蛋白

小鼠β神经生长因子

MBS142316

0.02毫克

205美元

天然蛋白

小鼠β神经生长因子

β神经生长因子

b NGF Mouse; Beta-Nerve Growth Factor Mouse; Beta Polypeptide; NGF; NGFB; HSAN5; Beta-NGF; MGC161426; MGC161428

beta-nerve growth factor isoform B; Beta-nerve growth factor; beta-nerve growth factor; beta-NGF; nerve growth factor, beta; nerve growth factor

mb NGF

Ngf; Ngf; Ngfb; Ngfb; Beta-NGF

NGF_MOUSE

Submaxillary Gland of Grown Mouse

241

SSTHPVFHMGEF SVCDSVSVWV GDKTTATDIK GKEVTVLAEV NINNSVFRQY FFETKCRASN PVESGCRGID SKHWNSYCTT THTFVKALTT DEKQAAWRFI RIDTACVCVL SRKATRRG

Greater than 98% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

The NGF beta Mouse was lyophilized from solution containing 5% mannitol and 1% HSA. Sterile Filtered White lyophilized (freeze-dried) powder.

Lyophilized Mouse Beta-NGF although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Murine NGF-Beta should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.

Solubility: It is recommended to reconstitute the lyophilized Murine NGF-beta in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The method used to test the bioassay is the NGF-dependent survival of dorsal root ganglia neurons of chick embryo, corresponding to a Specific Activity of 500,000IU/mg.

CYTOKINES和增长FACTORS;神经营养因子;β神经生长因子

Description: NGF beta Mouse produced in Submaxillary Gland of Grown Mouse is a homodimer, non-glycosylated, polypeptide chain containing 2 identical 120 amino acids and having a molecular mass of 13,471 Dalton each.The NGF beta Mouse is purified by advanced biology purification technology. Introduction: NGF-beta has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.

V aron S, Raibo rn C. Dissociation, fractionation and culture ofchick embryo sympathetic ganglionic cells [ J ]. J N eu rocy tol, 1972; 1: 211- 221.

162951831

NP_001106168.1

NM_001112698.2

P01139

27,077 Da

ARMS-mediated Activation Pathway 1110440!!Activation Of TRKA Receptors Pathway 1110431!!Apoptosis Pathway 83257!!Apoptosis Pathway 470!!Apoptosis Signaling Pathway 522973!!Axonal Growth Stimulation Pathway 1110427!!Cell Death Signalling Via NRAGE, NRIF And NADE Pathway 1110417!!Ceramide Signalling Pathway 1110425!!Frs2-mediated Activation Pathway 1110439!!Id Signaling Pathway 198411

0.02毫克

205美元