ELISA/assay

Mouse Cathepsin B, cath-B ELISA Kit

MBS160147

48-Strip-Wells

280美元

酶联免疫吸附试剂盒

Mouse Cathepsin B, cath-B ELISA Kit

[Cathepsin B, cath-B]

[cathepsin B isoform 1 preproprotein; Cathepsin B; cathepsin B; cathepsin B; APP secretase; APPS]

[cath-B]

[CTSB;CTSB;APPS;CPSB;RECEUP;CPSB;APPS]

小鼠

339

Store at 2 to 8 degree C for 6 months.

22538437

NP_680093.1

NM_147783.3

P07858

37,822 Da

Adaptive Immune System Pathway (1269171); Antigen Processing And Presentation Pathway (83074); Antigen Processing And Presentation Pathway (485); Apoptosis Pathway (83060); Apoptosis Pathway (470); Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (1270247); Collagen Degradation Pathway (1270259); Collagen Formation Pathway (1270245); Degradation Of The Extracellular Matrix Pathway (1270257); Extracellular Matrix Organization Pathway (1270244)

This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Nov 2015]

Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.

48-Strip-Wells

280美元

96-Strip-Wells

445

5x96-Strip-Wells

1830

10x96-Strip-Wells

3580