ELISA/assay

鱼类过氧化物酶体增殖物激活受体γ酶联免疫吸附试剂盒

MBS005886

48-Strip-Wells

470美元

酶联免疫吸附试剂盒

鱼类过氧化物酶体增殖物激活受体γ酶联免疫吸附试剂盒

[过氧化物酶体增殖物激活受体γ]

[peroxisome proliferator-activated receptor gamma isoform 1; Peroxisome proliferator-activated receptor gamma; peroxisome proliferator-activated receptor gamma; PPAR gamma; PPAR-gamma; nuclear receptor subfamily 1 group C member 3; peroxisome proliferator-activated receptor gamma 1; peroxisome proliferator-activated nuclear receptor gamma variant 1; peroxisome proliferator-activated receptor gamma; Nuclear receptor subfamily 1 group C member 3]

[PPARgamma]

[过氧化物酶体增生物激活受体gamma;过氧化物酶体增生物激活受体gamma;GLM1;CIMT1;NR1C3;PPARG1;PPARG2;PPARgamma;NR1C3;过氧化物酶体增殖物激活受体γ]

PPARG_HUMAN

Fish

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Rat Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of PPARD (hereafter termed "analyte") in undiluted original Rat serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

116284373

NP_619725.2

NM_138711.3

P37231

57,620 Da

Adipogenesis Pathway (198832); Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway (137993); Developmental Biology Pathway (477129); Energy Metabolism Pathway (198907); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Gene Expression Pathway (105937); Generic Transcription Pathway (105938); Huntington's Disease Pathway (83100); Huntington's Disease Pathway (512); Metabolism Pathway (477135)

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]

PPAR-gamma: a transcription factor, member of the nuclear hormone receptor superfamily. Receptor for hypolipidemic drugs and fatty acids. Preferentially expressed in adipocytes as well as in vascular smooth muscle cells and macrophage. Regulator of adipogenesis and lipid metabolism, modulates insulin sensitivity, cell proliferation and inflammation. Phosphorylated and inhibited by MAP kinase. Heterodimerizes with the retinoid X receptor. Interacts with NCOA6 coactivator, leading to a strong increase in transcription of target genes. Two splice-variant isoforms have been described. Protein type: Nuclear receptor; DNA-binding. Chromosomal Location of Human Ortholog: 3p25. Cellular Component: nucleoplasm; perinuclear region of cytoplasm; nucleus; cytosol. Molecular Function: ligand-dependent nuclear receptor activity; transcription activator binding; zinc ion binding; drug binding; alpha-actinin binding; protein phosphatase binding; retinoid X receptor binding; arachidonic acid binding; protein binding; enzyme binding; DNA binding; ligand-dependent nuclear receptor transcription coactivator activity; prostaglandin receptor activity; sequence-specific DNA binding; estrogen receptor binding; steroid hormone receptor activity; chromatin binding; transcription factor activity. Biological Process: negative regulation of smooth muscle cell proliferation; negative regulation of collagen biosynthetic process; heart development; positive regulation of transcription, DNA-dependent; low-density lipoprotein receptor biosynthetic process; cell maturation; rhythmic process; lipid homeostasis; negative regulation of transcription from RNA polymerase II promoter; response to lipid; glucose homeostasis; signal transduction; response to vitamin A; response to caffeine; epithelial cell differentiation; regulation of blood pressure; positive regulation of oligodendrocyte differentiation; response to nutrient; placenta development; long-chain fatty acid transport; caspase activation; transcription initiation from RNA polymerase II promoter; organ regeneration; response to retinoic acid; cell fate commitment; monocyte differentiation; negative regulation of acute inflammatory response; regulation of circadian rhythm; response to starvation; negative regulation of telomerase activity; G-protein coupled receptor protein signaling pathway; cellular response to insulin stimulus; lipoprotein transport; response to mechanical stimulus; response to estrogen stimulus; response to low density lipoprotein stimulus; positive regulation of fatty acid oxidation; white fat cell differentiation; brown fat cell differentiation; positive regulation of fat cell differentiation; innate immune response; positive regulation of transcription factor activity; fatty acid oxidation; gene expression; positive regulation of transcription from RNA polymerase II promoter; steroid hormone mediated signaling; response to cold; lipid metabolic process; negative regulation of cell growth; negative regulation of transcription, DNA-dependent; positive regulation of phagocytosis, engulfment. Disease: Obesity; Lipodystrophy, Familial Partial, Type 3; Carotid Intimal Medial Thickness 1; Diabetes Mellitus, Noninsulin-dependent

48-Strip-Wells

470美元

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095