产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
小鼠单克隆抗体抗人类CHTF18
目录 :
MBS120149
规格 :
0.1毫克
价格 :
345美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2182C3a
反应物种 :
人类
应用 :
免疫印迹, 免疫沉淀
更多信息或购买 :
产品信息
目录号 :
MBS120149
产品类型 :
抗体
产品全称 :
小鼠单克隆抗体抗人类CHTF18
产品简称 :
CHTF18
产品名称同义词 :
Homo sapiens CTF18, chromosome transmission fidelity factor 18?homolog (S. cerevisiae) (CHTF18); CHL12; Ctf18; RUVBL;C16orf41; C321D2.2; C321D2.3; C321D2.4
其他名称 :
Homo sapiens CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) (CHTF18), mRNA; Chromosome transmission fidelity protein 18 homolog; chromosome transmission fidelity protein 18 homolog; C321D2.3 (novel protein); C321D2.4 (novel protein); hCTF18; homolog of yeast CHL12; some homology with holliday junction DNA helicase RUVB like; CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae); CHL12
产品基因名称 :
CHTF18
其他基因名称 :
CHTF18;CHTF18;CHL12;Ctf18;RUVBL;C16orf41;C321D2.2;C321D2.3;C321D2.4
UniProt数据库进入名 :
CTF18_HUMAN
克隆性 :
单克隆
抗体亚型 :
IgG1
克隆 :
2182C3a
宿主 :
小鼠
反应物种 :
人类
序列长度 :
3096
浓度 :
100微克/毫升(1.0毫升)
检测过的应用 :
Dot Blot (DB), Immunoprecipitation (IP), Western Blot (WB)
其它信息1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
其他信息2 :
Sterility: Filtered through a 0.22 um membrane.
NCBI GI登录号 :
157951660
NCBI登录号 :
NP_071375.1
NCBI基因登录号 :
NM_022092
NCBI分子量 :
61,869 Da
NCBI信号通路 :
Gastric Cancer Network 2 Pathway (760637)
NCBI总结 :
CHTF18, CHTF8 (MIM 613202), and DCC1 (DSCC1; MIM 613203) are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]).[supplied by OMIM, Dec 2009]
UniProt数据库总结 :
CTF18: Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single- stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18- RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH. Belongs to the activator 1 small subunits family. CTF18 subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: DNA replication. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: nucleoplasm; membrane; cytoplasm. Molecular Function: DNA binding; ATP binding. Biological Process: negative regulation of chromosome segregation; meiotic recombination; spermatogenesis; DNA replication; male meiosis
尺寸1 :
0.1毫克
价格1 :
345美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。