产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
α微管蛋白抗体
目录 :
MBS153509
规格 :
0.1毫克
价格 :
345美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS153509
产品类型 :
抗体
产品全称 :
α微管蛋白抗体
产品简称 :
α微管蛋白
产品名称同义词 :
α微管蛋白抗体;TUBA2;bA408E5.3;TUBA2;TUBA3D;α微管蛋白2
其他名称 :
微管蛋白甲3C/D链;微管蛋白甲3C/D链;微管蛋白甲3C/D链;α微管蛋白2;微管蛋白, 甲2;α微管蛋白3C/D;微管蛋白甲2链;微管蛋白, 甲3c;α微管蛋白2;α微管蛋白3C/D;微管蛋白甲2链
产品基因名称 :
TUBA3C
其他基因名称 :
TUBA3C;TUBA3C;TUBA2;bA408E5.3;TUBA2
UniProt数据库进入名 :
TBA3C_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
450
纯度 :
Alpha-tubulin Antibody is affinity chromatography purified via peptide column.
形式 :
液体
浓度 :
1毫克/毫升
储存稳定性 :
Alpha-tubulin antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)
应用笔记 :
Tubulin antibody can be used for detection of Tubulin by Western blot at 0.5 and 1 ug/mL. Optimal dilutions for each application to be determined by the researcer.
其它信息1 :
Conjugate: Unconjugated. Immunogen: Rabbit polyclonal Tubulin antibody was raised against a 16 amino acid peptide near the amino terminus of human Tubulin. Buffer: Alpha-tubulin Antibody is supplied in PBS containing 0.02% sodium azide.
其他信息2 :
Positive Control: MBS151663
产品描述 :
Alpha-tubulin Antibody: Alpha-tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Another post-translational modification of detyrosinated alpha-tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle. Like GAPDH and beta-Actin, this antibody makes an excellent loading control in immunoblots.
NCBI GI登录号 :
17921993
NCBI登录号 :
NP_005992
NCBI基因登录号 :
NM_006001.2
UniProt数据库登录号 :
Q13748
NCBI分子量 :
Predicted: 50 kDa
NCBI信号通路 :
Chaperonin-mediated Protein Folding Pathway (106242); Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway (106243); Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway (106245); Gap Junction Pathway (83072); Gap Junction Pathway (483); Metabolism Of Proteins Pathway (106230); Parkin-Ubiquitin Proteasomal System Pathway (700638); Pathogenic Escherichia Coli Infection Pathway (83103); Pathogenic Escherichia Coli Infection Pathway (672459); Pathogenic Escherichia Coli Infection Pathway (516)
NCBI总结 :
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
TUBA3C/D: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Dimer of alpha and beta chains. Testis specific. Belongs to the tubulin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cytoskeletal; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 13q11. Cellular Component: microtubule; cytoplasm; nucleus. Molecular Function: GTPase activity; protein binding; GTP binding; structural constituent of cytoskeleton. Biological Process: protein polymerization; de novo posttranslational protein folding; cellular protein metabolic process; protein folding; microtubule-based process
尺寸1 :
0.1毫克
价格1 :
345美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。