抗体

小鼠抗人类热休克蛋白27

MBS140204

0.02毫克

205美元

单克隆

小鼠

未共轭

P2A5AT

免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法

抗体

小鼠抗人类热休克蛋白27

热休克蛋白27

HSP27 Antibody; Heat Shock Protein 27, Mouse Anti Human; HSPB1; CMT2F; HMN2B; HSP27; HSP28; HSP25; Heat shock protein beta-1; Heat shock 27 kDa protein; Stress-responsive protein 27; SRP27; HS.76067; DKFZp586P1322

heat shock protein beta-1; Heat shock protein beta-1; heat shock protein beta-1; 28 kDa heat shock protein; HSP 27; epididymis secretory protein Li 102; estrogen-regulated 24 kDa protein; heat shock 27 kDa protein; heat shock 27kD protein 1; stress-responsive protein 27; heat shock 27kDa protein 1; 28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27

HSP27

HSPB1;HSPB1;CMT2F;HMN2B;HSP27;HSP28;Hsp25;SRP27;HS.76067;HEL-S-102;HSP27;HSP28;HspB1;HSP 27;SRP27

HSPB1_HUMAN

单克隆

IgG1 heavy chain and kappa light chain

P2A5AT

小鼠

205

HSP27 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.

1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. Sterile Filtered colorless solution.

For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫组化(免疫组化)

HSP27 antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:1,000~1:2,000 and immunohistochemistry analysis is 1:50~100. Recommended starting dilution for Western blot is 1:1,000 and Immunohistochemistry is 1:50.

Immunogen: Anti-human HSP27 mAb, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HSP27 amino acids 1-205 purified from E Coli.

单克隆抗体, 抗人类加热休克PROTEINS;单克隆抗体;抗人类热休克蛋白

Introduction: HSP27 (also known as the Estrogen-Regulated 24K protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 (p38).

4504517

NP_001531.1

NM_001540.3

22,783 Da

AUF1 (hnRNP D0) Destabilizes MRNA Pathway 187212!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Epstein-Barr Virus Infection Pathway 585562!!Epstein-Barr Virus Infection Pathway 587115!!FAS Pathway And Stress Induction Of HSP Regulation 198894!!Gene Expression Pathway 105937!!IL-3 Signaling Pathway 198881!!IL-6 Signaling Pathway 198864!!MAPK Signaling Pathway 198779

The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). [provided by RefSeq, Oct 2008]

0.02毫克

205美元