产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
AICDA多克隆抗体
目录 :
MBS125279
规格 :
0.05毫升
价格 :
285美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹
更多信息或购买 :
MyBioSource 产品网页
产品信息
目录号 :
MBS125279
产品类型 :
抗体
产品全称 :
AICDA多克隆抗体
产品简称 :
AICDA
产品名称同义词 :
AID: AID;ARP2;CDA2;HIGM2
其他名称 :
Single-stranded DNA cytosine deaminase; Single-stranded DNA cytosine deaminase; single-stranded DNA cytosine deaminase; cytidine aminohydrolase; epididymis secretory protein Li 284; integrated into Burkitt's lymphoma cell line Ramos; activation-induced cytidine deaminase; Activation-induced cytidine deaminase; Cytidine aminohydrolase
产品基因名称 :
AICDA
其他基因名称 :
AICDA;AICDA;AID;ARP2;CDA2;HIGM2;HEL-S-284;AID
UniProt数据库进入名 :
AICDA_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
198
纯度 :
亲和纯化
浓度 :
1毫克/毫升
储存稳定性 :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
检测过的应用 :
免疫印迹(免疫印迹)
应用笔记 :
WB: 1:500 - 1:2000
其它信息1 :
Species: Human. Immunogen: Recombinant Protein
其他信息2 :
Immunogen: Recombinant protein of human AICDA. Calculated Molecular Weight: 24kDa
产品种类 :
多克隆
产品描述 :
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009]
NCBI GI登录号 :
23813666
NCBI登录号 :
Q9GZX7.1
UniProt数据库登录号 :
Q9GZX7
NCBI分子量 :
198
NCBI信号通路 :
IL4-mediated Signaling Events Pathway (137933); Intestinal Immune Network For IgA Production Pathway (128760); Intestinal Immune Network For IgA Production Pathway (128670); Primary Immunodeficiency Pathway (83125); Primary Immunodeficiency Pathway (537)
NCBI总结 :
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009]
UniProt数据库总结 :
AID: Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class- switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. Strongly expressed in lymph nodes and tonsils. Belongs to the cytidine and deoxycytidylate deaminase family. Protein type: EC 3.5.4.38; Hydrolase. Chromosomal Location of Human Ortholog: 12p13. Cellular Component: cytoplasm; exosome (RNase complex); nucleus. Molecular Function: protein binding; zinc ion binding; ubiquitin protein ligase binding; cytidine deaminase activity. Biological Process: somatic diversification of immunoglobulins; B cell differentiation; somatic hypermutation of immunoglobulin genes; isotype switching; cytidine deamination; mRNA processing. Disease: Immunodeficiency With Hyper-igm, Type 2
尺寸1 :
0.05毫升
价格1 :
285美元
尺寸2 :
0.2毫升
价格2 :
555
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。