产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
TLN1多克隆抗体
目录 :
MBS128619
规格 :
0.05毫升
价格 :
200美元
克隆性 :
多克隆
宿主 :
unidentified
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS128619 图像 1
Western blot analysis of extracts of U-87MG cells, using TLN1 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 20s.
产品信息
目录号 :
MBS128619
产品类型 :
抗体
产品全称 :
TLN1多克隆抗体
产品简称 :
[TLN1]
产品名称同义词 :
[TLN;ILWEQ]
其他名称 :
[踝蛋白1;踝蛋白1;踝蛋白1;踝蛋白1]
产品基因名称 :
[TLN1]
其他基因名称 :
[TLN1;TLN1;TLN;ILWEQ;KIAA1027;TLN]
UniProt数据库进入名 :
TLN1_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
未知
反应物种 :
人类
序列长度 :
2541
纯度 :
亲和纯化
储存稳定性 :
Store at -20 degree C. Avoid freeze/thaw cycles.
检测过的应用 :
免疫印迹(免疫印迹)
应用笔记 :
WB: 1:500 - 1:2000
image1头 :
免疫印迹(免疫印迹)
其它信息1 :
Immunogen: Recombinant Protein. Category: Primary Antibody. Source: Rabbit
其他信息2 :
Immunogen: Recombinant protein of human TLN1. Calculated Molecular Weight: 270kDa. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
产品种类 :
多克隆
产品描述 :
This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.
NCBI GI登录号 :
81175200
NCBI登录号 :
Q9Y490.3
UniProt数据库登录号 :
Q9Y490
NCBI分子量 :
2541
NCBI信号通路 :
Axon Guidance Pathway (105688); Developmental Biology Pathway (477129); EGF Receptor (ErbB1) Signaling Pathway (137970); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); GRB2:SOS Provides Linkage To MAPK Signaling For Integrins Pathway (106055); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); Hemostasis Pathway (106028)
NCBI总结 :
This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009]
UniProt数据库总结 :
Talin-1: a cytoskeletal protein which is concentrated in areas of cell-substratum and cell-cell contacts. This protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 9p13. Cellular Component: ruffle; cell surface; focal adhesion; cytoplasm; plasma membrane; extracellular region; microtubule organizing center; intercellular junction; cytosol. Molecular Function: integrin binding; actin filament binding; LIM domain binding; protein binding; structural constituent of cytoskeleton; insulin receptor binding; vinculin binding. Biological Process: platelet activation; intercellular junction assembly; axon guidance; unfolded protein response; cytoskeletal anchoring; cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; platelet degranulation; muscle contraction; cell-substrate junction assembly; cortical actin cytoskeleton organization and biogenesis; cell motility; blood coagulation
尺寸1 :
0.05毫升
价格1 :
200美元
尺寸2 :
0.1毫升
价格2 :
275
size3 :
0.2毫升
价格3 :
430
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。