产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
仓鼠白细胞介素13酶联免疫吸附试剂盒
目录 :
MBS033275
规格 :
48-Strip-Wells
价格 :
435美元
更多信息或购买 :
产品信息
目录号 :
MBS033275
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
仓鼠白细胞介素13酶联免疫吸附试剂盒
产品简称 :
白细胞介素13
其他名称 :
白细胞介素13;白细胞介素13;白细胞介素13;白细胞介素13
产品基因名称 :
IL-13
其他基因名称 :
白细胞介素-13;白细胞介素-13;P600;IL-13;NC30;IL-13
UniProt数据库进入名 :
IL13_HUMAN
反应物种 :
仓鼠
特异性 :
No significant cross-reactivity or interference between this analyte and analogues is observed.
储存稳定性 :
Store all reagents at 2-8 degree C
其它信息1 :
Samples: Undiluted original Hamster body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 6.25 pg/ml - 200 pg/ml. Sensitivity: 1.0 pg/ml.
其他信息2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
产品描述 :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of IL13 (hereafter termed "analyte") in undiluted original Hamster body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
NCBI GI登录号 :
26787978
NCBI登录号 :
NP_002179.2
NCBI基因登录号 :
NM_002188.2
UniProt数据库登录号 :
P35225
NCBI分子量 :
15,816 Da
NCBI信号通路 :
Asthma Pathway (83120); Asthma Pathway (532); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Cytokines And Inflammatory Response Pathway (198794); Fc Epsilon RI Signaling Pathway (83082); Fc Epsilon RI Signaling Pathway (493); Glucocorticoid Receptor Regulatory Network Pathway (138014); IL12 Signaling Mediated By STAT4 Pathway (137936); Inflammatory Bowel Disease Pathway (842771)
NCBI总结 :
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
IL13: Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH). Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure. Belongs to the IL-4/IL-13 family. Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 5q31. Cellular Component: extracellular space; cytoplasm; extracellular region; external side of plasma membrane. Molecular Function: protein binding; interleukin-13 receptor binding; cytokine activity. Biological Process: response to nicotine; positive regulation of smooth muscle cell proliferation; microglial cell activation; regulation of proton transport; response to lipopolysaccharide; signal transduction; positive regulation of connective tissue growth factor production; positive regulation of tyrosine phosphorylation of Stat6 protein; positive regulation of immunoglobulin production; response to ethanol; positive regulation of protein secretion; cell-cell signaling; positive regulation of B cell proliferation; immune response; positive regulation of release of sequestered calcium ion into cytosol; cell motility; inflammatory response; negative regulation of NAD(P)H oxidase activity; positive regulation of macrophage activation. Disease: Asthma, Susceptibility To; Allergic Rhinitis
尺寸1 :
48-Strip-Wells
价格1 :
435美元
尺寸2 :
96-Strip-Wells
价格2 :
600
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。