抗体

兔ACTR3抗体

MBS001425

0.05毫升

270美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定, 酶免疫法

抗体

兔ACTR3抗体

ACTR3

actin-related protein 3 isoform 1; Actin-related protein 3; actin-related protein 3; actin-like protein 3; ARP3 actin-related protein 3 homolog (yeast); Actin-like protein 3

ACTR3

ACTR3;ACTR3;ARP3;ARP3

ARP3_HUMAN

兔

人类, 小鼠, 大鼠

418

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

1毫克/毫升

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)

5031573

NP_005712.1

NM_005721.4

P61158

47,371 Da

B Cell Receptor Signaling Pathway 198909!!CDC42 Signaling Events Pathway 137994!!ErbB1 Downstream Signaling Pathway 138057!!Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway 771577!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!RAC1 Signaling Pathway 169355!!Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway 771579

The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]

Function: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis. Ref.7 Ref.14. Subunit structure: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with WHDC1. Ref.1 Ref.7 Ref.12. Subcellular location: Cytoplasm cytoskeleton. Cell projection Ref.1 Ref.7. Sequence similarities: Belongs to the actin family. ARP3 subfamily.

0.05毫升

270美元