MyBioSource

抗体

抗CXCR2抗体

MBS175134

0.1毫克

245美元

多克隆

兔

nonconjugated

MBS175134

抗体

抗CXCR2抗体

CXCR2

C-X-C chemokine receptor type 2(CXC-R2/CXCR-2); chemokine(C-X-C motif) receptor 2; C-X-C chemokine receptor type 2 antibody; CD 182 antibody; CD182 antibody; CD182 antigen antibody; CDw128b antibody; Chemokine(CXC) receptor 2 antibody; CMKAR2 antibody; CXC-R2 antibody; CXCR 2 antibody; CXCR-2 antibody; CXCR2 antibody; CXCR2_HUMAN antibody; GRO/MGSA receptor antibody; High affinity interleukin-8 receptor B antibody; IL 8 receptor type 2 antibody; IL 8R B antibody; IL-8 receptor type 2 antibody; IL-8R B antibody; IL8 RB antibody; IL8 receptor type 2 antibody; IL8R B antibody; IL8R2 antibody; IL8RA antibody; Interleukin 8 Receptor B antibody

C-X-C chemokine receptor type 2; C-X-C chemokine receptor type 2; C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; IL-8R B; GRO/MGSA receptor; IL-8 receptor type 2; interleukin 8 receptor B; chemokine (CXC) receptor 2; interleukin 8 receptor, beta; interleukin 8 receptor type 2; interleukin-8 receptor type B; CXCR2 gene for IL8 receptor type B; high affinity interleukin-8 receptor B; chemokine (C-X-C motif) receptor 2; CDw128b; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8R B; IL-8 receptor type 2; CD_antigen: CD182

CXCR2

CXCR2;CXCR2;CD182;IL8R2;白细胞介素-8ra;白细胞介素-8rb;CMKAR2;CDw128b;白细胞介素-8rb;CXC-R2;CXCR-2;IL-8R B

CXCR2_HUMAN

多克隆

IgG

兔

人类

360

免疫原亲和纯化

冻干

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

免疫印迹(免疫印迹)

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human CXCR2 (196-212aa CYEDMGNNTANWRMLLR), different from the related mouse sequence by six amino acids.

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Description: Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 2(CXCR2) detection. Tested with WB in Human. Background: CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family(subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.

1352454

P25025.2

P25025

40,759 Da

Chemokine Receptors Bind Chemokines Pathway 106359!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Endocytosis Pathway 102279!!Endocytosis Pathway 102181!!Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway 83102!!Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway 515

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009]

0.1毫克

245美元