ELISA/assay

仓鼠白细胞介素17A酶联免疫吸附试剂盒

MBS010012

48-Strip-Wells

435美元

酶联免疫吸附试剂盒

仓鼠白细胞介素17A酶联免疫吸附试剂盒

白细胞介素17A

白细胞介素17A;白细胞介素17A;白细胞介素17A;CTLA-8;细胞毒性T淋巴细胞 抗原8;细胞毒性T淋巴细胞 蛋白8;白细胞介素17(细胞毒性T淋巴细胞 丝氨酸酯酶8);白细胞介素17A;细胞毒性T淋巴细胞 抗原8

IL-17A

IL17A;IL17A;白细胞介素-17;CTLA8;IL-17;IL-17A;CTLA8;白细胞介素-17;IL-17;IL-17A;CTLA-8

IL17_HUMAN

仓鼠

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Undiluted original Hamster body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich. Detection Range: 3.12 pg/ml - 100 pg/ml. Sensitivity: 1.0 pg/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of IL17A (hereafter termed "analyte") in undiluted original Hamster body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

4504651

NP_002181.1

NM_002190.2

Q16552

17,504 Da

Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL23-mediated Signaling Events Pathway (138000); IL27-mediated Signaling Events Pathway (137929); Inflammatory Bowel Disease Pathway (842771); Rheumatoid Arthritis Pathway (200309); Rheumatoid Arthritis Pathway (200269); TCR Signaling Pathway (198862)

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]

IL17A: Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. Belongs to the IL-17 family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 6p12. Cellular Component: extracellular space; external side of plasma membrane. Molecular Function: cytokine activity. Biological Process: cell death; cell-cell signaling; positive regulation of osteoclast differentiation; positive regulation of interleukin-23 production; apoptosis; protein amino acid glycosylation; immune response; positive regulation of transcription from RNA polymerase II promoter; inflammatory response

48-Strip-Wells

435美元

96-Strip-Wells

600