抗体

YAP1多克隆抗体

MBS125438

0.05毫升

285美元

多克隆

兔

未共轭

人类, 小鼠

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 流式细胞仪

抗体

YAP1多克隆抗体

YAP1

YAP: AP;YAP2;YAP65;YKI

Transcriptional coactivator YAP1; Transcriptional coactivator YAP1; transcriptional coactivator YAP1; yorkie homolog; protein yorkie homolog; yes-associated protein 2; 65 kDa Yes-associated protein; yes-associated protein YAP65 homolog; Yes-associated protein 1; Protein yorkie homolog; Yes-associated protein YAP65 homolog

YAP1

YAP1; YAP1; YAP; YKI; COB1; YAP2; YAP65; YAP65; Yes-associated protein 1

YAP1_HUMAN

多克隆

IgG

兔

人类, 小鼠, 大鼠

504

亲和纯化

1毫克/毫升

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF), 免疫沉淀(免疫沉淀), 流式细胞仪(FC/流式细胞仪)

WB: 1:500 - 1:2000。 IHC: 1:50 - 1:200。 IF: 1:20 - 1:200。 IP: 1:20 - 1:200。 FC: 1:20 - 1:50

Species: Human. Immunogen: Recombinant Protein

Immunogen: Recombinant protein of human YAP1. Calculated Molecular Weight: 54kDa

多克隆

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]

294862479

P46937.2

P46937

504

ErbB4 Signaling Events Pathway (137991); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Gene Expression Pathway (105937); Generic Transcription Pathway (105938); Hippo Signaling Pathway (1084759); Hippo Signaling Pathway (1108222); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976)

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]

YAP1: an adaptor protein that binds to HER4 and the SH3 domain of the Yes tyrosine kinase. Associates with multiple transcription factors in the nucleus, and appears to be a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. Contains a WW domain that is found in various structural, regulatory and signaling molecules. Protein type: Transcription, coactivator/corepressor; Oncoprotein. Chromosomal Location of Human Ortholog: 11q13. Cellular Component: nucleoplasm; transcription factor complex; membrane; cytoplasm; cell junction; cytosol; nucleus. Molecular Function: protein binding; transcription coactivator activity; chromatin binding; transcription corepressor activity. Biological Process: paraxial mesoderm development; transcription initiation from RNA polymerase II promoter; somatic stem cell maintenance; lateral mesoderm development; cell morphogenesis; negative regulation of epithelial cell differentiation; notochord development; positive regulation of organ growth; keratinocyte differentiation; cell proliferation; positive regulation of cell proliferation; gene expression; positive regulation of transcription from RNA polymerase II promoter; vasculogenesis; response to DNA damage stimulus. Disease: Coloboma, Ocular, With Or Without Hearing Impairment, Cleft Lip/palate, And/or Mental Retardation

0.05毫升

285美元

0.2毫升

555