VDAC1多克隆抗体 | MyBioSource MBS126096 产品信息

产品简要

公司名称 :

MyBioSource

产品类型 :

抗体

产品名称 :

VDAC1多克隆抗体

MBS126096

规格 :

0.05毫克

价格 :

230美元

克隆性 :

多克隆

宿主 :

兔

共轭标签 :

未共轭

反应物种 :

人类, 小鼠, 大鼠

应用 :

免疫印迹, 免疫组化

更多信息或购买 :

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产品信息

目录号 :

MBS126096

产品类型 :

抗体

产品全称 :

VDAC1多克隆抗体

产品简称 :

VDAC1

产品名称同义词 :

VDAC1;MGC111064;孔蛋白;孔蛋白-31

其他名称 :

Voltage-dependent anion-selective channel protein 1; Voltage-dependent anion-selective channel protein 1; voltage-dependent anion-selective channel protein 1; porin 31HL; porin 31HM; plasmalemmal porin; outer mitochondrial membrane protein porin 1; voltage-dependent anion channel 1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM

产品基因名称 :

VDAC1

其他基因名称 :

VDAC1;VDAC1;孔蛋白;VDAC-1;VDAC;VDAC-1;hVDAC1

UniProt数据库进入名 :

VDAC1_HUMAN

克隆性 :

多克隆

抗体亚型 :

IgG

宿主 :

兔

反应物种 :

人类, 小鼠, 大鼠

序列长度 :

283

纯度 :

亲和纯化

浓度 :

1毫克/毫升

储存稳定性 :

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

检测过的应用 :

免疫印迹(免疫印迹), 免疫组化(免疫组化)

应用笔记 :

WB: 1:500 - 1:2000。 IHC: 1:50 - 1:200。 IF: 1:50 - 1:200

其它信息1 :

Species: Human. Route: Recombinant Protein

其他信息2 :

Immunogen: Recombinant protein of human VDAC1. Calculated Molecular Weight: 31kDa

产品种类 :

多克隆

产品描述 :

Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria (1). In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics (2). Homodimerization of VDAC may be a mechanism for changing mitochondrial permeability and supporting release of cytochrome c (3). In mammalian cells, there are three VDAC isoforms, VDAC1, which is the most widely expressed isoform, as well as VDAC2 and VDAC3 (4,5).

NCBI GI登录号 :

130683

NCBI登录号 :

P21796.2

UniProt数据库登录号 :

P21796

NCBI分子量 :

283

NCBI信号通路 :

Calcium Signaling Pathway 83050!!Calcium Signaling Pathway 459!!HTLV-I Infection Pathway 373901!!HTLV-I Infection Pathway 373889!!Huntington's Disease Pathway 83100!!Huntington's Disease Pathway 512!!Influenza A Pathway 217173!!Influenza A Pathway 217150!!Metabolism Of Proteins Pathway 106230!!Mitochondrial Protein Import Pathway 576261

NCBI总结 :

This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.[provided by RefSeq, Sep 2010]

规格 :

0.05毫克

价格 :

230美元

更多信息或购买 :

MyBioSource 产品网页

公司信息