ELISA/assay

人类锚蛋白重复区域含蛋白1酶联免疫吸附试剂盒

MBS041175

48-Strip-Wells

435美元

酶联免疫吸附试剂盒

人类锚蛋白重复区域含蛋白1酶联免疫吸附试剂盒

锚蛋白重复区域含蛋白1

ankyrin repeat domain-containing protein 1; Ankyrin repeat domain-containing protein 1; ankyrin repeat domain-containing protein 1; liver ankyrin repeat domain 1; cardiac ankyrin repeat protein; cytokine-inducible nuclear protein; cytokine-inducible gene C-193 protein; ankyrin repeat domain 1 (cardiac muscle); Cardiac ankyrin repeat protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein

ANKRD1

ANKRD1;ANKRD1;ALRP;鲤鱼;C-193;CVARP;MCARP;bA320F15.2;C193;鲤鱼;HA1A2

ANKR1_HUMAN

人类

Store all reagents at 2-8 degree C

Assay Type: Sandwich

38327522

NP_055206.2

NM_014391.2

Q15327

36,252 Da

Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPARA Activates Gene Expression Pathway (530749); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544)

The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system. [provided by RefSeq, Jul 2008]

ANKRD1: May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. Defects in ANKRD1 may be a cause of total anomalous pulmonary venous return (TAPVR). TAPVR is a rare congenital heart disease (CHD) in which the pulmonary veins fail to connect to the left atrium during cardiac development, draining instead into either the right atrium or one of its venous tributaries. This disease accounts for 1.5% of all CHDs and has a prevalence of approximately 1 out of 15 000 live births. Protein type: Transcription factor. Chromosomal Location of Human Ortholog: 10q23.31. Cellular Component: nucleoplasm; I band; transcription factor complex; sarcomere; cytoplasm; nucleolus; cytosol; nucleus. Molecular Function: protein binding; DNA binding; p53 binding; histone deacetylase binding; titin binding; transcription corepressor activity. Biological Process: positive regulation of protein secretion; positive regulation of apoptosis; cardiac muscle morphogensis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of DNA damage response, signal transduction by p53 class mediator; cellular lipid metabolic process; negative regulation of transcription from RNA polymerase II promoter; sarcomere organization

48-Strip-Wells

435美元

96-Strip-Wells

600