抗体

小鼠抗人类同源异形盒蛋白NANOG

MBS140269

0.02毫克

205美元

单克隆

小鼠

未共轭

P5A10AT

免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法

抗体

小鼠抗人类同源异形盒蛋白NANOG

同源异形盒蛋白NANOG

NANOG Antibody; Homeobox Protein NANOG, Mouse Anti Human; NANOG; Homeobox protein NANOG; Homeobox transcription factor Nanog; hNanog

homeobox protein NANOG isoform 1; Homeobox protein NANOG; homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog homeobox; Homeobox transcription factor Nanog; hNanog

NANOG

NANOG; NANOG; hNanog

NANOG_HUMAN

单克隆

IgG2a heavy chain and kappa light chain

P5A10AT

小鼠

305

NANOG antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.

1毫克/毫升含PBS, pH值7.4, &0.1% 叠氮化钠

For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫组化(免疫组化)

NANOG antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:500~1:1,000 and immunohistochemistry analysis is 1:50~100. Recommended starting dilution for Western blot is 1:500 and Immunohistochemistry is 1:50.

Immunogen: Anti-human NANOG mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NANOG amino acids 1-154 purified from E Coli.

单克隆/多克隆ANTIBODIES, MISCELLANEOUS ANTIBODIES;单克隆抗体

Introduction: NANOG is a multidomain homeobox transcription factor which functions to maintain the undifferentiated state of pluripotent stem cells. NANOG expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.

153945816

NP_079141.2

NM_024865.3

32,838 Da

Cardiac Progenitor Differentiation Pathway 712094!!Developmental Biology Pathway 477129!!POU5F1 (OCT4), SOX2, NANOG Activate Genes Related To Proliferation Pathway 1127697!!POU5F1 (OCT4), SOX2, NANOG Repress Genes Related To Differentiation Pathway 1127698!!Proteoglycans In Cancer Pathway 782000!!Proteoglycans In Cancer Pathway 782054!!SIDS Susceptibility Pathways 198901!!Signaling Pathways Regulating Pluripotency Of Stem Cells 1026136!!Signaling Pathways Regulating Pluripotency Of Stem Cells 1033502!!Transcriptional Regulation Of Pluripotent Stem Cells Pathway 1127696

0.02毫克

205美元