaral J, Rodriguez I, et al. Extracellular Protein Fibulin-7 and Its C-Terminal Fragment Have In Vivo Antiangiogenic Activity. Sci Rep. 2018;8:17654 pubmed 出版商

Ling H, Peng L, Wang J, Rahhal R, Seto E. Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication. Cell Rep. 2018;25:2851-2865.e3 pubmed 出版商

Bainor A, Saini S, Calderon A, Casado Polanco R, Giner Ramirez B, Moncada C, et al. The HDAC-Associated Sin3B Protein Represses DREAM Complex Targets and Cooperates with APC/C to Promote Quiescence. Cell Rep. 2018;25:2797-2807.e8 pubmed 出版商

Gold D, Katsuki T, Li Y, Yan X, Regulski M, Ibberson D, et al. The genome of the jellyfish Aurelia and the evolution of animal complexity. Nat Ecol Evol. 2019;3:96-104 pubmed 出版商

Phan A, Thomas C, Chakraborty M, Berry J, Kamasawa N, Davis R. Stromalin Constrains Memory Acquisition by Developmentally Limiting Synaptic Vesicle Pool Size. Neuron. 2019;101:103-118.e5 pubmed 出版商

Solís C, Morales T. Lactation diminishes lesion-induced permeability of tracers into the brain. Brain Res Bull. 2018;144:92-100 pubmed 出版商

Karole A, Chodisetty S, Ali A, Kumari N, Tyagi S. Novel sub-cellular localizations and intra-molecular interactions may define new functions of Mixed Lineage Leukemia protein. Cell Cycle. 2018;17:2684-2696 pubmed 出版商

Doyle T, Moncorgé O, Bonaventure B, Pollpeter D, Lussignol M, Tauziet M, et al. The interferon-inducible isoform of NCOA7 inhibits endosome-mediated viral entry. Nat Microbiol. 2018;3:1369-1376 pubmed 出版商

Marques M, Melo J, Cavadas B, Mendes N, Pereira L, Carneiro F, et al. Afadin Downregulation by Helicobacter pylori Induces Epithelial to Mesenchymal Transition in Gastric Cells. Front Microbiol. 2018;9:2712 pubmed 出版商

Sharma P, Lioutas A, Fernandez Fuentes N, Quilez J, Carbonell Caballero J, Wright R, et al. Arginine Citrullination at the C-Terminal Domain Controls RNA Polymerase II Transcription. Mol Cell. 2019;73:84-96.e7 pubmed 出版商

Zhu H, Zhang W, Zhao Y, Shu X, Wang W, Wang D, et al. GSK3β-mediated tau hyperphosphorylation triggers diabetic retinal neurodegeneration by disrupting synaptic and mitochondrial functions. Mol Neurodegener. 2018;13:62 pubmed 出版商

Marié I, Chang H, Levy D. HDAC stimulates gene expression through BRD4 availability in response to IFN and in interferonopathies. J Exp Med. 2018;215:3194-3212 pubmed 出版商

Jang J, Oh H, Nam D, Seol W, Seo M, Park S, et al. Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity. Anim Cells Syst (Seoul). 2018;22:273-280 pubmed 出版商

Arnandis T, Monteiro P, Adams S, Bridgeman V, Rajeeve V, Gadaleta E, et al. Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion. Dev Cell. 2018;47:409-424.e9 pubmed 出版商

Berto M, Jean V, Zwart W, Picard D. ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1. Life Sci Alliance. 2018;1:e201800055 pubmed 出版商

Vigolo E, Markó L, Hinze C, Muller D, Schmidt Ullrich R, Schmidt Ott K. Canonical BMP signaling in tubular cells mediates recovery after acute kidney injury. Kidney Int. 2019;95:108-122 pubmed 出版商

Stoupa A, Adam F, Kariyawasam D, Strassel C, Gawade S, Szinnai G, et al. TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology. EMBO Mol Med. 2018;10: pubmed 出版商

Artelt N, Siegerist F, Ritter A, Grisk O, Schlüter R, Endlich K, et al. Comparative Analysis of Podocyte Foot Process Morphology in Three Species by 3D Super-Resolution Microscopy. Front Med (Lausanne). 2018;5:292 pubmed 出版商

Dogar A, Pauchard Batschulat R, Grisoni Neupert B, Richman L, Paillusson A, Pradervand S, et al. Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each. PLoS ONE. 2018;13:e0206823 pubmed 出版商

Litvinchuk A, Wan Y, Swartzlander D, Chen F, Cole A, Propson N, et al. Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer's Disease. Neuron. 2018;100:1337-1353.e5 pubmed 出版商

Hu L, Huang H, Hei M, Yang Y, Li S, Liu Y, et al. Structural analysis of fungal CENP-H/I/K homologs reveals a conserved assembly mechanism underlying proper chromosome alignment. Nucleic Acids Res. 2019;47:468-479 pubmed 出版商

Park S, Mansur R, Lee Y, Lee J, Seo M, Choi A, et al. Liraglutide Activates mTORC1 Signaling and AMPA Receptors in Rat Hippocampal Neurons Under Toxic Conditions. Front Neurosci. 2018;12:756 pubmed 出版商

Revinski D, Zaragosi L, Boutin C, Ruiz García S, Deprez M, Thomé V, et al. CDC20B is required for deuterosome-mediated centriole production in multiciliated cells. Nat Commun. 2018;9:4668 pubmed 出版商

Xia Y, Huang N, Chen Z, Li F, Fan G, Ma D, et al. CCDC102B functions in centrosome linker assembly and centrosome cohesion. J Cell Sci. 2018;131: pubmed 出版商

Lenis T, Hu J, Ng S, Jiang Z, Sarfare S, Lloyd M, et al. Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration. Proc Natl Acad Sci U S A. 2018;115:E11120-E11127 pubmed 出版商

Hirota T, Blakeley P, Sangrithi M, Mahadevaiah S, Encheva V, Snijders A, et al. SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice. Dev Cell. 2018;47:645-659.e6 pubmed 出版商

Cattin M, Deeke S, Dick S, Verret Borsos Z, Tennakoon G, Gupta R, et al. Expression of murine muscle-enriched A-type lamin-interacting protein (MLIP) is regulated by tissue-specific alternative transcription start sites. J Biol Chem. 2018;293:19761-19770 pubmed 出版商

Lincoln F, Imig D, Boccellato C, Juric V, Noonan J, Kontermann R, et al. Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism. Cell Death Dis. 2018;9:1112 pubmed 出版商

Li Q, Saito T, Martínez García M, Deshong A, Nadarajan S, Lawrence K, et al. The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans. PLoS Genet. 2018;14:e1007701 pubmed 出版商

Witwicki R, Ekram M, Qiu X, Janiszewska M, Shu S, Kwon M, et al. TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer. Cell Rep. 2018;25:1255-1267.e5 pubmed 出版商

Higashi T, Stephenson R, Miller A. Comprehensive analysis of formin localization in Xenopus epithelial cells. Mol Biol Cell. 2019;30:82-95 pubmed 出版商

Tan Z, Chan Y, Chua Y, Rutledge S, Pavelka N, Cimini D, et al. Environmental stresses induce karyotypic instability in colorectal cancer cells. Mol Biol Cell. 2019;30:42-55 pubmed 出版商

Torgovnick A, Schiavi A, Shaik A, Kassahun H, Maglioni S, Rea S, et al. BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in Caenorhabditis elegans. EMBO Rep. 2018;19: pubmed 出版商

Pillozzi S, Bernini A, Spiga O, Lelli B, Petroni G, Bracci L, et al. Peptides and small molecules blocking the CXCR4/CXCL12 axis overcome bone marrow‑induced chemoresistance in acute leukemias. Oncol Rep. 2019;41:312-324 pubmed 出版商

Rageot D, Bohnacker T, Melone A, Langlois J, Borsari C, Hillmann P, et al. Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1/2 Inhibitor for Cancer and Neurological Disorders. J Med Chem. 2018;61:10084-10105 pubmed 出版商

Yan C, Wang F, Peng Y, Williams C, Jenkins B, Wildonger J, et al. Microtubule Acetylation Is Required for Mechanosensation in Drosophila. Cell Rep. 2018;25:1051-1065.e6 pubmed 出版商

Tang J, Shi N, Dong K, Brown S, Coleman A, Boegehold M, et al. Response Gene to Complement 32 Maintains Blood Pressure Homeostasis by Regulating α-Adrenergic Receptor Expression. Circ Res. 2018;123:1080-1090 pubmed 出版商

Zhou Y, Xiao L, Tang S. Annexin A2 and FTH1 are potential biomarkers for lupus nephritis. Exp Ther Med. 2018;16:3766-3776 pubmed 出版商

Piquet S, Le Parc F, Bai S, Chevallier O, Adam S, Polo S. The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling and Repair of DNA Damage. Mol Cell. 2018;72:888-901.e7 pubmed 出版商

Vezain M, Lecuyer M, Rubio M, Dupé V, Ratié L, David V, et al. A de novo variant in ADGRL2 suggests a novel mechanism underlying the previously undescribed association of extreme microcephaly with severely reduced sulcation and rhombencephalosynapsis. Acta Neuropathol Commun. 2018;6:109 pubmed 出版商

Simhadri S, Vincelli G, Huo Y, Misenko S, Foo T, Ahlskog J, et al. PALB2 connects BRCA1 and BRCA2 in the G2/M checkpoint response. Oncogene. 2019;38:1585-1596 pubmed 出版商

Van Dijk J, Bompard G, Cau J, Kunishima S, Rabeharivelo G, Mateos Langerak J, et al. Microtubule polyglutamylation and acetylation drive microtubule dynamics critical for platelet formation. BMC Biol. 2018;16:116 pubmed 出版商

Wood T, Barry J, Yang Z, Cepeda C, Levine M, Gray M. Mutant huntingtin reduction in astrocytes slows disease progression in the BACHD conditional Huntington's disease mouse model. Hum Mol Genet. 2019;28:487-500 pubmed 出版商

Boyle A, Rinaldi S, Rossi A, Saunders P, Norman J. Repurposing simvastatin as a therapy for preterm labor: evidence from preclinical models. FASEB J. 2019;33:2743-2758 pubmed 出版商

Abreu C, Prakash R, Romanienko P, Roig I, Keeney S, Jasin M. Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination. Nat Commun. 2018;9:3961 pubmed 出版商

Cortone G, Zheng G, Pensieri P, Chiappetta V, Tatè R, Malacaria E, et al. Interaction of the Warsaw breakage syndrome DNA helicase DDX11 with the replication fork-protection factor Timeless promotes sister chromatid cohesion. PLoS Genet. 2018;14:e1007622 pubmed 出版商

Verde G, de Llobet L, Wright R, Quilez J, Peiro S, Le Dily F, et al. Unliganded Progesterone Receptor Governs Estrogen Receptor Gene Expression by Regulating DNA Methylation in Breast Cancer Cells. Cancers (Basel). 2018;10: pubmed 出版商

Fets L, Driscoll P, Grimm F, Jain A, Nunes P, Gounis M, et al. MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG. Nat Chem Biol. 2018;14:1032-1042 pubmed 出版商

Broustas C, Hopkins K, Panigrahi S, Wang L, Virk R, Lieberman H. RAD9A promotes metastatic phenotypes through transcriptional regulation of anterior gradient 2 (AGR2). Carcinogenesis. 2019;40:164-172 pubmed 出版商

Bono S, Dello Sbarba P, Lulli M. Sensitivity to imatinib of KCL22 chronic myeloid leukemia cell survival/growth and stem cell potential under glucose shortage. Data Brief. 2018;20:1901-1904 pubmed 出版商

Soeda S, Yamada Nomoto K, Michiue T, Ohsugi M. RSK-MASTL Pathway Delays Meiotic Exit in Mouse Zygotes to Ensure Paternal Chromosome Stability. Dev Cell. 2018;47:363-376.e5 pubmed 出版商

Harms F, Kloth K, Bley A, Denecke J, Santer R, Lessel D, et al. Activating Mutations in PAK1, Encoding p21-Activated Kinase 1, Cause a Neurodevelopmental Disorder. Am J Hum Genet. 2018;103:579-591 pubmed 出版商

Georgess D, Spuul P, Le Clainche C, Le Nihouannen D, Fremaux I, Dakhli T, et al. Anti-osteoclastic effects of C-glucosidic ellagitannins mediated by actin perturbation. Eur J Cell Biol. 2018;97:533-545 pubmed 出版商

Zhu L, Kandasamy S, Liao S, Fukunaga R. LOTUS domain protein MARF1 binds CCR4-NOT deadenylase complex to post-transcriptionally regulate gene expression in oocytes. Nat Commun. 2018;9:4031 pubmed 出版商

Piwowarczyk K, Kwiecień E, Sośniak J, Zimoląg E, Guzik E, Sroka J, et al. Fenofibrate Interferes with the Diapedesis of Lung Adenocarcinoma Cells through the Interference with Cx43/EGF-Dependent Intercellular Signaling. Cancers (Basel). 2018;10: pubmed 出版商

Salami J, Alabi S, Willard R, Vitale N, Wang J, Dong H, et al. Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance. Commun Biol. 2018;1:100 pubmed 出版商

Baltussen L, Negraes P, Silvestre M, Claxton S, Moeskops M, Christodoulou E, et al. Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics. EMBO J. 2018;37: pubmed 出版商

Davies A, Itzhak D, Edgar J, Archuleta T, Hirst J, Jackson L, et al. AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A. Nat Commun. 2018;9:3958 pubmed 出版商

Kistler K, Trcek T, Hurd T, Chen R, Liang F, Sall J, et al. Phase transitioned nuclear Oskar promotes cell division of Drosophila primordial germ cells. elife. 2018;7: pubmed 出版商

Saunders J, Hore Z, Gentry C, McMahon S, Denk F. Negative Evidence for a Functional Role of Neuronal DNMT3a in Persistent Pain. Front Mol Neurosci. 2018;11:332 pubmed 出版商

Hou W, Cruz Cosme R, Wen F, Ahn J, Reeves I, Luo M, et al. Expression of Human Cytomegalovirus IE1 Leads to Accumulation of Mono-SUMOylated PML That Is Protected from Degradation by Herpes Simplex Virus 1 ICP0. J Virol. 2018;92: pubmed 出版商

Monda J, Cheeseman I. Dynamic regulation of dynein localization revealed by small molecule inhibitors of ubiquitination enzymes. Open Biol. 2018;8: pubmed 出版商

Boese C, Nye J, Buster D, McLamarrah T, Byrnes A, Slep K, et al. Asterless is a Polo-like kinase 4 substrate that both activates and inhibits kinase activity depending on its phosphorylation state. Mol Biol Cell. 2018;29:2874-2886 pubmed 出版商

Taraborrelli L, Peltzer N, Montinaro A, Kupka S, Rieser E, Hartwig T, et al. LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L. Nat Commun. 2018;9:3910 pubmed 出版商

Bacman S, Kauppila J, Pereira C, Nissanka N, Miranda M, Pinto M, et al. MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation. Nat Med. 2018;24:1696-1700 pubmed 出版商

Fort L, Batista J, Thomason P, Spence H, Whitelaw J, Tweedy L, et al. Fam49/CYRI interacts with Rac1 and locally suppresses protrusions. Nat Cell Biol. 2018;20:1159-1171 pubmed 出版商

Faktorová D, Bär A, Hashimi H, McKenney K, Horak A, Schnaufer A, et al. TbUTP10, a protein involved in early stages of pre-18S rRNA processing in Trypanosoma brucei. Mol Biochem Parasitol. 2018;225:84-93 pubmed 出版商

Staufer O, Hernandez B J, Rustom A. Protease-resistant cell meshworks: An indication of membrane nanotube-based syncytia formation. Exp Cell Res. 2018;372:85-91 pubmed 出版商

Kikuchi K, Ihara D, Fukuchi M, Tanabe H, Ishibashi Y, Tsujii J, et al. Involvement of SRF coactivator MKL2 in BDNF-mediated activation of the synaptic activity-responsive element in the Arc gene. J Neurochem. 2019;148:204-218 pubmed 出版商

Prasad H, Dang D, Kondapalli K, Natarajan N, Cebotaru V, Rao R. NHA2 promotes cyst development in an in vitro model of polycystic kidney disease. J Physiol. 2019;597:499-519 pubmed 出版商

Arai T, Tanaka M, Goda N. HIF-1-dependent lipin1 induction prevents excessive lipid accumulation in choline-deficient diet-induced fatty liver. Sci Rep. 2018;8:14230 pubmed 出版商

Jiang C, Wang X, Li X, Inlora J, Wang T, Liu Q, et al. Dynamic Human Environmental Exposome Revealed by Longitudinal Personal Monitoring. Cell. 2018;175:277-291.e31 pubmed 出版商

Yoneyama Y, Inamitsu T, Chida K, Iemura S, Natsume T, Maeda T, et al. Serine Phosphorylation by mTORC1 Promotes IRS-1 Degradation through SCF?-TRCP E3 Ubiquitin Ligase. iScience. 2018;5:1-18 pubmed 出版商

Jin H, Choi S, Kang M, Yun S, Kwon D, Noh Y, et al. Salicylic acid-induced transcriptional reprogramming by the HAC-NPR1-TGA histone acetyltransferase complex in Arabidopsis. Nucleic Acids Res. 2018;46:11712-11725 pubmed 出版商

Kučírková T, Stiborek M, Dúcka M, Navrátilová J, Bogdanović Pristov J, Popovic Bijelic A, et al. Anti-cancer effects of wedelolactone: interactions with copper and subcellular localization. Metallomics. 2018;10:1524-1531 pubmed 出版商

Paez Mayorga J, Chen A, Kotla S, Tao Y, Abe R, He E, et al. Ponatinib Activates an Inflammatory Response in Endothelial Cells via ERK5 SUMOylation. Front Cardiovasc Med. 2018;5:125 pubmed 出版商

Román García S, Merino Cortes S, Gardeta S, de Bruijn M, Hendriks R, Carrasco Y. Distinct Roles for Bruton's Tyrosine Kinase in B Cell Immune Synapse Formation. Front Immunol. 2018;9:2027 pubmed 出版商

Lu G, Weng S, Matyskiela M, Zheng X, Fang W, Wood S, et al. UBE2G1 governs the destruction of cereblon neomorphic substrates. elife. 2018;7: pubmed 出版商

Morini R, Ferrara S, Perrucci F, Zambetti S, Pelucchi S, Marcello E, et al. Lack of the Actin Capping Protein, Eps8, Affects NMDA-Type Glutamate Receptor Function and Composition. Front Mol Neurosci. 2018;11:313 pubmed 出版商

Arbel Rubinstein T, Shahmoon S, Zigmond E, Etan T, Merenbakh Lamin K, Pasmanik Chor M, et al. Klotho suppresses colorectal cancer through modulation of the unfolded protein response. Oncogene. 2019;38:794-807 pubmed 出版商

Ahmad M, Kroll T, Jakob J, Rauch A, Ploubidou A, Tuckermann J. Cell-based RNAi screening and high-content analysis in primary calvarian osteoblasts applied to identification of osteoblast differentiation regulators. Sci Rep. 2018;8:14045 pubmed 出版商

Jimeno S, Camarillo R, Mejías Navarro F, Fernández Ávila M, Soria Bretones I, Prados Carvajal R, et al. The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures. Cell Rep. 2018;24:3262-3273.e4 pubmed 出版商

Kim M, Park J, Lee E, Kim S, Shin S, Ahn J, et al. C16‑ceramide and sphingosine 1‑phosphate/S1PR2 have opposite effects on cell growth through mTOR signaling pathway regulation. Oncol Rep. 2018;40:2977-2987 pubmed 出版商

Gennaro V, Stanek T, Peck A, Sun Y, Wang F, Qie S, et al. Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells. Proc Natl Acad Sci U S A. 2018;115:E9298-E9307 pubmed 出版商

Nakanishi N, Martindale M. CRISPR knockouts reveal an endogenous role for ancient neuropeptides in regulating developmental timing in a sea anemone. elife. 2018;7: pubmed 出版商

Li J, Liu B, Song Y, Chen X. Cyclin A2 regulates symmetrical mitotic spindle formation and centrosome amplification in human colon cancer cells. Am J Transl Res. 2018;10:2669-2676 pubmed

Son S, Park S, Lee H, Siddiqi F, Lee J, Menzies F, et al. Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A. Cell Metab. 2019;29:192-201.e7 pubmed 出版商

Takeshima H, Horie M, Mikami Y, Makita K, Miyashita N, Matsuzaki H, et al. CISH is a negative regulator of IL-13-induced CCL26 production in lung fibroblasts. Allergol Int. 2019;68:101-109 pubmed 出版商

Killackey S, Rahman M, Soares F, Zhang A, Abdel Nour M, Philpott D, et al. The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1. Mol Cell Biochem. 2019;453:187-196 pubmed 出版商

Negoita F, Blomdahl J, Wasserstrom S, Winberg M, Osmark P, Larsson S, et al. PNPLA3 variant M148 causes resistance to starvation-mediated lipid droplet autophagy in human hepatocytes. J Cell Biochem. 2019;120:343-356 pubmed 出版商

Lopez Coral A, Striz A, Tuma P. A Serine/Threonine Kinase 16-Based Phospho-Proteomics Screen Identifies WD Repeat Protein-1 As A Regulator Of Constitutive Secretion. Sci Rep. 2018;8:13049 pubmed 出版商

Møller A, Füchtbauer E, Brüel A, Andersen T, Borggaard X, Pavlos N, et al. Septins are critical regulators of osteoclastic bone resorption. Sci Rep. 2018;8:13016 pubmed 出版商

Chen H, Fang Y, Wu J, Chen H, Zou Z, Zhang X, et al. RIPK3-MLKL-mediated necroinflammation contributes to AKI progression to CKD. Cell Death Dis. 2018;9:878 pubmed 出版商

Tuo Q, Liuyang Z, Lei P, Yan X, Shentu Y, Liang J, et al. Zinc induces CDK5 activation and neuronal death through CDK5-Tyr15 phosphorylation in ischemic stroke. Cell Death Dis. 2018;9:870 pubmed 出版商

Sasi N, Coquel F, Lin Y, Mackeigan J, Pasero P, Weinreich M. DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling. Neoplasia. 2018;20:985-995 pubmed 出版商

Agarwal S, Smith K, Zhou Y, Suzuki A, McKenney R, Varma D. Cdt1 stabilizes kinetochore-microtubule attachments via an Aurora B kinase-dependent mechanism. J Cell Biol. 2018;217:3446-3463 pubmed 出版商