产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
FLUKA, Sigma-Aldrich, Roche Applied Science
产品类型 :
抗体
产品名称 :
单克隆抗KRAS在小鼠生产的抗体
目录 :
WH0003845M1
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
3B10-2F2
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学
更多信息或购买 :
文章摘录数: 44
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:500; 图 s8e
Castel P, Cheng A, Cuevas Navarro A, Everman D, Papageorge A, Simanshu D, et al. RIT1 oncoproteins escape LZTR1-mediated proteolysis. Science. 2019;363:1226-1230 pubmed 出版商
  • 免疫细胞化学; 人类; 表 1
  • 酶联免疫吸附测定; 人类; 表 1
  • 免疫印迹; 人类; 图 1d
Waters A, Ozkan Dagliyan I, Vaseva A, Fer N, Strathern L, Hobbs G, et al. Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies. Sci Signal. 2017;10: pubmed 出版商
  • 免疫印迹; 人类; 1:100; 图 1
  • 免疫印迹; 小鼠; 1:100; 图 s3
White Y, Bagchi A, Van Ziffle J, Inguva A, Bollag G, Zhang C, et al. KRAS insertion mutations are oncogenic and exhibit distinct functional properties. Nat Commun. 2016;7:10647 pubmed 出版商
  • 免疫印迹; 人类
Newman A, Scholefield C, Kemp A, Newman M, McIver E, Kamal A, et al. TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling. PLoS ONE. 2012;7:e50672 pubmed 出版商
Amendola C, Mahaffey J, Parker S, Ahearn I, Chen W, Zhou M, et al. KRAS4A directly regulates hexokinase 1. Nature. 2019;576:482-486 pubmed 出版商
Blake D, Vaseva A, Hodge R, Kline M, Gilbert T, Tyagi V, et al. Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer. Sci Signal. 2019;12: pubmed 出版商
Wang M, Fer N, Galeas J, Collisson E, Kim S, Sharib J, et al. Blockade of leukemia inhibitory factor as a therapeutic approach to KRAS driven pancreatic cancer. Nat Commun. 2019;10:3055 pubmed 出版商
Guinn M, BALAZSI G. Noise-reducing optogenetic negative-feedback gene circuits in human cells. Nucleic Acids Res. 2019;: pubmed 出版商
Nkembo A, Amissah F, Ntantie E, Poku R, Salako O, Ikpatt O, et al. Polyisoprenylated Cysteinyl Amide Inhibitors Deplete K-Ras and Induce Caspase-dependent Apoptosis in Lung Cancer Cells. Curr Cancer Drug Targets. 2019;19:838-851 pubmed 出版商
Haghighi F, Dahlmann J, Nakhaei Rad S, Lang A, Kutschka I, Zenker M, et al. bFGF-mediated pluripotency maintenance in human induced pluripotent stem cells is associated with NRAS-MAPK signaling. Cell Commun Signal. 2018;16:96 pubmed 出版商
Ferino A, Miglietta G, Picco R, Vogel S, Wengel J, Xodo L. MicroRNA therapeutics: design of single-stranded miR-216b mimics to target KRAS in pancreatic cancer cells. RNA Biol. 2018;15:1273-1285 pubmed 出版商
Kam C, Dubash A, Magistrati E, Polo S, Satchell K, Sheikh F, et al. Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43. J Cell Biol. 2018;217:3219-3235 pubmed 出版商
Waters A, Bagni R, Portugal F, Hartley J. Single Synonymous Mutations in KRAS Cause Transformed Phenotypes in NIH3T3 Cells. PLoS ONE. 2016;11:e0163272 pubmed 出版商
Lim Y, Bacchiocchi A, Qiu J, Straub R, Bruckner A, Bercovitch L, et al. GNA14 Somatic Mutation Causes Congenital and Sporadic Vascular Tumors by MAPK Activation. Am J Hum Genet. 2016;99:443-50 pubmed 出版商
Manchado E, Weissmueller S, Morris J, Chen C, Wullenkord R, Lujambio A, et al. A combinatorial strategy for treating KRAS-mutant lung cancer. Nature. 2016;534:647-51 pubmed
Bukong T, Kodys K, Szabo G. A Novel Human Radixin Peptide Inhibits Hepatitis C Virus Infection at the Level of Cell Entry. Int J Pept Res Ther. 2014;20:269-276 pubmed
Jiao F, Hu H, Yuan C, Wang L, Jiang W, Jin Z, et al. Elevated expression level of long noncoding RNA MALAT-1 facilitates cell growth, migration and invasion in pancreatic cancer. Oncol Rep. 2014;32:2485-92 pubmed 出版商
van der Ent W, Burrello C, Teunisse A, Ksander B, van der Velden P, Jager M, et al. Modeling of human uveal melanoma in zebrafish xenograft embryos. Invest Ophthalmol Vis Sci. 2014;55:6612-22 pubmed 出版商
Foster J, Wu W, Scott S, Bassi M, Mohan D, Daoud Y, et al. Transforming growth factor β and insulin signal changes in stromal fibroblasts of individual keratoconus patients. PLoS ONE. 2014;9:e106556 pubmed 出版商
Li Z, Jiang J, Kong W. Berberine up-regulates hepatic low-density lipoprotein receptor through Ras-independent but AMP-activated protein kinase-dependent Raf-1 activation. Biol Pharm Bull. 2014;37:1766-75 pubmed
Kweon K, Lee C, Jung S, Ban E, Kang S, Jeong J, et al. Sirt1 induction confers resistance to etoposide-induced genotoxic apoptosis in thyroid cancers. Int J Oncol. 2014;45:2065-75 pubmed 出版商
Carver J, Dexheimer T, Hsu D, Weng M, Smith J, Guha R, et al. A high-throughput assay for small molecule destabilizers of the KRAS oncoprotein. PLoS ONE. 2014;9:e103836 pubmed 出版商
Jiang X, Yu X, Fan J, Guo L, Zhu C, Jiang W, et al. RFT2 is overexpressed in esophageal squamous cell carcinoma and promotes tumorigenesis by sustaining cell proliferation and protecting against cell death. Cancer Lett. 2014;353:78-86 pubmed 出版商
Aini W, Miyagawa Hayashino A, Ozeki M, Adeeb S, Hirata M, Tamaki K, et al. Accelerated telomere reduction and hepatocyte senescence in tolerated human liver allografts. Transpl Immunol. 2014;31:55-9 pubmed 出版商
van der Ent W, Jochemsen A, Teunisse A, Krens S, Szuhai K, Spaink H, et al. Ewing sarcoma inhibition by disruption of EWSR1-FLI1 transcriptional activity and reactivation of p53. J Pathol. 2014;233:415-24 pubmed 出版商
Vander Griend D, Litvinov I, Isaacs J. Conversion of androgen receptor signaling from a growth suppressor in normal prostate epithelial cells to an oncogene in prostate cancer cells involves a gain of function in c-Myc regulation. Int J Biol Sci. 2014;10:627-42 pubmed 出版商
Lai P, Hsu C, Wang S, Lee J, Tseng M, Hwang J, et al. Production of a neutralizing antibody against envelope protein of dengue virus type 2 using the linear array epitope technique. J Gen Virol. 2014;95:2155-2165 pubmed 出版商
Kim J, Jayaprakasha G, Patil B. Obacunone exhibits anti-proliferative and anti-aromatase activity in vitro by inhibiting the p38 MAPK signaling pathway in MCF-7 human breast adenocarcinoma cells. Biochimie. 2014;105:36-44 pubmed 出版商
Yeh C, Yen C, Chen Y, Cheng C, Huang S, Chang T, et al. Identification of aurora kinase A as an unfavorable prognostic factor and potential treatment target for metastatic gastrointestinal stromal tumors. Oncotarget. 2014;5:4071-86 pubmed
Iqbal N, Xu L, Devitt C, Skapek S. Isolation and characterization of mammalian cells expressing the Arf promoter during eye development. Biotechniques. 2014;56:239-49 pubmed 出版商
Brown D, LASSEGUE B, Lee M, Zafari R, Long J, Saavedra H, et al. Poldip2 knockout results in perinatal lethality, reduced cellular growth and increased autophagy of mouse embryonic fibroblasts. PLoS ONE. 2014;9:e96657 pubmed 出版商
Cortez M, Valdecanas D, Zhang X, Zhan Y, Bhardwaj V, Calin G, et al. Therapeutic delivery of miR-200c enhances radiosensitivity in lung cancer. Mol Ther. 2014;22:1494-1503 pubmed 出版商
Boufraqech M, Zhang L, Jain M, Patel D, Ellis R, Xiong Y, et al. miR-145 suppresses thyroid cancer growth and metastasis and targets AKT3. Endocr Relat Cancer. 2014;21:517-31 pubmed 出版商
Bohanon F, Wang X, Ding C, Ding Y, Radhakrishnan G, Rastellini C, et al. Oridonin inhibits hepatic stellate cell proliferation and fibrogenesis. J Surg Res. 2014;190:55-63 pubmed 出版商
Wan J, Benkdane M, Alons E, Lotersztajn S, Pavoine C. M2 kupffer cells promote hepatocyte senescence: an IL-6-dependent protective mechanism against alcoholic liver disease. Am J Pathol. 2014;184:1763-72 pubmed 出版商
Song J, Zheng B, Bu X, Fei Y, Shi S. Negative association of R-Ras activation and breast cancer development. Oncol Rep. 2014;31:2776-84 pubmed 出版商
Yang H, Xu W, Li Y, Lan P, Zhang J, Zhang Y, et al. Superior activity of a new histone deacetylase inhibitor (ZYJ-34c) in inhibiting growth of human leukemia cells by inducing p21WAF1 expression and cell cycle arrest. Anticancer Drugs. 2014;25:767-77 pubmed 出版商
Wu X, Qi X, Liang M, Li C, Cardona C, Li D, et al. Roles of viroplasm-like structures formed by nonstructural protein NSs in infection with severe fever with thrombocytopenia syndrome virus. FASEB J. 2014;28:2504-16 pubmed 出版商
Sakai H, Fujigaki H, Mazur S, Appella E. Wild-type p53-induced phosphatase 1 (Wip1) forestalls cellular premature senescence at physiological oxygen levels by regulating DNA damage response signaling during DNA replication. Cell Cycle. 2014;13:1015-29 pubmed 出版商
Toulany M, Minjgee M, Saki M, Holler M, Meier F, Eicheler W, et al. ERK2-dependent reactivation of Akt mediates the limited response of tumor cells with constitutive K-RAS activity to PI3K inhibition. Cancer Biol Ther. 2014;15:317-28 pubmed 出版商
He Q, Huang Y, Cai L, Zhang S, Zhang C. Expression and prognostic value of Ars2 in hepatocellular carcinoma. Int J Clin Oncol. 2014;19:880-8 pubmed 出版商
Chen J, Bi H, Hou J, Zhang X, Zhang C, Yue L, et al. Atorvastatin overcomes gefitinib resistance in KRAS mutant human non-small cell lung carcinoma cells. Cell Death Dis. 2013;4:e814 pubmed 出版商
Chew T, Liu X, Liu L, Spitsbergen J, Gong Z, Low B. Crosstalk of Ras and Rho: activation of RhoA abates Kras-induced liver tumorigenesis in transgenic zebrafish models. Oncogene. 2014;33:2717-27 pubmed 出版商
Puebla Osorio N, Kim J, Ojeda S, Zhang H, Tavana O, Li S, et al. A novel Ku70 function in colorectal homeostasis separate from nonhomologous end joining. Oncogene. 2014;33:2748-57 pubmed 出版商
产品信息
Product No. :
WH0003845M1
产品名称 :
单克隆抗KRAS在小鼠生产的抗体
宿主 :
小鼠
共轭标签 :
未共轭
抗体类型 :
单克隆
Clone Number (if monoclonal) :
3B10-2F2
应用/描述 :
Suitable for ELISA; western blot: 1-5 μg/mL; immunofluorescence; capture ELISA
物种活性 :
人类
抗体亚型 :
IgG1κ
储存 :
存放在-20°C
更多信息或购买 :
公司信息
西格玛奥德里奇
上海市徐汇区淮海中路1010号嘉华中心41楼
techservCN@sial.com
http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
公司总部: 美国
Sigma-Aldrich是一家在生命科学领域领先的且拥有高科技产品的公司,致力于为生命科学、制药化工等领域提供高质量的服务和产品。