产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
ZEB1抗体
目录 :
MBS151570
规格 :
0.1毫克
价格 :
345美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS151570
产品类型 :
抗体
产品全称 :
ZEB1抗体
产品简称 :
ZEB1
产品名称同义词 :
ZEB1;BZP;TCF8;AREB6;FECD6;NIL2A;PPCD3;ZFHEP;ZFHX1A;DELTAEF1;锌指E拳击同源异形盒1;NIL-2锌指蛋白;TCF-8;锌指E拳击结合同源异形盒1
其他名称 :
Zinc finger E-box-binding homeobox 1; zinc finger E-box-binding homeobox 1; negative regulator of IL2; delta-crystallin enhancer binding factor 1; posterior polymorphous corneal dystrophy 3; zinc finger homeodomain enhancer-binding protein; transcription factor 8 (represses interleukin 2 expression); zinc finger E-box binding homeobox 1; NIL-2-A zinc finger protein; Negative regulator of IL2; Transcription factor 8; TCF-8
产品基因名称 :
ZEB1
其他基因名称 :
ZEB1;ZEB1;BZP;TCF8;AREB6;FECD6;NIL2A;PPCD3;ZFHEP;ZFHX1A;DELTAEF1;AREB6;TCF8;TCF-8
UniProt数据库进入名 :
ZEB1_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
人类
序列长度 :
1,108
特异性 :
Multiple isoforms of ZEB1 are known to exist.
纯度 :
ZEB1 Antibody is affinity chromatography purified via peptide column.
形式 :
液体
浓度 :
1毫克/毫升
储存稳定性 :
ZEB1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫细胞化学(免疫细胞化学), 免疫荧光(IF)
应用笔记 :
ZEB1 antibody can be used for detection of ZEB1 by Western blot at 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 20 mug/mL. For immunofluorescence start at 20 mug/mL.
其它信息1 :
Conjugate: Unconjugated. Immunogen: ZEB1 antibody was raised against a 15 amino acid synthetic peptide near the center of human ZEB1. Buffer: ZEB1 Antibody is supplied in PBS containing 0.02% sodium azide.
产品描述 :
ZEB1 Antibody: ZEB1, initially identified as the delta-crystallin enhancer binding protein delta EF1, is a DNA-binding protein that binds to a modified E-box sequence and has been implicated in postgastrulation embryogenesis. ZEB1 binds to the promoter of several hemapoietic genes, including interleukin-2, CD4, GATA-3, and alpha-integrin, and mice in which ZEB1 has been targeted show thymic atrophy, and severe defects in lymphocyte differentiation. Recent evidence suggests that ZEB1 also regulates the accumulation of adipose tissue and may play a role in obesity. Mutations in this gene have been associated with late-onset Fuchs endothelial corneal dystrophy.
NCBI GI登录号 :
55957123
NCBI登录号 :
NP_110378
UniProt数据库登录号 :
P37275
NCBI分子量 :
Predicted: 124 kDa. Observed: 130 kDa
NCBI信号通路 :
Hypertrophy Model Pathway 198828!!MicroRNAs In Cancer Pathway 852705!!MicroRNAs In Cancer Pathway 852928!!TGF-beta Receptor Signaling Pathway 198774!!Transcriptional Misregulation In Cancer Pathway 523016!!Transcriptional Misregulation In Cancer Pathway 522987
NCBI总结 :
This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010]
规格 :
0.1毫克
价格 :
345美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。