产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
鸡水闸蛋白1酶联免疫吸附试剂盒
目录 :
MBS026451
规格 :
48-Strip-Wells
价格 :
470美元
更多信息或购买 :
产品信息
目录号 :
MBS026451
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
鸡水闸蛋白1酶联免疫吸附试剂盒
产品简称 :
[水闸蛋白1]
其他名称 :
[claudin-1; Claudin-1; claudin-1; senescence-associated epithelial membrane protein 1; claudin 1; Senescence-associated epithelial membrane protein]
产品基因名称 :
[CLDN1]
其他基因名称 :
[CLDN1;CLDN1;CLD1;SEMP1;ILVASC;CLD1;SEMP1]
UniProt数据库进入名 :
CLD1_HUMAN
反应物种 :
特异性 :
No significant cross-reactivity or interference between this analyte and analogues is observed.
储存稳定性 :
Store all reagents at 2-8 degree C
其它信息1 :
Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.25ng/ml-8ng/ml. Sensitivity: 0.1ng/ml.
其他信息2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
产品描述 :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of CLDN1 (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
NCBI GI登录号 :
10863887
NCBI登录号 :
NP_066924.1
NCBI基因登录号 :
NM_021101.4
UniProt数据库登录号 :
O95832
NCBI分子量 :
22,744 Da
NCBI信号通路 :
Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Junction Organization Pathway (160966); Cell-Cell Communication Pathway (477132); Cell-cell Junction Organization Pathway (119532); Hepatitis C Pathway (173973); Hepatitis C Pathway (173907); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494); Nectin Adhesion Pathway (138054)
NCBI总结 :
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
Claudin-1: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Acts as a co- receptor for HCV entry into hepatic cells. Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL. May interact with HCV E1 and E2 proteins. Strongly expressed in liver and kidney. Expressed in heart, brain, spleen, lung and testis. Belongs to the claudin family. Protein type: Membrane protein, multi-pass; Membrane protein, integral; Cytoskeletal. Chromosomal Location of Human Ortholog: 3q28-q29. Cellular Component: tight junction; integral to plasma membrane; apical plasma membrane; integral to membrane; lateral plasma membrane. Molecular Function: identical protein binding; protein binding; structural molecule activity. Biological Process: intercellular junction assembly and maintenance; viral reproduction; cell adhesion; calcium-independent cell-cell adhesion. Disease: Ichthyosis, Leukocyte Vacuoles, Alopecia, And Sclerosing Cholangitis
尺寸1 :
48-Strip-Wells
价格1 :
470美元
尺寸2 :
96-Strip-Wells
价格2 :
680
size3 :
5x96-Strip-Wells
价格3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。