产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
CD33多克隆抗体
目录 :
MBS127495
规格 :
0.05毫升
价格 :
200美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学
更多信息或购买 :
MyBioSource 产品网页
图像
图像 1 :
MyBioSource MBS127495 图像 1
Western blot analysis of extracts of various cell lines, using CD33 Antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
图像 2 :
MyBioSource MBS127495 图像 2
Immunohistochemistry of paraffin-embdded human tonsil using CD33 antibody at dilution of 1:100 (40x lens).
图像 3 :
MyBioSource MBS127495 图像 3
Immunofluorescence analysis of THP-1 cells using CD33 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
产品信息
目录号 :
MBS127495
产品类型 :
抗体
产品全称 :
CD33多克隆抗体
产品简称 :
[CD33]
产品名称同义词 :
[FLJ00391;SIGLEC-3;SIGLEC3;p67]
其他名称 :
[Myeloid cell surface antigen CD33; Myeloid cell surface antigen CD33; myeloid cell surface antigen CD33; gp67; CD33 antigen (gp67); sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; CD33 molecule; Sialic acid-binding Ig-like lectin 3; Siglec-3; gp67; CD_antigen: CD33]
产品基因名称 :
[CD33]
其他基因名称 :
[CD33; CD33; p67; SIGLEC3; SIGLEC-3; SIGLEC3; Siglec-3]
UniProt数据库进入名 :
CD33_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
364
纯度 :
亲和纯化
储存稳定性 :
Store at -20 degree c. Avoid freeze / thaw cycles.
检测过的应用 :
免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF)
应用笔记 :
WB: 1:500 - 1:2000。 IHC: 1:50 - 1:200
image1头 :
免疫印迹(免疫印迹)
image2头 :
免疫组化
image3头 :
免疫荧光
其它信息1 :
Species: Human. Immunogen: Recombinant Protein
其他信息2 :
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 49-259 of human CD33 (NP_001763.3). Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
产品种类 :
多克隆
产品描述 :
CD33 is a type I transmembrane glycoprotein that is found on granulocyte and macrophage precursors in the bone marrow, but is absent from pluripotent stem cells. CD33 is also expressed on monocytes in peripheral blood. It is used as a marker to distinguish myelogenous leukemia cells from lymphoid or erythroid leukemias. CD33 may function as a sialic acid-dependent cell adhesion molecule.
NCBI GI登录号 :
116241290
NCBI登录号 :
P20138.2
UniProt数据库登录号 :
P20138
NCBI分子量 :
Calculated MW: 25kDa/33kDa/39kDa. Observed MW: 67kDa
NCBI信号通路 :
Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489)
UniProt数据库总结 :
CD33: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro). Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. Protein type: Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: 19q13.3. Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane. Molecular Function: protein binding; receptor activity; carbohydrate binding. Biological Process: negative regulation of cell proliferation; cell-cell signaling; signal transduction; cell adhesion
尺寸1 :
0.05毫升
价格1 :
200美元
尺寸2 :
0.1毫升
价格2 :
275
size3 :
0.2毫升
价格3 :
430
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。