抗体

小鼠抗p53

MBS140121

0.1毫克

375美元

单克隆

小鼠

未共轭

PP53SHG

免疫印迹, 免疫沉淀

抗体

小鼠抗p53

p53

p53抗体;p53, 小鼠抗体

cellular tumor antigen p53 isoform a; Cellular tumor antigen p53; cellular tumor antigen p53; antigen NY-CO-13; mutant tumor protein 53; p53 tumor suppressor; phosphoprotein p53; transformation-related protein 53; tumor protein p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53

p53

TP53;TP53;P53;BCC7;LFS1;TRP53;P53

P53_HUMAN

单克隆

IgG2a

PP53SHG

小鼠

393

1xPBS & 50% glycerol. Sterile Filtered solution.

免疫印迹(免疫印迹), 免疫沉淀(免疫沉淀)

Western Blotting: 2ug/ml.

单克隆/多克隆ANTIBODIES, MISCELLANEOUS ANTIBODIES;单克隆抗体

Description: Monoclonal antibodies are produced by immunizing mouse with full length His-tagged p53 protein. Introduction: p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

120407068

NP_000537.3

NM_000546.5

24,401 Da

AMPK Signaling Pathway 198868!!Activation Of BH3-only Proteins Pathway 105658!!Activation Of NOXA And Translocation To Mitochondria Pathway 105660!!Activation Of PUMA And Translocation To Mitochondria Pathway 105661!!Alzheimers Disease Pathway 672448!!Amyotrophic Lateral Sclerosis (ALS) Pathway 920975!!Amyotrophic Lateral Sclerosis (ALS) Pathway 83099!!Amyotrophic Lateral Sclerosis (ALS) Pathway 511!!Apoptosis Pathway 198797!!Apoptosis Pathway 83060

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]

0.1毫克

375美元