产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
小鼠单克隆抗体抗人类ZW10
目录 :
MBS120277
规格 :
0.1毫克
价格 :
345美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
3363C4a
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
产品信息
目录号 :
MBS120277
产品类型 :
抗体
产品全称 :
小鼠单克隆抗体抗人类ZW10
产品简称 :
ZW10
产品名称同义词 :
Homo sapiens ZW10, kinetochore associated, homolog (Drosophila) (ZW10); HZW10; KNTC1AP; MGC149821
其他名称 :
Homo sapiens zw10 kinetochore protein (ZW10), mRNA; Centromere/kinetochore protein zw10 homolog; centromere/kinetochore protein zw10 homolog; ZW10 homolog, centromere/kinetochore protein; ZW10, kinetochore associated, homolog; zeste white 10 homolog; zw10 kinetochore protein
产品基因名称 :
ZW10
其他基因名称 :
ZW10;ZW10;HZW10;KNTC1AP
UniProt数据库进入名 :
ZW10_HUMAN
克隆性 :
单克隆
抗体亚型 :
IgG1
克隆 :
3363C4a
宿主 :
小鼠
反应物种 :
人类
序列长度 :
2964
浓度 :
100微克/毫升(1.0毫升)
检测过的应用 :
Dot Blot (DB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB)
其它信息1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
其他信息2 :
Sterility: Filtered through a 0.22 um membrane.
产品描述 :
The interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. May participate in cellular volume control by activation of a swelling-induced chloride conductance pathway. [UniProtKB Function]
NCBI GI登录号 :
342837718
NCBI登录号 :
NP_004715.1
NCBI基因登录号 :
NM_004724
NCBI分子量 :
76,807 Da
NCBI信号通路 :
Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); M Phase Pathway (105812); Mitotic Anaphase Pathway (105818); Mitotic Metaphase And Anaphase Pathway (730317); Mitotic Prometaphase Pathway (105815); Resolution Of Sister Chromatid Cohesion Pathway (730315); Separation Of Sister Chromatids Pathway (730318)
NCBI总结 :
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. [provided by RefSeq, Aug 2011]
UniProt数据库总结 :
ZW10: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum. Belongs to the ZW10 family. Protein type: Cell cycle regulation. Chromosomal Location of Human Ortholog: 11q23.2. Cellular Component: kinetochore; kinetochore microtubule; spindle pole; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; cytoplasm; nucleus; cytosol. Molecular Function: centromeric DNA binding; protein binding. Biological Process: meiosis; protein transport; ER to Golgi vesicle-mediated transport; establishment of mitotic spindle orientation; mitotic sister chromatid segregation; cell division; mitotic cell cycle checkpoint; regulation of exit from mitosis; protein complex assembly; mitotic cell cycle; Golgi organization and biogenesis; mitotic metaphase plate congression
尺寸1 :
0.1毫克
价格1 :
345美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。