产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
NCOA1多克隆抗体
目录 :
MBS125472
规格 :
0.05毫升
价格 :
285美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
产品信息
目录号 :
MBS125472
产品类型 :
抗体
产品全称 :
NCOA1多克隆抗体
产品简称 :
NCOA1
产品名称同义词 :
SRC-1: F-SRC-1;KAT13A;MGC129719;MGC129720;NCoA-1;RIP160;SRC-1;SRC1;bHLHe42;bHLHe74
其他名称 :
Nuclear receptor coactivator 1; Nuclear receptor coactivator 1; nuclear receptor coactivator 1; Hin-2 protein; PAX3/NCOA1 fusion protein; steroid receptor coactivator-1; renal carcinoma antigen NY-REN-52; class E basic helix-loop-helix protein 74; nuclear receptor coactivator 1; Class E basic helix-loop-helix protein 74; bHLHe74; Protein Hin-2; RIP160; Renal carcinoma antigen NY-REN-52; Steroid receptor coactivator 1; SRC-1
产品基因名称 :
NCOA1
其他基因名称 :
NCOA1;NCOA1;SRC1;KAT13A;RIP160;F-SRC-1;bHLHe42;bHLHe74;BHLHE74;SRC1;NCoA-1;bHLHe74;SRC-1
UniProt数据库进入名 :
NCOA1_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
人类, 小鼠
序列长度 :
1441
纯度 :
亲和纯化
浓度 :
1毫克/毫升
储存稳定性 :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
检测过的应用 :
免疫印迹(免疫印迹), 免疫组化(免疫组化)
应用笔记 :
WB: 1:500 - 1:1000。 IHC: 1:50 - 1:100
其它信息1 :
Species: Human. Route: Synthetic Peptide
其他信息2 :
Immunogen: A synthetic peptide of human NCOA1. Calculated Molecular Weight: 157kDa
产品种类 :
多克隆
产品描述 :
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
NCBI GI登录号 :
158518533
NCBI登录号 :
Q15788.3
UniProt数据库登录号 :
Q15788
NCBI分子量 :
1441
NCBI信号通路 :
Activation Of Gene Expression By SREBF (SREBP) Pathway (685552); Adipogenesis Pathway (198832); Androgen Receptor Signaling Pathway (198806); BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway (477138); Bile Acid And Bile Salt Metabolism Pathway (106144); Biological Oxidations Pathway (105698); Circadian Clock Pathway (187173); Cytochrome P450 - Arranged By Substrate Type Pathway (105700); Defective CYP11A1 Causes Adrenal Insufficiency, Congenital, With 46,XY Sex Reversal (AICSR) Pathway (1127640); Defective CYP11B1 Causes Adrenal Hyperplasia 4 (AH4) Pathway (1127641)
NCBI总结 :
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
SRC-1: a transcriptional coactivator for steroid and nuclear hormone receptors. A member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, and bHLH and PAS domains. Phosphorylated and activated via the mitogen-activated protein kinase pathway. Three alternatively spliced isoforms have been described. Protein type: DNA-binding; Acetyltransferase; Oncoprotein; EC 2.3.1.48; Nuclear receptor co-regulator; Transcription, coactivator/corepressor. Chromosomal Location of Human Ortholog: 2p23. Cellular Component: nucleoplasm; neuron projection; nuclear chromatin; cytoplasm. Molecular Function: ligand-dependent nuclear receptor binding; protein dimerization activity; transcription coactivator activity; protein N-terminus binding; retinoid X receptor binding; signal transducer activity; protein binding; histone acetyltransferase activity; enzyme binding; ligand-dependent nuclear receptor transcription coactivator activity; androgen receptor binding; protein complex binding; estrogen receptor binding; chromatin binding; progesterone receptor binding; nuclear hormone receptor binding. Biological Process: lactation; hypothalamus development; positive regulation of transcription from RNA polymerase II promoter by galactose; male mating behavior; intracellular receptor-mediated signaling pathway; response to retinoic acid; transcription, DNA-dependent; positive regulation of apoptosis; positive regulation of transcription, DNA-dependent; male gonad development; hippocampus development; positive regulation of female receptivity; cellular lipid metabolic process; response to estradiol stimulus; cellular response to hormone stimulus; ovulation cycle; androgen receptor signaling pathway; cerebellum development; positive regulation of transcription from RNA polymerase II promoter; cerebral cortex development; positive regulation of neuron differentiation; response to progesterone stimulus
尺寸1 :
0.05毫升
价格1 :
285美元
尺寸2 :
0.2毫升
价格2 :
555
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。