抗体

NANOG抗体

MBS150440

0.1毫克

345美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 酶免疫法

抗体

NANOG抗体

NANOG

NANOG; Homeobox protein NANOG; Homeobox transcription factor Nanog; hNanog; Nanog homeobox

Nanog homeobox, isoform CRA_a; Homeobox protein NANOG; homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog homeobox; Homeobox transcription factor Nanog; hNanog

NANOG

NANOG; NANOG; hNanog

NANOG_HUMAN

多克隆

IgG

兔

人类, 小鼠, 大鼠

305

NANOG Antibody is affinity chromatography purified via peptide column.

液体

1毫克/毫升

NANOG antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF)

NANOG antibody can be used for detection of NANOG by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Conjugate: Unconjugated. Immunogen: NANOG antibody was raised against a 19 amino acid synthetic peptide near the center of human NANOG. Buffer: NANOG Antibody is supplied in PBS containing 0.02% sodium azide.

NANOG Antibody: Expression of NANOG is required for the maintenance of pluripotency in epiblast and embryonic stem (ES) cells as well as for the ability to maintain ES self-renewal independently of LIF/Stat3. The role of NANOG in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 (also known as Oct-4), another germline-specific transcription factor, and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing NANOG, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.

119609057

EAW88651

Q9H9S0

32,838 Da

Cardiac Progenitor Differentiation Pathway 712094!!Developmental Biology Pathway 477129!!POU5F1 (OCT4), SOX2, NANOG Activate Genes Related To Proliferation Pathway 1127697!!POU5F1 (OCT4), SOX2, NANOG Repress Genes Related To Differentiation Pathway 1127698!!Proteoglycans In Cancer Pathway 782000!!Proteoglycans In Cancer Pathway 782054!!SIDS Susceptibility Pathways 198901!!Signaling Pathways Regulating Pluripotency Of Stem Cells 1026136!!Signaling Pathways Regulating Pluripotency Of Stem Cells 1033502!!Transcriptional Regulation Of Pluripotent Stem Cells Pathway 1127696

0.1毫克

345美元