产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
小鼠单克隆抗体抗人类BRF1
目录 :
MBS120050
规格 :
0.1毫克
价格 :
345美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
BRF1G2A8
反应物种 :
人类
应用 :
免疫细胞化学
更多信息或购买 :
产品信息
目录号 :
MBS120050
产品类型 :
抗体
产品全称 :
小鼠单克隆抗体抗人类BRF1
产品简称 :
BRF1
产品名称同义词 :
BRF1 homolog, subunit of RNA polymerase III? transcription initiation factor IIIB (S. cerevisiae) (BRF1); BRF; hBRF; GTF3B; TAF3C; TAF3B2; TF3B90;TAFIII90; TFIIIB90; MGC105048
其他名称 :
Homo sapiens BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit (BRF1), transcript variant 1, mRNA; Transcription factor IIIB 90 kDa subunit; transcription factor IIIB 90 kDa subunit; B - related factor 1; BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB; TATA box binding protein (TBP)-associated factor 3C; TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 2; TBP - associated factor, RNA polymerase III, 90kD; epididymis secretory sperm binding protein Li 76p; general transcription factor IIIB, 90kD subunit; BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit; B-related factor 1; BRF-1; hBRF; TAF3B2; TATA box-binding protein-associated factor, RNA polymerase III, subunit 2
产品基因名称 :
BRF1
其他基因名称 :
BRF1;BRF1;BRF;CFDS;hBRF;BRF-1;GTF3B;TAF3C;TAF3B2;TF3B90;TAFIII90;TFIIIB90;HEL-S-76p
UniProt数据库进入名 :
TF3B_HUMAN
克隆性 :
单克隆
抗体亚型 :
IgG1
克隆 :
BRF1G2A8
宿主 :
小鼠
反应物种 :
人类
序列长度 :
3677
浓度 :
100微克/毫升(1.0毫升)
检测过的应用 :
Dot Blot (DB), Immunocytochemistry (ICC)
其它信息1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
其他信息2 :
Sterility: Filtered through a 0.22 um membrane.
产品描述 :
This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Three alternatively spliced variants encoding three different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. A transcript encoding a fourth isoform has not yet been completely characterized. [NCBI Entrez Gene Summary]
NCBI GI登录号 :
338753403
NCBI登录号 :
NP_001510.2
NCBI基因登录号 :
NM_001519
NCBI分子量 :
47,978 Da
NCBI信号通路 :
Gene Expression Pathway (105937); Integrated Pancreatic Cancer Pathway (711360); RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway (160948); RNA Polymerase III Abortive And Retractive Initiation Pathway (160949); RNA Polymerase III Transcription Pathway (106561); RNA Polymerase III Transcription Initiation Pathway (106562); RNA Polymerase III Transcription Initiation From Type 1 Promoter Pathway (106563); RNA Polymerase III Transcription Initiation From Type 2 Promoter Pathway (106564)
NCBI总结 :
This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Several alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. [provided by RefSeq, Jun 2011]
UniProt数据库总结 :
GTF3B: General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter. Belongs to the TFIIB family. 7 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription initiation complex. Chromosomal Location of Human Ortholog: 14q. Cellular Component: nucleoplasm; transcription factor TFIIIB complex. Molecular Function: zinc ion binding; TATA-binding protein binding. Biological Process: transcription from RNA polymerase III promoter; transcription initiation from RNA polymerase III promoter; tRNA transcription; regulation of transcription, DNA-dependent; gene expression; regulation of mRNA stability; rRNA transcription. Disease: Cerebellofaciodental Syndrome
尺寸1 :
0.1毫克
价格1 :
345美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。