蛋白

重组人类热休克蛋白90甲

MBS142709

0.005毫克

140美元

重组蛋白

重组人类热休克蛋白90甲

热休克蛋白90甲

HSP90 Alpha Human; Heat Shock Protein-90 Alpha Human Recombinant; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; HSP90A; HSP90N; HSPCAL1; HSPCAL4; FLJ31884; Heat shock protein HSP 90-alpha; Renal carcinoma antigen NY-REN-38; HSP 86; HSP90AA1

heat shock protein HSP 90-alpha isoform 1; Heat shock protein HSP 90-alpha; heat shock protein HSP 90-alpha; HSP 86; LPS-associated protein 2; epididymis luminal secretory protein 52; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kD protein 1, alpha-like 4; heat shock 90kD protein, alpha-like 4; heat shock 90kDa protein 1, alpha; lipopolysaccharide-associated protein 2; renal carcinoma antigen NY-REN-38; heat shock protein 90kDa alpha (cytosolic), class A member 1; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38

HSP90

HSP90AA1; HSP90AA1; EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4; HSP90A; HSPC1; HSPCA; HSP 86; HSP86; LAP-2; LPS-associated protein 2

HS90A_HUMAN

大肠杆菌

854

Greater than 90.0% as determined by SDS-PAGE.

The HSP90 protein solution contains 20mM Tris-HCl, pH-7.4 and 100mM NaCl. Sterile filtered colorless solution.

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

加热休克PROTEINS;重组蛋白;热休克蛋白

Description: Recombinant Human HSP-90 produced in E Coli is a single, non-glycosylated polypeptide chain (aa 1-732) containing 752 amino acids and having a molecular mass of 86.8kDa. HSP90 is expressed with a 20 amino acid His tag at N-Terminus and purified by proprietary chromatographic techniques. Introduction: HSP90 has been identified in the cytosol, nucleus and endoplasmic reticulum, and is reported to exist in many tissue types. In several tissues, including smooth muscle, HSP90 comprises up to 2% of total cellular protein. HSP90 functions as a dimer, assembled as part of heterocomplex. It possesses ATP-binding site and low ATPase activity. HSP90 is able to associate with actin filaments in certain conditions. Another important property of HSP90 is the binding of unoccupied steroid hormone receptors. HSP90 has been characterized as a molecular chaperone able to keep the target protein in a folding-competent state. It has an enhanced chaperone activity in oligomeric form at high temperatures. HSP90 function is sensitive to bivalent cations concentration.

153792590

NP_001017963.2

NM_001017963.2

P07900

98,161 Da

AhR Pathway (755436); Anchoring Of The Basal Body To The Plasma Membrane Pathway (1127503); Antigen Processing And Presentation Pathway (83074); Antigen Processing And Presentation Pathway (485); Assembly Of The Primary Cilium Pathway (1127502); Attenuation Phase Pathway (1127556); Axon Guidance Pathway (105688); Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765)

The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

HSP90A: a molecular chaperone of the heat shock protein 90 family. Has ATPase activity. Known to interact with a wide variety of proteins including steroid hormone receptors, neuropeptide Y, FKBP51/54, and FKBP52. G protein-coupled receptor kinases are stabilized by interacting with HSP 90. Hsp70 and Hsp90 promote tau solubility and tau binding to microtubules, reducing insoluble tau phosphorylation of tau. Protein type: Chaperone; Heat shock protein. Chromosomal Location of Human Ortholog: 14q32.33. Cellular Component: nucleoplasm; membrane; mitochondrion; cytoplasm; melanosome; plasma membrane; extracellular region; cytosol; nucleus. Molecular Function: identical protein binding; protein binding; protein homodimerization activity; TPR domain binding; unfolded protein binding; nitric-oxide synthase regulator activity; ATPase activity; nucleotide binding; ATP binding. Biological Process: receptor-mediated endocytosis; axon guidance; positive regulation of nitric oxide biosynthetic process; organelle organization and biogenesis; signal transduction; protein import into mitochondrial outer membrane; nitric oxide metabolic process; response to unfolded protein; mitochondrial transport; innate immune response; protein refolding; mitotic cell cycle; regulation of nitric-oxide synthase activity; chaperone-mediated protein complex assembly; G2/M transition of mitotic cell cycle; vascular endothelial growth factor receptor signaling pathway

0.005毫克

140美元

0.02毫克

205

1毫克

3490