产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
FLUKA, Sigma-Aldrich, Roche Applied Science
产品类型 :
抗体
产品名称 :
单克隆抗YAP1在小鼠生产的抗体
目录 :
WH0010413M1
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2F12
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫印迹基因敲除验证, 免疫细胞化学基因敲除验证
更多信息或购买 :
文章摘录数: 22
出版应用/物种/样本/稀释参考文献
  • 免疫沉淀; 小鼠; 图 3e
Rojek K, Krzemien J, Dolezyczek H, Boguszewski P, Kaczmarek L, Konopka W, et al. Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice. PLoS Biol. 2019;17:e3000253 pubmed 出版商
  • 免疫细胞化学基因敲除验证; 小鼠; 1:200; 图 2a
  • 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 3f
Huang Z, Hu J, Pan J, Wang Y, Hu G, Zhou J, et al. YAP stabilizes SMAD1 and promotes BMP2-induced neocortical astrocytic differentiation. Development. 2016;143:2398-409 pubmed 出版商
  • 免疫组化; 人类; 图 6
  • 免疫组化; 小鼠; 图 4
Nishio M, Sugimachi K, Goto H, Wang J, Morikawa T, Miyachi Y, et al. Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice. Proc Natl Acad Sci U S A. 2016;113:E71-80 pubmed 出版商
Xu X, Shen X, Feng W, Yang D, Jin L, Wang J, et al. D-galactose induces senescence of glioblastoma cells through YAP-CDK6 pathway. Aging (Albany NY). 2020;12:18501-18521 pubmed 出版商
Wen T, Liu J, He X, Dong K, Hu G, Yu L, et al. Transcription factor TEAD1 is essential for vascular development by promoting vascular smooth muscle differentiation. Cell Death Differ. 2019;: pubmed 出版商
Kim W, Cho Y, Wang X, Park O, Ma X, Kim H, et al. Hippo signaling is intrinsically regulated during cell cycle progression by APC/CCdh1. Proc Natl Acad Sci U S A. 2019;116:9423-9432 pubmed 出版商
Tian L, Ye Z, Kafka K, Stewart D, Anders R, Schwarz K, et al. Biliary Atresia Relevant Human Induced Pluripotent Stem Cells Recapitulate Key Disease Features in a Dish. J Pediatr Gastroenterol Nutr. 2019;68:56-63 pubmed 出版商
Pan J, Xiong L, Zhao K, Zeng P, Wang B, Tang F, et al. YAP promotes osteogenesis and suppresses adipogenic differentiation by regulating β-catenin signaling. Bone Res. 2018;6:18 pubmed 出版商
Stammnitz M, Coorens T, Gori K, Hayes D, Fu B, Wang J, et al. The Origins and Vulnerabilities of Two Transmissible Cancers in Tasmanian Devils. Cancer Cell. 2018;33:607-619.e15 pubmed 出版商
Goto H, Nishio M, To Y, Oishi T, Miyachi Y, Maehama T, et al. Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEAD-dependent repression of SOX9. Development. 2018;145: pubmed 出版商
Wen T, Yin Q, Yu L, Hu G, Liu J, Zhang W, et al. Characterization of mice carrying a conditional TEAD1 allele. Genesis. 2017;55: pubmed 出版商
Zhao K, Shen C, Lu Y, Huang Z, Li L, Rand C, et al. Muscle Yap Is a Regulator of Neuromuscular Junction Formation and Regeneration. J Neurosci. 2017;37:3465-3477 pubmed 出版商
Zhang P, Wang S, Wang S, Qiao J, Zhang L, Zhang Z, et al. Dual function of partitioning-defective 3 in the regulation of YAP phosphorylation and activation. Cell Discov. 2016;2:16021 pubmed 出版商
Xu F, Ahmed A, Kang X, Hu G, Liu F, Zhang W, et al. MicroRNA-15b/16 Attenuates Vascular Neointima Formation by Promoting the Contractile Phenotype of Vascular Smooth Muscle Through Targeting YAP. Arterioscler Thromb Vasc Biol. 2015;35:2145-52 pubmed 出版商
Li M, Lu J, Zhang F, Li H, Zhang B, Wu X, et al. Yes-associated protein 1 (YAP1) promotes human gallbladder tumor growth via activation of the AXL/MAPK pathway. Cancer Lett. 2014;355:201-9 pubmed 出版商
Jerhammar F, Johansson A, Ceder R, Welander J, Jansson A, Grafström R, et al. YAP1 is a potential biomarker for cetuximab resistance in head and neck cancer. Oral Oncol. 2014;50:832-9 pubmed 出版商
Tsujiura M, Mazack V, Sudol M, Kaspar H, Nash J, Carey D, et al. Yes-associated protein (YAP) modulates oncogenic features and radiation sensitivity in endometrial cancer. PLoS ONE. 2014;9:e100974 pubmed 出版商
Lavado A, He Y, Pare J, Neale G, Olson E, Giovannini M, et al. Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013;140:3323-34 pubmed 出版商
Zhang N, Bai H, David K, Dong J, Zheng Y, Cai J, et al. The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. Dev Cell. 2010;19:27-38 pubmed 出版商
Camargo F, Gokhale S, Johnnidis J, Fu D, Bell G, Jaenisch R, et al. YAP1 increases organ size and expands undifferentiated progenitor cells. Curr Biol. 2007;17:2054-60 pubmed
Levy D, Adamovich Y, Reuven N, Shaul Y. The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73. Cell Death Differ. 2007;14:743-51 pubmed
Komuro A, Nagai M, Navin N, Sudol M. WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. J Biol Chem. 2003;278:33334-41 pubmed
产品信息
Product No. :
WH0010413M1
产品名称 :
单克隆抗YAP1在小鼠生产的抗体
宿主 :
小鼠
共轭标签 :
未共轭
抗体类型 :
单克隆
Clone Number (if monoclonal) :
2F12
应用/描述 :
Suitable for ELISA; western blot: 1-5 μg/mL; immunohistochemistry (formalin-fixed, paraffin-embedded sections); immunofluorescence
物种活性 :
人类
抗体亚型 :
IgG2aκ
储存 :
存放在-20°C
更多信息或购买 :
公司信息
西格玛奥德里奇
上海市徐汇区淮海中路1010号嘉华中心41楼
techservCN@sial.com
http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
公司总部: 美国
Sigma-Aldrich是一家在生命科学领域领先的且拥有高科技产品的公司,致力于为生命科学、制药化工等领域提供高质量的服务和产品。