产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
人类血管内皮生长因子受体2酶联免疫吸附试剂盒
目录 :
MBS041074
规格 :
48-Strip-Wells
价格 :
435美元
更多信息或购买 :
产品信息
目录号 :
MBS041074
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
人类血管内皮生长因子受体2酶联免疫吸附试剂盒
产品简称 :
血管内皮生长因子受体2
其他名称 :
vascular endothelial growth factor receptor 2; Vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor 2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1
产品基因名称 :
VEGFR2
其他基因名称 :
激酶插入区受体;激酶插入区受体;FLK1;CD309;VEGFR;VEGFR2;FLK1;VEGFR2;VEGFR-2;FLK-1;激酶插入区受体
UniProt数据库进入名 :
VGFR2_HUMAN
反应物种 :
人类
储存稳定性 :
Store all reagents at 2-8 degree C
其它信息1 :
Assay Type: Sandwich
NCBI GI登录号 :
11321597
NCBI登录号 :
NP_002244.1
NCBI基因登录号 :
NM_002253.2
UniProt数据库登录号 :
P35968
NCBI分子量 :
151,527 Da
NCBI信号通路 :
Angiogenesis Pathway (198772); Cardiac Progenitor Differentiation Pathway (712094); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Endocytosis Pathway (102279); Endocytosis Pathway (102181); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); HIF-2-alpha Transcription Factor Network Pathway (137956)
NCBI总结 :
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
UniProt数据库总结 :
VEGFR2: a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2. Plays a key role in vascular development and regulation of vascular permeability. Protein type: Kinase, protein; Membrane protein, integral; EC 2.7.10.1; Protein kinase, tyrosine (receptor); Protein kinase, TK; TK group; VEGFR family. Chromosomal Location of Human Ortholog: 4q11-q12. Cellular Component: Golgi apparatus; endoplasmic reticulum; integral to plasma membrane; cytoplasmic membrane-bound vesicle; early endosome; extracellular region; plasma membrane; nucleus; cell junction; endosome; external side of plasma membrane; lipid raft. Molecular Function: integrin binding; vascular endothelial growth factor receptor activity; protein binding; protein-tyrosine kinase activity; growth factor binding; receptor signaling protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity; Hsp90 protein binding; ATP binding. Biological Process: extracellular matrix organization and biogenesis; peptidyl-tyrosine phosphorylation; positive regulation of positive chemotaxis; viral reproduction; protein amino acid autophosphorylation; cell maturation; calcium ion homeostasis; regulation of cell shape; positive regulation of MAPKKK cascade; ovarian follicle development; positive regulation of focal adhesion formation; positive regulation of mesenchymal cell proliferation; positive regulation of cell proliferation; angiogenesis; vasculogenesis; endothelial cell differentiation; cell fate commitment; embryonic hemopoiesis; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of angiogenesis; branching morphogenesis of a tube; cell migration during sprouting angiogenesis; positive regulation of endothelial cell proliferation; positive regulation of protein amino acid phosphorylation; vascular endothelial growth factor receptor signaling pathway; lymph vessel development; alveolus development; surfactant homeostasis; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of cell migration; negative regulation of apoptosis. Disease: Hemangioma, Capillary Infantile
尺寸1 :
48-Strip-Wells
价格1 :
435美元
尺寸2 :
96-Strip-Wells
价格2 :
600
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。