抗体

小鼠抗人类Toll样受体2

MBS140320

0.02毫克

205美元

单克隆

小鼠

nonconjugated

P1F10AT

免疫印迹, 酶联免疫吸附测定, 酶免疫法

抗体

小鼠抗人类Toll样受体2

Toll样受体2

TLR2 Antibody; Toll-like receptor 2, Mouse Anti Human; Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4; CD282; TLR2; TIL4

toll-like receptor 2; Toll-like receptor 2; toll-like receptor 2; toll/interleukin 1 receptor-like 4; toll/interleukin-1 receptor-like protein 4; toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4; CD_antigen: CD282

Toll样受体2

Toll样受体2;Toll样受体2;TIL4;CD282;TIL4

TLR2_HUMAN

单克隆

IgG1 heavy chain and kappa light chain

P1F10AT

小鼠

784

TLR2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.

1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. Sterile filtered colorless solution.

For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)

TLR2 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.

Immunogen: Anti-human TLR2 mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TLR2 amino acids 221-384 purified from E Coli.

单克隆/多克隆ANTIBODIES, MISCELLANEOUS ANTIBODIES;单克隆抗体

Introduction: TLR2 belongs to the Toll-like receptor (TLR) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) which are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

19718734

NP_003255.2

NM_003264.3

89,838 Da

Activated TLR4 Signalling Pathway 106400!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Beta Defensins Pathway 530759!!Chagas Disease (American Trypanosomiasis) Pathway 147809!!Chagas Disease (American Trypanosomiasis) Pathway 147795!!Defensins Pathway 530757!!Hepatitis B Pathway 694606!!Herpes Simplex Infection Pathway 377873!!Herpes Simplex Infection Pathway 377865

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq, Jul 2008]

0.02毫克

205美元