抗体

组蛋白H4R3me2a多克隆抗体

MBS126223

0.05毫升

265美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀

抗体

组蛋白H4R3me2a多克隆抗体

H4R3me2a

Asymmetric DiMethyl-Histone H4-R3: H3t; H3.4; H3/g; H3FT

Histone H4; Histone H4; histone H4; histone 2, H4a; H4 histone, family 2; histone IV, family 2; H4 histone family, member N; histone cluster 2, H4a

H4R3me2a

HIST2H4A;HIST1H4A;H4;H4/n;H4F2;H4FN;FO108;HIST2H4;H4/A;H4FA

H4_HUMAN

IgG

兔

Human, Mouse, Rat, Other (Wide Range)

103

亲和纯化

1毫克/毫升

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF), 免疫沉淀(免疫沉淀)

WB: 1:500 - 1:2000。 IHC: 1:50 - 1:200。 IF: 1:50 - 1:200。 IP: 1:50 - 1:100

Species: Human. Route: Synthetic Peptide

Immunogen: A synthetic methylated peptide corresponding to residues surrounding Arg3 of human histone H4. Calculated Molecular Weight: 11kDa

甲基化

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element.

51317339

P62805.2

P62805

Alcoholism Pathway (585563); Alcoholism Pathway (587116); Amyloids Pathway (366238); Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); Cellular Senescence Pathway (905991); Cellular Responses To Stress Pathway (645258); Chromatin Modifying Enzymes Pathway (1127682); Chromatin Organization Pathway (1127681); Chromosome Maintenance Pathway (161048)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. [provided by RefSeq, Jul 2008]

H4: histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The gene encoding H4 is intronless. Protein type: DNA-binding. Chromosomal Location of Human Ortholog: 6p22.2. Cellular Component: nucleoplasm; nuclear chromosome; protein complex; membrane; extracellular region; nucleosome; nucleus. Molecular Function: protein binding; DNA binding; histone binding; protein heterodimerization activity. Biological Process: chromatin silencing at rDNA; nucleosome assembly; establishment and/or maintenance of chromatin architecture; DNA replication-independent nucleosome assembly at centromere; DNA replication-independent nucleosome assembly; negative regulation of gene expression, epigenetic; protein heterotetramerization; gene expression; mitotic cell cycle; DNA methylation on cytosine; regulation of gene expression, epigenetic; DNA replication-dependent nucleosome assembly; telomere maintenance; negative regulation of megakaryocyte differentiation

0.05毫升

265美元

0.1毫升

380

0.2毫升

555